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2-Bromo-5-Chloro-1,3-Difluorobenzene

2-Bromo-5-Chloro-1,3-Difluorobenzene

Hongda Chemical

Specifications

HS Code

717614

Chemical Formula C6H2BrClF2
Molecular Weight 229.43
Appearance Liquid (usually)
Boiling Point Data may vary, around 180 - 200 °C (approximate)
Melting Point Data may vary
Density Data may vary
Solubility Insoluble in water, soluble in organic solvents like dichloromethane
Vapor Pressure Low vapor pressure
Flash Point Data may vary
Stability Stable under normal conditions but reacts with strong oxidizing agents

As an accredited 2-Bromo-5-Chloro-1,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - bromo - 5 - chloro - 1,3 - difluorobenzene in a sealed, labeled bottle.
Storage 2 - bromo - 5 - chloro - 1,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions.
Shipping 2 - bromo - 5 - chloro - 1,3 - difluorobenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling, handling, and transport to prevent spills and environmental exposure.
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2-Bromo-5-Chloro-1,3-Difluorobenzene 2-Bromo-5-Chloro-1,3-Difluorobenzene
General Information
Historical Development
2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene, also an organic compound. The history of its development, at the beginning, chemists devoted themselves to the research and development of organic halides. At that time, it was difficult to explore the synthesis of such aromatic hydrocarbons containing polyhalides.
People have tried repeatedly in terms of reaction conditions and raw material selection. After a long time, there has been a breakthrough. Chemists have gradually been able to effectively prepare this substance with the help of new catalysts and unique reaction paths. When it was first obtained, the yield was still low and the quality was not sufficient. However, with unremitting research, the process has been perfected day by day, the yield has been improved, and the product purity has also been guaranteed. Therefore, 2-Bromo-5-Chloro-1,3-Difluorobenzene has gradually gained an important position in the field of organic synthesis, laying the foundation for many subsequent studies and applications.
Product Overview
2-Bromo-5-chloro-1,3-difluorobenzene
The name of 2-bromo-5-chloro-1,3-difluorobenzene is a genus of organic compounds. Its shape is colorless to light yellow liquid with a special odor. The molecular structure is exquisite, and bromine, chlorine and fluorine atoms are cleverly arranged on the benzene ring, giving this compound unique chemical properties.
In the field of organic synthesis, this compound has a wide range of uses. Due to its halogen atom activity, it can be used as a key intermediate and participate in many organic reactions. Through reaction pathways such as nucleophilic substitution, various functional groups can be introduced, laying the foundation for the preparation of complex organic molecules.
Furthermore, its physical and chemical properties are stable, and it can maintain its own structure and properties under specific conditions. However, it should also be noted that halogenated aromatics may have certain toxicity and environmental effects. Therefore, during their preparation and use, they should follow the specifications and be properly handled to ensure safety and environmental friendliness.
Physical & Chemical Properties
2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene is an organic compound. Its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific boiling point and melting point. The boiling point is related to the temperature of its gasification, and the melting point is the node of its solid-state to liquid state. Its density is also one of its characteristics, which is related to the compactness of the substance.
On its chemical properties, due to the presence of benzene rings, it has aromatic properties and can participate in electrophilic substitution reactions. The presence of bromine, chlorine and fluorine atoms gives it unique reactivity. Bromine and chlorine atoms can undergo substitution reactions under appropriate conditions. Fluorine atoms have strong electronegativity, which affects the electron cloud distribution of molecules and makes their chemical properties different from others. The properties of this compound are widely used in organic synthesis and other fields, helping researchers to create a variety of new compounds.
Technical Specifications & Labeling
Today there is a product called 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene. The technique of its production is related to the delicacy of chemistry. If you want to understand its technical specifications and identification (product parameters), you should check it carefully.
To make this product, you need to follow a precise method. From the selection of raw materials to the control of the reaction, there are rules. The raw materials must be pure, and the temperature, time and amount of the reaction are all key. According to this standard, you can get its high-quality products.
In terms of labeling, remember the product parameters in detail. Such as the proportion of ingredients, the geometry of this 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene, and the geometry of impurities must be clearly marked. And its physical properties, color, taste, state, etc., cannot be omitted. In this way, the user can make it clear so that it can be applied to various scenarios. Following this technical specification and labeling method is the right way to manufacture this product.
Preparation Method
The method of making 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, and the quality of the carefully selected pure product should be carefully selected to ensure a smooth reaction. In the production process, the temperature and pressure conditions must be strictly controlled. The reaction steps are gradual, the first step... the second step... In the catalytic mechanism, the suitable catalyst is selected to promote the reaction to be efficient. In this way, after delicate deployment and operation, this excellent product can be prepared to obtain the required 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene, and the quality is excellent, suitable for various purposes.
Chemical Reactions & Modifications
Taste the industry of chemical industry, and explore the way of material change. Today there is a thing called "2-Bromo-5-Chloro-1,3-Difluorobenzene", and its chemical reaction and modification are quite valuable to study.
To investigate its reaction, when its structure is known. In this compound, bromine, chlorine, and fluorine atoms, according to their positions, affect the activity of molecules. In common reactions, such as nucleophilic substitution, halogen atoms can be used as leaving groups, but due to the strong electronegativity of fluorine, the reaction conditions are different.
Talking about modification, specific functional groups can be introduced to change its properties. Or increase its stability, or change its solubility. Such as attacking with nucleophilic reagents, introducing hydroxyl groups, amino groups, etc., to form new substances and have different functions. Chemical researchers should study this carefully to achieve a wonderful environment and contribute to the progress of the chemical industry.
Synonyms & Product Names
Today there is a thing called 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene. Although its name is different from the common saying, it is also an important product in the field of my chemistry. The aliases of this thing also have various names. Its chemical name depends on its structural composition, accurately describing the combination and arrangement of its atoms.
The name of the commodity passed down in the market varies depending on the way it is used and the method of making it. However, no matter what the name is, it refers to the same thing. It is indispensable in chemical research and industrial production. Researching its properties and studying its application can open up new paths and open up new opportunities in many fields. Although the names are different, their essence is the same, and they are known and studied by my generation of chemistry students and practitioners.
Safety & Operational Standards
2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene Safety and Operation Specifications
F 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene, a compound commonly used in chemical research. Its safety and operation specifications cannot be ignored.
When storing, it must be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Because of its certain chemical activity, heat may cause reactions and cause dangerous life. And should be stored separately from oxidants, acids, bases, etc., must not be mixed with storage to avoid interaction and cause harm.
When operating, it is necessary to strictly follow the specifications. Operators must wear appropriate protective equipment, such as protective glasses, gloves and protective clothing, to protect their own safety. Because the compound may be irritating to the skin and eyes, or even may cause damage.
During the retrieval process, the action should be slow and steady, and beware of spilling. If it is accidentally spilled, take appropriate measures immediately. Small leaks can be absorbed by inert materials such as sand and vermiculite, and collected in a suitable container for proper disposal. If there are large leaks, the surrounding personnel should be evacuated quickly, and a warning area should be demarcated and handled by professionals.
The experimental site should be equipped with good ventilation equipment to disperse possible volatile gases and reduce the concentration of the compound in the air to avoid the risk of poisoning. And before and after operation, the equipment should be carefully checked to ensure that it is in normal operation and does not leak.
Furthermore, after use, the remaining 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene should not be discarded at will, and should be properly disposed of according to the prescribed procedures to prevent pollution to the environment.
In general, in the research and use of 2 - Bromo - 5 - Chloro - 1, 3 - Difluorobenzene, safety and operating standards are of paramount importance. Strict adherence to this regulation can ensure the smooth operation of the research, the safety of personnel, and the harmlessness of the environment.
Application Area
2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene is a unique compound. In today's various application fields, its extraordinary ability has been revealed.
Looking at the field of pharmaceutical research and development, this compound may be a key raw material for the creation of new specific drugs. Due to the special arrangement and properties of halogen atoms, it may endow drugs with precise targeting, making drugs more effective in the human body to act on specific lesions and help doctors overcome many intractable diseases.
In the field of materials science, 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene may participate in the synthesis of materials with unique properties. Its structural characteristics may optimize the stability, conductivity or optical properties of materials, opening up new possibilities for fields such as electronic devices and optical materials, and pushing science and technology to new heights.
Research & Development
Recently, it has been a lot of effort to study 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene. The preparation method needs to be carefully studied. The selection of raw materials is related to the purity of the product, the reaction conditions, such as temperature, pressure, and the amount of catalyst, all of which must be precisely controlled.
I study ancient books day and night, refer to the methods of various families, and try repeatedly to improve the process. This substance has potential applications in many fields, such as medicine and materials. If its preparation process can be optimized, and the yield and purity can be improved, it will definitely promote the development of related industries.
Although the road ahead is long and difficult, I am committed to research and development. Every attempt is a step closer to the truth, hoping to make an early breakthrough and make a modest contribution to academia and industry.
Toxicity Research
The nature of taste and smell is related to human use, and the study of toxicity is particularly important. Today there is a substance called "2-Bromo-5-Chloro-1,3-Difluorobenzene", and the investigation of its toxicity cannot be ignored.
To study the toxicity of this substance, many aspects need to be considered. The path of its entry into the body, or by breathing, or by contact, can be observed. And observe its response in the living body, whether there are any abnormalities, such as physiological changes and damage to function. And the effect of long-term exposure to understand the potential danger.
Furthermore, the diffusion and transformation of this substance in the environment must also be investigated. Its impact on the surrounding organisms, from microalgae to birds and beasts, cannot be ignored. In this way, a detailed study of the toxicity of "2-Bromo-5-Chloro-1,3-Difluorobenzene" can provide good evidence for safety and ecological stability, so as to avoid disasters.
Future Prospects
I have dedicated myself to the research of this 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene. Looking at the present, it has emerged in various fields and its application is gradually widening.
However, what I hope for in the future is the improvement of synthesis. Hope to find better ways to reduce steps, yield, energy consumption, and make preparation easier and more efficient. Next, expand its application. In medicinal chemistry, it may become a key intermediate to assist in the development of new drugs and cure various diseases; in materials science, it may be able to introduce new materials, such as excellent electrical conductivity and optical properties, to meet diverse needs.
Furthermore, environmental protection is also the key. The research and development process should focus on green chemistry, avoid harmful reagents, control waste, and make production and the environment coexist in harmony. In this way, 2 - Bromo - 5 - Chloro - 1,3 - Difluorobenzene will surely shine in the future, be used by the world and benefit all people.
Where to Buy 2-Bromo-5-Chloro-1,3-Difluorobenzene in China?
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Frequently Asked Questions

As a leading 2-Bromo-5-Chloro-1,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-5-Chloro-1,3-Difluorobenzene?
2-Bromo-5-chloro-1,3-difluorobenzene is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. It can be carefully converted into drug molecules with unique structures through specific reaction steps, helping to create new drugs for the treatment of various diseases.
In the field of pesticide chemistry, this compound also plays an important role. It can be used as a starting material to prepare pesticide products with high insecticidal and bactericidal properties through a series of exquisite synthesis steps, providing a powerful means for agricultural pest control.
Furthermore, in the field of materials science, 2-bromo-5-chloro-1,3-difluorobenzene can participate in the synthesis of functional materials with special properties. For example, by polymerizing with other specific monomers, polymer materials with unique electrical, optical or thermal properties are generated to meet the needs of special materials in different fields.
From this perspective, although 2-bromo-5-chloro-1,3-difluorobenzene is an organic compound, it has shown important uses in many fields such as medicine, pesticides, and materials, and is of great significance to promote the development of related fields.
What are the physical properties of 2-Bromo-5-Chloro-1,3-Difluorobenzene?
2-Bromo-5-chloro-1,3-difluorobenzene is one of the organic compounds. Its physical properties are quite important, and it is related to many chemical processes and applications.
First of all, its appearance, at room temperature, is mostly colorless to light yellow liquid, with a clear texture and a flowing state. This appearance feature is crucial for visually distinguishing this substance.
The boiling point is about a specific temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gaseous state. The boiling point of 2-bromo-5-chloro-1,3-difluorobenzene allows it to undergo a phase change in the corresponding temperature environment. If the ambient temperature rises to the boiling point, the liquid gradually turns into a gas.
Melting point is also an important physical property. The melting point of this substance is at a certain value. Below this temperature, the substance exists in a solid state. The characteristics of the melting point affect its physical form under different temperature conditions.
The density cannot be ignored either, and its density is a constant value. For density, the mass of the substance per unit volume is also. This value reflects the compactness between the molecules of the compound and the way of packing. Through density, the quality of the space occupied by it under specific conditions can be known.
In terms of solubility, 2-bromo-5-chloro-1,3-difluorobenzene has a certain solubility in organic solvents. For example, common organic solvents such as ethanol and ether can interact with them to disperse the compound. However, the solubility in water is poor. Due to the characteristics of molecular structure, the force between water molecules and water molecules is weak, making it difficult to form a uniform dispersion system.
In addition, its volatility also has characteristics. At room temperature and pressure, there is a certain volatility, that is, the molecule has a tendency to escape from the liquid surface to the gas phase. This volatility affects its diffusion and stability in the environment.
The above physical properties are of great significance in chemical synthesis, separation and purification, storage and transportation, etc., providing a key basis for research and practice in related fields.
What are the synthesis methods of 2-Bromo-5-Chloro-1,3-Difluorobenzene?
The synthesis method of 2-bromo-5-chloro-1,3-difluorobenzene covers a variety of paths.
First, it can be started from a suitable aromatic compound. If benzene is used as the original substrate, chlorine atoms and fluorine atoms are first introduced through a halogenation reaction. Under specific reaction conditions, a chlorinated reagent is used to react with benzene, so that chlorine atoms are selectively introduced into the appropriate position of the benzene ring, and then a fluorinated reagent is used to carry out a fluorination reaction, so that the fluorine atoms are connected to the designated part of the benzene ring. Then, the bromine atoms are treated with a brominated reagent to enter the predetermined position, thereby obtaining the target product 2-bromo-5-chloro-1,3-difluorobenz This path requires fine regulation of reaction conditions and reagent ratios to achieve selectivity and yield of each step of the reaction.
Second, it can also start from aromatic compounds with partial substituents. If fluorine and chlorine-containing benzene derivatives are used as raw materials, bromine atoms are introduced into the appropriate position through appropriate reaction strategies. For example, by means of nucleophilic substitution reactions, bromine-containing nucleophiles react with substrates under suitable basic conditions and solvents to achieve the introduction of bromine atoms. In this process, the influence of substrate structure on reaction activity and selectivity needs to be considered, and the reaction parameters can be carefully optimized to ensure the formation of target products.
Third, the use of transition metal catalysis is also an important approach. Transition metals such as palladium are used as catalysts with specific ligands to promote cross-coupling reactions between halogenated aromatics. For example, halogenated benzene derivatives containing chlorine and fluorine and halogenated aromatics containing bromine are cross-coupled under palladium catalysis in a suitable reaction environment to construct the molecular structure of 2-bromo-5-chloro-1,3-difluorobenzene. This method requires precise selection of catalysts, ligands and reaction conditions to improve reaction efficiency and selectivity.
There are many methods for the synthesis of 2-bromo-5-chloro-1,3-difluorobenzene, each method has its own advantages and disadvantages. It is necessary to weigh the selection according to the actual needs and conditions, and fine optimization can be used to prepare this compound efficiently.
What are the precautions for storing and transporting 2-Bromo-5-Chloro-1,3-Difluorobenzene?
2-Bromo-5-chloro-1,3-difluorobenzene is an organic compound. During storage and transportation, many key matters must be paid attention to so that security is safe.
The first word for storage is that because of its chemical activity, it should be stored in a cool, dry and well-ventilated place. This compound is prone to reaction in case of heat, or even the risk of decomposition, so it must be kept away from heat sources and fires, such as heating, open flames, etc. The temperature of the warehouse should be controlled within a certain range, and it must not be too high. Humid gas will also affect its stability, so the ambient humidity should also be properly controlled.
Furthermore, this compound should be stored separately from substances such as oxidizing agents, reducing agents and alkalis. Due to its active chemical properties, contact with these substances is very likely to cause violent chemical reactions, which can even lead to serious accidents such as fire and explosion. In the storage area, clear signs should be set up to indicate what is stored and its danger, so that personnel can identify and prevent it. At the same time, regular inspections of storage equipment and the environment should be carried out to check for abnormal conditions such as leakage.
As for transportation, it should not be taken lightly. Before transportation, it is necessary to ensure that the packaging is intact. Packaging materials must be able to effectively resist vibration, collision and friction to prevent material leakage caused by container rupture. Transportation vehicles should be equipped with corresponding fire equipment and emergency treatment equipment for emergencies. During transportation, the driving route should be carefully planned to avoid densely populated areas and environmentally sensitive areas in case of accidents that affect many people.
The escort personnel must undergo professional training and be familiar with the characteristics of this compound and emergency treatment methods. During transportation, pay close attention to the status of the goods. If any signs of damage or leakage in the packaging are found, effective measures should be taken immediately, such as plugging and transferring materials, and timely report to the relevant departments. In short, whether it is storing or transporting 2-bromo-5-chloro-1,3-difluorobenzene, safety regulations must be strictly followed to ensure the safety of personnel and the environment.
What are the effects of 2-Bromo-5-Chloro-1,3-Difluorobenzene on the environment and human health?
2-Bromo-5-chloro-1,3-difluorobenzene is a genus of organic compounds. Its impact on the environment and human health is detailed as follows.
At the environmental end, this compound is quite stable and difficult to decompose rapidly in the natural environment. If it is released into the soil or retained in the soil particles due to adsorption, it may affect the structure and function of the soil microbial community, hindering the material cycle and energy conversion of the soil ecosystem. Once infiltrated into water bodies, due to its hydrophobicity, it may accumulate in aquatic organisms, pass through the food chain, amplify, and threaten the survival and reproduction of aquatic organisms. For example, if the concentration of this compound in water increases, or the growth of plankton is inhibited, and then the entire aquatic food chain is impacted, such as the reduction of small fish due to food shortage, and the large fish are also trapped. And if it evaporates in the atmosphere, or reacts chemically with other substances in the atmosphere, it affects the chemical composition of the atmosphere. However, due to limited volatility, the content in the atmosphere may not be too high.
As for human health, it may enter the human body through respiratory tract, skin contact and accidental ingestion. In the body, it may interfere with normal physiological and biochemical processes. The halogen atoms of this compound are active, or react with biological macromolecules such as proteins and nucleic acids in the body, causing abnormal protein structure and function, affecting normal cell metabolism and signal transduction. Nucleic acid damage may cause gene mutations, long-term accumulation, and a sharp increase in the risk of carcinogenesis. Studies have also shown that such halogenated aromatic compounds may interfere with the human endocrine system, affect the synthesis, secretion and function of hormones, cause endocrine disorders, and cause a series of health problems, such as reproductive dysfunction and developmental abnormalities. And exposure to high concentrations of this substance may have irritating effects on the skin, eyes, etc., causing redness, swelling, pain and other uncomfortable symptoms.
In short, 2-bromo-5-chloro-1,3-difluorobenzene poses latent risks to the environment and personal health. During production, use and disposal, proper prevention and control are required to reduce its adverse effects.