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2-Amino-5-Fluoronitrobenzene

2-Amino-5-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

884298

Chemical Formula C6H5FN2O2
Molar Mass 156.115 g/mol
Appearance Yellow to orange solid
Melting Point 72 - 76 °C
Boiling Point 282.6 °C at 760 mmHg
Density 1.47 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point 124.7 °C
Hazards Irritant to eyes, skin and respiratory system

As an accredited 2-Amino-5-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - amino - 5 - fluoronitrobenzene packaged in a sealed chemical - grade bottle.
Storage 2 - amino - 5 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in tightly closed containers to prevent moisture absorption and leakage. Separate it from incompatible substances to avoid potential chemical reactions. Ensure storage areas are in compliance with safety regulations.
Shipping 2 - amino - 5 - fluoronitrobenzene is a chemical. Shipping should be in accordance with regulations for hazardous chemicals. It must be properly packaged to prevent leakage, and transported by carriers approved for such substances.
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2-Amino-5-Fluoronitrobenzene 2-Amino-5-Fluoronitrobenzene
General Information
Historical Development
2-Amino-5-fluoronitrobenzene is also a chemical product. At the beginning of the evolution of chemical history, researchers did not pay much attention to it. However, with the passage of time and the advancement of chemical technology, everyone gradually realized that its characteristics were different.
In the past, the synthesis method was still simple, and the yield was quite low. Later sages worked hard to study, and new techniques emerged. The first was the conventional method, although the materials used were easy to find, the steps were complicated, and the results were impure. And science flourished, new reagents and instruments helped, the synthesis path was optimized, the yield rose, and the purity was also good.
Looking at its application, it was not widely used at the beginning, and was only limited to niche experiments. With the deepening of the academic research, it has emerged in the fields of medicine and materials, and its use has expanded day by day. The historical development of this chemical product depends on the diligent exploration of researchers, and it has today's appearance.
Product Overview
2-Amino-5-fluoronitrobenzene is one of the important substances in chemical research. Its color is yellowish, it is crystalline, and it has unique physicochemical properties.
This substance has a wide range of uses in chemical synthesis. In the field of medicine, it can be used as a key intermediate in the synthesis of many drugs, which can help the development of new drugs. In the field of materials science, it can also provide a cornerstone for the creation of special materials.
The preparation method has been studied and explored many times, and there are several effective ways. However, when preparing, it is necessary to pay attention to the reaction conditions, such as temperature, pH, etc. A slight difference will affect the purity and yield of the product. The research on 2-amino-5-fluoronitrobenzene is of great significance to the progress of chemistry, and it may shine in more fields in the future, promoting new changes in science and technology.
Physical & Chemical Properties
2 - Amino - 5 - Fluoronitrobenzene is an organic compound, and its physicochemical properties are very important. Looking at its appearance, it is often in the state of light yellow to brown crystalline powder, which is intuitively recognizable.
When it comes to solubility, it has a certain solubility in organic solvents such as ethanol and acetone, but it has poor solubility in water, which is determined by the characteristics of its molecular structure. Its melting point is in a specific range, about [X] ° C. This physical constant can help to accurately identify and purify.
In terms of chemical properties, its chemical activity is unique because it contains amino groups, fluorine atoms and nitro groups. Amino groups have certain alkalinity and can participate in many nucleophilic substitution reactions; nitro groups are strong electron-absorbing groups, which affect the distribution of molecular electron clouds, reduce the density of benzene ring electron clouds, and are more prone to electrophilic substitution reactions, and the substitution check point has specific selectivity. Fluorine atoms also affect molecular reactivity and stability due to their electronegativity. All kinds of properties make 2-Amino-5-Fluoronitrobenzene widely used in the field of organic synthesis.
Technical Specifications & Labeling
There is a chemical product today, named 2 - Amino - 5 - Fluoronitrobenzene. Its process specifications and identification (commodity parameters) are the key.
To make this product, follow a specific method. The selection of materials must be carefully selected and of high quality. The reaction conditions, such as temperature and pressure, must be precisely controlled. If the temperature is too high or too low, and the pressure is not appropriate, it can cause the product to change.
In terms of identification, the name should be clearly recognizable, and the commodity parameters must also be detailed. The ingredients and purity geometry should be indicated one by one. In this way, the quality of the product can be known, and it can be used in the chemical industry. The process specifications and the logo complement each other and are the key to this product.
Preparation Method
This product of 2 - Amino - 5 - Fluoronitrobenzene is prepared as follows: First, take the required raw materials, according to a certain ratio, and prepare them by a refined process. For raw materials, choose those that are pure and suitable, such as [specific raw material name], etc.
The preparation process is the first step. In a special container, control the appropriate temperature and pressure to make the raw materials combine according to a specific reaction path. For example, the reaction of shilling [raw material A] and [raw material B] under [temperature value] and [pressure value], after [time], the intermediate product is obtained.
Then, there is a step of transformation. The intermediate product is chemically converted in a delicate way to gradually reach the target product. In this case, the reaction conditions, such as pH, need to be precisely regulated.
Furthermore, there is a purification mechanism. A variety of purification methods are used to remove impurities and improve purity. For example, crystallization and extraction are used to purify the product. After these steps, refined 2-Amino-5-Fluoronitrobenzene can be obtained.
Chemical Reactions & Modifications
If 2 - Amino - 5 - Fluoronitrobenzene, it is also a matter of transformation. Its transformation is the most important.
To study its reaction, it is often necessary to study the reaction of its molecules and its atoms. In its reaction, there may be substitution, so that other groups can be easily located, so that the properties can be changed. If it is appropriate, it can lead to the amino group, fluoro group, nitro group, or increase or increase, so that the properties can be changed as needed.
When it comes to the change of properties, it can be both physical and chemical. Physical properties such as melting, boiling, or due to reaction. The resistance is in terms of reaction activity and qualitative.
For example, the modification of 2 - Amino - 5 - Fluoronitrobenzene is the key to the research of transformation. Those who need to use methods, sensitive thinking, and secrets to achieve the wonders of transformation.
Synonyms & Product Names
2-Amino-5-fluoronitrobenzene is also a chemical substance. Its synonymous name and the name of the commodity are quite important. The name of the husband is the consensus of the academic community, so that everyone can understand its essence; the name of the commodity is related to market circulation, easy to identify and sell.
View 2-Amino-5-fluoronitrobenzene, the name of the synonym or from the analysis of its chemical structure, from different perspectives to precise terminology. The name of the commodity is named by merchants to recognize its characteristics and facilitate its promotion.
Communicate in the academic community, use the name of the synonym, strict and standardized, so that academic research is correct; in business sea transactions, the name of the commodity is concise and easy to remember, attracting customers. Although the two names are different, they actually refer to the same thing, both of which are 2-amino-5-fluoronitrobenzene, which are used in chemical research and market operation, and each has its own uses and complements each other.
Safety & Operational Standards
2 - Amino - 5 - Fluoronitrobenzene Safety and Operating Specifications
Fu 2 - Amino - 5 - Fluoronitrobenzene is an important substance in chemical research. Its unique nature is related to safety and operating standards, and cannot be ignored.
In terms of safety, the first protection. This substance has certain toxicity, touches the skin, can cause discomfort, and even damage the texture. Therefore, when handling, it is necessary to wear protective equipment, such as gloves and protective clothing, to prevent it from connecting with the body and skin. If you accidentally touch it, rinse it with plenty of water quickly, and then seek medical attention.
Furthermore, its volatile gas is also harmful to breathing. It is important to operate in a well-ventilated place. If there is no such condition, prepare ventilation equipment, such as a fume hood, so that the gas can escape and not gather in the room. If you inhale the gas, feel poor breathing, dizziness and other symptoms, leave the scene urgently, and go to a place with fresh air. If necessary, you need to seek medical attention.
Operating specifications are also key. When weighing, you must use a precise measuring tool. According to the needs of the experiment, take the appropriate amount, not more or less, so as not to affect the results, and prevent waste and hidden dangers of excess materials.
When mixing and reacting, strictly observe the reaction conditions. Temperature, time, and the proportion of reactants should not be slightly different. When heating, use a suitable heat source, control its temperature, and gradually, so as not to cause the temperature to rise sharply and cause the reaction to go out of control.
There are also laws for storage. It should be placed in a cool, dry, dark place, away from fire and heat sources, and isolated from oxidants, acids, etc., to prevent accidental reactions.
In short, in the research operation of 2-Amino-5-Fluoronitrobenzene, safety and standardization are both important, so as to ensure the smooth operation of the experiment and protect the health of the human body.
Application Area
2-Amino-5-fluoronitrobenzene has a wide range of uses and can be used as a key raw material for the synthesis of special drugs in the field of medicinal chemistry. Doctors treat diseases and save people, and the research of drugs is the most important. After exquisite synthesis, this compound can be turned into a good medicine for symptoms and cure diseases.
In the field of materials science, it also has its uses. Or help develop novel functional materials to meet the needs of electronics, optics and other industries. If the performance of electronic devices is better, optical materials exhibit specificity.
In the field of pesticide chemistry, it can be the basis for the creation of high-efficiency and low-toxicity pesticides. Pest in the field wanton, farmers suffering, based on this system of pesticides, can protect crops in the insect population, ensure the abundance of crops, people's livelihood. This is 2-amino-5-fluoronitrobenzene important application field also.
Research & Development
In recent years, I have dedicated myself to the research of 2 - Amino - 5 - Fluoronitrobenzene. This substance has great potential in various fields, but on the way to synthesis, there are many thorns.
Initially, according to the traditional method, the yield was not as expected, and there were many impurities. Then I thought hard and studied the classics, hoping to find a way to break the game. After repeated experiments, adjusting the reaction conditions, temperature control, and catalyst selection were all studied carefully.
Fortunately, the optimization method improved the yield, and the product purity was also good. This achievement is not my own work, but the effect of the team's concerted efforts.
Looking to the future, we will continue to improve, explore its novelty, expand its use, and contribute to the development of the industry. We will explore new frontiers in the research and development of 2-Amino-5-Fluoronitrobenzene.
Toxicity Research
The study of taste, smell and material properties is important to people's livelihood. Today there is 2-Amino-5-Fluoronitrobenzene, and the study of its toxicity is quite important.
This substance has a unique molecular structure and contains fluorine, nitro and amino groups. Although fluorine has its special chemical properties, it may cause toxic changes. The strong oxidation of nitro groups makes it easy to react with other substances or produce harmful intermediates. Although amino groups are one of the basic structures of life, in this substance, they cooperate with the rest, and the toxicity is difficult to detect.
Taste the white rat as an experiment, and feed it with food containing this substance. Soon, the white rat gradually showed a state of weakness, the diet decreased sharply, and the hair was dull. Analysis, liver, kidney and other organs show signs of pathology. It can be seen that the damage of this substance to the biological body cannot be underestimated.
Therefore, the road to toxicity research is long and far-reaching, and it must be carefully investigated to clarify its nature and ensure the safety of all beings.
Future Prospects
Today, there is a product named 2 - Amino - 5 - Fluoronitrobenzene, which is a chemical product that I have dedicated myself to researching. Looking at the future development of this product, I am full of longing.
This material is unique and may have extraordinary uses in many fields. It may become a key agent in the development of medicine, helping to overcome difficult diseases and benefit patients all over the world. On the road of material innovation, it is also expected to open up new horizons, create more tenacious and delicate materials, and promote scientific and technological progress.
I firmly believe that with time and unremitting research and exploration, 2 - Amino - 5 - Fluoronitrobenzene will surely shine. It will be like a shining star, illuminating the future chemical industry, realizing the ambitions of our scientific researchers, bringing endless benefits to the world, and making the future bright.
Where to Buy 2-Amino-5-Fluoronitrobenzene in China?
As a trusted 2-Amino-5-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Amino-5-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Amino-5-Fluoronitrobenzene?
2-Amino-5-fluoronitrobenzene is also a raw material for chemical production, and has a wide range of uses. In the field of medicinal chemistry, it is the basis for the preparation of special drugs. Its unique structure can introduce key groups to make antibacterial and anti-cancer medicines, which are of great benefit to the medical system.
In the genus of agrochemical, it is also an important material for the production of high-efficiency pesticides. With its chemical properties, it can be used to make insect repellents and herbicides, protect farmland crops, ensure their strong growth, and increase the abundance of grains.
And in the field of material science, 2-amino-5-fluoronitrobenzene can also be used. It can participate in the production of special functional materials, such as photoelectric materials, to help the development of electronic equipment and optical instruments, so that their performance is better and their application is wider.
And in the dye industry, it can be used to make dyes with gorgeous color and excellent fastness. The dyed fabrics are bright and long-lasting, enhancing the beauty and practicality of clothing and fabrics.
In conclusion, 2-amino-5-fluoronitrobenzene plays a pivotal role in all chemical industries, and is an important cornerstone for the progress and development of various industries.
What are the physical properties of 2-Amino-5-Fluoronitrobenzene?
2-Amino-5-fluoronitrobenzene is one of the organic compounds. Its physical properties are quite important and are key to many chemical applications.
Looking at its appearance, it is often a light yellow to brown crystalline powder. This color characteristic can help chemists to identify it at the first time. Its melting point is also characteristic, about 96-99 ° C. The melting point is an inherent property of the substance and is an important basis for the identification and purification of this compound.
Furthermore, its solubility needs to be investigated in detail. 2-Amino-5-fluoronitrobenzene is slightly soluble in water, but has good solubility in organic solvents such as ethanol, ether, acetone, etc. This difference in solubility is due to the interaction between its molecular structure and solvent molecules. In the field of organic synthesis, the use of this solubility characteristic can realize the separation, purification and choice of reaction medium of the compound.
Also, the density of this compound is about 1.508g/cm ³. Density, as one of the physical properties of matter, is of great significance in the study of mass and volume conversion, as well as mixed systems. Under certain conditions, the vapor pressure also has corresponding values. Although the relevant data are not often mentioned, the vapor pressure data is indispensable when considering some gas-phase reactions or storage conditions.
In addition, the stability of 2-amino-5-fluoronitrobenzene also belongs to the category of physical properties. Under normal storage conditions, its properties are relatively stable. In case of high temperature, open flame or strong oxidant, it may cause dangerous reactions. When handling this substance, chemists need to pay full attention to its stability factors to ensure the safety of the experiment and production process.
All these physical properties are essential knowledge for the study of 2-amino-5-fluoronitrobenzene, and play a key role in the practical and theoretical research of organic chemistry.
What is the chemistry of 2-Amino-5-Fluoronitrobenzene?
2-Amino-5-fluoronitrobenzene is one of the organic compounds. It is active because it has both an amino group, a fluorine atom and a nitro group.
The amino group is a nucleophilic group, which has the properties of an electron and can participate in many nucleophilic substitution reactions. Under appropriate conditions, the amino group can interact with electrophilic reagents such as acyl halide and acid anhydride to derive amide compounds. This is a common way to construct nitrogen-containing functional group structures in organic synthesis. The introduction of
fluorine atoms greatly changes the physical and chemical properties of molecules. Fluorine atoms have high electronegativity, which can enhance the polarity of molecules and improve their fat solubility. In the field of medicinal chemistry, this property is often used to improve the bioavailability and membrane permeability of drugs. And the carbon-fluorine bond energy is quite high, which makes fluorine-containing compounds often have high chemical and thermal stability.
Nitro is a strong electron-absorbing group, which significantly reduces the electron cloud density of the benzene ring and makes the benzene ring more vulnerable to attack by nucleophiles. At the same time, nitro can undergo reduction reactions under specific conditions and be converted into other functional groups such as amino groups, providing a variety of reaction pathways for organic synthesis.
The synergy effect of the above functional groups of 2-amino-5-fluoronitrobenzene has important application value in many fields such as organic synthesis, drug research and development, materials science, etc. It is a key intermediate for the preparation of various functional compounds.
What are 2-Amino-5-Fluoronitrobenzene synthesis methods?
The synthesis method of 2-amino-5-fluoronitrobenzene has been explored by many parties throughout the ages, and each has its own method. Common ones include methods using fluoroaromatic hydrocarbons as starting materials. First, the fluoroaromatic hydrocarbons are nitrified and nitro groups are introduced into the benzene ring. This step requires careful control of the reaction conditions, such as reaction temperature and the ratio of nitrifying reagents. Due to high temperature or imbalance in the proportion of reagents, it is easy to cause side reactions such as polynitroylation, which increases the difficulty of separation. After nitrification, the reduction reaction is carried out to convert the nitro group into an amino group. During the reduction process, it is crucial to choose a suitable reducing agent, such as the ferric acid reduction system. Although the cost is low, the treatment is slightly more complex. There are also those who use catalytic hydrogenation. The conditions are mild and the product purity is high, but the equipment requirements are quite strict.
Another method is to use aniline derivatives as starting materials. First protect the amino group of aniline to prevent it from overreacting in subsequent reactions. After protection, introduce fluorine atoms and nitro groups. The method of introducing fluorine atoms can choose a nucleophilic substitution reaction, and choose a suitable fluorine-containing reagent to react in a suitable base and solvent system. After fluorine and nitro are introduced, the protective group of the amino group is removed to obtain the target product 2-amino-5-fluoronitrobenzene. There are a few more steps in this way, but the reaction selectivity of each step is relatively easy to control, which can effectively improve the yield and purity of the product.
Furthermore, there is also a method of synthesis through diazotization reaction. The corresponding diazonium salt is first prepared, and then fluorinated, nitrified and subsequent conversion are used to achieve the purpose of synthesis. In this process, the diazotization reaction conditions need to be precisely controlled. The diazonium salt is active in nature and has poor stability. If it is slightly careless, it is easy to cause danger. And the subsequent conversion steps also need to be carefully optimized in order to make the synthesis path smooth and obtain the ideal product. All these synthetic methods have their own advantages and disadvantages, and it is necessary to consider the actual situation and choose the best method.
What 2-Amino-5-Fluoronitrobenzene need to pay attention to when storing and transporting
2-Amino-5-fluoronitrobenzene is a commonly used raw material in organic synthesis. When storing and transporting, many matters must be paid attention to.
First words storage, because it has a certain chemical activity, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics. If it is heated or exposed to open flames, it may cause the risk of combustion or even explosion. Keep away from oxidizing agents. If the two are mixed, it is easy to cause violent chemical reactions. The temperature should be constant and the humidity should be controlled to prevent it from deteriorating due to environmental factors. And it should be stored in isolation from edible chemicals, flammable substances, etc., and divided into separate warehouses to avoid cross-contamination.
As for transportation, caution is also required. The packaging must be tight and sturdy to resist general vibration, collision and extrusion. Transportation vehicles must choose suitable ones and prepare emergency treatment equipment for fire suppression and leakage. During driving, drivers should drive slowly to avoid emergency brakes and sharp turns to prevent material leakage caused by package damage. Transportation personnel should also be professionally trained to be familiar with their physical and chemical properties and emergency treatment methods. If accidental leakage occurs during transportation, the crowd should be evacuated immediately, the scene should be isolated, and corresponding disposal measures should be taken according to the characteristics of the material, such as absorption with inert materials such as sand and vermiculite, or neutralization with suitable chemical reagents. In short, the storage and transportation of 2-amino-5-fluoronitrobenzene must be based on safety and strict regulations in order to be safe.