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What are the main uses of 2-Butoxy-4-Fluoro-1-Methoxybenzene?
2-Butoxy-4-fluoro-1-methoxybenzene, an organic compound, has many uses in chemical synthesis and other fields.
First, in organic synthesis, it is often used as a key intermediate. Because of its specific structure, containing butoxy, fluorine atoms and methoxy groups, it can be combined with other compounds by chemical reactions to build more complex organic molecular structures. Chemists can carefully design reaction paths according to their characteristics to synthesize target compounds required in the fields of medicine, pesticides, materials, etc.
Second, in the field of medicine, or contribute significantly to the synthesis of drugs with specific biological activities. The introduction of fluorine atoms into organic molecules can often significantly change the physical, chemical and biological properties of compounds, such as improving fat solubility, improving drug transmembrane transport ability, and thus enhancing drug efficacy. The compound may be modified and transformed to become a potential drug lead compound, providing an important starting point for the development of new drugs.
Third, in the field of materials science, or used to synthesize materials with special properties. Methoxy and butoxy groups give molecules specific solubility and intermolecular forces, which can be used to prepare materials with special electrical, optical or thermal properties. For example, in organic optoelectronic materials, its unique structure may help to adjust the charge transport and luminescence properties of materials, contributing to the development of organic Light Emitting Diodes (OLEDs), organic solar cells and other devices.
Fourth, it is also useful in the manufacture of fine chemical products. It can be used as a raw material for the synthesis of fine chemicals such as fragrances and dyes. Through chemical reactions, its structure is modified to give products unique fragrance or color characteristics to meet the needs of different industries and consumers.
What are the physical properties of 2-Butoxy-4-Fluoro-1-Methoxybenzene?
2-Butoxy-4-fluoro-1-methoxybenzene is also an organic compound. Its physical properties are particularly important, and it is related to the application of this compound in various scenarios.
Looking at its properties, it is usually a colorless to light yellow transparent liquid under normal conditions. This form makes it easy to mix or separate with other substances in specific process operations. Smell, it has a weak special smell, but this smell is not pungent and unpleasant, and in the general use environment, it will not cause strong stimulation to the human sense of smell.
When it comes to the melting point, its melting point is low and it is often in the low temperature range, causing it to survive in a liquid state at room temperature. The boiling point is relatively moderate. This property can be used in separation and purification methods such as distillation and fractionation, and can be effectively separated from other components by specific temperature control.
In terms of solubility, this compound is soluble in common organic solvents, such as ethanol, ether, acetone, etc. Good solubility in organic solvents makes it able to participate in many chemical reactions as a reactant or solvent in the field of organic synthesis. By means of the medium action of the solvent, the smooth progress of the reaction is promoted, and the reaction efficiency and yield are improved.
The density is slightly smaller than that of water. If mixed with water, it will float on the water surface. This density characteristic is an important guide for the separation and treatment of the aqueous phase in the system, and provides a basis for consideration in the process design of chemical operations.
In addition, the volatility of 2-butoxy-4-fluoro-1-methoxybenzene is weak, and it is not easy to evaporate into the air quickly at room temperature and pressure. This not only ensures the stability of its storage, but also reduces the loss and potential safety risks caused by volatilization during use. These many physical properties are interrelated, which together lay the foundation for its wide application in organic chemistry, materials science and other fields.
What is the chemical synthesis method of 2-Butoxy-4-Fluoro-1-Methoxybenzene?
To prepare 2-butoxy-4-fluoro-1-methoxybenzene, you can follow the following method.
First take 4-fluoro-1,2-dimethoxybenzene as the starting material. Place it in a reactor with an appropriate amount of N, N-dimethylformamide (DMF) as the solvent and stir well. Then, slowly add sodium hydride (NaH). This process requires low temperature and careful operation. Due to the high activity of sodium hydride, it reacts violently in contact with water. Sodium hydride interacts with methoxy active hydrogen in 4-fluoro-1,2-dimethoxybenzene to form the corresponding sodium salt, thereby activating the oxygen atom on the benzene ring and making it easier to participate in the subsequent reaction.
After the reaction system is stabilized, bromobutane (n-C H Br) is added dropwise. The bromine atom in bromobutane has good departure properties, and nucleophilic substitution occurs under the action of the above generated sodium salt. The activated oxygen atom on the benzene ring attacks the α-carbon atom of bromobutane, and the bromine ions leave, forming a carbon-oxygen bond of 2-butoxy-4-fluoro-1-methoxybenzene.
After the reaction is completed, pour the reaction solution into an appropriate amount of ice water to quench the unreacted active reagents such as sodium hydride. The product is then extracted with an organic solvent such as ether, because the product has good solubility in ether. The organic phase is collected and dried with anhydrous sodium sulfate to remove the moisture contained therein.
Finally, the ether and other organic solvents are removed by vacuum distillation, and the corresponding fractions are collected according to the boiling point characteristics of the product to obtain pure 2-butoxy-4-fluoro-1-methoxybenzene. This preparation method has been verified by many practices, and the operation is relatively simple, and the yield is relatively considerable, which can meet the preparation requirements of a certain scale.
What is the price range of 2-Butoxy-4-Fluoro-1-Methoxybenzene in the market?
The price range of 2-butoxy-4-fluoro-1-methoxybenzene in the market is difficult to determine with certainty. This is due to a variety of factors that will affect its price.
First, the source of the material is of great importance. If the raw materials of this product are easy to obtain and sufficient, its price may stabilize and be slightly lower; if the raw materials are scarce, difficult to obtain or complicated to extract, the price will be higher.
Second, the preparation method is also the key. If there is an efficient, convenient and cost-effective preparation process, the cost of producing this 2-butoxy-4-fluoro-1-methoxybenzene can be reduced, which in turn makes the price accessible to the people; on the contrary, if the preparation process is lengthy, requires special equipment or a lot of energy consumption, the price will rise.
Third, the market supply and demand shape the price. If the market faces a strong demand for this product, but the supply is relatively small, the price will rise; if the demand is low and the supply is excessive, the price will fall.
Fourth, regional differences also have an impact. In different places, due to differences in transportation costs, tax policies, etc., the price may vary.
Looking at "Tiangong Kaiwu", it contains all the methods and conditions of things, but it is not as good as this 2-butoxy-4-fluoro-1-methoxybenzene. With common sense, the price of such fine chemicals, or due to the above reasons, ranges from hundreds to thousands of yuan per kilogram, and it is difficult to determine an exact price range.
What are 2-Butoxy-4-Fluoro-1-Methoxybenzene storage conditions?
2-Butoxy-4-fluoro-1-methoxybenzene is one of the organic compounds. Its storage is essential to the quality and safety of the substance, so it cannot be ignored.
When storing this substance, the temperature of the environment is the first priority. It should be placed in a cool place to avoid direct sunlight. When exposed to sunlight, the temperature or sudden rise will cause the compound to change. In summer, when the sun is hot, if it is placed in the sun, it may react due to high temperature and damage its quality. Therefore, it is often stored in a cool place indoors to ensure its stability.
The second is the control of humidity. Moisture may cause the compound to deliquescent, or lead to other side effects. In the south, every rainy season, the air is wet and heavy. If this thing is not properly hidden, it is easy to be invaded by moisture. Therefore, when the storage area is dry, a desiccant can be placed next to it to absorb the moisture around it and protect the purity of the compound.
Furthermore, the choice of container is also heavy. A sealed device must be used to prevent it from connecting with the air. Because of the presence of oxygen in the air, water vapor, etc., or in response to it. If it is stored in a glass bottle, the lid must be tightly sealed to prevent gas from entering. And the material of the device cannot be used with the compound. If the glass is more suitable, it should also be carefully selected in case of special cases.
Also, this material may be dangerous to a certain extent, so the storage place should be kept away from fire and heat sources to prevent explosion. In chemical plants, fire protection is commonly used. When storing this material, this regulation is also followed to ensure the safety of the working place.
In summary, the storage of 2-butoxy-4-fluoro-1-methoxybenzene should be cool, dry, sealed, and protected from fire and heat. According to these items, it can be stored for a long time without changing quality.