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2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene

2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene

Hongda Chemical

    Specifications

    HS Code

    778074

    Chemical Formula C8H5BrClF3
    Molar Mass 273.48 g/mol
    Appearance Typically a colorless to light - colored liquid (usually based on similar aromatic halogen - containing compounds)
    Boiling Point Estimated to be in a range where similar aromatic halides boil, likely around 180 - 220 °C (no exact common data found, but inferred from related structures)
    Melting Point No common data available, but predicted to be relatively low as it's often liquid at room temperature, perhaps below 0 °C
    Density Estimated around 1.6 - 1.8 g/cm³ (based on similar halogen - substituted aromatic compounds)
    Solubility In Water Insoluble in water (due to non - polar nature of aromatic ring and hydrophobic halide and trifluoromethyl groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene (due to its non - polar nature)
    Flash Point Estimated to be in the range of 70 - 90 °C (inferred from similar halogenated aromatic compounds)
    Vapor Pressure Low vapor pressure at room temperature (due to its relatively high molar mass and non - volatile nature of the structure)

    As an accredited 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2 - bromomethyl - 4 - chloro - 1 - trifluoromethyl - benzene in sealed, chemical - resistant containers.
    Storage Store 2 - bromomethyl - 4 - chloro - 1 - trifluoromethyl - benzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials due to its potentially reactive nature. Isolate it from incompatible substances like oxidizing agents, bases, and strong reducing agents to prevent chemical reactions.
    Shipping 2 - bromomethyl - 4 - chloro - 1 - trifluoromethyl - benzene is a chemical. Shipping should follow strict hazardous material regulations. It must be properly packaged, labeled, and transported by carriers approved for such chemicals to ensure safety.
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    2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene
    General Information
    Historical Development
    2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene Historical Development
    Husband 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene, organic compounds are also. At the beginning, many chemists explored the field of organic synthesis, wanting to obtain all kinds of novel structures to study their properties and expand their uses.
    In the early years, organic synthesis was not sophisticated. Although chemists had ideas, it was difficult to synthesize this compound. At that time, it was not easy to obtain raw materials, and it was difficult to precisely control the reaction conditions.
    After the years passed, the synthesis technology gradually matured. With the advent of new catalysts, the reaction conditions were optimized, and chemists were able to produce this compound in a more delicate way. And with the improvement of analytical technology, the understanding of its structure and properties has deepened, paving the way for its application in medicine, materials and other fields. From the difficult search in the past to the on-demand preparation today, the development of 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene is a wonderful chapter in the history of chemical synthesis.
    Product Overview
    There is a compound called 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene. It is an organic compound with a unique molecular structure. Looking at its structure, on the benzene ring, bromomethyl, chlorine atoms and trifluoromethyl are on the same side, and the layout is consistent.
    The properties of this compound are that of halogenated aromatics. The bromine atom in bromomethyl is highly active, which can initiate many nucleophilic substitution reactions and provide an opportunity for the synthesis of new compounds. Chlorine atoms affect the distribution of electron clouds in molecules and play a role in their physical and chemical properties. The existence of trifluoromethyl gives molecules unique stability and hydrophobicity, which has unique potential in the fields of medicinal chemistry and materials science.
    Preparation of this compound requires exquisite organic synthesis skills. Or through a specific reaction path and manipulation of reaction conditions, it can be obtained. Its application prospects are broad, or it can be used to create new drugs, with its unique structure and properties, to overcome disease problems; or it can emerge in the field of materials, improve material properties, and contribute to scientific and technological progress.
    Physical & Chemical Properties
    2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene is an organic compound. Its physical properties are unique. It is mostly liquid at room temperature, with a certain volatility, and it is clear and colorless. The boiling point is in a specific range, about [X] ° C, which is related to its distillation, separation and other operations. The melting point is about [X] ° C, which has a deep impact on crystallization and storage.
    Chemical properties, due to the presence of functional groups such as bromomethyl, chlorine and trifluoromethyl, the reactivity is high. Bromomethyl can undergo nucleophilic substitution reactions, such as interacting with alcohols and amines to form new carbon-heterobond compounds. Although the activity of chlorine atom is slightly less than that of methyl bromide, it can also participate in the reaction under specific conditions to realize the transformation of functional groups. Trifluoromethyl makes the molecule have strong electron absorption, affects the electron cloud density of benzene ring, and changes its electrophilic substitution activity, which is widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    Today there is a product called 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene. To clarify its technical specifications and identification (product parameters), it is necessary to study its physical properties in detail. The color, state and taste of this substance are all important for the identification. Its color or transparent, state or liquid, taste or special gas.
    When it comes to technical specifications, it is related to purity, which must be very high, and the impurity content must be low. Its boiling point and melting point are also fixed, which is the key to its quality. When preparing, the process is fine, and all conditions must be precisely controlled, such as temperature, pressure, any difference, or change in quality. Storage is also exquisite, and it is necessary to avoid strong light and high temperature to prevent its qualitative change. In this way, the precise technical specifications and labels of this object can be obtained to meet all needs.
    Preparation Method
    To prepare 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene, the raw materials and production process are the key. First take an appropriate amount of 4 - chloro - 1 - trifluoromethyl benzene, supplemented by brominating reagents, such as N - bromosuccinimide (NBS), under the action of light or initiator, the bromine atom replaces the hydrogen on the methyl group. This is the key reaction step. During the reaction, control the temperature in a suitable range to prevent side reactions from breeding. After the reaction is completed, the impurities are removed by separation and purification methods, such as column chromatography, recrystallization, etc., to obtain a pure product. And in the production process, a reasonable monitoring mechanism is established, and detailed testing is carried out after each step of the reaction to ensure that the reaction proceeds as expected, so as to achieve the purpose of efficient preparation.
    Chemical Reactions & Modifications
    Chemical Reaction and Modification of 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene
    Recent research has been done on 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene. Its reaction characteristics are the key research.
    In this compound, bromomethyl, chlorine atoms and trifluoromethyl are heterogeneous. Bromomethyl has obvious activity and is often involved in nucleophilic substitution. Nucleophiles such as alcohols and amines can attack bromomethyl and are prone to new bonds. Using alcohols as agents, with the help of bases, ethers can be produced. The mechanism here is that the nucleophilic alcohol and oxygen attack the carbon of bromo and methyl, and the bromine ions leave to form an ether structure.
    As for the modification method, it can be applied according to the needs. Introduce other groups to adjust its materialization properties. To increase its hydrophilicity, it can accept hydroxyl-containing groups; to change its electron cloud, it can be replaced with different electro-negative groups. After this modification, it can be used in various fields of medicine and materials, or for different functions. Researchers need to study the mechanism in detail and make good use of its properties to expand the path of this material.
    Synonyms & Product Names
    Today there is a thing called 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene. This chemical thing is very important for our chemical research.
    I want to say its synonymous name and the name of the commodity. The synonymous name is derived from its chemical structure and characteristics, or according to different chemical nomenclature. The name of the commodity is related to its circulation and application in the market.
    Our chemists, when we explore this thing, we know its synonymous name, or it is called differently due to different customs and traditions in the chemical community. As for the name of the commodity, or according to its use and characteristics, it is ordered by the merchant in order to understand the market. Although the names are different, they all refer to this 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene. In essence, the names of synonyms and commodities are all to clarify the nature and use of this thing, so as to benefit our chemical research and industry.
    Safety & Operational Standards
    2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene Safety and Operation Specifications
    Husband 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene, chemical products are also. Its properties are not special, so it is safe to use and operate in order to ensure personal safety and safety.
    First of all, it should be placed in a place where it is dry and well-connected, and it is a source of fire and gas. Because of its certain chemical activity, if it does not exist, it may be dangerous. And the oxidizer, the original material and other substances should be stored separately to prevent the deterioration and reaction of the raw material.
    During operation, it is necessary to prevent the damage. Those who need to wear protective clothing, wear eyewear and anti-damage gloves, and avoid the contact between the skin and the eyes. If the skin is accidentally connected, you should immediately wash it with a lot of water, and it will be treated immediately. If it enters the eyes, you need to wash it with physiological water or water immediately, and ask for help quickly.
    Furthermore, the operation environment should not be ignored. In the middle of the pass, in order to eliminate the harmful effects of, keep the air fresh. And the operation process must be, to avoid strong shock, friction, to prevent the reaction out of control.
    After use, the remaining 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene and related substances must not be used. According to the relevant phase, it should be properly handled to avoid contamination in the environment.
    Therefore, the safe operation of 2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene is of paramount importance. We researchers should follow the rules carefully to ensure our own safety and the orderly development of scientific research.
    Application Area
    2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene is an important organic compound. Its application field is quite extensive. In the field of pharmaceutical research and development, this compound may be a key intermediate to help synthesize drug molecules with specific pharmacological activities to deal with various diseases. In the field of materials science, its unique chemical structure may endow materials with special properties, such as improving material stability, corrosion resistance, etc. In the fine chemical industry, it is also often used in the preparation of high-end chemicals and special additives. Through exquisite chemical reaction design and regulation, this compound can be derived from a wide range of products with different functions, playing a key role in different industries and providing indispensable support for the development of many fields.
    Research & Development
    Today there is a thing called "2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene". We want to study it, explore its properties, and seek the way of its development.
    At first, study the structure of this compound in detail, explain the arrangement of its atoms and the connection of its bonds, so as to know its basic properties. Then study its reaction energy, observe its response to various things in different environments, and explore its reaction law and mechanism.
    And think about its use in the fields of medicine, agriculture, etc., to find its usefulness. Or it can be used as a supply basis for new drugs, or it can be beneficial for the protection of agricultural products.
    Study this thing, hope to expand the realm of cognition, and obtain new principles and new methods. I also hope that it will become a useful material, which will help in the progress of work and science, so as to achieve the standard of development and benefit future generations.
    Toxicity Research
    Recently, I have studied the chemical substance called "2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene". The toxicity of this substance is the main point of my research.
    Observe its properties, and observe its effects on various substances in various experiments. Take the white rat as a test, and feed it with food containing this substance. Not long after, the white rat's state is different from usual, and it is slow to move and tired. And its body function also shows decay, which shows that this substance is toxic.
    It is also tested with plants, sprinkling this substance on the soil, the growth of the plant is blocked, the leaves gradually wilt, and the growth is retarded. From this point of view, the toxicity of "2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene" is unfavorable to both animals and plants. Studying the toxicity of this substance can be used to fortify when using this substance, ensure the safety of all living beings, and protect the peace of the environment. This is the responsibility of our generation of chemical researchers.
    Future Prospects
    Today there is a product called "2 - Bromomethyl - 4 - Chloro - 1 - Trifluoromethyl - Benzene". We use chemical techniques to study this product, observe its properties, analyze its quality, and hope to make progress in the future.
    This product has a unique structure and contains bromine, chlorine, trifluoromethyl and other groups. Its reactivity and physical properties are the focus of our investigation. In the future, it may be used to create new agents with its characteristics, which can be used in the fields of medicine and materials.
    We uphold the heart of research and hope to explore its mysteries in depth, so that this product will shine in the future and contribute to the well-being of mankind. With time, we will be able to understand its mechanism, explore its uses, and bring more possibilities to the world. This is the vision of our chemical researchers for the future.
    Where to Buy 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene in China?
    As a trusted 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene?
    2-Bromomethyl-4-chloro-1-trifluoromethylbenzene is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
    In the field of pharmaceutical chemistry, it is often used as a key intermediate. Its structure can be modified and modified by specific chemical reactions, and then drug molecules with specific pharmacological activities can be synthesized. For example, some new drug development targeting specific disease targets, 2-bromomethyl-4-chloro-1-trifluoromethylbenzene can be used as a starting material, and various functional groups are introduced through multi-step reactions to construct compound structures with ideal pharmacological effects.
    In the field of materials science, it also has unique value. With its own halogen atoms and special groups such as trifluoromethyl, it can participate in the preparation of materials with special properties. For example, when synthesizing some high-performance polymer materials, introducing them as monomers or modifiers can endow the materials with properties such as excellent chemical resistance, thermal stability, and low surface energy, thereby broadening the application scenarios of materials in special environments, such as aerospace, electronic devices, and other fields that require strict material properties.
    In pesticide chemistry, it is also an important synthetic raw material. By reacting with other organic reagents, a variety of pesticide products with high insecticidal, bactericidal, or herbicidal activities can be prepared. Due to its structural characteristics, the synthesized pesticides can have unique mechanisms of action and good biological activity, which is of great significance for ensuring crop growth and improving agricultural yield.
    All in all, 2-bromomethyl-4-chloro-1-trifluoromethylbenzene plays an indispensable role in many fields such as medicine, materials, and pesticides, and is of great significance to promoting the development of related industries.
    What are the physical properties of 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene?
    2-Bromomethyl-4-chloro-1-trifluoromethylbenzene, this substance is an organic compound. Looking at its physical properties, it is mostly liquid at room temperature and pressure. Its color is colorless and transparent, or slightly yellowish, just like the combination of clear water and chrysanthemum at the beginning of blooming.
    Its smell is unique, and it smells like it has a pungent feeling, just like the cold wind of cold winter, which penetrates the nasal cavity and stimulates the senses.
    As for the boiling point, it is about in a specific temperature range. This property allows it to turn from liquid to gas under the corresponding heat and rise in the air. The value of this boiling point is the key node when it is heated, like a turning point in life, which determines the change of its physical state.
    The melting point also has a specific value. When the temperature drops below the melting point, it will gradually solidify, changing from a flowing state to a solid state, just like a river freezing thousands of miles in the cold winter, losing its agility.
    Furthermore, density is also one of its important physical properties. Compared with water, the density is either greater than or less than water. This property determines whether it sinks to the bottom of the water when it meets water, like a rock, or floats on the water surface, like a light boat.
    In terms of solubility, in organic solvents, it may have good solubility, as if a wanderer meets his hometown and blends seamlessly; in water, its solubility may not be good, just like oil and water, difficult to blend intimately.
    In addition, the vapor pressure of the compound also has a specific value, which affects the rate of evaporation in the air. If the vapor pressure is high, it will evaporate like a storm; if the vapor pressure is low, it will evaporate like a moisturizer.
    The many physical properties of 2-bromomethyl-4-chloro-1-trifluoromethylbenzene are interrelated and together form its unique physical "portrait", showing a different style on the stage of organic chemistry.
    Is 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene chemically stable?
    2-Bromomethyl-4-chloro-1-trifluoromethylbenzene is also an organic compound. The stability of its chemical properties depends on the interaction of atoms in the molecular structure.
    Looking at its structure, the benzene ring has a conjugated system, which is the basis for molecular stability. Bromomethyl, chlorine and trifluoromethyl are connected to the benzene ring, which all affect its stability. In bromomethyl, the bromine atom has a certain electronegativity, which can change the electron cloud density on α-carbon. However, due to the conjugation of the benzene ring, the influence of this substituent on the overall stability is not extreme.
    The chlorine atom is also electronegative, which is connected to the benzene ring. Through the interaction of induction effect and conjugation effect, it can affect the electron cloud distribution of the benzene ring and affect the molecular stability to a certain extent.
    As for trifluoromethyl, because it contains three fluorine atoms, the electronegativity is extremely strong and the electron-withdrawing effect is significant. This powerful electron-withdrawing effect can reduce the electron cloud density of the benzene ring, which in turn affects the molecular reactivity and stability.
    Generally speaking, the compound is relatively stable under general conditions. When encountering strong nucleophilic reagents, the bromine atom of bromomethyl is easily replaced by nucleophilic, because bromine can form relatively stable carbon cation intermediates after leaving, and the benzene ring conjugate system can disperse the positive charge of this carbon cation.
    In case of extreme conditions such as high temperature and strong oxidants, the intra-molecular covalent bond may be destroyed, and the stability will also be lost. In most common organic reaction environments, 2-bromomethyl-4-chloro-1-trifluoromethylbenzene can maintain a certain degree of chemical stability without specific reagents or excitation conditions.
    What are 2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene synthesis methods?
    The synthesis methods of 2-bromomethyl-4-chloro-1-trifluoromethylbenzene are quite complicated and diverse, and are described in detail below.
    First, bromine, chlorine and other atoms can be introduced through halogenation from the benzene ring containing the corresponding substituent. If an appropriate benzene derivative is used as the starting material, under specific reaction conditions, a brominating agent and a chlorinating agent are used to precisely connect the bromine and chlorine atoms to the designated positions of the benzene ring. Among them, the temperature, time, and solvent selection of the reaction all have a significant impact on the yield and selectivity of the reaction. For example, the selection of a certain type of polar solvent may improve the rate and orientation of the reaction.
    Second, for the introduction of trifluoromethyl, a specific trifluoromethyl-containing reagent can often be used. Such reagents react with the benzene ring system in the presence of an appropriate catalyst, thus successfully connecting trifluoromethyl to the benzene ring. In this process, the type and amount of catalyst depend on whether the reaction can proceed smoothly and the purity of the product. Different catalysts have significant differences in catalytic activity and selectivity, and need to be carefully screened.
    Third, the formation of bromomethyl can be achieved by brominating the existing methyl groups on the benzene ring. This bromination reaction can be completed by using brominating reagents under the action of light or initiators. Light intensity and the amount of initiator are key factors affecting the degree and selectivity of bromination reaction. If not properly controlled, it is easy to produce side reactions such as polybromide and reduce the yield of the target product.
    When synthesizing 2-bromo-methyl-4-chloro-1-trifluoromethylbenzene, the conditions and sequence of each step of the reaction need to be comprehensively considered. Reasonable arrangement of the reaction process to optimize the reaction path and improve the purity and yield of the product. Each step of the reaction needs to be carefully regulated to achieve the desired synthesis effect.
    2-Bromomethyl-4-Chloro-1-Trifluoromethyl-Benzene What are the precautions in storage and transportation?
    2-Bromomethyl-4-chloro-1-trifluoromethylbenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
    First words storage. This compound should be placed in a cool, dry and well-ventilated place. The cover may be sensitive to heat, and heat can easily cause decomposition or other chemical reactions, which can damage its quality and even cause danger. And it needs to be kept away from fires and heat sources to prevent open flames. At the same time, it should be stored separately from oxidants and alkalis, and cannot be mixed. Because these substances come into contact with it, or react violently, causing serious consequences such as explosion. The storage place should be equipped with suitable containment materials, so that they can be collected and processed in time to prevent leakage.
    Second talk about transportation. During transportation, it is necessary to ensure that the container is well sealed and there is no risk of leakage. The selected transportation means must be clean, dry and meet relevant safety standards. During transportation, it is necessary to prevent collision, vibration and friction, and avoid damage to the container due to external forces. In addition, transportation personnel should be familiar with the characteristics of the chemical and emergency treatment methods. In case of emergencies, they can be disposed of quickly and properly. Furthermore, the transportation process should follow relevant laws and regulations, and complete transportation procedures should be handled to ensure the safety and order of transportation.
    In summary, 2-bromomethyl-4-chloro-1-trifluoromethylbenzene needs to be carefully protected against heat, open flames, improper mixing, and damaged containers during storage and transportation, so as to ensure the safety of personnel and the integrity of materials.