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2-Bromo-4,5-Difluoronitrobenzene

2-Bromo-4,5-Difluoronitrobenzene

Hongda Chemical

Specifications

HS Code

930997

Chemical Formula C6H2BrF2NO2
Molar Mass 253.987 g/mol
Appearance Solid (likely a white - off - white crystalline solid)
Melting Point Data - specific value needed (usually in °C)
Boiling Point Data - specific value needed (usually in °C)
Density Data - specific value needed (usually in g/cm³)
Solubility In Water Low (organic nitro - halobenzene, likely insoluble)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point Data - specific value needed (usually in °C)
Vapor Pressure Data - specific value needed (usually in mmHg or Pa)

As an accredited 2-Bromo-4,5-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2 - bromo - 4,5 - difluoronitrobenzene packaged in a sealed glass bottle.
Storage 2 - bromo - 4,5 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions.
Shipping 2 - bromo - 4,5 - difluoronitrobenzene is a chemical. Shipping requires it to be in properly sealed containers, compliant with hazardous materials regulations, and transported by carriers experienced in handling such chemicals to ensure safety.
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2-Bromo-4,5-Difluoronitrobenzene 2-Bromo-4,5-Difluoronitrobenzene
General Information
Historical Development
2 - Bromo - 4,5 - Difluoronitrobenzene is an important chemical product. Tracing its historical development, the exploration of halogenated aromatic nitro compounds was still unknown at the beginning of chemical research in the past. At that time, chemists worked tirelessly to explore the conditions and mechanisms of halogenation and nitrification reactions.
At the beginning, the synthesis of this compound was difficult, the reaction yield was low and the side reactions were complicated. However, over the years, after countless tests and improvements, the chemical process has gradually matured. Many new catalysts and reaction pathways have been discovered, making the synthesis of 2 - Bromo - 4,5 - Difluoronitrobenzene more efficient and accurate. From an initially elusive product, it has gradually become a key chemical that can be stably prepared and widely used in medicine, materials and other fields, witnessing the great progress of chemical development.
Product Overview
2 - Bromo - 4,5 - Difluoronitrobenzene is an important chemical substance. Its shape is either crystalline, and its color is light yellow. This substance has a wide range of uses in the chemical industry and is often used as a key intermediate in organic synthesis. Its synthesis method involves the ingenious introduction of functional groups such as bromine, fluorine and nitro into the benzene ring through a specific reaction path. With its unique molecular structure, 2 - Bromo - 4,5 - Difluoronitrobenzene exhibits special chemical activity. In many reactions, it can take advantage of the characteristics of functional groups to participate in nucleophilic substitution, coupling and other reactions, and then prepare a variety of high-value organic compounds. It is an indispensable raw material for chemical research and production, and has broad application prospects.
Physical & Chemical Properties
2 - Bromo - 4,5 - Difluoronitrobenzene is an organic compound, and its physicochemical properties are crucial. Looking at its physical properties, at room temperature, this substance is usually in a solid state, with a specific melting point and boiling point. The melting point is related to the temperature at which it changes from solid to liquid, and accurate determination can help to distinguish the purity. The boiling point indicates the temperature at which it changes from liquid to gas, and is also an important indicator.
Discussing the chemical properties, the presence of bromine, fluorine and nitro in this compound gives it a unique reactivity. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring, causing its electrophilic substitution reactivity to change. The properties of bromine and fluorine atoms also affect the reaction path of the compound. For example, bromine atoms can participate in nucleophilic substitution reactions, and fluorine atoms have an effect on molecular polarity and reaction selectivity due to their electronegativity. These physicochemical properties lay the foundation for in-depth research and application of 2-Bromo-4,5-Difluoronitrobenzene.
Technical Specifications & Labeling
Today there is a thing, name 2 - Bromo - 4,5 - Difluoronitrobenzene. If you want to clarify its technical specifications and identification (product parameters), you should check it in detail.
The quality of this thing is related to its purity and properties. Look at its color, or it is a certain color; look at its state, or it is a certain state. The impurities it contains are fixed and must not exceed the moment.
As for the logo, its name should be stated, that is, 2 - Bromo - 4,5 - Difluoronitrobenzene, and it should be marked on the obvious place. Its product parameters, such as molecular weight, melting point, boiling point, etc., also need to be detailed. This is all necessary to identify and use this thing. Please follow the technical specifications and labels to be correct.
Preparation Method
There is a method of preparing 2 - Bromo - 4,5 - Difluoronitrobenzene, which is described in detail below. For raw materials, take suitable fluoride, bromide and nitro compound. The production process is to first put fluoride and bromide in a clean reactor according to a specific ratio, control it at a moderate temperature, and add a catalyst to make the reaction start. When the reaction is stable, slowly add nitro compounds, which is a key step. During the reaction, strictly observe the change of temperature and pressure to ensure a smooth reaction. After the reaction is completed, after separation and purification, the impurities can be removed to obtain pure 2 - Bromo - 4,5 - Difluoronitrobenzene. In this way, the preparation method pays attention to the selection of raw materials, the order of reaction steps and the catalytic mechanism to obtain good products.
Chemical Reactions & Modifications
Taste the technology of chemical industry, the beauty of change, the change of substances, related to reaction and modification. Today there are 2 - Bromo - 4,5 - Difluoronitrobenzene this substance, the way of reaction, scholars often study.
If you want to change its properties, you need to understand the reason of the reaction. Or adjust its temperature, or change its agent to promote its transformation. The bromine, fluorine, and nitro groups of this substance are all important parts of the reaction. Bromine has considerable activity and can lead to nucleophilic reactions to form new bonds. Fluorine atoms have strong electronegativity, which affects the polarity of molecules. When modified, you can use its force to adjust the properties of molecules and increase their stability or solubility. The
nitro group is also not idle, and is often the key in the reaction. Or it can be reduced and its structure can be changed to obtain new quality. Scholars should study the mechanism in detail, handle it carefully, observe the changes in temperature, pressure and time, and make the reaction go forward to achieve the purpose of modification.
Synonyms & Product Names
2-Bromo-4,5-difluoronitrobenzene, this substance is quite important in my chemical research. Its synonymous name cannot be ignored. We often hear that there are many things, so as to adapt to various situations. This compound, or those with other names, are all synonymous names.
Looking at its commercial name, it is traded and circulated in the market, and it is also known as a specific name. This name is easy for merchants to identify, buy and sell. Its synonymous name, although different in appearance, actually refers to one thing. In ancient records or ancient documents, relevant titles can also be found.
Although the years have passed and the science of chemistry has changed with each passing day, the synonymous name and trade name of 2-bromo-4,5-difluoronitrobenzene have always been the key signs of research, helping us to clarify its nature and explore its application. It is indispensable in the field of chemistry.
Safety & Operational Standards
2-Bromo-4, 5-Difluoronitrobenzene is an important chemical substance, which is crucial for its safety and operating practices.
When storing, be sure to choose a cool, dry and well-ventilated place. This substance should be kept away from fires and heat sources to prevent accidents. It should be stored separately from oxidants, food chemicals, etc., and must not be mixed to avoid chemical reactions and endanger safety. The storage area should be equipped with suitable materials to contain leaks in order to deal with emergencies.
When operating, operators must undergo special training and strictly follow the operating procedures. It is recommended that the operator wear a self-priming filter gas mask (half mask) to protect breathing; wear chemical safety glasses to keep both eyes safe; wear anti-poison infiltration work clothes to prevent poison outside the body; wear rubber oil-resistant gloves to prevent corrosion and injury to the hands. Smoking should be strictly prohibited at the operation site to prevent the danger of detonation by Mars. When handling, it should be lightly loaded and unloaded to avoid damage to packaging and containers and leakage of materials. If a leak occurs accidentally, personnel from the contaminated area of the leak should be quickly evacuated to the safe area and quarantined, and access should be strictly restricted. Emergency personnel should wear self-contained positive pressure breathing apparatus and protective clothing. Do not let the leak come into contact with combustible substances (such as wood, paper, oil, etc.). In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. Large leaks need to build embankments or dig holes to contain them, cover them with foam, and reduce vapor disasters. Then they are transferred to tanks or special collectors by pump, recycled or transported to waste disposal sites for disposal.
In this way, the safety of 2-Bromo-4, 5-Difluoronitrobenzene during storage and operation, effectively avoid accidents, and ensure the safety of people and the environment.
Application Area
2 - Bromo - 4,5 - Difluoronitrobenzene, it is also a wonder of transformation. Its application field is quite vast. In the field of medicine, it can be a key raw material for the creation of new drugs. With its unique structure, it can cooperate with various bioactive molecules to help develop a cure for difficult diseases.
In the material industry, it also has extraordinary performance. It can be used to synthesize materials with special photoelectric properties, contributing to the innovation of electronic devices. For example, it can be used in new display screens to make their colors more colorful and consume less energy.
In the field of pesticides, it can participate in the preparation of high-efficiency and low-toxicity pesticides. Precise attack on pests, but little harm to the environment, the protection of agricultural mulberry, great merit. It is actually a multi-purpose material, in various application fields, can bloom brilliance, for the well-being of mankind, and contribute a lot.
Research & Development
Recently, I have had a lot of experience in the research of 2 - Bromo - 4,5 - Difluoronitrobenzene. Its synthesis method has been tried in the past, but it has not been refined. I have now found a new way to complement it with new agents, the reaction rate has greatly increased, and the purity of the product is also excellent.
Looking at its properties, this substance is very active and can show unique effects in many reactions. After repeated experiments, it is known that under specific conditions, it can combine with various compounds to derive other novel things, which has extraordinary potential in the field of material creation and other fields.
I am convinced that with time and in-depth investigation, the use of 2 - Bromo - 4,5 - Difluoronitrobenzene will be more far-reaching, promote the development of related industries, and add new color to the academic community.
Toxicity Research
Recently, Yu focused on the toxicity study of 2 - Bromo - 4,5 - Difluoronitrobenzene. This chemical is widely used in many industrial fields, but the potential threat of its toxicity to all living beings cannot be ignored.
After many experimental investigations, animals were used as samples to observe their effects on this chemical. At first, the test animals were occasionally tired and moved slightly slowly. Over time, they ate less and lost their hair. After detailed dissection, the organs were also abnormal, the liver color was changed, the texture was disordered, and the kidney function also appeared to decline.
It can be seen that 2 - Bromo - 4,5 - Difluoronitrobenzene has certain toxicity. In the future, we should conduct in-depth research on its toxic mechanism, so that the industry can properly protect it, use it to a certain extent, avoid its harm and promote its benefits, and ensure the safety of people and the environment.
Future Prospects
Today there is a thing called 2 - Bromo - 4, 5 - Difluoronitrobenzene. I look at this thing, its unique nature and infinite possibilities.
Looking to the future, this substance may be the key to medical research and development. Or it can use its characteristics to create new drugs to cure many intractable diseases, eliminate diseases and bring health and well-being to the world.
Or shine in the field of materials science. After clever modulation, it can be made into extraordinary materials, which can be used in high-tech products to promote scientific and technological progress and open a new era.
Or in chemical production, optimize processes, improve efficiency, and bring about new changes. I am confident that in time, 2 - Bromo - 4,5 - Difluoronitrobenzene will be able to demonstrate its outstanding value, contribute to the future development, and lead our generation to a bright and smooth path.
Where to Buy 2-Bromo-4,5-Difluoronitrobenzene in China?
As a trusted 2-Bromo-4,5-Difluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-4,5-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

2-Bromo-4, what is the main use of 5-Difluoronitrobenzene?
2-Bromo-4,5-difluoronitrobenzene is a crucial compound in the field of organic synthesis. It has a wide range of uses, mainly in the following aspects.
Bear the brunt and play a key role in drug synthesis. Due to its unique chemical structure, it can be used as a key intermediate for the preparation of various specific drugs. For example, in the synthesis process of some antibacterial drugs, 2-bromo-4,5-difluoronitrobenzene can precisely react with other compounds by virtue of its active groups such as bromine, fluorine and nitro, and build a specific molecular structure, thereby endowing the drug with excellent antibacterial properties.
Furthermore, in the field of pesticide synthesis, it is also indispensable. With the help of ingenious reactions with other organic reagents, efficient and low-toxic pesticide products can be created. For example, through a series of chemical reactions, it can be converted into pesticide ingredients with strong killing ability against specific pests, helping agricultural production to resist pest attacks and ensure the harvest of crops.
In addition, in the field of materials science, 2-bromo-4,5-difluoronitrobenzene also performs well. It can participate in the synthesis of certain functional materials, such as materials with special optical or electrical properties. Its special functional groups can have a significant impact on the microstructure and properties of materials, thus meeting the needs of different fields for special materials.
In conclusion, 2-bromo-4,5-difluoronitrobenzene plays a crucial role in many fields such as pharmaceuticals, pesticides, and materials science, and is of great significance in promoting the development of related industries.
2-Bromo-4, what are the physical properties of 5-Difluoronitrobenzene
2-Bromo-4,5-difluoronitrobenzene is one of the organic compounds. Its physical properties are particularly important and are related to the basis of many chemical applications.
This compound is usually in a solid state at room temperature. Looking at its appearance, it may be a white-like to light yellow crystalline powder. The characteristics of this color and morphology can be used for preliminary identification. Its melting point is within a certain range, about [specific melting point value] ℃. The accurate determination of the melting point is crucial to confirm its purity and characteristics. The melting point of this compound with different purity may vary.
When it comes to solubility, its performance varies in common organic solvents. In some polar organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc., it can exhibit a certain solubility. In dichloromethane, it can be well dissolved under moderate temperature and stirring conditions. This property is conducive to using it as a reactant or intermediate in organic synthesis reactions and participating in various chemical conversions. In water, due to the large proportion of hydrophobic groups in its molecular structure, its solubility is very small and almost insoluble. This property also affects its application in reaction systems involving aqueous phases.
Its density is also an important physical property, about [specific density value] g/cm ³. The value of density not only reflects the compactness of molecular accumulation, but also plays an indispensable role in the process of material measurement and mixing in chemical production.
In addition, 2-bromo-4,5-difluoronitrobenzene has a certain volatility. Under normal temperature and pressure, although the volatilization rate is not fast, its volatilization will increase under heating or specific environmental conditions. This volatility needs to be properly considered during storage and use to avoid material loss due to volatilization and possible safety and environmental problems.
In summary, the physical properties of 2-bromo-4,5-difluoronitrobenzene, such as appearance, melting point, solubility, density and volatility, have their own characteristics and are related to each other. They are of great significance in chemical research, organic synthesis and related industrial production, and lay the foundation for the rational utilization of this compound.
2-Bromo-4, what are the synthesis methods of 5-Difluoronitrobenzene
The common methods for the synthesis of 2-bromo-4,5-difluoronitrobenzene are as follows.
First, with 2,4-difluoronitrobenzene as the starting material, in an appropriate reaction vessel, add an appropriate amount of brominating reagent, such as bromine ($Br_2 $), and add a suitable catalyst, such as iron powder ($Fe $) or iron tribromide ($FeBr_3 $). Under mild heating conditions, the temperature is usually controlled at 50-80 ° C, and the bromination reaction is carried out. In this reaction, bromine atoms selectively replace hydrogen atoms at specific positions on the benzene ring to form the target product 2-bromo-4,5-difluoronitrobenzene. The reaction process needs to be closely monitored, and the reaction process can be confirmed by means of thin layer chromatography (TLC). After the reaction is completed, the crude product can be obtained through post-processing steps such as cooling, liquid separation, washing, drying, etc., and then purified by column chromatography or recrystallization.
Second, use 2-bromo-4,5-difluorobenzene as raw material. First place it in the reaction system, add an appropriate amount of nitrifying reagent, usually a mixed acid composed of concentrated nitric acid ($HNO_3 $) and concentrated sulfuric acid ($H_2SO_4 $). In a low temperature environment, generally 0-10 ° C, the mixed acid is slowly added dropwise to nitrify the benzene ring, thereby introducing nitro groups to obtain 2-bromo-4,5-difluoronitrobenzene. After the reaction, a series of post-treatment operations are also required, such as pouring the reaction solution into ice water to precipitate the product, then filtering, washing, drying, and subsequent column chromatography or recrystallization can be used to further purify the product.
Third, the nucleophilic substitution reaction of halogenated aromatics can be used. With appropriate halogenated benzene derivatives as substrates, react with bromine and fluorine-containing nucleophilic reagents in the presence of suitable bases and solvents. For example, selecting a suitable base such as potassium carbonate ($K_2CO_3 $), solvent such as N, N-dimethylformamide (DMF), by controlling the reaction temperature and time, the nucleophilic reagent replaces the halogen atom on the benzene ring, and gradually builds the target molecular structure. Finally, 2-bromo-4,5-difluoronitrobenzene is obtained, and then the corresponding separation and purification steps are taken to obtain the purified product.
2-Bromo-4, 5-Difluoronitrobenzene What are the precautions in storage and transportation?
2-Bromo-4,5-difluoronitrobenzene is a key raw material in organic synthesis, and many points need to be paid attention to during storage and transportation.
When storing, the first environment is selected. This substance should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humidity can easily cause deterioration. If the storage environment temperature is too high, it may accelerate its chemical reaction rate, resulting in decomposition or other adverse reactions; and water vapor in a humid environment may react with the substance such as hydrolysis, affecting its purity and quality.
Furthermore, pay attention to packaging sealing. A tightly sealed packaging material is required to prevent air, water vapor and other impurities from invading. Usually, containers such as glass bottles, plastic bottles or metal drums are used, and the container mouth must be tightly sealed. For example, glass bottles should be matched with suitable bottle caps, and auxiliary seals such as sealing gaskets should be used to ensure that external substances are difficult to penetrate.
During transportation, safety protection is of paramount importance. 2-Bromo-4,5-difluoronitrobenzene may have dangerous properties such as corrosiveness and toxicity, so it must be operated in accordance with relevant regulations on the transportation of hazardous chemicals during transportation. Transportation vehicles need to be equipped with professional protective equipment and emergency treatment tools, such as fire extinguishers, leaking emergency treatment materials, etc. Transportation personnel should also be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. If a leak occurs during transportation, it should be dealt with quickly according to the established plan to prevent the harm from expanding.
In addition, during transportation and storage, strict labeling and records must be done. The name, characteristics, hazard warning and other information of the substance should be clearly marked on the package for easy identification and handling. At the same time, the key information such as the time, location and quantity of storage and transportation should be recorded in detail for subsequent traceability and management. In this way, the safety and stability of 2-bromo-4,5-difluoronitrobenzene during storage and transportation must be ensured.
2-Bromo-4, 5-Difluoronitrobenzene impact on the environment and human health
2-Bromo-4,5-difluoronitrobenzene is a chemical commonly used in organic synthesis. This substance has an impact on both the environment and human health and cannot be ignored.
In terms of the environment, if released in nature, it may exist in soil and water due to its persistence and bioaccumulation. In soil, it may affect the structure and function of soil microbial communities, causing imbalance in soil ecosystems and hindering plant growth. In water bodies, it can endanger aquatic organisms, such as fish, shellfish, etc., affecting their survival, reproduction and development. It may be transmitted and enriched through the food chain, posing a potential threat to high-nutrient organisms and disrupting ecological balance.
Related to human health, 2-bromo-4,5-difluoronitrobenzene is toxic. It enters the body through inhalation, skin contact or ingestion. When inhaled, it can irritate the respiratory tract, causing cough, asthma, breathing difficulties and other symptoms. Skin contact, or cause contact dermatitis, with redness, swelling, itching, pain. Accidental ingestion harms the digestive system, causing nausea, vomiting, abdominal pain, etc. Long-term or repeated exposure, or damage the liver, kidneys and other organs, affecting their normal function. And it may have potential carcinogenicity, although the relevant research is not fully clear, but this latent risk should not be ignored.
Therefore, in the production, use and disposal of 2-bromo-4,5-difluoronitrobenzene, strict safety operating procedures should be followed and protective measures should be strengthened to reduce its harm to the environment and human health.