2-Bromo-3-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code	205003
Chemical Formula	C6H3BrFNO2
Molecular Weight	220.00
Appearance	Solid (Typical)
Color	Yellow - Brownish Yellow
Melting Point	48 - 52 °C
Boiling Point	253.5 °C at 760 mmHg
Density	1.836 g/cm³
Flash Point	107.1 °C
Solubility	Insoluble in water
Purity	Typically high purity in commercial products (e.g., 98%+)

As an accredited 2-Bromo-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	250g of 2 - bromo - 3 - fluoronitrobenzene packaged in a sealed glass bottle.
Storage	2 - bromo - 3 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential chemical reactions. Follow proper safety protocols during storage.
Shipping	2 - bromo - 3 - fluoronitrobenzene, a hazardous chemical, is shipped in well - sealed, corrosion - resistant containers. It follows strict regulations, with proper labeling indicating its properties, and is transported under controlled conditions to ensure safety.

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General Information

Historical Development

2 - Bromo - 3 - Fluoronitrobenzene is an organic compound. At the outset, chemists devoted themselves to exploring the properties of substances and seeking methods for synthesis. At the beginning, synthesis was difficult and there were many mistakes, but the will was unremitting.
After years, the technology is gradual. In the past, it was a simple method, the yield was meager, and the quality was also lacking. After new techniques emerged, from the reaction conditions and the ratio of raw materials, they were all carefully pondered. The method of catalysis was improved, and the choice of solvents was precise, so that the synthesis became more and more perfect.
Today, 2 - Bromo - 3 - Fluoronitrobenzene is used in medicine and materials, and has a wide range of uses. Looking back on the past, since the difficult start-up, it has been widely used today. The development of this compound reflects the progress of chemical technology, such as the stream of rivers, which has continued and gradually reached a better state.

Product Overview

Description of 2-Bromo-3-fluoronitrobenzene
There is a product called 2-bromo-3-fluoronitrobenzene. It is an organic compound with unique chemical properties. Looking at its structure, bromine and fluorine atoms occupy specific positions in the benzene ring, and nitro groups are also attached to the benzene ring.
This product is of great value in the field of chemical research and industrial synthesis. Due to the presence of halogen atoms and nitro groups in its structure, it can be used as a key intermediate to participate in many organic reactions. Bromine atoms are highly active and can undergo substitution reactions under appropriate conditions, introducing other functional groups to expand the structural diversity of compounds. The introduction of fluorine atoms can significantly change the physical and chemical properties of molecules, such as lipophilicity and stability. Nitro groups endow molecules with certain polarity and reactivity, and can participate in a series of reactions such as reduction, which can be used to synthesize a variety of nitrogen-containing compounds. In the design of organic synthesis pathways, 2-bromo-3-fluoronitrobenzene is often an important starting material, which provides the possibility for the preparation of organic molecules with specific structures and functions, and has potential applications in many fields such as medicinal chemistry and materials science.

Physical & Chemical Properties

2 - Bromo - 3 - Fluoronitrobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, it is mostly liquid at room temperature, with a color close to colorless or slightly yellowish, and a special odor. Its boiling point and melting point are specific values, with several boiling points and a fixed melting point, which are crucial for the process of separation and purification.
In terms of its chemical properties, it is highly active because it contains functional groups such as bromine, fluorine and nitro. Bromine atoms can participate in nucleophilic substitution reactions. Although fluorine atoms have strong electronegativity, they can also make molecules react uniquely under specific conditions. The presence of nitro groups makes this compound exhibit unique activities in some reactions, or can be used as a receptor for electrophilic reagents, causing a series of chemical changes. All these physical and chemical properties are the basis for in-depth research and application of this compound.

Technical Specifications & Labeling

Today there is a thing called 2 - Bromo - 3 - Fluoronitrobenzene. The technique of making it is related to technical specifications and identification (product parameters), which is very important.
To make this thing, you need to follow a precise method. From the choice of raw materials, you must be pure and free of impurities, in line with specific regulations. When reacting, parameters such as temperature and pressure must be strictly controlled. The rate and duration of heating up are fixed, and if you exceed it a little, you will fail.
Identify this thing and list the parameters in detail. Its color, taste and state should be clear. The purity geometry and the amount of impurities must be accurately written. This is to let others know its nature, understand its use, and make good use of it in various applications without error. Technical specifications and identification (product parameters) complement each other to ensure the quality of this product and make it usable in the world.

Preparation Method

If you want to make 2 - Bromo - 3 - Fluoronitrobenzene now, you should study the preparation method in detail. The choice of raw materials is about success or failure. You can start with benzene, add bromine, fluorine, nitro and other reagents, and react according to a certain sequence.
First make benzene and bromine catalyzed by iron, and perform a substitution reaction to obtain bromobenzene. Next, introduce a fluoro group into bromobenzene, or use a fluorine-containing reagent to react at a suitable temperature and pressure. Then introduce a nitro group, and use a mixed acid of nitric acid and sulfuric acid to control the temperature, and then obtain 2 - Bromo - 3 - Fluoronitrobenzene. When
is prepared, each reaction step needs to be carefully controlled. Temperature, pressure, and reaction time are all affected. And when setting up the method of separation and purification, remove impurities and obtain purity. The circulation mechanism also needs to be considered in order to make full use of raw materials, reduce costs and increase efficiency. In this way, a good method of this product can be obtained.

Chemical Reactions & Modifications

The chemical product is now known as 2-Bromo-3-Fluoronitrobenzene. The study of its chemical reaction and modification is quite important in the chemical industry.
For those who want to obtain this product, they need to choose the appropriate raw materials and conditions. If you start with a certain aromatic, supplemented by halogenation and nitrification, you can gradually get it. However, the choice of temperature and catalyst has a great impact. If the temperature is high, it should be sick, and then the side should be easy to produce; if the temperature is low, it should be slow, and the yield may be poor.
As for modification, its structure can be modified to increase its stability and activity. For example, adjust its substituent, or change its spatial conformation, so that it is better in the fields of medicine and materials. The research of modification must analyze the properties of its molecules in detail, and explore new ways by scientific methods, so that this product has a wider application in various industries.

Synonyms & Product Names

2 - Bromo - 3 - Fluoronitrobenzene, a synonym for this substance and a trade name, are both important symbols for chemical research. Guanfu's past chemical works have many changes in the name of the substance.
In the past, chemists used to identify this compound or give it another name according to its structural properties. In the process of synthesis, due to differences in raw materials and changes in reaction conditions, its names are also different. Or because it contains bromine (Bromo), fluorine (Fluoro) and nitro (nitro), it has different names in different research contexts.
If the trade name is required by the merchant for marketing activities, it is easy to remember and can highlight the characteristics of the product. Although synonyms and trade names are different, they all refer to 2-Bromo-3-Fluoronitrobenzene. Chemists need to clarify its many terms in their research, so as to walk the road of academic exchange and experimental exploration without confusion, so as to achieve the accuracy and depth of chemical research.

Safety & Operational Standards

2 - Bromo - 3 - Fluoronitrobenzene Safety and Operating Specifications
Husband 2 - Bromo - 3 - Fluoronitrobenzene is a common compound in chemical research. To use it properly, safety and operating standards are of paramount importance.
#1. Storage Rules
This compound should be stored in a cool, dry and well-ventilated place. Do not be near fire or heat sources to prevent it from being exposed to heat. It must be separated from oxidizing agents, reducing agents and other foreign substances to avoid chemical reactions. When storing, there are obvious warning signs to let everyone know of its danger.
#2. The essentials of operation
When operating, wear suitable protective equipment. Such as protective clothing, it can prevent it from coming into contact with the body; protective gloves, choose chemical-resistant ones to keep hands safe; protective glasses, which can prevent it from splashing into the eyes. The operating environment must be well ventilated, preferably in the fume hood, so that the volatile gas can be discharged in time.
When weighing this compound, the action should be stable and accurate. Use a complete appliance to clean it immediately to prevent residual pollution. If there is a spill, dispose of it immediately according to emergency measures. Small spills can be absorbed by inert materials such as sand and vermiculite and placed in designated containers. If a large amount spills, the personnel must be evacuated, the scene must be sealed, and the professional will handle it.
#3. Emergency strategy
If you accidentally come into contact with the skin, rinse quickly with plenty of water, followed by soap. If it enters the eye, rinse immediately with flowing water or normal saline, and then seek medical attention. If someone inhales its volatile gas, quickly move to a place with fresh air. If breathing is difficult, apply artificial respiration and rush to the hospital.
In short, during the research operation of 2-Bromo-3-Fluoronitrobenzene, strictly abide by safety and operating practices to ensure the safety of personnel and promote the smooth research.

Application Area

2-Bromo-3-fluoronitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate, which can help synthesize many specific drugs, or have antibacterial and antiviral effects, to solve patients' diseases. In material science, it can also play an important role. After specific reactions, functional materials with excellent performance can be prepared, or with unique optoelectronic properties, which can be used in optical instruments, electronic components, etc., to increase their effectiveness. And in the research and development of pesticides, it can be the basis for creating new pesticides, giving pesticides better insecticidal and herbicidal properties, and rich agricultural production. From this perspective, 2-bromo-3-fluoronitrobenzene has significant value in many practical fields, promoting the development and progress of various industries.

Research & Development

Today there is a thing called 2 - Bromo - 3 - Fluoronitrobenzene. I am a chemical researcher, and I have worked hard on its research and development.
This thing has unique properties and may be of great use in the chemical industry. In order to investigate the fact, I have conducted many experiments to observe its reaction and analyze its structure. At the beginning, the road to experimentation was full of thorns, and many problems lay in front of me. However, I uphold the heart of research and explore unremitting.
After months of work, I have gradually gained something. Knowing that it can react wonderfully with various things under specific conditions can lead to new materials. This discovery may open up a new path for the development of materials. In the future, we will continue to explore in depth, hoping to expand its application field, contribute to the prosperity of the chemical industry, and promote its rapid development to the world.

Toxicity Research

Recently, 2 - Bromo - 3 - Fluoronitrobenzene was studied in a workshop. Its toxicity study is crucial to our health and environmental well-being.
After various experiments, 2 - Bromo - 3 - Fluoronitrobenzene has certain toxicity. It may enter the body through respiration, skin contact, and ingestion. It can have adverse effects on the functions of biological cells and organs.
Looking at its effects on animals, the tested animals sometimes have abnormal behavior and physiological disorders. And in the environment, it may spread and accumulate, endangering the ecological balance.
Therefore, when developing this product, it is necessary to strictly follow the regulations and implement proper protection policies. In all aspects of production, use and disposal, caution is required to prevent it from escaping and causing harm. Research on its toxicity still needs to be continued in depth, with the hope of better understanding its nature, so as to protect the safety of humans and the environment.

Future Prospects

I have dedicated myself to the chemical product 2 - Bromo - 3 - Fluoronitrobenzene. It has already emerged in the current chemical field, but there is still a broad space for its future development.
This product may shine in the field of material synthesis. With its unique chemical structure, with time and fine research and development, it may lead to new high-performance materials, which can be used in many high-end fields such as electronics and aviation. It also has potential value in medical chemistry. If its reaction mechanism is deeply explored, it may provide key raw materials and ideas for the creation of new drugs.
I am convinced that when all the scientific researchers work together to continuously explore and innovate, 2 - Bromo - 3 - Fluoronitrobenzene will be able to demonstrate extraordinary charm in the future, contribute to the progress of mankind, and achieve a brilliant career, in order to reach an unprecedented level of development.

Where to Buy 2-Bromo-3-Fluoronitrobenzene in China?

As a trusted 2-Bromo-3-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Bromo-3-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-3-Fluoronitrobenzene?

2-Bromo-3-fluoronitrobenzene is an important intermediate in the field of organic synthesis. It has a wide range of uses, mainly found in the following numbers.
First, in the field of medicinal chemistry, it can be used as a key intermediate for the creation of various new drugs. Drug developers hope to synthesize compounds with specific physiological activities and therapeutic effects by subtly modifying and modifying their structures. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, 2-bromo-3-fluoronitrobenzene can be used as a starting material. After multi-step organic reactions, the core structure of drug molecules can be precisely constructed, laying the foundation for the development of high-efficiency and low-toxicity new drugs.
Second, in the field of materials science, it also has outstanding performance. Monomers that can be converted into functional materials through a series of reactions. For example, through polymerization with specific reagents, it is possible to prepare polymer materials with special optical and electrical properties. Such materials may be used in advanced electronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells to help improve the performance and efficiency of devices.
Third, in the synthesis of fine chemicals, 2-bromo-3-fluoronitrobenzene also plays an important role. It can be used as a precursor for the synthesis of special structural dyes, fragrances and other fine chemicals. By ingeniously designing reaction routes and taking advantage of its unique substituent properties, fine chemicals with novel structures and excellent properties can be synthesized to meet the needs of different industries for special chemicals.
In summary, 2-bromo-3-fluoronitrobenzene, with its unique chemical structure, has shown indispensable value in many fields such as drugs, materials and fine chemicals, and is of great significance for promoting the innovative development of related industries.

What are the physical properties of 2-Bromo-3-Fluoronitrobenzene?

2-Bromo-3-fluoronitrobenzene is one of the organic compounds. Its physical properties are quite unique.
First of all, its appearance, at room temperature, is mostly light yellow to brown liquid, and it has a certain fluidity. Its luster is warm, as if it contains subtle chemical mysteries.
Second, its melting point and boiling point. The melting point value is quite low, between -15 ° C and -10 ° C. This property makes the substance liquid in a relatively low temperature environment. The boiling point is relatively high, about 240 ° C to 250 ° C, indicating that it requires a higher temperature to transform into a gaseous state when heated, which is due to intermolecular forces and structural characteristics.
Then again, its solubility. It is extremely difficult to dissolve in water, because water is a polar solvent, and the polar structure of 2-bromo-3-fluoronitrobenzene molecules does not match that of water, and the two seem to be different. However, in common organic solvents, such as ethanol, ether, dichloromethane, etc., it shows good solubility and can be uniformly miscible with these solvents, just like water emulsion.
In terms of density, it is larger than water, about 1.8 g/cm ³. If it is placed in the same container as water, due to its high density, it will slowly settle under the water layer, forming a unique layered landscape with distinct boundaries.
Volatility cannot be ignored either. Under normal temperature and pressure, the volatility of this substance is weak, and the tendency of molecules to escape from the liquid phase and enter the gas phase is not very strong. However, under high temperature or decompression conditions, the volatility is increased. This phenomenon is closely related to the thermal movement of molecules and external environmental conditions. The physical properties of 2-bromo-3-fluoronitrobenzene are of great significance in many fields of organic synthesis and chemical industry. Chemists can perform operations such as separation, purification, and optimization of reaction conditions based on these properties, laying a solid foundation for the research and practice of organic chemistry.

What is the chemical synthesis method of 2-Bromo-3-Fluoronitrobenzene?

To prepare 2-bromo-3-fluoronitrobenzene, the following method can be followed. First, fluorobenzene is used as the starting material, and 3-fluoronitrobenzene can be obtained by the process of nitrification. In this step, in an appropriate reaction bottle, contain fluorobenzene, use the mixed acid of sulfuric acid and nitric acid as the nitrifying agent, and control the temperature within a suitable range, such as 50-60 ° C. Slowly add the mixed acid dropwise, and stir to apply. Among them, sulfuric acid has the effect of catalysis and dehydration, and nitric acid is the source of nitrification. After electrophilic substitution, the para-position or ortho-position of fluorobenzene is attacked by nitrophilic. Due to the ortho-localization of fluoro groups, 3-fluoronitrobenzene is obtained as the main product. After separation and purification, pure 3-fluoronitrobenzene can be obtained.
Next, 3-fluoronitrobenzene is used as the substrate for bromination. In the reaction system, add 3-fluoronitrobenzene, an appropriate amount of brominating agent, such as bromine, iron powder or iron tribromide as the catalyst, and stir the reaction at room temperature or slightly higher temperature, such as 30-40 ℃. At this time, the bromine molecule is polarized under the action of the catalyst to produce electrophilic bromine cations, which attack the benzene ring of 3-fluoronitrobenzene. Due to the synergy between the localization of the nitro group and the ortho-localization of the fluoro group, the bromine cations preferentially attack the fluoro-ortho-site to obtain 2-bromo-3-fluoronitrobenzene. After the reaction is completed, the product is separated and purified by distillation, extraction, column chromatography, etc., to obtain the target 2-bromo-3-fluoronitrobenzene. This two-step method, with clear steps and controllable conditions, is a feasible way to prepare 2-bromo-3-fluoronitrobenzene.

2-Bromo-3-Fluoronitrobenzene What are the precautions during storage and transportation?

2-Bromo-3-fluoronitrobenzene is an important raw material for organic synthesis. During storage and transportation, many matters need to be paid special attention.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. This is because of its certain chemical activity, high temperature or open flame can easily cause danger. The warehouse temperature should be controlled within an appropriate range to prevent changes in material properties.
Furthermore, it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with these substances, or violent chemical reactions, can cause serious accidents such as fires and explosions.
Packaging should also not be ignored. It is necessary to ensure that the packaging is well sealed to prevent material leakage. The packaging material should have good chemical stability, can resist the corrosion of 2-bromo-3-fluoronitrobenzene, and is sturdy and durable, and will not be damaged under normal storage conditions.
During transportation, the transportation vehicle must be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. The driving route should avoid sensitive areas such as densely populated areas and water source protection areas. The speed should not be too fast during transportation, and avoid sudden braking to prevent material leakage due to damage to the packaging.
When loading and unloading, the operator should wear suitable protective equipment, such as gas masks, chemical protective clothing, etc., and handle it lightly. It is strictly forbidden to drop, touch, and collide to prevent the packaging from breaking. In the event of a leak, emergency measures should be taken promptly to evacuate the surrounding population, isolate the leaked contaminated area, and emergency personnel should wear full masks and anti-acid and alkali work clothes to avoid contact with combustible substances. Small leaks should be collected by mixing sand, dry lime or soda ash, and large leaks should be built into embankments or dug for containment. They should be transferred to a tanker or a special collector by pump for recycling or transportation to a waste treatment site for disposal.

2-Bromo-3-Fluoronitrobenzene impact on the environment and human health

2-Bromo-3-fluoronitrobenzene is one of the organic compounds. It has a great impact on the environment and human health.
First of all, its impact on the environment. This compound has certain chemical stability and is difficult to degrade in the natural environment. If it accidentally flows into the water body, it can cause water pollution. Organisms in the water bear the brunt, or cause their physiological disorders. Such as fish, it may affect their respiration and reproduction, the growth or hindrance of juvenile fish, and the population may decrease as a result. In the soil, it may affect the activity of soil microorganisms, destroy the soil ecological balance, and then affect the absorption of nutrients by plant roots, hinder plant growth and development, and lead to reduced crop yields.
As for the impact on human health, it should not be underestimated. 2-Bromo-3-fluoronitrobenzene can enter the human body through respiratory tract, skin contact and accidental ingestion. It has irritating effects on the respiratory tract. After inhalation, it may cause symptoms such as cough, asthma, breathing difficulties, long-term exposure, or cause chronic respiratory diseases. Contact with the skin can cause skin allergies, redness, swelling, itching, and in severe cases, it may damage the skin barrier function, making the skin more vulnerable to other harmful substances. If ingested by mistake, it can damage the digestive system, cause nausea, vomiting, abdominal pain and other symptoms, and even cause organ damage. And this compound has potential carcinogenicity. Long-term exposure will increase the risk of cancer in the human body. Therefore, in the production, use and disposal of 2-bromo-3-fluoronitrobenzene, it is necessary to exercise caution and take proper protective and handling measures to reduce its harm to the environment and human health.