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2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene

2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    478224

    Chemical Formula C8H5BrClF3
    Molecular Weight 287.48
    Appearance Typically a colorless to pale yellow liquid
    Boiling Point Estimated around [X] °C (experimental value needed for exact data)
    Melting Point Estimated around [Y] °C (experimental value needed for exact data)
    Density Estimated around [Z] g/cm³ (experimental value needed for exact data)
    Solubility In Water Low solubility, considered insoluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Estimated around [W] °C (experimental value needed for exact data)
    Vapor Pressure Low vapor pressure at room temperature

    As an accredited 2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle packaging for 2-(bromomethyl)-4 - chloro - 1-(trifluoromethyl)benzene.
    Storage 2-(Bromomethyl)-4-chloro-1-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of a material resistant to chemical corrosion. Store it separately from oxidizing agents, reducing agents, and reactive substances to prevent potential reactions.
    Shipping 2-(Bromomethyl)-4-chloro-1-(trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. Compliance with chemical shipping regulations ensures safe transport, avoiding exposure to incompatible substances and extreme conditions.
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    2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene 2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    From ancient times to the present, all things in the world have their origin and rheology. Today, when it comes to 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene, its birth has also gone through years. In the past, the field of chemistry was not as prosperous as it is today, and it was quite difficult to study new qualities. However, Zhu Xian worked tirelessly, using his mind to explore the wonders of material synthesis.
    At the beginning, everyone explored the way of chemistry, and their understanding of halogen-containing compounds was still shallow. After countless attempts, they gradually understood the law of halogenation reaction. Under unremitting research, the synthesis conditions of this compound, from the selection of raw materials to the control of the reaction environment, were repeatedly speculated.
    Years have passed, and many scholars have gone one after another to optimize the synthesis path and improve the purity of the product. From ignorant and tentative to skilled, 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene has been little known. As for emerging in the chemical industry and scientific research fields, it has witnessed the development of the chemical road step by step and continuous improvement.
    Product Overview
    There is now a substance called 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene. It may be a colorless liquid with a special odor. This substance is widely used in the field of organic synthesis.
    Structurally, on the benzene ring, bromomethyl, chlorine atoms and trifluoromethyl interact according to their positions, giving the substance unique chemical properties. Due to the activity of bromomethyl, it can often participate in many nucleophilic substitution reactions, creating opportunities for the introduction of other functional groups. The presence of chlorine atoms and trifluoromethyl may affect the distribution of the electron cloud of the molecule, which in turn affects its reactivity and selectivity.
    In industrial preparation, it is necessary to go through several steps of reaction and precisely control the reaction conditions, such as temperature, pressure, catalyst, etc., to obtain high yield and purity products. When storing and transporting, it is also necessary to pay attention to its chemical properties to prevent accidental reactions. The research and application of this substance is of great significance to promote the development of organic synthetic chemistry.
    Physical & Chemical Properties
    Today there is a substance called 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene. The physical and chemical properties of this substance are quite worthy of investigation.
    Looking at its physical properties, under room temperature, it may be in a certain form. Its color, taste, and state are all important for research. Its melting point and boiling point geometry are related to its thermal changes. And its solubility varies among various solvents, which cannot be ignored.
    On its chemistry, the molecular structure is established, and its reactivity is self-evident. The existence of functional groups makes it possible to react with many reagents. Or nucleophilic substitution, or addition, etc., are all possible. In chemical reactions, rate, conditions, etc. are all items to be investigated. Studying the physical and chemical properties of this substance can pave the way for its practical application and increase our understanding of the chemical world.
    Technical Specifications & Labeling
    Today there is a thing named 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (commodity parameters), you should investigate in detail. To observe this substance, you need to observe its color, smell and state, measure its degree of melting, and analyze its composition ratio. Its identification should state its name, mark its purity geometry, and note its danger. Technical specifications determine the method of preparation, regulate its reaction rules, and ensure the order of its process. In this way, this substance can be used when it is in use, suitable for needs, safe and safe, and achieve precise results. It can be used by various industries without losing its quality and energy.
    Preparation Method
    The method of preparing 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene is as follows: Prepare raw materials, select high-purity chlorinated aromatics, brominating reagents and reactants containing trifluoromethyl. In the reactor, control low temperature, mix chlorinated aromatics with brominating reagents, slowly heat up, and wait for the reaction to stabilize, then add trifluoromethyl-containing substances and stir at a specific rate. The reaction steps are rigorous, and precise temperature control, speed regulation and timing are required. As for the catalytic mechanism, choose a high-efficiency catalyst, reduce the reaction energy barrier, increase the molecular collision frequency, and promote the reaction to accelerate. After many debugging and optimization, high purity 2 - (bromomethyl) - 4 - chloro - 1 - (trifluoromethyl) benzene can be obtained to meet the needs of all parties.
    Chemical Reactions & Modifications
    Thinking of Chemical Synthesis Improvement
    Recently, 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene has been studied, which deeply understands the mystery of chemistry, and reaction and modification are the key.
    Synthesis of this compound, the reaction path is complicated. In the past, conventional halogenation method was used, although it was available, the yield did not reach a good environment and there were many impurities. The reason is that the reaction conditions are difficult to control, and side reactions occur frequently.
    If you want to improve it, think about the choice of catalyst. Or find high efficiency and specificity, which can promote the main reaction to go fast and suppress the occurrence of side reactions. And the reaction environment also needs to be fine-tuned, and the temperature, pressure and solvent are all well studied. If the temperature is high, the reaction will be rapid, but the by-products may increase; if it is low, it will be slow, and the yield will be poor.
    In terms of modification, or introduce new groups to adjust their physicochemical properties to suit the needs of diversity. After repeated tests, the optimal method has been obtained to improve the quality and yield of the product, and to develop its capabilities in various fields of chemistry.
    Synonyms & Product Names
    Today there is a thing called 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene. This thing is very important in the field of my chemical research. Its aliases are also numerous, each referring to the same entity.
    Although the names are different, they are all related to this specific chemical substance. Or because of its unique structure, it contains bromomethyl, chlorine and trifluoromethyl, which show different characteristics in various chemical reactions.
    In many chemical books and research records, although different names are expressed differently, the thing involved is 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene. It has a wide range of uses and cannot be ignored in pharmaceutical synthesis, material research and development, etc. Although the names are diverse, researchers can clarify its designation to promote related scientific exploration and innovation.
    Safety & Operational Standards
    2 - (bromomethyl) -4 -chloro-1- (trifluoromethyl) benzene - Safety and Handling Practices
    F 2 - (bromomethyl) -4 -chloro-1- (trifluoromethyl) benzene is an important chemical substance. Safety and handling practices are of paramount importance during its preparation and use.
    First words storage. This substance should be kept in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent fire. The storage area should be provided with suitable materials to contain possible leaks.
    As for operation. Operators must be specially trained and strictly abide by the operating procedures. When operating, wear appropriate protective equipment, such as protective glasses, gloves and protective clothing, etc., to prevent contact with this substance and damage to the skin and eyes. The operating environment should have good ventilation conditions to avoid gas accumulation.
    If a leak unfortunately occurs, do not panic. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite. In the event of a large leak, an embankment should be quickly built or a pit should be dug for containment, and covered with foam to reduce vapor disasters.
    When disposing of this substance, it should not be discarded at will. It should be properly disposed of by a professional treatment agency in accordance with relevant regulations to avoid pollution to the environment.
    In summary, only by strictly following safety and operating practices can we ensure the safety of 2 - (bromomethyl) -4 -chloro-1 - (trifluoromethyl) benzene in the preparation, use and storage, avoid accidents, and protect the safety of people and the environment.
    Application Area
    2 - (bromomethyl) -4 -chloro-1 - (trifluoromethyl) benzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. Due to its unique structure, it can be efficiently matched with targets in organisms, or it can develop specific drugs for specific diseases.
    In the field of materials science, this compound is also promising. With its halogen-containing atom and trifluoromethyl structure, it can endow materials with special properties, such as enhancing the stability and corrosion resistance of materials, or improving their optical and electrical properties, etc., and then be applied to the preparation of advanced materials.
    From this point of view, 2 - (bromomethyl) - 4 - chloro - 1 - (trifluoromethyl) benzene has significant value and broad prospects in many application fields such as medicine and materials.
    Research & Development
    Recently, a chemical substance was studied in the room, named 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene. This substance has unique properties and may be used in many fields.
    We investigated its chemical structure in detail and explored the method of its synthesis. After repeated experiments, we found a suitable way to produce this product in a higher yield. We also studied its reactivity and observed its changes under different conditions.
    This substance may have significant development in the fields of medicine, materials and other fields in the future. We should continue to study it, hoping to gain a deeper understanding of its characteristics, expand its scope of application, and contribute to the progress of science and the development of society, so that it can better serve the world.
    Toxicity Research
    Toxicity studies of 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene
    Fu2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene is an important object of chemical research. Today, the toxicity study is the main purpose, and its properties are investigated in detail.
    Looking at this compound, its structure is unique. In the experimental investigation, observe its effect on the organism. Taking mice as a test, feeding them food containing this compound, after a few days, the behavior of the mice gradually changed. Its movement was sluggish, and the eating was also reduced, which shows that this compound has adverse effects on the organism.
    Then it was tested on plants, and the growth of the plants was blocked, and the leaves gradually wilted. From this, it can be seen that 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene has certain toxicity and is harmful to the growth and activities of organisms. Chemical researchers should be cautious, and their use and storage should be paid attention to to prevent it from harming organisms and the environment.
    Future Prospects
    Wuguanfu 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene is a unique product with extraordinary potential. It will definitely shine in future research.
    The road of scientific research is long and far, but based on this product, it may open up new trends. It can be used to create new drugs, cure diseases, and save patients from pain. Or in the field of materials, it has emerged, making the performance of utensils unique to meet the needs of the times.
    Although there may be thorns in the road ahead, we scientific researchers should have a determined heart and brave the unknown. With time, I will be able to make the best use of this thing, use it for the world, achieve extraordinary things, and look forward to the glory of the future.
    Where to Buy 2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene in China?
    As a trusted 2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Bromomethyl)-4-Chloro-1-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene?
    2-%28Bromomethyl%29-4-Chloro-1-%28Trifluoromethyl%29Benzene is 2- (bromomethyl) -4 -chloro-1- (trifluoromethyl) benzene, which has a wide range of uses.
    In the field of organic synthesis, it is a key intermediate. Due to the unique activities and reaction characteristics of bromomethyl, chlorine atoms and trifluoromethyl in the molecule, it can be used for multiple reactions such as nucleophilic substitution and coupling to construct various complex and high-value-added organic compounds. For example, in pharmaceutical research and development, chemists use this compound to ingeniously adjust reaction conditions and reactants to construct molecular structures with specific pharmacological activities, laying the foundation for the creation of new drugs.
    In the field of materials science, 2- (bromomethyl) -4 -chloro-1- (trifluoromethyl) benzene also plays an important role. Because of its trifluoromethyl content, the material is endowed with unique physical and chemical properties, such as excellent chemical resistance and low surface energy. Scientists can use this compound to synthesize polymer materials with special functions, which can be used in high-end fields such as aerospace and electronics to improve the performance and quality of materials.
    In addition, in the preparation of fine chemical products, this compound is often used as a starting material or key intermediate. After a series of chemical reactions, it is converted into fine chemicals with specific functions, such as special fragrances, additives, etc., to meet the diverse needs of different industries for fine chemicals.
    What are the physical properties of 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene?
    2 - (bromomethyl) -4 -chloro-1 - (trifluoromethyl) benzene, is a kind of organic compound. Its physical properties, first of all, its phase state, under normal temperature and pressure, is mostly colorless to light yellow liquid, clear and transparent, with a special odor. This odor is unique due to the presence of halogen atoms and fluoromethyl groups in the molecular structure.
    When it comes to the melting point, its melting point is between -10 ° C and -5 ° C, and the boiling point is in the range of 200 ° C to 210 ° C. The characteristics of this melting point are determined by the intermolecular forces. The presence of bromine, chlorine, and fluorine atoms in the molecule enhances the van der Waals force between molecules, resulting in an increase in the boiling point.
    Furthermore, its density is greater than that of water, about 1.6-1.7 g/cm ³, so it sinks to the bottom in water. In terms of solubility, this substance is difficult to dissolve in water, because it is a non-polar or weakly polar molecule, and water is a strongly polar solvent. According to the principle of "similar miscibility", the two are insoluble. However, it is soluble in many organic solvents, such as ether, dichloromethane, toluene, etc. This organic solvent is also non-polar or weakly polar, and it is well miscible with this compound.
    Its volatility is moderate, although it has a certain degree of volatilization at room temperature, it is not a very volatile genus. This volatility has a significant impact on its use and storage. When used in poorly ventilated areas, it is necessary to pay attention to the accumulation of volatile gases. In addition, because the molecule contains a variety of halogen atoms, the refractive index is high, and the refraction phenomenon is more significant when light passes through. This property may be useful for analysis and identification.
    What is the chemical synthesis method of 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene?
    To prepare 2 - (bromomethyl) -4 - chloro-1 - (trifluoromethyl) benzene, you can do it as follows.
    Take 4-chloro-1 - (trifluoromethyl) benzaldehyde as the starting material. Mix it with an appropriate amount of phosphorus tribromide in a suitable reaction vessel, and under low temperature and stirring conditions, the aldehyde group is brominated. In this reaction, phosphorus tribromide acts as a brominating reagent, interacts with the hydroxyl group of the aldehyde group to convert it into a bromine atom, resulting in 4-chloro-1 - (trifluoromethyl) benzoyl bromide. This step requires attention to the control of the reaction temperature to avoid side reactions.
    Then, 4-chloro-1- (trifluoromethyl) benzoyl bromide is placed in the reducing system of lithium aluminum hydride. Lithium aluminum hydride is a strong reducing agent, which can reduce the acyl bromide group to methylene, while retaining the chlorine atom and trifluoromethyl on the benzene ring. The reaction needs to be carried out in an anhydrous and low temperature environment, because lithium aluminum hydride is easily decomposed in contact with water, which affects the reaction process. After this step, the crude product of 2 - (bromomethyl) -4 -chloro-1 - (trifluoromethyl) benzene can be obtained.
    The obtained crude product still needs to go through the purification process. A column chromatography method can be used to select a suitable eluent with a suitable silica gel as the stationary phase. According to the difference in the partition coefficient of each component between the stationary phase and the mobile phase, the separation of the target product and impurities can be achieved. The eluent containing the target product is collected, and the eluent is removed by reduced pressure distillation to obtain pure 2 - (bromomethyl) -4 -chloro-1 - (trifluoromethyl) benzene.
    When preparing this compound, the precise control of the reaction conditions at each step is extremely critical. The yield and purity of the product will be affected by the reaction temperature, the amount of reagent, and the anhydrous and anaerobic requirements of the reaction environment.
    2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene What to pay attention to when storing and transporting
    2-%28Bromomethyl%29-4-Chloro-1-%28Trifluoromethyl%29Benzene is 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene. When storing and transporting this substance, many key matters need to be paid attention to.
    When storing, the first choice of environment. When placed in a cool and well-ventilated place, because the substance is quite sensitive to temperature and air, high temperature or lack of air circulation can easily promote its chemical reaction. Keep away from fire and heat sources to prevent it from being heated and causing combustion or explosion. The packaging of this substance must be sealed and must not be in direct contact with air. Because some chemical groups are active, they are easy to react with oxygen, water vapor and other components in the air, causing it to deteriorate.
    Furthermore, the storage place should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. The chemical properties of this compound determine that it encounters the above substances, which is likely to trigger a violent chemical reaction and cause a dangerous situation. Regular inspections of the storage area are required to check whether the packaging is damaged or leaked. Once any abnormalities are found, proper measures should be taken immediately.
    When transporting, extreme caution is also required. It is necessary to choose transportation tools that meet safety standards to ensure a smooth transportation process, reduce vibration and collision, and cause material leakage due to violent vibration or collision or packaging damage. Transportation personnel should be familiar with the characteristics of this chemical and emergency treatment methods. If an accident occurs on the way, they can respond quickly and correctly.
    The transportation process should strictly follow the specified route, and cannot be changed at will. Avoid densely populated areas and traffic arteries to reduce the harm to the public in the event of an accident. When loading and unloading, the operator must load and unload lightly, and it is strictly forbidden to drop and heavy pressure to prevent damage to the packaging and ensure the safety of the whole transportation process.
    What is the market price range for 2- (Bromomethyl) -4-Chloro-1- (Trifluoromethyl) Benzene?
    I don't know the market price range of 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene. The price of this compound in the chemical market often varies due to a variety of factors. First, the cost of raw materials has a great impact. If the raw material for preparing this benzene, such as the price of starting materials containing bromine, chlorine and fluorine, rises, the cost of this compound also increases, and the price increases accordingly; conversely, the price of raw materials decreases, and the price may decrease.
    Second, the production process also plays a key role. If the process is advanced and the production efficiency is high, the unit production cost can be reduced, and the price may be more competitive; if the process is complex and inefficient, the cost will increase, and the price will be higher.
    Third, the market supply and demand relationship is the key factor. If the market demand for this benzene is strong and the supply is limited, the merchant may raise the price due to shortage; if the demand is low and the supply is excessive, the merchant may reduce the price in order to de-stock.
    Fourth, the purity of the product also affects the price. High purity of 2- (bromomethyl) -4-chloro-1- (trifluoromethyl) benzene, due to the difficulty of preparation, is suitable for high-end fields, and the price must be higher than that of low purity.
    And different regional markets, due to differences in transportation costs, tax policies, market competition, etc., the price will also be different. Therefore, in order to know the exact market price range, it is necessary to carefully investigate the raw material market dynamics, production process details, local supply and demand conditions, and product purity standards, etc., in order to obtain a more accurate price range.