2-%28Bromomethyl%29-1%2C4-Difluorobenzene is 2- (bromomethyl) -1,4-difluorobenzene, which has a wide range of uses.
In the field of organic synthesis, it is often a key intermediate. Due to its structure having both bromomethyl and difluorobenzene structures, bromomethyl is very active and can interact with various nucleophiles through many reactions, such as nucleophilic substitution reactions. If the nucleophilic reagent is an alcohol, under appropriate conditions, the bromine atom can be replaced by an alcoholoxy group to form ether compounds containing difluorobenzene structures. Such ether compounds may exhibit special properties in the fields of medicine and materials.
In the field of pharmaceutical chemistry, molecules with specific biological activities can be constructed by using this substance as a starting material and modifying it through multi-step reactions. Due to its fluorine-containing atoms, it can enhance the lipid solubility of molecules, which is conducive to drug penetration through biofilms and improves bioavailability. For example, after design and modification, inhibitors targeting specific disease targets can be prepared, opening up new directions for drug research and development.
In the field of materials science, fluorine-containing functional polymers can be prepared by polymerizing with other monomers through the reactivity of bromomethyl. Such materials may have unique physical and chemical properties, such as excellent chemical resistance and low dielectric constant. In electronic materials, fluorine-containing polymers with low dielectric constant can be used to fabricate high-performance printed circuit boards and improve the performance of electronic devices. With its unique structure, 2- (bromomethyl) -1,4-difluorobenzene has important applications in organic synthesis, medicinal chemistry, materials science and other fields, laying the foundation for many research and applications.

2-%28Bromomethyl%29-1%2C4-Difluorobenzene is 2- (bromomethyl) -1,4-difluorobenzene, which has special physical properties. Under normal temperature and pressure, it is mostly colorless to light yellow liquid, and it is clear and transparent. This state makes it easy to flow, and the light shines on it, and the visible luster flows.
When it comes to the boiling point, it is about 190-192 ° C. When the temperature rises gradually, the thermal motion of the molecules intensifies, breaks free from the liquid phase and turns into a gaseous state. The melting point is relatively low, about -20 ° C. At this temperature, the molecular arrangement tends to be orderly, from liquid to solid.
Its density is slightly larger than that of water, about 1.66 g/cm ³. If it is placed in a container with water, it can be seen that it sinks to the bottom of the water, like a ghost of water, and the two are distinct. And it has a certain refractive index, about 1.518-1.520. When light passes through, the path is deflected, which is also one of its physical characteristics.
And because its molecular structure contains bromomethyl and difluorophenyl, its solubility is unique. It is soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc., in which it is like a duck to water, and the molecules are uniformly dispersed. However, in water, the solubility is very small, and the two are like foreign visitors and difficult to blend. This difference in solubility is of great significance in the separation, purification, and selection of media for chemical reactions.

2 - (bromomethyl) -1,4-difluorobenzene is an important compound in organic synthesis. There are many common methods for its synthesis.
First, 1,4-difluorobenzene is used as the starting material. First, 1,4-difluorobenzene is reacted with polyformaldehyde and hydrobromic acid under specific conditions. In this reaction, polyformaldehyde is depolymerized to formaldehyde, and under the action of hydrobromic acid, 1,4-difluorobenzene is alkylated by Fu-g, and bromomethyl is introduced at a specific position in the benzene ring to obtain the target product. When reacting, pay attention to the reaction temperature, the proportion of reactants and other conditions. If the temperature is too high, it may cause more side reactions and reduce the yield; if the ratio is improper, it also affects the reaction process and product purity.
Second, it can be started from 1,4-difluorobenzoic acid. First reduce 1,4-difluorobenzoic acid to 1,4-difluorobenzyl alcohol, a commonly used reducing agent such as sodium borohydride. 1,4-difluorobenzyl alcohol is then reacted with halogenating reagents such as hydrobromic acid or phosphorus tribromide, and the hydroxyl group is replaced by a bromine atom to obtain 2- (bromomethyl) -1,4-difluorobenzene. In this path, the reduction step needs to control the amount of reducing agent and reaction time to prevent excessive reduction; the halogenation step should pay attention to the activity and reaction conditions of the halogenated reagent to ensure the selectivity and yield of the product.
Or, using benzene derivatives containing suitable substituents as raw materials, fluorine atoms and bromomethyl are gradually introduced through multi-step reactions. However, there are many steps in this path, and each step of the reaction needs to be carefully planned, and the reaction conditions should be strictly controlled to avoid side reactions and improve the yield and purity of the target product. The method of synthesizing 2- (bromomethyl) -1,4-difluorobenzene has its own advantages and disadvantages. In practical application, when considering factors such as raw material availability, cost, yield and purity requirements, choose carefully.

2-%28Bromomethyl%29-1%2C4-Difluorobenzene is 2- (bromomethyl) -1,4-difluorobenzene. When storing and transporting this substance, many matters need to be paid attention to.
It has certain chemical activity, and bromomethyl is active. When storing, make sure that the container is well sealed to prevent it from contacting with air and water vapor. Because it encounters water vapor or triggers reactions such as hydrolysis, it causes the product to deteriorate. And it should be placed in a cool, dry and ventilated place, away from fire and heat sources. This substance can easily exacerbate the reactivity when heated, and even cause hazards such as combustion and explosion.
During transportation, strict specifications must also be followed. The packaging must be strong and tight, which can resist vibration, collision and friction, and avoid material leakage caused by container damage. The means of transport should be clean and dry, with no other substances that can react with it. When loading and unloading, the operation should be gentle, and it is strictly forbidden to throw or collide to prevent damage to the packaging.
Furthermore, whether it is storage or transportation, it should be strictly marked. Clearly indicate its chemical name, dangerous nature and other information, so that the relevant personnel can see at a glance, so as to take appropriate protection and emergency measures. At the same time, the relevant operators should be professionally trained, familiar with its characteristics and safety precautions, so as to ensure the safety of 2- (bromomethyl) -1,4-difluorobenzene during storage and transportation, and avoid accidents.

The market price of 2 - (bromomethyl) -1,4-difluorobenzene is difficult to determine, because of the intertwined influence of many factors.
The price of raw materials is the key. If the source of bromine and difluorobenzene is scarce, or the supply is blocked due to natural and man-made disasters or geopolitics, the price of raw materials will rise, which will increase the cost of 2 - (bromomethyl) -1,4-difluorobenzene, and the market price will also rise. On the contrary, if the raw materials are abundant, the price will stabilize and fall.
Furthermore, the preparation method also affects its price. If the process is complicated, multiple processes, expensive equipment and fine control are required, which consumes huge manpower and material resources, and the price of the product will be high. However, the new method of simplicity and efficiency is created, saving costs and increasing efficiency, and the price can also be close to the people.
The situation of market supply and demand is also the main reason. If the electronics, pharmaceutical and other industries have strong demand for it, but the supply is limited, the demand exceeds the supply, and the price is like an arrow, and it has to rise. On the contrary, if the supply exceeds the demand, merchants will reduce their prices to compete for the market in order to sell their goods.
The difference in regions also makes the price different. In places with developed economies and concentrated demand, prices may vary due to convenient transportation and active markets. And different taxes and policies in different places also affect costs and prices.
Combined with various factors, the market price of 2- (bromomethyl) -1,4-difluorobenzene fluctuates erratically. Today, it is difficult to determine its exact price without knowing the details of raw materials, processes, supply and demand, or hovering between tens of yuan and hundreds of yuan per kilogram. However, this is only speculation, not an exact number.