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2-Chloro(Trifluoromethyl)Benzene

2-Chloro(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

138787

Chemical Formula C7H4ClF3
Molecular Weight 180.55
Appearance Colorless liquid
Boiling Point 156 - 158 °C
Density 1.328 g/cm³
Water Solubility Insoluble
Flash Point 46 °C
Refractive Index 1.452

As an accredited 2-Chloro(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle packaging for 2 - chloro(trifluoromethyl)benzene chemical.
Storage 2 - chloro(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or glass. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions.
Shipping 2 - chloro(trifluoromethyl)benzene is shipped in accordance with strict chemical transportation regulations. It's typically in well - sealed, corrosion - resistant containers, transported by specialized carriers ensuring proper handling to prevent spills and ensure safety.
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2-Chloro(Trifluoromethyl)Benzene 2-Chloro(Trifluoromethyl)Benzene
General Information
Historical Development
2-Chloro (trifluoromethyl) benzene is also an organic compound. Tracing its historical development, chemists in the past studied the technique of organic synthesis and strived to expand the variety of compounds. At that time, the exploration of fluorine-containing compounds gradually flourished, and the characteristics of cover fluorine were unique, which could make compounds have different properties.
In the process of synthesis research, various attempts emerged. Chemists used wisdom and skills to prepare various reactants and explore suitable conditions. After repeated experiments and adjustments, the method of synthesizing 2-chloro (trifluoromethyl) benzene was finally obtained.
At the beginning, the synthesis method was cumbersome and the yield was not high, but chemists made unremitting progress. With the improvement of chemical theory and technological innovation, the synthesis method is becoming more and more perfect, the yield is gradually increasing, and the purity is also excellent. Therefore, 2-chloro (trifluoromethyl) benzene has emerged in the field of organic synthesis, laying the foundation for many research and applications.
Product Overview
2-Chloro (trifluoromethyl) benzene is a kind of organic compound. Its properties are colorless to light yellow liquid at room temperature, with a special odor. This substance is widely used in the field of organic synthesis.
In its molecular structure, above the benzene ring, the chlorine atom is juxtaposed with the trifluoromethyl. Due to the strong electron-absorbing properties of trifluoromethyl, the chemical properties of this compound are unique. In electrophilic substitution reactions, its reactivity and orientation are affected by this structure.
The preparation method often uses specific benzene derivatives as the starting material, and is obtained through various reaction steps such as halogenation and trifluoromethylation. In organic synthesis, it is often used as an intermediate to build more complex organic molecules, and is of great value in many fields such as medicine, pesticides, and materials science. It can provide a key structural unit for the creation of new compounds.
Physical & Chemical Properties
2 - Chloro (Trifluoromethyl) Benzene is also an organic compound. It has special physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is appropriate, which is conducive to separation and purification. As for chemical properties, because it contains chlorine and trifluoromethyl, it has unique reactivity. Chlorine atoms can undergo nucleophilic substitution, while trifluoromethyl affects the distribution of molecular electron clouds, making the compound exhibit specific behaviors in electrophilic reactions. Chemists can use this property to synthesize a variety of substances with special functions. It has potential uses in the fields of medicine and materials. It is an important object of organic synthetic chemistry research and its value in the development of modern chemical industry.
Technical Specifications & Labeling
2-Chloro (Trifluoromethyl) Benzene is an important chemical raw material, and its preparation process and quality standards are crucial. The preparation of this product requires specific technical specifications. The selection of raw materials must be pure, and the reaction conditions should be precisely controlled. For example, the temperature should be maintained in a suitable range to ensure the smooth progress of the reaction. The regulation of pressure should not be underestimated.
When quality testing, it should be strictly determined according to the product parameters. The appearance should be colorless and transparent liquid, and the smell should also meet the standards. Purity determination requires the use of precision instruments, and the impurity content must be strictly controlled. Only by following this technical specification and quality determination (product parameters) can high-quality 2-Chloro (Trifluoromethyl) Benzene be produced to meet the needs of all parties and play its due role in the chemical industry.
Preparation Method
To make 2-chloro (trifluoromethyl) benzene, the raw materials and production process, reaction steps and catalytic mechanism are very important. First take an appropriate amount of o-chlorotoluene as the initial raw material, which is the basis of the reaction. In a special reactor, add an appropriate amount of anhydrous aluminum trichloride as a catalyst, carefully adjust the temperature to about 80-100 degrees Celsius. Then, slowly introduce a certain amount of chlorine gas to initiate a chlorination reaction. The process needs to pay close attention to the reaction progress and temperature fluctuations to ensure a smooth reaction. After the chlorination reaction is completed, the product is moved to another reaction vessel, add an appropriate amount of anhydrous hydrofluoric acid and potassium fluoride, and heat up to 150-180 degrees Celsius for fluorination reaction. This step requires strict control of the reaction conditions in order to make the fluorination process smooth and finally produce 2-chloro (trifluoromethyl) benzene. During the whole process, precise control of each reaction link and rational use of catalysts are the keys to ensuring the purity and yield of the product.
Chemical Reactions & Modifications
2-Chloro (trifluoromethyl) benzene is also an organic compound. In the field of chemistry, the discussion of reactions and modifications is quite important.
To investigate its reaction, the characteristics of halogenated aromatics make it possible to involve various reactions such as nucleophilic substitution. In case of nucleophilic reagents, chlorine atoms can be replaced. The reaction conditions are controlled to be severe, and temperature, solvent, and catalyst can all affect its process and yield.
As for modification, other groups can be introduced to improve its properties. Or modify the surrounding structure of trifluoromethyl to give the compound different physical and chemical properties, such as solubility, stability, and biological activity. The study of the reaction and modification of this compound has far-reaching significance in many fields such as medicine and materials. It can help develop new drugs, create high-performance materials, and contribute to the development of chemistry.
Synonyms & Product Names
2-Chloro (trifluoromethyl) benzene is particularly important in the study of chemical products. Its synonyms and trade names cannot be ignored.
A synonym for this substance, or named according to its structural characteristics. Because its chlorine atom and trifluoromethyl are based on the benzene ring, there is a synonym for this name to show the characteristics of its chemical structure.
As for trade names, merchants often give unique names in order to recognize the characteristics of their products or to distinguish them from the market. Or emphasize its purity, or highlight its specific use, which varies from business to business.
The study of chemical products, the identification of synonyms and trade names, is related to the accuracy of academic communication and the clarity of commercial promotion. For scholars, understanding the different names of this thing can lead to a smooth journey of research, without the risk of naming confusion, and accurately explore its chemical mysteries, so as to promote the development and progress of this field.
Safety & Operational Standards
Code for safety and operation of 2-chloro (trifluoromethyl) benzene
Fu 2-chloro (trifluoromethyl) benzene is a common chemical in chemical research and industrial production. If you want to make good use of this material, you must first clarify its safety and operation specifications to ensure the smooth operation of all things and the well-being of personnel.
The first word is the importance of storage. 2-chloro (trifluoromethyl) benzene should be placed in a cool and ventilated warehouse. Avoid open flames and hot topics, and keep away from fires. This is because it is flammable, and there is a risk of explosion in case of open flames and hot topics. The temperature of the warehouse should not exceed 30 ° C, and the relative humidity should not exceed 80%. And it should be stored separately from oxidants and edible chemicals, and must not be mixed to prevent dangerous chemical reactions.
Times and operating rules. Operators must be professionally trained and strictly follow the operating procedures. During operation, protective clothing, protective gloves and goggles are required to prevent skin and eye contact. Because of its irritation, if accidentally touched, it will cause disaster. The operating environment should be well ventilated to remove volatile gas.
Furthermore, it is related to emergency measures. If 2-chlorine (trifluoromethyl) benzene leaks, personnel in the contaminated area should be quickly evacuated to a safe place, and unrelated persons should be prohibited from entering. Emergency responders must wear protective clothing and gas masks, and do not directly contact the leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be embanketed and contained before treatment.
When transporting, there are also regulations. Make sure that the container is not damaged or leaked, drive according to the specified route, and do not stop in densely populated areas and residential areas.
In short, in the use, storage, and transportation of 2-chloro (trifluoromethyl) benzene, safety and operating standards should be strictly adhered to. In this way, disasters can be avoided and scientific research and production are safe and orderly.
Application Area
2-Chloro (trifluoromethyl) benzene, a chemical substance, has a wide range of applications. In the field of pharmaceutical synthesis, it can be a key intermediate and assist in the creation of many specific drugs. Due to its unique structure, it can endow drugs with specific activities and properties.
In the field of materials science, it also has its uses. Or it can participate in the preparation of high-performance materials, such as materials with special chemical stability and thermal stability. Its fluorine-containing structure can often improve the material's ability to resist external erosion.
In the field of pesticides, it is also indispensable. Using this as a raw material, it can develop efficient and low-toxicity pesticides, accurately target pests and diseases, protect agricultural production, and reduce environmental damage. Therefore, 2-chloro (trifluoromethyl) benzene has important value in various application fields and promotes the progress and development of related industries.
Research & Development
Today there is a thing named 2 - Chloro (Trifluoromethyl) Benzene, which is very important in the field of my chemical research. We have tried our best to explore its properties and study its quality.
Observe its chemical properties, observe the changes in its reactions, or under high temperatures, or in special circumstances, all of which are recorded in detail. Investigate the mystery of its structure, explore the principle of atomic connection, and understand its inner rules.
Study its preparation method, and strive to improve. Try different methods and choose the best way, hoping to improve the yield and increase its quality. After many attempts, we have gradually gained something, and the process has become more perfect.
As for the application, there is great potential. Or it can be used for the preparation of new drugs, or to help the renewal of materials. We hope that it will shine in the future and contribute to the progress of chemistry and the prosperity of society. With unremitting research, we hope to promote the development of this product and benefit the world.
Toxicity Research
"On the Toxicity of 2-Chloro (Trifluoromethyl) Benzene"
Fu 2-chloro (trifluoromethyl) benzene is an important object of chemical research. Today, its toxicity is studied in detail to clarify its properties and avoid its harm.
Observe its molecular structure, the genus of chlorine and trifluoromethyl, or cause special chemical activity. After various experiments, observe its impact on organisms. In animal experiments, after the subject is exposed to this substance, the physiological state gradually changes. Its respiratory and metabolic energy changes to varying degrees.
At the cellular level, it can cause cell morphology to be distorted and function to be destroyed. All of this shows that 2-chloro (trifluoromethyl) benzene has certain toxicity.
However, the research on toxicity does not stop there. When studying its dissipation and transformation in the environment, as well as its long-term impact on the ecological chain. Our chemical researchers must investigate carefully to ensure the safety of the environment and people.
Future Prospects
2-Chloro (trifluoromethyl) benzene, the future prospect of this substance, is related to the process of our chemical research. Its unique structure may open up new paths in the field of organic synthesis. In the future, it is expected to use advanced technology to optimize the synthesis process, increase yield and reduce costs.
In materials science, it may become a key raw material to make materials with special properties, such as weather resistance and chemical corrosion resistance, used in aerospace and high-end equipment. In pharmaceutical research and development, there is also potential, or it may be able to derive special drugs to overcome difficult diseases.
We should study it diligently, explore more possibilities, and use our wisdom and efforts to expand its application boundaries, pave the way for scientific progress and human well-being, and make it shine brightly in the future.
Where to Buy 2-Chloro(Trifluoromethyl)Benzene in China?
As a trusted 2-Chloro(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chloro(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-chloro (trifluoromethyl) benzene?
2-% cyanogen (triethylmethyl) naphthalene is widely used. In the field of medicine, it can be used as a raw material for the synthesis of specific drugs. The unique structure of this substance can give it special pharmacological activity when building drug molecules. For example, it can help develop new drugs for specific diseases, such as some stubborn inflammation or difficult diseases, which is expected to bring good news to patients.
In materials science, it also plays an important role. It can participate in the creation of high-performance materials. If it is copolymerized with other compounds, it can prepare new polymer materials with excellent physical properties, or enhance the toughness and heat resistance of materials, or endow them with special optical and electrical properties. It has potential applications in high-end fields such as aerospace and electronic equipment.
In chemical production, it is an important intermediate. Through a series of chemical reactions, a variety of high-value-added chemical products can be derived. By precisely controlling the reaction conditions, diverse transformations can be achieved, thereby enriching the types of chemical products, meeting the needs of different industries, and enhancing the economic efficiency and competitiveness of the chemical industry.
In terms of scientific research and exploration, it is an ideal model for studying the relationship between molecular structure and properties. Scientists can deeply explore basic scientific issues such as the interaction mechanism between molecules and the distribution change of electron clouds through chemical modification and modification, providing important experimental basis and data support for the improvement and expansion of organic chemistry theory.
What are the physical properties of 2-chloro (trifluoromethyl) benzene?
2-% (triethylmethyl) silicon, its physical properties are very special. This material is usually a liquid color, and the ground is clear. Under normal conditions, its external appearance resembles clear water, and its fluidity is very good.
It is difficult to melt. Due to the characteristics of molecular force, the molten phase is low, usually at a low temperature, so that this material is easy to be liquid at a slightly higher temperature than its melting temperature. As for the boiling temperature, it is not very high. Under certain conditions, it can be melted at a low temperature.
In terms of density, the density of 2-% (triethylmethyl) silicon is very small. If the water is co-located with it, it can float on the water surface, and the limit is clear.
Solubility is also one of its important physical properties. This substance is soluble in water, and it is not easy to dissolve due to the matching force of its molecules. However, in many soluble substances, such as ether, toluene, etc., it has good solubility and can be miscible to form a homogeneous solution.
In addition, the solubility of 2-% (triethyl) silicon is low. In the open environment, it can be quickly washed into the air. It has a certain smell and is not pungent. However, it also has its own special interest, which can be used to identify this material. The density of its evaporation phase is higher than that of the air. If it is high, it is easy to gather at low temperatures. This is important for use and storage.
What are the chemical properties of 2-chloro (trifluoromethyl) benzene?
The chemical properties of 2-% cyanogen (triethylmethyl) naphthalene can be investigated. In this compound, the cyanyl group has high reactivity. The carbon-nitrogen triple bond in the cyanyl group is rich in electrons, which makes the group easy to react with electrophilic reagents. In case of halogenated hydrocarbons, the carbon atoms of the cyanyl group can attack the α-carbon of halogenated hydrocarbons, and a nucleophilic substitution reaction occurs, thereby increasing the carbon chain. This is an important means of increasing carbon in organic synthesis.
Furthermore, the naphthalene ring has a fused ring aromatic hydrocarbon structure and has a certain aromaticity. The electron cloud distribution on the naphthalene ring has its own characteristics, and the electron cloud density at the α-position is relatively high, so the electrophilic substitution reaction often occurs at When this substance encounters electrophilic reagents, such as halogenating agents, nitrifying agents, etc., the electrophilic reagents are prone to attack the alpha-position of the naphthalene ring and generate corresponding substitution products.
And triethyl methyl is attached to the naphthalene ring, which also affects the electron cloud distribution of the naphthalene ring. Triethyl methyl is an electron supply group, which can increase the electron cloud density of the naphthalene ring and enhance the electrophilic substitution reaction activity of the naphthalene ring. At the same time, the steric hindrance effect of triethyl methyl cannot be underestimated. During the reaction, the steric hindrance may affect the proximity of the reagent to the reaction check point, especially in the reaction involving larger volumes of reagents, or change the reaction selectivity, and tend to react where Overall, 2-% cyanotriethyl naphthalene exhibits unique chemical properties due to the cyano group activity, the aromaticity of naphthalene ring, and the electronic and spatial effects of triethyl methyl, which hold many potential reaction paths and applications in the field of organic synthetic chemistry.
What are the preparation methods of 2-chloro (trifluoromethyl) benzene?
To prepare 2-chloro (triethylmethyl) benzene, the following ancient methods can be used.
First, benzene is used as the starting point, and the halogenated hydrocarbon is first reacted with the help of a catalyst. The halogenated hydrocarbon is selected from triethylmethyl halide, and the catalyst is commonly used anhydrous aluminum trichloride. This reaction is a Fu-gram alkylation reaction. The process is as follows: Under the action of the catalyst, the halogenated hydrocarbon generates a carbocation ion. This carbocation ion is electrophilic and will attack the electron cloud of the benzene ring, causing the hydrogen on the benzene ring to be replaced, resulting in 2-chloro (triethylmethyl) benzene. However, this reaction should be noted. Because the alkyl group has an electron-pushing effect, it will make the product benz In order to control side reactions, excessive benzene can be made, halogenated hydrocarbons can be fully reacted, and polyalkylation products can be reduced.
Second, benzene can be acylated first. The acylation product is obtained by reacting triethylmethylhalide with benzene under the catalysis of anhydrous aluminum trichloride. This reaction can effectively avoid multi-substitution side reactions. Because the acyl group is an electron-withdrawing group, it will reduce the electron cloud density of the benzene ring, so that the product is no longer easy to react with electrophilic reagents. Then the acylation product is reduced, and the zinc amalgam and concentrated hydrochloric acid are used as reducing agents. After the Clemson reduction reaction, the carbonyl group is reduced to methylene, and then 2-chloro (triethylmethyl) benzene is obtained
Third, the Grignard reagent method can also be used. First, the Grignard reagent is prepared from halogenated benzene, such as the Grignard reagent is obtained by reacting 2-chlorobromobenzene with magnesium in anhydrous ether. Then the Grignard reagent is reacted with triethylmethyl halide to obtain the target product 2-chloro (triethylmethyl) benzene. This process needs to be carried out in an anhydrous and anaerobic environment. Because the Grignard reagent is extremely active, it will react quickly in contact with water or oxygen and fail.
All the above production methods have advantages and disadvantages. In actual operation, it is necessary to comprehensively consider many factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product. Choose the appropriate one and use it.
What are the precautions for using 2-chloro (trifluoromethyl) benzene?
2-% (triethylmethyl) silicon is a rare thing. When it is used, it is necessary to pay attention to all kinds of things in order to ensure its effectiveness and safety.
First, this silicon is easy to be oxidized. In case of sulfuric acid and nitric acid, it will immediately cause a strong reaction, or the danger of explosion. Therefore, when it is used, it must be oxidized. It must be placed in a dry and well-connected place, and it should be protected by inertness.
Second, 2-% (triethylmethyl) silicon is sensitive to moisture. If the temperature in the air is slightly higher, it is easy to evaporate and cause the reaction of hydrolysis, causing it to break down and reduce its performance. To use it, it needs to be operated in a dry environment, or in a glove box, and the equipment involved is fully dry, and no water vapor can be retained.
Third, because it has a certain resistance, and steaming or micro-toxicity. The use of the product must be guaranteed to be good, in order to prevent steaming and accumulation, harm to the body. If the product can be used, it is advisable to use a row operation, and the operator should also wear appropriate anti-staining equipment, such as gas masks, anti-staining gloves, etc., for their own safety.
Fourth, 2-% (triethylmethyl) silicon part gold or its compounds can also react. Such as gold, gold, or accelerate its decomposition. In the case of anti-phase equipment used in reverse containers, it is necessary to avoid using this gold material, and inert materials such as glass and polytetrafluoroethylene can be used to avoid accidents.

For the use of 2-% (triethylmethyl) silicon, it is necessary to follow the above procedures carefully before it can be used.