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2-(Bromomethyl)-3,4-Difluoro-1-Methoxybenzene

2-(Bromomethyl)-3,4-Difluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code

337008

Chemical Formula C8H7BrF2O
Molecular Weight 237.04
Appearance Solid (predicted)
Boiling Point Unknown
Melting Point Unknown
Density Unknown
Solubility In Water Insoluble (predicted)
Flash Point Unknown
Vapor Pressure Unknown
Refractive Index Unknown
Packing & Storage
Packing 100g of 2-(bromomethyl)-3,4 - difluoro - 1 - methoxybenzene in sealed chemical - grade packaging.
Storage Store 2-(bromomethyl)-3,4 -difluoro-1-methoxybenzene in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of glass or a suitable chemical - resistant material. Due to its reactivity, store it separately from oxidizing agents, bases, and nucleophiles to prevent unwanted reactions.
Shipping 2-(Bromomethyl)-3,4 -difluoro-1 -methoxybenzene is shipped in accordance with chemical transportation regulations. Packed securely in appropriate containers, it's transported under controlled conditions to ensure safety during transit.
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2-(Bromomethyl)-3,4-Difluoro-1-Methoxybenzene 2-(Bromomethyl)-3,4-Difluoro-1-Methoxybenzene
General Information
Historical Development
Throughout the ages, chemical substances have been valued by the academic community. In today's words 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene this compound, its birth can also be traced. In the past, chemists worked hard to explore the field of organic synthesis. After repeated experiments and research, this result was obtained. At the beginning, it only existed in the idea of theory, and after countless attempts, it improved the reaction conditions and optimized the synthesis path. From the selection of raw materials to the grasp of reaction temperature and duration, all strive for excellence. Today, this compound has become an important material for chemical research, emerging in many fields such as medicine and materials. In the future, it is expected to open up more new frontiers and write more brilliant chapters.
Product Overview
2 - (bromomethyl) - 3,4 - difluoro - 1 - methoxybenzene is also the chemical I studied. Its shape may be a colorless liquid with a special odor. Among this compound, the structure of bromomethyl, difluoro and methoxy groups is particularly critical. Bromomethyl has high activity and may provide a lively check point for reactions during organic synthesis, so as to facilitate the construction of various compounds. The introduction of difluorine atoms may change the physical and chemical properties of the compound, such as its solubility and stability. The presence of methoxy groups also affects the electron cloud distribution of the compound, which is related to its reactivity and selectivity. This compound may have potential application value in the field of organic synthesis, providing an important foundation for the creation of novel drugs and materials.
Physical & Chemical Properties
Today there is a thing called 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene. Its properties are related to the principle and transformation of things. View its shape, or a body with pure color and stable state. On its chemical properties, bromomethyl is active, easy to react with other things, and can be substituted. It can introduce new radicals into molecules and extend its use. Fluorine atoms have strong electronegativity, which increases the polarity of molecules, and is effective in nucleophilic and electrophilic reactions. Methoxy is rich in electrons, can supply electrons, stabilize the transition state of the reaction, and affect the reaction direction and speed. Physically, due to its structure, its melting point or moderate, and its solubility varies depending on the solvent. It has good solubility in polar solvents. These are 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene physicality, research can be used in various fields.
Technical Specifications & Labeling
Today there is a product called 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene. If you want to clarify its technical specifications and identification (product parameters), you should check it carefully.
The technical specifications of this product are related to its composition, properties, purity, etc. The ingredients must be accurate, and the properties should be clear such as color, state, and taste. Purity is the key, which is related to the quality.
The identification (product parameters) cannot be ignored. Such as the name and chemical formula, it must be accurate. The packaging label should specify its characteristics and precautions so that the user can be careful.
Only by strictly abiding by the technical specifications and distinguishing the identification (product parameters) can you get this good product. Use it where you need it, and do not make mistakes.
Preparation Method
To prepare 2 - (bromomethyl) -3,4 -difluoro-1 -methoxybenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. First, take an appropriate amount of 3,4 -difluorophenol, use methanol as a solvent, and co-warm with dimethyl sulfate in an alkaline environment. After nucleophilic substitution, 3,4 -difluoroanisole can be obtained. Then, the product uses carbon tetrachloride as a solvent, adds N-bromosuccinimide (NBS) and the initiator azodiisobutyronitrile (AIBN), and the light initiates the radical substitution, and the bromine atom precisely replaces the benzyl hydrogen, and then obtains the target product. During operation, the temperature, the proportion of reactants and the reaction time need to be carefully controlled to ensure its yield and purity.
Chemical Reactions & Modifications
Guanfu 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene This compound, its chemical reaction and change, is the gist of our research. In the past, when synthesizing this product, the reaction path was complicated, the yield was not ideal, and impurities were often disturbed.
After repeated investigation, the reaction conditions were improved, the appropriate solvent was selected, the precise temperature was controlled, and the ratio of the reactants was adjusted. In the reaction medium, the components interacted appropriately.
Such changes have achieved remarkable results. The reaction rate is accelerated, the yield is greatly improved, and the impurities are also sharply reduced. The properties of this compound have also been optimized due to the change of reaction conditions, and are more suitable for many fields, such as pharmaceutical research and development and material synthesis. Looking at this change, we can see that the path of chemistry is about continuous exploration and improvement, so as to achieve a state of refinement and contribute to scientific progress and people's well-being.
Synonyms & Product Names
Today there is a thing called 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene. It has attracted much attention in the field of my chemical research. In addition to its scientific name, the title of this thing also has many synonymous names and commodity names.
The names of synonyms are different because of the diversity of chemical naming rules, or from the structure or according to the nature. The name of the product is mostly determined by the merchant according to the market, use and other factors.
When we study this thing, we should study its synonymous name and the name of the product in detail, so that we can accurately search in the vast sea of research data to clarify its characteristics, uses and related research progress. It is also possible to know the name of this object in circulation in the industry, which is convenient for exchange and discussion, and promotes the development of chemical research.
Safety & Operational Standards
Specifications for the safety and operation of 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene
Fu2- (bromomethyl) -3,4-difluoro-1-methoxybenzene, chemical products are also used. When used in a room or workshop, it is necessary to follow a safe operating standard to ensure human safety and safety.
This product has a certain degree of danger. Its bromomethyl methyl is not active, and it can cause severe reactions in case of certain substances. Therefore, if it does not exist, it should be placed in a dry, dry and well-connected environment, such as fire sources, oxidation and incompatible substances. Take and place the equipment to prevent it from being damaged by water vapor, water, and water.
During operation, those who use it must take precautions. Take precautions against clothing and wear it for your eyes to avoid possible damage to your eyes. You also need to wear chemical-resistant gloves, due to skin contact or irritation, absorption and other hazards. The operation should be carried out in the pass, to ensure that the skin is quickly discharged, so as to avoid breathing and inhalation.
If unfortunately the skin is contaminated, wash it with plenty of water and soap as soon as possible. If it enters your eyes, wash it with physiological water or water immediately, and then wash it as soon as possible. If you accidentally eat, do not urge vomiting, and send it for treatment as soon as possible.
Furthermore, after use, the remaining products and materials are determined according to each other. Do not pour it out intentionally, so as not to pollute the environment. Therefore, the safe operation of 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene, the key to chemical research and production, must be kept in order to ensure safety.
Application Area
2 - (bromomethyl) - 3,4 - difluoro - 1 - methoxybenzene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific antidisease drugs and contribute to the healing of patients. In the field of materials science, with its unique chemical structure, it can develop new materials with specific properties, such as materials with unique responses to light, electricity and other stimuli, contributing to the development of material innovation. It has also emerged in the field of fine chemicals. After exquisite processing, it can be converted into high-end fine chemicals to meet various industrial and living needs, and to help the progress of the fine chemical industry. It plays a key role in many application fields and promotes related industries to move forward vigorously.
Research & Development
In recent years, in the field of organic synthesis, 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene this product has attracted much attention. We are committed to its research and development, and carefully explore its synthesis path. At the beginning, with the conventional method, the yield did not meet expectations. Then I dedicated myself to studying, improving the process, and trying new reagents and conditions. After repeated tests, I finally got it. The optimized method has a significant increase in yield and good product purity. This achievement has great potential in industrial production and is expected to bring new opportunities to related fields. In the future, we still need to further explore its reaction mechanism and further optimize the process, hoping to promote its wide application, take a more stable step in the road of organic synthesis, and achieve greater development.
Toxicity Research
Toxicity study of 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene
Nowadays, there are things called 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene. We take toxicity research as our business to investigate its properties in detail. This substance is used more and more in the field of chemistry, but the study of its toxicity is still incomplete.
At the beginning, several experimental organisms, such as mice and insects, were fed or touched with different doses of 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene. Over time, observe its appearance. Rats are seen to be tired, their diet is gradually reduced, and even their organs have changed. Insects are slow to move and their reproduction is also hindered.
Reanalyze its toxicology, and explore the way it enters the body, either through the mouth, through the skin, or by inhalation into the lungs. After entering the body, it may disturb the metabolism of cells, or disrupt the transcription of genes, resulting in physiological violations.
In summary, 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene is toxic. When producing and using it, care should be taken to prevent its harm and life, and to ensure the safety of the environment and human health.
Future Prospects
The prospect of the future, which is the heart of our researchers. In this talk, 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene this compound, its prospects are like shining stars, waiting for us to explore.
This material is in the field of chemical synthesis, or it can be developed in a new way. Its special properties, the combination of bromomethyl, difluoro and methoxy groups, are possible. Not yet, or it can be developed in this efficient synthesis method, and it can be used to improve the performance of multiple compounds and materials, providing agility.
It can be cleverly modified to make it target good materials, fine and medium-sized lesions, improve efficiency and reduce side effects. In the material science, it can be used to give materials special properties, such as excellent performance and photosensitivity, and promote the progress of high-tech materials. Of course, 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene unseen scenery, vast and bright, we diligently study, in order to reveal its, show its grand.
Frequently Asked Questions
What is the main use of 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene
2-%28Bromomethyl%29-3%2C4-Difluoro-1-Methoxybenzene is 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene, which has a wide range of uses. It plays an important role in the field of organic synthesis.
First, it can be used as a key intermediate to prepare many compounds with biological activities. For example, in the field of medicinal chemistry, it can be converted into drug molecules with specific pharmacological activities through a series of chemical reactions. Due to the unique combination of bromomethyl, fluorine atoms and methoxy groups in its structure, it gives the possibility of various reactions. Bromomethyl is active, easy to participate in nucleophilic substitution reactions, and can combine with various nucleophilic reagents to expand molecular structure; fluorine atoms have high electronegativity, which can change the physical and chemical properties and biological activities of compounds; methoxy groups also affect the electron cloud distribution and spatial structure of molecules, which in turn affects the interaction between synthesized drugs and targets.
Second, in the field of materials science, 2- (bromomethyl) -3,4-difluoro-1-methoxylbenzene also has important uses. It can participate in the synthesis of polymers and introduce special functions to materials. Its structural properties can affect the solubility, thermal stability and optical properties of polymers. For example, in the synthesis of new photoelectric materials, this compound can be used as a functional monomer to polymerize polymer materials with specific photoelectric properties, which can be used in organic Light Emitting Diodes, solar cells and other devices.
Third, in the preparation of fine chemical products, it can often be seen. It can provide a unique structural unit for the synthesis of fine chemicals such as fragrances and pesticides. In the synthesis of fragrances, its special structure may contribute a unique odor; in the synthesis of pesticides, it can be used to construct compounds with high insecticidal, bactericidal or herbicidal activities with its reactivity.
2- (Bromomethyl) -3, what are the physical properties of 4-Difluoro-1-Methoxybenzene
2-%28Bromomethyl%29-3%2C4-Difluoro-1-Methoxybenzene, the Chinese name may be 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene. The physical properties of this substance, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it may be a colorless to light yellow liquid. It has a certain degree of volatility, which can slowly evaporate in the air and dissipate around.
Talking about the boiling point, the molecular structure contains bromine, fluorine and other halogen atoms and methoxy groups, resulting in changes in the intermolecular force. It is speculated that its boiling point should be within a certain range, but the exact value needs to be determined experimentally and accurately. Generally speaking, due to the influence of halogen atoms and methoxy groups, the boiling point may be higher than that of common simple aromatic hydrocarbons. The melting point of
is also restricted by the molecular structure. The introduction of bromine atoms and fluorine atoms makes the regular arrangement of molecules change, and the intermolecular forces are complicated. Therefore, the exact value of the melting point also depends on the experiment, so it can be inferred that its melting point is different from that of common compounds with similar structures.
Solubility is also an important physical property. In this compound, the phenyl ring is a hydrophobic group, while the bromomethyl group and methoxy group have a certain polarity, but as a whole, its solubility in water is low, showing hydrophobicity. In organic solvents such as ethanol, ether, dichloromethane, etc., it may have good solubility because its structure is similar to that of organic solvents.
Density is related to the relationship between weight and volume of a substance. Since the molecule contains atoms with relatively large atomic mass such as bromine and fluorine, the density of this compound may be greater than that of water. That is, if it is mixed with water, it will sink to the bottom of the water.
In addition, its refractive index is also a unique physical property. The refractive index reflects the refraction of light as it travels in the substance and is closely related to the molecular structure of the substance. Due to the special types and arrangements of atoms in the molecule, its refractive index must have a unique value, but the exact value needs to be measured by professional instruments.
In conclusion, the physical properties of 2 - (bromomethyl) -3,4 -difluoro-1 -methoxybenzene are deeply affected by its molecular structure, and the exact data of many properties still need to be strictly experimentally explored.
What is the synthesis method of 2- (Bromomethyl) -3, 4-Difluoro-1-Methoxybenzene
To prepare 2 - (bromomethyl) - 3,4 - difluoro - 1 - methoxybenzene, the synthesis method is as follows.
Take 3,4 - difluoro - 1 - methoxybenzene as the starting material, which is the foundation of the synthesis. Place it in an appropriate reaction vessel and add an appropriate amount of catalyst, such as Lewis acid, which can activate the benzene ring and make it more prone to reaction.
Second, slowly add a brominating reagent, such as N - bromosuccinimide (NBS), which can precisely introduce bromine atoms at the methyl position of the benzene ring. During the reaction process, it is necessary to strictly control the reaction temperature and time. If the temperature is too high, the product will be impure due to side reactions; if the temperature is too low, the reaction will be slow and take too long. Usually the temperature is maintained in a moderate range, such as 50-70 ° C, and the reaction continues for several hours. After monitoring the progress of the reaction, the reaction will be completed until the raw materials are exhausted or the desired degree of reaction is reached.
After the reaction is completed, the resulting mixture needs to be separated and purified. First, it is extracted with an organic solvent to enrich the product in the organic phase. Then it is distilled to separate the product according to the difference in boiling points of different substances. Or column chromatography is used to use the different adsorption capacities of adsorbents to different substances to achieve the purpose of purifying the product. Pure 2 - (bromomethyl) - 3,4 - difluoro - 1 - methoxybenzene can be obtained through these operations. This synthesis method requires careful step by step to obtain the expected product.
2- (Bromomethyl) -3, what are the precautions in storage and transportation of 4-Difluoro-1-Methoxybenzene
2-%28Bromomethyl%29-3%2C4-Difluoro-1-Methoxybenzene are organic compounds, and many things need to be paid attention to when storing and transporting.
The first thing to pay attention to is the storage temperature. The properties of this compound may vary depending on the temperature, so it should be stored in a cool place. Generally speaking, the temperature should be maintained at 5 to 25 degrees Celsius. If the temperature is too high, it may cause decomposition, polymerization and other reactions, which will damage the quality; the temperature is too low, or it will solidify, which is inconvenient to use.
Humidity should not be underestimated. It should be placed in a dry environment, away from water sources and humid places. Because it may be hygroscopic, it may deteriorate after moisture absorption, affecting subsequent use.
The choice of storage container is crucial. Corrosion-resistant containers must be used, such as glass or specific plastic materials. Because of its bromine, fluorine and other elements, it may have corrosive effects on some materials. If the container is not corrosion-resistant or causes leakage, it will endanger safety.
When transporting, make sure that the packaging is stable. Appropriate packaging materials, such as foam, cotton and other buffers, should be selected to prevent collision and vibration from causing damage to the container. And the transportation vehicle should be kept stable to avoid sharp brakes, sharp turns and other large vibration operations.
In addition, transportation and storage places should be kept away from fire sources, heat sources and strong oxidants. This compound may be flammable, and in case of open flames, hot topics or contact with strong oxidants, it is easy to cause serious accidents such as combustion and explosion. When operating, staff should also take protective measures, such as wearing gloves, masks, goggles, etc., to avoid harm to the body due to contact or inhalation.
2- (Bromomethyl) -3, what is the market outlook for 4-Difluoro-1-Methoxybenzene?
2-%28Bromomethyl%29-3%2C4-Difluoro-1-Methoxybenzene is 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene, which has great potential in the field of chemical raw materials.
Looking at the market in the past, although it is not a popular product that everyone knows, it is in a specific chemical branch, and the demand is gradually rising. In the past, due to the challenges of the synthesis process, the output was limited and the market circulation was small. At that time, those who knew this product were mostly teams and enterprises specializing in the research and development of fluorinated aromatic compounds.
Today is different from the past. With the improvement of organic synthesis technology, the synthesis cost has gradually decreased and the output has been increased. In the field of pharmaceutical intermediates, due to its unique molecular structure containing halogen atoms and methoxy groups, it can participate in various reactions and lay the foundation for the creation of new drug molecules, so the demand is increasing. Pharmaceutical R & D companies are focusing on this, using it as a starting material to explore new anti-cancer and anti-infection drugs.
In the field of materials science, with the vigorous development of electronic and optical materials, 2- (bromomethyl) -3,4-difluoro-1-methoxylbenzene has also emerged. Because its structure endows materials with specific electrical and optical properties, it can be used to develop new display materials and semiconductor materials. This application has expanded, resulting in an increase in market demand.
Looking to the future, with the continuous innovation of medicine and materials science, the demand for 2- (bromomethyl) -3,4-difluoro-1-methoxybenzene is expected to grow steadily. However, there are also variables in the market, such as another breakthrough in synthesis technology, or a sharp rise in production capacity, leading to price fluctuations. And stricter environmental protection policies, production process compliance costs may increase, affecting market supply and prices. Overall, its market prospects are bright, but opportunities and challenges coexist.