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2-Chloro-4-Fluorobenzenethiolate

2-Chloro-4-Fluorobenzenethiolate

Hongda Chemical

Specifications

HS Code

591841

Chemical Formula C6H3ClFS-
Molar Mass 162.59 g/mol (approximate for the anion)
Solubility Solubility properties would depend on the counter - ion; generally may be soluble in polar organic solvents
Pka Of The Conjugate Acid 2 Chloro 4 Fluorobenzenethiol Estimated around 8 - 10 (approximate value for thiol group acidity)
Reactivity Reactive towards electrophiles due to the nucleophilic sulfur atom
Stability Can be stable under appropriate storage conditions; sensitive to air and moisture in some cases

As an accredited 2-Chloro-4-Fluorobenzenethiolate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - chloro - 4 - fluorobenzenethiolate packaged in a sealed, labeled chemical - grade bottle.
Storage 2 - chloro - 4 - fluorobenzenethiolate should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be stored in a tightly - sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or reaction. Keep it separate from oxidizing agents and incompatible substances to avoid dangerous chemical reactions.
Shipping 2 - chloro - 4 - fluorobenzenethiolate, being a chemical, requires careful shipping. It should be in properly sealed, corrosion - resistant containers, following all relevant hazardous materials regulations, ensuring safe transit.
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2-Chloro-4-Fluorobenzenethiolate 2-Chloro-4-Fluorobenzenethiolate
General Information
Historical Development
The development of 2-chloro-4-fluorophenylthiophenol has its origin. In the past, all the sages were in the field of chemistry, diligently exploring, wanting to obtain new things to meet the needs of all things. At the beginning, they only knew a little about compounds containing chlorine and fluorine, but everyone was determined to study them for many years and never stopped.
At some point, a wise man noticed the possibility of a combination of the two, and then started a research journey. After countless attempts, in the synthesis method, repeated thinking, or changing its raw materials, or changing its conditions, it was difficult and difficult to achieve. Finally, the embryonic form of 2-chloro-4-fluorophenylthiophenol salt was obtained. Since then, scholars have continuously refined their preparation techniques, resulting in a significant increase in both quality and quantity of this product. It has gradually become useful in chemical, pharmaceutical, and other industries, paving the way for the development of chemistry in later generations.
Product Overview
Description of 2-chloro-4-fluorobenzothiophenate
There is currently a product called 2-chloro-4-fluorobenzothiophenate. It is an object of chemical research and is quite useful in various fields of chemical industry.
This product has specific properties. Looking at its shape, it may be in the shape of a powder, and its color is light or nearly white. Smell it, and the smell is also unique, but it is not pungent and intolerable.
Its properties can also be described. In the reaction environment, it shows a lively state. When encountering a certain type of reagent, it can undergo subtle changes and produce new substances. This is because of its structure, chlorine and fluorine atoms give special activity.
When preparing, it is necessary to follow exquisite methods, temperature control and speed regulation, which are all key. All conditions are in harmony to get this good product. And during the storage period, it also needs to pay attention to the environment, avoid moisture and light, so as to keep its stability for subsequent use and contribute to the exploration of chemical industry.
Physical & Chemical Properties
2-Chloro-4-fluorothiophenol salt This material has unique physical and chemical properties. Its color may be light, almost colorless and transparent, like the purity of morning dew. Looking at its state, it is a flowing liquid at room temperature, with a quality like thin oil, smooth and flexible.
When it comes to the melting point, it is located in a specific low temperature zone. When it is cold, it gradually condenses, like water on a cold night turning into ice. The boiling point also has an exclusive value. When heated to that time, it turns into a gas phase and rises.
Its solubility, in a specific organic solvent, such as a fish in water, blends seamlessly; however, in water, it is like oil floating on water, which is difficult to dissolve. On top of the chemical activity, it can react with many reagents, or form new substances, which change wonderfully, like magic, adding many possibilities for chemical research.
Technical Specifications & Labeling
Today there is a thing called 2 - Chloro - 4 - Fluorobenzenethiolate. The method of making it needs to be based on the technical specifications and identification (commodity parameters).
To make this thing, prepare all kinds of raw materials first, and put them in order according to the precise quantity. When reacting, the temperature, pressure and time all need to be in line, and if there is a slight difference, the quality is difficult to guarantee. The utensils used also need to be clean and non-destructive to avoid impurities from mixing.
After making it, it should be screened in detail according to the identification (commodity parameters). Looking at its color, it should be pure but not heterogeneous; observing its state, it must be in line with the determined state. More instruments are used to measure its composition and purity, so that all its parameters meet the specifications.
According to this technical specification and identification (product parameters), a high-quality 2 - Chloro - 4 - Fluorobenzenethiolate can be obtained to meet the needs of all parties.
Preparation Method
To prepare 2-chloro-4-fluorobenzene thiophenate, the method is as follows:
Raw materials and production process: Select high purity 2-chloro-4-fluorohalobenzene and sulfur-containing nucleophilic reagents as raw materials. In a suitable reaction vessel, dissolve the raw materials with a specific organic solvent, which needs to have good solubility to the reactants and stable chemical properties.
Reaction steps: Adjust the temperature of the reaction system to an appropriate range, usually between [X] ° C and [X] ° C, with slow stirring, add the sulfur-containing nucleophilic reagent dropwise to the 2-chloro-4-fluorohalobenzene solution. After adding the drops, maintain the temperature and continue the reaction for several hours. During this period, the reaction progress can be closely monitored, which can be observed by thin-layer chromatography.
Catalytic mechanism: Adding an appropriate amount of a specific catalyst can reduce the activation energy of the reaction and accelerate the reaction rate. The catalyst interacts with the reactants to promote the fracture and formation of chemical bonds and improve the production efficiency of the product. After these operations, the product of 2-chloro-4-fluorophenylthiophenol salt can be obtained. After separation and purification, a high-purity product can be obtained.
Chemical Reactions & Modifications
In the field of chemistry, the reaction and modification of this compound are particularly important to our generation.
Observe its reaction, and observe the state of its chemical combination with other substances in the past. If it encounters nucleophiles, it often changes from nucleophilic substitution. The sulfur atoms of thiols are quite nucleophilic, and they are easy to interact with substrates such as halogenated hydrocarbons to form new chemical bonds and structure other molecules.
Regarding its modification, or adding functional groups to change its physical and chemical properties. If a specific group is introduced, its solubility and reactivity can be adjusted. Or borrow the methods of light, heat, and catalysis to change its molecular configuration and make it have different activities and functions.
Our chemical researchers should explore the wonders of its reactions and study the modification methods carefully, hoping to be able to expand its new path and increase its use in the field of chemistry.
Synonyms & Product Names
2-Chloro-4-fluoro-thiophenol salt is a new product of chemistry. Its heteronym and trade name are related to the importance of the researcher. The heteronym of this product may be called because of its shape, nature, and system. Looking at the history of Fugu, the name is established, and there must be a reason.
In the chemical environment, 2-chloro-4-fluoro-thiophenol salt, its molecular structure, chlorine, fluorine are combined with phenyl ring and thiophenol salt, forming this unique body. Its heteronym, or from the group of its elements, or from the connection of its bonds. As for the business name, it is related to the promotion of the city's business and industry. The name of a good person can attract the attention of the public and facilitate its sale.
The researcher is in the room, studying the nature of this product, exploring its transformation, hoping to use the analysis of different names and business names to clarify its position in the industry and its use in the world. Although the name is many, its quality is also the same, all of which are studied by the researcher, wanting to reveal its secrets, so that it can be used in a wide area, benefiting people's lives, and promoting karmic prosperity.
Safety & Operational Standards
Code for safety and operation of 2-chloro-4-fluorothiophenol
Fu 2-chloro-4-fluorothiophenol is an important substance in chemical research. In its experimental operation and research process, safety is the most important and bears the brunt.
At the beginning of operation, read the relevant safety materials carefully. If it is done in a well-ventilated place, if it is in a closed space, harmful gases will accumulate and endanger the human body. And protective equipment, such as protective clothing, protective gloves and goggles, is required to prevent the substance from touching the skin and eyes, because it may be corrosive and irritating.
When taking it, follow the rules of precise measurement. Measure with suitable utensils, do not pour at will, causing deviation in the amount, affecting the experiment, and or causing danger. When transferring substances, be careful to prevent them from splashing.
When storing, choose a suitable container. It should be well sealed to avoid excessive contact with air and moisture, because of its active chemical properties, or react with substances in the environment. And store in a cool, dry place, away from fire and heat sources, to prevent it from changing its properties due to changes in temperature and humidity, or even causing disasters such as fires and explosions.
Experimental operation steps, strictly follow established procedures. If there are operations such as heating and stirring, control the temperature and rate, and gradually. After the operation is completed, properly dispose of the remaining substances and waste, and store and dispose of them in accordance with environmental protection requirements. Do not discard them at will, so as to avoid polluting the environment.
In short, in the research and application of 2-chloro-4-fluorothiophenol salts, safety and operation standards, such as car wheels and bird wings, are indispensable. Researchers must always keep in mind to ensure the smooth operation of the experiment and protect themselves and the environment.
Application Area
Today there is a thing called 2 - Chloro - 4 - Fluorobenzenethiolate, which has a wide range of uses. In the field of medicine, it can help doctors develop wonderful prescriptions and cure various diseases. Because of its unique nature, it can accurately act on lesions, or relieve pain and save lives.
In the craftsmanship room, it is also very useful. It can help craftsmen, optimize the texture in the process of material refining, make the utensils more tough and durable, and the color is more exquisite.
In addition, in the field of agronomy, it can be used as a good medicine to protect seedlings. Help crops resist pests, keep five grains abundant, and people have no worries about food and clothing. These three are the application fields of 2 - Chloro - 4 - Fluorobenzenethiolate, which are really good things for the world.
Research & Development
In recent years, the product of 2-chloro-4-fluorobenzothiophenate has been studied and developed. At the beginning, its chemical properties were analyzed, its structure was explored, and the rules of its reaction were known. In the method of synthesis, new methods were tried many times, and efficient paths were obtained. After repeated tests, the temperature was adjusted, the ratio was controlled, or new agents were used, and progress was made. This product may be useful in various fields, but it also encounters problems. The removal of impurities and the increase in yield are all yet to be solved. We should do our best, follow the scientific method, and continue to seek breakthroughs, so as to promote the great cause of this product in research and progress, and make achievements and benefit the world.
Toxicity Research
The toxicity of 2-chloro-4-fluorothiophenol salt is an important matter for people's health and environmental safety. Examine its chemical structure, the characteristics of chlorine and fluorine atoms in detail, or affect its reactivity and toxicity.
After experimental investigation, at specific concentrations, this compound exhibited certain toxic effects on the tested organisms. For aquatic organisms, it may cause physiological disorders and hinder growth and development. In the soil environment, it may also interfere with the balance of microbial communities and affect the normal operation of soil ecosystems.
Although the mechanism of toxic action is not fully understood, it is speculated that it may be related to the inhibition of key enzyme systems in organisms by this compound. In the future, it is necessary to deepen research, expand the scope of experiments, and consider the interaction of multiple factors in order to accurately evaluate its toxicity hazards and safeguard environmental safety and human health.
Future Prospects
Fu 2 - Chloro - 4 - Fluorobenzenethiolate This compound has an extraordinary future in the field of chemical research in my country. Looking at the progress of today's chemistry and the increasing prosperity of fine chemicals, this compound will emerge in the fields of material synthesis and pharmaceutical research and development due to its unique structure.
In material synthesis, it can act as a key intermediate. Through delicate reactions, novel functional materials can be constructed, or with excellent electrical conductivity and optical properties, creating a new situation for the field of electronics and optics. As for pharmaceutical research and development, with its special chemical properties, it is expected to derive special drugs to overcome difficult diseases and benefit the common people.
Our researchers should diligently study and explore its endless potential with scientific methods and innovative ideas. In time, 2 - Chloro - 4 - Fluorobenzenethiolate will shine like a star in the future of chemistry, contributing to the well-being of mankind and becoming an unparalleled cause.
Where to Buy 2-Chloro-4-Fluorobenzenethiolate in China?
As a trusted 2-Chloro-4-Fluorobenzenethiolate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chloro-4-Fluorobenzenethiolate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Chloro-4-Fluorobenzenethiolate?
2-Chloro-4-fluorothiophenol salt is an important compound in organic chemistry. It has a wide range of uses and is used in many fields.
First, in the field of pharmaceutical chemistry, it can be used as a key intermediate. In the process of drug development, many complex drug molecules are often constructed with the help of this compound. Due to its specific chemical structure, it can participate in a variety of chemical reactions, thus laying the foundation for the synthesis of drug molecules with specific physiological activities. For example, it can react with other reagents to build a specific chemical skeleton, which can give drugs unique pharmacological effects, such as antibacterial and antiviral effects.
Second, in the field of materials science, 2-chloro-4-fluorophenylthiophenol also plays an important role. In the preparation of some high-performance materials, it can be used as a modifier or a reaction raw material. After appropriate chemical reactions, it can be introduced into the structure of the material to improve the properties of the material. For example, to enhance the stability of the material, change the optical or electrical properties of the material, etc., making the material more suitable for specific application scenarios such as electronic devices and optical materials.
Third, in the field of organic synthetic chemistry, it is a commonly used synthetic block. Chemists can use it to react with different functional groups through nucleophilic substitution, coupling, etc., to construct complex and diverse organic molecular structures. By carefully designing reaction routes and using them as starting materials, organic compounds with various structures and functions can be synthesized, which greatly enriches the types of organic compounds and promotes the development of organic synthetic chemistry.
In summary, 2-chloro-4-fluorothiophenol salts have shown indispensable value in many fields such as drugs, materials and organic synthesis due to their unique chemical properties, providing important chemical tools and material bases for the development of various fields.
What are the physical properties of 2-Chloro-4-Fluorobenzenethiolate?
2-Chloro-4-fluorobenzenthiophenol salts are a class of organic compounds. This compound has specific physical properties, which are described in detail by you today.
Looking at its morphology, under normal temperature and pressure, it is mostly in a solid state. Due to the moderate intermolecular force, the molecules are arranged in an orderly manner, so they form a solid state. Its color is often white or off-white, with pure color and no noise, just like the purity of first snow, and the warmth of suet jade.
When it comes to melting point, due to the presence of chlorine and fluorine atoms in the molecular structure, the intermolecular force is enhanced, so the melting point is higher. This property is very important in chemical applications. It can be separated and purified under specific temperature conditions. For example, by sublimation, the substance is directly converted from the solid state to the gaseous state, and then cooled back to the solid state to obtain a pure product.
In terms of solubility, 2-chloro-4-fluorothiophenol salts show good solubility in organic solvents such as ethanol and ether. This is because the organic solvent molecules can form specific interactions with the compound molecules, such as van der Waals force, hydrogen bonds, etc., so that the two can blend with each other, just like fish and water. In water, its solubility is poor, because its molecules are non-polar or weakly polar, and it is difficult to be compatible with polar water molecules, just like the mutual exclusion of oil and water.
Its density is also considerable. Compared with common water, the density is higher, and when it is placed in water, it is like a stone sinking to the bottom, slowly sinking. This characteristic can be used in chemical separation operations to distinguish different substances.
In addition, in terms of odor, it often has a special sulfur phenol odor. This smell is pungent and unique, and people can sense its existence when they smell it. In chemical production, it can be preliminarily judged whether it leaks based on the smell to prevent accidents. The physical properties of 2-chloro-4-fluorothiophenol salts are of great significance in the fields of organic synthesis and chemical production, and are valued by chemical craftsmen. They are all indispensable factors in the preparation, separation, and application of substances.
Is 2-Chloro-4-Fluorobenzenethiolate chemically stable?
The chemical stability of 2-chloro-4-fluorobenzenthiophenol salt is related to many aspects. In this compound, chlorine and fluorine atoms interact with each other according to the specific position of the benzene ring, and the electronic effect of the two interacts, which has a great impact on its chemical stability.
The chlorine atom has an electron-sucking induction effect, which can reduce the electron cloud density of the benzene ring. Although the fluorine atom also has an electron-sucking induction effect, the conjugation effect with the benzene ring is relatively weak. The two together cause the electron cloud distribution of the benzene ring to change, which in turn affects the stability of the compound.
In chemical reactions, the sulfur-phenol part of 2-chloro-4-fluorophenylthiophenol salt has a lone pair of electrons, and its nucleophilicity is strong, which is easy to react with electrophilic reagents. The chlorine and fluorine atoms on the benzene ring can affect the check point and rate of the reaction.
Furthermore, environmental factors cannot be ignored. The increase in temperature may increase the intra-molecular energy and the molecular motion intensifies, making the chemical bond more prone to break and the stability decreases. The change in humidity, if the environment is humid, the moisture may participate in some chemical reactions, which affects its stability.
However, under certain conditions, this compound may remain relatively stable. For example, in a dry, low-temperature environment without active reagents, its stability may be maintained. However, in general, due to the complex interactions between atoms in its structure and the high activity of some atoms, its chemical stability is not very high. Under normal conditions, it needs to be stored and used with caution to prevent it from chemical reactions and deterioration.
What is 2-Chloro-4-Fluorobenzenethiolate synthesis method?
The synthesis of 2-chloro-4-fluorobromobenzene thiophenates is a key research in the field of organic synthesis. Its synthesis steps are complicated and require delicate operation.
The selection of starting materials is very important, and 2-chloro-4-fluorobrobenzene is often used as the starting material. The reaction of this raw material with the sulfur source is the key to the synthesis. In a suitable reaction vessel, place 2-chloro-4-fluorobrobenzene in an inert gas atmosphere, such as nitrogen, to prevent side reactions between the raw material and the components in the air.
Subsequently, add a sulfur source. Common sulfur sources such as sodium sulfide, sodium hydrosulfide, etc. Temperature control is critical at this step. If the temperature is too high, although the reaction rate increases, it is prone to produce many by-products; if the temperature is too low, the reaction will be delayed and the yield will decrease. Generally speaking, the reaction temperature is usually controlled between 50 and 80 ° C, depending on the solvent used and the concentration of the reactants.
The choice of solvent also affects. Common polar aprotic solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc. Such solvents can effectively dissolve the reactants, promote the reaction between ions, and improve the reaction efficiency.
During the reaction process, sufficient stirring is required to make the reactants contact evenly and accelerate the reaction process. When the reaction reaches the expected level, the reaction endpoint can be monitored by thin layer chromatography (TLC) and other means.
After the reaction is completed, the product separation and purification are essential. First, the product is extracted from the reaction system with a suitable organic solvent, such as ethyl acetate. Then, by column chromatography, suitable silica gel and eluent are selected to further purify the product to obtain pure 2-chloro-4-fluorothiophenol salt.
Although the above synthesis method is a common path, in practice, researchers still need to optimize each step according to specific experimental conditions and needs to achieve better synthesis results.
2-Chloro-4-Fluorobenzenethiolate What are the precautions in storage and transportation?
For 2-chloro-4-fluorothiophenol salts, many matters should be paid attention to during storage and transportation.
First words storage, this substance should be placed in a cool, dry and well-ventilated place. Because it may be sensitive to heat and moisture, it is important to avoid high temperature and humidity. If it is exposed to high temperature environment, it may not cause its chemical properties to change, or even cause adverse conditions such as decomposition; in case of moisture, or deterioration due to moisture absorption, affecting its quality and stability. In addition, it should be placed separately from oxidizing agents, acids and other substances. Dangerous when 2-chloro-4-fluorothiophenol comes into contact with oxidizing agents or undergoes a violent oxidation reaction; contact with acids may also trigger chemical reactions that cause them to fail or produce harmful by-products. Storage containers should also be carefully selected, and corrosion-resistant materials, such as specific plastic or metal containers, should be used to prevent the container from being corroded and causing material leakage.
As for transportation, there are also many details. Before transportation, it is necessary to ensure that the packaging is intact. Packaging should be able to resist vibration, collision and friction to prevent package damage during transportation. Transportation tools should also be kept clean and dry to avoid mixing with other substances that may react. During transportation, pay close attention to changes in temperature and humidity, and take timely control measures. For long-distance transportation, it is necessary to strengthen monitoring to ensure that the transportation environment is suitable. In addition, transportation personnel should be familiar with the characteristics of this substance and emergency treatment methods. In case of leakage and other accidents, they can respond quickly and correctly to minimize harm.