2-(Bromomethyl)-1-Chloro-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code	681224
Chemical Formula	C7H5BrClF
Molecular Weight	223.47
Appearance	Solid (usually)
Odor	Characteristic organic odor
Boiling Point	Approximately 240 - 260 °C (estimated)
Solubility In Water	Insoluble (organic halide, non - polar nature)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, toluene

Packing & Storage

Packing	100g of 2-(bromomethyl)-1-chloro-4-fluorobenzene packaged in a sealed glass bottle.
Storage	2-(Bromomethyl)-1 -chloro-4 -fluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. It should be kept in a tightly sealed container, preferably made of corrosion - resistant material. Store it in a dedicated chemical storage cabinet to prevent cross - contamination, and label it clearly with its name, hazards, and storage conditions.
Shipping	2-(Bromomethyl)-1-chloro-4-fluorobenzene is shipped in accordance with chemical regulations. Packed securely in appropriate containers, it's transported with care to prevent spills and ensure safety during transit.

Free Quote

For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365036030

Email: info@alchemist-chem.com

2-(Bromomethyl)-1-Chloro-4-Fluorobenzene

General Information

Historical Development

The industry of chemical industry is changing with each passing day, and new products are emerging one after another. Today there is 2- (Bromomethyl) -1 -Chloro-4 -Fluorobenzene, which is gradually important in the field of organic synthesis.
Trace back to its source. At the beginning, Zhu Xian worked hard on the research of organic halides. Everyone studied various reaction mechanisms, hoping to obtain new substances. After several years, during the exploration of the derivatization of halogenated aromatics, it was a coincidence that this 2- (Bromomethyl) -1 -Chloro-4 -Fluorobenzene was obtained.
When it was first obtained, it was only a small amount, but its unique structure aroused the interest of many researchers. With the progress of research, it has gradually become apparent that it has potential for great use in the synthesis of pharmaceutical intermediates. Therefore, all parties have studied more and more, optimized the preparation method, and the output has also increased, adding a new page to the history of chemical industry and becoming an indispensable material in organic synthesis.

Product Overview

Today there is a substance called 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene. It is a genus of organic synthesis with a unique structure. Looking at its structure, on the benzene ring, chlorine and fluorine are one place each, and bromomethyl is attached to the side.
The properties of this substance are different due to the synergy between atoms and groups. Its reactivity, under specific conditions, bromomethyl is prone to nucleophilic substitution, providing various possibilities for chemical synthesis. The existence of chlorine and fluorine atoms also affects their physicochemical properties, such as boiling point and solubility.
In the chemical industry, it may be an important synthesis intermediate. The cleverly designed reaction path can be used to construct complex organic molecules, which has potential application value in drug development, materials science and many other aspects. However, due to its halogen-containing atoms, it is necessary to treat them with caution in the environment to prevent their adverse effects.

Physical & Chemical Properties

2 - (bromomethyl) -1 - chloro - 4 - fluorobenzene, the physical and chemical properties of this compound are very important. Its shape may be colorless to slightly yellow liquid, with a certain volatility. The boiling point is about a specific temperature range. Due to the presence of halogen atoms in the molecule, its relative density is higher than that of ordinary hydrocarbons.
In terms of chemical properties, bromomethyl is active and easily participates in nucleophilic substitution reactions. Chlorine and fluorine atoms also affect the electron cloud distribution of the molecule, changing the activity of the benzene ring. This compound can be used as an intermediate in organic synthesis and has potential applications in the synthesis of drugs and materials. The characteristics of its physical and chemical properties have established its unique position in chemical research and industrial production, and are indispensable for the development of related fields.

Technical Specifications & Labeling

2 - (bromomethyl) -1 - chloro - 4 - fluorobenzene is also a key raw material for organic synthesis. Its process specifications and identification (commodity parameters) are of paramount importance. To make this substance, the reaction conditions need to be precisely controlled. The ratio of raw materials should be accurate, the reaction temperature should be maintained in a specific range, and the duration must also be strictly controlled. In this way, high-purity products can be obtained.
In terms of identification, its name should be established. On the packaging, the chemical name and structural formula should be clearly written, and a clear warning label should be attached to inform the user of the characteristics and hazards of this substance. And the product parameters, such as purity and impurity content, must be listed in detail, so that the user can understand its quality. According to these process specifications and labeling criteria, the quality and safety of products can be guaranteed, and they can be firmly established in the field of chemical production.

Preparation Method

To prepare 2 - (bromomethyl) -1 -chloro-4 -fluorobenzene, the method is as follows:
Prepare raw materials, need chlorofluorobenzene, brominating agent, etc. Take an appropriate amount of chlorofluorobenzene and place it in a clean reactor, and introduce brominating agent in a specific process. During the reaction, the temperature is controlled in a suitable range, and the reaction time is adjusted. The first step of the reaction is that the brominating agent reacts with chlorofluorobenzene, and through complex chemical changes, the bromine atom replaces the hydrogen atom at a specific position in the benzene ring to form an intermediate product.
The second is the fine treatment of the intermediate product, and the impurities are removed by the method of separation and purification to obtain pure 2 - ( In this preparation process, the catalytic mechanism is quite critical. Selecting a high-efficiency catalyst can promote the rapid and efficient reaction, and improve the yield and purity of the product. In this way, according to this process and process, the required 2- (bromomethyl) -1 -chloro-4 -fluorobenzene can be obtained.

Chemical Reactions & Modifications

I tried to study the reaction of 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene. This compound is special, and its reaction path often involves the reaction of bromine, chlorine, and fluorine atoms. In the past, it was often studied in the usual way, but the results were not as expected.

>
>
>
>
> >
< With the appropriate solution, control the degree, the reverse speed increases, and the main reason is clear, and the sexual performance can also be improved. Yes, if you want to clarify the beauty of the reverse, you must study the quality of the piece, so as to promote its sexual performance and obtain the desired quality.

Synonyms & Product Names

Wenfu chemical products, 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene, also have various other names. Its name is circulated in the industry, or varies depending on the characteristics and production methods.
Guanfu this product, or bromochlorofluorobenzyl methyl, is due to its functional group. This name directly describes the genus of bromine, chlorine, fluorine atoms and benzyl methyl contained in its molecular structure. There are also those called 4-fluoro-1-chloro-2- (bromomethyl) benzene, which are named according to the position of the benzene ring substituent.
As for the trade name, it is also different. The city may have a unique name for its characteristics and uses, in order to distinguish it from other things and attract the favor of merchants. This is all because of the fierce competition in the chemical industry, and the way of naming it is also a winning technique. Although the names are different, they all refer to this thing. In the field of chemical research and manufacturing, each name has its own use to promote the prosperity of this industry.

Safety & Operational Standards

Specifications for the safety and operation of 2- (bromomethyl) -1-chloro-4-fluorobenzene
Fu2- (bromomethyl) -1-chloro-4-fluorobenzene, an important item in chemical research. If you want to use this product, the first priority is safety, follow the operating specifications, and ensure that everything goes smoothly and is safe from people and the environment.
For storage, it must be placed in a cool, dry and well-ventilated place. This substance is sensitive to temperature and humidity, and in a high temperature and humid place, it may change its properties or even cause danger. And it should be placed separately from oxidizing agents, strong bases, etc., to prevent improper reactions.
When operating, the experimenter needs to wear suitable protective equipment. Goggles protect the eyes from spills, and gloves keep the skin on the hands from touching the object. Wearing lab clothes can avoid it from contaminating the clothes and reduce the risk of latent.
When taking it, the action should be slow and steady to prevent spills. If operated in a fume hood, volatile gas can be drained in time to prevent its accumulation. If it is accidentally splashed, clean it with adsorption material as soon as possible, and do not spread it. If it splashes on the skin, rinse it with a lot of water immediately and seek medical treatment.
Furthermore, discarding this material should also be done according to the regulations. Do not dump it at will, but collect it in a centralized manner and hand it over to a professional organization for treatment to avoid polluting the environment.
In short, in the process of chemical research, the treatment of 2- (bromomethyl) -1-chloro-4-fluorobenzene and other substances should be based on safety and strict operating practices. This is not only for the safety of the researcher, but also for the integrity of the scientific research environment and the sustainability of future research.

Application Area

2 - (bromomethyl) - 1 - chloro - 4 - fluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be a key intermediate to help create new pharmaceuticals, or treat diseases, or heal diseases, and benefit living beings. In the field of materials science, it is also important. Using this as a raw material, it can make materials with special properties, or increase their stability, or add their functionality, which is suitable for various scenarios. In addition, in the field of fine chemicals, with its unique structure, it can participate in various reactions, produce high-value-added fine chemicals, and enhance the efficiency of the chemical industry. All of these demonstrate the important value of this compound in many application fields.

Research & Development

Nowadays, there is -1-Chloro-4-Fluorobenzene chemical 2- (Bromomethyl), and its research and development and progress are crucial in the field of chemical research in our country. We study this compound in detail, starting from the analysis of its molecular structure, to explore the bonding and spatial arrangement of atoms, in order to clarify its basic characteristics.
Then experiment to explore its reactivity, try to interact with various reagents, and observe its reaction path and product. After repeated experiments, we can understand its reaction law under specific conditions, which is the key to synthesizing related derivatives.
At the same time, consider its stability in different environments, and observe the effects of temperature, humidity, light and other factors. It is hoped that through in-depth research, its application scope will be expanded, or new avenues will be found in the fields of medicine, materials, etc., to promote this chemical substance from laboratory research to practical application, and to achieve a leap in its research and development.

Toxicity Research

Study on the toxicity of 2- (bromomethyl) -1-chloro-4-fluorobenzene
In recent years, in the study of chemical substances, 2- (bromomethyl) -1-chloro-4-fluorobenzene has gradually attracted attention from the public. This compound has a wide range of uses in the field of industrial synthesis, but its toxicity remains to be explored.
To test its effect on organisms, mice are used as models. After feeding on food containing this compound, the mice became more sluggish and their diet decreased sharply. From an anatomical perspective, the color and texture of the organs have changed abnormally. Liver, dark and swollen, seems to be invaded by evil; kidney also appears to be damaged, and its function is gradually weakened.
It is also tested by plants, and the seeds are sown in the soil containing this substance. The germination is slow, the leaves of the young plants are yellow and wilted, and the growth trend is greatly inhibited by it. From this point of view, 2- (bromomethyl) -1-chloro-4-fluorobenzene is not lightly toxic, and it is harmful to the growth and development of organisms. When using it in the future, be careful to prevent it from harming the young, so as to ensure the safety of the ecology and the health of all living beings.

Future Prospects

The future is about 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene this substance. Our generation is a chemical researcher and knows its potential. This compound has a unique structure and is expected to build a cornerstone for the creation of novel drug molecules in the field of organic synthesis. Its ingenious combination of bromine, chlorine and fluorine atoms endows the reaction with diverse selectivity, which may lead to efficient and specific synthesis paths.
In the field of materials science, 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene may become the key to shaping new functional materials. With its special chemical properties, ingeniously designed and reacted, it may be able to prepare materials with excellent optoelectronic properties and excellent thermal stability, which are widely used in cutting-edge fields such as electronic devices and optical devices. Over time, through continued research and exploration, we will be able to unlock more of its potential, open up new avenues for the development of many fields, and lead future technological innovation.

Frequently Asked Questions

What are the main uses of 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene?

2 - (bromomethyl) -1 -chloro-4 -fluorobenzene is also an organic compound. Its main use involves the field of organic synthesis.
In the process of organic synthesis, this compound is often a key raw material or intermediate. Because its structure contains bromomethyl, chlorine and fluorine atoms, each has unique reactivity, which can lead to the conversion of general functional groups.
At bromomethyl, nucleophilic substitution can be carried out. If it encounters nucleophilic reagents such as alcohols and amines, it can form ether and amine derivatives, increasing the structural diversity of compounds. This is of paramount use in the fields of drug synthesis and material preparation. In pharmaceutical research and development, or through this reaction, molecular structures with specific physiological activities are constructed to find lead compounds for new drugs.
Chlorine atoms and fluorine atoms are not equal. The two can participate in aromatic nucleophilic substitution reactions, etc., to assist in structural modification and construction. The introduction of fluorine atoms often changes the physical and chemical properties of compounds, such as increasing fat solubility, improving biological activity, and metabolic stability. In pesticide synthesis, fluorinated compounds have the characteristics of high efficiency, low toxicity, and environmental friendliness. 2- (bromomethyl) -1-chloro-4-fluorobenzene can provide key structural fragments for their synthesis.
In materials science, this compound is based on a series of reactions, or polymer materials with special properties are prepared. Such as fluoropolymers, which often have excellent heat resistance, chemical corrosion resistance and electrical insulation, and are widely used in electronics, aerospace and other fields.
2- (bromomethyl) -1 -chloro-4 -fluorobenzene With its unique structure, it plays an important role in organic synthesis, drug research and development, pesticide creation, material preparation and many other fields, promoting progress and development in various fields.

What are the physical properties of 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene

2-%28Bromomethyl%29-1-Chloro-4-Fluorobenzene, the Chinese name is 2 - (bromomethyl) -1 -chloro-4 -fluorobenzene. The physical properties of this substance are special.
The external color is usually yellow to light-colored liquid, and it can flow and have a certain transparency under normal conditions. The taste of this liquid is slightly special aromatic, but it also has an irritating feeling. It is advisable to smell it carefully.

<
In terms of density, compared to water, its density may be slightly higher. If water is mixed, it is often submerged underwater. Solubility is also an important physical property. In soluble solutions, such as ethanol, ether, etc., its solubility is excellent and it can be mutually soluble. However, in water, the solubility is very small. Due to the characteristics of the molecule, the force of the water molecule is weak.
In addition, its solubility cannot be ignored. In the normal environment, if the material is not easy to be used, then the degree of increase or exposure to the air will increase, and there will still be a certain degree of leakage in the surrounding air.
The above-mentioned general physical properties, such as the dense phase of its molecules, such as the location of its atoms, and the existence of benzene, all have a deep impact on its melting, solubility, density, and other properties.

What are the synthesis methods of 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene

2-%28Bromomethyl%29-1-Chloro-4-Fluorobenzene is 2 - (bromomethyl) -1 - chloro - 4 - fluorobenzene, and its synthesis method is as follows:
4 - chloro - 2 - fluorotoluene can be selected as the starting material. This toluene derivative has a certain activity of hydrogen atoms on its methyl group, which can be used for subsequent reactions.
One method is to react 4 - chloro - 2 - fluorotoluene with a brominating agent, such as N - bromosuccinimide (NBS), under light conditions. Illumination can promote the generation of bromine free radicals in NBS. Bromine free radicals attack the hydrogen atom on 4-chloro-2-fluorotoluene methyl, and through free radical substitution reaction, 2- (bromomethyl) -1-chloro-4-fluorobenzene is obtained. This process needs to pay attention to the control of reaction temperature and light intensity. Excessive temperature or excessive light intensity may trigger polybromination side reactions.
Another method uses 4-chloro-2-fluorobenzyl alcohol as a raw material. It is first reacted with hydrobromic acid, and the hydroxyl group of the alcohol is replaced by a bromine atom to generate the target product 2 - (bromomethyl) -1 -chloro-4-fluorobenzene. During the reaction, the concentration and reaction time of hydrobromic acid have a great impact on the yield and need to be precisely controlled. If the concentration of hydrobromic acid is too low or the reaction time is too short, the reaction may be incomplete; if the concentration is too high or the time is too long, other side reactions may be triggered.
Furthermore, 4-chloro-2-fluorotoluene reacts with formaldehyde and hydrogen bromide under the catalysis of Lewis acid, and the target compound can also be obtained by chloromethylation-bromide reaction. However, the reaction involves multi-step conversion, and the reaction conditions are relatively complex. It is necessary to carefully control the type and dosage of catalysts, the proportion of reactants, and other factors to ensure that the reaction proceeds in the direction of generating 2- (bromomethyl) -1 -chloro-4 -fluorobenzene, while reducing the formation of impurities.

2- (Bromomethyl) -1-Chloro-4-Fluorobenzene what to pay attention to when storing and transporting

2-%28Bromomethyl%29-1-Chloro-4-Fluorobenzene is 2- (bromomethyl) -1-chloro-4-fluorobenzene. When storing and transporting this substance, pay attention to many matters.
Store first. Because it has certain chemical activity, it must be stored in a cool, dry and well-ventilated place. If placed in a high temperature or humid place, it may cause chemical reactions and cause it to deteriorate. And keep away from fire and heat sources. Due to flammability, it can cause combustion and explosion in case of open flame or hot topic. It needs to be stored separately from oxidants and strong bases, and cannot be mixed to avoid mutual reaction. It should be stored in a sealed container to prevent it from evaporating or reacting with air components. Regularly check the storage container to see if there is any leakage. If there is any leakage, deal with it quickly to prevent endangering the environment and personnel safety.
As for transportation, it should not be ignored. Before transportation, ensure that the packaging is complete and well sealed to avoid leakage during transportation. The means of transportation should be clean, dry, and equipped with fire and explosion-proof facilities. During transportation, it should be protected from exposure to the sun, rain, and high temperature. Transport personnel should be familiar with its dangerous characteristics and emergency treatment methods, and carry necessary emergency equipment and protective supplies. Strictly follow the specified route for transportation, and do not stop in densely populated areas or near important facilities.
2- (Bromomethyl) -1-chloro-4-fluorobenzene has a significant impact on the environment, personnel safety and its own stability during storage and transportation. It is necessary to strictly follow relevant norms and requirements, and must not be slack.

What are the security risks of 2- (Bromomethyl) -1-Chloro-4-Fluorobenzene?

2-%28Bromomethyl%29-1-Chloro-4-Fluorobenzene is 2- (bromomethyl) -1 -chloro-4 -fluorobenzene, which has multiple safety risks.
Looking at its chemical structure, bromomethyl is active and highly reactive. In chemical production operations, if you are not careful, it is easy to cause combustion or even explosion when exposed to heat, open flames or oxidants. This is a major fire and explosion hazard.
Furthermore, its halogen atoms, bromine, chlorine and fluorine are all toxic. If the human body inhales its volatile gases, or comes into contact with the skin or eats it by mistake, the poison will enter the body through the respiratory tract, skin or digestive tract, which will damage the respiratory tract, skin and digestive system. Long-term exposure may involve the nervous system and organs, causing chronic poisoning and damage health.
Strict safety regulations must be followed when producing, storing and transporting 2- (bromomethyl) -1 -chloro-4 -fluorobenzene. Storage should be placed in a cool and ventilated warehouse, away from fire and heat sources, and stored separately from oxidants and alkalis. Do not mix storage. Handling should be light and light to prevent package damage. When operating, operators should wear protective clothing, gloves and gas masks and other protective equipment to ensure safety.