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2-Bromo-1-Fluoro-4-Methoxybenzene

2-Bromo-1-Fluoro-4-Methoxybenzene

Hongda Chemical

Specifications

HS Code

583000

Chemical Formula C7H6BrFO
Molar Mass 205.024 g/mol
Appearance Colorless to light - yellow liquid
Boiling Point 202 - 204 °C
Density 1.56 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Flash Point 83 °C
Vapor Pressure Low (due to relatively high boiling point)
Purity Typically available in high purity (e.g., 97%+ in commercial products)
Odor Characteristic organic odor

As an accredited 2-Bromo-1-Fluoro-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - bromo - 1 - fluoro - 4 - methoxybenzene packaged in a sealed glass bottle.
Storage 2 - bromo - 1 - fluoro - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent vapor leakage. As it is a chemical, store it separately from oxidizing agents, reducing agents, and reactive substances to avoid potential chemical reactions.
Shipping 2 - bromo - 1 - fluoro - 4 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical transport regulations, ensuring proper handling to prevent leakage and maintain safety during transit.
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2-Bromo-1-Fluoro-4-Methoxybenzene 2-Bromo-1-Fluoro-4-Methoxybenzene
General Information
Historical Development
Ancient scholars have explored many chemical substances. Today there is 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene, and its birth has also undergone changes over time.
In the past, chemistry was not as prosperous as it is today, and researchers relied on tenacity and keen thinking. At first, everyone explored the field of organic synthesis and became more and more interested in halogenated aromatic ether compounds. Although the conditions were simple, the wise men worked tirelessly to study.
At some point, some intelligent people, after repeated experiments, adjusted the temperature and pressure of the reaction, and selected reagents, finally obtained the method of synthesizing 2-Bromo-1-Fluoro-4-Methoxybenzene. Since then, many scholars have optimized the process and improved the yield on this basis. This compound, due to its unique structure, has gradually become useful in the fields of medicine, materials and other fields, contributing to the development of later chemistry. It is the crystallization of the wisdom and hard work of predecessors.
Product Overview
There is now a substance called 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. Its shape is also an organic compound with an exquisite molecular structure. Looking at its formula, bromine (Bromo), fluorine (Fluoro) and methoxy (Methoxy) are cleverly connected to the benzene ring.
This compound has a wide range of uses in the field of organic synthesis. The activity of bromine atoms is considerable, which can lead to the reaction of nucleophilic substitution, so that other functional groups can be derived from the benzene ring. The entry of fluorine atoms increases its fat solubility, which can be used in the creation of medicines and pesticides, or can help molecules and targets to closely interlock and enhance activity. The methoxy group has the property of an electron conductor, which affects the electron cloud density of the benzene ring and affects the check point and rate of the reaction.
The preparation method needs to choose the appropriate raw materials and paths according to the principle of organic synthesis. Or from the benzene ring-containing initial material, through various reactions such as halogenation and methoxylation, and carefully adjust the conditions, this pure product can be obtained for scientific research and industrial use.
Physical & Chemical Properties
2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene is an organic compound. Its physical properties are mostly liquid at room temperature and have a special odor. Due to the atomic arrangement and chemical bond characteristics in the molecule, it has a unique volatility. In terms of chemical properties, due to the existence of bromine, fluorine and methoxy groups, it has various reactivity. Bromine atoms have high activity and can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine atoms are easily replaced to form new compounds. Fluorine atoms have large electronegativity, which affects the distribution of molecular electron clouds and enhances their stability. Methoxy groups are the power supply subgroups, which can increase the density of electron clouds in the benzene ring and make it prone to electrophilic substitution reactions. This compound is widely used in the field of organic synthesis and can be used as an intermediate to participate in the construction of a variety of complex organic molecules.
Technical Specifications & Labeling
Today there is a product called 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. The preparation process involves many technical specifications and labels (product parameters).
When preparing, the selection of raw materials needs to be precise. Bromide, fluoride and methoxy compounds are mixed in an orderly manner according to a specific ratio. The reaction device should be clean and suitable to ensure a smooth reaction. The temperature of the reaction should be stable in a certain range, or it should be controlled at tens of degrees Celsius, not high or low. The duration is also fixed, about two hours, to get the best effect.
Product identification (product parameters), related to purity, should reach more than 90%, the amount of impurities, must be strictly controlled to a minimum. Its properties should be a specific color state, or a colorless crystal, or a transparent liquid. When preparing this product, the technical specifications and identification (product parameters) should not be ignored.
Preparation Method
To prepare 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism. The raw materials should be taken from suitable compounds and carefully proportioned. The production process needs to choose a good method to make the reaction smooth.
The first step of the reaction is precise, from the mixing of the initial raw materials to the control of the reaction conditions at each stage, all need to be cautious. For example, the adjustment of temperature and pressure is related to the reaction rate and product purity.
The catalytic mechanism is also the key. The selection of an appropriate catalyst can promote the efficient progress of the reaction, reduce energy consumption and yield. In the reaction, the catalyst can reduce the activation energy of the reaction, speed molecular collision, and assist in the breaking and formation of chemical bonds. In this way, 2-Bromo-1-Fluoro-4-Methoxybenzene can be prepared according to this, and high-quality products can be obtained.
Chemical Reactions & Modifications
Recently, 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene has been studied. The reaction and modification of this compound are related to many things. In the past, the reaction method was limited, the yield was not high, and the properties were not perfect.
We want to change the method of reaction and explore new ways to increase its efficiency. Such as adjusting the temperature and pressure of the reaction, choosing the appropriate catalyst, hoping to promote the anterograde of the reaction, and increase the yield. And the time can change its properties to make it more useful in various domains.
Reaction and modification are important matters in the study of compounds. I must study diligently to find the best method of chemical application and modification of 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene, and contribute to the chemical industry.
Synonyms & Product Names
Today there is a thing called 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. This thing is of great significance in our chemical research.
Its synonymous name also exists. Due to the chemical naming rules, there are different perspectives and methods, resulting in synonymous names. As for the trade name, it also varies according to many factors such as business, use and market.
Although its synonymous name may be different from the trade name, it is essentially this thing. When we study, we must distinguish its different names in order to be accurate and not confused. This is a key thing in chemical research and practical application, and cannot be ignored.
Safety & Operational Standards
2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene Safety and Operation Specifications
Fu 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene, the product of the chemical is also, in the experiment and production, must follow the safety and operation specifications to keep it safe.
First words storage. This product should be placed in a cool, dry and well ventilated place. Avoid open flames and hot topics to prevent accidents. Its nature or phase with other substances, so it should be stored separately with oxidants, strong alkalis, etc., and must not be mixed to avoid disasters.
Times and operation. When operating, prepare protective gear. Wear protective clothing to prevent it from sticking to the body; wear goggles to protect your eyes; wear protective gloves to avoid touching it by hand. The place of operation must be well ventilated, so that the exhaust gas can be discharged quickly and does not gather in the room. If you take this product, use an adapter, take it according to the amount, and the action should be slow, so as not to spill.
If it is unfortunate to spill, dispose of it quickly. Shilling those who are unrelated to avoid it and set up warning signs. When a small amount is sprinkled, you can use sand, vermiculite, etc. to suck it up and collect it in a suitable place. When a large amount is sprinkled, contain it to prevent dispersion, and then clean it with appropriate methods. The collected things should not be discarded at will, and should be disposed of in accordance with regulations.
Furthermore, it is about contact. If the skin touches it, rinse quickly with plenty of water, followed by fine soap. If it enters the eye, rinse immediately with flowing water or normal saline, and seek medical treatment. If aspiration, quickly move to a fresh air place, keep breathing smooth, and apply artificial respiration if necessary, and seek medical attention. If taken by mistake, do not induce vomiting, seek medical attention immediately, and follow medical advice.
In short, all things in 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene must be done with caution, in accordance with safety and operating standards, in order to ensure personal safety, avoid accidents, and make scientific research and production go smoothly.
Application Area
2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene has a wide range of application fields. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many special drugs. According to ancient sayings, the unique structure of this compound is like the delicate cornerstone of medicinal stone refining, which helps doctors make a cure for diseases and diseases.
In the field of materials science, this substance also plays an important role. It can participate in the preparation of materials with special optoelectronic properties, as if it can give the material a unique "spirit", so that it can show extraordinary functions in optoelectronic devices.
Furthermore, in the field of fine chemicals, 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene can be used to synthesize various high-end fine chemicals, such as delicate fragrances, high-quality dyes, etc., just like adding colorful flowers to the chemical garden and enriching many aspects of people's lives.
Research & Development
Recently, in my research, I focused on the compound 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. This is a very critical raw material in organic synthesis and has unique chemical properties.
Initially explore its synthesis path, consult ancient books and regulations, learn from the methods of predecessors, and after many attempts and adjustments. In the study of reaction conditions, it is quite laborious, and the temperature, pressure, and ratio of reactants are all finely regulated. Every attempt is recorded in detail to obtain the best synthesis plan.
When synthesizing, the purity of raw materials and the monitoring of the reaction process are all crucial. If there is a slight difference, the product is not pure and does not meet expectations. After months of hard work, a stable synthesis method has been gradually obtained, and the purity and yield of the product have also become better.
Looking to the future, this compound may shine in the fields of medicine and materials. I should make unremitting efforts to explore its potential, hoping to contribute to the advancement of scientific research and the prosperity of industry.
Toxicity Research
Today, there is a substance called 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. In our chemical research, the detection of toxicity is the key.
The toxicity of this substance is related to the safety of the experimenter and the impact of the environment. We use caution and rigorous methods to explore its toxicity. After a series of experiments, observe its interaction with various substances and observe its changes in properties under different conditions.
However, the study of toxicity cannot be done overnight. Many factors, such as differences in concentration and duration of action, can cause differences in toxicity. We need to record the data in detail and analyze the results in order to clarify the law of its toxicity.
Although the road to research is long, we will be able to understand the mystery of the toxicity of 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene by upholding the spirit of science and unremitting research, and contribute to the progress of chemistry and the safety of mankind.
Future Prospects
Today there is a product called 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene. In the process of my chemical research, I am full of longing for the future development of this product.
Looking at its structure, bromine, fluorine and methoxy are cleverly connected, as if it contains endless mysteries for us to explore. In the future, it may emerge in the field of new materials. With its unique chemical properties, materials with outstanding performance can be produced for use in electronic components, which can greatly enhance their performance, or for special coatings to enhance the protective ability of materials.
In the process of pharmaceutical research and development, it may become a key intermediate. Based on it, through exquisite synthesis, new medicines with extraordinary curative effects have been produced, bringing good news to the sick.
I firmly believe that with time and in-depth research, 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene will surely shine, create new trends in various fields, and bring many surprises and changes to our lives. The future is bright.
Where to Buy 2-Bromo-1-Fluoro-4-Methoxybenzene in China?
As a trusted 2-Bromo-1-Fluoro-4-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-1-Fluoro-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-1-Fluoro-4-Methoxybenzene?
2-Bromo-1-fluoro-4-methoxybenzene is one of the organic compounds. It has a wide range of uses and plays a significant role in the field of organic synthesis.
Bearing the brunt, it can be used as an intermediate in pharmaceutical synthesis. In the preparation process of many drugs, this compound can be used as a key starting material. Through a series of organic reactions, such as nucleophilic substitution, coupling reactions, etc., it can be converted into complex molecular structures with specific pharmacological activities. For example, in the development of therapeutic drugs for specific diseases, based on 2-bromo-1-fluoro-4-methoxybenzene, through ingenious chemical modification and reaction steps, drug molecules with high affinity for disease-related targets can be constructed, thus achieving the purpose of treating diseases.
Furthermore, in the field of materials science, it also has its application. In the synthesis of certain functional materials, 2-bromo-1-fluoro-4-methoxybenzene can introduce special functional groups. These functional groups give the material unique physical and chemical properties, such as improving the conductivity, optical properties or thermal stability of the material. For example, in the preparation of new optoelectronic materials, its participation in the reaction can optimize the absorption and emission characteristics of the material to specific wavelengths of light, laying the foundation for the improvement of the performance of optoelectronic devices.
In addition, in the field of pesticide synthesis, it can often be seen. Through appropriate chemical reactions, it is converted into compounds with insecticidal, bactericidal or herbicidal activities. Its special chemical structure can act on specific physiological processes of pests, bacteria or weeds, so as to achieve the effect of control and help the smooth progress of agricultural production.
In conclusion, 2-bromo-1-fluoro-4-methoxybenzene plays an indispensable role in many fields such as medicine, materials and pesticides, and promotes the sustainable development and progress of related fields due to its unique chemical structure and reactivity.
What are the physical properties of 2-Bromo-1-Fluoro-4-Methoxybenzene?
2-Bromo-1-fluoro-4-methoxybenzene is an organic compound. Its physical properties are very important and are related to many chemical applications.
Looking at its properties, under normal temperature and pressure, this compound is mostly a colorless to pale yellow liquid. This color and state provide intuitive clues for the identification and identification of the substance. Because it is a liquid with good fluidity, it is easier to mix and disperse in various reaction systems, which can promote uniform and efficient chemical reactions.
When it comes to melting point and boiling point, the melting point value is very critical to define the conditions for the transition between solid and liquid states. However, the exact melting point data often fluctuates due to factors such as the purity of the compound. The boiling point is related to its gasification temperature. Under certain temperature conditions, 2-bromo-1-fluoro-4-methoxybenzene will be converted from liquid to gaseous. Knowing the boiling point is of great significance in chemical operations such as distillation and separation, so as to realize the effective separation and purification of this compound from other substances.
The density of 2-bromo-1-fluoro-4-methoxybenzene cannot be ignored. Its density is higher or lower than that of water, and this property plays a role in liquid-liquid separation operations. If the density is greater than that of water, it will be in the lower layer in the layered system; otherwise, it will be in the upper layer. With this difference, it can be separated by means of separation.
In terms of solubility, this compound may have good solubility in organic solvents such as ethanol and ether. This property makes it very useful in the field of organic synthesis. It can be used as a reactant or intermediate to build a suitable reaction environment with the help of organic solvents, which is conducive to the smooth development of chemical reactions. However, its solubility in water is not good, and this property also provides ideas for its separation and purification. It can be operated by taking advantage of the difference in solubility between water and organic solvents.
In addition, the volatility of 2-bromo-1-fluoro-4-methoxylbenzene is also an important physical property. Moderate volatility, so that in some reactions or application scenarios, it can participate in the reaction in the form of gas, or evaporate and escape the system under specific conditions. However, volatility also needs to be carefully controlled, because it involves issues such as storage stability and operational safety. When storing, it is necessary to choose a well-sealed container to prevent its volatilization loss and external environmental factors from interfering.
Overall, the physical properties of 2-bromo-1-fluoro-4-methoxybenzene, such as properties, melting point, density, solubility and volatility, are of great significance in chemical research, chemical production and related application fields, providing an important basis for its preparation, separation, storage and use.
What is the chemical synthesis method of 2-Bromo-1-Fluoro-4-Methoxybenzene?
To prepare 2-bromo-1-fluoro-4-methoxybenzene, you can follow the following method. Start with p-methoxyphenol as raw material, which is easy to obtain. First, the p-methoxyphenol is reacted with a halogenated reagent to introduce fluorine atoms. Commonly selected fluorine-containing reagents such as potassium fluoride, etc. are heated and stirred in a suitable solvent, such as dimethyl sulfoxide (DMSO), to promote the fluorine atom to replace the hydrogen of the hydroxyl group to generate 1-fluoro-4-methoxybenzene. This process requires attention to the reaction temperature and time. If the temperature is too high or the time is too long, side reactions may occur, which will affect the purity and yield of the product.
After 1-fluoro-4-methoxybenzene is obtained, the bromination reaction is carried out. Liquid bromine is used as a brominating agent, with a suitable catalyst, such as iron powder or iron tribromide. In a low temperature environment, such as 0-5 ° C, slowly add liquid bromine to the reaction system of 1-fluoro-4-methoxybenzene dropwise. Because the bromination reaction is active, low temperature can help control the reaction rate and reduce the generation of polybromination by-products. Add dropwise, gradually raise to room temperature, and continue to stir to complete the reaction.
The reaction is over, and the product is separated and purified. First, extract with an organic solvent, such as dichloromethane, and separate the organic phase. The organic phase is then washed with dilute alkali solution and water in sequence to remove unreacted raw materials and impurities. After the organic phase is dried with anhydrous sodium sulfate, it is distilled under reduced pressure to obtain pure 2-bromo-1-fluoro-4-methoxybenzene.
The whole synthesis process, the selection of raw materials, the control of reaction conditions, and the separation and purification methods are all key, and careful operation is required to obtain high-purity target products.
What are the precautions in storage and transportation of 2-Bromo-1-Fluoro-4-Methoxybenzene?
2-Bromo-1-fluoro-4-methoxybenzene is an organic compound. When storing and transporting, many things need to be paid attention to.
First storage. Because of its chemical activity, it should be placed in a cool, dry and well-ventilated place. If the environment is humid, moisture or reactions such as hydrolysis will damage its quality. Temperature is also critical. Excessive temperature may cause its volatilization to accelerate, or even trigger chemical reactions and cause it to deteriorate. Therefore, it is generally suitable to store in a low temperature environment, but it cannot reach its freezing point, and it is inconvenient to use due to anti-crystallization. The storage container is selected to be corrosion-resistant, and the glass material is usually preferred. Because of its stable chemical properties, it is not easy to react with the compound. At the same time, the container must be sealed to prevent contact with the air. Oxygen in the air may cause oxidation, and gases such as carbon dioxide may participate in chemical reactions.
Further transportation. During transportation, the compound must be properly packaged to prevent damage to the container due to collision and vibration. Commonly used buffer materials such as foam plastics, cotton, etc. wrap containers. Transportation vehicles also need to maintain a suitable temperature and humidity environment, and avoid direct sunlight. Transport personnel should be familiar with the characteristics of the compound and emergency treatment methods to prevent accidents. If the container leaks during transportation, personnel should be evacuated immediately, the scene should be isolated, and corresponding treatment measures should be taken according to its characteristics. If the leakage is adsorbed with inert materials such as sand, it should be properly disposed of.
In addition, whether it is stored or transported, it must be operated in strict accordance with relevant regulations and standards. Labels clearly indicate the compound name, properties, hazards and other information for personnel to identify and handle. In this way, the safety and stability of 2-bromo-1-fluoro-4-methoxybenzene during storage and transportation can be ensured.
What is the market price range for 2-Bromo-1-Fluoro-4-Methoxybenzene?
Wuguanfu 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene The price of this product in the market is not easy to determine. The range of its price is often changed due to various reasons.
First, it is related to the difficulty of preparation. If the preparation method is cumbersome, rare raw materials are required, and the process is difficult and labor-intensive, the price will be high. On the contrary, if the preparation method is simple and the raw materials are easy to obtain, the price may be slightly flat.
Second, it depends on the supply and demand of the market. If there are many people who want it, but there are few who supply it, the so-called thing is rare and expensive, and its price is high. If the market is flooded and the supply exceeds the demand, the price will inevitably decline.
Third, the origin and transportation are also involved. If it is shipped from a distance, the freight will be added, and the price will increase. If it is produced in the near land, the freight will be saved, and the price may be reduced.
Fourth, the good quality will also affect the price. Those with high quality often have higher prices than ordinary ones.
Overall, today, the market price of 2 - Bromo - 1 - Fluoro - 4 - Methoxybenzene ranges from tens to hundreds of yuan per gram. However, this is only an approximate number. The market conditions are ever-changing, and it is difficult to determine its exact price. If you want to know the details, you must inquire carefully from chemical raw material companies, traders, etc.