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2-Bromo-4-Fluoro-1-Nitrobenzene

2-Bromo-4-Fluoro-1-Nitrobenzene

Hongda Chemical

Specifications

HS Code

153704

Chemical Formula C6H3BrFNO2
Molecular Weight 220.00
Appearance Solid (Typical)
Boiling Point Approximately 240 - 242 °C
Melting Point 45 - 49 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low
Purity Typically high purity for commercial products, e.g., 98%+

As an accredited 2-Bromo-4-Fluoro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - bromo - 4 - fluoro - 1 - nitrobenzene packaged in a sealed glass bottle.
Storage 2 - bromo - 4 - fluoro - 1 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is potentially flammable. Keep it in a tightly sealed container to prevent vapors from escaping. Store it separately from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Ensure proper labeling for easy identification and safety.
Shipping 2 - bromo - 4 - fluoro - 1 - nitrobenzene is a hazardous chemical. It must be shipped in accordance with strict regulations. Packed in suitable corrosion - resistant containers, transported by carriers approved for hazardous goods, with proper labeling and documentation.
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2-Bromo-4-Fluoro-1-Nitrobenzene 2-Bromo-4-Fluoro-1-Nitrobenzene
General Information
Historical Development
Fu 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene This substance originated from the path of chemical research. In the past, the sages of chemistry painstakingly studied the properties and laws of change of substances. At the beginning, in the field of organic synthesis, everyone painstakingly searched for paths to obtain this compound.
At the beginning, benzene was used as a base, and all kinds of reagents were used in sequence. The method of halogenation, the genera of bromine and fluorine were introduced, and then the technique of nitrification was applied, adding nitro to the benzene ring. During this period, Zhu Xian went through repeated trials to adjust the conditions and reagents to achieve the goodness of the reaction.
The years passed, and the method of synthesis was gradually refined. As a result, the preparation of 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene has become more and more mature, and it has gradually shown its use in medicine and materials industries.
Product Overview
Description of 2-bromo-4-fluoro-1-nitrobenzene
There is a substance called 2-bromo-4-fluoro-1-nitrobenzene. Its shape or crystalline state, the color is yellowish, and when exposed to light, it is slightly glossy. This substance has unique chemical properties and has a wide range of uses in the field of organic synthesis.
Looking at its structure, on the benzene ring, bromine, fluorine, and nitro are each based on one side. Bromine atoms give it the property of halogenation, fluorine atoms add its special activity, and nitro groups increase the diversity of its reactions. The interaction of the three makes the product exhibit specific properties in many reactions.
In the synthesis path, it can be obtained by a specific chemical method. After precise temperature control and selection of suitable reagents, this pure product can be obtained. Due to its unique chemical activity, it is a key raw material in pharmaceuticals, material research and development, etc., and can open the door to the creation of new products and contribute to the advancement of science and technology.
Physical & Chemical Properties
2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is an organic compound. Its physical properties are mostly solid at room temperature, with specific melting points and boiling points. Looking at its color, it may be colorless to pale yellow crystals, which are caused by the influence of bromine, fluorine, nitro and other groups in the molecular structure on light absorption and reflection.
Regarding chemical properties, due to the presence of nitro groups on the benzene ring, it has a certain degree of oxidation, and the electron-absorbing effect of nitro groups reduces the electron cloud density of the benzene ring and weakens the activity of electrophilic substitution. Bromine and fluorine atoms exhibit unique activities in chemical reactions due to electronegativity differences, or can participate in nucleophilic substitution and other reactions. It is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of a variety of drugs, pesticides and functional materials.
Technical Specifications & Labeling
There is a product today, named 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene. The process specifications and identification (product parameters) need to be detailed.
Its process specifications are related to the preparation method. From the selection of raw materials, it must be consistent with its purity and quantity. During operation, conditions such as temperature and pressure must be observed. If the reaction temperature is too high, the product will be variable, and if it is too low, the reaction will be slow. The speed of stirring also affects the uniformity of the reaction. Each step should be followed in sequence and should not be disturbed.
As for the logo (product parameters), the first name is 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene, which is the correct name and must not be wrong. Complex its quality, related to the purity geometry, a number of impurities. Its shape, or crystal, or liquid, color and luster. It is also necessary to clarify its molecular weight, density and other parameters in order to identify, so that users know the details, without the risk of misuse.
Preparation Method
In the process of making 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene, the raw materials need to be prepared first. Using fluorobenzene as the base, adding a brominating agent, and substituting the method, 2 - bromo - 4 - fluorobenzene is obtained. The ratio of raw materials and the temperature of the reaction must be precisely controlled.
times, take 2 - bromo - 4 - fluorobenzene, add a nitrifying agent, and according to the nitrification process, let the nitro group enter its benzene ring to form 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene. The steps of the reaction, from the beginning to the end, must not be ignored at every step.
As for the catalytic mechanism, choose the appropriate catalyst to promote the rapid progress of the reaction and increase the rate of yield. During the reaction, closely observe the situation, adjust the conditions at the right time, and ensure that the reaction goes forward. In this way, high-quality 2-Bromo-4-Fluoro-1-Nitrobenzene can be obtained.
Chemical Reactions & Modifications
2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is an important chemical product. In the field of chemical synthesis, its reaction characteristics are crucial.
In the past, the reaction of this compound was still preliminary. The substitution reactions of bromine, fluorine and nitro groups often follow the conventional path, but the yield and selectivity are not satisfactory.
At present, chemists are committed to improving the reaction. After repeated experiments, it is found that specific catalysts and reaction conditions can significantly optimize the reaction. For example, changing the temperature and solvent can regulate the reaction rate and direction. With a new catalytic system, the substitution of bromine can be more accurate, and the purity and yield of the target product can be improved. The modification of this compound has also opened up new avenues for its application in the fields of medicine, material synthesis, and brought many opportunities for chemical research and industrial development.
Synonyms & Product Names
2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is also a thing of transformation. The same name is the name of the commodity, and the things that need to be explained in the study. If you have this object, or have a name, you can use it in the same situation. Examine the ancient books and ask for the same name, so that you can make it accurate. The name of the commodity is the name of the circulation of the market and the family. If you want to study its nature and its use, you can know the name of the same commodity. It is indispensable to know the name of the same commodity, like the river and the sea on a boat. Check the text, or the local family, you will be able to learn about it. It is beneficial to the research, circulation, and use of this thing.
Safety & Operational Standards
2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is also a chemical substance. In my chemical research industry, its safety and operating standards are of paramount importance.
Where this substance is involved, the first priority is safety. Its properties are at risk. In case of improper disposal, it may cause harm. Therefore, when handling, protective gear must be complete. Wear special protective clothing to prevent its harm to the body and skin; wear protective goggles to protect your eyes from splashing; masks are also indispensable to prevent its volatile gas from entering the body.
The rules of operation should not be ignored. When taking it, the action should be steady and accurate, and do not pour it. The weighing must be in a precise device, according to the required measurement, exactly. When mixing, be slow and even, pay attention to the state of the reaction, and do not promote mutation. In the reaction environment, the temperature and humidity must be controlled to meet their needs.
When storing, it should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources to prevent explosion. Store separately from other things to avoid contact and danger. After use, the residue should not be discarded at will, and should be handled according to specific methods to avoid pollution.
All of these are the safety and operation regulations of 2-Bromo-4-Fluoro-1-Nitrobenzene. If you adhere to it strictly, you can avoid harm and profit, and move forward smoothly in the path of chemical research to ensure your own safety and the cleanliness of the environment.
Application Area
2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs. Taking the development of some antibacterial drugs as an example, this compound can be ingeniously integrated into the molecular structure of the drug through specific reaction steps, enhancing the antibacterial activity of the drug and improving the efficacy.
In the field of materials science, it also has outstanding performance. It can be used to prepare materials with special optoelectronic properties, such as organic Light Emitting Diode (OLED) materials for advanced display technologies. By precisely adjusting its chemical structure and properties, the luminous efficiency and stability of OLED materials can be optimized, and the innovation of display technology can be promoted.
In the synthesis of pesticides, 2-Bromo-4-Fluoro-1-Nitrobenzene also plays an important role. After chemical transformation, high-efficiency and low-toxicity pesticides can be prepared, effectively control crop diseases and pests, and ensure agricultural harvest, which is of great significance to the sustainable development of agriculture.
Research & Development
Today there is a product, named 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene, which is very important in the field of my chemical research. We will investigate in detail, observe its physical properties and chemical properties, and observe its reaction rules.
After months of research, we have obtained many wonderful methods to make this product. Between experiments, repeatedly adjust the conditions, temperature, pressure, and the ratio of reagents. Strive to produce a product that is pure and abundant.
Consider the use of this product again, and it can be used in medicine and materials. With time, in-depth exploration may be able to find more wonderful uses. We should make unremitting efforts to study the progress of chemistry and contribute to the development of this product, so that it can benefit everyone.
Toxicity Research
Today there is a thing called 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene. As a chemical researcher, I have studied its toxicity for a long time. The toxicity of this thing is related to the safety of all living beings and cannot be ignored.
After various experiments, observe its response to various things, and explore the changes in its entry into the body. It may damage the structure of cells and disrupt the order of physiology. Touch the skin, fear illness; enter the mouth and nose, or hurt the internal organs.
Although the toxicity is studied, there is still something to be done, but it should not be taken lightly. Those who use this thing should strictly abide by regulations, prepare for precautions, and abide by safety rules. It is hoped that the follow-up research will deepen, clarify its nature, avoid its harm, and make it a thing that benefits the world, rather than a weapon that hurts people.
Future Prospects
Wuguanfu 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene is unique and has considerable potential for future development.
In today's world, science and technology are changing day by day, and the field of chemistry is also booming. This compound may make its mark in the creation of new materials due to its structure. New materials are relevant to people's livelihood, from tough and durable appliances to light and efficient electronic components.
In addition, the road of pharmaceutical research and development may also have its uses. With its characteristics, it may help to synthesize special drugs, adding a weapon for treating diseases and diseases.
Although it is still being explored, I firmly believe that with time, 2 - Bromo - 4 - Fluoro - 1 - Nitrobenzene will be able to shine in the future development, opening up a vast world for the benefit of the world.
Where to Buy 2-Bromo-4-Fluoro-1-Nitrobenzene in China?
As a trusted 2-Bromo-4-Fluoro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-4-Fluoro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-bromo-4-fluoro-1-nitrobenzene?
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1. Agricultural Use
It is widely used in the agricultural field and can be used as a high-quality green fertilizer. 2-pentene-4-alkyne-1-ylglycine is applied to farmland and decomposed by microorganisms, which can effectively improve soil fertility and provide a variety of essential nutrients for crop growth, such as nitrogen, phosphorus, potassium and other elements, thereby promoting crop growth and improving crop yield and quality. In addition, it can also improve soil structure, enhance soil water and fertilizer retention, and make soil more suitable for crop rooting and growth.
2. Industrial Use
In industry, 2-pentene-4-alkyne-1-glycine can act as a key intermediate in organic synthesis. With its special chemical structure, it can participate in the synthesis of many complex organic compounds. For example, in the preparation of some high-value-added fine chemicals, it plays an indispensable role as a starting material or an important reaction intermediate. In the synthesis of some drugs, fragrances and high-performance materials with special functions, it is often used as a basis for a series of chemical reactions to help synthesize specific structural compounds that meet different industrial needs.
3. Potential uses in the field of medicine
In the field of medicine, although relevant research is still in the exploratory stage, there are already signs that it has potential medicinal value. Some studies have shown that it may have a positive effect on the treatment or prevention of certain diseases. For example, in the study of tumor diseases, preliminary experiments have found that it may have a certain inhibitory effect on the growth of tumor cells, but the specific mechanism of action and the safety and effectiveness of clinical application still need to be further studied and verified. In the future, it is expected that through in-depth research and development, it will be tapped into broader application prospects in the field of medicine and contribute to the cause of human health.
What are the physical properties of 2-bromo-4-fluoro-1-nitrobenzene?
2-% hydroxyl-4-ene-1-carbonyl indole, this is a rather unique class of organic compounds with many special physical properties.
Its appearance is often crystalline solid, and the texture is relatively fine. Under normal temperature and pressure, it is quite stable, but it will also undergo chemical reactions under specific conditions such as high temperature and strong oxidants.
In terms of melting point, it varies due to differences in factors such as substituents in the specific structure, and is roughly in a certain temperature range. The melting point characteristics of this compound are of great significance for its separation, purification and application under specific reaction conditions. If the melting point is high, it can maintain its own structure relatively stable during some reactions that require heating; if the melting point is low, the state of matter may change under relatively mild conditions, which brings different considerations for related operations.
Solubility is also a key physical property. In organic solvents, such as common ethanol, acetone, etc., often have a certain solubility. This property makes it possible to choose a suitable reaction solvent according to its solubility during chemical reactions to promote the smooth progress of the reaction. For example, in some organic synthesis reactions, selecting a solvent that can well dissolve 2-hydroxyl-4-ene-1-carbonyl indole can allow the reactants to fully contact and improve the reaction rate and yield. In water, its solubility is relatively poor, which also determines its limitations in applications involving aqueous systems.
In addition, the density of the compound also has its specific value. The property of density has reference value in aspects such as the judgment of stratification phenomena in mixed systems and the accurate calculation of material quantities. In practical application scenarios such as chemical production, accurately knowing its density is helpful to rationally plan the size of the reaction vessel and the proportion of material delivery, etc., to ensure the efficient and stable operation of the production process.
What are the synthesis methods of 2-bromo-4-fluoro-1-nitrobenzene?
To prepare 2-hydroxy-4-ene-1-carboxyquinoline, the following ancient methods can be used.
First, the corresponding aniline derivative and suitable reagents containing alkenyl and carboxyl groups are co-reacted under specific conditions. For example, take an aniline compound and a halogenated hydrocarbon with alkenyl and carboxyl groups in an alkaline environment, using copper salt or palladium salt as catalyst, heat and stir. Among them, the alkaline environment can be created by alkali agents such as potassium carbonate and sodium carbonate, and the catalysis of copper salt or palladium salt can increase the reaction rate and lead the reaction to the desired product. For example, an aniline and a halogenated hydrocarbon containing alkenyl and carboxyl groups are heated to an appropriate temperature in N, N-dimethylformamide (DMF) solvent under the catalysis of potassium carbonate and palladium chloride, and the target product can be obtained when stirred continuously.
Second, the quinoline parent is used as the starting material for substitution modification. First, the quinoline is halogenated at a specific position. For example, under suitable reaction conditions, the quinoline is halogenated with a halogenating agent to obtain halogenated quinoline. After that, metal-organic reagents, such as Grignard reagents or organolithium reagents, are coupled with reagents containing alkenyl and carboxyl groups. For example, take halogenated quinoline, react with alkenyl Grignard reagent in anhydrous ether or tetrahydrofuran solvent at low temperature for a certain period of time, and then introduce carboxyl reagents, such as carbon dioxide or carboxylic acid esters. After subsequent treatment, 2-hydroxyl-4-ene-1-carboxyquinoline can be obtained.
Third, a multi-step cyclization strategy is adopted. First, a number of simple organic compounds are used to construct a preliminary skeleton through condensation, addition and other reactions. For example, an aldehyde, a ketone compound and a nitrogen-containing compound are condensed under the catalysis of an acid or base to form a nitrogen-containing unsaturated intermediate. Then through the reaction of the inner ring of the electron, the alkenyl group and the carboxyl group are introduced at the same time For example, under suitable oxidation conditions or nucleophilic addition conditions, the intermediate is cyclized to form the basic structure of the target product. After appropriate modification, such as hydroxylation, 2-hydroxyl-4-ene-1-carboxyquinoline can be obtained.
All methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, etc., in order to achieve the purpose of efficient synthesis.
What are the precautions for 2-bromo-4-fluoro-1-nitrobenzene during storage and transportation?
For 2-% hydroxyl-4-ether-1-quinylnaphthalene, there are several ends that should be paid attention to during storage and transportation.
First, this physical property may be more active. When storing, choose a dry, cool and well-ventilated place. Avoid high temperatures to prevent it from mutating its properties due to heat or causing safety risks. And keep away from fire sources and oxidants, which may react violently with oxidants and cause accidents.
Second, the packaging must be tight. Choose suitable packaging materials to prevent it from contacting with outside air, water vapor, etc. If the packaging is damaged, water vapor invades, or causes chemical reactions such as hydrolysis, its quality will be damaged.
Third, during transportation, it is also necessary to ensure stability. During driving, avoid bumps and vibrations, otherwise the packaging may be damaged and the object may be endangered. And the transportation equipment should be clean and dry, with no other objects remaining, so as not to react with it.
Fourth, personnel should also be cautious in operation. Those involved in storage and transportation should have professional training to understand the characteristics of this object and pay attention to everything. During operation, wear appropriate protective equipment, such as gloves, goggles, etc., to prevent it from coming into contact with the human body and causing damage to the skin, eyes and eyes.
All of these are 2-% hydroxyl-4-ether-1-quinylnaphthalene that should be paid attention to during storage and transportation. Only by being careful can we ensure its safety and quality.
What are the effects of 2-bromo-4-fluoro-1-nitrobenzene on the environment and human health?
The influence of 2-% hydroxyl-4-ene-1-carbonyl indole on the environment and human health has been known for a long time. Although it has not been carefully observed by people today, there are traces to follow.
In terms of the environment, if these substances are scattered in mountains, rivers and rivers, they may disturb the balance of nature. In the world, all things grow and intersect each other, and the ecology is harmonious and orderly. If this substance flows into the water, the aquatic life may be harmed by it. Aquatic plants depend on water for growth and absorb nutrients from the water for a long time. This substance may hinder its absorption path, making it difficult to grow and even decay. And fish and shrimp in the water live in water and feed on aquatic plants. The change of aquatic plants will tire fish and shrimp. Or cause its reproduction to be damaged, the number is gradually decreasing, the ecological chain is interlocked, and the changes in one place affect the overall situation, and the water ecology may be seriously damaged.
As for human health, its impact should not be underestimated. The human body, such as delicate organs, viscera meridians, each perform their duties, and operate harmoniously. If this substance enters the body, or if a foreign body invades, it disturbs the peace of the viscera. The lungs are responsible for breathing, and the main qi is in and out. If the air containing this substance is inhaled, the clear function of the lungs may be affected, causing poor qi, cough and asthma, or health. The spleen and stomach are the main transportation and transformation, and the water and valley are refined to nourish the body. This substance may have the ability to harm the spleen and stomach, causing abnormal transportation and transformation, and people will lose their appetite, causing abdominal distension and abdominal pain. And the liver and kidney are responsible for detoxification and excretion. If this substance accumulates in the body for a long time, the burden on the liver and kidney will increase, or its function will be damaged, endangering the health of the whole body.
Although the ancients did not know the chemical nature of this substance, they also had an understanding of the principle that foreign objects harm the body and nature. Today, it is time to use scientific methods to investigate its effects in detail to ensure the safety of the environment and the health of the human body.