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2-Chloro-5-Trifluoromethyl Bromobenzene

2-Chloro-5-Trifluoromethyl Bromobenzene

Hongda Chemical

Specifications

HS Code

583154

Chemical Formula C7H3BrClF3
Molecular Weight 273.45
Appearance Colorless to light yellow liquid
Boiling Point Around 185 - 190°C
Density Typically around 1.7 - 1.8 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ether, benzene
Flash Point Around 75 - 85°C
Vapor Pressure Low vapor pressure at room temperature
Stability Stable under normal conditions but reactive with strong oxidizing agents

As an accredited 2-Chloro-5-Trifluoromethyl Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - chloro - 5 - trifluoromethyl Bromobenzene in a sealed glass bottle.
Storage 2 - chloro - 5 - trifluoromethyl bromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive substances to prevent potential chemical reactions. Label the storage container clearly.
Shipping 2 - chloro - 5 - trifluoromethyl Bromobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling and documentation to ensure safe transport.
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2-Chloro-5-Trifluoromethyl Bromobenzene 2-Chloro-5-Trifluoromethyl Bromobenzene
General Information
Historical Development
2-Chloro-5-trifluoromethyl bromobenzene is also an organic chemical. Its origin can be traced back to the beginning of chemical exploration in the past. At that time, all the sages studied diligently in the field of organic synthesis, hoping to gain something.
At the beginning, the understanding of halogen-containing organic compounds was still shallow, but scholars were determined. After years of trial and error, the reaction mechanism was gradually understood. At a certain time, a wise person, under specific experimental conditions, made this prototype for the first time in an exquisite way. Although the process was not perfect at that time and the yield was low, this was an important beginning.
In the following years, chemists continued to improve the synthesis path. The proportion of reactants may be changed, the temperature and duration of the reaction may be adjusted, or new catalysts may be explored. After many efforts, the process has improved and the yield has gradually increased. 2-chloro-5-trifluoromethyl bromobenzene has emerged in the field of organic synthesis, laying the foundation for many subsequent organic reactions and compound preparation, and opening a new chapter in organic chemistry.
Product Overview
2-Chloro-5-trifluoromethyl bromobenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis and is often a key intermediate for the preparation of many complex organic molecules.
Looking at its structure, chlorine atoms and bromine atoms are connected to the benzene ring, and trifluoromethyl is also in a specific position. This unique structure gives it special chemical properties. In chemical reactions, chlorine and bromine atoms can participate in nucleophilic substitution reactions, providing an opportunity for the introduction of other functional groups. The existence of trifluoromethyl significantly affects the electron cloud distribution and spatial structure of the molecule, which in turn affects the stability, solubility and reactivity of the compound.
In the chemical industry, 2-chloro-5-trifluoromethylbromobenzene is often used in the synthesis process of medicine, pesticide and material science. Due to its special structure, through rational design of reaction routes, substances with specific biological activities or functions can be prepared, providing an important basis for the development of related industries.
Physical & Chemical Properties
2 - Chloro - 5 - Trifluoromethyl Bromobenzene is an important chemical substance. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. It has a higher density than water and is insoluble in water, but it can be miscible with most organic solvents. The boiling point is within a certain range, which is related to its intermolecular forces.
When it comes to chemical properties, bromine and chlorine atoms in this substance are active and can participate in a variety of substitution reactions. Because it contains trifluoromethyl, the molecule has unique electronic and spatial effects. In the field of organic synthesis, it is often used as a key intermediate to build complex organic molecular structures through various reactions, which can help the research and development of new drugs and materials.
Technical Specifications & Labeling
There are chemical products today, the name is 2-chloro-5-trifluoromethyl bromobenzene. Its process specifications and identification (product parameters) are the key.
The process specification is the criterion for the preparation of this product. From the selection of raw materials, it is necessary to carefully select, and the impurities must be minimal to ensure the purity of the product. To the reaction conditions, temperature and pressure must be precisely controlled, with a millimeter difference or very different quality. The reaction time cannot be ignored. If it is too long or too short, it will affect the quality of the finished product.
In terms of identification (product parameters), the purity should be clearly marked, which is an important indicator to measure the quality of the product. Appearance properties should also be clearly described. Whether it is a colorless and transparent liquid, or a slight color, is related to quality. Other parameters, such as boiling point, melting point, etc., should not be omitted for users to properly apply according to their characteristics. In this way, the process specification and identification (product parameters) complement each other to obtain high-quality 2-chloro-5-trifluoromethylbromobenzene.
Preparation Method
The method of making 2-chloro-5-trifluoromethyl bromobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism, which are described in detail as follows.
First take an appropriate amount of halogenated aromatics as raw materials, which need to be pure and free of impurities. Co-placed with fluorinated reagents in a special reactor, which needs to be able to withstand specific temperatures and pressures. Adjust the temperature to a suitable range, about tens of degrees Celsius, and precisely control the pressure to create a good reaction environment.
The reaction steps are rigorous and orderly. The halogenated aromatics and fluorinated reagents are slowly mixed first, and the molecules collide and interact with each other. Introducing a high-efficiency catalyst, this agent can significantly reduce the activation energy of the reaction and speed up the reaction The catalyst is carefully screened according to the reaction characteristics, and the dosage is also accurately calculated.
During the reaction process, the reaction process is closely monitored, and modern analytical methods, such as chromatographic analysis, are used to ensure that the reaction proceeds in the expected direction. When the reaction reaches a specific level, through a series of post-processing processes, such as purification and separation, pure 2-chloro-5-trifluoromethylbromobenzene products can be obtained. In this way, careful control of each link is paid attention to in order to produce high-quality products efficiently.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance named 2-chloro-5-trifluoromethyl bromobenzene, which has a lot to study in chemical reactions and properties.
Looking at its chemical structure, halogen atoms coexist, and chlorine, bromine and trifluoromethyl coexist in a benzene ring. This unique structure makes it specific in chemical reactions.
In terms of reactivity, the halogen atoms on the benzene ring have uneven electron cloud density distribution due to electronegativity differences. Chlorine and bromine atoms can cause the density of adjacent and para-position electron clouds to increase relatively, which is easy to attract electrophilic reagents to attack. However, trifluoromethyl has strong electron absorption, which decreases the overall electron cloud density of the benzene ring, and the change of reactivity is really intriguing.
Furthermore, its properties also vary with structure. The introduction of trifluoromethyl increases its lipid solubility, and it may have other applications in organic synthesis and materials. After various experiments, it can be seen that its reaction path under different reaction conditions, and then improve it, and seek better reaction effect and product performance, which will contribute to the development of chemistry.
Synonyms & Product Names
2-Chloro-5-trifluoromethyl bromobenzene, this substance is quite important in our chemical research. Its synonymous name and trade name also need to be carefully studied.
The names of the husband are all different names of this substance, but the meaning is the same. Or according to its chemical structure characteristics, or according to past research practices, many synonymous names are obtained. As for the trade name, it is related to business operation and market identification. Different merchants either give them unique trade names to highlight their product characteristics or based on brand construction.
It is essential for our chemical researchers to clarify the synonyms and trade names of 2-chloro-5-trifluoromethylbromobenzene when exploring the properties, uses and reaction mechanisms of 2-chloro-5-trifluoromethylbromobenzene. One can avoid misunderstandings in communication, and the other can comprehensively cover relevant information during literature search and market survey. In this way, we can gain deeper insights into this substance and pave a smooth path for chemical research and practical application.
Safety & Operational Standards
2-Chloro-5-trifluoromethyl bromobenzene is a common chemical in chemical research. Safety and handling practices are of paramount importance during its use and research.
For storage, choose a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent them from being dangerous due to heat. This product should be stored separately from oxidizing agents and bases, and must not be mixed. It is dangerous due to the interaction of different chemicals or severe reactions.
When operating, the experimenter must wear appropriate protective equipment. Protective glasses must be able to effectively block liquids that may splash and prevent damage to the eyes; protective gloves should be chemically resistant to avoid contact with the skin. The operation should be carried out in a fume hood to ensure air circulation, timely discharge of harmful gases that may be volatilized, and ensure the safety of the experimenter's breathing.
If you accidentally come into contact with this chemical, you should take corresponding measures immediately. If it touches the skin, rinse with a large amount of flowing water immediately for not less than 15 minutes, and then seek medical attention according to the situation; if it splashes into the eyes, you must also rinse with a large amount of water immediately, and rotate the eyeball at the same time to completely remove it, and then seek medical attention as soon as possible.
When using this chemical for reaction, it is necessary to precisely control the reaction conditions. Temperature, pressure, ratio of reactants, etc. are all related to the process and safety of the reaction. Do not rashly change the established reaction parameters to prevent accidents.
Furthermore, the experimental site should be equipped with corresponding emergency treatment equipment, such as fire extinguishers, eye washers, first aid medicines, etc. In the event of an accident, rescue can be carried out in time to minimize losses.
In short, in the research and use of 2-chloro-5-trifluoromethylbromobenzene, strict adherence to safety and operating standards is fundamental to ensure personnel safety and the smooth progress of the experiment.
Application Area
2-Chloro-5-trifluoromethyl bromobenzene is also a new product. Its application field is quite vast. In the field of medicine, it can be a key raw material for the synthesis of special drugs. With its unique chemical structure, it can participate in many delicate reactions, resulting in drugs with excellent curative effects on specific diseases.
It is also useful in pesticides. It can be transformed into a series of highly efficient and low-toxic pesticide ingredients, which help to prevent insects and protect seedlings and maintain the abundance of crops.
In the field of materials science, it can be used as the cornerstone of functional material synthesis. Make the material obtain special properties, such as excellent weather resistance and stability.
With its unique quality, this product has developed its strengths in many fields, adding help to the chemical, pharmaceutical, agricultural planting, materials and other industries, with promising prospects.
Research & Development
Modern chemistry has advanced, and new substances have emerged one after another. 2 - Chloro - 5 - Trifluoromethyl Bromobenzene is gradually becoming more and more important in various fields of chemistry.
Our research began to explore its properties. Its structure is exquisite, containing chlorine, fluorine, and bromine atoms, resulting in its unique physicochemical properties. At first, the synthesis method was not good, and the yield was quite low. However, many colleagues have worked tirelessly, and the process has been improved over the years, and the yield has gradually increased.
Looking at its use today, it can be used in pharmaceutical synthesis, and can be used as a key intermediate to help create new drugs, which is expected to solve the difficulties of many diseases. In the field of materials, it has also emerged, or contributed to the development of new materials. Looking to the future, with the deepening of research, its development will be even broader, contributing to the progress of chemistry and the well-being of mankind.
Toxicity Research
There is a chemical substance today, named "2 - Chloro - 5 - Trifluoromethyl Bromobenzene". As a chemical researcher, it is very important to detect its toxicity. This substance has a special structure and contains atoms such as chlorine, fluorine, and bromine, or it may be potentially toxic.
After experiments, it was tested in mice. Feed it with an appropriate amount of the substance and observe its appearance regularly. Not long ago, the behavior of the mice was slightly different, and the diet was reduced. According to the dissection, the organs were slightly damaged. From this, this "2 - Chloro - 5 - Trifluoromethyl Bromobenzene" has a certain toxicity. However, in order to understand its toxicology and toxic effects in detail, it is necessary to study more methods, increase the number of samples, and investigate its mechanism of action in order to clarify its impact on organisms and the environment, so as to provide evidence for protection and application.
Future Prospects
Fu 2-chloro-5-trifluoromethyl bromobenzene is also an organic compound. In today's chemical research, this substance has gradually become more and more important. Its unique structure, with chlorine, bromine and trifluoromethyl groups, has specific properties, and has unlimited possibilities for various applications.
Looking at the future, it can be a key intermediary in the creation of medicine. With its special structure, it can precisely interact with biomolecules, help the development of new drugs, cure various diseases, and seek well-being for the health of all beings. In material science, or give new energy to materials, make high-performance special materials, which can be used in aerospace, electronics and other fields to promote the advancement of science and technology.
We chemical researchers should do our best to explore its mysteries and explore its uses. With unremitting research, we hope to make this compound shine in the future and benefit the world. This is also our vision for the future.
Where to Buy 2-Chloro-5-Trifluoromethyl Bromobenzene in China?
As a trusted 2-Chloro-5-Trifluoromethyl Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chloro-5-Trifluoromethyl Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2-chloro-5-trifluoromethylbromobenzene?
2-% -5-triethylnaphthalene, this material has a general physical property. Its outer surface is often crystalline, and it can be observed that its crystal shape is complete, and it has a specific shape.
As far as melting is concerned, melting has characteristics, and it needs to be melted at a specific degree. This degree must be [X] ° C, and the boiling value is also a specific value, and it can only be boiled at [Y] ° C. Such melting characteristics make it appear different physical properties under different temperature environments, and it is difficult to remain stable under normal conditions.
Its density is also fixed, and the density is [Z] g/cm ³. This value indicates that the amount of its position is the same as that of the substance.
Furthermore, the solubility is also important for physical properties. In some soluble substances, such as ethanol, ether, etc., this substance exhibits a certain solubility and can be partially dissolved in it to form a homogeneous dispersion system. However, in water, its solubility is poor and it is not soluble. This is due to the interaction between molecules and water molecules.
In addition, the light and quality of this substance are also worth noting. In the light environment, if the photometric wave is reduced to a specific level, it may cause the reaction of molecular molecules, etc., resulting in its properties. However, in the high-level environment, beyond a certain degree limit, its transformation or biological modification will affect its physical properties. Therefore, the physical properties of 2-%-5-triethylmethylnaphthalene are of great importance in the fields of chemical industry, materials, and so on.
What are the chemical properties of 2-chloro-5-trifluoromethylbromobenzene?
2-% -5-triethylaminoanisole is a characteristic compound with interesting chemical properties, and it exhibits unique characteristics in the field of diversity.
This compound has the possibility of multiplication and reaction due to its atom-containing activity. The atom can be used in the form of an acid, and it can also be reacted to the original atom, because it has a certain ability to supply particles.
And the triethylamino part, due to the presence of solitary particles on the nitrogen atom, is reactive. This property makes it able to neutralize and react to the acid, forming a phase. At the same time, triethylamino can also be used as a nucleus, such as nuclear substitution, etc. With its rich properties, it can attack the reactive substrate of the missing molecule.
In addition, benzene is aromatic and highly qualitative. However, the density distribution of benzene clouds on benzene is affected by the existence of methoxy triethylamino. Methoxy groups supply the benzene group, which can increase the density of benzene and benzene clouds at the benzene position. Therefore, the benzene of this compound is easy to be substituted and reversed at the local and local locations, such as substitution, nitrification, sulfonation, etc.
In addition, 2-% -5-triethylaminoanisole molecules also interact with different groups, and this interaction also affects their chemical properties. The mutual regulation of the air effect of the benzene group has jointly determined the surface of the chemical reaction of the compound. In the field of synthetic chemistry, it can be used to synthesize more complex compounds by ingenious reverse methods and taking advantage of the characteristics of its various bases.
What are the main uses of 2-chloro-5-trifluoromethylbromobenzene?
2-% -5-triethylmethyl ether naphthalene is an organic compound and the like. It has a wide range of uses and is important in chemical, pharmaceutical and other fields.
In the field of chemical industry, it is often used as an organic solvent. Because of its specific solubility, it can dissolve many organic substances. In the preparation process of coatings and inks, it can help all kinds of ingredients to mix evenly, making the texture of the product more uniform and improving the quality. And its volatility is moderate, and it can achieve ideal results in production operations and product drying.
In the field of medicine, this compound also has extraordinary performance. Or it can be an intermediate for drug synthesis. Through the method of organic synthesis, it can be converted into drug molecules with specific pharmacological activities through a series of chemical reactions. Due to its unique molecular structure, it can introduce specific chemical groups into drug molecules, thereby affecting the activity, solubility and stability of drugs, and helping to develop more efficient and safe drugs.
In addition, in emerging fields such as materials science, 2-% -5-triethylmethyl ether naphthalene is also emerging. Or participate in the synthesis of new materials, endow materials with special properties, such as improving the flexibility and heat resistance of materials, and contribute to the development of materials science. Its use in many fields promotes the progress and development of related industries, and is an indispensable organic compound.
What are the synthesis methods of 2-chloro-5-trifluoromethylbromobenzene?
To prepare 2-cyanogen-5-trifluoromethyl pyridine, there are various methods.
First, the method of cyanidation is based on a suitable pyridine derivative. Choose a pyridine containing a suitable substituent, and under specific reaction conditions, meet with a cyanide reagent. If halogenated pyridine is used as a raw material, the halogen atom has good activity, and can be used with cyanide reagents such as potassium cyanide, etc., under the existence of suitable solvents and catalysts, the nucleophilic substitution reaction is carried out, and the halogen atom is a cyanogroup to obtain the target product. Among them, the choice of solvent is very important, and the solubility of the reactants and products needs to be considered, and it does not have side reactions with cyanide reagents, such as N, N-dimethyl The catalyst may accelerate the reaction and increase the yield.
Second, it is obtained by the construction of pyridine rings. Small molecules containing trifluoromethyl and cyanyl latent functional groups are used as raw materials to build pyridine rings through multi-step reactions. For example, compounds containing carbonyl groups, amino groups and trifluoromethyl groups are used under acidic or basic catalysis to undergo cyclization and condensation reactions. First, the relevant functional groups interact to form a pyridine ring skeleton, and then appropriately modified to introduce cyanyl groups to achieve the purpose of synthesis. This approach is complex, but the selection of raw materials and reaction conditions are carefully controlled, and high-purity products can be obtained.
Third, it is planned by biosynthesis. Find biological enzymes or microorganisms with specific catalytic activities, and synthesize them under mild conditions with suitable substrates. The catalysis of enzymes in biological systems is highly efficient and specific, which can avoid many side reactions in traditional chemical synthesis. However, this biosynthesis method requires finding suitable biocatalysts and optimizing culture conditions to ensure the smooth progress of the reaction, and special consideration is also required for product separation and purification.
All synthesis methods have advantages and disadvantages. In practical application, when the availability of raw materials, cost, product purity and yield are factors, the best selection is carefully considered.
What are the precautions for storing and transporting 2-chloro-5-trifluoromethylbromobenzene?
2-% -5-triethylenyl ether naphthalene, if it is hidden in the dark, please pay attention to the general situation.
The first thing to do is to pay attention to it. This material is flammable, so in the place where it is hidden, it must be a source of fire and energy, and it must be well connected. If it is in a dense and poorly connected place, once it leaks, it can be flammable and gather. In case of open flame or high temperature, it will easily become a fire or even an explosion. Containers that are stored in storage also need to be fixed and well sealed to prevent leakage.
In addition, it may be harmful to them or people. For those who are in hiding, it is necessary to use appropriate anti-leakage measures, such as gas masks, anti-respiratory gloves, etc., to avoid direct contact with the skin and respiratory tract. If it is not accidentally connected, it needs to be washed with a lot of water immediately, and it will be treated according to the symptoms.
And in the process, it is necessary to prepare the relevant fire equipment to deal with the leakage and emergency management. When doing so, those who need to be careful must be careful to avoid the leakage of the container due to bumps and collisions. In addition, there are no clear warnings to prevent leakage in densely populated areas.
In addition, there are no clear warnings to indicate the danger of this thing, so that others can know it at a glance. Regularly check the container to check for any damage or leakage. If there is any problem, it should be dealt with immediately. Therefore, the storage of 2-5-triethylmethylenaphthalene requires all parties to be careful to ensure safety.