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2-Bromo-5-Fluoroiodobenzene

2-Bromo-5-Fluoroiodobenzene

Hongda Chemical

Specifications

HS Code

446025

Chemical Formula C6H3BrFI
Molecular Weight 301.896
Appearance Solid (Typical)
Cas Number 100384-63-6
Boiling Point 248.5 - 249.5 °C at 760 mmHg (Estimated)
Density 2.463 g/cm³ (Estimated)
Flash Point 104.1 °C (Estimated)
Refractive Index 1.655 (Estimated)
Solubility Soluble in organic solvents like dichloromethane, chloroform
Storage Conditions Store in a cool, dry place, away from oxidizing agents

As an accredited 2-Bromo-5-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 2 - bromo - 5 - fluoroiodobenzene packaged in a sealed glass bottle.
Storage 2 - bromo - 5 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping 2 - bromo - 5 - fluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical transport regulations to ensure safety during transit, safeguarding against spills and environmental hazards.
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2-Bromo-5-Fluoroiodobenzene 2-Bromo-5-Fluoroiodobenzene
General Information
Historical Development
Husband 2 - Bromo - 5 - Fluoroiodobenzene, the thing of transformation is also. The beginning, in the field of transformation, the study of physical properties, the exploration of the method of synthesis. For the first time, if you want to obtain this thing, if you go to the sky, you can't do it, or you can't, or you can't measure it.
Those who are in the field of science, Today, this thing is no longer rare in the world. It is the hard work of those who transform the world. Only then can this achievement be achieved, and its development can be achieved.
Product Overview
2 - Bromo - 5 - Fluoroiodobenzene is a unique organic compound. Its molecular structure is exquisite, containing bromine (Bromo), fluorine (Fluoro) and iodine (iodo) atoms, arranged in order on the benzene ring. This compound has unique physical and chemical properties and is widely used in the field of organic synthesis.
Because of its halogen atom properties, it can be used as a key intermediate and participate in many chemical reactions. In nucleophilic substitution reactions, bromine and iodine atoms can be replaced by various nucleophilic reagents to form novel carbon-heteroatomic bonds, laying the foundation for the creation of complex organic molecules. The introduction of fluorine atoms also significantly changes the electron cloud density and spatial structure of compounds, affecting their biological activities and physical properties, and has great potential in the fields of medicinal chemistry and materials science.
The method of preparing 2 - Bromo - 5 - Fluoroiodobenzene relies on the organic halogenation reaction. By precisely adjusting the reaction conditions and the proportion of reagents, the product with high yield and purity can be obtained. However, the synthesis process needs to pay attention to the selectivity of the reaction and the inhibition of side reactions in order to achieve the ideal synthesis effect.
Physical & Chemical Properties
2 - Bromo - 5 - Fluoroiodobenzene is an organic compound, and its physicochemical properties are crucial. This compound is liquid at room temperature, with a nearly colorless color and a special odor. Looking at its physical properties, the boiling point is quite high, about [X] ° C, which indicates that the intermolecular force is strong. The melting point is around [X] ° C, reflecting its lattice structure characteristics.
In terms of chemical properties, it is highly active due to the existence of three halogen atoms: bromine, fluorine and iodine. Bromine atoms change the electron cloud density of the benzene ring, which is prone to electrophilic substitution reactions. Fluorine atoms have high electronegativity, which enhances molecular polarity and affects reaction activity and selectivity. Although iodine atoms are relatively stable, they can also participate in reactions under specific conditions, such as coupling reactions, and are widely used in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a thing called 2 - Bromo - 5 - Fluoroiodobenzene. In the preparation of techniques, it is necessary to abide by the procedures. The choice of raw materials must be pure and good, and the degree of proportions must be accurate. When reacting, the control of temperature and humidity is all about success or failure.
As for the distinction of quality, the appearance should be uniform and colorless. Measuring the point of melting and boiling should be in line with the established standard. According to the method of spectroscopy, the peak position and peak strength are in line with its inherent characteristics, and it is a qualified product. The amount of impurities must be limited to a small amount to prevent damage to its quality. By strictly adhering to these rules and regulations, excellent 2-Bromo-5-Fluoroiodobenzene can be prepared to meet all requirements.
Preparation Method
The method of making 2 - Bromo - 5 - Fluoroiodobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, fluorobenzene is taken as the base material, and brominated. Bromofluorobenzene is obtained by using bromine and an appropriate catalyst to connect bromine atoms to the benzene ring at a suitable temperature and pressure.
times, the bromofluorobenzene is introduced into the iodine group. Using an iodine reagent, combined with a specific catalytic system, and through a reaction such as nucleophilic substitution, the iodine atoms are precisely connected to the target position. The reaction steps need to be carefully controlled, and the reaction conditions of each step, such as temperature, time, and the proportion of reactants, are all critical.
The catalytic mechanism should not be underestimated. The selected catalyst can reduce the activation energy of the reaction and promote the efficient progress of the reaction. Or use a metal catalyst, with its unique electronic structure, to stabilize the transition state of the reaction and increase the reaction rate. In this way, after various steps and controls, 2-Bromo-5-Fluoroiodobenzene products can be obtained.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 2-Bromo-5-Fluoroiodobenzene, and its chemical reaction and change are quite important to scholars. The reaction of this compound often depends on the characteristics of the atoms in its molecules. Atoms such as bromine, fluorine, and iodine each have their own characteristics and play a key role in the reaction.
Its reaction path may vary depending on the difference of reagents and the change of conditions. When encountering a certain reagent, it may trigger a substitution reaction, the atom is translocated, and the structure is changed. Or under a specific temperature and pressure, the molecules are rearranged to obtain a new structure, and the properties also change accordingly.
Observing its change shows the law of chemistry, which is also the basis for synthesizing new compounds and improving their properties. Scholars study this with the hope of accurately controlling their reactions, obtaining the desired products, and applying them in the fields of materials and medicine to promote the advancement of science and technology and the goodness of life.
Synonyms & Product Names
2 - Bromo - 5 - Fluoroiodobenzene, the synonym and trade name of this substance, is an important item in my chemical research. Its synonym can be called "2 - bromo - 5 - fluoroiodobenzene", according to the chemical nomenclature, according to the order of its elements and atoms. The trade name varies according to the manufacturer and the market, or has a unique name to recognize its quality.
In my research process, the characteristics of this compound are remarkable. Its structure contains bromine, fluorine, iodine and other halogen elements, giving it unique chemical activity. The activity of bromine, the stability of fluorine, and the special reactivity of iodine are combined in a benzene ring, which makes the reaction diverse. Or in organic synthesis, it can be used as a key intermediate, and through the reaction of substitution and coupling, it can form complex organic molecules, laying the foundation for the fields of medicine and materials science. Therefore, the clarity of its synonyms and trade names is of great significance in research and application, helping researchers to determine the substances involved and conduct experiments and explorations.
Safety & Operational Standards
2 - Bromo - 5 - Fluoroiodobenzene Safety and Operating Specifications
2 - Bromo - 5 - Fluoroiodobenzene is an important chemical substance that is widely used in research and production. In order to ensure the safety of personnel and the smooth progress of experiments and production, the following safety and operating specifications must be strictly followed.
#1. Storage Safety
This substance should be stored in a cool, dry and well-ventilated place, away from fire and heat sources to prevent danger. It should be stored separately from oxidants, acids, bases, etc., and should not be mixed in storage to avoid chemical reactions caused by interactions. The storage area should be equipped with suitable materials to contain objects that may leak.
#2. Operating Specifications
Operators must undergo special training and strictly abide by the operating procedures. When operating, appropriate protective equipment should be worn, such as protective glasses, protective gloves and gas masks, to prevent substances from contacting the skin and eyes, and to avoid inhaling their volatile gases.
Operate in a fume hood to ensure good ventilation and reduce the concentration of volatile substances in the air. When taking the substance, the action should be cautious to prevent spillage. In the event of spillage, emergency measures should be taken immediately. When a small amount of leakage is spilled, it can be absorbed by inert materials such as sand and vermiculite and collected in a closed container; when a large amount of leakage is spilled, an embankment should be built or a pit should be dug for containment, and it should be transferred to a tanker or a special collector with a pump for recycling or transportation to a waste treatment site for disposal.
#3. Emergency treatment
If you accidentally touch the skin, you should immediately take off the contaminated clothes, rinse with a large amount of flowing water for at least 15 minutes, and seek medical treatment. If you come into contact with the eyes, you should immediately lift the eyelids and rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes. Medical treatment is also required. If inhaled, should quickly leave the scene to fresh air, keep the airway unobstructed, such as breathing difficulties, give oxygen, such as breathing stop, immediately perform artificial respiration, and seek medical attention.
The above safety and operating standards are the key to ensure the safety of personnel and the smooth development of related work, must be strictly observed, not slack.
Application Area
2 - Bromo-5 - Fluoroiodobenzene is also a chemical substance. Its application is not limited. In the field of synthesis, this compound is often an important raw material. Due to its special properties, it can be used to generate a variety of chemical reactions, helping to form chemical molecules with specific biological activities.
In the field of materials, it also has its application. It can be repaired by chemistry, introducing specific functionalities to control the properties of materials, such as light properties.
And in the research of synthesis, 2 - Bromo-5 - Fluoroiodobenzene can be filled in the field of synthesis, helping to synthesize a variety of chemical compounds, and promoting the synthesis of chemical synthesis technology. In addition, it is important in many fields, and it is indispensable for the development of research and development.
Research & Development
There is a substance today, called 2-Bromo-5-Fluoroiodobenzene. As a chemical researcher, I have dedicated myself to studying this substance for a long time.
Looking at its properties, its structure is unique. Bromine, fluorine and iodine atoms coexist on the benzene ring and interact with each other, resulting in its unique chemical activity. In the reaction, due to its halogen atom properties, it can participate in various substitution reactions, or nucleophilic, or electrophilic, all of which can be used.
Study its application in the field of pharmaceutical synthesis, with extraordinary potential. It can be used as a key intermediate to construct the molecular structure of special drugs, which is expected to overcome difficult diseases. In the field of materials science, modified by specific reactions, or materials with special photoelectric properties can be prepared to meet the needs of scientific and technological development.
We should continue to study, explore more possibilities, and strive to promote this substance from research to wide application, contribute to the development of chemistry and the progress of society, and achieve a leap from research to development.
Toxicity Research
The research of chemical compounds is related to the health of life and the peace of the world. Now take 2 - Bromo - 5 - Fluoroiodobenzene as an investigation to investigate its toxicity in detail.
The toxicity of this substance must be investigated carefully. Although it is invisible and colorless, it will cause disaster if it enters the body. Or damage the viscera, disrupt the circulation of qi and blood; or harm the meridians and collaterals, causing injury to the spirit. Looking at its structure, bromine, fluorine, and iodine are all gathered in a benzene ring, and its strong nature can be seen.
In the context of experiments, try it with various objects. Small animals often feel uncomfortable, or listless, or lose their diet when they touch it. This shows its toxicity. And this thing is in the environment, it is also difficult to solve itself, and it will cause disaster to all things.
Therefore, when studying the toxicity of this thing, we should be very careful to prevent its harm from flowing into the world, to protect the well-being of the public, and to protect the environment in peace.
Future Prospects
Husband 2 - Bromo - 5 - Fluoroiodobenzene, the thing that transforms. I have studied this, and I have a vision for the future, and my heart is full of hope.
This material nature is special, or it can be used for new research. In today's world, there are many diseases and diseases, and new ones need to be cut. It may be a sharp weapon that can resist diseases, and help those who are born. And in the field of materials, it is also expected to be revealed. The demand for new materials, or already, is an important angle for the improvement of materials, to make utensils more and more clever.
The road ahead is long, unknown. However, I believe that the heart and strength of the master, the steps of the skill, 2 - Bromo - 5 - Fluoroiodobenzene will be able to develop its talents, and it will be used in the world to benefit people.
Where to Buy 2-Bromo-5-Fluoroiodobenzene in China?
As a trusted 2-Bromo-5-Fluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-5-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-5-Fluoroiodobenzene?
2-Bromo-5-fluoroiodobenzene is also a key intermediate in organic synthesis. It has a wide range of uses and is particularly important in the field of medicinal chemistry.
First, in the creation of new drugs, 2-bromo-5-fluoroiodobenzene plays a cornerstone effect. Drug developers can derive many compounds with unique pharmacological activities by ingeniously modifying their chemical structures. For example, it can be introduced into the molecular structure of a specific drug, and the interaction between the drug and the target can be optimized by adjusting the electron cloud distribution of the molecule, spatial resistance and other factors, thereby improving the efficacy and selectivity of the drug. Like targeted therapeutic drugs for certain diseases, the key structural fragments may be derived from the derivatization of 2-bromo-5-fluoroiodobenzene, which allows the drug to precisely act on diseased cells and reduce damage to normal cells.
Second, in the field of materials science, 2-bromo-5-fluoroiodobenzene also has extraordinary performance. When preparing functional materials, because they contain halogen atoms such as bromine, fluorine, and iodine, these halogen atoms endow molecules with unique electronic properties and reactivity. Taking the preparation of photoelectric materials as an example, using them as starting materials can construct polymers or small molecule materials with special photoelectric properties through a series of reactions. Such materials may have applications in organic Light Emitting Diodes (OLEDs), solar cells, etc., which can improve key performance indicators such as charge transfer efficiency and luminous efficiency of materials.
Furthermore, in the study of organic synthesis methodologies, 2-bromo-5-fluoroiodobenzene is often selected as a model substrate. Chemists use different types of chemical reactions to study them, such as nucleophilic substitution reactions, metal-catalyzed coupling reactions, etc., to explore new reaction paths and reaction conditions. Through in-depth exploration of these reactions, the methods and strategies of organic synthesis can be enriched, and new ideas and methods for synthesizing more complex organic compounds can be provided.
In summary, although 2-bromo-5-fluoroiodobenzene is an organic compound, it plays an important role in many fields such as medicine, materials and organic synthesis, and promotes the development of scientific research and technological innovation in various fields.
What are the physical properties of 2-Bromo-5-Fluoroiodobenzene?
2-Bromo-5-fluoroiodobenzene is also an organic compound. It has unique physical properties, which are related to melting point, boiling point, density, and solubility.
The melting point of this substance is specific, but the exact value has not been checked in detail. The melting point is the temperature at which a substance changes from a solid state to a liquid state. It is a key indicator in the process of chemical engineering, scientific research preparation and purification. Knowing its melting point can determine the purity of the substance and is also an important basis for controlling the reaction conditions.
The boiling point is also an important physical property. Although its specific boiling point is unknown, the level of boiling point is related to the intermolecular force. The presence of bromine, fluorine and iodine atoms in the molecule of 2-bromo-5-fluoroiodobenzene causes the intermolecular forces to be unusual, resulting in a specific boiling point state. The boiling point is crucial in operations such as distillation and separation, and different components in the mixture can be separated according to the difference in boiling points.
In terms of density, 2-bromo-5-fluoroiodobenzene has a specific density due to the type and arrangement of atoms. Density can help in the identification of substances, and also needs to be considered when separating liquids or designing reaction devices. Its density or due to the heavier characteristics of halogen atoms is higher than that of ordinary benzene derivatives.
In terms of solubility, this compound has a certain polarity due to halogen atoms, and has good solubility in organic solvents, such as common ether and dichloromethane. However, in water, due to its non-polar benzene ring structure and the hydrophobicity of halogen atoms, the solubility is not good. The solubility characteristics have a great impact on the selection of reaction solvents and the separation and extraction of products.
In short, the physical properties such as melting point, boiling point, density and solubility of 2-bromo-5-fluoroiodobenzene are of great significance in many fields of organic synthesis, analysis and detection. Although the exact value is not fully known, the trend and influence of its properties can provide guidance for scientific research and production practice.
What are 2-Bromo-5-Fluoroiodobenzene synthesis methods?
There are various ways to synthesize 2-bromo-5-fluoroiodobenzene. One can start from halogenated aromatics and obtain it by nucleophilic substitution reaction. First, take the aromatic hydrocarbon containing the appropriate substituent, use a brominating reagent, such as liquid bromine and iron powder catalytic system, to replace the bromine atom at a specific position, and then introduce the fluorine atom. Nucleophilic fluorinated reagents can be used to react under suitable conditions. As for the introduction of iodine atoms, iodizing reagents are often used in an appropriate reaction environment, and the target product can be obtained through substitution steps.
Second, metal catalytic coupling reaction can also be used. The aryl halides containing bromine and fluorine are used as raw materials and coupled with iodine substitutes under the action of metal catalysts such as palladium catalysts. This process requires fine regulation of reaction conditions, such as temperature, ligand selection, etc., to improve the selectivity and yield of the reaction. The choice of reaction solvent is also critical, and common organic solvents such as toluene, N, N-dimethylformamide, etc. provide good reaction media.
Furthermore, starting from aromatic derivatives, through multi-step functional group conversion. First construct a partial substituent, and gradually introduce bromine, fluorine and iodine atoms through a series of reactions such as oxidation, reduction, and substitution. Follow a reasonable reaction sequence and conditions to achieve the purpose of synthesizing 2-bromo-5-fluoroiodobenzene. Each step of the reaction needs to be precisely controlled and the reaction process monitored to obtain a pure and high-yield product.
What 2-Bromo-5-Fluoroiodobenzene need to pay attention to when storing and transporting
2-Bromo-5-fluoroiodobenzene is an organic compound. When storing and transporting, the following rules should be followed to ensure safety.
First, the storage place must be dry and cool. This compound is afraid of moisture and is prone to reaction and deterioration in case of moisture. Therefore, choose a dry place to avoid its contact with water vapor. A cool environment can reduce the risk of decomposition or other adverse reactions due to excessive temperature. The warehouse temperature should be controlled within a specific range and should not be too high.
Second, when stored and transported separately with oxidizing agents, reducing agents and strong bases. 2-Bromo-5-fluoroiodobenzene is chemically active and coexists with the above-mentioned substances. It is easy to react violently, or cause combustion and explosion. If the oxidant has strong oxidizing properties, contact with it or cause an oxidation reaction, resulting in an accident.
Third, the packaging must be tight and sturdy. Choose suitable packaging materials to prevent leakage and collision. If the packaging is damaged, the compound may leak out, polluting the environment and endangering personnel. Commonly used glass bottles, plastic bottles or special metal containers, depending on the quantity and transportation needs, must be well sealed.
Fourth, during transportation, drive steadily and slowly, and absorb vibration and dynamic impact. Violent vibration or damage to the packaging, compound leakage. And the means of transportation should be equipped with corresponding fire and emergency equipment to prepare for emergencies.
Fifth, clear warning signs should be set up at storage and transportation places. Show people that this is a chemical, there is potential danger, so that personnel can operate cautiously and be familiar with emergency response methods.
In summary, the storage and transportation of 2-bromo-5-fluoroiodobenzene requires strict attention in terms of environment, isolation, packaging, driving and labeling to ensure the safety of the whole process.
What is the market price of 2-Bromo-5-Fluoroiodobenzene?
The market price of 2-bromo-5-fluoroiodobenzene is difficult to determine. This is because the market price often changes due to various factors, and the price of this product is not listed in Tiangong Kaiwu. However, the influencing factors can be inferred to show that the price is approximate.
First, the cost of raw materials is the key. The difficulty and price of preparing the raw materials for 2-bromo-5-fluoroiodobenzene all affect the price of the final product. If the raw materials are scarce and difficult to find, or the preparation is cumbersome, the cost will be high, and the price of the product will also rise.
Second, the complexity of the preparation process also affects. If the synthesis requires delicate steps, special conditions or high-end equipment, the process cost will increase, and the price will rise. Fine and difficult synthesis often requires skilled craftsmen and advanced equipment, which are all cost components.
Third, the market supply and demand situation is an important factor. If there is strong demand for 2-bromo-5-fluoroiodobenzene in many industries, but the supply is limited, the price will rise according to the rationale of rarity; on the contrary, if the supply exceeds the demand, the merchant will sell the goods, or the price will be reduced.
Fourth, regional differences cannot be ignored. In different places, due to different economic levels, transportation costs, and policies, prices may vary. In prosperous cities, the demand is large and the logistics is convenient, or the price is slightly higher; in remote places, the price may vary due to inconvenient transportation, etc.
Overall, the market price of 2-bromo-5-fluoroiodobenzene may fluctuate within a certain range, ranging from a few taels of silver per catty to dozens of taels, depending on the dynamics of the above factors.