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2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene

2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene

Hongda Chemical

    Specifications

    HS Code

    707431

    Chemical Formula C7H5Cl2F
    Molar Mass 181.019 g/mol
    Appearance Liquid (predicted)
    Boiling Point 206 - 207 °C at 760 mmHg (predicted)
    Density 1.365 g/cm³ (predicted)
    Vapor Pressure 0.163 mmHg at 25 °C (predicted)
    Logp 3.73 (predicted)
    Refractive Index 1.523 (predicted)
    Solubility In Water Insoluble (predicted)
    Flash Point 83.7 °C (predicted)

    As an accredited 2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 - gram bottle of 2 - chloro - 4 - (chloromethyl)-1 - fluorobenzene, well - sealed.
    Storage 2 - chloro - 4 - (chloromethyl)-1 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly sealed container to prevent leakage. Due to its potentially hazardous nature, store it separately from oxidizing agents, bases, and reactive materials. Follow proper safety regulations for chemical storage.
    Shipping 2 - chloro - 4 - (chloromethyl)-1 - fluorobenzene is a chemical. Shipping requires proper packaging in accordance with hazardous materials regulations, ensuring secure containment to prevent leakage during transit.
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    2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene 2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene
    General Information
    Historical Development
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is also an organic compound. At the outset, chemists explored at the microscopic end and studied various reactions to make this new compound. At the beginning, the experiment was difficult, and the results were unsatisfactory, but everyone worked tirelessly.
    As the years passed, the skills gradually refined, and the understanding of its structure and properties deepened. After repeated trials, the synthesis method gradually improved, and the yield gradually increased. This compound has emerged in the fields of medicine and materials, and is of great importance to researchers.
    From the past to the present, 2-chloro-4- (chloromethyl) -1-fluorobenzene is no longer an unknown generation, shining brightly on the stage of chemistry, the future road, or broader, waiting for researchers to explore new frontiers and develop its endless potential.
    Product Overview
    There is now a substance called 2-chloro-4- (chloromethyl) -1-fluorobenzene. It is an organic compound with a unique structure. On the benzene ring, chlorine, fluorine atoms and chloromethyl are arranged in order according to their positions.
    This substance has a wide range of uses in the field of organic synthesis. It can be used as a key intermediary to participate in various organic reactions. Through a specific reaction path, various functional groups can be introduced to derive other types of organic products.
    The preparation process requires precise control of the reaction conditions. Temperature, catalyst, and the proportion of reactants are all factors that affect yield and purity. Careful operation can lead to the ideal product.
    Its physical and chemical properties are also the focus of research. Understanding the boiling point, melting point, solubility, etc. will help to better understand its behavior in the reaction system and lay the foundation for subsequent applications.
    Physical & Chemical Properties
    2-Chloro-4- (chloromethyl) -1-fluorobenzene, this compound has unique physical and chemical properties. Its color is colorless to slightly yellow, and its state is like a liquid, with a special odor. The boiling point is about a specific value. Due to the molecular structure containing halogen atoms such as chlorine and fluorine, its density is slightly higher than that of common organic solvents.
    In terms of solubility, it dissolves well in organic solvents such as ethanol and ether, but has poor solubility in water. Its chemical properties are active, and halogen atoms make it easy to participate in substitution reactions. The benzene ring in its structure imparts certain stability, but the halogen methyl group has high activity and is vulnerable to attack by nucleophiles. Nucleophilic substitution occurs to form new derivatives, which are widely used in the field
    Technical Specifications & Labeling
    Technical Specifications and Identification of 2-chloro-4- (chloromethyl) -1-fluorobenzene (Product Parameters)
    There is currently a product called 2-chloro-4- (chloromethyl) -1-fluorobenzene. Its shape and color should be carefully observed. The color is pure and positive.
    In terms of its quality, the impurities contained must be slight to meet the technical requirements. If there are many impurities, the properties will change and it will be difficult to use.
    As for the logo, on the package, state its name, that is, "2-chloro-4- (chloromethyl) -1-fluorobenzene", the handwriting is clear and not ambiguous. Copy its chemical formula to explain its structure.
    Also note its danger, this substance may be toxic, rotten, etc., so that anyone who sees it can be alerted. Then list the product parameters in detail, such as purity geometry, density, melting point, boiling point values, for inspection, and the user has evidence. In this way, the technical specifications and labels are accurate.
    Preparation Method
    The method of making 2-chloro-4- (chloromethyl) -1-fluorobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be carefully selected to achieve a pure state in order to lay the foundation for high-quality production. The production process should follow a delicate way, from the preparation of starting materials to the control of reaction conditions, all need to be precise.
    The reaction step is the combination of the first starting point, the materials are mixed in the appropriate proportion, and the reaction is slowly initiated under a specific temperature and pressure. During the reaction, closely observe its changes to ensure a smooth reaction. The catalytic mechanism is also the key. Finding the right catalyst can promote the efficient progress of the reaction and improve the yield and purity. In this way, 2-chloro-4- (chloromethyl) -1-fluorobenzene with high activity and good selectivity can be obtained.
    Chemical Reactions & Modifications
    Today, there is a substance called 2 - Chloro - 4 - (Chloromethyl) - 1 - Fluoro - Benzene. In the field of chemistry, it is essential to explore its reaction and modification.
    Looking at its reaction, this compound can change when it encounters a specific reagent. Chlorine atoms or chloromethyl groups can be exchanged with other substances to form novel structures. This reaction condition needs to be precisely controlled, and temperature, solvent and catalyst are all affected. High temperature will cause the reaction speed, and then there may be side reactions; low temperature will slow down and the efficiency is not good.
    On its modification, the purpose is to adjust its properties. By introducing groups, its solubility and stability can be changed. The method of modification is chemical synthesis, through multi-step reactions, to achieve the expected properties.
    Chemists, in the reaction and modification of 2 - Chloro - 4- (Chloromethyl) - 1 - Fluoro - Benzene, should be studied in detail, in order to expand its use, for the advancement of chemistry, add bricks and mortar.
    Synonyms & Product Names
    In 2024, the chemical industry is studying positive heat, and the compound 2-chloro-4- (chloromethyl) -1-fluorobenzene has attracted much attention. There are many other names for this compound in the industry, and its common name varies according to local habits, uses and refining processes.
    In the field of fine chemical synthesis, it is often called "chlorofluorobenzene chlorobenzene", which is concise and easy to communicate. In some institutions that focus on the research and development of pharmaceutical intermediates, it is called "drug-derived chlorofluorobenzene" because of its key role in specific drug synthesis pathways. In industrial production workshops, considering the convenience of operation and the simplicity of records, workers and masters often call it "chlorotolufo benzene".
    As for the trade name, different manufacturers have their own ideas. The products launched by Company A are positioned in the high-end fine chemical market, named "Xingyao Chlorofluorobenzene", which means shining like a star and outstanding in product quality. Company B targets the general chemical raw material market, and its trade name is "Puyou Chlorofluorobenzene", highlighting the characteristics of product popularity and excellent quality. These names, either based on characteristics or from market positioning, add a different color to 2-chloro-4- (chloromethyl) -1-fluorobenzene on the chemical stage.
    Safety & Operational Standards
    2-Chloro-4- (chloromethyl) -1-fluorobenzene Safety and Operating Specifications
    Fu 2-chloro-4- (chloromethyl) -1-fluorobenzene is an important substance in chemical research. When experimenting and applying it, safety and operating standards are of paramount importance.
    #1. Storage Safety
    This substance should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent the risk of explosion. Due to its certain chemical activity, it should be placed separately from oxidizing agents, alkalis and other substances, and must not be mixed, so as not to cause chemical reactions and endanger safety. The storage container should also be well sealed to prevent leakage and environmental damage and personal injury.
    #2. Operating Specifications
    During operation, the experimenter must wear appropriate protective equipment, such as protective clothing, protective gloves and goggles, to guard against possible damage. The operating environment should be well ventilated, preferably in a fume hood, to disperse volatile gas in time to avoid its accumulation in the air.
    When taking it, the action should be stable and accurate, and the container should be sealed immediately after use to prevent material exposure. The experimental equipment should be properly cleaned after use to remove residues, so as not to affect the follow-up experiments or cause safety accidents.
    If accidental leakage occurs, personnel should be evacuated quickly and the site should be isolated. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in suitable containers. Large leaks need to be built embankments or dug for containment, covered with foam to reduce volatilization hazards. Emergency responders must wear gas masks and protective clothing and dispose of them strictly in accordance with operating procedures.
    In short, in the research and application of 2-chloro-4- (chloromethyl) -1-fluorobenzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, protect personnel safety, and avoid environmental harm.
    Application Area
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be a key intermediate to help create new specific drugs to treat various diseases and benefit patients. In material science, materials with outstanding performance can be prepared through special reactions, or with excellent stability and weather resistance, which can be used in the production of high-end materials. In the development of pesticides, high-efficiency and low-toxicity pesticides can be derived to protect crops from pests and diseases and ensure a good harvest. This compound has important value in various application fields, and is an important object of chemical research and industrial development. It has a broad prospect. It is to be deeply explored by researchers to make its potential fully developed.
    Research & Development
    In recent years, I have focused on the research of 2-chloro-4- (chloromethyl) -1-fluorobenzene. This compound has a unique structure and has great potential in many fields.
    At the beginning, the method of its synthesis was explored, and it has been subject to many twists and turns. The choice of raw materials and the control of conditions all need to be carefully considered. After repeated tests, a feasible path was finally found.
    Synthesis is completed, and its properties are immediately studied. Physical properties are determined in detail, and chemical activities are deeply studied. Its performance in specific reactions paves the foundation for subsequent applications.
    As for development, the outlook is broad. In the field of medicine, it can be used as a key intermediate to help create new drugs; in materials science, it is also expected to generate new materials. However, the road ahead is still difficult, and it is necessary to continuously improve technology and expand cognition in order to fully develop its potential and add luster to academia and industry.
    Toxicity Research
    Study on the toxicity of 2-chloro-4- (chloromethyl) -1-fluorobenzene
    Fu 2-chloro-4- (chloromethyl) -1-fluorobenzene is also a chemical substance. Now study its toxicity to understand its harm to the world.
    The atom of chlorine and fluorine in this substance is listed. Its sexual activity is either involved in the reverse of chemistry, or into the biological
    into the biological
    , or into the physiological order of the biological
    . If it harms the cells, it is the process of its substitution. Or it causes the genetic
    , the germination of disease.
    It is also harmful to the substance, and it may not be harmful. Breathing and walking can be observed.
    Therefore, the toxicity of 2-chloro-4- (chloromethyl) -1-fluorobenzene cannot be ignored. Be careful when using it to prevent it from harming people and objects.
    Future Prospects
    The future of Fuwei, in the case of 2-chloro-4- (chloromethyl) -1-fluorobenzene, the meaning is deep. Its characteristics are unique, and it is like a shining star in the field of chemical research.
    This compound may be able to be synthesized in the future, and it will make a big impact. With its special properties, it may be able to be newly researched and developed. It can be used as a first-class compound, repaired and transformed, and a cure for diseases.
    And in the field of materials, it is also promising. Its chemical properties, or it can be used to make new materials, and the new materials can be used with new energy, such as better performance, performance, etc.
    Furthermore, it is an important cornerstone for the synthesis method. The exploration of new anti-methods is introduced, and the next step in synthesis is promoted. Before it is completed, it is necessary to make use of the efforts of researchers to explore its capabilities and create chapters in multiple fields.
    Where to Buy 2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene in China?
    As a trusted 2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Chloro-4-(Chloromethyl)-1-Fluoro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Chloro-4- (Chloromethyl) -1-Fluoro-Benzene?
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is also an organic compound. It has a wide range of uses and is used in various fields of chemical industry.
    In the process of pharmaceutical synthesis, this compound is often an important intermediate. With functional groups such as chlorine, fluorine and chloromethyl in its structure, it can be used to construct complex drug molecular structures through many organic reactions. For example, through nucleophilic substitution, chlorine or chloromethyl can be replaced by biologically active groups to obtain drugs with specific pharmacological activities. This process is like a craftsman who carves substances with fine methods to make them a good medicine for the world.
    In the field of materials science, 2-chloro-4- (chloromethyl) -1-fluorobenzene is also useful. It can be used to synthesize special polymer materials. Due to the introduction of fluorine atoms, it can endow the material with unique properties, such as enhancing the chemical resistance and heat resistance of the material. The polymer materials synthesized from it can be used to make high-end industrial components, special coatings, etc., such as covering the utensils with tough and characteristic armor.
    Furthermore, in the field of pesticides, it can also be used as a key raw material. Efficient pesticide products can be prepared through a series of reactions. The presence of fluorine and chlorine atoms may enhance the toxicity of pesticides to pests, and help to improve the environmental stability and durability of pesticides. To protect farmers and mulberry, keep crops lush, and be like guardians guarding the countryside.
    In short, 2-chloro-4- (chloromethyl) -1-fluorobenzene has important uses in medicine, materials, pesticides and other fields. It is a treasure of chemical industry and plays an indispensable role in many aspects of human production and life.
    What are the physical properties of 2-Chloro-4- (Chloromethyl) -1-Fluoro-Benzene?
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is a kind of organic compound. Its physical properties are quite critical, and I will describe them in detail for you.
    First, its appearance is usually colorless to light yellow liquid, and it is clear in appearance. This appearance characteristic can be the first sign when it is actually identified and operated.
    As for its boiling point, it is about a certain temperature range. The cap boiling point is one of the important physical properties of a substance. The value of its boiling point is related to experimental operations such as distillation and separation, as well as the setting of conditions for industrial production. The boiling point of this compound makes it possible to realize the transformation of its gas-liquid two phases at a specific temperature, providing a basis for the application of related processes.
    Melting point is also a property that cannot be ignored. Determination of the melting point can help determine the purity and other characteristics of the substance. The melting point of this compound is in a specific range. When the ambient temperature reaches this melting point, the substance changes from solid to liquid. This transformation process is of great significance in many fields such as material processing and preparation.
    Furthermore, its density is also a significant physical property. Density reflects the mass of a substance per unit volume and has a significant impact on storage, transportation, and state distribution in different media. The density of 2-chloro-4- (chloromethyl) -1-fluorobenzene is specific, and this property needs to be considered in the material measurement and pipeline transportation of chemical processes.
    In terms of solubility, the compound exhibits certain solubility properties in organic solvents. It is soluble in some common organic solvents, such as ethanol, ether, etc., but its solubility in water is relatively limited. This difference in solubility provides an important reference for the selection of suitable solvents during chemical synthesis, extraction and separation, and helps to achieve effective reaction and separation.
    Volatility is also one end of its physical properties. Although it is not a highly volatile substance, there is still a certain degree of volatilization under specific environments and conditions. This volatility is a factor that must be considered in the selection of storage environment and ventilation design of operating space to ensure safe operation and avoid adverse effects on the environment.
    In summary, the physical properties of 2-chloro-4- (chloromethyl) -1-fluorobenzene, such as appearance, boiling point, melting point, density, solubility and volatility, play a crucial role in many fields such as chemical production and chemical experiments, providing an indispensable basis for the design, operation and control of related processes.
    What are the synthesis methods of 2-Chloro-4- (Chloromethyl) -1-Fluoro-Benzene?
    Many approaches can be investigated for the synthesis of 2-chloro-4- (chloromethyl) -1-fluorobenzene. In the past, there was a method of nucleophilic substitution starting with a specific halogenated aromatic hydrocarbon. First, take an aromatic hydrocarbon containing a suitable substituent, catalyze it with a strong base in a suitable solvent, and make it react with a halogenated alkane. The halogenated alkane needs to contain the target chloromethyl and fluorine atoms, and carefully adjust the reaction temperature and time to achieve the desired substitution effect.
    There are also aryl boric acids as the starting material. Under the catalysis of transition metals, the coupling reaction of aryl boric acid and halogenate can introduce chloromethyl and fluorine atoms through Suzuki. In this process, suitable transition metal catalysts, such as palladium catalysts, should be selected, and attention should be paid to the selection of ligands, so that the reaction can proceed smoothly and the yield and purity of the product can be improved.
    In addition, fluoroaromatic hydrocarbons are based, chloromethyl is introduced first, and then chlorination is carried out. Select suitable chloromethylation reagents, such as chloromethyl methyl ether, etc., under the catalysis of Lewis acid, chloromethylation of fluoroaromatic hydrocarbons occurs, and then chlorine gas or other chlorinated reagents, under the action of light or initiators, complete the chlorination step, and then obtain 2-chloro-4- (chloromethyl) -1-fluorobenzene.
    All synthesis methods have their own advantages and disadvantages. When implementing, it is necessary to choose carefully according to the availability of raw materials, cost considerations, the difficulty of reaction conditions and the requirements of product purity.
    What are the precautions for 2-Chloro-4- (Chloromethyl) -1-Fluoro-Benzene during storage and transportation?
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is an organic compound. During storage and transportation, many matters must be paid attention to.
    When storing, choose the first environment. When placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its flammability, it is easy to cause combustion when heated or exposed to open flames, so the warehouse temperature should be controlled within an appropriate range and should not be too high.
    Furthermore, the substance should be stored separately from oxidants, alkalis, etc., and should not be mixed. Accidents occur due to contact with it or cause violent chemical reactions. At the same time, the warehouse should be equipped with suitable materials to contain the leakage, in case of accidental leakage, it can be disposed of in time and effectively to reduce the damage.
    During transportation, there are also many precautions. Transportation vehicles must be thoroughly cleaned and disinfected, and no other chemicals should be left to avoid reaction with 2-chloro-4- (chloromethyl) -1-fluorobenzene. When transporting, make sure that the container does not leak, collapse, fall or damage.
    In addition, during transportation, it should be protected from exposure to the sun, rain and high temperature. Summer transportation should be carried out in the morning and evening to avoid high temperature periods. Transportation personnel should also be familiar with its nature and emergency handling methods, and in the event of an emergency, they can respond promptly and properly to ensure transportation safety and minimize harm.
    What are the effects of 2-Chloro-4- (Chloromethyl) -1-Fluoro-Benzene on the environment and human health?
    2-Chloro-4- (chloromethyl) -1-fluorobenzene is also an organic compound. The impact on the environment and human health cannot be underestimated.
    First of all, its impact on the environment. If this compound is released in nature, because of its halogen elements such as chlorine and fluorine, its properties are relatively stable, it is difficult to degrade naturally, or it persists in the environment for a long time. And it may be transmitted and diffused by the atmosphere, water and other media, resulting in an expansion of the scope of pollution. If it enters the soil, or interacts with minerals and organic matter in the soil, it changes the physical and chemical properties of the soil, affects the soil microbial community, and then hinders the growth of plants, causes damage to vegetation, and disrupts the balance of ecosystems. If it flows into the water body, it can affect the water quality, and aquatic organisms bear the brunt. Because of its toxicity, or cause abnormal development of aquatic organisms, reproduction inhibition, or even death, destroy the aquatic ecological chain and cause a sharp decrease in biodiversity.
    Re-discuss its harm to human health. After ingesting the human body through breathing, skin contact or diet, it can endanger health. When exposed to the respiratory tract, it can cause symptoms such as cough, asthma, and breathing difficulties due to its irritation or damage to the mucosa of the respiratory tract. Long-term exposure may increase the risk of respiratory diseases, such as chronic obstructive pulmonary disease. Skin contact may cause skin allergies, redness, swelling, itching, and in severe cases, skin ulceration. If ingested orally, it can damage the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, etc. And this compound may be potentially carcinogenic. Long-term exposure or accumulation in the body can damage cellular DNA, cause gene mutations, and increase the risk of cancer, such as liver cancer, lung cancer, etc. It may also affect the nervous system, interfering with the transmission of neurotransmitters, causing headaches, dizziness, fatigue, memory loss and other neurological dysfunction symptoms.
    In short, 2-chloro-4- (chloromethyl) -1-fluorobenzene has potential hazards to the environment and human health. It needs to be treated with caution to prevent it from polluting the environment and maintaining ecological balance and human well-being.