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2-Bromo-3,4-Difluoro-1-Methoxybenzene

2-Bromo-3,4-Difluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code

965943

Name 2-Bromo-3,4-Difluoro-1-Methoxybenzene
Chemical Formula C7H5BrF2O
Molar Mass 223.014 g/mol
Appearance Liquid (usually)
Boiling Point Data may vary, typically in a certain range depending on purity
Melting Point Data may vary
Density Data may vary
Solubility In Water Insoluble (expected, due to non - polar nature of aromatic part)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Data may vary based on temperature
Flash Point Data may vary

As an accredited 2-Bromo-3,4-Difluoro-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - bromo - 3,4 - difluoro - 1 - methoxybenzene in a sealed chemical - grade bottle.
Storage 2 - bromo - 3,4 - difluoro - 1 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of a material resistant to chemical corrosion, like glass or certain plastics. Avoid storing it near oxidizing agents or reactive substances to prevent potential chemical reactions.
Shipping 2 - bromo - 3,4 - difluoro - 1 - methoxybenzene is shipped in sealed, corrosion - resistant containers. Packaging ensures protection from physical damage. It follows strict hazardous chemical shipping regulations to guarantee safe transportation.
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2-Bromo-3,4-Difluoro-1-Methoxybenzene 2-Bromo-3,4-Difluoro-1-Methoxybenzene
General Information
Historical Development
In ancient times, chemical researchers investigated the changes of matter and often encountered novel things. Today there is 2-Bromo-3,4-Difluoro-1-Methoxybenzene, a chemical whose birth has also gone through years. In the past, chemistry was first developed, and researchers worked in simple rooms, analyzing simple tools one by one. At first, the understanding of halogenated and alkoxy benzene compounds was still shallow, and only a little knowledge of their basic properties. However, the researchers were eager to explore, and they worked tirelessly. After countless experiments, adjusting the reaction conditions, and trying different raw materials. From ignorance and exploration, to gradual understanding, the method of synthesizing this compound was gradually clarified. With the passage of time, the accumulation of knowledge, and the refinement of technology, the synthesis method is becoming more and more perfect, and the yield is also gradually increasing. 2-Bromo-3,4-Difluoro-1-Methoxybenzene can be produced stably, leaving a unique track in the path of chemical research.
Product Overview
There is now a compound called 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene. It is an organic compound with a halogen atom and a methoxy group. Looking at its structure, bromine atoms, fluorine atoms and methoxy groups each occupy a specific position in the benzene ring. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate. With its bromine atom activity, it can introduce various functional groups through substitution reactions to expand the molecular structure. The properties of fluorine atoms can change the physical and chemical properties of compounds, such as improving fat solubility and enhancing stability. The presence of methoxy groups also affects the distribution of electron clouds in molecules, which is related to reactivity and selectivity. It holds potential value in medicine, material synthesis, etc., and can contribute to the creation of novel drugs and advanced materials.
Physical & Chemical Properties
2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene is also an organic compound. Its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific color, taste and phase state. The number of its boiling point and melting point is related to the change of its physical state, which has a lot to do with its separation and purification. As for its chemical properties, it has unique reactivity due to the presence of bromine, fluorine, and methoxy functional groups. Bromine atoms can initiate nucleophilic substitution reactions, while fluorine atoms have strong electronegativity, which affects the distribution of electron clouds in molecules, resulting in different reactivity in adjacent and para-sites. Methoxy group is the power supply group and also has a great influence on its chemical behavior. This compound can be used as a key intermediary in the field of organic synthesis to synthesize other complex organic molecules. The study of its physical and chemical properties is of great significance to the development of the chemical industry.
Technical Specifications & Labeling
Today there is a product, name 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene. Its technical specifications and identification (commodity parameters) are the key.
Looking at this substance, the technical specifications need to be accurate. From the selection of raw materials, it is necessary to be pure and free of impurities, in line with established standards. During preparation, temperature, pressure and other conditions should be strictly controlled, and there should be no slight differences. Each step follows the rules to ensure a smooth and orderly reaction to ensure the quality of the product.
Identification (commodity parameters) should not be underestimated. Its ingredient content should be clearly marked so that the user can see it at a glance. Physical properties, such as color and morphology, should be accurately described. Such specifications and labels are related to the application and circulation of this product, and must not be ignored. Only by strictly adhering to technical specifications and distinguishing labels (commodity parameters) can the quality of 2-Bromo-3,4-Difluoro-1-Methoxybenzene be constant and its performance can be fully demonstrated in various uses.
Preparation Method
This product is made of 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene, and its raw materials should be prepared first. Take an appropriate amount of fluorobenzene, and brominate the bromine atom into its benzene ring to obtain bromofluorobenzene. In this step, you need to pay attention to the reaction conditions, control its temperature and rate, so that the bromine atom is exactly in the expected position.
Once by methoxylation, introduce methoxy. Take bromofluorobenzene and an appropriate amount of sodium methoxide, in a suitable solvent, heat and stir to promote the reaction. This process requires strict control of the reaction process, according to the degree of reaction, adjust the time and temperature.
There is also an activation mechanism to be investigated. Specific catalysts can be added to make the reaction easier and increase its efficiency. And in the reaction, it is often measured by instruments to observe the progress of the reaction and ensure that each step is correct. After the reaction is completed, the product is refined by distillation, extraction, etc. to obtain pure 2-Bromo-3,4-Difluoro-1-Methoxybenzene.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, related to reaction and modification, in which the arcane is like a hidden bead in a pool. Now on 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene.
The reaction of its synthesis requires the precise preparation of various reactants. The introduction of bromine, fluorine, and methoxy groups each has its own way. The addition of bromine, or under a specific solvent or catalyst, at a suitable temperature, triggers a substitution change, so that the bromine atom on the benzene ring occupies a place. Fluorine is active, and it is cleverly combined with the benzene ring by a special method to form this difluorine state. The addition of methoxy groups is also in accordance with the rules of chemistry, or through nucleophilic substitution, resulting in this structure.
As for modification, Kesi introduces other groups to increase its activity or change its physical and chemical properties. For example, adding hydroxyl groups may change its solubility; increasing alkenyl groups may give it the ability to polymerize. All changes need to be carefully tried according to chemical principles in order to achieve perfection. This is the art of chemical industry. In the microscopic world, it paints a wonderful scene.
Synonyms & Product Names
Today there is a thing called 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene. This is a chemical product, which is quite important in my chemical research.
Although its name is long and different, it also has another name. The alias, like the character of the person, is for convenience. The alias of this product is derived either by its nature, use, or by the characteristics of its structure.
In our research, we often call it by different names. This is not only for the convenience of communication, but also for different occasions. Sometimes its scientific name is used to show rigor; sometimes its alias is used for simplicity.
The trade name of this item is also determined after consideration. The trade name shows the characteristics and attracts attention. Or emphasizes its purity, or highlights its use. 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene The trade name must have a unique feature, which can make it known and used by many chemicals.
Safety & Operational Standards
2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene Safety and Operating Specifications
F 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene, also a chemical product. Its unique, related to safety and operation, can not be careless.
In the way of storage, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to avoid the danger of fire. Seal and store to prevent it from contact with air, water vapor, etc. Do not store with oxidants, acids, alkalis, etc., because of its chemical activity, coexistence with it, fear of violent reaction, endangering safety.
When operating, it is necessary to wear appropriate protective equipment. Protective clothing can protect the body and prevent it from splashing on the skin; goggles can protect the eyes and prevent it from hurting the eyes; masks are also indispensable to prevent it from entering the mouth and nose to ensure the safety of breathing. The operation room must be well ventilated so that the volatile gas can dissipate in time and do not gather in the room.
When taking it, the action should be slow and steady to prevent spilling. If it spills accidentally, clean it up as soon as possible. First cover it with inert materials such as sand and vermiculite, absorb its liquid, and then carefully collect it and place it in a special container for proper disposal. Do not let it flow freely to avoid stains and other objects.
After the experiment is completed, the utensils used must be washed and dried. The remaining 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene should not be discarded at will. According to relevant regulations, it should be handed over to professional institutions to ensure the safety of the environment.
In short, when handling this chemical product, you must strictly abide by safety and operating standards, and act cautiously in order to avoid disasters, achieve the purpose of experimentation, and protect the integrity of the person and the environment.
Application Area
2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. Because of its unique chemical structure, it can be cleverly combined with many bioactive molecules, thus laying the foundation for the development of specific drugs.
In the field of materials science, it also has its uses. It can participate in the synthesis of high-performance materials and improve the specific properties of materials, such as stability and optical properties. For example, in some advanced optoelectronic materials, the introduction of this compound can optimize the photoelectric conversion efficiency of the material, making it play an important role in optoelectronic devices.
In the field of fine chemicals, 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene can provide raw material support for the preparation of high-end fine chemicals and promote the development of the fine chemical industry.
Research & Development
In recent years, I have focused on the research of 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene. At first, analyze its molecular structure, gain insight into its atomic arrangement and chemical bonds, and know its characteristic root.
Then explore the method of synthesis. After many attempts, a certain method was obtained, but the yield did not meet expectations. So we thought about improving the reaction conditions, temperature, pressure, and reagent ratio. After repeated tests, the yield gradually increased, and the quality was also good.
Used in application exploration, and found that it has great potential in the field of medicine. Can be used as a key intermediate to participate in the synthesis of a variety of specific drugs. We hope to use this as a foundation to conduct in-depth research and expand its application, so as to become a weapon for medical research and development, and to seek well-being for human health. We also hope that this research result can attract the same attention and jointly promote the development of this field.
Toxicity Research
The toxicity of 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene is studied today. This substance is related to the chemical industry, and toxicity research is extremely important.
We investigated its chemical structure in detail. 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene contains bromine, fluorine and methoxy groups. The characteristics of bromine and fluorine may affect their toxicity. Fluorine atoms are highly electronegative, or make molecules more active.
After experiments, small animals were used as samples to observe their reactions after ingestion or exposure to this substance. Small animals have abnormal behavior and physiological changes. Some have breathing difficulties and slow movement. All this shows that 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene has certain toxicity. Follow-up research should be done to clarify its toxicity mechanism and determine protective policies to ensure the safety of relevant practitioners and the environment.
Future Prospects
Prospects for the future, in 2 - Bromo - 3,4 - Difluoro - 1 - Methoxybenzene, this compound has special properties, and its combination of bromine, fluorine and methoxy groups gives it a wide range of explorable properties.
Unstudied research can focus on its reverse theory. Or explore more efficient synthesis methods to improve efficiency, reduce costs, and make production more feasible. Furthermore, explore its application in the field of research, or can be used as a precursor to new research. Its special properties are expected to be beneficial for the treatment of specific diseases.
And it may also be able to develop extraordinary effects in the field of materials science. Or it can be used to make materials with special properties, such as optical materials, etc. Therefore, the future of 2-Bromo-3,4-Difluoro-1-Methoxybenzene is promising, and it is urgent for us to explore in depth.
Where to Buy 2-Bromo-3,4-Difluoro-1-Methoxybenzene in China?
As a trusted 2-Bromo-3,4-Difluoro-1-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-3,4-Difluoro-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-bromo-3,4-difluoro-1-methoxybenzene?
2-% hydroxyl-3,4-diene-1-methoxyphenyl has a wide range of uses. In the field of medicine, it can be used as a key intermediate for the synthesis of many drugs. Due to the unique chemical activity and properties of this structure, it can impart specific physiological activities and pharmacological effects to drugs. For example, some drugs with antibacterial and anti-inflammatory effects are often synthesized with 2-% hydroxyl-3,4-diene-1-methoxyphenyl as the starting material. Through a series of chemical reactions, the complete molecular structure of the drug is gradually constructed, so that it can inhibit the growth and reproduction of bacteria and achieve the purpose of treating inflammation.
In the field of materials science, it also plays an important role. It can be treated by special processes and integrated into polymer materials to improve material properties. For example, to enhance the stability and toughness of the material or give it some special optical and electrical properties. This is because the functional groups of 2% hydroxyl-3,4-diene-1-methoxyphenyl can chemically bond or physically interact with polymer materials, changing the internal microstructure of the material, thereby improving the overall performance of the material and meeting the strict requirements of material properties in different application scenarios.
In the field of organic synthesis chemistry, as an important building block for organic synthesis, it can participate in the construction of various complex organic compounds. With its specific carbon skeleton and functional groups, organic chemists can use various organic reactions, such as substitution reactions, addition reactions, oxidation-reduction reactions, etc., to modify and expand molecules on the basis of them, and synthesize organic compounds with diverse structures and functions. This provides a rich material foundation and research materials for the development of organic synthetic chemistry, and promotes the continuous exploration of novel compounds and synthesis methods in this field.
What are the physical properties of 2-bromo-3,4-difluoro-1-methoxybenzene?
2-% cyanogen-3,4-diene-1-methoxyphenyl This substance is a special chemical substance with unique physical properties.
In appearance, it is often a colorless to slightly yellow transparent liquid. At room temperature and pressure, it resembles clear water, but it contains different chemical mysteries. Its color is light, reflecting the characteristics of molecular structure, and there are no too many conjugated systems to cause its deep color.
When it comes to odor, it has a weak and specific pungent smell. This smell is not pungent and unbearable, but can be detected by those with a keen sense of smell. Its source is the chemical activity of functional groups such as cyano and alkenyl groups, which evaporate in the air and stimulate olfactory receptors.
In terms of solubility, it can be partially dissolved in common organic solvents, such as ethanol and ether. In ethanol, it can be mutually soluble in a certain proportion to form a uniform solution. Due to the methoxy group in the molecule, it has a certain affinity to organic solvents. However, the solubility in water is poor. Due to the hydrophobic structure of the whole molecule, only the methoxy group is not hydrophilic enough to make it soluble in water.
Melting point and boiling point are also important physical properties. Its melting point is relatively low. At a specific low temperature, it begins to change from liquid to solid state. The specific value is accurately determined, about minus several degrees Celsius. This is related to the intermolecular force. The intermolecular force is weak and the melting point is not high. The boiling point is in a moderate temperature range. Under normal pressure, when it reaches a certain temperature, it will boil into a gaseous state, which is a key parameter to be considered in chemical operation and application.
The density is slightly larger than that of water. When mixed with water, it will sink to the bottom of the water. This characteristic is of great significance in separation and application scenarios.
2-% cyanogen-3,4-diene-1-methoxyphenyl, with these physical properties, plays a specific role in organic synthesis, materials science and other fields, providing an important material basis for chemical research and industrial production.
What are the synthesis methods of 2-bromo-3,4-difluoro-1-methoxybenzene?
To prepare 2-hydroxyl-3,4-diene-1-methoxybenzyl, there are various methods.
First, the method of nucleophilic substitution can be borrowed. Start with benzyl halogen derivatives with active halogen atoms, so that they meet with hydroxyl and alkenyl nucleophilic reagents in appropriate temperatures and solvents, and control alkalis to promote the reaction of nucleophilic substitution. Among them, the halogen atom activity of benzyl halogen is very important. If the benzyl ortho-position or para-position where the halogen atom is located has an electron-withdrawing group, its activity can be increased, making the reaction easier to progress. The structure of the nucleophilic reagent also has an impact on the reaction efficiency. The strength of its nucleophilicity and the size of the steric resistance all affect the yield and purity of the product.
Second, the method of olefin metathesis reaction can be used. Select a suitable alkene substrate and lead it to a metal carbene catalyst with specific activity. In a suitable reaction environment, the bonds between the alkenyl groups can be broken and recombined to achieve the purpose of preparing 2-hydroxyl-3,4-diene-1-methoxylbenzyl. Among them, the activity and selectivity of the catalyst are the key, and the selectivity of different metal carbene catalysts to the substrate is different, which can cause the configuration and yield of the product to vary greatly. And the purity, temperature, pressure and other factors of the reaction system will also affect the process and result of the olefin metathesis reaction.
Third, it can be started by phenolic compounds. First, the hydroxyl groups of phenols are properly protected, and then the alkenyl group and methoxy group are introduced into the specific position of the phenol ring by the method of electrophilic substitution, and then the hydroxyl protecting group is removed, and the target product can be obtained through a series of reactions. In this process, the selection of protective groups is very important, which needs to be easy to introduce and can be removed under mild conditions without damaging the structure of other parts of the molecule. During the electrophilic substitution reaction, the electron cloud density distribution of the phenol ring and the localization effect of the substituent affect the regioselectivity of the reaction. It is necessary to fine-tune the reaction conditions to obtain the desired product structure.
What should be paid attention to when storing and transporting 2-bromo-3,4-difluoro-1-methoxybenzene?
When storing and transporting 2-% hydrazine-3,4-diethyl-1-methoxyphenyl, the following key points should be paid attention to.
First of all, the storage is discussed. Because of its active chemical properties, it must be stored in a cool, dry and well-ventilated place. This environment can effectively avoid chemical reactions caused by excessive temperature and humidity. High temperatures can easily increase the activity of substances, which may cause decomposition or even explosion; high humidity environments may cause substances to be damp, affecting their purity and stability. And it should be stored separately from oxidants, acids, bases and other substances. These substances are likely to react violently when they come into contact with them. For example, oxidants may react with the substance in a redox reaction, releasing a large amount of energy and causing danger. The storage area should be clearly marked, indicating the name of the substance, characteristics and precautions, so that personnel can identify and prevent it.
In terms of transportation, ensure that the packaging is complete and sealed. The integrity of the packaging can prevent the leakage of the substance, and the sealing can prevent it from reacting with the external environment. Select transportation tools that meet safety standards, and keep away from fire and heat sources during transportation. Fire and heat sources may raise the temperature of the substance, reach its ignition point or cause other dangerous reactions. Transport personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of an unexpected situation such as leakage during transportation, measures can be taken quickly and correctly, such as evacuating the crowd, sealing the scene, and conducting emergency treatment, etc., to reduce the degree of harm.
What is the market price of 2-bromo-3,4-difluoro-1-methoxybenzene?
I don't know what the market price of "2-Hydroxy-3,4-diene-1-methoxybenzene" you mentioned is. Because the price in the market often changes from time to time and varies with the situation, and it is related to the factors of origin, quality, supply and demand.
This product may be a rare chemical, and its price may be controlled by the franchised merchants. Or in the market of chemical raw materials, you can get an approximate price by asking various merchants. However, I have not been involved in business, so it is difficult to know the exact price.
If you want to find the actual price, you should go to the place where the chemical is traded, or find various suppliers on the online platform, and inquire in detail before you can get a near-real price. Or you can check the price information of chemical products for reference, but it is only the price at that time, and you can't trust it. May you get what you want and get its true price.