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2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene

2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    358859

    Chemical Formula C7H3ClF3NO2
    Molecular Weight 225.55
    Appearance Typically a liquid
    Boiling Point Data needed
    Melting Point Data needed
    Density Data needed
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents
    Vapor Pressure Data needed
    Flash Point Data needed
    Pka Data needed
    Logp Data needed

    As an accredited 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene in sealed chemical - grade containers.
    Storage 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture. Follow proper labeling and safety regulations for hazardous chemicals.
    Shipping 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene is a chemical. Shipping requires compliance with hazardous material regulations. It must be properly packaged, labeled, and transported by carriers licensed for such chemicals to ensure safety.
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    2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    2-Chloro-1-nitro-3- (trifluoromethyl) benzene, this chemical substance, its development process contains many twists and turns. At the beginning, scholars devoted themselves to research in the laboratory, trying to find a way to synthesize it. At that time, the technology was limited, the synthesis process was difficult and suffered many setbacks. However, the ancestors did not stop due to difficulties and tried new paths unremittingly.
    With the passage of time, science and technology have advanced, and new synthesis methods have gradually emerged. The experimental conditions are optimized, the selection of raw materials is more accurate, and the synthesis efficiency and purity are rising. This substance has gradually emerged in the industrial field from a rarity in the laboratory, and its application scope has gradually expanded. It has played a key role in many industries, eventually becoming an indispensable existence in the field of chemistry. Its journey is like a history of unremitting exploration.
    Product Overview
    Today there is a substance called 2-chloro-1-nitro-3- (trifluoromethyl) benzene. Its shape is also an organic compound with a special chemical structure. In this compound, chlorine atoms, nitro groups and trifluoromethyl groups are co-attached to the benzene ring.
    Chlorine atoms are located in the second position of the benzene ring, and their properties are active and can participate in a variety of nucleophilic substitution reactions. The nitro group is in the first position, which has strong electron absorption, which not only affects the electron cloud distribution of the molecule, but also reduces the electron cloud density of the benzene ring, making its chemical properties more unique. At the third position of the trifluoromethyl group, due to the extremely high electronegativity of the fluorine atom, the group also has a strong electron absorption effect, which further changes the
    This compound is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various drugs, pesticides and functional materials, etc. It occupies an important place in the chemical industry.
    Physical & Chemical Properties
    2-Chloro-1-nitro-3- (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are worth studying.
    Looking at its physical properties, it is mostly liquid at room temperature, colored or transparent, and has a special odor. Its boiling point and melting point are all fixed, and the boiling point is about a specific value. This is related to the force between molecules, van der Waals force, etc., causing it to vaporize at a certain temperature. The melting point also depends on the arrangement and structure of the molecules.
    On its chemical properties, above the benzene ring, chlorine atoms, nitro groups and trifluoromethyl groups have their own properties. Nitro groups are highly oxidizing and can participate in many reactions, making this compound exhibit an active state under specific conditions. Chlorine atoms can be substituted, creating the possibility for the derivation of new compounds. The existence of trifluoromethyl groups, due to its strong electronegativity, affects the polarity of molecules, and is reflected in reactivity and solubility. Studying the properties of this substance may be beneficial in the fields of organic synthesis, materials science, etc., which can help explore new paths and open up new horizons.
    Technical Specifications & Labeling
    Today there is a product named 2-chloro-1-nitro-3- (trifluoromethyl) benzene. To clarify its technical specifications and identification (product parameters), rigorous methods should be used.
    To observe its physical properties, it is necessary to carefully observe the color, state, taste, etc. Its color should be pure, without the disturbance of variegated colors; the state should be uniform, without the risk of agglomeration or precipitation. If there is any abnormality in taste, it is also necessary to distinguish.
    In terms of its purity, this is the key. When measured by an accurate method, it must not be lower than the specified standard, and the impurity content must be strictly controlled. On the
    logo, the name of the product should be clearly identifiable, and the parameter list must be accurate. For example, the content and specifications should be clear, so that the viewer can see it at a glance, and the essence of the technical specifications and labels should be integrated to ensure the quality of this product.
    Preparation Method
    To prepare 2-chloro-1-nitro-3- (trifluoromethyl) benzene, the method is as follows:
    Raw materials and production process: Select refined benzene as the starting material, and prepare it through multi-step reactions such as halogenation and nitrification. During halogenation, liquid chlorine is used as the halogenating agent, and under the catalysis of iron catalyst, the temperature is controlled at 60 to 80 degrees to obtain chlorobenzene.
    Reaction steps: chlorobenzene is then mixed with acid (nitric acid and sulfuric acid are mixed in a certain proportion) in a water bath and heated at 40 to 50 degrees to control the temperature. A nitrification reaction is carried out to obtain a mixture of o-nitrochlorobenzene and p-nitrochlorobenzene. After separation Then anhydrous aluminum trichloride is used as a catalyst to react with trifluoromethylation reagent to obtain the target product.
    Activation mechanism: The iron catalyst is in the halogenation to polarize the chlorine molecule and promote its reaction with the benzene ring. Sulfuric acid in the mixed acid helps nitric acid to generate nitroyl positive ions, which enhances the nitrification activity. Anhydrous aluminum trichloride interacts with trifluoromethylation reagents to produce active intermediates, which is favorable for the formation of target products.
    Chemical Reactions & Modifications
    2 - Chloro - 1 - Nitro - 3 - (Trifluoromethyl) Benzene has been studied in recent years. Its chemical reaction is also, or according to the principle of electrophilic substitution, the benzene ring is rich in electrons and is easy to attack by electrophilic reagents. However, its ring contains both chlorine, nitro and trifluoromethyl. The electronic effect and steric resistance of the groups all affect the process and direction of the reaction.
    As far as modification is concerned, if you want to change its properties, you can choose to introduce other groups. For example, add a group with specific work, or change its solubility and reactivity. Through various tests and analysis, we can adjust the temperature and pressure of the reaction and use the appropriate catalysis to improve the quality and rate of the product. Although the road ahead is still difficult, but if we continue to study it, we will be able to understand the wonders of its application, expand its use, and make progress in various fields of the chemical industry.
    Synonyms & Product Names
    Today there is a thing called 2-chloro-1-nitro-3- (trifluoromethyl) benzene. In my chemical research, this thing often has many different names, just like people in the world have different names, but they refer to the same person.
    Among its aliases, each has its own origin. Either it is obtained according to its chemical structure characteristics, or it is named differently due to the synthesis method. And on the market, there are also different trade names, all of which refer to this thing.
    When we study chemistry, we need to understand many synonymous names and trade names in order to be accurate. Only in this way can there be no confusion between academic exchanges and experimental operations, so that the research path is smooth and smooth. Don't misunderstand the major research events due to the complexity of the name.
    Safety & Operational Standards
    Specifications for safety and operation of 2-chloro-1-nitro-3- (trifluoromethyl) benzene
    Fu 2-chloro-1-nitro-3- (trifluoromethyl) benzene is a commonly used substance in chemical research. To ensure the safety of the experiment, there must be detailed rules for operation.
    This substance has certain risks. It is poisonous, or injures the human body, touches the skin, and can cause discomfort. If it enters the eyes, it is especially harmful; inhaling its gas also damages the system of breathing. And the danger of ignition and explosion should not be underestimated. In case of open flame, hot topic, or combustion, or even explosion.
    Therefore, when operating, protection is essential. Appropriate protective clothing and protective gloves must be worn to prevent skin contact. Goggles are also indispensable to avoid eye damage. In a well-ventilated place, set up an effective ventilation device to quickly discharge exhaust gas and reduce the concentration of this thing in the air.
    When storing, it should be placed in a cool, dry and ventilated place to avoid fire and heat sources. Store with oxidants, reducing agents, alkalis, etc. to prevent their reaction. The storage area should be prepared with emergency equipment and suitable containment materials.
    If you accidentally touch it, quickly rinse with plenty of water and seek medical treatment. If inhaled, move to a fresh air place, oxygen will be given for breathing difficulties, and first aid will be given if it is still not good. If a fire starts, choose the appropriate fire extinguishing agent according to its nature, such as dry powder, carbon dioxide, etc.
    In short, in the research and use of 2-chloro-1-nitro-3 - (trifluoromethyl) benzene, safety is the first priority, and follow the rules of operation to avoid disasters and complete research.
    Application Area
    Today there is a thing called 2-chloro-1-nitro-3- (trifluoromethyl) benzene. This thing has its uses in various fields.
    In the way of medicine, it can be used as a raw material, a pharmaceutical aid, and it can contribute to the treatment of diseases and diseases. Or involved in antibacterial agents, or antiviral drugs, all rely on its participation in synthesis, so as to benefit the world.
    In the field of agrochemical, it is also indispensable. It can be the basis for the creation of pesticides, the production of insect control agents, the safety of crops, and the harvest of acres. Protect crops from insect infestation and make them thrive.
    In the field of materials science, it can be used to develop new materials. Or special plastics, with unique properties, are used in industrial manufacturing, electronic devices, etc., to develop their strengths and contribute to scientific and technological progress.
    From this point of view, 2-chloro-1-nitro-3- (trifluoromethyl) benzene, although microscopic, is widely used and has extraordinary significance in people's livelihood and science and technology.
    Research & Development
    Nowadays, there is a chemical substance 2-chloro-1-nitro-3- (trifluoromethyl) benzene. As a chemical researcher, we explore its research and development. This substance has unique properties and may have potential uses in various fields of chemical industry.
    We have studied its synthesis method in detail. After many attempts, we have improved the process, hoping to improve the yield and simplify the process. We also study its reaction mechanism, clarify the chemical changes of each step, and achieve precise control.
    After repeated experiments, we have observed its reaction characteristics under different conditions, laying the foundation for its practical application. During the research and development process, we also pay attention to environmental protection and safety, and strive to make the process green and operate safely. In this way, unremitting exploration is expected to promote the self-research of this substance to a wide range of applications, contributing to the development of the chemical industry, and achieving the vision of innovation and progress.
    Toxicity Research
    2-Chloro-1-nitro-3- (trifluoromethyl) benzene is also a chemical substance. In toxicity studies, it is quite important.
    Observe the structure of its molecules, chlorine, nitro and trifluoromethyl groups, or give them unique properties. Chlorine, or increase its lipid solubility, causing easy entry into the cells of organisms. Nitro groups are highly oxidizing and cause biochemical changes in the body. The existence of trifluoromethyl alters the polarity and stability of its molecules.
    Try to study its toxicity by various methods. Feed it with experimental organisms and observe its physiological signs and behavioral changes. Examine the cellular level to see the damage it causes to cells, such as membrane breakage and enzyme inhibition. Also explore the shadow of genes to see if there is any sign of mutation.
    Today's research, although some knowledge is obtained, it is still unclear. Its long-term impact on ecology and its role in complex biological systems need to be further investigated. It is necessary to investigate carefully before we can clarify the full toxicity of it, which is the basis for safe use.
    Future Prospects
    Today there is a product named 2-chloro-1-nitro-3- (trifluoromethyl) benzene. I look at this chemical product, and its future development is quite promising.
    This product can be used in all fields of chemical industry. In the development of medicine, it may be the cornerstone of the creation of new agents, helping to overcome difficult diseases and solve the pain of the world. In the process of material research and development, it may be able to derive novel materials, add new energy and novelty, and add fuel to the progress of industry.
    Although its application may still be in the period of exploration, with time, with the advancement of scientific research and technology, it will surely shine. We scientific researchers should study it diligently and explore its potential, so that it can benefit all people in the future, add a weapon to the world, and add a blessing to the universe, so as to develop its infinite possibilities and become a brilliant future.
    Where to Buy 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene in China?
    As a trusted 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
    2-% N-1-amino-3- (triethyl) benzene, which is mostly used in the field of chemical synthesis. It is often used as a bioactive compound in the process of chemical synthesis.
    In the research of chemical compounds, this compound can be specified and reversed, and other molecular fragments can be compared. For example, it can build molecules with antibacterial, anti-inflammatory or anti-cancer activities. For example, by using antibacterial compounds, 2-% N-1-amino-3- (triethyl) benzene can be cleverly reacted to other compounds containing specific functions, so that the generated compounds have the antibacterial efficacy of specific bacteria.
    Furthermore, in the early stages of new research, researchers often use this compound as a starting material to synthesize a series of similar derivatives in a multi-step process. These derivatives can achieve biological activity and seek high activity and low toxicity. Due to its own unique characteristics, this compound can be synthesized to provide rich chemical modification possibilities, helping researchers to explore different chemical activities and accelerate new research processes.
    And because it contains active functions such as aminoacyl groups, it can also be used in synthetic synthesis to build a molecular framework for the synthesis of materials or biologically active substances with special functions. It plays an important role in the physicochemical and phase fields.
    What are the physical properties of 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
    2-% -1-amino-3- (triacetyl) benzene, this product is polyphysical. Its external surface is often solid, and the shape may vary depending on the synthesized parts and the degree of strength, or it is a crystalline powder, or it is a microgranular appearance.
    It is determined by the melting temperature, which is roughly equal to a certain degree of strength. This characteristic is one of the important factors of this product. Melting is affected by factors such as molecular force and crystallization. If the molecular force is applied, a higher energy is required to break the crystal lattice, resulting in an increase in melting temperature.
    The boiling temperature is also a specific value. Under a specific condition, the required degree of boiling is required for the material to be melted from the liquid. The molecular weight and molecular force of the boiling temperature are closely related to each other. If the molecular weight of the phase is large and the molecular force is large, the boiling temperature is often higher.
    In terms of solubility, the surface is different in different solubilities. For water, such as water, its solubility is limited. Due to the mismatch between the degree of molecular solubility and water, water molecules can effectively disperse the molecules. However, in some soluble molecules, such as ethanol, acetone, etc., the solubility phase is good, because there are similar forces in the soluble molecules, and the principle of similar dissolution is followed.
    The density is also one of the physical factors, reflecting the amount of matter in the chemical position. The density depends on the amount of molecules and the density of molecular arrangement. If the molecular weight is heavy and the arrangement is dense, the density is large.
    In addition, this substance may have a specific refractive index, which is the ratio of the sine value of the incident angle of the optical substance to the sine value of the refractive angle, which can reflect the molecular properties and aggregation properties of the substance.
    The above-mentioned physical properties are important for the determination, fractionation, and use of 2-% -1-amino-3- (triethyl) benzene in different domains. Only by mastering its physical rationality can we make better use of this substance.
    Is the chemical properties of 2-chloro-1-nitro-3- (trifluoromethyl) benzene stable?
    The chemical properties of 2-% -1-amino-3- (trifluoromethyl) benzene are uncertain, and it is worth exploring. In this compound, the atomic activity is easy to be reactive. The amino group is a strong nuclear base and can be biochemically combined for many times. Trifluoromethyl compounds have high molecular density due to their fluorine atoms, which cause high molecular density and low molecular activity.
    It is difficult to react to the environment of reaction. If it is acidic medium, amino groups may be reactive, and its nuclear properties are changed. In the environment of reaction, the atom may be taken and lead to the same reaction. And this compound exhibits special reaction activity to oxidizing the original reaction, or because of its special characteristics.
    However, the determination of the chemical properties of 2-%-1-amino-3- (trifluoromethyl) benzene still depends on the reverse properties. Such as degree, solubility, etc., can affect the reverse direction. If the degree of solubility is high, or promote its decomposition; a specific solubility may increase or weaken the molecular force, which affects its qualitative.
    Therefore, the chemical properties of 2-%-1-amino-3- (trifluoromethyl) benzene are determined. It is necessary to consider a number of factors in order to determine the degree of reaction characteristics in different situations.
    What are the preparation methods of 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
    The method of 2-% -1-amino-3- (triacetyl) benzene can be followed as follows:
    The first starting material is benzene, and the nitro group can be introduced. Under the action of the mixed acid of sulfuric acid and nitric acid, the benzene atom on the benzene is replaced by the nitro group to form nitrobenzene. In this step, the reaction rate needs to be controlled. Generally, it is maintained at 50-60 ° C, and it is easy to generate by-products such as polynitrobenzene.
    To obtain nitrobenzene, the original nitro group is reacted to the amino group. With the original acid system, the nitrobenzene is reacted under the appropriate conditions, and the nitro group is gradually reacted to generate the most aniline. During the reaction process, attention should be paid to the acidity and reversal of the reaction system.
    Aniline is then triacetylated. Triacetyl chloride or acetic anhydride can be used. In the presence of catalytic catalysts such as pyridine or triethylamine, the amino group of aniline is triacetylated. In the presence of bioacetylation, the triethyl group is introduced into the amino group position or the amino group position. In addition, 2-% -1-amino-3- (triethyl) benzene can be obtained.
    Another way, nitrotoluene can be produced. First, nitrotoluene is oxidized, and methyl is oxidized to carboxyl groups. High-acid oxidation can be used, and nitrobenzoic acid can be obtained under suitable solution and reaction conditions. Then, as in the original step of nitrobenzene, the nitro group of nitrobenzoic acid is the amino group to obtain aminobenzoic acid. Then a series of inverse groups are introduced, such as the first carboxyl group and the acid chloro group that is easy to reverse, and then the triacetylated phase is introduced, and the triethyl group is introduced to obtain the target.
    Or use other compounds with similar properties as starting materials, follow the basic principle of synthesis, and carefully synthesize the reaction path through the reduction of functional properties, the introduction and elimination of nitrobenzoic acids, so as to form 2-% 1-amino-3- (triethylyl) benzene. In the whole process, it is necessary to control the reaction components in each step, including degree, force, proportion of reaction materials and amount of catalyst, etc., and make good use of the means of extraction to improve the yield of the target materials.
    What are the precautions for storing and transporting 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
    2-% -1-amino-3- (triethyl) indole, this substance is a delicate material. When it is stored in a hot summer sun, it is necessary to pay attention to the eventful situation in order to ensure its stability and avoid accidents.
    The first one is the degree of survival. This compound should be stored in a low environment, usually 2 to 8 degrees Celsius. If the degree is high, it may cause it to dissolve and cause it to decompose or collapse. If you are under the hot summer sun, the ice will melt quickly, and so will this compound. Under the high temperature, it will preserve its original quality.
    The second time, you need to pay attention to the degree of the environment. In the tidal environment, it is easy for the compound to absorb moisture. It absorbs moisture, or causes it to be damaged, or changes its chemical properties. Therefore, if it is not stored, it is better to be dry and clear. It is like an ancient treasure, and it must be dried in a cool place, so as to prevent the material from being invaded.
    Furthermore, it is very important to keep the package in a suitable container, and the container has a good sealing property to prevent leakage. If this compound is leaked, it will not be damaged, and it is more likely to endanger the safety of people in the surrounding environment. In addition to the container, there are also excellent materials to prevent shock and collision. If it is sent to the container, it must be fixed and properly prevented.
    In addition, during the process, avoid oxidation, acid and other substances from being connected. This compound is special, and when the above-mentioned objects meet, it is easy to cause strong reactions and reactions, such as fire and fire, and it will form a large one. Therefore, if it is not easy to do so, it must be separated from this material, and it will be safe to ensure a safe journey.

    In this case, 2-%-1-amino-3- (triethyl) indole should be paid attention to the degree, degree, packaging and avoid the connection of specific objects, etc., so as to ensure its safety and effectiveness.