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2-Amino-5-Bromo Trifluoromethoxy Benzene

2-Amino-5-Bromo Trifluoromethoxy Benzene

Hongda Chemical

Specifications

HS Code

859859

Chemical Formula C7H5BrF3NO
Molecular Weight 260.02
Appearance Solid (Typical)
Color White to Off-White
Boiling Point N/A (decomposes before boiling)
Melting Point 46 - 48 °C
Density N/A
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point N/A
Purity Typically high - 97%+ (depending on source)

As an accredited 2-Amino-5-Bromo Trifluoromethoxy Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2 - amino - 5 - bromo Trifluoromethoxy Benzene in sealed, chemical - resistant container.
Storage Store 2 - amino - 5 - bromo Trifluoromethoxy Benzene in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. It should be stored in a tightly - sealed container to prevent moisture absorption and evaporation. Label the storage container clearly to avoid confusion. This helps maintain its chemical integrity and ensure safety.
Shipping 2 - amino - 5 - bromo Trifluoromethoxy Benzene is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to strict chemical transport regulations. Shipment is via carriers experienced in handling hazardous chemicals to ensure safe and compliant delivery.
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2-Amino-5-Bromo Trifluoromethoxy Benzene 2-Amino-5-Bromo Trifluoromethoxy Benzene
General Information
Historical Development
In the past, the field of chemistry was not as prosperous as it is today, and the research of matter has not been refined. However, those with lofty ideals will make unremitting efforts to explore the unknown secrets.
2 - Amino - 5 - Bromo Trifluoromethoxy Benzene The origin of this compound is also gradually observed by researchers in the exploration of various reactions. At that time, the experimental method was still simple, and the equipment was not refined, but everyone tried it again and again with perseverance.
After years have passed, the art of chemistry has advanced day by day. The method of analysis is more refined, and the skill of synthesis is more and more ingenious. The cognition of 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene is self-ignorant and gradually clear. From the beginning, we can learn about its structure and characteristics in detail, and the hardships in between are beyond words.
Today, this compound is used in the fields of medicine and materials. The road of exploration in the past has laid the foundation for today's widespread use, and its historical evolution has also witnessed the vigorous development of chemistry.
Product Overview
Today there is a thing called 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene. This substance is also, what is the shape? What is the sex like? Let me tell you.
Looking at its appearance, it is white to light yellow powder or crystalline, and when viewed under light, it has a shining brilliance. As for its properties, it is quite unique. Its melting point is moderate, its stability is good, and it is not easy to change under normal circumstances.
This substance is widely used in the field of chemistry. It can be used as a raw material for the synthesis of many fine chemicals and help the great cause of organic synthesis. The amino, bromine and trifluoromethoxy groups contained in it each have their own functions and cooperate with each other. In chemical reactions, they can cause various changes and create various novel and useful products. Although it is a small matter, it is indispensable for the development of chemical industry.
Physical & Chemical Properties
2-Amino-5-bromotrifluoromethoxylbenzene has specific physical and chemical properties. Its color or pure state, solid at room temperature, dense texture. Melting point, about a specific value, this is the key temperature of the substance from solid to liquid, reflecting the stability of its lattice structure.
Regarding chemical properties, its amino group is nucleophilic and can be used as a nucleophilic reagent in many reactions, interacting with electrophilic reagents to cause substitution reactions. Bromine atoms are active and can be converted into functional groups through specific chemical reactions. The existence of trifluoromethoxy groups endows this compound with unique electronic and spatial effects, which affect its reactivity and selectivity. Due to its fluorine-containing atoms, it has strong electronegativity, which changes the polarity of molecules, thereby affecting their solubility and stability. These physicochemical properties have important application value in organic synthesis, drug development and other fields.
Technical Specifications & Labeling
Today there is a product called 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene. In the preparation process, strict regulations should be followed. The selection of raw materials needs to be carefully selected, and impurities should not enter, so as to ensure the purity of the product. When reacting, various parameters such as temperature and pressure must be precisely controlled. If the temperature is too high, the product may decompose; if it is too low, the reaction will be slow. The same is true for pressure, and if it is not appropriate, it will affect the reaction process.
The method of testing is related to quality. Use professional instruments to measure its purity and structure. If the purity is not up to, it cannot enter the market. If the structure does not match, it is not a qualified product. In this way, by strictly adhering to technical specifications and identification (product parameters), we can obtain high-quality products, establish a firm foothold in the industry, and benefit various applications.
Preparation Method
The preparation method of 2-amino-5-bromotrifluoromethoxylbenzene is related to the raw material and production process, reaction steps and catalytic mechanism.
To prepare this product, first take an appropriate amount of specific halogenated benzene as the starting material. This halogenated benzene needs to contain suitable substituents to facilitate subsequent reactions. Place it in a reactor and add an appropriate amount of alkali. The function of the base is to adjust the pH of the reaction environment and promote the reaction. Then add a specific amination reagent. This reagent can introduce amino groups, which is one of the keys to generating the target product. Under a certain temperature and pressure, stir the reaction. Temperature control is very important. If the temperature is too high, side reactions will increase; if it is too low, the reaction rate will be slow. The reaction steps of
are rigorous and orderly. First, the halogenated benzene interacts with the base to form an active intermediate, and then the amination reagent reacts with it quickly to form an intermediate containing amino groups. At this time, the reaction time needs to be carefully regulated to ensure that the reaction is sufficient. In terms of the catalytic mechanism of
, a specific metal catalyst is selected, which can effectively reduce the activation energy of the reaction and accelerate the reaction process. The catalyst and the reactants form a specific complex, changing the reaction route and improving the selectivity of the reaction.
After the above steps, a relatively pure 2-amino-5-bromotrifluoromethoxybenzene can be obtained. This preparation method pays attention to the precise control of each link to achieve the purpose of efficient production.
Chemical Reactions & Modifications
There is now a chemical substance, named 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene. In the reaction and modification of chemistry, it is the gist of research.
Looking at this substance, its structure is exquisite and the atomic arrangement is orderly. To understand its chemical reaction, it is necessary to study the influence of various conditions. If the temperature rises, the molecular activity will increase greatly, the reaction rate may change abruptly, and if it is too high, it may cause a cluster of side reactions. The pH adjustment is also related to the direction of the reaction. In the acidic environment, some groups may be active, promoting the reaction; in the alkaline domain, it may lead to other changes.
When it comes to modification, it aims to give it new energy. It can be replaced with specific atoms or groups by means of substitution to change its physical and chemical properties. Or make its solubility change, or increase its stability, so that it is suitable for more scenarios, adding to the innovation and development of chemistry, and playing a big role in various fields.
Synonyms & Product Names
2-Amino-5-bromotrifluoromethoxybenzene, this substance is quite important in our chemical research. Its synonyms and trade names are like stars, each with its own use. In ancient books, although there is no exact name, the principles of chemistry are the same in ancient and modern times.
Now look at this 2-amino-5-bromotrifluoromethoxybenzene, its synonyms are different, either due to different production methods or due to special characteristics. Its trade name is ordered by the merchant for the convenience of distinction and promotion, according to its characteristics. The synonyms and trade names of this substance both carry the road of chemical research, or are the crystallization of the wisdom of predecessors, or the cornerstone of future exploration. We chemical students should study its name in detail to clarify its nature, explore its rationale, and move forward steadily on the road of chemistry, so as to reveal the mysteries of matter and contribute to the development of chemistry in future generations.
Safety & Operational Standards
2-Amino-5-bromotrifluoromethoxybenzene is an important chemical substance. Safety and handling practices are of paramount importance during research and application.
For storage, keep in a cool, dry and well-ventilated place. Avoid open flames, hot topics, and keep away from sources of ignition to prevent accidents. Due to its chemical properties, in case of heat or open flames, there is a risk of violent reactions, fire or explosion.
When operating, appropriate protective equipment must be worn. Wear protective gloves to protect your hands from direct contact with substances; wear protective glasses to prevent splashing into your eyes and damage your eyesight. Wear protective clothing to protect the whole body from chemical substances eroding your skin.
In the experimental or production site, ventilation equipment must be complete. The volatile gas of this substance may be toxic, and good ventilation can disperse it in time to keep the air fresh and protect the health of personnel. During the operation, the action should be steady and careful, and the substance should not be spilled. If there is a spill, it should be dealt with quickly according to specific procedures. Cut off the fire source first to avoid ignition and explosion. Then use appropriate materials to absorb and clean up, properly dispose of the waste, and do not discard it at will to prevent pollution to the environment.
When using this substance, it is necessary to know its chemical properties and reaction mechanism in detail. Follow the established experimental steps and operating procedures and do not change them without authorization. Every step of operation is related to safety and experimental results. After operation, carefully clean the equipment and site to remove residual substances.
In this way, strictly abide by safety and operating standards, so as to ensure the safety of personnel, protect the environment and promote the smooth progress of scientific research and production in the research and application of 2-amino-5-bromotrifluoromethoxybenzene.
Application Area
2-Amino-5-bromotrifluoromethoxylbenzene is useful in various fields. In the field of medicine, it is the key raw material for the synthesis of specific drugs, which can help physicians make good medicines for treating difficult diseases and treating diseases and diseases for all living beings. In the field of material science, it can be cleverly combined to generate novel materials with specific properties, which are either very tough or well insulated, and have a wide range of uses. In agriculture, it can be used as the basis for the development of high-efficiency and low-toxicity pesticides, protecting crops from insect infestation, and protecting the grain. It has a wide range of uses, like stars shining brightly, and shines uniquely in various application fields. It is a rare and important chemical substance that contributes extraordinary power to promoting the progress of many industries.
Research & Development
There is now a thing named 2-amino-5-bromotrifluoromethoxylbenzene, and I have devoted myself to studying it.
At the beginning, I explored its molecular structure, explained the order of atomic connections, and knew its spatial state. Also observe its physical properties, observe its color state, measure its degree of melting and solubility.
Then, study its chemical properties. Explore its reaction with various reagents, observe its bond formation and bond breaking changes, and investigate its reaction mechanism. After repeated attempts, observe its reaction differences under different conditions.
What we have obtained now, its properties and reactions are clearly understood. However, if you want to use it in practice, you still need to study it in depth. Looking forward to expanding its application in the future, making achievements in medicine, materials and other fields, promoting the transformation of its results, and seeking well-being for everyone, this is my ambition, and the driving force for unremitting research.
Toxicity Research
Wenfu 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene, for our chemical researchers, its toxicity study is crucial.
Looking at the current research, we must first examine the molecular structure. This compound has a unique structure, and the position of bromine and trifluoromethoxy may affect its toxicology. According to past experience, compounds containing halogen atoms often have different toxicity.
Reviewing its mechanism of action may disturb the cellular metabolic pathway. Or cause errors in intracellular signaling, or damage the integrity of cell membranes. All of this requires fine experiments to prove our speculation.
Furthermore, the choice of experimental animals is also critical. Mice and rats were selected to observe their reactions after oral, percutaneous or inhalation. Observe the changes in behavior and physiological indicators, and analyze the characterization of toxicity in detail.
The road to toxicity research is long, and we need to adhere to a rigorous attitude and investigate it carefully. To clarify the toxic nature of 2-Amino-5-Bromo Trifluoromethoxy Benzene, lay a solid foundation for its application and protection.
Future Prospects
Wuguanfu 2 - Amino - 5 - Bromo Trifluoromethoxy Benzene This product is unique and has extraordinary potential. We can have high hopes for its future development. Although the current knowledge is limited, it will surely shine in time.
Today's technology is new and research is advanced. This compound may emerge in the field of medicine, providing new paths for the treatment of various diseases. Or in materials science, it has become the key to creating novel materials, helping to change many industries.
Our scientific researchers should study diligently and deeply explore its characteristics and uses. We hope to make unremitting efforts to uncover its mysterious veil, so that it can be fully realized in the future, contribute to human well-being, and achieve a brilliant career, living up to the prospect of the future.
Where to Buy 2-Amino-5-Bromo Trifluoromethoxy Benzene in China?
As a trusted 2-Amino-5-Bromo Trifluoromethoxy Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Amino-5-Bromo Trifluoromethoxy Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Amino-5-Bromo Trifluoromethoxy Benzene?
2-Amino-5-bromotrifluoromethoxybenzene is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
It plays a pivotal role in medicinal chemistry. Using this as a starting material, through a series of delicate chemical reactions, it can construct many biologically active molecular structures, paving the way for the development of new drugs. For example, it can be linked to other compounds containing active groups through specific reactions to create drug molecules with affinity and inhibitory activity to specific disease targets, assisting the development of anti-disease drugs.
In the field of materials science, it also shows unique uses. With its special chemical structure, it can participate in the preparation of functional materials with specific properties. For example, in the preparation of optoelectronic materials, it can be introduced as a structural unit, endowing the material with unique electron transport and optical properties, and contributing to the development of new optoelectronic materials.
In addition, in the field of pesticide chemistry, 2-amino-5-bromotrifluoromethoxylbenzene can also play a role. After reasonable chemical modification and transformation, pesticide ingredients with efficient pest control effects can be prepared, providing an effective means for agricultural pest control. In short, due to its structural characteristics, it is an important basic substance in organic synthesis in many fields, promoting research and development in various fields.
What are the synthesis methods of 2-Amino-5-Bromo Trifluoromethoxy Benzene
The synthesis method of 2-amino-5-bromotrifluoromethoxylbenzene is quite complicated and diverse. Common ones can be obtained from the starting material through multiple steps.
First, start with a benzene ring compound containing a specific substituent. Before the appropriate conditions, the benzene ring is brominated. This bromination process requires careful selection of brominating reagents, such as bromine, N-bromosuccinimide (NBS), etc. If bromine is used, it is often necessary to use a suitable catalyst, such as iron powder or iron tribromide, to precisely replace the bromine atom in a specific position of the benzene ring to achieve the target bromine substitution product.
Next, the trifluoromethoxy group is introduced. This step can be achieved by nucleophilic substitution reaction. Select a suitable trifluoromethoxylation reagent, such as potassium trifluoromethoxy, etc., and react under a specific solvent system and temperature conditions. The solvent may be a polar aprotic solvent, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc., in order to create an environment conducive to the reaction, so that the trifluoromethoxy group can be successfully integrated into the benzene ring.
In addition, the introduction of amino groups is also the key. Or by the method of nitro reduction. First nitrate the benzene ring and introduce nitro groups. Mixed acid (a mixture of nitric acid and sulfuric acid) is commonly used in nitrification reactions. According to the characteristics of the reaction substrate, the ratio of mixed acid and the reaction temperature are precisely adjusted to introduce nitro groups into the appropriate position. Then, the resulting nitro compound is reduced with a suitable reducing agent, such as hydrogen-palladium-carbon catalytic reduction system, or iron powder-hydrochloric acid system, etc., to obtain an amino group, and finally 2-amino-5-bromotrifluoromethoxylbenzene.
Or there may be other synthesis paths, but the reaction route needs to be carefully designed according to the availability of raw materials, the ease of control of reaction conditions, and the cost. Efficient synthesis of this compound can be achieved.
What are the physical properties of 2-Amino-5-Bromo Trifluoromethoxy Benzene?
2-Amino-5-bromotrifluoromethoxy benzene, this physical property belongs to the category of organic compounds. Looking at its chemical structure, bromine atoms, trifluoromethoxy groups and amino groups live in specific positions and interact, resulting in unique physical properties.
First of all, under normal temperature and pressure, it often takes the shape of white to pale yellow crystalline powder, with fine texture. This color state is derived from the distribution of electron clouds and energy level transitions within the molecule. Light interacts with it, and light of a specific frequency is absorbed or reflected, resulting in this color.
As for the melting point, it has been experimentally measured to be about [X] ° C. The value of the melting point is closely related to the intermolecular forces. There are van der Waals forces, hydrogen bonds and other forces between molecules. In this compound, the amino group can participate in the formation of hydrogen bonds, which enhances the intermolecular forces, and requires a higher temperature to overcome them, thus presenting a specific melting point.
In terms of solubility, it shows good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide. Due to the principle of "similar miscibility", the intermolecular forces between the organic solvent molecules and the compound are suitable and can be interspersed and mixed with each other. In water, the solubility is poor. Because water is a strong polar solvent, it has a large polar difference and weak interaction with the compound molecules.
Volatility is relatively low. The molecular mass is large and the intermolecular force is strong. It requires high energy for the molecule to escape from the liquid phase and enter the gas phase. Therefore, the volatility is not high, and it exists more stably in the solid or liquid state at room temperature.
The density is about [X] g/cm ³, which depends on the molecular mass and the way of molecular accumulation. The molecular mass is determined. When the molecular mass is determined, in the solid or liquid state, the degree of molecular accumulation determines the density.
The physical properties of 2-amino-5-bromotrifluoromethoxylbenzene are determined by their unique chemical structure. They have specific applications and significance in the fields of organic synthesis, drug development, etc. Due to these properties.
What is the market price of 2-Amino-5-Bromo Trifluoromethoxy Benzene?
I don't have the exact market price of 2-amino-5-bromotrifluoromethoxylbenzene. However, if you want to check its price, you can explore it from several ends.
First, the trading platform for chemical raw materials is an important place. In today's world, many chemical products are sold on online platforms, and such platforms gather suppliers, and the prices are also listed. You can go to the well-known domestic chemical trading network, such as Mobell, to search for this product in detail with keywords, or you can get quotations from different manufacturers, and you can also observe the ups and downs of its price and the price differences under different batches.
Second, communicate directly with suppliers. In the chemical industry, manufacturers and distributors have first-hand price information. You can use industry exhibitions and B2B platforms to find suppliers of this product, and inquire by email, phone, etc. When inquiring, it is advisable to specify the required quantity, purity requirements, delivery place, etc., because all factors can change the price.
Furthermore, industry information and reports are also valuable sources. Professional media and consulting organizations in the chemical industry often publish industry reports, which may involve the price trend of specific products, market supply and demand analysis. Such as ICIS, ICIS and other institutions, their reports are based on extensive market surveys and data collection, which can help us know the macro trend and future trend of this product price.
In addition, market supply and demand, raw material costs, policies and regulations, and international situations can all influence the price of 2-amino-5-bromotrifluoromethoxybenzene. If the market demand for this product is strong, and the supply is tight, the price may rise; the price of raw materials fluctuates, which will also cause changes in production costs, which will affect the selling price. Changes in policies and regulations on environmental protection and production qualifications can also indirectly affect the price. If the international situation is turbulent, trade policies, exchange rate fluctuations, etc., may cause changes in the price of this product. Therefore, when looking at its market price, we should comprehensively consider all factors.
What are the precautions for storing and transporting 2-Amino-5-Bromo Trifluoromethoxy Benzene?
2-Amino-5-bromotrifluoromethoxylbenzene is an organic compound. When storing and transporting, there are many key things to pay attention to.
One is related to storage. This compound should be stored in a cool, dry and well-ventilated place. Because it is sensitive to heat, high temperature can easily cause it to deteriorate or cause chemical reactions, so it should be kept away from heat sources and open flames. At the same time, air and moisture may also affect it, and it needs to be sealed to prevent contact with oxygen, moisture and other substances in the air. For example, it can be placed in a sealed glass or plastic bottle, tightly sealed to avoid external factors. In addition, it should be stored separately from oxidizing agents, acids, alkalis and other chemicals to prevent uncontrollable chemical reactions and endanger safety.
Second, for transportation. The transportation process must ensure that the packaging is complete and well sealed to prevent leakage. Because of its certain toxicity and irritation, once leaked, it will not only cause pollution to the environment, but also may endanger the health of transporters. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment. If leakage unfortunately occurs, it can be properly handled in time. When transporting, follow relevant transportation regulations and standards, choose appropriate transportation methods and routes, avoid densely populated areas and environmentally sensitive areas, and minimize latent risks. In conclusion, whether it is storage or transportation of 2-amino-5-bromotrifluoromethoxylbenzene, it must be treated strictly to ensure the safety of personnel and the environment.