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2-Chloro-6-Fluorotoluene

2-Chloro-6-Fluorotoluene

Hongda Chemical

Specifications

HS Code

897350

Chemical Formula C7H6ClF
Molar Mass 146.573 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 157 - 159 °C
Density 1.186 g/cm³ (estimated for similar halo - toluenes)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
Vapor Pressure Low vapor pressure at room temperature
Flash Point Around 50 °C (estimated for halogenated aromatic hydrocarbons)

As an accredited 2-Chloro-6-Fluorotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle packaging for 2 - chloro - 6 - fluorotoluene chemical.
Storage 2 - Chloro - 6 - fluorotoluene should be stored in a cool, well - ventilated area away from heat and ignition sources. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Given its flammability and potential toxicity, ensure proper labeling and restricted access in a storage facility compliant with safety regulations.
Shipping 2 - chloro - 6 - fluorotoluene is shipped in well - sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, with proper labeling indicating its nature and handling precautions to ensure safe transportation.
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2-Chloro-6-Fluorotoluene 2-Chloro-6-Fluorotoluene
General Information
Historical Development
The beginning of 2-chloro-6-fluorotoluene, although it is difficult to study in detail at the beginning of ancient times. However, since modern times, the technology of chemistry has advanced day by day, and various explorations have been made.
In the past, chemists devoted themselves to the study of organic synthesis, and devoted themselves to the ratio of compounds and the conditions of reaction. After exhaustive trials, this method of preparing 2-chloro-6-fluorotoluene was obtained. At the beginning, its preparation was cumbersome and the yield was not high, but scholars were determined and made unremitting improvements.
From the simple means of the past to the refinement of today's technology. The reaction equipment is becoming more and more sophisticated, and the control of conditions is becoming more and more accurate, resulting in an increase in the output of 2-chloro-6-fluorotoluene and excellent quality. Looking at its historical evolution, it is the cohesion of chemical researchers, which has promoted the wider application of this substance in chemical and other fields, and the future is also more and more bright.
Product Overview
2-Chloro-6-fluorotoluene is an organic compound. It may be a colorless liquid with a special odor. This compound is widely used in the field of organic synthesis.
Looking at its structure, chlorine and fluorine atoms are connected to the benzene ring of toluene, and the position is specific. Chlorine occupies two positions and fluorine is at six positions, which makes it unique in chemical properties. Because it contains halogen atoms, it has some properties of halogenated hydrocarbons and can participate in many nucleophilic substitution reactions.
In industrial preparation, it is often obtained through a specific chemical reaction path. With suitable raw materials and a series of steps such as halogenation, the purpose of preparation can be achieved. It is often used as a key intermediate in the fine chemical industry such as medicine and pesticides. It can provide an important structural foundation for the creation of new drugs and high-efficiency pesticides, and help the development of related industries.
Physical & Chemical Properties
2-Chloro-6-fluorotoluene is also an organic compound. Its physical and chemical properties are quite specific. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is moderate, which is conducive to separation and purification. As for chemical properties, due to the presence of chlorine and fluorine atoms, its chemical activity is unique. Chlorine atoms have certain nucleophilic substitution activity, while fluorine atoms enhance the stability and electronegativity of molecules. The synergy between the two makes 2-chloro-6-fluorotoluene a key intermediate in organic synthesis. Due to its unique physical and chemical properties, it has a wide range of application prospects in the fields of medicine, pesticides, etc., and can participate in the construction of a variety of complex organic compounds, which is important for chemical research and industrial production.
Technical Specifications & Labeling
Today, there is 2-chloro-6-fluorotoluene. In the field of chemical industry, its technical procedures and identification (product parameters) are very important. To make this substance, you must follow a subtle method. First take an appropriate amount of raw materials, mix them according to a specific ratio, and under a suitable temperature and pressure environment, with the help of catalysts, so that the reaction can be carried out in an orderly manner.
As for the identification (product parameters), its color is pure, or colorless and transparent, with a specific boiling point and melting point, and it is accurately determined to show its properties. Purity is also the key, and it must meet high standards, and the impurity content is minimal. In this way, 2-chloro-6-fluorotoluene meets the needs of industrial applications to develop its effectiveness in various fields.
Preparation Method
The method of making 2-chloro-6-fluorotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw material is often toluene-based, supplemented by chlorine and fluorine-containing reagents.
The production process first reacts toluene with chlorine reagents under specific conditions to introduce chlorine atoms. This step requires controlling the temperature, pressure and reaction time to ensure that the reaction is moderate and avoids side reactions. After adding fluorine reagents, through substitution reaction, to form 2-chloro-6-fluorotoluene.
The first step is chlorination. Under the catalysis of a catalyst such as an iron salt, toluene and chlorine react at a suitable temperature to obtain a chlorine-containing intermediate. The second is fluorination, and the intermediate reacts with the fluorine reagent under the action of a specific solvent and catalyst to achieve the purpose of substitution.
Catalytic mechanism, catalysts such as iron salts can reduce the activation energy of the reaction, and promote effective substitution of chlorine and fluorine atoms. And in the reaction process, precise control of conditions makes the reaction move towards the generation of 2-chloro-6-fluorotoluene, with the key to yield and purity.
Chemical Reactions & Modifications
2-Chloro-6-fluorotoluene is also an organic compound. Its chemical reaction and modification are important for our research.
Looking at this compound, the substitution of chlorine and fluorine on the benzene ring affects its chemical properties. Chlorine atoms are electron-absorbing, and so are fluorine atoms. The two cooperate to change the electron cloud density of the benzene ring, so that its electrophilic substitution reactivity is different.
To change its properties, nucleophilic substitution can be applied. With appropriate nucleophilic reagents, it can be easily substituted with 2-chloro-6-fluorotoluene to obtain new compounds. For example, alkoxy-containing products can be obtained as nucleophiles to expand their applications.
Or in the context of catalysis, 2-chloro-6-fluorotoluene can participate in the coupling reaction, linking different groups, increasing its structural complexity and function, and is a new material for materials, drugs, etc. This is the way of chemical modification.
Synonyms & Product Names
2-Chloro-6-fluorotoluene is also a chemical substance. It is the same as the trade name, the gist of the product. It is the same, or it may be used to express its properties and manufacture. The trade name is due to the needs of the business, and each has its own characteristics.
2-chloro-6-fluorotoluene, or chloro-fluorotoluene, which is named after its position in the phase of chlorine and fluorine atoms on the benzene. In the business, it may be named under the name of special, hoping that the city will recognize it. For example, a merchant uses the trade name of "refined chlorofluorobenzene" to express its high reputation.
All the same trade names are used for research, commerce, and circulation. To help the workers clearly identify this thing, and to conduct research and transactions as soon as possible.
Safety & Operational Standards
Specifications for the safety and operation of 2-chloro-6-fluorotoluene
For 2-chloro-6-fluorotoluene, it is also common for chemical preparation. To investigate its safety and operation regulations, please review all matters in detail.
#1. Storage requirements
This substance should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Its container must be tightly sealed to prevent moisture and air from entering. Cover 2-chloro-6-fluorotoluene in case of moisture, heat or long-term contact with air, or cause qualitative change, increasing the risk of danger. And should not be stored in one place with strong oxidants, strong alkalis, etc., to prevent their chemical reactions and produce violent changes.
#2. Rules of Operation
When operating, appropriate protective equipment must be worn. Such as anti-goggles, which can protect the eyes from splashing; gas masks, which can prevent their gas from entering the body; chemical-resistant gloves and protective clothing, which can prevent them from coming into contact with the skin. The ventilation between the operations must be smooth, so that the volatile gas can dissipate quickly and avoid accumulation. When taking it, the action should be slow and careful to avoid spillage. If there is any spillage, cover it with inert materials such as sand and vermiculite as soon as possible, put it in an airtight container, and dispose of it according to regulations. Do not let it flow and stain the ground.
#3. Emergency measures
If you accidentally touch the skin, quickly rinse with a lot of water, followed by fine washing with soap. If it enters the eye, quickly open the eyelids, rinse with flowing water or normal saline, and seek medical attention as soon as possible. If you inhale its gas, quickly leave the scene to a place with fresh air, lie down and rest slowly. If you have difficulty breathing, apply artificial respiration and seek medical treatment urgently. In case of fire, it is advisable to use dry powder or carbon dioxide fire extinguisher to put it out. Do not use water, because it is insoluble in water, and the pouring of water may cause the fire to spread.
All operations involving 2-chloro-6-fluorotoluene should strictly abide by these safety and operation regulations to ensure personal safety, protect the environment, and avoid accidents.
Application Area
2-Chloro-6-fluorotoluene is also an organic compound. Its application field is quite extensive. In the field of pharmaceutical chemistry, it can be used as a key intermediate to help create new special drugs to cure various diseases. In the field of materials science, it can also play an important role, or can optimize the performance of materials to make them more durable. And in the fine chemical industry, this compound can be used to prepare high-end fine chemicals to improve the quality and value of products. Therefore, 2-chloro-6-fluorotoluene plays an indispensable role in many fields and contributes significantly to the development of various industries.
Research & Development
Modern chemistry has flourished, studying the properties of substances and seeking the reason of creation. Today there is a thing named 2-Chloro-6-Fluorotoluene, and our generation has studied it in detail.
Begin to investigate its structure. Chlorine and fluorine are accompanied by benzene ring and methyl group, and the structure is unique. This is the basis for research. Then study its properties, in the reaction, observe its activity, measure its degree of melting, know its chemical properties, and physical characteristics.
If you want to develop, you must find a new method of synthesis. Improve the old technique, save its steps, improve its yield, and reduce its cost. And explore its application field, which may be of great use in medicine and materials.
We should study diligently and use scientific methods to seek the development of this material, hoping to gain new things, and do our best for the progress of chemistry.
Toxicity Research
Detailed observation of material properties is related to the safety of life and people. Now on 2 - Chloro - 6 - Fluorotoluene, the study of its toxicity cannot be ignored.
Detailed examination of its quality, in various experiments, gradually understand its nature. If you accidentally touch it, or into the skin, or through breathing, it can cause harm. In the organs of the body, it can disturb its work. The qi of the lungs may be messed up because of it; the transportation of the liver and spleen may also be hindered by it.
And looking at it in the environment, it is not good. Entering the water and soil can pollute it and harm all living things. When insects encounter them, their vitality may be at risk; when plants and trees meet them, they will grow and wither or change.
Therefore, to study its toxicity, we must be cautious. It is the right way to establish regulations to prevent its escape, to ensure the safety of the people, and to protect the clearness of heaven and earth. I hope that our generation will be unremitting, and we will study the nature of things, so as to eliminate poisons and diseases, so that all people in the world can be at peace and all things can be at peace.
Future Prospects
Today there is a product called 2-chloro-6-fluorotoluene. Looking at this product, its unique nature, wide range of uses, and infinite potential in the field of chemical industry.
Although it is used or not widely used today, my heart is looking to the future, and I believe it will have great development. Think of the progress of industry and the rise of science and technology, all rely on new things to promote it. 2-chloro-6-fluorotoluene has a special structure, which may open up new paths for the production of new materials and the research of new drugs.
In the future world, or see it in the field of electronics and medicine, emerging. Electronic devices are more refined and smaller, making medical prescriptions more effective. Our scientific researchers, when diligently researching, exploring its secrets, and exploring its uses, hope to be able to pave the way in the undeveloped road, so that 2-chloro-6-fluorotoluene blooms and is used by the world.
Where to Buy 2-Chloro-6-Fluorotoluene in China?
As a trusted 2-Chloro-6-Fluorotoluene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chloro-6-Fluorotoluene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Chloro-6-Fluorotoluene?
2-Chloro-6-fluorotoluene is also an organic compound. It has a wide range of uses and is involved in various fields of chemical industry.
First, it can be used as a raw material for pharmaceutical synthesis. In the process of pharmaceutical preparation, based on this, through various reactions, a variety of specific drugs can be prepared. For example, in the preparation of antibacterial and antiviral drugs, 2-chloro-6-fluorotoluene can be a key intermediate when the molecular structure is constructed. Through precise chemical reactions, its structure is gradually derived to eventually form a drug molecule with specific pharmacological activity.
Second, it also has important functions in the field of pesticides. It is an important component for the synthesis of new and efficient pesticides. Modern pesticides pursue high efficiency, low toxicity and environmental friendliness. 2-chloro-6-fluorotoluene participates in the synthesis of pesticides, which can have strong inhibitory and killing effects on specific pests and pathogens. With its special chemical structure, it can interact with specific biomolecules in pests and pathogens, interfere with their normal physiological metabolism, and achieve the purpose of prevention and control.
Furthermore, in the field of materials science, it is also an important starting material for the synthesis of special materials. It can be introduced into the structure of polymer materials through polymerization reactions, etc., giving the material special properties. Such as enhancing the chemical resistance and heat resistance of the material. The material can still retain good physical and chemical properties in special environments and broaden the application range of materials.
In addition, it is also indispensable in the preparation of fine chemical products. Such as for the synthesis of special flavors, dyes and other additives. With its unique chemical properties, it imparts a unique aroma or color to the product, enhancing the quality and added value of the product. In short, 2-chloro-6-fluorotoluene, with its special molecular structure, plays a key role in many chemical fields, promoting technological progress and product innovation in various fields.
What are the physical properties of 2-Chloro-6-Fluorotoluene?
2-Chloro-6-fluorotoluene is an organic compound with specific physical properties. Its properties are colorless to light yellow liquid. This color state is common in organic compounds, due to molecular structure and electronic transition characteristics.
The boiling point is about 150-152 ° C. The boiling point is affected by intermolecular forces. The molecule of 2-chloro-6-fluorotoluene contains chlorine and fluorine atoms. Its electronegativity causes strong intermolecular forces, so the boiling point reaches this range.
The melting point is about -50 ° C, which is relatively low. Although there is a certain force between molecules, it is not enough to be closely arranged as a solid state at room temperature, and only solidifies at low temperatures.
The density is about 1.18 - 1.20 g/cm ³, which is slightly heavier than water. This is due to the type and number of atoms in the molecule, and the specific structure of carbon, hydrogen, chlorine, and fluorine atoms determines their mass and volume ratio, so that the density is in this range.
It is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, acetone, etc. This is due to the principle of "similarity and miscibility". 2-chloro-6-fluorotoluene is a non-polar or weakly polar molecule, and water is a polar molecule. The polarity of the two is very different and insoluble. Organic solvents are mostly non-polar or weakly polar, which is similar to the polarity of 2-chloro-6-fluorotoluene, so they are soluble.
In addition, 2-chloro-6-fluorotoluene is volatile to a certain extent. At room temperature and pressure, some molecules gain enough energy to escape from the liquid surface, causing it to have an odor. The volatility requires specific conditions for storage and use to ensure safety and stability.
Is 2-Chloro-6-Fluorotoluene chemically stable?
2-Chloro-6-fluorotoluene is also an organic compound. The stability of its chemical properties should be investigated in detail.
In this compound, the existence of chlorine and fluorine atoms has a great influence on its properties. Chlorine atoms have certain electronegativity, which can change the distribution of molecular electron clouds, and so do fluorine atoms, and fluorine is particularly electronegative. The two are co-located on the benzene ring of toluene, causing the electron cloud density of the benzene ring to change, and show unique activity in chemical processes such as electrophilic substitution reactions.
However, in terms of its stability, it is relatively stable at room temperature and pressure without the action of special chemical reagents. The conjugated system of benzene ring endows it with certain stability, and the existence of methyl groups also affects the intermolecular forces to a certain extent, further affecting its chemical activity. However, when encountering specific chemical environments such as strong oxidants, strong acids or strong bases, its stability is challenged. Strong oxidants can cause oxidation reactions of benzene rings or side chains, and strong acids and strong bases may cause reactions such as substitution and elimination, which may change its structure and properties.
If under conditions such as light or heating, the molecular energy increases, the reactivity also increases, and the stability decreases, which may lead to various chemical changes such as free radical reactions.
Therefore, the chemical properties of 2-chloro-6-fluorotoluene are relatively stable at room temperature and pressure without special reagents, but under specific chemical environments and conditions, the stability is easily broken, showing rich chemical reactivity.
What is the production process of 2-Chloro-6-Fluorotoluene?
2-Chloro-6-fluorotoluene is also an organic compound. Its preparation process is related to the delicacy of chemistry, let me explain in detail.
It is often obtained from a specific starting material through a multi-step chemical reaction. At first, choose the appropriate toluene derivative, which is the foundation. Toluene, a genus of aromatic hydrocarbons, has special chemical activity.
Introduce fluorine atoms at a specific position of toluene before this step or use the method of fluoridation. With suitable fluorination reagents, under specific reaction conditions, fluorine atoms are cleverly replaced by hydrogen atoms. Reaction conditions such as temperature, pressure, catalyst, etc., all need to be precisely controlled. If the temperature is too high or the side reactions are clustered, if it is too low, the reaction will be slow or even stagnant.
Then chlorine atoms are introduced. The introduction of chlorine atoms also has its own method. Or use chlorination reagents, under another reaction condition, the chlorine atoms are placed in a predetermined position, adjacent to the fluorine atoms. The key to chlorination reaction also lies in the determination of conditions, and attention must be paid to the order of introduction. Due to different introduction orders, the products may be different.
The whole preparation process is like a delicate chess game. If you make one wrong step, you will lose everything. After each step of the reaction, you need to separate and purify to remove impurities and obtain a pure product. Separation or distillation, extraction, etc. are selected according to the physical and chemical properties of the product and impurities.
After purification, it is carefully tested to verify its purity and structure to ensure that the obtained product is 2-chloro-6-fluorotoluene. In this process, the interlocking process requires the wisdom and patience of chemists to prepare this organic compound.
What are the precautions in storage and transportation of 2-Chloro-6-Fluorotoluene?
2-Chloro-6-fluorotoluene is an organic chemical. When storing and transporting, special attention should be paid to the following things:
First, when storing, be sure to choose a dry, cool and well-ventilated place. Because of its volatility, if placed in a high temperature or humid place, the volatilization will increase, or it will react with water vapor, causing quality changes. And good ventilation can avoid its accumulation in the space, reducing the risk of explosion and poisoning.
Second, this substance has high packaging requirements. A tightly sealed container must be used to prevent leakage. Glass containers or special plastic containers are commonly used, but the glass is fragile, so be careful when handling; plastic containers should be selected that can withstand its corrosion.
Third, the storage environment temperature must also be strictly controlled. It should not be too high, otherwise it is easy to accelerate volatilization and decomposition; nor too low, so as not to cause solidification of substances and affect the use and subsequent use. Generally, it should be controlled in a specific temperature range, which should be determined according to its physical and chemical properties and relevant standards.
Fourth, during transportation, ensure that the container is stable and prevent package damage caused by collision and vibration. Transportation vehicles should also be equipped with corresponding fire and leakage emergency treatment equipment. And transport personnel must be professionally trained and familiar with the characteristics of the substance and emergency response methods.
Fifth, 2-chloro-6-fluorotoluene may be toxic and irritating. Clear warning signs should be set up in the storage and transportation areas, and unrelated personnel should not be allowed to approach. If there is a leak, take effective measures quickly, such as evacuating people, containing the leak, adsorbing with suitable materials, etc., and report it to the relevant departments in a timely manner.
In general, there are strict requirements for the storage and transportation of 2-chloro-6-fluorotoluene, from the environment, packaging to personnel operation, etc., so as to ensure safety and avoid accidents.