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2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene

2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    497960

    Chemical Formula C7H3BrF4
    Molar Mass 243.00
    Appearance Liquid (usually)
    Density Data needed
    Boiling Point Data needed
    Melting Point Data needed
    Solubility In Water Insoluble (likely, due to non - polar nature)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Data needed
    Vapor Pressure Data needed

    As an accredited 2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2 - bromo - 4 - fluoro - 1 - (trifluoromethyl)benzene in sealed glass bottle.
    Storage 2 - bromo - 4 - fluoro - 1 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. This helps prevent leakage and degradation due to environmental factors.
    Shipping 2 - bromo - 4 - fluoro - 1 - (trifluoromethyl)benzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring secure transit to prevent leakage and environmental/health risks.
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    2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene 2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene is also an organic compound. Tracing its historical development, early chemists explored the way of organic synthesis and studied the field of halogenated aromatics. At that time, the synthesis technology was still simple, and every time they wanted to prepare such benzene series containing special substituents, they had to think hard.
    Initially, chemists started with the basic halogenation reaction and tried to add bromine, fluorine and trifluoromethyl based on benzene ring, but the yield was quite low and impurities were abundant. After years of grinding, new catalysts and reaction conditions gradually emerged, and the yield and purity were improved.
    After the innovation of the concept of organic synthesis, the new reaction mechanism was revealed, which made the synthesis path of 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene increasingly optimized. This compound has emerged in many fields such as medicine and materials science, and its application has become wider. Its historical development is a vivid portrayal of one of the advances in chemistry.
    Product Overview
    Product Overview
    Today there is a product called 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. It is an organic compound, which is very useful in the field of chemical synthesis.
    Looking at its structure, on the benzene ring, bromine atoms, fluorine atoms and trifluoromethyl atoms are arranged according to their positions. Bromine is active, often leading to nucleophilic substitution reactions, helping organic molecules to add new groups, and changing the structure. Fluorine atoms have strong electronegativity, which changes the distribution of molecular electron clouds and has different chemical properties. They can increase biological activity and metabolic stability in the creation of medicines and pesticides. Trifluoromethyl has strong hydrophobicity, can enter the molecular structure, or make fat-soluble, and has good transmembrane transport, which is of great significance for drug development.
    Because of its unique structure and properties, it is often a key intermediate in materials science, medicinal chemistry and other fields. It may involve the preparation of new functional materials, or be used for high-efficiency and low-toxicity drug synthesis, with broad prospects. The study of this substance can add wings to the development of various fields.
    Physical & Chemical Properties
    2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene is also an organic compound. Its physical and chemical properties are quite important for my chemical research.
    Looking at its physical properties, at room temperature, this substance may be in a liquid state and has a special odor. Its boiling point, melting point, etc. are related to the transformation of its physical state and are also key parameters. The boiling point is related to the difficulty of its gasification; the melting point is determined by its solidification temperature.
    In terms of its chemical properties, it is significantly active because it contains functional groups such as bromine, fluorine, and trifluoromethyl. Bromine atoms can participate in nucleophilic substitution reactions, fluorine atoms enhance molecular stability and electronegativity, and trifluoromethyl atoms affect molecular polarity and reactivity. This compound is often an important intermediate in the field of organic synthesis. With its characteristics, it can build a variety of complex organic structures and contribute to the development of chemistry.
    Technical Specifications & Labeling
    Nowadays, the name of the chemical substance is "2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene", and its process specification and identification (product parameters) are very important. The process specification is the detailed steps and conditions for the preparation of this substance. From the selection of raw materials, it is necessary to be pure and fine, to the use of the reaction process, such as temperature, pressure, and catalyst, all need to be precisely controlled. The reaction temperature should be maintained at a specific range, and the pressure should not be a millimeter difference. The amount of catalyst is more related to the reaction rate and product purity.
    In terms of identification, the product parameters should be clearly presented. Its chemical structure needs to be accurately drawn to clarify its molecular composition. Physical properties such as melting point, boiling point, density, etc. should be carefully marked so that users can identify them. Chemical properties cannot be ignored, and information such as stability and reactivity can provide guidance for application. In this way, this product can be used correctly in the chemical field and play its due effectiveness.
    Preparation Method
    Now I want to prepare 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. The method of preparation, the selection of raw materials is crucial. You can first take a fluoroaromatic hydrocarbon, with a brominating agent, and mix the two in an appropriate proportion. The reaction steps are as follows. In a special reactor, control the appropriate temperature, about 50 to 80 degrees Celsius, so that the reaction is slow. This process requires stirring to fully contact the raw materials. After a certain time of reaction, about two to three hours, add a catalytic substance to accelerate the reaction. The catalytic mechanism is to reduce the activation energy of the reaction and make the reaction easier to proceed. After the separation and purification process to remove impurities, pure 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene can be obtained. The whole preparation process, the proportion of raw materials, the temperature of the reaction and the use of catalysis are all key, and careful operation is required to obtain good products.
    Chemical Reactions & Modifications
    There is now a product, named 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. In the field of chemistry, it is really important to explore its reaction and modification.
    Looking at its reaction, the method of organic synthesis can make it meet with various reagents to produce new substances. Such as the reaction of nucleophilic substitution, the halogen atom can easily change the structure, obtain different products, and expand its use.
    As for modification, to increase its activity, it can lead to the functional group, adjust the distribution of the electron cloud, and promote the speed of the reaction. Or seek stability, change the basis of substitution, transform the structure of space, and strengthen the force between molecules.
    The study of this chemical substance is of great use in medicine, materials and other industries. By means of reaction and modification techniques, explore the unknown, and hope to bring prosperity to various industries, add bricks and tiles, and create more possibilities.
    Synonyms & Product Names
    Today there is a thing called 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. This thing is quite important in my chemical research. Its synonymous name can also be investigated.
    In the field of chemistry, there are many things in one, and it is an ordinary thing. It may be named differently because of the past title, or the method of synthesis, or according to its use. This 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene is also called differently. Although they all refer to this thing, the titles are different, depending on the research and communication, or whether it is convenient or not.
    The name of the trade is related to the circulation of this thing in the city. Different trade names, or according to their needs, are given exclusive names to highlight their characteristics and facilitate their sales. And the name of synonyms is mostly based on the principles of chemistry and the characteristics of structure. Compared with the two, although they refer to nothing different, they are both related to business and academic, and each has its own use. When studying, you must understand all kinds of appellations, so that you can be handy, which is beneficial to both theory and industry.
    Safety & Operational Standards
    2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene Safety and Operation Specifications
    If you want to make a product of 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene, you must first clarify its safety and operation regulations. This compound has the properties of halogenated aromatics and fluorine-containing groups. When operating, you need to be careful.
    #1. Safety Protection
    Those who operate this product should wear suitable protective equipment in front of the eyes. For the first protection of the eyes, you must wear chemical safety goggles to prevent splashing and injury to the eyes. In the presence of chemically resistant clothing and gloves, the material should be made of nitrile rubber or the like, because it is resistant to the erosion of various chemicals. And the place of operation should have a well-ventilated device. If it is a fume hood, the speed and direction of the airflow should be appropriate, so that harmful gas cannot be retained.
    #2. Operating Specifications
    When taking this material, the action should be slow and stable to avoid its dumping. The measuring tool should be clean and dry to prevent impurities from mixing. When dissolving this material, a suitable solvent should be selected, and when stirring, the rate should be moderate, so that the solution should not be splashed out by boiling. During the reaction, the control of temperature and pressure is crucial. The temperature is controlled by water bath and oil bath to ensure that the temperature is uniform and suitable for the reaction. The measurement and adjustment of pressure should not be ignored, and safety valves and other devices should be prepared to prevent the risk of overpressure.
    After the reaction is completed, the treatment of the product should not be taken lightly. The method of separation and purification should be selected according to its physical properties. When distilling, pay attention to the temperature range of the distillate; when extracting, pay attention to the stratification and separation of the solvent. Waste disposal must comply with environmental protection regulations and should not be dumped at will. Poisonous and harmful waste should be collected in a specific container and properly disposed of by the company.
    All handling of this material should be based on safety and follow the rules of operation, so as to ensure the smoothness of the experiment and avoid disasters.
    Application Area
    2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene is also a chemical material. Its application is not limited. In the research and development process, it can be used as an important starting material to assist in the development of special effects, so as to have a special effect. Such as some specific bacteria or diseases, it can be synthesized to have a special effect.
    In the field of material research, it also has an extraordinary appearance. It can be used as a component of special materials to make materials special, such as increasing the stability and resistance of materials. This chemical material is like a miraculous tool of divine work, which makes it possible for researchers to create new materials, leads to the trend of application, and promotes innovation in multiple fields.
    Research & Development
    There is a product today, named 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. As a chemical researcher, it is of great significance to observe the development of this product.
    At the beginning, I explored the synthesis method of it, and tried all kinds of things, but experienced ups and downs. The choice of raw materials and the reaction rules all need to be considered. Or because the conditions are not suitable, the product is not pure, or the yield is not as expected.
    Then relentlessly study and improve the path. After repeated tests, adjusting the temperature, pressure, catalyst and other factors, the method is gradually improved. The synthesis effect is increasingly refined.
    This product has great potential in the fields of medicine, materials and so on. Such as pharmaceutical research and development, it can be used as a key intermediate to help create new drugs. In terms of materials, it may give materials unique properties.
    We should continue to study, expand its application, and promote the development of this chemical to benefit everyone.
    Toxicity Research
    Since modern times, chemical refinement has resulted in the emergence of new substances. Looking at this 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene, it is used in industry and scientific research. However, the nature of poisons cannot be ignored.
    I have tried to study its toxicity and explore its impact on living things. Try it with various living things and observe their physiological changes and behavioral differences. Observe that this thing may damage the organs of living things and disrupt the order of their metabolism.
    And it is not a stable generation in the environment. Or it is difficult to eliminate for a long time, accumulates in water and soil, enters the chain of living things, and causes poisoning to accumulate gradually.
    The study of toxicity is related to the safety of all living beings and the stability of the environment. I will work diligently and investigate carefully, so that the world can understand its benefits, use it wisely, avoid its poison, and protect the peace of life in the world and the clarity of heaven and earth.
    Future Prospects
    I have dedicated myself to the study of 2 - Bromo - 4 - Fluoro - 1 - (Trifluoromethyl) Benzene. It has great potential in the field of chemistry. The future development is expected to emerge in the creation of new materials. It may be used to develop polymer materials with specific properties, making it shine in many fields such as electronics and optics. It is also expected to serve as a key intermediate in drug synthesis to help develop new drugs with specific effects and solve people's pain. And with the advancement of science and technology, its production process may be greatly optimized, costs are reduced, and output is increased. In this way, this chemical will definitely play a crucial role in the future scientific development and industrial progress, leading our generation to a more splendid future.
    Where to Buy 2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene in China?
    As a trusted 2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Bromo-4-Fluoro-1-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene?
    2-Bromo-4-fluoro-1- (trifluoromethyl) benzene is also an organic compound. Its main uses are quite wide, and it is often a key raw material in the field of organic synthesis.
    First, in pharmaceutical chemistry, this is used as a starting material, and a molecular structure with specific pharmacological activity can be constructed through many reaction steps. Because the halogen atom and trifluoromethyl can participate in reactions such as nucleophilic substitution and coupling, and then modify the molecule, giving it the ability to bind to biological targets, it is often used to develop new drugs, such as anti-cancer and antiviral drugs.
    Second, in the field of materials science, this compound can be used as the basis for the preparation of functional materials. For example, by polymerizing with other monomers, introducing its special structure into polymer materials can improve the properties of materials, such as improving the stability and corrosion resistance of materials, or endowing materials with special optical and electrical properties, which can be used to prepare new electronic materials, high-performance coatings, etc.
    Furthermore, in the field of pesticide chemistry, it also has its place. By modifying and derivatizing its structure, pesticide products with high insecticidal and bactericidal activities can be prepared. Because its fluorine-containing structure can enhance the biological activity and environmental stability of compounds, it is helpful to develop safer, more efficient and low-residue pesticide varieties to meet the needs of agricultural production. From this perspective, 2-bromo-4-fluoro-1- (trifluoromethyl) benzene has important uses in many fields, such as organic synthesis, drug research and development, material preparation, and pesticide production, and has made great contributions to promoting the development of related industries.
    What are the physical properties of 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene?
    2-Bromo-4-fluoro-1- (trifluoromethyl) benzene is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
    Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow transparent liquid. This state makes it easy to disperse and mix in many reaction systems, and it is easy to participate in various chemical changes.
    As for the boiling point, it is about a specific temperature range, and its value varies slightly due to different ambient pressures. The appropriate boiling point allows it to follow rules in separation, purification, etc., or it can be separated from the mixture by distillation according to its boiling point difference.
    Melting point is also a key physical property that determines its physical state in a low temperature environment. The characteristics of the melting point of this compound affect its storage and transportation conditions. It is necessary to consider the appropriate ambient temperature according to its melting point to prevent unexpected changes in its state.
    Density has a certain value, which is very important in situations involving the conversion of liquid volume and mass. Density is an indispensable basis when preparing a solution of a specific concentration or accurately measuring the amount of reactants in a reaction system.
    Solubility is also a property that cannot be ignored. In organic solvents such as ether and dichloromethane, it often exhibits good solubility. This characteristic makes it possible to choose a suitable solvent to build a homogeneous reaction system in organic synthesis to promote the efficient progress of the reaction. However, in water, its solubility is poor, and the interaction between it and water molecules is weak due to the structural characteristics of the compound.
    In addition, the volatility of 2-bromo-4-fluoro-1- (trifluoromethyl) benzene also has its own characteristics. Moderate volatility affects its diffusion and distribution in the environment. During operation, its volatilization characteristics should also be considered to ensure safety and ensure accurate and controllable reaction.
    What are the chemical properties of 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene?
    2-Bromo-4-fluoro-1- (trifluoromethyl) benzene, an organic compound, is widely used in the field of organic synthesis. It has unique chemical properties and is related to many reaction characteristics and applications.
    In this compound, bromine, fluorine and trifluoromethyl are all key functional groups. Bromine atoms are highly active and can participate in a variety of nucleophilic substitution reactions. Under appropriate reaction conditions, the nucleophilic tester can attack the carbon atoms attached to the bromine atom, and the bromine ions leave, thereby forming new carbon-nucleophilic bonds. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed; when reacted with amines, nitrogen-containing derivatives may be formed.
    Fluorine atoms have strong electronegativity, which significantly affects the distribution of molecular electron clouds after introduction. It can enhance molecular polarity and change the physical and chemical properties of compounds. In some reactions, the presence of fluorine atoms affects the selectivity of the reaction check point. Due to the special influence of fluorine atoms on the density of adjacent and para-potential electron clouds, the reaction check point tends to be in a specific position during electrophilic substitution reactions.
    Trifluoromethyl also has a profound impact on the properties of compounds. It is a strong electron-absorbing group, which can greatly change the density of the benzene ring electron cloud and reduce the density of the benzene ring electron cloud. This not only affects the stability of the compound, but also affects the reactivity and selectivity. In oxidation or reduction reactions, the presence of trifluoromethyl can make the reaction conditions and products different.
    2-Bromo-4-fluoro-1- (trifluoromethyl) benzene exhibits diverse chemical properties due to the interaction of these functional groups, providing rich options for organic synthetic chemists to design and construct complex organic molecular structures.
    What are the synthesis methods of 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene?
    The method of preparing 2-bromo-4-fluoro-1- (trifluoromethyl) benzene has been explored by chemists throughout the ages, and the methods are various, and the selection is as follows.
    First, the compound containing the benzene ring is used as the starting material, and it is obtained by halogenation and the introduction of trifluoromethyl. If an appropriate benzene derivative is taken first, and the bromination reaction is carried out with a brominating agent, liquid bromine can be selected. Under the action of a catalyst such as iron powder or iron tribromide, bromine atoms are introduced into the benzene ring at a specific position. Later, fluorine atoms are introduced into the benzene ring with fluorine-containing reagents, such as potassium fluoride, etc., under suitable solvents and reaction conditions, fluorine atoms are introduced into the benz Finally, trifluoromethyl is introduced by specific reagents and conditions, such as trifluoromethylation reagents, such as sodium trifluoromethanesulfonate, etc., in an appropriate reaction system to complete the access of trifluoromethyl to obtain the target product.
    Second, it can also be synthesized by reactions involving organometallic reagents. For example, an aryl halide containing a specific substituent is first prepared and reacted with magnesium metal to form a Grignard reagent. Then, the Grignard reagent is reacted with a reagent containing trifluoromethyl to introduce trifluoromethyl. After a subsequent halogenation reaction, bromine and fluorine atoms are introduced in sequence. Under suitable conditions, 2-bromo-4-fluoro-1- (trifluoromethyl) benzene can also be obtained.
    Third, the strategy of gradually constructing the benzene ring is adopted. Using an appropriate small organic molecule as the starting material, the benzene ring is constructed through a multi-step reaction, and bromine, fluorine and trifluoromethyl are introduced in sequence during the construction process. If the compound containing carbon-carbon double bond and halogen atom is used as the raw material, through a multi-step cyclization reaction, a functional group conversion reaction, and under suitable reaction conditions and catalysts, the benzene ring structure is gradually built, and the required functional groups are introduced in sequence, and the final target compound is obtained.
    These are all common methods for synthesizing 2-bromo-4-fluoro-1- (trifluoromethyl) benzene. Each method has its own advantages and disadvantages, depending on the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, and the purity requirements of the product. Choose the best one and use it.
    What to pay attention to when storing and transporting 2-Bromo-4-Fluoro-1- (Trifluoromethyl) Benzene
    2-Bromo-4-fluoro-1- (trifluoromethyl) benzene requires careful attention during storage and transportation.
    This compound has certain chemical activity. When stored, the first environment is dry. Moisture can easily cause adverse reactions such as hydrolysis, which can damage the purity and quality of the substance. Therefore, choose a dry and well-ventilated place, away from water sources and humid places.
    Temperature is also critical. Excessive temperature may cause it to decompose and evaporate, and too low temperature may cause it to solidify, which will affect access. It is generally advisable to store in a cool place, usually 5 ° C - 25 ° C. However, the exact temperature depends on its characteristics and relevant regulations.
    In addition, this compound may be toxic and corrosive to a certain extent. When storing, it must be isolated from food, drugs and other incompatible substances to prevent contamination and reaction. And the containers used should be resistant to corrosion and have good sealing to avoid leakage.
    When transporting, the packaging must be strong and reliable. Choose suitable packaging materials, such as special glass bottles, plastic bottles or metal containers, and protect them with cushioning materials to avoid damage to the packaging due to collision and vibration.
    Transportation vehicles should also ensure that they are clean, dry, and free of other substances that may react with them. Transportation personnel should be professionally trained and familiar with their dangerous characteristics and emergency treatment methods.
    During transportation, it is necessary to strictly control temperature and humidity, follow the established route and time, and avoid high temperature periods and densely populated areas. In case of emergencies such as leaks, they should be dealt with immediately according to the emergency plan to ensure the safety of personnel and the environment from pollution.