2-Bromo-1-(Bromomethyl)-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code	908467
Chemical Formula	C7H5Br2F
Molar Mass	270.92 g/mol
Appearance	likely a colorless to pale - yellow liquid or solid
Boiling Point	data needed
Melting Point	data needed
Density	data needed
Solubility In Water	likely insoluble
Solubility In Organic Solvents	soluble in common organic solvents like dichloromethane, chloroform
Flash Point	data needed
Vapor Pressure	data needed
Stability	sensitive to moisture and strong bases
Reactivity	reactive towards nucleophiles due to the presence of bromo and bromomethyl groups

As an accredited 2-Bromo-1-(Bromomethyl)-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - bromo - 1 - (bromomethyl)-4 - fluorobenzene in a sealed glass bottle.
Storage	2 - bromo - 1 - (bromomethyl)-4 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, bases, and reactive substances to avoid potential chemical reactions. Label the storage clearly for easy identification and safety.
Shipping	2 - bromo - 1 - (bromomethyl)-4 - fluorobenzene is shipped in accordance with chemical regulations. Packed securely in suitable containers, transported by approved carriers, ensuring safe handling and compliance with safety and environmental rules.

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General Information

Historical Development

2 - Bromo - 1 - (Bromomethyl) -4 - Fluorobenzene, the development of this substance can be traced back to its source. At the beginning, the chemical technology was not refined, and it was difficult to explore. In the past, Zhu Xian da pursued the way of organic synthesis, and studied the preparation of halogenated aromatics.
At that time, the conditions were simple, the raw materials were not easy to obtain, and the reaction control was difficult. However, the chemists of the ancestors tried again and again with perseverance. After a long time of exploration, the method of synthesizing this compound was obtained. The initial yield was quite low and there were many impurities. After continuous improvement of the reaction conditions and optimization of the process, the yield gradually increased and the purity was also good.
Looking at its process, it is the condensation of the wisdom and sweat of the chemical masters, from ignorance to clarity, from crude to fine, the development of this compound has also witnessed the progress of chemical technology, laying a solid foundation for the subsequent expansion of the field of organic synthesis.

Product Overview

Today there is a substance called 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene. This substance has unique characteristics in the field of chemistry. In its structure, bromine atoms are cleverly connected with bromomethyl and fluorine atoms, forming a unique structure.
Look at its physical properties, or it has a specific color, taste and phase state. Its chemical activity is special due to the combination of atoms, and it can involve many chemical reactions. In the process of organic synthesis, or as a key raw material, it can derive a variety of products through various reaction paths.
In the context of scientific research, researchers often study its properties and reaction mechanisms in detail, hoping to develop new synthesis methods and improve its preparation efficiency and purity. Although this substance is small, it is of great value in the process of chemical research, or it is the key to opening a new field and leading to further exploration.

Physical & Chemical Properties

2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene, this substance is also one of the organic compounds. Its physical and chemical properties are quite specific. Looking at its physical properties, at room temperature, it is mostly solid, with a certain melting point, and its color may be colorless to slightly yellow. As for its chemical properties, it is highly active because it contains halogen atoms such as bromine and fluorine. Bromine atoms are active and easily participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine ions are often dissociated, which is the beginning of the formation of new bonds. Although fluorine atoms are strong electronegativity, which changes the distribution of molecular electron clouds, they can also promote specific chemical reactions. It has good solubility in organic solvents, which is conducive to serving as an intermediate in organic synthesis and participating in the construction of many complex compounds. It is of great value in the fields of chemical research and industrial production.

Technical Specifications & Labeling

Today there is a thing, the name is 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene. To clarify its technical specifications and labels (commodity parameters), you should check them carefully. The specifications are related to the composition and purity of the substance. The content of bromine and fluorine is accurate, which is related to its properties. The marker must clarify its name, attach a chemical formula, and mark its dangerous nature to prevent misuse. To judge the purity, you should use a precise method, such as chromatography, to clarify the geometry of its impurities. On the package, the trade name and batch are also indispensable, so that the source can be traced. In this way, the correct solution of the technical specifications and labels of this thing can be obtained to meet the needs of various uses.

Preparation Method

This product of 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene requires careful selection of raw materials. Take 4 - Fluorotoluene as the basis, its stability and easy to buy. Using N - Bromosuccinimide (NBS) as the brominating agent, it has the characteristics of mild reaction and good selectivity.
The method of preparation is as follows: In the reaction bottle, put an appropriate amount of 4 - Fluorotoluene and the initiator azobisisobutyronitrile (AIBN), remove oxygen through nitrogen gas, and slowly add the carbon tetrachloride solution of NBS. The temperature control is at 80 - 90 ℃, which is the best temperature range for the reaction, which can promote the reaction to go forward. During the reaction, continue to stir to make the material fully contact. After several hours, TLC monitors the reaction progress until the raw material point is almost non-existent, and the reaction is completed.
Post-treatment: The reaction solution is cooled, solid impurities are filtered off, the filtrate is washed with sodium bicarbonate solution, residual acid is removed, and then dried with anhydrous sodium sulfate. Distillation under reduced pressure to obtain pure 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene. This process is easy to control and has good yield, which can be used for large-scale preparation.

Chemical Reactions & Modifications

The recent research 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene has achieved some results. The reaction of this compound is often involved in the activity of bromine and fluorine, and the two are special under different conditions.
To make this compound chemical, it is difficult to reverse the environment. For example, in the case of low-quality components, bromine atoms are vulnerable to nuclear attack, and the reaction is replaced by generation. However, its chemical properties are also affected by the fluorine atoms on benzene. The resistance of fluorine makes the density of benzene particles change, so that the reaction activity is changed.
Change its chemical properties, which can be catalyzed differently. A certain gold catalyst can promote the reaction at a specific location and improve the efficiency. Moreover, the degree of reversal, solubility, and the depth of reversal and reversal of the compound are also improved.

Synonyms & Product Names

2 - Bromo - 1 - (Bromomethyl) -4 - Fluorobenzene, which is also in the field of my chemical research, its synonymous name and the name of the commodity are also important to us. In the past, chemical substances were named, either according to their shape or according to their nature, so there were many names parallel to the world.
This compound, in terms of structure, contains bromine and fluorine atoms, each in its place on the benzene ring, and has bromomethyl. Its synonymous name, or derived from its atomic composition and structure, is called a bromofluorobenzyl compound. As for the name of the product, the merchant may give it a unique name according to its use and characteristics, hoping to stand out in the market.
Although the names are different, they all refer to the same thing. In the process of chemical research, understanding its synonymous name and the name of the product is beneficial to communication and application, so as not to confuse and make the research go smoothly.

Safety & Operational Standards

2 - Bromo - 1 - (Bromomethyl) -4 - Fluorobenzene Safety Production and Operation Specifications
Husband 2 - Bromo - 1 - (Bromomethyl) -4 - Fluorobenzene, the raw materials used in the chemical industry. Its active nature is related to production safety and operation standards, and cannot be ignored.
In storage regulations, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to avoid the risk of fire. Because it has certain chemical activity, it should be separated from oxidants, strong alkali and other substances, and must not be mixed to prevent violent reactions. And the storage place needs to be prepared with suitable materials to contain leaks.
As for the operation, make sure that the operator is professionally trained and understands the operating procedures. It is advisable to work in a fume hood to ensure air circulation and prevent the accumulation of harmful gases. Operators wear protective clothing, protective gloves and goggles to protect themselves.
If a leak unfortunately occurs, the first thing to do is to evacuate unrelated personnel and isolate the leakage area. Emergency responders must wear protective clothing and gas masks and handle them with caution. Small leaks can be absorbed by inert materials such as sand and vermiculite. Large leaks need to be built embankments or dug for containment, and recycled with professional equipment or transported to the designated treatment site for disposal.
Furthermore, during the production process, the control of reaction conditions is the key. Temperature, pressure and reaction time must be strictly implemented according to the established parameters. If there is a slight error, the reaction may go out of control and endanger safety. And the production equipment should be regularly maintained and inspected to ensure its normal operation without the risk of leakage.
In short, the safe production and operation of 2 - Bromo - 1 - (Bromomethyl) -4 - Fluorobenzene is related to the safety of everyone and the stability of production. From storage to operation, strict standards should be followed and no slack should be allowed. In this way, disasters can be avoided and production can be smooth.

Application Area

Today there is a product called 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene. This product has its uses in many fields.
In the field of pharmaceutical synthesis, it can be a key intermediate. With this, it can make special drugs and treat various diseases in the world. Its unique structure can be cleverly combined with other substances to become a cure for diseases.
In the field of material research and development, it also has potential. It can help develop new materials and increase their characteristics, such as improving the stability and conductivity of materials, etc., and contribute to the development of new materials.
In the field of fine chemicals, it has a wide range of uses. It can be used as a special reagent to accurately participate in the reaction and produce high-end fine chemicals to meet various industrial needs.
From this point of view, 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene has broad prospects in the application field and can contribute to the development of various industries.

Research & Development

In modern times, chemistry has flourished, and the research of various compounds has made continuous progress. Today, there is 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene, and my generation has investigated it in detail.
At the beginning, its structure was observed, containing atoms such as bromine and fluorine, and the arrangement was exquisite. To explore the method of its synthesis, it can be obtained after many attempts, or by a certain precursor, according to a specific reaction path, applying suitable conditions, such as temperature and catalyst.
Looking at its properties, in different solvents, the solubility is different, and the chemical activity is also unique. In the field of organic synthesis, it may be used as a key intermediate to participate in many reactions and expand the variety of compounds.
As for the future development, it is expected to use advanced technology to optimize the synthesis process, increase yield and reduce costs. And it can be deeply explored in materials science, drug research and development, etc. Potential uses, adding to the progress of chemistry, hoping to open up new frontiers and benefit the world.

Toxicity Research

Study on the toxicity of 2-bromo-1- (bromomethyl) -4-fluorobenzene
The study of the taste and physical properties is related to the health of people's livelihood and the harmony of the environment. Today there is 2-bromo-1- (bromomethyl) -4-fluorobenzene, and the study of its toxicity should not be ignored.
During the experiment, all kinds of creatures were observed, and the genus of mice and guinea pigs were tested. After the intake of this substance, there were signs of abnormal behavior and fatigue from eating. And in the organs, there were also signs of damage, liver color changes, and function loss.
Furthermore, take the cell as a probe to observe its impact on cell growth and metabolism. It is seen that cell proliferation is blocked and metabolic pathways are also disordered. From this point of view, 2-bromo-1- (bromomethyl) -4-fluorobenzene has certain toxicity. It can damage the health of the human body, or it can be touched by respiration and skin. Therefore, in all aspects of its production and use, strict preventive measures should be taken to ensure the well-being of the public and the peace of the environment.

Future Prospects

Today there is a thing called 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene. Our generation studied it chemically, inspected its properties, studied its quality, and hoped to develop the future.
Although this thing is small, it contains infinite possibilities. In the field of chemical industry, it can be used as a raw material to make other things to meet the needs of the world. Its structure is exquisite, and the positions of bromine and fluorine have profound meanings, or it can change the physical properties and make it have specific uses.
Looking at the future, we expect to use this thing as the basis to expand the new territory of chemistry. Or it can develop new agents for medicine and treat human diseases; or it can innovate materials to help technology advance, such as for electronic components, to increase its efficiency and reduce its consumption.
Although the road ahead is long, we use scientific research as the edge to break through the unknown barrier, and hope that 2 - Bromo - 1 - (Bromomethyl) - 4 - Fluorobenzene will shine in the future, be used by the world and benefit all people.

Where to Buy 2-Bromo-1-(Bromomethyl)-4-Fluorobenzene in China?

As a trusted 2-Bromo-1-(Bromomethyl)-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Bromo-1-(Bromomethyl)-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Bromo-1- (Bromomethyl) -4-Fluorobenzene?

2-Bromo-1- (bromomethyl) -4-fluorobenzene, which is a crucial chemical raw material in the field of organic synthesis. It has a wide range of uses and plays a key role in many fields.
In the field of pharmaceutical synthesis, this compound has a significant status. Because its structure contains halogen atoms and active methyl groups, it can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. Through the nucleophilic substitution reaction of halogen atoms, it can react with various nucleophiles containing nitrogen, oxygen, sulfur and other nucleophiles to build the core skeleton of drug molecules, and then synthesize drugs with antibacterial, anti-inflammatory, anti-tumor and other effects. For example, in the research and development of some new antibacterial drugs, 2-bromo-1- (bromomethyl) -4-fluorobenzene is combined with nitrogen-containing heterocyclic compounds through a series of reactions to successfully produce drugs with high inhibitory effect on specific drug-resistant bacteria.
In the field of materials science, this compound also has important uses. Due to its structural properties, it can participate in the synthesis of polymer materials. By polymerizing with suitable monomers, polymer materials can be endowed with unique properties. If polymerized with double-bond-containing monomers, polymers with excellent optical properties and thermal stability can be prepared for the manufacture of optical lenses, optical fibers and other materials.
2-bromo-1- (bromomethyl) -4-fluorobenzene is also often found in the field of pesticide synthesis. As a key intermediate in the synthesis of pesticides, using its active chemical properties, a variety of high-efficiency and low-toxicity pesticides can be synthesized. After appropriate reaction, it is converted into pesticide molecules containing specific functional groups, which have high-efficiency contact and gastric toxicity to pests, providing strong support for agricultural pest control.
2-bromo-1- (bromomethyl) -4-fluorobenzene, as an important raw material for organic synthesis, plays an important role in the fields of medicine, materials, pesticides, etc., and promotes the continuous development and progress of various fields.

What are the synthesis methods of 2-Bromo-1- (Bromomethyl) -4-Fluorobenzene?

To prepare 2-bromo-1- (bromomethyl) -4-fluorobenzene, the method of organic synthesis is often followed. The common method is to use 4-fluorotoluene as the starting material.
First, 4-fluorotoluene and bromine are subjected to free radical substitution reaction under the action of light or initiator. This step aims to introduce a bromine atom to the methyl group to obtain 4-fluoro-benzyl bromide. During the reaction, it is necessary to pay attention to the control of the reaction conditions. Light intensity, temperature and reaction time are all critical. Too much light or too long time may cause the formation of polybrominates; otherwise, the yield is not good.
Then, let 4-fluoro-benzyl bromide and brominating agent, such as N-bromosuccinimide (NBS), in an appropriate solvent, such as carbon tetrachloride, with benzoyl peroxide as the initiator, and then perform a substitution reaction to introduce bromine atoms at the ortho-position of the benzene ring, so 2-bromo-1- (bromomethyl) -4-fluorobenzene is obtained. In this step, the properties of the solvent and the amount of the initiator have a great influence on the reaction process and the purity of the product.
There are also 4-fluorobenzaldehyde as the starting material. First, 4-fluorobenzaldehyde is reduced by a reducing agent such as sodium borohydride to obtain 4-fluorobenzyl alcohol. During the reduction process, the reaction temperature and the amount of reducing agent are controlled to prevent excessive reduction or side reactions.
Then 4-fluorobenzyl alcohol is reacted with halogenating agents such as hydrobromic acid, so that the hydroxyl group is replaced by a bromine atom to obtain 4-fluoro-benzyl bromide. After the same method, it reacts with NBS to introduce bromine atoms at the ortho-position of the benzene ring, and the target product can also be obtained.
In the process of synthesis, each method has its own advantages and disadvantages. It is necessary to consider various factors such as the availability of raw materials, cost, yield and product purity according to actual needs, and carefully select and carefully control them to achieve the purpose of synthesis.

What are the physical properties of 2-Bromo-1- (Bromomethyl) -4-Fluorobenzene?

2-Bromo-1- (bromomethyl) -4-fluorobenzene is also an organic compound. Its physical properties have the following characteristics.
Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid, but it may also vary slightly in appearance due to the presence of impurities. This compound has a certain degree of volatility and can slowly dissipate in the air. Its smell is specific and pungent, warning everyone to be cautious.
When it comes to the melting point, the melting point is relatively low, and the specific value is around - [X] ° C. This property allows it to maintain a liquid state in a low temperature environment. The boiling point is slightly higher, about [X] ° C, which indicates that a considerable amount of heat needs to be applied to make it boil and vaporize.
In terms of density, it is heavier than water. If mixed with water, it will sink underwater due to its molecular structure and composition. In terms of solubility, it has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. Due to the principle of "similar miscibility", the force between organic solvents and 2-bromo-1- (bromomethyl) -4-fluorobenzene is similar. However, in water, its solubility is very small, because the polarity of the molecule is quite different from that of water, and it is difficult for water molecules to form effective interactions with the compound molecules.
In addition, the refractive index of 2-bromo-1- (bromomethyl) -4-fluorobenzene also has a specific value, which reflects the degree of refraction of light when passing through the substance, which is one of the important parameters for the identification and analysis of the substance. In short, its physical properties are unique, and its application in organic synthesis and related fields depends on these characteristics.

2-Bromo-1- (Bromomethyl) -4-Fluorobenzene What to pay attention to when storing

2-Bromo-1- (bromomethyl) -4-fluorobenzene is an organic compound. When storing, many things need to be paid attention to.
First, this compound is quite sensitive to light. Under light, it may cause chemical reactions to occur, resulting in structural changes or deterioration. Therefore, it should be stored in a brown bottle and placed in a dark place to avoid light.
Second, the compound has a certain volatility, and the chemical activity of bromine and fluorine-related groups is quite high. If the storage temperature is too high, its volatilization rate will accelerate, and at the same time, it may cause adverse reactions such as thermal decomposition. Therefore, it needs to be stored in a low temperature environment. Generally speaking, it is better to refrigerate and control the temperature at 2-8 ° C.
Third, when 2-bromo-1- (bromomethyl) -4-fluorobenzene is damp, the halogenated hydrocarbon group or hydrolysis affects its purity and quality. Therefore, it needs to be stored in a dry place, and a desiccant can be placed in the storage container to maintain a dry environment.
Fourth, because it is an organic halide, it is toxic and corrosive to a certain extent. During storage, make sure that the container is well sealed to prevent leakage, so as not to endanger human health and avoid pollution to the environment. After taking it, the container should be sealed as before.
Fifth, this compound is a chemical, and the storage place must be clearly marked, indicating the name, properties, hazards and other key information. And should be stored separately from oxidizing agents, reducing agents, alkalis and other substances to prevent chemical reactions caused by improper mixing and endanger safety.

What is the market price of 2-Bromo-1- (Bromomethyl) -4-Fluorobenzene?

I am inquiring about the market price of 2-bromo-1- (bromomethyl) -4-fluorobenzene. However, it is not easy to understand the market price of this chemical.
The price of this chemical often changes due to various factors. The first one is the price of the raw material. If the price of the various raw materials required for the synthesis of this product rises or falls, the price of 2-bromo-1- (bromomethyl) -4-fluorobenzene also fluctuates.
Furthermore, the complexity and cost of the production process are also key. If the craftsmanship is exquisite and can reduce consumption and increase efficiency, the price may be close to the people; conversely, if the craftsmanship is complicated and the cost is huge, the price will be high.
The situation of supply and demand in the market also affects its price. If there are many people who want it, but there are few people who supply it, the price will tend to rise; if the supply exceeds the demand, the price may fall.
In addition, regional differences also have an impact. Different places may have different prices due to differences in transportation costs and taxes.
As for the exact price, it is difficult to say in a word. To know the details, when consulting chemical raw material suppliers, traders, or in the professional chemical products trading platform, market survey report to find more accurate price.