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2-Bromo-3,5-Difluoro-1-Nitrobenzene

2-Bromo-3,5-Difluoro-1-Nitrobenzene

Hongda Chemical

Specifications

HS Code

834684

Chemical Formula C6H2BrF2NO2
Molecular Weight 238.986
Appearance Typically a solid
Physical State At Room Temperature Solid
Boiling Point Data may vary, but generally in the range relevant to aromatic bromo - nitro - fluoro compounds
Melting Point Specific value may need to be sourced from experimental data
Density Needs experimental determination
Solubility In Water Low solubility in water as it is an aromatic non - polar - like compound
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point Requires experimental determination
Vapor Pressure Low vapor pressure due to its relatively high molecular weight and solid state

As an accredited 2-Bromo-3,5-Difluoro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - bromo - 3,5 - difluoro - 1 - nitrobenzene in a sealed glass bottle.
Storage 2 - bromo - 3,5 - difluoro - 1 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage. It's best to store it in a dedicated chemical storage cabinet, separated from incompatible substances to avoid potential reactions and ensure safety.
Shipping 2 - bromo - 3,5 - difluoro - 1 - nitrobenzene is shipped in properly sealed, corrosion - resistant containers. It follows strict regulations for hazardous chemicals, with appropriate labeling for safe transportation.
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2-Bromo-3,5-Difluoro-1-Nitrobenzene 2-Bromo-3,5-Difluoro-1-Nitrobenzene
General Information
Historical Development
2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene is also an organic compound. At the beginning of its research and development, chemists worked hard to explore the synthesis method. At the beginning, the experiment suffered many setbacks, the yield was low, and there were many impurities. However, the researchers were unyielding, delving into the reaction mechanism and improving the conditions. After years, progress was gradually made. First, a suitable solvent was found to make the reaction more smooth; then the temperature and catalyst were optimized to improve the yield. After long-term research, the synthesis process was improved day by day, and this compound could be produced stably. It emerged in the fields of medicine, materials and other fields, and contributed to the development of scientific research and industry. Its historical evolution is a witness to the unremitting efforts of researchers.
Product Overview
There is now a substance called 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene. This is an organic compound. In its molecular structure, bromine atom, difluoro atom and nitro group are on one side above the benzene ring.
Bromine is active and is often a key check point in organic reactions, which can lead to nucleophilic substitution. The difluorine atom adds to the stability of its molecule, and because of the strong electronegativity of fluorine, it affects the polarity and reactivity of the molecule. The nitro group is rich in oxidation and also has a great influence on the chemical properties of the compound.
This substance is widely used in the field of organic synthesis. It can also be used as an intermediate for the preparation of special drugs, leveraging the reactivity of each group to build complex drug molecular structures; it can also be a cornerstone for the development of new materials, endowing materials with unique properties due to their unique chemical properties.
Physical & Chemical Properties
2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene is an important chemical substance. Its physical and chemical properties are unique. Looking at its physical properties, it is mostly solid at room temperature, colored or light yellow, with a specific melting point and boiling point. The value of the melting point is the critical temperature at which it changes from solid to liquid state, which is related to its phase state in a specific environment. The boiling point determines the temperature at which it can be liquefied into gaseous state. In terms of chemical properties, it contains functional groups such as bromine, fluorine, and nitro, which are quite active. Bromine atoms can undergo substitution reactions and can be replaced by other groups under suitable conditions. The presence of nitro groups enhances its oxidation and can participate in many redox reactions. The properties of fluorine atoms make the stability and reaction selectivity of molecules unique. All kinds of properties lay a solid foundation for its application in organic synthesis and other fields.
Technical Specifications & Labeling
Today there are 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene. This product is very important in the chemical industry. Its process specifications and identification (commodity parameters) are the key to our research.
On its process specifications, from the selection of raw materials, it is necessary to be pure and free of impurities, and to be accurate. The reaction conditions, temperature and pressure must be strictly set and precisely controlled. For example, cooking in a tripod, the heat is appropriate, and it can be better. The order of steps is interconnected and cannot be disrupted.
As for the identification (commodity parameters), the characteristics of this product, such as color, smell, and purity geometry, must be clearly marked. Its molecular weight, boiling point, melting point and other data should also be accurate and accurate, so that the supplier can understand it and make it correct. In this way, only in the chemical industry can it travel smoothly and achieve the desired effect.
Preparation Method
To prepare 2-Bromo-3,5-Difluoro-1-Nitrobenzene, first take fluorobenzene as the base, and nitrate to obtain 3,5-difluoro-nitrobenzene. With its bromination reaction with bromine under appropriate catalysis. The raw material used, fluorobenzene needs to be purified, and bromine also seeks its high quality.
The preparation process is as follows: In a suitable reactor, control the temperature in a suitable range, first put 3,5-difluoro-nitrobenzene, then slowly add bromine, and add an appropriate amount of catalyst at the same time. During the reaction, pay attention to the change of temperature, fine-tune it in a timely manner, so that the reaction is smooth. After the reaction is completed, the step of separation and purification is completed. Pure 2-Bromo-3,5-Difluoro-1-Nitrobenzene was obtained by distillation, extraction and other methods to remove impurities. The transformation mechanism is based on the electrophilic substitution of aromatic hydrocarbons. Nitro and fluorine atoms affect the electron cloud of benzene ring, so that bromine is substituted at the site of selection to form this product.
Chemical Reactions & Modifications
There is now a substance called 2-Bromo-3,5-Difluoro-1-Nitrobenzene. In the field of chemistry, its reaction and modification are studied by us.
Looking at the reaction, specific methods are often used to make bromine, fluorine, nitro and other groups on the benzene ring, or change their position, or change their susceptibility. This all depends on various reagents, such as nucleophiles, electrophilics, etc., by means of suitable conditions, such as temperature, pressure, catalyst, etc., to promote the reaction.
As for modification, either to increase its stability or to change its activity to suit different needs. Such as adding a group or removing an atom, the structure and properties of the molecule are changed. This requires fine operation to achieve the desired results.
In the process of chemical research, explore the reaction and modification of this substance, hoping to make new discoveries and contribute to the development of chemistry.
Synonyms & Product Names
2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene This thing, its synonyms and trade names have been explored since ancient times. There are many names for chemical things, although the essence is one, but the names are different and the same is used.
View this 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene, or those named for their characteristics, or different names due to the production method. Its synonyms are a precise description of its chemical nature, from the aspects of chemical structure, constituent elements, etc., to represent the same thing in different words. As for the trade name, the merchant has established another name in order to recognize its uniqueness, or to make it easy to recite and promote, or to highlight its use and quality.
As in the past, many chemical products have different synonyms and trade names due to changes in times and regions. However, the root of it all refers to this 2 - Bromo - 3, 5 - Difluoro - 1 - Nitrobenzene. The detailed study of these two is of great benefit to the research of chemistry and the application of industry, which can make people in the industry clear and discerning without confusion.
Safety & Operational Standards
Today there are chemical products, name 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene. This product is related to safety and operating standards, and should not be ignored.
It is strong in nature. When storing it, choose a cool, dry and well-ventilated place. Do not be near fire or heat to prevent unexpected changes. It must be separated from easy and explosive things to avoid contact and disaster.
As for the operation, the operator must wear appropriate protective clothing, goggles and anti-poison equipment. Do not touch it with naked hands, and do not let the skin contact it. During the operation, make sure the ventilation is smooth to avoid the accumulation of toxic gases and harm to the body. If you are careless, touch the skin, flush it with a lot of water as soon as possible, and then seek medical treatment.
The method of use must be based on precise regulations. The amount of quantity and the length of time must not be wrong. The equipment used should also be clean and clean, so as not to mix with miscellaneous quality, which will damage its nature and change in a mess.
Discard it and discard it must also be done in accordance with the law. Do not pour it at will, when gathered and disposed of, in accordance with environmental regulations, turn harm into benefit, or dispose of it properly, so as to ensure the safety of the four regions and keep people and animals safe. In this way, the essentials of safety and operation can be obtained, so that this thing can be used without suffering.
Application Area
2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene is a delicate chemical substance with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and have significant effects on the treatment of many diseases. In the field of materials science, it may be able to participate in the creation of high-performance materials, giving materials unique physical and chemical properties, such as enhancing their stability and changing their optical properties. In organic synthetic chemistry, this substance can be used as the foundation for building complex organic molecules. With its special chemical structure, various novel organic compounds can be derived through ingenious chemical reactions, which greatly enriches the variety of organic compounds and provides a variety of options and possibilities for the development of related fields. It is an indispensable and important substance in chemical research and application.
Research & Development
Recently, in my workshop, I focused on the chemical 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene. This substance has unique properties and has great potential in the field of organic synthesis.
I began to explore the way of its preparation by various exquisite methods. After repeated trials, I improved the reaction conditions, such as temperature, pressure, and catalyst ratio, in order to obtain higher yield and purity. In the analysis of the reaction mechanism, I also paid great attention to the transformation of each step, hoping to clarify its inner principle.
Furthermore, observe its performance in different chemical reaction systems and try to expand its application scope. It may find new opportunities in many fields such as pharmaceutical synthesis and material research and development. This is the direction of my recent research, hoping to make breakthroughs and contribute to the development of this compound, so that its potential can be fully developed in the world.
Toxicity Research
Recently, 2-Bromo-3,5-Difluoro-1-Nitrobenzene has been studied, and its toxicity is quite important. Looking at its structure, bromine, fluorine, and nitro groups have special chemical properties, or lead to toxicity.
After various experiments, this compound may interfere with the normal metabolism of cells in biological systems. After entering the organism, it may interact with macromolecules such as proteins and nucleic acids, disrupting their functions. Cell experiments show that it has the effect of inhibiting proliferation on specific cell lines, showing abnormal cell morphology.
Animal experiments also show that small doses of poisoning show that the behavior of the tested animals is different from usual, and the organs or pathological changes are present. However, the study of toxicity still needs to be widely studied to clarify its toxic mechanism, dose-effect relationship, etc., so as to provide a solid basis for the protection and application of this chemical to avoid environmental and biological harm.
Future Prospects
I have tried to study 2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene. Thinking about its future, what my heart wants is that it can be widely used in various fields. Looking at the current state, although it has achieved small success, there is still a long way to go, and there are still many things to be explored.
I hope that in the field of pharmaceutical creation, it can open up new ways for healing diseases. Or it can be used as a key intermediate to help new drugs come out and solve the suffering of patients. At the end of material research and development, I hope it can endow materials with specific properties, such as enhancing their stability and optimizing their optical properties, so that materials can shine in electronics, optics and other industries.
Although I don't know what the future holds, I firmly believe that with time and advanced skills, 2 - Bromo - 3, 5 - Difluoro - 1 - Nitrobenzene will be able to emerge, achieve great things, expand the prospects, and add new colors to the world. This is what I hope for.
Where to Buy 2-Bromo-3,5-Difluoro-1-Nitrobenzene in China?
As a trusted 2-Bromo-3,5-Difluoro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-3,5-Difluoro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

2-Bromo-3, what are the physical properties of 5-Difluoro-1-Nitrobenzene
2-Bromo-3,5-difluoro-1-nitrobenzene is one of the organic compounds. Its physical properties are quite important and are widely used in various fields of chemistry.
First of all, under normal conditions, this compound is mostly light yellow to light brown crystalline powder. The appearance of this color state is due to the synergistic action of functional groups such as bromine, fluorine and nitro in its molecular structure. Bromine atoms have a large atomic radius and polarizability, fluorine atoms are extremely electronegative, and nitro groups are strong electron-absorbing groups. The coexistence of the three causes the molecules to change their light absorption and scattering characteristics, thus revealing this color state.
When it comes to the melting point, it is about a specific temperature range, and this value is closely related to the intermolecular force. Van der Waals forces, hydrogen bonds, and electrostatic interactions between molecules work together to maintain the stability of the crystal structure. The introduction of bromine and fluorine atoms increases the intermolecular dispersion force, while the nitro group enhances the molecular polarity and strengthens the electrostatic interaction, so that the melting point is in the corresponding range. The specific value can be accurately determined by experiments.
The boiling point is also a key physical property. Due to its high molecular polarity and strong intermolecular force, in order to convert the liquid phase to the gas phase, sufficient energy needs to be supplied to overcome the intermolecular attractive force, so the boiling point is higher. The determination of boiling point requires rigorous experimental operation, considering factors such as pressure, because it is significantly affected by external conditions.
In terms of solubility, 2-bromo-3,5-difluoro-1-nitrobenzene exhibits some solubility in organic solvents such as dichloromethane, chloroform, tetrahydrofuran, etc. This is due to the existence of similar polarities between organic solvents and the compound molecules or the formation of specific interactions. However, its solubility in water is very small, because the polarity of water molecules is quite different from that of the compound, and it is difficult for the two to form effective interactions.
Density is also a property that cannot be ignored. The density of the compound depends on the molecular weight and the degree of molecular packing. Bromine and fluorine atoms are relatively heavy relative to atoms, which increases the molecular weight. Coupled with the regularity of molecular structure, their density is relatively high. It can be accurately measured by experimental methods and according to the Archimedes principle.
2-Bromo-3,5-difluoro-1-nitrobenzene The physical properties are determined by its molecular structure. It has key reference value in organic synthesis, drug development, materials science and other fields, helping researchers to rationally design experiments, predict reaction processes and product properties.
2-Bromo-3, what are the main uses of 5-Difluoro-1-Nitrobenzene
2-Bromo-3,5-difluoro-1-nitrobenzene is a crucial compound in the field of organic synthesis. Its main uses are extensive and are described as follows:
First, in the field of medicinal chemistry, this compound is often used as a key intermediate. Due to the structure of fluorine, bromine and nitro groups, it has unique physical and chemical properties and can participate in a variety of chemical reactions to build complex drug molecular frameworks. In the development of many new drugs, 2-bromo-3,5-difluoro-1-nitrobenzene is often used as the starting material. After ingenious reaction design, various active groups are introduced to synthesize compounds with specific pharmacological activities for the prevention and treatment of diseases.
Second, in the field of materials science, it also plays an important role. With its unique chemical structure, it can be integrated into polymer materials through specific reactions, thereby improving the properties of materials. For example, it can enhance the stability and corrosion resistance of materials, or endow materials with special optical and electrical properties, providing the possibility for the creation of new functional materials.
Third, in pesticide chemistry, this compound can be used as an important intermediate for the synthesis of high-efficiency pesticides. The introduction of fluorine atoms can often significantly enhance the biological activity of pesticides, reduce toxicity and enhance environmental compatibility. Based on 2-bromo-3,5-difluoro-1-nitrobenzene, high-efficiency pesticides for specific pests or diseases can be synthesized through a series of reactions, which contributes to the sustainable development of agriculture.
In short, 2-bromo-3,5-difluoro-1-nitrobenzene has important uses in drugs, materials, pesticides and many other fields due to its special structure, providing an important material basis and synthesis starting point for the development of various fields.
2-Bromo-3, what are the synthesis methods of 5-Difluoro-1-Nitrobenzene
There are several common methods for the synthesis of 2-bromo-3,5-difluoro-1-nitrobenzene. One is to use compounds containing benzene rings as starting materials, and introduce bromine and fluorine atoms by halogenation reaction. Under specific reaction conditions, suitable halogenating reagents, such as brominating agents and fluorinating agents, act on the benzene ring in sequence or at the same time, and precisely regulate the reaction check point, so that the bromine and fluorine atoms fall into the target 2, 3 and 5 positions respectively.
Furthermore, nitro can be introduced into the benzene ring through nitration reaction. This reaction requires the selection of suitable nitrogenation reagents, such as a mixed acid system of nitric acid and sulfuric acid, under strict temperature control and other conditions, to promote the successful connection of nitro to the benzene ring 1 position. During this period, factors such as the ratio of reactants, reaction temperature and time all have a great influence on the reaction process and product purity.
In addition, there are also methods of functional group transformation. First prepare benzene derivatives with convertible functional groups, and gradually convert the functional groups into bromine, fluorine and nitro groups through multi-step reactions. Although this approach may be complicated, the reaction route can be flexibly selected according to actual needs to improve the selectivity and yield of synthesis. Each method has its own advantages and disadvantages. In actual synthesis, factors such as raw material availability, cost, and difficulty of reaction conditions need to be comprehensively considered to select the optimal synthesis strategy.
2-Bromo-3, what are the precautions in storage and transportation of 5-Difluoro-1-Nitrobenzene
2-Bromo-3,5-difluoro-1-nitrobenzene is an important compound in organic chemistry. During storage and transportation, many matters need to be paid attention to.
Store first. This compound may be unstable in nature, so it needs to be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, it is easy to cause decomposition or other adverse reactions when heated, so it is the first thing to stay away from heat sources and fire sources. And it is necessary to avoid direct exposure to strong light, which may also cause photochemical reactions and damage its quality. Storage containers should be made of corrosion-resistant materials, because they contain bromine, fluorine, nitro and other groups, or react with some materials. Glass containers are preferred because they are chemically stable and difficult to interact with compounds. At the same time, they must be tightly sealed to prevent contact with moisture, oxygen and other components in the air. Moisture or hydrolysis, oxygen or oxidation will affect its purity and quality.
As for transportation, it is also necessary to pay great attention. It should be implemented in accordance with relevant dangerous chemical transportation regulations. Because it may be toxic and corrosive to a certain extent, transportation personnel must be professionally trained and familiar with its characteristics and emergency treatment methods. During transportation, ensure that the container is stable, avoid collisions and vibrations, and prevent the leakage of compounds due to damage to the container. If choosing road transportation, the vehicle needs to be equipped with corresponding emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. If it is transported by rail or air, it is necessary to strictly follow the corresponding special regulations and requirements. And the transportation documents should be detailed and accurate, with information such as the name, nature, hazard and emergency measures of the compound, so that relevant personnel can deal with emergencies.
In conclusion, 2-bromo-3,5-difluoro-1-nitrobenzene has strict requirements on environmental conditions, container selection, personnel operation and emergency preparedness during storage and transportation, so as to ensure its safety and quality.
What is the market price of 2-Bromo-3, 5-Difluoro-1-Nitrobenzene?
I look at the "2 - Bromo - 3,5 - Difluoro - 1 - Nitrobenzene" you are inquiring about. This is an organic compound, and its market price varies for a variety of reasons.
First, the impact of purity is quite large. If the purity is very high, it is almost analytical purity or higher, and it is suitable for high-end scientific research, pharmaceuticals and other fields, its price will be high. However, if the purity is slightly lower, it is only for general industrial use, and the price is relatively low. For example, if the purity is above 99%, the price per gram may range from tens to hundreds of yuan; while if the purity is about 95%, it may be only a few yuan per gram.
Second, the state of supply and demand is also critical. If the market demand for this product is strong and the supply is limited, if the demand for a new type of drug is greatly increased, the supply will exceed the demand, and the price will rise. On the contrary, if the market demand is low, there are many manufacturers, and the supply exceeds the demand, the price will decline.
Third, the production cost also affects the price. The price of raw materials and the complexity of the production process are all cost components. If the raw materials are rare and expensive, or the production requires complex processes, expensive equipment and a lot of energy consumption, the cost is high, and the price is not low.
Fourth, the purchase quantity is also related to the price. For bulk purchasers, merchants often give them at preferential prices, with small profits but quick turnover. If you buy in small quantities, per gram or at the regular price; if you buy several kilograms at one time, the price per gram may be significantly discounted.
In summary, it is difficult to determine the market price of this compound due to the lack of details on the specific purity, supply, demand and purchase quantity. However, the price fluctuates between a few yuan and a few hundred yuan per gram.