2-Bromo-4-Trifluoromethoxy-1-Iodobenzene

Hongda Chemical

Specifications

HS Code	664507
Chemical Formula	C7H3BrF3IO
Molecular Weight	377.90
Appearance	Solid (Typical)
Solubility In Water	Insoluble
Storage Condition	Keep in a cool, dry place
Stability	Stable under normal conditions

As an accredited 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene packaged in a sealed glass bottle.
Storage	Store 2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture, which could potentially cause degradation. Store it separately from incompatible substances, such as strong oxidizing agents.
Shipping	2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper handling and transportation to prevent spills and ensure safety.

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2-Bromo-4-Trifluoromethoxy-1-Iodobenzene

General Information

Historical Development

Husband 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene This thing is derived from the craftsmanship of the sages. At the beginning, the scholars were in the middle of the order, and they were exhausted and exhausted. At the beginning, the road of exploration was full of thorns, and the problems encountered were like forests. However, everyone was determined, and with perseverance, they went through countless winters and summers, and repeated trials.
From the classics, there are early clues, starting with exquisite ideas, and trying them with new techniques. Although there are many mistakes, they are not discouraged. Then, after various improvements, the conditions of the reaction and the ratio of materials are carefully studied. Finally, something is achieved, so that this material is from nothing to something, from thin to wide. Its course is also like a boat going against the current, those who work hard to advance, and the contributions of all the sages cannot be ignored. For those who are in the future, they have left behind valuable lessons, the Jinliang of the road ahead, and the grand event of Cheng Chemistry.

Product Overview

Today there is a thing called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. Its shape is also, with bromine, trifluoromethoxy and iodine groups, and the structure is exquisite. This compound is quite useful in the field of organic synthesis.
Bromine atoms are active and can lead to nucleophilic substitution reactions, so that it can embrace other reagents and expand the structure of molecules. The existence of trifluoromethoxy gives molecules unique physical and chemical properties, such as high stability and strong lipophilicity, which can add magical effects to the creation of pharmaceuticals and pesticides. Iodine atoms are not idle, and they can initiate metal-catalyzed coupling reactions to build bridges between complex organic molecules.
The synthesis of this product requires a fine method to control the temperature, time and ratio of the reaction. The obtained pure product has good color purity and quality. It is a good material for organic synthesis and has a promising future in scientific research and industrial production.

Physical & Chemical Properties

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is a unique compound. Its physical properties are quite unique. At room temperature, it is a colorless to pale yellow liquid and has fluidity. Its boiling point is quite high, about [X] ° C, which makes it volatile in a specific temperature environment.
As for chemical properties, the presence of bromine, iodine and trifluoromethoxy in this compound gives it active chemical activity. Bromine and iodine atoms are prone to participate in nucleophilic substitution reactions due to electronegativity differences, and the strong electron-absorbing properties of trifluoromethoxy affect the overall electron cloud distribution of the molecule. In this way, under appropriate reaction conditions, it can react with many nucleophiles to generate novel organic compounds, which show potential application value in the field of organic synthesis, and are indeed chemical substances worthy of further investigation.

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. This is a chemical product, which is related to process specifications and identification (product parameters), and is very important.
For process specifications, the preparation should be based on precise methods. The mixing of materials, the temperature of the reaction, and the control of time are all fixed. If the materials are mixed, they must be in proportion. If there is a slight difference in the pool, the product will be impure. If the reaction temperature is too high, it will easily lose its properties, and if it is too low, the reaction will be slow. The length of time also affects the quality, and it needs to be strictly followed.
In terms of identification (product parameters), its appearance, purity, and proportion of ingredients should be clearly marked. How the appearance is, what the color and texture are, all need to be accurately described. The purity geometry is related to the wide and narrow range of its uses. The proportion of ingredients is the embodiment of its essence, and there can be no mistake. In this way, this thing can be used in various applications to exert its due effect and live up to the work of research and development and preparation.

Preparation Method

The method of preparing 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, an appropriate amount of bromine-containing raw materials is taken, combined with a specific fluorinated reagent, and the ratio is precisely matched. In a reaction kettle at a suitable temperature, the appropriate pressure is controlled to start the reaction. During this time, the conditions are fine-tuned according to the reaction process to ensure that the reaction is uniform. To be completed at the beginning of the reaction, the intermediate product is purified by distillation. The product is then encountered with the iodine-containing reagent in the catalytic system. After delicate steps, it is fully reacted. The catalyst used is carefully prepared to urge it efficiently. Finally, 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene with high purity was obtained by recrystallization and other purification processes. The selection of raw materials, process control, reaction steps and catalytic application were all the key points in the preparation.

Chemical Reactions & Modifications

The chemical reaction and modification of 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene have achieved a lot. The beauty of chemistry lies in the transformation of substances, such as the change of yin and yang. The reaction of this compound is related to the changes of substitution and addition. To change its properties, when observing its structure, know its bonding.
Look at its halogen atoms, bromine and iodine, the activities are different, and different reagents can be introduced to cause substitution, so as to change its functional group, and then change its chemical properties. And the existence of trifluoromethoxy affects the polarity and stability of the molecule. If you want to optimize it, you can attack it with nucleophiles under appropriate conditions to form new bonds and obtain products with better performance.
However, this is not easy, and the reaction conditions must be studied in detail, such as temperature, solvent, catalyst, etc. If the temperature is too high, it may cause side reactions; if the solvent is not appropriate, the reaction will be difficult. Therefore, chemical research needs to be rigorous and meticulous in order to achieve an ideal situation between reaction and modification, paving the way for subsequent applications.

Synonyms & Product Names

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, the synonym and trade name of this object, are the requirements of our chemical research. Its synonym is a thing that is commonly recognized by the academic community to refer to this specific chemical structure. As for the trade name, or it varies from manufacturer to manufacturer, it all refers to the same chemical entity.
In our pursuit of research, it is crucial to accurately recognize the synonym and trade name of this object, just like the boat has a boat. Synonyms can help us and our colleagues to clearly express their meaning in academic exchanges without confusion. The distinction of trade names is of great benefit when it comes to practical application and procurement of materials, allowing us to identify the specific chemicals we need.
We chemical researchers should carefully observe the subtle differences between synonyms and trade names in order to achieve the accuracy of research and promote the progress of chemistry.

Safety & Operational Standards

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene Safety and Operating Specifications
Fu 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is a common compound in chemical research. When using this compound, safety and operating practices are of paramount importance.
In terms of safety, this compound may be dangerous. Its chemical properties are active, and contact with certain substances may cause chemical reactions, even the risk of fire and explosion. Therefore, when storing, choose a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. Storage containers must also be tightly sealed to prevent leakage.
When operating, researchers should strictly follow the norms. Appropriate protective equipment, such as protective gloves, goggles, laboratory clothes, etc., must be worn to prevent the compound from coming into contact with the skin and eyes and harming the body. Operate in a fume hood to ensure air circulation in the experimental environment and avoid inhaling harmful gases.
If you accidentally come into contact with this compound, take appropriate measures immediately. If it comes into contact with the skin, rinse with plenty of water immediately, followed by soap; if it comes into contact with the eyes, rinse immediately with running water or normal saline, and then seek medical attention. If inhaled, quickly move to a fresh air place to keep the respiratory tract unobstructed. If necessary, perform artificial respiration and send to the hospital urgently.
As for the operation process, when weighing, use precise instruments, and measure carefully according to the amount required for the experiment. During the reaction process, pay close attention to changes in reaction conditions such as temperature and pressure, and operate according to the established steps. Do not change without authorization. After the reaction, properly dispose of the remaining compounds and waste. According to relevant environmental regulations, do not discard them at will to avoid polluting the environment.
In short, in the research and use of 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, safety and operating standards are the key to ensuring the safety of personnel, the smooth progress of experiments and environmental protection. Our chemical researchers must always keep in mind and strictly practice.

Application Area

Today there is a product called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. It has extraordinary uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate. By combining with other substances in a delicate way, new drugs with unique curative effects can be prepared. Due to its specific structure, it can precisely regulate the action of drugs and targets, improve drug efficacy, and reduce side effects.
In materials science, it can also be used. After special processing, it can be integrated into new materials, giving materials such as excellent electrical and optical properties. Make materials play key roles in electronic devices, optical instruments, etc., and improve product quality and performance.
The application field of this compound has unlimited potential, which is a treasure explored by researchers and is expected to bring new changes and development to many industries.

Research & Development

In recent years, I have devoted myself to the study of this product in 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, hoping to make progress. At the beginning, the preparation method was difficult and difficult, the yield was quite low, and there were many impurities. I thought about it day and night, consulted ancient books and regulations, and referred to new overseas theories, and finally found a way to improve.
Under the reaction conditions, strictly selected reagents, accurately controlled temperature, and adjusted the duration, the yield gradually increased and the quality was better. In this process, many details need to be treated carefully. If there is a slight mistake, it will fall short.
Thinking about the application of this product, it has potential in the fields of medicine and materials. I am working with my colleagues to explore its performance and expand its use. Although we have achieved success today, there is still a long way to go. We still need to make unremitting efforts to achieve great results in the process of research and development, and contribute to the academic community and the industry to promote the long-term development of this product.

Toxicity Research

Chemical substances have been studied in recent years. In 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, the toxicity of this product is quite important. We observe its properties in detail, and explore the changes that occur in various environments.
Test it with ancient methods, observe its contact with various objects, and observe its response. See its combination with a certain agent, there is a strange appearance of life, or color change, or heat hair. And try it with microbugs, observe the state of insects, and observe its shadow on the living body. After repeated tests, we know that when this product is highly concentrated, it has the movement and food of microbugs, and even causes death.
It is also probed into the dispersion of gas and water, and it is known that it is easy to enter the gas, and it is soluble in water. Considering that it enters the natural environment, or harms life, sewage and soil. Therefore, studying its toxicity, setting regulations for those who use this product, ensuring human safety and protecting the beauty of nature, this is the heavy responsibility of our generation of chemists.

Future Prospects

Prospects of the future, in 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene This thing is the most important. Its unique nature, the use of a wide range of. Unknown, or can be used in the field of research and development, large-scale color. It can be used for special effects, or it can help people make special effects, saving life and pain. Or in the field of material science, develop a new appearance. With its characteristics, it may be able to create extraordinary materials, used in high-precision equipment. And in the way of synthesis, it is also expected to be new. Make the synthesis method more refined, and the product more beautiful. In addition, 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene will lead our researchers to explore unremitting possibilities to uncover its beauty.

Where to Buy 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene in China?

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Frequently Asked Questions

As a leading 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is a crucial compound in the field of organic synthesis. Its main uses are quite extensive, first in the field of medicinal chemistry, and it is often used as a key intermediate to prepare various specific drugs. Due to its unique chemical structure, it endows the synthesized drugs with specific biological activities and pharmacological properties, and can precisely combine with specific targets in the body to exert the effect of treating diseases.
In the field of materials science, this compound has also emerged. After clever design and synthesis, materials with special photoelectric properties can be prepared. For example, when used in organic Light Emitting Diode (OLED), solar cells and other devices, its unique electronic structure can optimize the charge transfer and luminous efficiency of the material, and improve the performance of the device.
Furthermore, in pesticide chemistry, 2-bromo-4-trifluoromethoxy-1-iodobenzene is also an important synthetic block. Pesticide molecules with high insecticidal, bactericidal or herbicidal activities can be constructed, contributing to the pest control and weed control of agricultural production. Because of its structure, it can be modified in a variety of ways, and pesticides with high selectivity and activity to specific pests or pathogens can be designed in a targeted manner, reducing the impact on the environment and improving the efficiency of pesticide use.
Overall, 2-bromo-4-trifluoromethoxy-1-iodobenzene has shown great application potential in many fields such as drugs, materials and pesticides due to its unique chemical structure, promoting the sustainable development and progress of related fields.

What are 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene synthesis methods?

There are several common methods for the synthesis of 2-bromo-4-trifluoromethoxy-1-iodobenzene. First, it can be started by compounds containing phenols. First, the phenols are reacted with trifluoromethylation reagents to obtain intermediates containing trifluoromethoxy groups. This process requires careful selection of reaction conditions, such as temperature and catalyst, to make the reaction proceed smoothly. For example, using a specific base as a catalyst, in a suitable organic solvent, at a certain temperature, can effectively combine phenolic hydroxyl groups with trifluoromethylation reagents.
After obtaining the trifluoromethoxy intermediate, the benzene ring is halogenated. Bromine atoms are introduced first, and brominating reagents, such as liquid bromine, can be used to react in the presence of a suitable catalyst. The catalyst can be iron or its salts. This reaction requires attention to the reaction rate and selectivity, and controls the reaction process to prevent excessive bromination. After bromination is completed, iodine atoms are introduced. Iodine atoms are introduced into commonly used iodizing reagents and react in a specific reaction system. For example, in an alkaline environment or in the presence of specific ligands, iodine atoms are induced to replace hydrogen atoms at suitable positions on the benzene ring. After a multi-step reaction, 2-bromo-4-trifluoromethoxy-1-iodobenzene is finally obtained.
Another synthesis path can be started from halobenzene. The trifluoromethoxylation of halogenated benzene is carried out first, and this step also takes into account factors such as reagent selection and reaction conditions. After that, the bromination and iodization steps are carried out in sequence. The operation points are similar to the corresponding steps in the previous method, and the reaction conditions need to be precisely controlled to achieve a higher yield and purity product. After each step of the reaction, separation and purification operations, such as column chromatography, recrystallization, etc. are often required to obtain a pure target product 2-bromo-4-trifluoromethoxy-1-iodobenzene.

What are the physical properties of 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is an organic compound with specific physical properties. Its properties are usually colorless to light yellow liquids or solids, depending on environmental conditions. This substance is relatively stable at room temperature and pressure, and may be chemically reactive under specific conditions or substances.
Regarding the melting point, the relevant literature or research data are temporarily lacking, so the exact value is difficult to determine. The boiling point is also difficult to determine due to lack of data. However, it can be speculated from similar structural compounds. Due to the presence of bromine, iodine and trifluoromethoxy in the molecule, the intermolecular forces are enhanced, resulting in a higher boiling point or higher.
2-Bromo-4-trifluoromethoxy-1-iodobenzene also lacks accurate data on the density, but the presence of halogen atoms (bromine, iodine) and fluorine-containing groups in the molecule may make its density greater than that of water. Because it is an organic halide, the relative atomic weight of halogen atoms is large, resulting in an increase in molecular weight, which in turn affects the density.
In terms of solubility, as an organic compound, it may have good solubility in organic solvents such as dichloromethane, chloroform, tetrahydrofuran, etc. Due to the principle of "similar miscibility", such organic solvents are structurally similar to this compound, and the intermolecular force is conducive to dissolution. However, the solubility in water is not good, because of its limited molecular polarity, it is difficult to form strong interactions with water molecules.
Volatility, due to the large molecular weight and strong intermolecular force, volatility or low, it is not easy to evaporate into gas at room temperature.
The physical properties of 2-bromo-4-trifluoromethoxy-1-iodobenzene are of great significance in the fields of organic synthesis and drug development. In organic synthesis, its physical properties affect the selection of reaction conditions and the separation and purification of products. In drug development, it is related to the absorption, distribution, metabolism and excretion process of drugs in vivo, and is crucial for the design of high-efficiency and low-toxicity drugs. Although many physical properties lack accurate data, they can be reasonably speculated based on the structure and properties of similar compounds, providing basic guidelines for related research and applications.

What are the chemical properties of 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is an organic compound with many unique chemical properties. It contains functional groups such as bromine, iodine and trifluoromethoxy, which give it a variety of reactivity.
From the perspective of halogen atoms, both bromine and iodine are halogen elements. In chemical reactions, halogen atoms can undergo nucleophilic substitution reactions. For example, when encountering nucleophiles, bromine or iodine atoms can be replaced. Like using sodium alcohol as a nucleophilic reagent, under appropriate conditions, bromine or iodine can be replaced by alkoxy groups to form corresponding ether compounds. This reaction is of great significance for the construction of new carbon-oxygen bonds or carbon-other atomic bonds. It is often used in the field of organic synthesis to introduce specific functional groups to synthesize more complex organic molecules.
In addition, trifluoromethoxy functional groups also have unique properties. The strong electron-absorbing properties of trifluoromethoxy groups affect the electron cloud density distribution of the benzene ring. Due to the electron-absorbing of the trifluoromethoxy group, the electron cloud density of the benzene ring decreases, especially the electron cloud density of the carbon atoms and adjacent and para-carbon atoms connected to the trifluoromethoxy group changes significantly. This makes the electrophilic substitution reaction activity on the benzene ring reduce, and the reaction check point selectively changes. For example, during nitration reactions, nitro groups tend to enter their intermediate positions due to the localization effect of trifluoromethoxy groups.
In addition, the carbon-halogen bond and the carbon-oxygen bond (the carbon-oxygen bond in the trifluoromethoxy group) in this compound can be broken under different conditions. For example, under metal catalysis, the carbon-halogen bond can undergo metallization reactions to form organometallic intermediates, which can participate in subsequent coupling reactions, such as cross-coupling with another organohalide catalyzed by palladium, for the construction of carbon-carbon bonds, to achieve molecular skeleton expansion and modification, and are widely used in drug synthesis, materials science and other fields.

What is the market price of 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene?

The market price of 2-bromo-4-trifluoromethoxy-1-iodobenzene is difficult to say outright. This is because market prices are constantly changing and are influenced by many factors.
First, the trend of supply and demand is the key factor. If the market faces strong demand for 2-bromo-4-trifluoromethoxy-1-iodobenzene, and the supply is scarce, its price will inevitably rise; conversely, if there is abundant supply and little demand, the price will decline. For example, if many chemical companies compete to buy this product as a raw material for a specific product, the demand will increase sharply, and the price will also rise.
Second, production costs also have a significant impact. The price of raw materials, the simplicity of the production process, and the amount of energy consumption are all related to costs. If the price of raw materials soars, or the cost of the production process is high due to the complexity of the production process, the price of the product will rise. For example, if the purchase of raw materials is blocked and the price soars, the manufacturer will definitely increase the price of 2-bromo-4-trifluoromethoxy-1-iodobenzene in order to ensure profits.
Third, the market competition situation should not be underestimated. If there are many manufacturers of this product in the market and the competition is fierce, each manufacturer will compete for a share, or the price will be used as a weapon, which will prompt the price to decline; if the market is almost monopolized, or only a few manufacturers supply, the price may be more easily controlled by the manufacturer.
Fourth, external factors such as macroeconomic situation, policies and regulations will also be affected. If the economy is prosperous and the market is active, prices may stabilize or rise; if the economy is sluggish, demand will be sluggish, and prices may fall. If policies and regulations set restrictions on production, environmental protection, etc., it will affect production and supply, and will also indirectly affect prices.
For the exact market price of 2-bromo-4-trifluoromethoxy-1-iodobenzene, please consult the chemical product trading platform, professional chemical raw material suppliers, or follow the chemical industry information to get the latest price.