2-Bromo-4-fluoronitrobenzene, which is a crucial compound in the field of organic synthesis, has a wide range of uses.
First, in the field of medicinal chemistry, it is often used as a key intermediate. In the synthesis path of many drugs, 2-bromo-4-fluoronitrobenzene is required to build a specific molecular structure. Due to the unique chemical properties of bromine, fluorine and nitro groups, it can precisely introduce other functional groups through a series of chemical reactions, such as nucleophilic substitution reactions, so as to construct a molecular skeleton with specific pharmacological activities. With this, drugs with various effects such as antibacterial, anti-inflammatory, and anti-tumor can be synthesized.
Second, it also has important applications in the field of materials science. For example, in the synthesis of some high-performance organic optoelectronic materials, 2-bromo-4-fluoronitrobenzene can be used as a starting material to construct a conjugated structure through a multi-step reaction. The resulting organic optoelectronic materials exhibit excellent optoelectronic properties in organic Light Emitting Diode (OLED), organic solar cells and other devices, such as high charge transfer efficiency and good fluorescence quantum yield, providing a key material basis for the development of new optoelectronic devices.
Third, it also plays an important role in pesticide chemistry. It can be used as an intermediate to synthesize a variety of high-efficiency, low-toxicity and environmentally friendly pesticides. By chemically modifying it, the synthesized pesticides can be highly selective and active to specific pests or weeds, enhancing the control effect of pesticides, while reducing the adverse effects on the environment and non-target organisms.
In summary, 2-bromo-4-fluoronitrobenzene plays an indispensable role in many fields such as medicine, materials and pesticides due to its unique chemical structure and reactivity, and has made great contributions to promoting scientific research and industrial development in these fields.

2-Bromo-4-fluoronitrobenzene is an important compound in organic chemistry. Its physical properties are crucial and it has important uses in the chemical industry and scientific research.
Looking at its appearance, under room temperature and pressure, 2-bromo-4-fluoronitrobenzene often takes a light yellow to brown liquid shape, which is easy for researchers to identify initially. It has a specific odor, but it is difficult to describe it accurately in words, and it needs to be felt in person.
When it comes to the melting point, the melting point of this compound is about -13 ° C. The characteristics of the melting point make it possible to observe the transformation of its state under specific temperature conditions, which is of great significance for experimental operations such as separation, purification and identification of substances. When the temperature drops below the melting point, it will change from liquid to solid, and when it rises above the melting point, it will return to liquid.
In terms of boiling point, the boiling point of 2-bromo-4-fluoronitrobenzene is about 241 ° C. The boiling point is the critical temperature at which the substance changes from liquid to gas. At this temperature, violent vaporization occurs both inside and on the surface of the liquid. The boiling point data provides a key basis for obtaining pure 2-bromo-4-fluoronitrobenzene in separation technologies such as distillation. By controlling the temperature near the boiling point, it can be separated from other substances with large boiling points.
Density is also one of the important physical properties, and its density is about 1.76 g/cm ³. This means that the mass of 2-bromo-4-fluoronitrobenzene per unit volume is 1.76 grams. Density data plays an important role in many chemical processes, such as material ratio and mixing operations, and can help to accurately calculate the amount of required substances.
In terms of solubility, 2-bromo-4-fluoronitrobenzene is insoluble in water, which is related to the polarity of water molecules and the molecular structure of the compound itself. However, it is soluble in some organic solvents, such as common ether, chloroform, etc. This difference in solubility can be extracted and separated by different solvents in experimental operations such as extraction to obtain higher purity products.
In addition, the vapor pressure of 2-bromo-4-fluoronitrobenzene cannot be ignored. Although the specific vapor pressure value varies with temperature, in general, its vapor pressure is relatively low at room temperature. Vapor pressure reflects the difficulty of volatilization of a substance, and a lower vapor pressure indicates that the substance evaporates more slowly at room temperature. During storage and use, the loss and harm caused by volatilization are reduced.
In summary, the physical properties of 2-bromo-4-fluoronitrobenzene, from appearance, melting point, boiling point, density, solubility to vapor pressure, are related and have their own uses, laying a solid foundation for researchers to study the chemical properties of the substance, participate in the process of chemical reactions, and apply in actual production.

The synthesis of 2-bromo-4-fluoro-nitrobenzene involves various approaches. First, nitrobenzene can be initiated. Nitrobenzene is first halogenated to introduce bromine and fluorine atoms. Specifically, under specific reaction conditions, suitable halogenating reagents, such as brominating agents and fluorinating agents, act on nitrobenzene in sequence or simultaneously. In this process, the control of reaction conditions is crucial. Factors such as temperature, solvent, catalyst, etc. can significantly affect the reaction process and product selectivity. Too high or too low temperature may cause side reactions to occur and reduce the yield of the target product.
Furthermore, halogenated benzene can also be used. If halogenated benzene is used as a raw material, the nitro group is first introduced into the benzene ring through a nitration reaction. The nitration reaction usually needs to be carried out in a strong acid environment, such as the mixed acid system of concentrated sulfuric acid and concentrated nitric acid. In this system, the halogenated benzene and the mixed acid undergo an electrophilic substitution reaction, and the nitro group can be connected to the benzene ring. Then, according to the type and location of the original halogen atom on the halogenated benzene, the subsequent halogen atom substitution reaction can be carried out to introduce the desired bromine atom and fluorine atom.
In addition, some more complex organic synthesis strategies can be used, such as the reaction catalyzed by transition metals. Transition metal catalysts can effectively promote the formation and fracture of carbon-halogen bonds, so as to achieve halogenation For example, the coupling reaction catalyzed by palladium can precisely connect bromine and fluorine-containing groups to the benzene ring, and can better control the regioselectivity and stereoselectivity of the reaction. However, such methods often require harsh reaction conditions, and the cost of catalysts is high, so it is necessary to weigh the advantages and disadvantages.
All these synthetic methods have their own advantages and disadvantages. In practical application, the most suitable synthetic path needs to be carefully selected according to the specific experimental conditions, raw material availability, cost considerations and many other factors to efficiently prepare 2-bromo-4-fluoronitrobenzene.

2-Bromo-4-fluoronitrobenzene is a chemical commonly used in organic synthesis. When storing and transporting, pay attention to many matters to ensure safety and avoid accidents.
First, when storing, it should be placed in a cool and ventilated warehouse. Because of its certain chemical activity, high temperature may cause its chemical reaction to intensify, and good ventilation can disperse harmful gases that may escape in time to prevent accumulation and cause danger. The temperature of the warehouse should be strictly controlled, not too high, usually not exceeding 30 ° C. And keep away from fire and heat sources. Open flames and high temperatures may induce combustion or explosion.
Second, it should be stored separately from oxidants, reducing agents, and alkalis, and must not be mixed. 2-Bromo-4-fluoronitrobenzene comes into contact with oxidants, or undergoes violent oxidation reactions, or even explodes; interacts with reducing agents, or has uncontrollable reduction reactions; in case of alkalis, it may also cause chemical reactions, endangering safety.
Third, the container in which the product is stored must be tightly sealed. Because it may evaporate or react with certain components in the air, sealing can avoid leakage and deterioration. After taking it, the container should be sealed in time to prevent the influence of external factors.
Fourth, when transporting, it is necessary to ensure that the packaging is complete and the loading is secure. Packaging materials must be able to withstand certain external shocks and bumps, so as not to cause material leakage due to damage during transportation. The transportation process should follow relevant regulations and standards, and be equipped with necessary emergency treatment equipment and protective equipment.
Fifth, transportation personnel should be familiar with the characteristics of 2-bromo-4-fluoronitrobenzene and emergency treatment methods. In case of leakage and other accidents, it can be responded to quickly and correctly to reduce harm. If a small amount of leakage occurs, it can be absorbed by inert materials such as sand and vermiculite; if a large amount of leakage occurs, it is necessary to build a dike or dig a pit for containment, and notify professionals in time to deal with it.

The market price of 2-bromo-4-fluoronitrobenzene is hard to come to a conclusion. The price is often influenced by many factors, just like the situation changes and it is elusive.
First, the price fluctuations of raw materials have a great impact on it. If the price of bromide, fluoride and nitrobenzene required for the synthesis of this compound may rise or fall due to the origin, season, supply and demand, the cost of 2-bromo-4-fluoronitrobenzene will change accordingly, which will cause the market price to fluctuate.
Second, the quality of the production process is also related to the price. Sophisticated and advanced processes can improve output efficiency, reduce energy consumption and waste output, and reduce costs; while crude processes are inefficient and costly, and product prices will rise.
Third, the market supply and demand situation is the key factor. If many industries have strong demand for this product, such as medicine, pesticides, materials and other fields, and the supply is limited, the price will inevitably rise; on the contrary, if the demand is low and the supply is excessive, the price will inevitably fall.
Fourth, regional differences cannot be ignored. In different places, prices will also vary due to differences in transportation costs, market competition, and policies and regulations. In prosperous cities, the demand is large and the competition is fierce, and the price may be stable; in remote places, the transportation is inconvenient and the demand is small, and the price may be different from other places.
And the market price is like an endless stream of water, changing in real time. To know the exact price, you can get more accurate price information by inquiring from chemical product trading platforms, suppliers, and distributors, and considering it comprehensively. In short, its price is affected by various factors, which is difficult to hide.