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2-Bromo-1,4-Difluorobenzene

2-Bromo-1,4-Difluorobenzene

Hongda Chemical

Specifications

HS Code

100980

Chemical Formula C6H3BrF2
Molar Mass 193.009 g/mol
Appearance Liquid
Boiling Point 156 - 157 °C
Density 1.715 g/mL at 25 °C
Solubility In Water Insoluble
Flash Point 56 °C
Refractive Index 1.513

As an accredited 2-Bromo-1,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2 - bromo - 1,4 - difluorobenzene in a sealed glass bottle.
Storage 2 - bromo - 1,4 - difluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions. Label the storage container clearly with relevant hazard information.
Shipping 2 - bromo - 1,4 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. Compliance with regulations for hazardous chemicals is ensured. Shipment may be via ground or air, depending on quantity and destination, with proper safety documentation.
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2-Bromo-1,4-Difluorobenzene 2-Bromo-1,4-Difluorobenzene
General Information
Historical Development
"The History of Dibromo-1 and Tetrafluorobenzene"
Dibromo-1 and tetrafluorobenzene are chemical things. Its beginning depends on the research of scholars. In the past, the field of chemistry was gradually emerging, and everyone wanted to explore the properties of things and find ways to change.
At the beginning, researchers looked for its traces in the micro-end, although the equipment was not refined and the cognition was still shallow, they were determined to persevere. After a long time of experiments, or to detect subtle changes between bottles and dishes, or to analyze and conceal the signs in the data.
The years have passed, and the skills have gradually refined, which has deepened the solution of dibromo-1 and tetrafluorobenzene. From ignorance to clarity, from crude method to exquisite technique. Today, it is used in industry and scientific research, and it is also a brilliant chapter for the chemical scroll. This is the work of the predecessors. Accumulating a few steps to a thousand miles, it has become the history of this thing.
Product Overview
2 - Bromo - 1,4 - Difluorobenzene, also an organic compound. Its color is pure and transparent, and its shape is as clear as a liquid. It has a special smell and can be stored at room temperature and pressure. Its molecular structure is exquisite, and bromine atoms and difluorine atoms are attached to the benzene ring, resulting in its unique chemical properties.
This compound has a wide range of uses in the field of organic synthesis and is often a key raw material for the preparation of fine chemicals. With its active chemistry, it can react with many reagents to derive a variety of organic products. In various fields such as drug research and development, materials science, etc., it has helped to create new drugs, develop new materials, and contribute to scientific progress. It is an indispensable and important substance in organic chemistry research.
Physical & Chemical Properties
2 - Bromo - 1,4 - Difluorobenzene is also an organic compound. Its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, it is mostly liquid, with a specific color and smell. Its boiling point and melting point are fixed, and the boiling point is related to its gasification temperature. The melting point is the boundary between solid state and liquid state.
When it comes to chemistry, bromine and fluorine atoms in this compound give their unique activities. Bromine atoms are active and can participate in many nucleophilic substitution reactions, such as with alkoxides, amines and other reagents, and are prone to substitution products. Fluorine atoms have strong electronegativity, which affects the distribution of molecular electron clouds, and changes the density of benzene ring electron clouds, which in turn affects their reactivity. This compound is widely used in the field of organic synthesis and can be used as an intermediate to form complex organic molecules through a series of reactions. It is also an important substance for chemical research and production.
Technical Specifications & Labeling
There are currently 2 - Bromo - 1,4 - Difluorobenzene, which is related to its technical specifications and identification (product parameters), and should be detailed. Its quality must be pure, and impurities should not exceed the limit of trace amounts. Looking at its color, it should be colorless and clear, without cloudy or heterochromatic defects. Smell it, when there is no peculiar smell. Its boiling point, melting point and other physical constants must meet the established standards. In terms of chemical properties, when encountering conventional reagents, the reaction should be as expected. On the label, the product name, composition, and specification parameters should be clear and correct, so that the viewer can know the details. In this way, it is a qualified product technical specification and identification (product parameters), suitable for all uses.
Preparation Method
To prepare 2 - Bromo - 1,4 - Difluorobenzene, the raw materials and production process, reaction steps and catalytic mechanism are crucial.
First, an appropriate amount of fluorobenzene is taken as the initial raw material, and bromine atoms can be introduced after bromination reaction. In this step, iron powder or iron tribromide is used as the catalyst, and bromine reacts with fluorobenzene at a suitable temperature to undergo electrophilic substitution. Bromine atoms are attached at specific positions in the benzene ring to form a bromofluorobenzene mixture.
Then, selective fluoridation is carried out. Using suitable fluorination reagents, such as anhydrous potassium fluoride, etc., under the action of a phase transfer catalyst, the reaction is heated in a specific organic solvent. Precisely control the reaction conditions so that fluorine atoms replace hydrogen atoms at specific positions in the benzene ring to form the target product 2-Bromo-1,4-Difluorobenzene.
Each step requires strict control of temperature, time and material ratio to improve yield and purity. And post-treatment cannot be ignored. High purity 2-Bromo-1,4-Difluorobenzene can be obtained through extraction, distillation, recrystallization and other steps.
Chemical Reactions & Modifications
Today there is a substance called 2 - Bromo - 1,4 - Difluorobenzene. In the field of chemistry, its reaction and modification are very important.
Looking at the reaction, it can be combined with various reagents, and different products can be produced according to different conditions. Or nucleophilic substitution, or addition reaction, all traces can be followed. Chemists study the mechanism in detail to understand the law of its change.
As for modification, it is the way to increase its utility and change its properties. It can be chemically modified to adjust its activity and stability. Or introduce new groups to change its physicochemical properties to suit different needs.
Chemists, working day and night, hope to deeply understand the secrets of the 2-Bromo-1,4-Difluorobenzene reaction and modification, and contribute to the advancement of science and industry.
Synonyms & Product Names
Today there is a thing called 2 - Bromo - 1,4 - Difluorobenzene. The name of this thing is synonymous, and we should also investigate it. The name of the synonym, so it means the same thing, although the names are different, but the meaning is no different.
In the field of chemical industry, there are many things, which is not uncommon. This 2 - Bromo - 1,4 - Difluorobenzene, either because of its characteristics, production method, or because of its use, has various synonymous names.
Studying its synonymous name is beneficial for academic exchanges and industrial applications. Scholars can use this to understand the different names of this thing, so as not to confuse it; industry players can also communicate accurately and promote the prosperity of the industry. We should carefully examine its synonymous names and trade names to clarify its place in the chemical world and help it be better used in the world.
Safety & Operational Standards
2 - Bromo - 1,4 - Difluorobenzene is an important chemical substance. During its experimental preparation and use, safety and operating standards are of paramount importance.
The first word is safe, this substance has certain chemical activity and potential danger. When storing, be sure to store in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Because it may be irritating and contact with skin and eyes can cause discomfort, it is necessary to wear appropriate protective equipment during operation, such as protective gloves, goggles and lab clothes, to prevent inadvertent contact.
Furthermore, the operating instructions, before the experiment, should be thoroughly familiar with the relevant operating procedures and emergency measures. When taking the substance, use a precise measuring tool, and measure it accurately according to the experimental requirements to avoid waste and excessive use. During the reaction process, strictly control the reaction conditions, such as temperature, pressure and reaction time. When heating, appropriate heating methods should be used to prevent local overheating from causing the reaction to go out of control. If the reaction involves other chemicals, pay attention to their compatibility and add them in the correct order to prevent adverse reactions.
If you accidentally come into contact with the substance, you should immediately rinse the contact area with a large amount of water. If you come into contact with eyes, you need to seek medical attention immediately after rinsing. If a leak occurs, you should quickly evacuate unrelated personnel, turn on ventilation equipment, and collect and clean the leak in an appropriate manner to prevent its spread from causing greater harm.
Only by strictly following safety and operating standards can we ensure the smooth progress of experiments and applications related to 2-Bromo-1, 4-Difluorobenzene, and ensure the safety of personnel and the environment.
Application Area
2 - Bromo - 1,4 - Difluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediary. Through ingenious chemical reactions, it can be combined with many reagents to synthesize specific drugs to cure various diseases.
In the field of materials science, it is also important. After specific treatment methods, it can be integrated into polymer materials, giving it unique properties, such as enhancing the stability and corrosion resistance of materials.
And in the field of electronic chemistry, 2 - Bromo - 1,4 - Difluorobenzene can also show its skills. It is beneficial to the manufacture of electronic components, optimize their electrical performance, and improve the efficiency and reliability of components. From this point of view, this compound has an indispensable position in a variety of application fields, and is actually an important thing in chemical research and industrial production.
Research & Development
Recently, 2 - Bromo - 1,4 - Difluorobenzene has been studied. Its properties are different, and it is often a key agent in various chemical reactions.
At the beginning, to obtain this product, the method is quite difficult, the yield is also low, it takes a long time and costs a lot. However, we continue to study, explore the reaction mechanism in detail, and try various conditions, such as temperature, pressure, and catalyst selection.
After repeated tests, some gains have been made. Finding an efficient method can increase its yield and reduce the time of reaction. And the raw materials used are becoming more common and easy to obtain, and the cost is also reduced.
Looking forward to the future of this product, it will definitely be promising in the fields of medicine and materials. It can be used as the basis for the synthesis of new drugs and can also add luster to new materials. We should continue to study, expand its uses, and promote its wide application to benefit everyone.
Toxicity Research
2 - Bromo - 1,4 - Difluorobenzene, an organic compound. In the matter of toxicity research, we will investigate in detail.
Observe the structure of its molecule, bromine and difluoride atoms are attached to the benzene ring. It may have certain toxicity due to the characteristics of the structure. After various experiments, small animals were used as samples to administer this compound. Observe its physiological changes, see reduced food intake, slow activity, or damage to its nervous system.
And it should not be ignored in the environment. It may be transmitted through water and soil, causing ecological disturbance. Although it is used for industrial use, the risk of toxicity must be prevented. We must study proper methods, control their use, avoid their overflow in the environment, and avoid disasters, so as to ensure the safety of all living beings and the balance of ecology.
Future Prospects
I try to research chemical products. Now look at this product 2 - Bromo - 1,4 - Difluorobenzene, observe its properties, and think about its future development. This product has special qualities and can be used in various fields of chemical industry.
In today's world, science and technology are new, and the chemical industry is following suit. 2 - Bromo - 1,4 - Difluorobenzene may be used to create new materials to meet the needs of equipment and electronics, making it stronger in quality and better in performance. It is the basis for equipment durability and electronic agility.
And the road to medicine, it is also promising. It may open the way for the research of new drugs to treat various diseases and solve the suffering of the world. In the future, we should deeply study its nature and expand its application, so that it can be prosperous in industry and people's livelihood, so as to achieve our expectations for the future and benefit the people.
Where to Buy 2-Bromo-1,4-Difluorobenzene in China?
As a trusted 2-Bromo-1,4-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Bromo-1,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-bromo-1,4-difluorobenzene?
2-% naphthalene-1,4-diethyl ether has many main uses. In the field of organic synthesis, this is an important intermediate. It has a unique structure and can be derived from many organic compounds with special properties and functions through various chemical reactions.
For example, in pharmaceutical chemistry, it is often a key starting material for the synthesis of specific drug molecules. Its structure can impart a specific spatial configuration and chemical activity to drug molecules, which helps to improve the affinity and selectivity of drugs to targets, thereby enhancing drug efficacy and reducing side effects.
In the field of materials science, 2-% naphthalene-1,4-diethyl ether also plays an important role. It can be used to prepare functional materials with special optical and electrical properties. Polymer materials based on it may have good fluorescence properties and can be applied to Light Emitting Diodes, fluorescence sensors and other fields. Due to the conjugated system in the molecular structure, it can effectively absorb and emit light of specific wavelengths, thus exhibiting unique optical phenomena.
Furthermore, in the field of dye chemistry, it also makes a difference. It can be used as an important component in the synthesis of new dyes. With its structural characteristics, it endows dyes with excellent dyeing properties, such as high color fastness and bright color. And its chemical stability allows dyes to maintain good performance under different environmental conditions, meeting the needs of high-quality dyes in textile, printing and dyeing industries. In conclusion, 2-% naphthalene-1,4-diethyl ether, with its unique chemical structure, plays an indispensable role in many fields such as organic synthesis, medicine, materials, and dyes, promoting the development of related industries and technological progress.
What are the physical properties of 2-bromo-1,4-difluorobenzene?
2-% heptyl-1,4-diene benzene, also known as m-divinylbenzene, is an organic compound. Its physical properties are as follows:
In appearance, it is a colorless to light yellow transparent liquid at room temperature and pressure. Under the influence of sunlight or heat, the color will gradually deepen. This form is convenient for processing and transfer in many chemical operations, and the transparency property is conducive to observing its reaction process.
In terms of smell, it has a unique aromatic smell. However, if the concentration of this smell in the air is too high, or it irritates the human respiratory tract, it is necessary to pay attention to ventilation and ventilation when using and storing.
When it comes to the boiling point, it is about 207-208 ° C. A relatively high boiling point means that it is more stable at general ambient temperatures and is not easy to evaporate. In chemical processes such as high-temperature reactions or distillation, it can be separated from other substances according to this boiling point characteristic.
Its melting point is about -66 ° C. A lower melting point indicates that it will not solidify at room temperature and can maintain good fluidity, which is crucial in practical application scenarios such as pipeline transportation.
In terms of density, it is about 0.915-0.925g/cm ³, which is different from the density of water. This density characteristic is of great significance in operations such as liquid-liquid separation. Preliminary separation can be achieved through stratification.
In terms of solubility, it is difficult to dissolve in water, but it can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This characteristic determines its applicability in different reaction systems, and suitable organic solvents can be selected to cooperate with it according to the reaction requirements.
In addition, 2-% heptyl-1,4-diene benzene also has a certain volatility. Although the boiling point is high, some of it will still evaporate into the air in an open system or at a higher temperature. During operation, attention should be paid to and protective measures should be taken to avoid adverse effects on the environment and human body.
What are the synthesis methods of 2-bromo-1,4-difluorobenzene?
The synthesis method of 2-% pente-1,4-diene benzene has been known for a long time, and there are many methods, each of which is ingenious.
First, it can be obtained by the addition reaction of benzene and pentadiene under the action of a suitable catalyst. This reaction requires a catalyst with good activity to promote the smooth progress of the reaction. At the time of the reaction, temperature, pressure and other conditions also need to be precisely controlled to make the reaction efficient and highly selective. If the temperature is too high, it is easy to produce side reactions, resulting in impure products; if the temperature is too low, the reaction rate will be delayed and take a long time.
Second, halogenated benzene and pentadienyl halide are used as raw materials and are achieved by a metal-catalyzed coupling reaction. In this path, the choice of metal catalysts is crucial. Common metal catalysts such as palladium and nickel can effectively catalyze the coupling reaction. At the same time, the ligand in the reaction system also has a great influence on the reaction, and the appropriate ligand can enhance the activity and selectivity of the catalyst, making the reaction more ideal.
Furthermore, the target structure can be gradually constructed from a specific benzene derivative through a multi-step reaction. First, the benzene derivative is functionalized, and a suitable substituent is introduced. After a series of reactions such as elimination and addition, 2-% pente-1,4-diene benzene is finally obtained. Although this method is complicated, it requires relatively mild reaction conditions and can precisely control the product structure.
All these synthesis methods have their own advantages and disadvantages. It is necessary to carefully choose according to the actual situation, such as the availability of raw materials, cost considerations, product purity requirements, etc., in order to efficiently synthesize 2-% pente-1,4-dienobenzene.
What are the precautions for storing and transporting 2-bromo-1,4-difluorobenzene?
For 2-% heptyl-1,4-diene benzene, all things must be paid attention to when it is hidden and transported.
When hiding, place the first importance on it. It should be placed in a cool and dry place, away from direct sunlight, because it is afraid of the invasion of light and heat. If it is exposed by the hot sun, it may cause qualitative change. And when kept away from fire and heat sources, this substance is flammable, and in case of open flame or hot topic, it is dangerous to cause fire. The ventilation of the warehouse must also be good to prevent the accumulation of gas and cause accidents.
It also requires temperature and humidity. The temperature should be controlled within a certain range. If it is too high, it will easily lead to increased volatilization, and if it is too low, it will change the physical properties. The humidity should also not be too high to prevent impurities from being generated by moisture and damaging its purity.
When transporting, the packaging must be solid. Choose the packaging material suitable for this object and seal it tightly to prevent it from leaking. When handling, handle it with care, do not collide, fall, cover its quality or brittle, if it is hit by force and the packaging is damaged, there is a risk of leakage.
Vehicles transported must also comply with the specifications. Equipped with fire extinguishers and emergency materials, so as not to be in danger. When driving, drive slowly to avoid bumps and severe roads, and do not mix with oxidants, acids and other substances, so that it encounters with various substances, or causes severe reactions, endangering safety.
The escort must know the nature of this thing and know the emergency method. Always check the packaging on the way. If there is a leak, take measures quickly to plug the leak, clean the spill, and prevent its spread from causing greater risk. In this way, Tibet and transportation are all careful to ensure 2-% heptyl-1,4-diene benzene safety.
What are the effects of 2-bromo-1,4-difluorobenzene on the environment and human health?
2-% pente-1,4-dienobenzene, its impact on the environment and human health is of great concern. This substance may be stored in the exhaust gas, wastewater generated by specific industrial processes, or in some chemical products.
If it escapes into the atmosphere, it can chemically react with other substances in the air to generate pollutants such as photochemical smog, resulting in a decrease in air quality. In the human respiratory system, it can cause cough, asthma, shortness of breath and other discomfort. Long-term exposure to it may damage lung function and increase the risk of respiratory diseases.
When it enters the water body, it will affect the aquatic ecology. Or cause poisoning of aquatic organisms, interfere with their normal growth and reproduction, and destroy the water ecological balance. If people drink water contaminated by it, harmful substances may accumulate in the body, damage the liver, kidneys and other organs, and endanger their health.
And this substance has a certain volatility. If this pollutant exists in the indoor environment, it will cause the indoor air quality to deteriorate and affect the health of the occupants. Especially people who have been in the environment for a long time, such as factory workers and residents living near the source of pollution, are more likely to be affected by it.
Although this substance is used in specific industrial fields or has its value, proper protective measures and pollution control measures must be taken during production and use to reduce its harm to the environment and human health. At the level of environmental monitoring, it is also necessary to strictly measure its content to ensure environmental quality and personal safety.