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2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene

2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    176889

    Chemical Formula C8H5BrClF3
    Molar Mass 287.48 g/mol
    Appearance Liquid (usually)
    Boiling Point Data may vary, typically in a certain range based on purity
    Melting Point Data may vary depending on purity and other factors
    Density Specific value depending on conditions
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in many organic solvents like dichloromethane, toluene etc.
    Vapor Pressure Varies with temperature
    Flash Point Data may be required for safety handling

    As an accredited 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle packaging for 2-(bromomethyl)-1 - chloro - 4-(trifluoromethyl)benzene.
    Storage 2-(Bromomethyl)-1-chloro-4-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential reactions.
    Shipping 2-(Bromomethyl)-1-chloro-4-(trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. It's carefully packaged in suitable containers to prevent leakage, ensuring safe transit.
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    2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    In the past, there were chemical things, named 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene. At the beginning, it only existed in the thoughts of the wise, not in the world.
    At that time, the study of various scholars was unremitting, exhaustive, and gradual. After years of hard work, explore the nature of matter, and seek ways to change. Or between the bottles and kettles, adjust the medicines and observe their response; or on the books, think about the mechanism and push them to change.
    Years go by, all kinds of attempts, or fail or succeed. Those who are determined to persevere will eventually find the way. Only then can we make this chemical product and make it appear in the world. Since then, this material has gradually been used in various fields to develop its capabilities, and the evolution of its history has also inspired future generations to pursue the truth of science.
    Product Overview
    Today there is a substance called 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene. Its shape is also an organic compound with the characteristics of halogenated aromatics. In this substance, bromomethyl, chlorine atoms and trifluoromethyl coexist on a benzene ring.
    Looking at its properties, it has unique physical and chemical properties due to halogen atoms and fluorine-containing groups. Its physical properties, or colorless to light yellow liquids, are volatile and soluble in specific organic solvents.
    In terms of chemical properties, bromomethyl has good activity and can participate in many nucleophilic substitution reactions. Although chlorine atoms are less active than bromomethyl, they can also participate in the reaction under suitable conditions. The introduction of trifluoromethyl makes the compound have special electronic effects and hydrophobicity, which affects its reactivity and molecular interactions. In the field of organic synthesis, this compound may be an important intermediate, which can be prepared through various reaction pathways for various organic materials, medicines or pesticides with special functions.
    Physical & Chemical Properties
    The physicochemical properties of this compound are of paramount importance. Its external properties are often specific, either in the form of a liquid or in the form of a solid, depending on the degree and force of the environment. The melting and boiling conditions are all determined. The melting conditions are determined by the degree of solidification of the liquid, and the boiling conditions of the liquid.
    In addition, the solubility is also important. In different dissolution conditions, the degree of solubility varies. It is soluble in solutions such as ethanol and ether, or soluble in water or the like. Its chemical properties, activity, and atomic properties, can be used for multiple reactions, such as nuclear substitution, and can generate new compounds with different effects.
    Technical Specifications & Labeling
    Today, there is a product named 2 - (bromomethyl) -1 - chloro - 4 - (trifluoromethyl) benzene, which is of great importance to our chemical research. Its technical specifications and identification (commodity parameters) must be carefully studied.
    Looking at its technical specifications, when the preparation method is strictly adhered to, from the selection of raw materials to the reaction conditions, such as temperature, duration, and quantity ratio, all must be accurate. The purity of the reaction environment and the sophistication of the equipment should not be ignored. In this way, a product with a pure texture can be obtained.
    When it comes to its identification (commodity parameters), the color, taste, and state should be known first, and its purity and content should be re-tested to determine the quality. It is also necessary to record the appropriate storage and access regulations in detail to ensure the stability of this material. Only by following the technical specifications and labels can we make good use of this material in the research and make good use of it for the chemical industry.
    Preparation Method
    To prepare 2- (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene, first take an appropriate amount of chlorotrifluoromethylbenzene as substrate, use carbon tetrachloride as solvent, add an appropriate amount of N-bromosuccinimide (NBS) as bromine source, azobisisobutyronitrile (AIBN) as initiator. Heat to a suitable temperature, about 70-80 degrees Celsius, and continue to stir the reaction. This is the mechanism of free radical substitution reaction. During the reaction, the reaction process can be closely monitored and can be tracked by thin layer chromatography (TLC). After the reaction is complete, the reaction system is cooled, the solvent is removed by reduced pressure distillation, and then the pure 2 - (bromomethyl) -1 - chloro-4 - (trifluoromethyl) benzene product is separated and purified by column chromatography. In this way, the raw materials, preparation process, reaction steps and conversion mechanism are all available, which can lead to the preparation of this compound.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, it is related to the change of substances. Today there is 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene, and its chemical reaction and modification can be quite studied.
    Looking at its reaction, when it encounters various reagents, it often becomes different. Or nucleophilic substitution, or addition polymerization, varies according to conditions. If temperature and humidity, the nature of catalysts, can affect its change.
    As for modification, in order to improve its characteristics. Or increase its stability, or change its solubility, to suit all needs. By chemical methods, adjust the structure of its molecules and change its properties.
    When we are in chemistry, we should study the mechanism, understand the rules of the reaction, and understand the method of modification. We hope to make good use of this science to contribute to the progress of the chemical industry, so that this substance can be used wonderfully and benefit the world.
    Synonyms & Product Names
    2 - (bromomethyl) - 1 - chloro - 4 - (trifluoromethyl) benzene, this substance is very important in chemical research. Its synonyms and trade names, like all other names in ancient books, have their own origins.
    In the past, chemists first obtained this substance. Looking at its structure, it was named 2- (bromomethyl) - 1 - chloro - 4 - (trifluoromethyl) benzene according to the chemical nomenclature. In different places, different research groups, due to different habits or focuses, also have many synonyms.
    As for trade names, merchants have different trade names in order to make their products different and easy to remember in the market, or according to their characteristics, uses, or auspicious names. This is a natural phenomenon in the process of chemical research and commercial promotion. Like rivers converging, all names flow in parallel, referring to this substance together, and it has its unique significance in the development of chemistry.
    Safety & Operational Standards
    2 - (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene safety and operating specifications
    Fu 2 - (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene is an important substance in chemical research. During its experimental operation and use, safety is essential, and strict regulations must be followed.
    This substance has certain chemical activity. In case of open flame, hot topic or oxidant, it may burn or explode. Therefore, it must be stored in a cool and ventilated warehouse, away from fire and heat sources, and the warehouse temperature should not exceed 30 ° C. At the same time, it should be stored separately from oxidants and edible chemicals, and should not be mixed.
    When operating, the experimenter must wear professional protective equipment. Wear protective clothing to prevent skin contact; wear protective gloves to avoid hand invasion; wear safety glasses to protect your eyes from harm. Good ventilation facilities are also required in the operation room to reduce the concentration of this substance in the air.
    If you accidentally come into contact with the skin, you should immediately remove the contaminated clothing, rinse with plenty of flowing water for at least 15 minutes, and then seek medical attention. If splashing into the eyes, immediately lift the eyelids, rinse thoroughly with plenty of flowing water or normal saline for at least 15 minutes, and seek medical attention promptly.
    When taking this substance, be sure to operate it accurately, and take it according to the amount required by the experiment. Beware of waste and leakage. In the event of a leak, personnel from the leaked contaminated area should be quickly evacuated to a safe area and isolated, and access should be strictly restricted. Emergency personnel wear self-contained positive pressure respirators and anti-toxic clothing. Do not directly contact the leaks. Small leaks, mix with sand, dry lime or soda ash, and collect in a dry, clean, covered container. If there are a large number of leaks, build a dike or dig a pit for containment, cover it with foam to reduce steam disasters, and transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
    In short, in the research and use of 2 - (bromomethyl) - 1 - chloro - 4 - (trifluoromethyl) benzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment and the well-being of personnel.
    Application Area
    Today there is a product called 2- (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene. This chemical product has its uses in various fields.
    In the field of medicine, it can be used as a key intermediate. Through fine synthesis, it can help to form a special medicine to treat various diseases and save patients from pain.
    In the world of materials, it can add strength to modification. Through special processes, new materials are integrated to increase their properties, such as corrosion resistance and wear resistance, and extend the application breadth of materials.
    In the path of scientific research, it is the cornerstone of exploring the unknown. Scientists use its unique structure to carry out various experiments, explore the mysteries of chemistry, seek new methods, and promote the study of chemistry to move forward vigorously. It is widely used, and it is an indispensable thing in the chemical world.
    Research & Development
    Today, there is a product called 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene, which is particularly important in the field of my chemical research. We have dedicated ourselves to studying, striving to clarify its properties, explore its production method, and hope to have innovation and development.
    At the beginning of the research, we have carefully observed its structure and known its characteristics. This is the basis for exploration. Then we studied the synthesis method. After many attempts, we either changed the reaction conditions or changed the raw materials and reagents, and found a better path. Although the process is difficult, we know that this research is of great significance.
    Looking to the future, if we can make breakthroughs in the synthesis method, we may optimize its performance and expand the field of application. Whether it is in the field of materials science or medicine, it is expected to advance accordingly. We should persevere and do our best for the development of chemistry, the research and expansion of this substance, and hope to achieve something, so as to feed the academic community and benefit the world.
    Toxicity Research
    Since modern times, chemical refinement has resulted in the emergence of various new substances. Today, 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene is a chemical. In the field of my chemical research, the investigation of its toxicity is of paramount importance.
    We have used scientific methods to investigate this chemical in detail. Observe the structure of its molecules, analyze the nature of its reactions, and explain the various effects it produces in biological systems. After various experiments, it can be known that this substance may have an impact on cell metabolism and gene expression.
    Although the current research is not complete, it has already begun to emerge. Its toxicity involves the balance of ecology and the survival of organisms. We should do our best to study it in depth, so that we can seek advantages and avoid disadvantages, so that this chemical can be used in a suitable place and will not cause harm to the world.
    Future Prospects
    Today there is a thing named 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene. We are chemical researchers, looking at this thing and thinking about its future development. This material is unique, or it has extraordinary uses in the fields of medicine and materials.
    Looking forward to the future, in the field of medicine, it may be able to use its characteristics to make special drugs and treat intractable diseases. In the field of materials, we can develop new materials with excellent properties, such as stronger and more corrosion resistance, based on its characteristics.
    Although the road ahead is uncertain, we chemical researchers should explore with the heart of exploration and study unremitting. With wisdom and hard work, we hope to make this material shine in the future, creating a new situation for the well-being of mankind and expanding its infinite possibilities.
    Where to Buy 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene in China?
    As a trusted 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Bromomethyl)-1-Chloro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene?
    2-%28Bromomethyl%29-1-Chloro-4-%28Trifluoromethyl%29Benzene is 2- (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene, which has a wide range of uses.
    In the field of organic synthesis, it can be used as a key intermediate. Because its structure contains active groups such as bromomethyl, chlorine atoms and trifluoromethyl, it can build complex organic molecular structures through various chemical reactions, such as nucleophilic substitution and coupling reactions. For example, in pharmaceutical chemistry, it can be used to synthesize compounds with specific biological activities. Through nucleophilic substitution, bromomethyl can react with nucleophilic reagents containing nitrogen, oxygen, sulfur, etc., and introduce various functional groups, laying the foundation for the creation of novel drug molecules.
    In the field of materials science, 2- (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene is also useful. Because of its trifluoromethyl content, it can endow the material with unique properties, such as excellent weather resistance, chemical stability and low surface energy. It can be used as a monomer to polymerize and prepare special functional polymer materials for use in coatings, plastics and other fields to improve the properties of materials.
    In the research and development of pesticides, this compound can become a lead compound for structural modification and optimization. With its halogen atom and trifluoromethyl properties, it may endow pesticides with better biological activity and environmental compatibility, thus creating new pesticide products with high efficiency and low toxicity.
    What are the physical properties of 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene?
    2 - (bromomethyl) -1 -chloro-4- (trifluoromethyl) benzene is one of the organic compounds. Its physical properties are particularly important and are related to the many uses and reaction characteristics of this compound.
    First of all, its appearance is often colorless to light yellow liquid, with a clear texture and a special odor. The characteristics of this odor may be related to the functional groups such as bromine, chlorine and trifluoromethyl in the molecule. Looking at its color, colorless to light yellow state is one of the characteristics to distinguish this substance.
    The times and boiling points are due to the existence of different electronegativity atoms in the molecule, resulting in complex intermolecular forces. Therefore, its boiling point may be within a specific range, between [X] ° C and [X] ° C. The value of the boiling point is determined by the molecular structure. The presence of bromine, chlorine and trifluoromethyl makes the attractive forces between molecules different, which in turn affects the energy required for gasification.
    Furthermore, the melting point of this substance also varies according to the molecular structure characteristics, and is about [X] ° C. The level of melting point is related to the close arrangement of molecules and the strength of the interaction force. In this compound, the spatial arrangement of atoms and functional groups affects the interaction between molecules, resulting in a specific melting point.
    In terms of solubility, due to its organic structure, it has good solubility in organic solvents such as dichloromethane, chloroform, and ether. Due to the principle of "similarity and miscibility", the structure of the organic molecule has a similar force to that of the organic solvent molecule, which is conducive to mixing with each other. In water, due to its hydrophobicity, the solubility is very small.
    In terms of density, because the molecule contains bromine, chlorine, fluorine and other elements with relatively large atomic mass, its density may be greater than that of water, which is about [X] g/cm ³. This density characteristic is of great significance in the separation, purification and judgment of the phase behavior of related chemical reactions. In conclusion, the physical properties of 2 - (bromomethyl) -1 - chloro - 4 - (trifluoromethyl) benzene, such as appearance, boiling point, melting point, solubility, and density, are determined by their unique molecular structures, and each plays an important role in chemical research and practical applications.
    What is the synthesis method of 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene
    2-%28Bromomethyl%29-1-Chloro-4-%28Trifluoromethyl%29Benzene is 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene, and its synthesis method is as follows:
    First, start from 4- (trifluoromethyl) benzaldehyde. In the common method, 4- (trifluoromethyl) benzaldehyde is reacted with a brominating agent, such as hydrogen bromide or N-bromosuccinimide (NBS), under appropriate reaction conditions. If NBS is used, benzoyl peroxide (BPO) is often used as the initiator, and it is heated and refluxed in an inert solvent such as carbon tetrachloride. This step of the reaction takes advantage of the characteristics of NBS, which can selectively replace the hydrogen atom of the aldehyde alpha-position with a bromine atom to obtain 2-bromomethyl-4- (trifluoromethyl) benzaldehyde.
    Then, the resulting 2-bromomethyl-4- (trifluoromethyl) benzaldehyde is chlorinated. Select a suitable chlorinating agent, such as chlorine gas or sulfonyl chloride (SO 2O Cl ²), and react in the presence of light or catalyst. If chlorine is used as a chlorinating agent, under light conditions, the hydrogen atom in the ortho-position of the aldehyde group can be replaced by a chlorine atom to obtain the target product 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene.
    Another possible method can be started from 1-chloro-4- (trifluoromethyl) benzene. The Fu-gram alkylation reaction is carried out with a halogenated benzylation reagent, such as benzyl bromide, under the action of a Lewis acid catalyst, such as anhydrous aluminum trichloride. This reaction can introduce bromomethyl to a specific position in the benzene ring, thereby synthesizing 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) During the
    synthesis process, it is necessary to pay attention to the precise control of reaction conditions, such as temperature, reaction time, reactant ratio, etc. After each step of reaction, it is often necessary to separate and purify to obtain high-purity target products.
    What are the precautions for 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene during storage and transportation?
    2-%28Bromomethyl%29-1-Chloro-4-%28Trifluoromethyl%29Benzene, that is, 2 - (bromomethyl) -1 - chloro - 4 - (trifluoromethyl) benzene. When storing and transporting this substance, you should generally pay attention to the following things.
    First, it is related to storage. Because of its chemical activity, it is easy to react with other substances, so it must be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent the chemical properties from changing due to the increase in temperature, or even cause dangerous reactions. And it must be placed separately from oxidizing agents, strong bases and other substances to cover it or react violently with these substances. It is appropriate to use anti-corrosion materials for storage to avoid material leakage caused by corrosion of the container.
    Second, as for transportation. When transporting, materials should be properly packaged, and commonly used packaging materials should have good sealing and corrosion resistance to ensure that there is no risk of leakage during transportation. During the handling process, the operator must handle it with care, and must not drop it or put heavy pressure on it to avoid damage to the packaging. The transportation vehicle should also be equipped with corresponding emergency treatment equipment and protective equipment in case of leakage and other accidents, so that it can be responded to in time. And the transportation route planning should also be careful to avoid densely populated areas and environmentally sensitive places, so as to reduce the harm to the public and the environment in the event of accidents.
    What are the effects of 2- (Bromomethyl) -1-Chloro-4- (Trifluoromethyl) Benzene on the environment and human health?
    2-%28Bromomethyl%29-1-Chloro-4-%28Trifluoromethyl%29Benzene is 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene. The impact of this substance on the environment and human health cannot be ignored.
    In the environment, due to the characteristics of halogenated aromatics, the chemical properties are relatively stable, not easy to degrade naturally, or cause long-term residual accumulation. If released in soil, it may affect soil quality, cause changes in soil microbial community structure and function, hinder normal plant growth and development, and affect crop yield and quality. If it flows into water bodies, it will pollute water sources, cause toxicity to aquatic organisms, interfere with the balance of aquatic ecosystems, and reduce biodiversity.
    As for human health, 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene may be potentially toxic. It can enter the human body through respiratory inhalation, skin contact or accidental ingestion. It may irritate the respiratory tract and skin, causing respiratory inflammation, skin allergies and other symptoms. Long-term exposure may damage the human nervous system, immune system, etc. When the nervous system is involved, it may cause dizziness, headache, fatigue, memory loss, etc.; Impaired immune system makes people vulnerable to pathogens and increases the risk of disease. Furthermore, such halogenated aromatics may be carcinogenic, and long-term exposure to them may increase the risk of cancer. Therefore, when manufacturing and using products containing 2- (bromomethyl) -1-chloro-4- (trifluoromethyl) benzene, proper protective measures must be taken to reduce its harm to the environment and human health.