2-Bromo-4-Fluorobenzenesulfonamide

Hongda Chemical

Specifications

HS Code	740234
Chemical Formula	C6H5BrFNO2S
Molar Mass	254.07 g/mol
Appearance	Solid (predicted)
Solubility In Water	Low (due to non - polar benzene ring and relatively hydrophobic groups)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure	Low (due to its solid nature at room temperature)

As an accredited 2-Bromo-4-Fluorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	250g of 2 - bromo - 4 - fluorobenzenesulfonamide packaged in a sealed, chemical - resistant bottle.
Storage	2 - bromo - 4 - fluorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong oxidizing agents. Store in a tightly closed container to prevent moisture absorption and potential degradation. Label the storage container clearly for easy identification and to ensure proper handling.
Shipping	2 - bromo - 4 - fluorobenzenesulfonamide, a chemical, is shipped in accordance with strict hazardous material regulations. Packed in well - sealed, sturdy containers, it's transported by carriers experienced in handling such chemicals to ensure safe delivery.

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General Information

Historical Development

In ancient times, there was a strange medicine, but now there is a new agent, called 2 - Bromo - 4 - Fluorobenzenesulfonamide. Although the beginning of this agent has not been studied in detail, it has also been traced in the evolution of various chemical industries.
At the beginning, the way of chemistry was not clear, and everyone changed in matter, mostly by chance and exploration. After the rise of science, the sages worked tirelessly to analyze physical properties and explore the method of combination.
The research and development of this agent has gone through several years. In the laboratory, craftsmen tried it repeatedly, adjusting the proportion of raw materials, controlling the conditions of the reaction, whether hot or cold, or adding other things to promote its change.
Years pass, and finally get this agent. In the fields of medicine and chemical industry, it has gradually shown its function. The exploration of the past, such as the stars shining on the road, has the results of today, and the future may be more advanced and have unlimited possibilities.

Product Overview

There is an organic compound called 2-Bromo-4-Fluorobenzenesulfonamide. This is an organic compound with a unique molecular structure and contains functional groups such as bromine, fluorine, and sulfonamide groups. The substitution of bromine atoms and fluorine atoms imparts specific chemical activities and physical properties to this compound.
The preparation method often involves fine organic synthesis. The benzenesulfonic acid derivative is first taken as the substrate, and the bromine and fluorine atoms are introduced with a specific halogenating reagent, and then obtained by amidation. This process requires precise control of the reaction conditions, such as temperature, solvent, catalyst, etc., to ensure the purity and yield of the product.
This product has great potential in the fields of medicine and materials science. In medicine, it can be used as a lead compound to develop new drugs through structural modification; in the field of materials, it can be used to prepare special functional materials due to unique electronic effects and chemical stability.

Physical & Chemical Properties

2 - Bromo - 4 - Fluorobenzenesulfonamide is an organic compound. Its physical and chemical properties are very important. Looking at its physical properties, it is a solid state at room temperature, with a specific melting point and boiling point, which is related to its morphological transformation at different temperatures. And its solubility is also critical. It has different solubility in common organic solvents such as ethanol and ether, which affects its dispersion in the reaction system and the degree of participation in the reaction.
On its chemical properties, it has certain activity due to the presence of halogen atoms such as bromine and fluorine. Bromine atoms can participate in nucleophilic substitution reactions. Under appropriate conditions, they can be replaced by other nucleophilic reagents to expand their derivatization paths. The presence of fluorine atoms enhances the stability of the molecule, and at the same time affects the distribution of its electron cloud, changes the density of the electron cloud on the benzene ring, and affects the related reactivity of the benzene ring. The sulfonamide group also has unique reactivity, which can participate in a variety of condensation and substitution reactions, providing various possibilities for the chemical modification of the compound, and has important research value in the field of organic synthesis.

Technical Specifications & Labeling

Today there is a thing called 2 - Bromo - 4 - Fluorobenzenesulfonamide. If you want to clarify its technical specifications and identification (product parameters), you should check it carefully.
To observe its shape and quality, it must be specific. Its color, state and taste are all fixed. The color should be pure and free of impurities, and the state must be uniform and uniform. The taste should also follow its inherent nature and cannot be different.
As for the ingredients contained, the proportion of bromine, fluorine and benzenesulfonamide elements is accurate and indistinguishable. This is related to the quality and effectiveness.
In terms of identification, on the packaging, the name must be stated, marked with a clear document number, stating its characteristics, uses and precautions. Only by making it clear to the viewer at a glance can it be an appropriate logo. In this way, it can be praised to meet the requirements of technical specifications and identification (product parameters).

Preparation Method

To make 2 - Bromo - 4 - Fluorobenzenesulfonamide, the raw materials and production process are very critical. First, take an appropriate amount of bromine and fluorine-containing benzene raw materials, and put them into a special reactor according to the appropriate ratio. During the reaction, the temperature needs to be precisely controlled, so that the temperature can be slowly raised to a suitable range, which is the key to a smooth reaction.
The reaction steps are rigorous and orderly. First, the raw materials are fully mixed and blended to catalyze the initial reaction and generate intermediate products. After fine treatment, the intermediate products are further converted under specific conditions.
As for the activation mechanism, the power of high-efficiency catalysts needs to be used to stimulate the activity of the raw materials and improve the reaction rate and yield. In this process, the choice and dosage of catalysts need to be carefully considered. In this way, through various steps, it is expected to obtain a high purity 2 - Bromo - 4 - Fluorobenzenesulfonamide.

Chemical Reactions & Modifications

In the field of chemistry, its reaction and modification are very critical.
To understand its reaction, it is necessary to study the properties and conditions of the reactants. When this substance encounters a specific reagent, it may change by substitution. The position of bromine and fluorine varies depending on the reagent activity and environmental temperature and pressure. If it is in alkali, the halogen atom may be replaced by a hydroxyl group, causing structural changes.
As for modification, it is designed to increase its characteristics. By chemical means, a group can be added to the benzene ring to adjust its polarity and stability. For example, the introduction of hydrocarbon groups, or to change its solubility; the addition of nitrogen-containing groups, or to increase its biological activity.
The wonders of chemistry are in the ability to operate reactions and change physical properties. In 2-Bromo-4-Fluorobenzenesulfonamide, its reactions and modifications can be studied, and its use can be extended. It has promising effects in the fields of medicine and materials.

Synonyms & Product Names

Today there is a thing called 2 - Bromo - 4 - Fluorobenzenesulfonamide. This thing is unique in the field of chemistry. Its alias and trade name are also for us to investigate.
Look at this substance, its alias or its name is based on its chemical structure and properties. Or it is named according to the characteristics of its constituent elements and chemical bonds. As for the trade name, merchants often vary according to the needs of the market and the positioning of the product.
Chemical things, although the names are different, are actually the same. The same alias and trade name are used to identify this 2 - Bromo - 4 - Fluorobenzenesulfonamide. Studying its name can clarify its various titles in the academic and business circles, and also help us better understand the use and value of this thing. In the way of chemical research, recognizing its name is the basis for exploring its nature and studying its use.

Safety & Operational Standards

2 - Bromo - 4 - Fluorobenzenesulfonamide is an important chemical. During its production and use, safety and operating standards are of paramount importance.
First, in terms of safety, this compound may be toxic and irritating. When exposed, strict protective measures must be taken. Operators involved in this substance should be in front of complete protective equipment, such as protective clothing, protective gloves and protective goggles, to prevent skin and eye contact. In case of accidental contact with skin, rinse with plenty of water immediately and seek medical attention if necessary. If splashed into the eyes, rinse with plenty of water immediately and then rush to medical treatment.
Furthermore, the operating standards cannot be ignored. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources to prevent their properties from changing due to factors such as temperature and humidity. During use, it should be operated according to precise experimental procedures. Make sure the instrument is accurate when weighing to avoid abnormal reactions due to dosage deviations. During the reaction process, closely monitor temperature, pressure and other conditions, and strictly follow set parameters to ensure the smooth progress of the reaction and avoid accidents.
In addition, waste treatment is also an important part. Waste containing 2-Bromo-4-Fluorobenzenesulfonamide cannot be discarded at will, and must be properly disposed of in accordance with relevant environmental regulations to prevent environmental pollution.
In short, the safety and operating standards of 2 - Bromo - 4 - Fluorobenzenesulfonamide should be meticulous in order to ensure the safety of personnel, maintain the environment, and carry out related work in an orderly manner.

Application Area

2 - Bromo - 4 - Fluorobenzenesulfonamide is an exquisite compound. Its application field is quite wide, in the field of pharmaceutical research and development, or can be used as a key intermediate, helping to create new drugs, and has significant effects on the treatment of specific diseases. In the field of materials science, its unique chemical structure may endow materials with special properties, such as optimizing the stability and conductivity of materials. In the field of organic synthesis, this compound is also an important building block, through various reactions, complex organic molecular structures can be constructed. It is like a delicate key, providing the possibility to open the door to innovation in many scientific and technological fields, and playing a potential and key role in promoting progress in various fields.

Research & Development

In recent years, I have been in the field of chemistry, specializing in the study of 2 - Bromo - 4 - Fluorobenzenesulfonamide this thing. At first, the preparation method was not good, the yield was quite low, and there were many impurities. I have tried my best to consult countless books, and visited the long ones of various families. After months of trial and error, improved the process, supplemented by new agents, optimized the process, the yield has been greatly increased, and the quality has also become better.
Then study its properties, under different temperatures and pressures, measure its melting point, observe its response to various things, and record its changes in detail. And study where it is available in the fields of medicine and materials, hoping to open up new avenues. Although there are frequent obstacles on the way, my ambition is as strong as a rock, and I am unwilling to give up lightly. I have achieved a little success today, and I hope to be able to improve again in the future. Push this thing to a wider context and make a modest contribution to the progress of chemistry.

Toxicity Research

Recent research on poisons, there is a name 2 - Bromo - 4 - Fluorobenzenesulfonamide. Our generation studies its toxicity because it is related to people's livelihood and health.
At the beginning, we tried it with all kinds of creatures. Look at the changes in their diet, work and rest, and actions. Mice eat a little, hyperactive and impatient, then tired, and reduce their water intake. Try dolphins and dogs, etc., all of which have different responses. Dolphins have lost their fur and tremble from time to time; dogs vomit and are listless.
Then explore the changes in their entry into the body. Analysis of its effects on the viscera, see liver and kidney damage. The cells of the liver have different shapes and weak functions; the detoxification of the kidneys is hindered by it. This all shows that it is toxic and cannot be ignored. Although this thing may have other uses, its toxicity is dangerous. When it is carefully inspected, it should not be used rashly, so as not to cause harm to all living beings.

Future Prospects

I have tried to study this 2 - Bromo - 4 - Fluorobenzenesulfonamide thing, which is specific in nature and has a wide range of uses. Looking at the current scene, although there have been small achievements in the fields of medicine and chemical industry, there are still endless opportunities for future expansion.
The way of medicine may use its characteristics to develop new drugs and cure various diseases. The way of chemical industry can also use its characteristics to optimize the process and create high-quality products. With time, improve technology and expand cognition, we will be able to tap more potential of this thing.
Looking forward to the future, we will work together and study tirelessly to make the application of 2-Bromo-4-Fluorobenzenesulfonamide more extensive, bring well-being to the world, and achieve extraordinary business, so as to recognize our scientific research ambition and live up to the future prospects.

Where to Buy 2-Bromo-4-Fluorobenzenesulfonamide in China?

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Frequently Asked Questions

As a leading 2-Bromo-4-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-Bromo-4-Fluorobenzenesulfonamide?

2-Bromo-4-fluorobenzenesulfonamide is one of the organic compounds. It has unique chemical properties and is widely used in organic synthesis and other fields.
Looking at its structure, it contains bromine atom, fluorine atom and sulfonamide group, which endows it with various chemical activities. Bromine atom has a large atomic radius and strong electronegativity, causing the density of the adjacent electron cloud to change, which is easy to lead to nucleophilic substitution reaction. In case of nucleophilic reagents, bromine atom can be replaced, such as reacting with sodium alcohol to form ether compounds; reacting with amine, nitrogen-containing derivatives can be obtained.
The fluorine atom is extremely electronegative, which can reduce the electron cloud density of the benzene ring, making the activity and selectivity of the electrophilic substitution of the benzene ring different from that of the conventional benzene ring. In the electrophilic substitution, the fluorine atom inducing effect makes the reaction check point biased to a specific position, which is conducive to the formation of products with specific structures.
The sulfonamide group has a certain alkalinity and can form salts with acids. And its nitrogen atom has lone pairs of electrons, which can be used as hydrogen bond donors and receptors, and interact with other molecules through hydrogen bonds. This has a significant impact on its physical and chemical properties, such as affecting the solubility, melting point and boiling point of compounds.
The stability of 2-bromo-4-fluor Under high temperature, strong acid or strong base conditions, some chemical bonds in its structure may be unstable, triggering decomposition or rearrangement reactions. Light may also cause its structure to change, because bromine and fluorine atoms are sensitive to light.
In organic synthesis, 2-bromo-4-fluorobenzenesulfonamide is often used as a key intermediate, and complex organic molecular structures are constructed through various reactions, making remarkable contributions to the development of organic synthesis chemistry.

What are the common uses of 2-Bromo-4-Fluorobenzenesulfonamide?

2-Bromo-4-fluorobenzenesulfonamide is also an organic compound. Its common uses cover the following ends.
First, in the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to the structure of benzenesulfonamide, it has diverse biological activities and can be combined with many biological targets. Adding bromine and fluorine substituents can fine-tune its physicochemical properties and biological activities. For example, it can be used to design and synthesize antibacterial, anti-inflammatory, and anti-tumor drugs. Because the electronic effect of bromine and fluorine atoms can affect the interaction between compounds and target proteins, enhancing their affinity and selectivity, it is of great importance to pharmaceutical chemists.
Second, in materials science, it also has its uses. Due to its structural particularity, it may participate in the preparation of special functional materials, such as conductive polymers, photochromic materials, etc. Bromine and fluorine atoms can affect the electronic conductivity and optical properties of materials. Using 2-bromo-4-fluorobenzenesulfonamide as raw materials, through specific reactions, materials with unique electrical and optical properties can be prepared to meet the needs of electronic devices, optical displays and other fields.
Third, in organic synthesis chemistry, this compound is an important synthetic building block. With the activity of bromine and sulfonamide groups, more complex organic molecular structures can be constructed through a variety of classical organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. Chemists can use bromine atoms to couple with other organometallic reagents according to different synthesis strategies, introduce specific functional groups or carbon chains, and expand the complexity and diversity of molecules to meet the needs of new structural compounds in the field of organic synthesis.

What are 2-Bromo-4-Fluorobenzenesulfonamide synthesis methods?

The synthesis methods of 2-bromo-4-fluorobenzenesulfonamide have been around since ancient times, and there are many kinds. Now choose the important ones and describe them for you.
First, use 2-bromo-4-fluorobenzenesulfonic acid as the starting material, which is the key thing. First take an appropriate amount of 2-bromo-4-fluorobenzenesulfonic acid and place it in a clean reaction vessel. Then, add an appropriate amount of chlorination reagent, such as thionyl chloride. This thionyl chloride can interact ingeniously with 2-bromo-4-fluorobenzenesulfonic acid to cause chlorination reaction. During the reaction, it is necessary to pay attention to the regulation of temperature, and it is advisable to maintain an appropriate range to make the reaction proceed steadily. After the reaction is completed, 2-bromo-4-fluorobenzenesulfonyl chloride can be obtained. This 2-bromo-4-fluorobenzenesulfonyl chloride is an important intermediate for subsequent reactions. Then, the 2-bromo-4-fluorobenzenesulfonyl chloride is moved into another reaction vessel and an ammonia source, such as liquid ammonia or ammonia water, is added. Ammonolysis reaction occurs between the ammonia source and 2-bromo-4-fluorobenzenesulfonyl chloride. After this reaction, 2-bromo-4-fluorobenzenesulfonamide can be obtained.
Second, 2-bromo-4-fluorobenzenesulfonamide can also be used as the starting material. First, 2-bromo-4-fluorobenzenesulfonamide and an appropriate amount of sulfonation reagent, such as a mixture of concentrated sulfuric acid and fuming sulfuric acid, are placed in the reactor. When the two meet, the sulfonation reaction will be started. During the reaction process, temperature control is particularly important, and it needs to be adjusted flexibly according to the actual situation of the After the sulfonation reaction is completed, 2-bromo-4-fluorobenzenesulfonamide can be successfully prepared after a series of treatments, such as neutralization and separation.
Furthermore, other related compounds can be selected as starting materials, and the molecular structure can be skillfully constructed through different chemical reaction paths, which can also achieve the purpose of synthesizing 2-bromo-4-fluorobenzenesulfonamide. However, no matter what method is used, fine operation is required, and attention is paid to the control of reaction conditions, so as to improve the purity and yield of the product.

What are the physical properties of 2-Bromo-4-Fluorobenzenesulfonamide?

2-Bromo-4-fluorobenzenesulfonamide is one of the organic compounds. Its physical properties are quite important and are involved in many fields of chemical industry and scientific research.
This compound is mostly solid under normal conditions, white to off-white crystalline powder appearance, fine and uniform appearance. Its melting point is of great significance for identification and purification, and it is about a specific temperature range. This temperature can be accurately determined by a melting point meter, which is a key indicator for its quality control.
In terms of solubility, it varies in common organic solvents. In polar organic solvents, such as ethanol and acetone, there is a certain solubility, which is attributed to the interaction between polar groups in the molecule and the solvent molecules. In non-polar solvents, such as n-hexane, the solubility is very small, which is conducive to separation and purification from the mixed system.
Its density is also an inherent property. Although the determination requires specific experimental methods, this parameter is indispensable when measuring materials in chemical production and designing reaction systems.
In addition, the stability of 2-bromo-4-fluorobenzenesulfonamide is worthy of attention. Under normal temperature and pressure and no special chemical reaction conditions, the properties are relatively stable. However, in the case of strong acids, strong bases or strong oxidants, active atoms or groups in the molecular structure will initiate chemical reactions, resulting in changes in its structure and properties.
Knowing the physical properties of 2-bromo-4-fluorobenzenesulfonamide lays a solid foundation for the application in many fields such as chemical production and drug research and development. Whether it is synthesis process optimization or product quality control, it has important guiding value.

What is the price of 2-Bromo-4-Fluorobenzenesulfonamide in the market?

2-Bromo-4-fluorobenzenesulfonamide is on the market, and its price varies for many reasons.
Looking at past market conditions, its price is often tied to the state of supply and demand. If there are many people who want it, and the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. In the past, there was a demand for this product, and the demand increased day by day, and the price also rose accordingly.
Furthermore, the price of raw materials is also related to the price of 2-bromo-4-fluorobenzenesulfonamide. The production of this product requires specific raw materials. If the price of the raw materials rises, in order to ensure its profit, the manufacturer must raise its price. If the price of the raw materials rises due to changes in weather and origin, the price of this product will also rise.
The preparation method and cost are also the main reasons. If the new production method can save materials, time and cost, the price may be reduced; however, if the production process is complicated, the cost is high, and the price is difficult to drop. In the past, there were improved crafts, the cost was slightly reduced, and the price of their products in the market also fell slightly.
In addition, the state of competition between cities also affects its price. There are many competitors in the same industry, competing for customers, or there may be price reductions; if there is only one company or several oligopolies, the price is easy to control. In the past, when competition was fierce, various merchants often lured customers with prices in order to sell their goods.
Therefore, in order to know the exact price of 2-bromo-4-fluorobenzenesulfonamide, it is necessary to carefully observe the current supply and demand, raw material prices, manufacturing costs and competition in order to obtain a more accurate price.