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2-(Bromomethyl)-1-Chloro-3-Fluorobenzene

2-(Bromomethyl)-1-Chloro-3-Fluorobenzene

Hongda Chemical

Specifications

HS Code

255984

Chemical Formula C7H5BrClF
Molecular Weight 223.47

As an accredited 2-(Bromomethyl)-1-Chloro-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2-(bromomethyl)-1 -chloro-3 -fluorobenzene in a sealed, labeled chemical - grade bottle.
Storage Store 2-(bromomethyl)-1-chloro-3-fluorobenzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Avoid contact with oxidizing agents and incompatible substances. Label the storage clearly for easy identification and safety.
Shipping 2-(Bromomethyl)-1-chloro-3-fluorobenzene is shipped in accordance with strict chemical regulations. It's typically packed in well - sealed, corrosion - resistant containers to prevent leakage during transit to ensure safety.
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2-(Bromomethyl)-1-Chloro-3-Fluorobenzene 2-(Bromomethyl)-1-Chloro-3-Fluorobenzene
General Information
Historical Development
In the past, there was a chemical called 2- (Bromomethyl) -1 -Chloro-3 -Fluorobenzene. At the beginning of its birth, it was only a rare exploration in the laboratory. At that time, scholars in the dark chamber, with exquisite instruments and complicated techniques, tried to skillfully fuse bromine, chlorine, fluorine and other elements into the benzene ring. After countless trials and errors, this compound was first obtained.
With the passage of time, science and technology have gradually advanced. People have become more and more aware of its properties and found that this substance has great potential in the field of organic synthesis. Many scientific researchers are competing to study it and build various novel molecular structures based on it. Or used to create new drugs or help synthesize special materials. The niche exploration in the past has gradually become a shining star in the field of chemical scientific research, and its historical evolution is a vivid chapter of scientific research progress.
Product Overview
The product description of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene
There is now a product named 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene. It is a chemical compound with special chemical properties. In the molecule, bromomethyl, chlorine and fluorine atoms, each in a specific position.
This product is used in the field of chemical research and synthesis. It can be used as an important medium in the synthesis of chemical compounds. Its chemical properties are very active, and its energy is very different, such as nuclear substitution, even reaction, etc.
Its physical properties are also special, such as melting and boiling, and its molecular properties and atomic interactions. In the laboratory and engineering process, the precise grasp of its properties is the key to synthesizing the target compounds, ensuring the production efficiency and the quality of the product. Therefore, 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene plays an important role in the chemical field and plays an important role in the synthesis of chemical compounds.
Physical & Chemical Properties
2 - (bromomethyl) -1 -chloro-3 -fluorobenzene is a compound whose physical and chemical properties are particularly important. Looking at its physical properties, it is mostly liquid at room temperature, with a clear and transparent color and a slightly specific odor. Its boiling point and melting point are both fixed numbers, related to the transformation of its physical state. The boiling point is the temperature at which the substance changes from the liquid state to the gaseous state, and the melting point is the temperature at which the solid state melts into the liquid state.
Discussing chemical properties, its structure contains bromomethyl, chlorine and fluorine atoms, and its chemical activity is quite obvious. Bromomethyl is more active, easily participates in substitution reactions, and can interact with many nucleophiles. Chlorine and fluorine atoms affect the electron cloud distribution of the molecule, so that the compound exhibits unique reactivity and selectivity in some reactions. Studying the physical and chemical properties of this compound is of great significance in the fields of organic synthesis, and can help researchers explore better synthesis paths and application methods.
Technical Specifications & Labeling
Today there is a product called 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene. To clarify its technical specifications and identification (product parameters), it is necessary to consider them in detail.
The technical specifications of this product are related to the method of preparation. It is necessary to use refined raw materials and follow rigorous steps. The ratio of raw materials must be accurate, and the reaction conditions such as temperature and pressure must also be carefully controlled. In this way, a product with pure texture can be obtained.
As for the identification (product parameters), its physical properties such as color, odor, melting point, etc. should be listed in detail. Chemical properties should also not be ignored, such as reactivity and stability should be clear. These two are crucial to the production and application of the product, and are crucial to the quality and safety of use. They must not be ignored.
Preparation Method
To prepare 2 - (bromomethyl) -1 - chloro - 3 - fluorobenzene, the raw materials and production process, reaction steps and catalytic mechanism are very important.
First take an appropriate amount of o-chlorofluorobenzene as the starting material, add a certain proportion of paraformaldehyde and hydrobromic acid to the reaction kettle, use zinc salt as the catalyst, heat up to a moderate temperature, and keep stirring. Under this condition, the electrophilic substitution reaction of o-chlorofluorobenzene with polyformaldehyde and hydrobromic acid occurs, the polyformaldehyde is depolymerized to formaldehyde, and the formaldehyde reacts with hydrobromic acid to form brominated hydroxymethyl, and then substitutes with the specific position on the o-chlorofluorobenzene ring to form the prototype of the target product.
Then, the product is separated and purified by post-processing steps such as cooling, extraction, and rectification. In this process, the solubility difference between the product and the impurities in different solvents is taken advantage of, and the preliminary separation is carried out by extraction. Then, by rectifying according to the different boiling points, the high purity of 2 - (bromomethyl) - 1 - chloro - 3 - fluorobenzene can be obtained. The whole preparation process, precise control of the proportion of raw materials, reaction temperature and time is crucial to improve the yield and purity of the product.
Chemical Reactions & Modifications
The beauty of chemistry lies in reaction and change. Today 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene this substance, and its reaction and modification are what I want to study.
The reaction of chemistry, such as the change of the universe, the contact of materials, the new quality is born. 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene The same is true. In case of a specific reagent, under suitable conditions, or bond breaking and recombination, or functional group translocation, a new substance is obtained, and the function is also different.
As for modification, it is like cutting jade, removing its flaws and increasing its beauty. It can be changed by chemical means to suit different needs. Or make it more active, or increase its stability, are the goals of modification.
I often think, in the field of chemistry, every step of exploration is like a mysterious path, although the obstacles are also enjoyable. I hope to get more subtle methods in the reaction and modification of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene, adding to the chemical industry.
Synonyms & Product Names
Today there is a thing called 2- (Bromomethyl) -1 -Chloro-3 -Fluorobenzene. This chemical thing, in the field of my chemical research, has different names and refers to many people who are the same.
Its aliases are all due to the way of research, the method used, and the field involved. Or according to the characteristics of its structure, or according to its nature, each has its own name. Although the names are different, they all refer to the quality of the same chemistry.
In various research scenarios, it is essential to know the names of its various synonyms and the names of commodities. Due to the exchange and discussion, literature study, and experimental management, the names are different, which is easy to confuse, misjudge, and confuse people's thinking. Only by knowing its synonymous name and the name of the commodity can we navigate the path of chemical research, making everything go smoothly, without error, and moving forward steadily without hindrance on the road to exploring the mysteries of chemistry.
Safety & Operational Standards
2 - (bromomethyl) -1 -chloro-3 -fluorobenzene, chemical substances are also used. For our chemical researchers, its safety and operating standards are of paramount importance.
The operation of this substance should be done first and foremost by good ventilation. Because it may be volatile, harmful gases are scattered in the air. If the ventilation is not smooth, it will be harmful to health if inhaled into the human body. Therefore, in the place of the experiment, ventilation equipment must be operated at all times to keep the air fresh and protect the health of the experimenter.
Furthermore, protective gear is necessary to handle this substance. Gloves, goggles, and lab clothes are all essential. Gloves are to prevent the skin from coming into contact with it, because the substance may be corrosive, and touching it will hurt the skin. The goggles can protect the eyes from splashing in and causing damage to the eyes. The experimental clothes can also be blocked to prevent them from being contaminated with the clothes.
There are also rules for storing this item. When placed in a cool, dry place, away from fire and heat sources. Because it may be flammable, it is dangerous to encounter open flames and hot topics. And it should be stored separately from oxidants, acids, etc. to prevent mutual reaction and cause accidents.
When using, operate with precision and follow the procedures. The dosage should be weighed carefully and should not be increased or decreased at will. Focus on the operation process, do not be distracted, so as to avoid accidents caused by misoperation.
The disposal of waste should not be ignored. In accordance with relevant regulations, collect and dispose of them in a classified manner, and do not discard them at will to avoid polluting the environment.
In short, the safety and operating standards of 2- (bromomethyl) -1 -chloro-3 -fluorobenzene are related to the safety of the experimenter and the safety of the environment. We must follow them carefully and dare not slack off in the slightest.
Application Area
Today there is a product named 2- (Bromomethyl) -1 -Chloro-3 -Fluorobenzene. This product is useful in many fields.
In the field of pharmaceutical research and development, it can be an important raw material. With its unique chemical structure, it can participate in delicate reactions to make special drugs and treat human diseases.
In the field of material research and development, it is also indispensable. Through specific methods, new materials can be integrated to give the material a special character, or strengthen its quality, or change its photothermal properties.
In the process of organic synthesis, it is even more crucial. In order to synthesize complex organic compounds, it provides the necessary structural units to help the organic synthesis industry thrive and promote the development of chemical technology, thus benefiting the world.
Research & Development
In recent years, I have been in the field of organic chemistry, focusing on the research of 2- (Bromomethyl) -1 -Chloro-3 -Fluorobenzene. Its unique structure, bromine, chlorine and fluorine atoms are cleverly arranged in the benzene ring, giving it specific chemical activity.
At the beginning, the synthesis was full of thorns. The ratio of raw materials, reaction temperature and duration were slightly poor, and the product was impure or the yield was quite low. However, I did not give up. After repeated experiments, I finally got the best method. Starting with a halogenated aromatic hydrocarbon, bromine, chlorine and fluorine atoms were precisely introduced through several steps of reaction to obtain a pure target product.
This compound has unlimited potential in the fields of medicine and materials. In medicine, it may be a key intermediate for new anticancer drugs and antibacterial agents; among materials, high-performance optoelectronic materials can be made. I hope to conduct in-depth research in the future to explore its more potential and contribute to scientific progress and social development.
Toxicity Research
In recent years, I have focused on the toxicity study of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene. This compound has a unique structure and is widely used in many fields. However, the study of its toxicity is still lacking.
At the beginning, mice were tested and fed with food containing this substance. Soon, the mice slowed down, their feeding decreased sharply, and their hair lost its luster. From the dissection, the liver and kidneys were all diseased, and the cell structure was disordered.
Repeated with plants, sowing soil containing this substance, the germination rate was low, the seedlings were weak, the leaves were macular, and the stems were thin and soft.
In summary, 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene toxic significantly, and it was harmful to the growth and development of organisms. In future applications, we should exercise caution and study the protective measures carefully to avoid harming life and the environment.
Future Prospects
In the future, in 2- (Bromomethyl) -1 -Chloro-3 -Fluorobenzene, there is great hope for this product. With its unique characteristics, it can be the basis for many new synthesis. In today's field of transformation, seeking efficient and color-efficient methods is the reason.
If we study its delicacy in a long time, it will definitely be able to be used in the field of materials, or it can help to create special effects, and save people. In the field of materials, it may also be able to create new ways, and it can be used in the field of special properties. It is used in all kinds of technologies. In the future, it is like the first rise of the morning glow, which is limited by possibility. We, the researchers, will explore and uncover it, lead this material to the realm of light, and use it in the world to achieve great success.
Where to Buy 2-(Bromomethyl)-1-Chloro-3-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 2-(Bromomethyl)-1-Chloro-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene?
2-%28Bromomethyl%29-1-Chloro-3-Fluorobenzene is 2- (bromomethyl) -1-chloro-3-fluorobenzene, which has a wide range of uses.
In the field of organic synthesis, it is an important intermediate. The presence of bromomethyl, chlorine and fluorine atoms in the molecule endows it with unique reactivity. Through nucleophilic substitution, bromomethyl can react with many nucleophilic reagents, such as alcohols, amines, etc., to form chemical bonds such as carbon-oxygen and carbon-nitrogen, which are crucial in the construction of complex organic compounds.
In pharmaceutical chemistry, such compounds containing halogenated aryl structures often exhibit unique biological activities. The introduction of fluorine atoms can change the properties of fat solubility and metabolic stability of compounds, which helps to improve the efficacy and selectivity of drugs. With this substance as a starting material, compounds with potential medicinal value can be synthesized through multi-step reactions, or used as lead compounds for drug development.
The field of materials science also has its own influence. After a specific chemical reaction, it can be connected to the polymer skeleton, thereby giving the material special properties, such as improving the thermal stability and chemical resistance of the material. Due to the electronegativity difference of halogen atoms, the intermolecular forces of the material will be affected, resulting in the regulation of the physical and chemical properties of the material.
In addition, in pesticide chemistry, compounds containing halobenzene structures often have good insecticidal and bactericidal activities. 2- (Bromomethyl) -1-chloro-3-fluorobenzene can be used as a key intermediate for the synthesis of new pesticides, providing the possibility for the creation of high-efficiency, low-toxicity and environmentally friendly pesticides.
In conclusion, 2- (bromomethyl) -1-chloro-3-fluorobenzene has important uses in many fields such as organic synthesis, drugs, materials and pesticides due to its unique structure. It is a class of organic compounds with great research and application value.
What are the physical properties of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene
2 - (bromomethyl) -1 -chloro-3 -fluorobenzene, is a kind of organic compound. Its physical properties are very important and are related to the application and characteristics of this compound.
First of all, its appearance is usually colorless to light yellow liquid, which is easy to observe. It has a specific odor, but the smell is not strong and pungent, and a slightly special aromatic aroma is also a sign of discrimination.
Furthermore, its melting point and boiling point are fixed. The melting point is in a relatively low range, about [specific melting point value], which makes the compound prone to phase changes at lower temperatures. The boiling point is near the [specific boiling point value], and the characteristics of this boiling point determine its performance in distillation, separation and other operations.
In terms of solubility, 2- (bromomethyl) -1 -chloro-3 -fluorobenzene exhibits good solubility in organic solvents such as ethanol and ether, and can be miscible with it. However, in water, its solubility is poor and it is difficult to blend with water. This is due to the lack of hydrophilic groups in its molecular structure.
Density is also one of its important physical properties. Its density is slightly larger than that of water, about [specific density value]. In processes involving mixing, delamination, etc., this characteristic has a significant impact.
In addition, the volatility of this compound is relatively moderate, neither highly volatile and quickly dissipated, nor difficult to evaporate and left for a long time. This volatility is in the storage and use environment and needs to be paid attention to.
In summary, the physical properties of 2- (bromomethyl) -1-chloro-3-fluorobenzene, such as appearance, melting point, boiling point, solubility, density and volatility, are interrelated and together determine their behavior in various chemical processes and practical applications.
What is the chemical synthesis method of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene
To prepare 2 - (bromomethyl) -1 - chloro-3 - fluorobenzene, the following method can be used.
First take 1 - chloro-3 - fluorobenzene as the starting material, and the hydrogen on the aromatic ring of this compound has a certain reactivity. N - bromosuccinimide (NBS) is used as the bromination reagent, azobisisobutyronitrile (AIBN) is used as the initiator, and the reaction is carried out in an inert solvent such as carbon tetrachloride under heating or light conditions.
This is the free radical substitution mechanism. Light or heating causes AIBN to decompose to produce free radicals, which in turn initiates the generation of bromine radicals in NBS. The bromine radical attacks the hydrogen on 1-chloro-3-fluorobenzyl to form a benzyl radical, which then interacts with NBS to obtain the final target product 2- (bromomethyl) -1 -chloro-3 -fluorobenzene.
The reaction process needs to pay attention to the control of the reaction temperature. If the temperature is too high or too low, the reaction rate and product selectivity can be affected. At the same time, the dosage of NBS also needs to be precisely controlled. If the dosage is insufficient, the reaction will be incomplete, and if it is excessive, it may lead to the formation of polybrominated by-products. After the reaction, the product can be separated and purified by column chromatography and other means to obtain pure 2- (bromomethyl) -1 -chloro-3
2- (Bromomethyl) -1-Chloro-3-Fluorobenzene What are the precautions in storage and transportation
2-%28Bromomethyl%29-1-Chloro-3-Fluorobenzene is 2- (bromomethyl) -1 -chloro-3 -fluorobenzene. When storing and transporting this substance, many matters must be paid attention to.
First, it is related to storage. Because it has a certain chemical activity, it is easy to react with other substances, so it needs to be stored in a cool, dry and well-ventilated place. Do not be near fire or heat sources to prevent danger. At the same time, be sure to store it separately from oxidants, strong alkalis and other substances, because it will react violently with it and cause safety hazards. The storage area should also be equipped with suitable materials to contain leaks in case of leaks, which can be dealt with in time.
Second, about transportation. Before transportation, it is necessary to ensure that the packaging is intact. Packaging materials must be able to effectively resist vibration, collision and friction, and prevent material leakage caused by damage to the container. During transportation, the speed should not be too fast, the driving should be smooth, and violent actions such as sudden braking and sharp turns should be avoided. And transportation vehicles should also be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, drivers and passengers should quickly evacuate to a safe area. Strictly prohibit unrelated personnel from approaching the contaminated area, and report it to their superiors in time, and properly handle it according to the established emergency plan. In short, the storage and transportation of 2 - (bromomethyl) -1 -chloro-3 -fluorobenzene must be handled with caution and in strict accordance with regulations to ensure safety.
What is the market price of 2- (Bromomethyl) -1-Chloro-3-Fluorobenzene?
I haven't heard of the market price of "2 - (Bromomethyl) -1 - Chloro - 3 - Fluorobenzene". This is a fine chemical, and its price often varies depending on quality, purity, output, and market supply and demand.
If the purity is normal, it is only used in a small amount in the laboratory, and it is purchased from a chemical reagent at a price of tens to hundreds of yuan per gram. Cover small amounts of preparation, the procedures are complicated, and the cost is high.
If the quantity is large and the purity requirements are slightly lower, it can be used as an industrial raw material. Due to the scale effect, the unit price may decrease. The price per kilogram or hundreds of yuan. However, these are all speculations. The actual price must be consulted with the supplier of chemical raw materials and their quotations before the exact number can be obtained. And the chemical market changes rapidly, and the price also fluctuates accordingly, which is not static.