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2-Bromo-5-Fluoro-1,3-Dimethylbenzene

2-Bromo-5-Fluoro-1,3-Dimethylbenzene

Hongda Chemical

Specifications

HS Code

521348

Chemical Formula C8H8BrF
Molar Mass 203.05 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 197 - 198 °C
Melting Point N/A
Density 1.43 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 78 °C
Vapor Pressure Low vapor pressure at room temperature
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 2-Bromo-5-Fluoro-1,3-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - bromo - 5 - fluoro - 1,3 - dimethylbenzene packaged in a sealed glass bottle.
Storage 2 - bromo - 5 - fluoro - 1,3 - dimethylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics, to prevent leakage and contamination.
Shipping 2 - bromo - 5 - fluoro - 1,3 - dimethylbenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safe transit, avoiding exposure and potential environmental or safety risks.
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2-Bromo-5-Fluoro-1,3-Dimethylbenzene 2-Bromo-5-Fluoro-1,3-Dimethylbenzene
General Information
Historical Development
In the past, the study of chemical substances has gradually flourished in the world. 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene, its origin can also be traced.
At the beginning, the sages worked hard in the field of chemistry, exploring the properties of substances and changing rules. With the progress of research, the understanding of this compound gradually deepened. Early experiments, many twists and turns, to understand its structure and sexual characteristics, can not be done overnight.
Over the years, the technology is more refined, and the research method is also new. Scholars can better analyze its components and characteristics, and they can also make progress in the process of synthesis. From the beginning of ignorance and exploration, to the later preparation of this compound, the development of this compound has witnessed the growth of chemical technology. Its use in chemical, pharmaceutical and other industries has gradually emerged. It is an essential material for various research and production. Over time, it has become an indispensable thing in the field of chemistry.
Product Overview
Today there is a substance called 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene. This is an organic compound. In its structure, on the benzene ring, bromine atoms, fluorine atoms and dimethyl atoms are in specific positions.
Bromine, halogen elements are also active, and can often participate in various reactions in compounds, or nucleophilic substitution, or initiate free radical reactions. Although fluorine atoms are small, they are highly electronegative, which significantly affects the polarity and chemical activity of molecules. The existence of dimethyl also affects the spatial structure and physicochemical properties of molecules, such as its boiling point and solubility.
This substance is of great value in the field of organic synthesis. It can be used as a key intermediate. After a series of chemical reactions, it is converted into organic molecules with more complex structures and different functions. It is used in medicine, materials, and many other fields. It is also an important substance for chemical research and industrial production.
Physical & Chemical Properties
2-Bromo-5-Fluoro-1,3-Dimethylbenzene is also an organic compound. Its physical and chemical properties are worth studying.
Looking at its physical properties, under room temperature, it is often a colorless liquid with a special odor. Its boiling point and melting point are fixed, the boiling point is about [X] ° C, and the melting point is about [X] ° C. The density is moderate, about [X] g/cm ³, insoluble in water, but miscible in most organic solvents, such as ethanol, ether and the like.
On its chemical properties, the substitution of bromine, fluorine and methyl on the benzene ring gives it a unique reactivity. It can participate in electrophilic substitution reactions. Due to the electronegativity of fluorine and bromine, the electron cloud density distribution of benzene ring changes, resulting in different reaction check points from ordinary benzene derivatives. Methyl groups can also undergo oxidation and other reactions under specific conditions. The physicochemical properties of this compound may be important in organic synthesis and other fields, and should be investigated in detail.
Technical Specifications & Labeling
Today there is a thing called 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene. Its production method should follow the technical specifications. To make this thing, you need to prepare all kinds of materials, according to a certain ratio. In a clean vessel, put each material in sequence, and the temperature and humidity between them should also be carefully controlled.
Its quality identification is related to commercial parameters. Looking at its color, it should be a pure color, with no variegated colors mixed in. Smell its smell, it should have a specific smell, without odor disturbance. Measure its purity, when it reaches a certain standard, the amount of impurities must be within the specified range. In this way, meeting the requirements of technical specifications and quality identification (commercial parameters) can be a good product.
Preparation Method
To prepare 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene, the raw materials and production process, reaction steps and catalytic mechanism are very important.
First take an appropriate amount of 1,3 - dimethyl benzene and place it in a clean reactor. In a specific ratio, slowly add the reagent containing bromine and fluorine, which is the key starting material. The reaction temperature needs to be precisely controlled in a certain range and fine-tuned according to the reaction process.
The reaction steps are as follows. First, the raw materials are fully mixed under mild stirring to induce the initial reaction. Then, the temperature is raised to a certain node to accelerate the reaction, and the bromine and fluorine atoms are precisely replaced in a specific position of the benzene ring.
In terms of catalytic mechanism, specific catalysts are introduced, which can effectively reduce the activation energy of the reaction and speed up the reaction rate. The catalyst and the reactants form an intermediate transition state, which helps the fracture and formation of chemical bonds.
When the reaction reaches the expected level, a series of post-processing processes, such as extraction and purification, are used to obtain high-purity 2-Bromo-5-Fluoro-1,3-Dimethylbenzene products. This preparation method requires fine control of each link to ensure product quality and yield.
Chemical Reactions & Modifications
2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene is an important raw material for organic synthesis. Its chemical synthesis reaction and modification research are related to the improvement of the performance of this product and the development of new uses.
The synthesis reaction in the past may have harsh reaction conditions and unsatisfactory yield. However, today's chemical research strives to optimize the reaction path. If the catalyst is carefully screened, the reaction can be carried out efficiently and energy consumption can be reduced. Some scholars use special metal complexes as catalysts to make the reaction smooth under mild conditions, and the yield can be greatly improved.
Furthermore, in terms of modification, chemists optimize its chemical properties by introducing specific functional groups to change the distribution of its electron cloud. This move not only enhances its stability, but also finds new application opportunities for the product in the fields of medicine and materials. Chemical researchers are determined to promote the development of 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene, and unswervingly explore the subtlety of chemical reactions and modifications.
Synonyms & Product Names
2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene is very important in my chemical research. Its synonymous names are also expressed in many ways. Or according to its chemical structure characteristics, there are different names. As for trade names, the industry also has specific names.
I look at the classics. In the past, although the means of chemical research were not as complete as they are today, their spirit of exploration really admired us. Although the naming at that time may not be as accurate as it is now, it still follows certain rules.
Today's 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene is widely used in various fields of chemical industry. Its synonymous name and trade name are the key to communication in the industry. Only by accurately mastering can we communicate in research and production, and promote the vigorous development of the chemical industry.
Safety & Operational Standards
2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene Safety and Operating Specifications
F 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene, chemical products are also. Its characteristics are different, related to safety and operating standards, and should not be careless.
#1. Storage Rules
This product should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Its container must be tightly sealed to avoid contact with air and moisture, due to the risk of deterioration. And should not be stored in one place with oxidants, strong alkalis, etc., for fear of violent reactions, endangering safety.
#Second, the operation
When handling this object, you must wear appropriate protective clothing, such as laboratory clothes and protective gloves, to avoid contact with the skin. The face also needs protection, wearing protective glasses to prevent liquid from splashing into the eyes. In the operation room, ventilation equipment must be good, so that the volatile gas can be quickly dissipated, so as to avoid excessive concentration in the air.
When weighing, the action should be gentle and precise to avoid the powder flying. When dissolving or mixing, when adding slowly according to the procedure, and constantly stirring, so that the reaction is smooth. The heating operation needs to be especially careful, control the temperature and rate, and do not raise the temperature suddenly to prevent the risk of flushing or explosion.
#3. Emergency measures
If you accidentally touch the skin, quickly rinse with plenty of water, and then wash with soap. If it enters the eye, immediately open the eyelids, rinse with flowing water or normal saline, and then seek medical attention. In case of fire, use dry powder fire extinguishers, carbon dioxide fire extinguishers to fight, do not use water, because it is insoluble in water, water will help the fire spread.
All of these are the safety and operation norms of 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene. Practitioners should keep in mind and follow them in order to ensure the smooth experiment and personnel safety.
Application Area
2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene is also an organic compound. Its application field is quite extensive. In the field of medicinal chemistry, or as a key intermediate in the synthesis of specific drugs, with its unique chemical structure, it can derive many molecules with specific pharmacological activities, helping to overcome difficult diseases. In the field of materials science, it can be integrated into the structure of new materials through specific reactions, endowing materials with special optical and electrical properties, expanding the application boundaries of materials. Or in the fine chemical industry, it is an important raw material for the preparation of high-end fine chemicals, improving product quality and performance. With its diverse chemical properties, this compound shows great application potential in various fields and promotes scientific and technological development and innovation in various fields.
Research & Development
In recent years, I have dedicated myself to the research of 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene. This material is special and has great potential in the field of organic synthesis.
Initially, I studied the preparation method of this compound. After several attempts, a path was obtained, and it was obtained in an optimum yield. During this period, the choice of raw materials and the reaction strip were carefully considered. Temperature, duration, and amount of catalyst are all key.
Then, its reactivity was explored. In contact with various reagents, it reacts in a variety of ways, and various derivatives can be derived. This property paves the way for the creation of new compounds.
Looking forward to the future, we hope to use this as a basis to explore new applications. Or in the genus of medicine and materials, develop their talents. Unremitting research, with the aim of advancing chemistry, contribute my strength, and promote this compound to shine in various fields, so as to make more innovations and breakthroughs.
Toxicity Research
Toxicity of this chemical 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene. This product contains bromine, fluorine and other elements, and its structure may cause unique toxicity. Although the relevant toxicities are not widely recorded at present, they may be potentially harmful from the perspective of similar halogenated aromatic hydrocarbons. The atomic properties of bromine and fluorine may affect their metabolism and reaction in organisms.
After consideration, it may disturb the cell structure and function of organisms. If it enters the body, or interacts with biological macromolecules such as proteins and nucleic acids, it will cause disorders in physiological processes. And halogenated aromatics are mostly lipid-soluble, easy to store in adipose tissue, and can accumulate toxic effects for a long time. Although the current research does not fully understand its toxicity, it should not be ignored. When studied rigorously, the exact toxicity mechanism and degree of harm should be investigated to provide a solid basis for protection and application.
Future Prospects
2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene is the key to our dedicated research. Its future development is quite impressive. This substance has potential for great use in various fields of chemical industry. We want to use profound methods to explore more of its mysteries.
Looking at past research, although it has been achieved, the future is still far away. We hope to use new technologies and new ideas to dig deep into its properties, so that it can add wings to industry, and also shine in pharmaceutical research and development. It may be possible to improve the process, reduce costs and increase efficiency, and make its production smoother. And hope that it can become a mainstay in material innovation, paving the way for future development. We should work tirelessly to achieve this unfinished vision, so that the potential of 2 - Bromo - 5 - Fluoro - 1,3 - Dimethylbenzene will fully bloom in the future.
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Frequently Asked Questions

As a leading 2-Bromo-5-Fluoro-1,3-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-5-Fluoro-1,3-Dimethylbenzene?
2-Bromo-5-fluoro-1,3-dimethylbenzene, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
In the field of medicinal chemistry, with its unique structure, it can participate in the construction of many drug molecules. Because of its specific substituents, it can endow the synthesized drug with specific activities and properties. For example, through carefully designed reactions, it can be converted into compounds with specific pharmacological activities, which may be used to develop drugs for the treatment of certain diseases.
It is also of great value in materials science. With its chemical structure characteristics, it can become a starting material for the synthesis of materials with special properties. Through a series of organic reactions, it is polymerized or modified with other compounds to produce materials with unique electrical, optical or mechanical properties, such as in the field of organic optoelectronic materials, which may play a key role.
In the field of pesticide chemistry, it may also show unique uses. It can be used as an important intermediate in the synthesis of new pesticides to prepare pesticide products with efficient control effects on specific pests or diseases, providing strong support for pest control in agricultural production.
This compound has potential application value in many fields due to its unique molecular structure, and is an indispensable and important substance in the research of organic synthetic chemistry and the development of related industries.
What are the physical properties of 2-Bromo-5-Fluoro-1,3-Dimethylbenzene?
2-Bromo-5-fluoro-1,3-dimethylbenzene is one of the organic compounds. Its physical properties are particularly important and are related to many practical applications.
First of all, its appearance is usually colorless to light yellow liquid, clear and transparent, and it looks quite fluid. This appearance characteristic is quite critical for visual identification and preliminary determination.
As for the boiling point, it is about a specific temperature range. This value is roughly within a certain range due to specific measurement conditions or slight differences. The characteristics of the boiling point are of great significance in the separation and purification of this compound. The method of distillation can be used to separate the mixture according to the difference in boiling points to obtain pure 2-bromo-5-fluoro-1,3-dimethylbenzene.
Melting point is also an important physical property. Its melting point is near a certain temperature point. Below this temperature, the compound is in a solid state, and above it is a liquid state. The accurate determination of the melting point can help to identify the purity of the compound. If impurities are mixed, the melting point is often abnormal.
In terms of density, this compound has a specific density value, which is measured by the mass per unit volume. This density characteristic is a key consideration in the process of mixing and phase separation of substances. According to the density difference, effective separation and analysis of substances can be achieved.
The solubility cannot be ignored. 2-Bromo-5-fluoro-1,3-dimethylbenzene has a certain solubility in organic solvents, such as common ethanol, ether, etc., but it has little solubility in water. This solubility characteristic is an important basis for selecting suitable solvents in chemical synthesis, extraction and other operations.
Furthermore, its volatility is also an important characteristic. Under normal temperature and pressure, it has a certain volatility. This characteristic affects its storage and use environment. It needs to be properly sealed and stored to prevent volatilization loss, and used in a well-ventilated place for safety.
In summary, the physical properties of 2-bromo-5-fluoro-1,3-dimethyl benzene, such as appearance, boiling point, melting point, density, solubility and volatility, play a crucial role in its research, production and application in the field of chemistry.
What are the chemical properties of 2-Bromo-5-Fluoro-1,3-Dimethylbenzene?
2-Bromo-5-fluoro-1,3-dimethylbenzene is one of the organic compounds. Its chemical properties are unique and diverse.
From the perspective of the properties of halogenated aromatics, the bromine atom in this compound is quite active. In the nucleophilic substitution reaction, the bromine atom is easily replaced by the nucleophilic reagent. Because the bromine atom is a good leaving group, when attacked by the nucleophilic reagent, the carbon-bromine bond is easily broken, and then a new carbon-nucleophilic bond is formed. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed; when reacted with ammonia or amine, nitrogen-containing derivatives can be obtained.
The presence of fluorine atoms also affects the chemical properties of this compound. The fluorine atom is extremely electronegative, which will absorb electrons and reduce the electron cloud density of the benzene ring. This electronic effect not only affects the activity of electrophilic substitution on the benzene ring, but also has a significant impact on the electron cloud distribution of ortho and para-sites. In the electrophilic substitution reaction, compared with similar aromatic hydrocarbons without fluorine atoms, the reactivity may change, and the attack position of the electrophilic reagent is also controlled by the localization effect of the fluorine atom. The presence of two methyl groups in the
molecule, as the power supply radical, will increase the electron cloud density of the benzene ring and activate the electrophilic substitution reaction. The presence of methyl groups changes the charge distribution of the benzene ring, making the ortho and para- Under suitable conditions, this compound can undergo electrophilic substitution reactions such as nitrification, halogenation, and sulfonation, and methyl groups can guide the selection of reaction check points.
The chemical properties of this compound are complex, and the interaction between bromine atoms, fluorine atoms and methyl groups jointly determines its performance in various chemical reactions, which brings many possibilities and research values to the field of organic synthesis.
What are the synthesis methods of 2-Bromo-5-Fluoro-1,3-Dimethylbenzene?
To prepare 2-bromo-5-fluoro-1,3-dimethylbenzene, the following number method is often followed.
First, 1,3-dimethylbenzene is used as the starting material. Shilling it with fluorinated reagents, such as Selectfluor, etc., under the catalysis of appropriate temperature and catalysts such as Lewis acid (such as ferric chloride, etc.), electrophilic substitution is performed to obtain 5-fluoro-1,3-dimethylbenzene. In this step, the fluorine atom selects a site to replace a specific position on the benzene ring. Then, 5-fluoro-1,3-dimethylbenzene and bromine, in the presence of light or an initiator, such as benzoyl peroxide, or catalyzed by Lewis acid, are electrophilically substituted to replace the ortho-hydrogen of the bromine atom to obtain the target product 2-bromo-5-fluoro-1,3-dimethylbenzene.
Second, 2-methyl-5-nitrobenzene can also be used as the starting point. After fluoridation, the nitro group is fluorinated to obtain 2-methyl-5-nitro-1-fluorobenzene by a specific fluorinating reagent, such as potassium fluoride, in synergy with a phase transfer catalyst. Then, the nitro group is reduced to an amino group by a suitable reducing agent, such as iron and hydrochloric acid system or catalytic hydrogenation, to obtain 2-methyl-5-amino-1-fluorobenzene. Then through the diazotization reaction, the amino group is converted into a diazonium salt, and then interacts with reagents such as cuprous bromide. The diazonium group is replaced by a bromine atom. At the same time, the methylation reagent, such as iodomethane, interacts with a base (such as potassium carbonate) to achieve methylation, and finally obtains 2-bromo-5-fluoro-1,3-dimethylbenzene.
These two types of methods have their own advantages and disadvantages. The first step is slightly simpler, but the reaction conditions may need to be precisely regulated. Although the second method is complicated, some of the reaction selectivity is good, which can be selected according to actual needs and conditions.
2-Bromo-5-Fluoro-1,3-Dimethylbenzene What are the precautions in storage and transportation?
For 2-bromo-5-fluoro-1,3-dimethylbenzene, many precautions must be paid attention to during storage and transportation.
This chemical substance has certain chemical activity and potential hazards. When storing, choose the first environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Cover because it is exposed to open flames, hot topics or the risk of combustion and explosion.
Furthermore, it needs to be stored separately from oxidants, acids, alkalis and other substances, and must not be mixed. Because of its chemical properties, or violent reactions with their substances, it is dangerous to safety. In the warehouse, there should be suitable equipment for containing and handling leaks, in case of leakage, it can be properly disposed of in a timely manner.
During transportation, do not slack off. Packaging must be tight to ensure that no leakage occurs during transportation. Transportation vehicles need to be equipped with corresponding types and quantities of fire equipment and leakage emergency treatment equipment. During driving, it is necessary to protect against sun exposure, rain and high temperature. During transportation, the route should be driven according to regulations, and do not stop in residential areas and densely populated areas. Escort personnel should also be familiar with the nature of the goods transported and emergency treatment methods, and guard carefully along the way.
Therefore, when storing and transporting 2-bromo-5-fluoro-1,3-dimethylbenzene, adhere to all precautions to ensure safety and avoid accidents.