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2-Chloro-5-Fluorobromobenzene

2-Chloro-5-Fluorobromobenzene

Hongda Chemical

Specifications

HS Code

299557

Chemical Formula C6H3BrClF
Molar Mass 225.44 g/mol
Appearance Liquid (expected, as it's an organic halide)
Solubility In Water Low, as it's a non - polar organic compound
Solubility In Organic Solvents Good, in solvents like ethanol, ether, etc.

As an accredited 2-Chloro-5-Fluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - chloro - 5 - fluorobromobenzene packaged in a sealed glass bottle.
Storage 2 - chloro - 5 - fluorobromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent ignition. It should be stored in a tightly - sealed container to avoid leakage and contact with air and moisture, which could potentially cause decomposition. Keep it separate from oxidizing agents and reactive chemicals to prevent hazardous reactions.
Shipping 2 - chloro - 5 - fluorobromobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations, ensuring safe handling during transit to prevent leakage and environmental hazards.
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2-Chloro-5-Fluorobromobenzene 2-Chloro-5-Fluorobromobenzene
General Information
Historical Development
2-Chloro-5-fluorobromobenzene is also an organic compound. Tracing back to its origin, chemists in the past studied the techniques of organic synthesis and strived to expand the category of substances. At that time, the exploration of halogenated aromatics was on the rise.
At the beginning, chemists used ingenious methods to manipulate various reaction conditions in the laboratory. After repeated trials and fusion of halogenation techniques, chlorine, fluorine and bromine atoms were cleverly connected to the benzene ring, and finally this compound was obtained.
Its birth did not happen overnight. Since the beginning, it has undergone countless adjustments and improvements. Chemists have changed the ratio of reactants, or the temperature and duration of the reaction, so that the preparation of this compound has gradually improved.
In the development of organic chemistry, the appearance of 2-chloro-5-fluorobromobenzene has paved a new way for subsequent research and application, and has also added a bright color to the field of chemistry.
Product Overview
Description of 2-chloro-5-fluorobromobenzene
Fu2-chloro-5-fluorobromobenzene is also an organic halide. Its molecular structure is exquisite, and the atoms of chlorine, fluorine and bromine occupy specific positions, giving this substance unique properties.
Looking at its physical properties, at room temperature, it is mostly a colorless to light yellow transparent liquid with a special odor. Its physical parameters such as boiling point and melting point also vary depending on the interaction of atoms in the molecule, which is the basis for its separation and purification in the chemical process.
When it comes to chemical properties, it is highly active due to the existence of halogen atoms. It can participate in many nucleophilic substitution reactions, meet with reagents containing active hydrogen, and halogen atoms are easily replaced to form novel compounds. In the field of organic synthesis, it is an important building block for the construction of complex molecular structures.
Furthermore, 2-chloro-5-fluorobromobenzene is also very useful in the creation of medicines and pesticides. With its unique chemical activity, it can develop new drugs and pesticides with high efficiency and low toxicity, making remarkable contributions to human health and agricultural harvest.
Physical & Chemical Properties
2-Chloro-5-fluorobromobenzene is an organic compound. Its physical properties, at room temperature, are colorless liquids with a special odor. Its boiling point is quite high, about 100 degrees of excess, its density is greater than that of water, insoluble in water, but soluble in organic solvents such as alcohols and ethers.
In terms of its chemical properties, it is very active due to halogen atoms. Nucleophilic substitution reactions can occur. If it encounters nucleophilic reagents, halogen atoms are easily replaced by them. And on the aromatic ring, the electron cloud density is uneven, and the adjacent and para-site activities are specific, and it is easy to cause electrophilic substitution reactions.
This compound has a wide range of uses in the field of organic synthesis. It is often used as an important intermediary in the preparation of various pharmaceuticals, pesticides, and fine chemicals, and is particularly crucial in the modern chemical industry.
Technical Specifications & Labeling
2-Chloro-5-fluorobromobenzene, the technical specifications and identification (product parameters) of this compound are the key. Its technical specifications need to be precise and clear, which is related to product quality.
As far as the identification is concerned, the key parameters should be clearly marked. From the perspective of preparation method, a specific process needs to be strictly followed, and the ratio of raw materials and reaction conditions need to be precisely controlled to obtain high-purity 2-chloro-5-fluorobromobenzene. In the identification, the chemical composition and physical properties, such as melting point, boiling point, density and other parameters should be listed in detail for the user to understand. The technical specifications should also cover the limit of impurities to ensure that the product quality is up to standard. In this way, this chemical can be used safely and effectively in various fields, and its due value can be realized.
Preparation Method
2-Chloro-5-fluorobromobenzene is also an organic compound. To make it, the raw materials and processes, the reaction steps, and the catalytic mechanism are all important.
First take fluorobenzene as the starting material, and through the bromination method, coexist with bromine and catalyst, and control the temperature to be suitable to obtain 5-fluorobromobenzene. In this step, select a good catalyst, such as iron halide, to promote the reaction.
Times, 5-fluorobromobenzene is chlorinated again. With a chlorine source, such as chlorine gas, stored in the catalyst, and adjust the reaction environment, 2-chloro-5-fluorobromobenzene can be obtained. The catalytic agent can help the chlorine group to enter the predetermined position and increase the purity of the product.
The reaction step is suitable for precise control of the conditions. Temperature, pressure, and time are all related to the quantity and quality of the product. If the temperature is too high, or there is a side reaction; if the time is too short, the reaction is not complete.
Catalytic mechanism, the catalyst can lower the energy barrier of the reaction, making the molecule easily activated and reaching the reaction state quickly. In this way, following this process, the product of 2-chloro-5-fluorobromobenzene can be obtained.
Chemical Reactions & Modifications
2-Chloro-5-fluorobromobenzene is also an organic compound. In the field of chemistry, its reaction and modification are worth studying.
In the past, to prepare this compound, cumbersome methods were often used. First take the derivative of benzene, through the reaction of halogenation, introduce chlorine, fluorine and bromine atoms. However, this traditional method, the reaction conditions are harsh, and the yield is not perfect.
Today's scholars think about the way to change. By means of catalysis, choose a high-efficiency catalyst to make the reaction conditions mild and increase the yield. In this way, the reaction rate increases and the energy consumption decreases.
Furthermore, the relationship between its structure and properties is also studied in depth. By means of modification, the electron cloud density is adjusted, and the spatial configuration is changed to obtain products with specific properties. This is a new way of chemical research, hoping to use the wonderful reaction and modification to develop the application of 2-chloro-5-fluorobromobenzene in various fields.
Synonyms & Product Names
Today there is a thing called 2 - Chloro - 5 - Fluorobromobenzene. This chemical thing, in our research, has many names. Its aliases, or according to its characteristics and structure.
In the industry, it is often regarded with the same name and different names. Some have different names due to different regions; some have different names due to different research directions. For example, it may be called simply because of its chemical composition, or because of its specific use.
Its trade name, merchants take various names for the convenience of sales and promotion, according to market demand and product positioning. This is to make this thing known and applied to everyone in different situations and fields. Although the names are different, there is no difference in the chemical properties and uses of the same thing.
Safety & Operational Standards
2-Chloro-5-fluorobromobenzene is also a chemical product. Regarding its safety and operating standards, do not be careless.
Preparation of this product must be done in a well-ventilated place. Due to chemical reactions, or the generation of harmful gas, good ventilation can be quickly discharged to avoid harm to the human body. And the experimenter should use protective gear, such as protective clothing, gloves, goggles, etc., to prevent the drug from touching the body and splashing eyes.
When operating, use all kinds of instruments in accordance with regulations. Measure the drug, use a precise device, be sure to use the right amount, never use it. Mixing the agent should also be slow and even, and the reaction state should be observed. If there is any abnormality, it should be disposed of as soon as possible.
Store this substance in a cool and dry place to avoid fire and hot topics. And seal it to prevent it from evaporating or dealing with foreign objects. Mark it clearly, indicating its name, nature and danger, so that it can be used at a glance.
The disposal of waste is also in accordance with regulations. Do not discard it at will to prevent pollution of the environment. Classify and place it for professional treatment.
In short, the safety and operating standards of 2-chloro-5-fluorobromobenzene are of paramount importance to chemical researchers. Only by following the rules can we keep ourselves safe, study smoothly, and be safe from the process of experimentation.
Application Area
2-Chloro-5-fluorobromobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. Through delicate chemical reactions, linked to various active groups, or can create new drugs with excellent efficacy for specific diseases, such as some stubborn inflammation or difficult diseases.
In the field of materials science, this compound may be processed by special processes and integrated into new materials. It can enhance the stability, weather resistance, and even endow materials with unique optical and electrical properties, opening up new avenues for the research and development of high-end materials.
In terms of pesticide chemistry, it may be used as an important raw material for the construction of high-efficiency and low-toxicity pesticides. After rational molecular design and modification, pesticides have high selectivity and strong lethality to target organisms, while reducing the harm to the environment and non-target organisms, which is in line with the needs of today's green agriculture development.
Research & Development
In recent years, Yu dedicated himself to the research of organic compound 2 - Chloro - 5 - Fluorobromobenzene. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path and encountered many difficulties. The ratio of raw materials and reaction conditions are slightly poor, so it is difficult to obtain an ideal product. However, I did not give up. After repeated experiments and detailed study of various factors, a feasible method was finally obtained. The purity of the synthesized product is quite high, in line with expectations.
Then, consider its application and expansion. Exploring in the direction of medicinal chemistry, it was found that it may be used as a key intermediate and participate in the preparation of a variety of specific drugs. Although the road ahead is still long, many details still need to be carved, but the future is promising.
I firmly believe that with time and unremitting research, 2 - Chloro - 5 - Fluorobromobenzene will be able to shine in the field of scientific research and industry, and contribute to the development of related industries.
Toxicity Research
Today there is a substance called 2 - Chloro - 5 - Fluorobromobenzene. I am a chemical researcher, specializing in the study of toxicants, and I will explore the toxicity of this substance in detail.
Looking at its molecular structure, the atoms of chlorine, fluorine and bromine are among them. Chlorine is active, or reacts with various molecules in the body, disrupting its biochemical order. Although fluorine is small, its bond is strong, entering the body or breaking the membrane of the cell, disturbing its metabolism. Bromine is also not a good kind, or causes protein denaturation and enzyme dysfunction.
In fact, I set up various experiments. Take small animals as samples and put this substance in its habitat to observe its behavior and physiological changes. After a while, I saw that its vitality was gradually lost, the diet was sluggish, and even the organs were damaged.
From this point of view, 2-Chloro-5-Fluorobromobenzene is significantly toxic and has serious dangers to the environment and people. When using it in the future, you must be very careful to prevent it from escaping, so as not to kill life and protect the safety of the environment.
Future Prospects
2 - Chloro - 5 - Fluorobromobenzene is also a chemical substance. It has not yet been developed, and there are no possible solutions. This compound has unique properties, or can be used in multiple domains.
In the process of research and development, it may be able to provide contracts for new technologies. Because of its special properties, it may act on specific biological targets, helping to overcome diseases and improve health and well-being.
In the field of materials science, it also has power. It may be able to synthesize high-performance materials and improve the general properties of materials, such as quality and quality, etc., to meet the high requirements of materials that have not been developed in technology.
There may be a bright road ahead, but those who study it must be enthusiastic and willing to explore, hoping to reveal more secrets of it, and promote it in the future, for the benefit of the world.
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Frequently Asked Questions

As a leading 2-Chloro-5-Fluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-Chloro-5-Fluorobromobenzene?
2-Chloro-5-fluorobromobenzene is one of the organic compounds. Its chemical properties are unique and worth exploring.
The first word about its halogenated hydrocarbon properties. Because it contains bromine, chlorine and fluorine halogen atoms, it has a typical reaction of halogenated hydrocarbons. When encountering nucleophiles, halogen atoms can be replaced. If it is co-heated with sodium alcohol, the alkoxy group can substitute halogen atoms to form ether compounds; when reacted with sodium cyanide in an appropriate solvent, the cyanyl group can substitute halogen atoms to obtain nitriles. This nitrile can be hydrolyzed to form carboxylic acids.
Second, the characteristics of the benzene ring also affect its chemical properties. The benzene ring has a conjugated system and is electron-rich Although the halogen atom of 2-chloro-5-fluorobromobenzene is an electron-withdrawing group, the electron cloud density of the benzene ring is slightly reduced, but the benzene ring can still undergo electrophilic substitution reaction. Under the action of appropriate catalysts such as ferric chloride, it can react with bromine, chlorine and other electrophilic reagents to introduce new substituents. Due to the localization effect of halogen atoms, new substituents multiply into specific positions in the benzene ring.
Third, due to the difference in electronegativity of halogen atoms in the molecule, the polarity of molecules is different. This polarity affects its physical properties, and in chemical reactions, it also affects the reactivity and selectivity. For example, in some solvents, the solubility is different, which in turn affects the reaction rate and process.
Fourth, its fluorine-containing atoms give compounds unique properties. Fluorine atoms have extremely high electronegativity and high C-F bond energy, which can enhance molecular stability. In some reactions, fluorine-containing compounds exhibit different reaction paths and products from other halogens.
2-chloro-5-fluorobromobenzene is rich in chemical properties. Halogenated hydrocarbon reactions, phenyl ring electrophilic substitution and fluorine atom properties are the keys to its chemical properties and are of great significance in organic synthesis and other fields.
What are the common synthetic methods of 2-Chloro-5-Fluorobromobenzene?
2-Chloro-5-fluorobromobenzene is also an organic compound. The common synthesis methods have the following numbers.
First, halogenated aromatic hydrocarbons are used as starting materials. You can first take a benzene ring containing a suitable substituent, and introduce chlorine atoms and fluorine atoms through a halogenation reaction. For example, using a benzene derivative as a substrate, under specific reaction conditions, a chlorinated reagent and a fluorinated reagent act on the benzene ring in sequence or simultaneously to achieve the positioning substitution of chlorine and fluorine atoms. During the reaction, attention should be paid to the activity of the reagent, the reaction temperature, the reaction time and the choice of solvent. A suitable solvent can help the reactants to disperse uniformly, promote the progress of the reaction, and also affect the reaction selectivity. If non-protic solvents are used, the effect of some nucleophilic substitution reactions can be enhanced.
Second, through nucleophilic substitution reaction. If there are suitable leaving groups on the benzene ring, they can be replaced by nucleophilic reagents to introduce target halogen atoms. For example, a fluorobenzene derivative containing suitable leaving groups is reacted with a chlorinated nucleophilic reagent. Through the nucleophilic substitution process, chlorine atoms are introduced at specific positions in the benzene ring, and then bromine atoms are introduced in a similar method, or in another reaction step. In this process, the activity of the nucleophilic reagent and the ease of leaving the group are all key factors.
Third, the coupling reaction with the help of metal catalysis. For example, the coupling of halogenated aromatics catalyzed by palladium and halogenated reagents. Using halogenated aromatics containing chlorine and fluorine as substrates, in the presence of palladium catalyst and suitable ligands, the coupling reaction occurs with brominated reagents to construct the structure of 2-chloro-5-fluorobromobenzene. During the reaction, the activity of the catalyst, the electronic effect and the space effect of the ligand have a great influence on the rate and selectivity of the reaction. The reaction conditions need to be finely regulated to make the reaction proceed smoothly in the direction of generating the target product.
In conclusion, there are various methods for synthesizing 2-chloro-5-fluorobromobenzene, but the reaction path needs to be carefully selected and optimized according to the characteristics of the reactants, reaction conditions and target product requirements, so as to achieve the purpose of efficient and highly selective synthesis.
What are the main uses of 2-Chloro-5-Fluorobromobenzene?
2-Chloro-5-fluorobromobenzene is an important compound in the field of organic synthesis. It has a wide range of uses and has key applications in many aspects such as medicine, pesticides and materials.
In the field of medicine, this compound can be used as a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can impart specific activities and properties to drug molecules. By means of chemical synthesis, it can be linked with other functional groups to construct drug molecules with diverse structures, thereby realizing the treatment of specific diseases. For example, in some drug development for tumor diseases, intermediates derived from 2-chloro-5-fluorobrobenzene can participate in the formation of drug molecular structures that target tumor cells and inhibit tumor growth and spread.
In the field of pesticides, 2-chloro-5-fluorobrobenzene also plays an important role. Using it as a starting material, through a series of chemical reactions, pesticide products with high insecticidal, bactericidal or herbicidal activities can be synthesized. Due to its special substituents, synthetic pesticides can exhibit high biological activity against specific pests or weeds, and have relatively little impact on the environment, which meets the needs of modern green pesticide development.
In the field of materials science, this compound can be used to synthesize organic materials with special properties. After appropriate reaction, introducing it into the main chain or side chain of polymer materials can improve the thermal stability, optical properties or electrical properties of materials. For example, synthesizing organic luminescent materials with specific fluorescence properties for optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve the luminous efficiency and stability of devices.
2-chloro-5-fluorobromobenzene is an important basic raw material in the fields of medicine, pesticides and materials science due to its unique chemical structure, providing key support for technological innovation and Product Research & Development in various fields.
What are the precautions in storage and transportation of 2-Chloro-5-Fluorobromobenzene?
2-Chloro-5-fluorobromobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to.
Let's talk about storage first. This compound may be more active in nature and is highly susceptible to external factors. Therefore, it must be stored in a cool, dry and well-ventilated place. Do not place it in a high temperature or humid place to prevent it from deteriorating. High temperature can easily cause chemical reactions, and humid environment may cause reactions such as hydrolysis, which will damage its quality. And it should be kept away from fire and heat sources. Because it may be flammable, there is a risk of combustion and explosion in case of open flames and hot topics. At the same time, it should be stored separately from oxidizing agents, acids, alkalis, etc., to avoid dangerous chemical reactions caused by contact with them.
As for transportation, there are also many key points. Transportation vehicles must ensure good ventilation conditions to prevent the accumulation of harmful gases in the car. During loading and unloading, the operation must be gentle, not brutal loading and unloading, so as to avoid packaging damage. If the packaging is damaged, 2-chloro-5-fluorobromobenzene leakage will not only cause material loss, but also may cause harm to the environment and personnel. During transportation, pay close attention to weather changes. In case of bad weather, such as heavy rain, high temperature, etc., corresponding protective measures should be taken. For transportation personnel, professional training is required to be familiar with the characteristics of this compound and emergency treatment methods. In case of an accident, they can respond in a timely and appropriate manner. In this way, the safety of 2-chloro-5-fluorobromobenzene during storage and transportation can be ensured.
2-Chloro-5-Fluorobromobenzene impact on the environment and human health
2-Chloro-5-fluorobromobenzene is also an organic compound. Its impact on the environment and human health cannot be ignored.
First talk about its effect on the environment. If this compound is released in nature, or in the migration and transformation between soil and water bodies. In the soil, or due to its own physical and chemical properties, it adsorbs on the surface of soil particles, causing gradual changes in soil properties and affecting vegetation growth. And it may enter rivers, lakes and seas with precipitation runoff. In the water body, because it is difficult to degrade, it can accumulate for a long time, endangering aquatic organisms. Or interfere with the physiological functions of aquatic organisms, such as destroying their respiratory and reproductive systems, causing changes in population numbers and disturbing ecological balance. Or volatilize into the atmosphere, participate in photochemical reactions, affect air quality, and cause bad weather such as haze.
As for the impact on human health, it should not be underestimated. If people are exposed to this compound through breathing, diet or skin, they can cause health damage. Inhalation may irritate the respiratory tract, causing cough, asthma and other diseases, and even damage lung function. Those who eat it by mistake can harm the digestive system, causing nausea, vomiting, abdominal pain, diarrhea and diarrhea. If exposed to skin, it may cause allergies, redness, swelling, and itching. Long-term exposure to this compound may be potentially carcinogenic, as it can cause gene mutations in human cells, disrupt normal physiological metabolism, and endanger life.
Therefore, in the production and use of 2-chloro-5-fluorobromobenzene, care should be taken to prevent it from escaping from the environment, so as to maintain ecological tranquility and human health.