2-Amino-4-Fluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code	970470
Chemical Formula	C7H8FNO
Molar Mass	141.143 g/mol
Appearance	Solid (likely, based on similar compounds)
Solubility In Water	Low (due to non - polar benzene ring and relatively small polar groups)
Solubility In Organic Solvents	Good in common organic solvents like ethanol, dichloromethane
Odor	Amines often have a pungent odor, this may have a characteristic amine - like smell

As an accredited 2-Amino-4-Fluoro-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - amino - 4 - fluoro - 1 - methoxybenzene packaged in a sealed plastic bottle.
Storage	Store 2 - amino - 4 - fluoro - 1 - methoxybenzene in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and evaporation. It should be separated from incompatible substances to avoid potential reactions. Label the storage container clearly for easy identification.
Shipping	2 - amino - 4 - fluoro - 1 - methoxybenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and exposure during transit.

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General Information

Historical Development

2 - Amino - 4 - Fluoro - 1 - Methoxybenzene is also a chemical substance. Looking back at its historical development, chemists in the past were diligent in the field of organic synthesis, hoping to expand new ways. At that time, organic chemistry was first emerging, and everyone explored the properties and synthesis paths of various compounds.
Among many attempts, some wise people paid attention to the structure of benzene series containing fluoride, amino group and methoxy group, thinking about its unique properties or possible uses. After years of unremitting experiments, the method of synthesizing this compound has been gradually clarified from the selection of raw materials, the consideration of reaction conditions, and even the improvement of technology. From the initial crude method to the later precise and controlled process, 2-Amino-4-Fluoro-1-Methoxybenzene is a laboratory product that can be prepared on an industrial scale, providing a powerful tool for chemical research and industrial applications.

Product Overview

2-Amino-4-fluoro-1-methoxybenzene is an important product of chemistry. This substance has a unique structure, with amino groups, fluorine atoms and methoxy groups in their respective positions, affecting each other, resulting in unique properties.
Looking at its chemical properties, the amino group is basic and can participate in many nucleophilic reactions; fluorine atoms have strong electronegativity, which can affect the electron cloud distribution of molecules and change the reaction activity; methoxy groups can produce electronic effects on the benzene ring, which affects the overall reaction performance.
In the process of synthesis, fine planning steps are required. Select suitable starting materials and control precise reaction conditions, such as temperature and catalyst selection, to obtain this product. This product has potential applications in the fields of medicine, materials, etc., or is a key intermediate for the creation of new drugs, or plays a unique role in the research and development of new materials.

Physical & Chemical Properties

2-Amino-4-fluoro-1-methoxybenzene, its physicochemical properties are related to research and are of great importance. This substance is light yellow in color and like a crystalline powder, and its properties are still stable at room temperature. Its melting point is quite clear, about a certain degree, which can be a sign of identification.
When it comes to solubility, it dissolves easily in organic solvents such as ethanol and ether. This property is very beneficial for extraction and separation. And it has a certain volatility, in a specific environment, and in the air.
Its chemical activity cannot be ignored. The position of amino group, fluoro group and methoxy group makes it possible to combine with a variety of reagents to form various new substances. It is widely used in the field of organic synthesis. The study of the rationality of this substance can provide a solid foundation for the progress of related industries.

Technical Specifications & Labeling

Today, there is 2-amino-4-fluoro-1-methoxybenzene, which is quite important in the field of chemical industry. Its process specifications and identification (product parameters) are related to the quality and application effectiveness.
For process specifications, the selection of raw materials must be pure and positive, and the ratio must be accurate. The temperature, pressure and time of the reaction must be strictly controlled. If in a reactor, the temperature should be measured with an accurate instrument, and the fluctuation should not exceed a few degrees; the pressure should be constant, according to the preset value, there should be no chaos in the millimeter. The duration should also be according to the established procedure, and it should not be over or under. In terms of
identification (product parameters), the purity should reach a very high standard, and the impurity content should be minimal. Appearance should have a specific color and state, pure color and uniform shape. The number of physical and chemical properties, such as melting point, boiling point, solubility, etc., are all fixed. Only by using this standard can we prove that its quality is high and suitable for various uses. It adds to the chemical industry and does not live up to the research and development and production efforts.

Preparation Method

The method of making 2 - Amino - 4 - Fluoro - 1 - Methoxybenzene is essential for raw materials and processes. First, take an appropriate amount of fluorobenzene, and introduce the methoxy group by methoxylation. This step requires temperature control and reaction time to achieve accurate conversion. Following the amination technique, the target amino group is generated, and the reaction conditions must be rigorous to prevent side reactions.
In the preparation, the proportion of raw materials, reaction rate and catalyst effectiveness are all about success or failure. The purity of raw materials and the refinement of the process are the basis of quality. After the reaction is completed, it is purified and refined to remove impurities and obtain a pure product.
Its preparation mechanism is based on the principle of organic chemistry, and each step of the reaction complements each other. After these steps, according to the precise method, 2-Amino-4-Fluoro-1-Methoxybenzene can be obtained, which may be of great use in the field of chemical medicine.

Chemical Reactions & Modifications

2-Amino-4-fluoro-1-methoxybenzene, the chemical reaction and modification of this compound is the focus of our chemical researchers. The way of its reaction is related to many chemical mechanisms. In the past, common reaction paths or substitution methods were studied to achieve the purpose of modification. Fluorine, amino, and methoxy groups have their own uses in the reaction. Fluorine, which has strong electronegativity, can cause the density of the electron cloud to change, which affects the reactivity. Amino is also an active group and can attract electrophilic reagents. Methoxy has the effect of an electron generator and can help the reaction go in a specific direction. We want to obtain the better properties of this compound, and observe its changes under changing reaction conditions, such as adjusting temperature and changing solvent. After many attempts, we hope to find the most suitable reaction method to make this compound have excellent properties and are useful in chemical, pharmaceutical and other industries.

Synonyms & Product Names

2-Amino-4-fluoro-1-methoxybenzene is really an important thing in the study of chemistry. Its aliases and trade names are also of exquisite value.
Looking at this substance, there are many aliases, which all stem from the variety of chemical naming rules and the customary names in different research situations. As for the trade name, it is given by the merchant in the market circulation to highlight its characteristics or uses, so as to distinguish it from others.
The existence of aliases makes academic communication more accurate, and can choose suitable names according to different theoretical and experimental needs. Trade names are related to marketing activities, allowing users to quickly identify their advantages and application areas. For example, in the field of chemical synthesis, knowing its many aliases can be understood in the literature and operated accurately; in commercial applications, familiar with trade names can be purchased on demand. The study of this alias and trade names is indispensable for the research and application of 2-amino-4-fluoro-1-methoxybenzene.

Safety & Operational Standards

2 - Amino - 4 - Fluoro - 1 - Methoxybenzene is an important chemical. During its production and use, safety and operating practices are of paramount importance.
First words are safe. This substance may be toxic and irritating to a certain extent. Be sure to take protective measures when exposed. The experimenter wears protective clothing, protective gloves, and goggles on the face to prevent possible splashing. Operate in a well-ventilated place to prevent the accumulation of harmful gases. If inhaled inadvertently, move to a fresh air place quickly. If symptoms are serious, seek medical attention immediately. If the skin comes into contact, rinse with plenty of water immediately.
In terms of operating specifications, the use of this substance requires a precise measuring tool to ensure that the dosage is accurate to meet the requirements of experiments or production. Its storage should also be cautious, and it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent dangerous reactions. During the reaction process, the reaction conditions, such as temperature, pressure and reaction time, should be strictly controlled, and the operation should be carried out according to the established process. No unauthorized changes should be made. The reaction equipment needs to be checked regularly to ensure its tightness and safety to prevent leakage.
In conclusion, the safety and operation standards of 2-Amino-4-Fluoro-1-Methoxybenzene must not be neglected. This is related to the safety of the experimenter and the smooth production process. Only by strictly adhering to the regulations can accidents be avoided and related work can be carried out in an orderly manner.

Application Area

2-Amino-4-fluoro-1-methoxybenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical research and development, this compound may be a key intermediate. With its unique structure, it can help synthesize specific drugs to treat various diseases, such as analgesic and anti-inflammatory drugs, or rely on it to build a molecular framework to achieve precise curative effect.
In the field of materials science, it can also be used. Or can participate in the creation of new functional materials, if they have special optical and electrical properties. With its chemical properties, the structure and properties of the material can be adjusted, opening up a path for the research and development of new materials.
Furthermore, in the fine chemical industry, 2-amino-4-fluoro-1-methoxybenzene can be used to prepare high-end chemicals and additives. The characteristics of the product, such as improving the durability of coatings and improving the stability of plastics, depend on this. Its applications in various fields show extraordinary potential, injecting vitality into scientific research and industrial development.

Research & Development

In recent years, I have developed a new product in the field of chemistry, named 2 - Amino - 4 - Fluoro - 1 - Methoxybenzene. The research of this product has gone through many twists and turns. At the beginning, the selection of raw materials is quite laborious, and it must be pure and suitable. The reaction bar, temperature, pressure, catalyst, etc., are all explored in detail.
In order to obtain the best effect, test it repeatedly, observe its changes, and record its data. Every time there is a difference, the reason will be carefully investigated, and the method will be changed and tried again. Fortunately, the quality of the product has gradually improved.
The research is endless, and I want to expand its use in the future. Thinking of this product in the fields of medicine, materials, etc., it may be possible. With unremitting research, make it widely spread, advance in the industry, and benefit the world, and promote the development of this new chemical product to a higher level.

Toxicity Research

The toxicity of 2 - Amino - 4 - Fluoro - 1 - Methoxybenzene is a matter of crucial importance. Looking at the structure of this compound, it contains fluorine, methoxy and amino groups. Although fluorine has unique properties in many compounds, some fluorine-containing substances may have potential toxicity. The existence of methoxy groups may affect its fat solubility and metabolic pathways, which in turn is related to toxicity. Amino groups may participate in biochemical reactions in vivo and change their biological activities.
After a series of experiments, in a specific cell model, a certain concentration of this compound can cause a decrease in cell viability, which is dose-dependent. Or interfere with key metabolic pathways in cells and affect normal physiological functions of cells. According to animal experiments, after ingesting this compound, some physiological indicators of animals are abnormal. However, toxicity research still needs to be in-depth, considering its metabolic transformation in different biological systems and the potential impact of long-term exposure, in order to clarify its exact toxicity, and lay the foundation for subsequent application and security evaluation.

Future Prospects

I try to research chemical products, and I have high hopes for this product of 2 - Amino - 4 - Fluoro - 1 - Methoxybenzene. Looking at the current situation, although the synthesis process of this product has achieved small success, it still needs to be refined.
In the future, the synthesis of this product will be more accurate, impurities can be greatly reduced, and the yield will also be significantly improved. In the field of medicine, this product may be used as a key intermediate to help the development of new drugs and solve the pain of patients. In materials science, it is also expected to lay the foundation for the creation of new materials and open up new applications.
In time, when more scientific researchers are dedicated to this, their unlimited potential will be explored together. I firmly believe that the future of 2 - Amino - 4 - Fluoro - 1 - Methoxybenzene will be like the rising sun, shining brightly for the chemical industry and seeking endless benefits for human well-being.

Where to Buy 2-Amino-4-Fluoro-1-Methoxybenzene in China?

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Frequently Asked Questions

As a leading 2-Amino-4-Fluoro-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Amino-4-Fluoro-1-Methoxybenzene?

2-Amino-4-fluoro-1-methoxybenzene is widely used. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many drugs. The unique chemical properties of amino groups, fluorine atoms and methoxy groups in the molecule give it the potential to interact with biological targets. For example, through organic synthesis, it can be modified to develop therapeutic drugs for specific diseases, or play an important role in the creation of antibacterial and antiviral drugs.
In the field of materials science, it also has outstanding performance. With its unique chemical structure, materials with special optoelectronic properties can be prepared through a series of reactions. For example, as a basic unit for the construction of organic Light Emitting Diode (OLED) materials, it helps to improve the luminous efficiency and stability of materials, and contributes to the development of display technology.
In the field of pesticide chemistry, 2-amino-4-fluoro-1-methoxybenzene also plays an important role. Pesticide compounds with high insecticidal, bactericidal or herbicidal activities can be derived through rational design and modification, and because of their special structure, they are expected to achieve precise effects on specific target organisms and reduce the impact on the environment and non-target organisms. In conclusion, the unique chemical structure of 2-amino-4-fluoro-1-methoxybenzene is indispensable in many important fields.

What are the physical properties of 2-Amino-4-Fluoro-1-Methoxybenzene?

2-Amino-4-fluoro-1-methoxybenzene is one of the organic compounds. Its physical properties are quite elusive.
Looking at its properties, it is mostly solid at room temperature and pressure, or white to light yellow crystalline powder. This is due to the characteristics of its molecular structure, and the intermolecular force allows the substance to exist stably in the solid state.
As for the melting point, it is about a specific temperature range. The force of intermolecular interaction determines the melting point. When the energy provided by the outside world is sufficient to overcome this interaction, the molecule can break free from the lattice binding and melt.
Boiling point also has corresponding values. At this temperature, the molecule is energized enough to break free from the shackles of the liquid state and become a gaseous state to escape. The value of this boiling point is determined by factors such as intermolecular forces and relative molecular weights.
In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether. Due to the principle of "similar miscibility", the structure of the compound can form interactions such as van der Waals force and hydrogen bond between organic solvent molecules, so that it can be dispersed in organic solvents. However, in water, the solubility is relatively limited. Due to the poor matching of molecular polarity with water molecule polarity, it is difficult to form effective interactions, so it is difficult to dissolve in water.
Density is also one of its important physical properties. The value of its density reflects the mass of the substance per unit volume, and is related to the degree of close accumulation of molecules and the relative molecular weight. The characteristics of this density have a significant impact on the separation and mixing of substances.
In summary, the physical properties of 2-amino-4-fluoro-1-methoxybenzene, such as properties, melting point, boiling point, solubility, density, etc., are determined by its molecular structure and are of great significance in chemical research and practical applications.

Is 2-Amino-4-Fluoro-1-Methoxybenzene chemically stable?

2-Amino-4-fluoro-1-methoxybenzene, this is an organic compound. The stability of its chemical properties depends on many factors.
Looking at its structure, the amino group has electron donor property, which can increase the electron cloud density of the benzene ring, and cause the benzene ring to be more prone to electrophilic substitution reaction, which may affect its stability to a certain extent. Although the fluorine atom has strong electronegativity and has an electron-absorbing induction effect on the benzene ring, it has a solitary pair electron, and there is also an electron conjugation effect. The coexistence of the two effects also plays an role in the stability of the compound. Methoxy group is a donor electron group, which can also increase the electron cloud density of the benzene ring and improve the electrophilic reaction activity of the ben
Under normal conditions, the compound may remain relatively stable without the influence of specific reagents or external factors. However, in case of strong oxidants, strong acids, strong bases and other reagents, or under special conditions such as high temperature and light, its stability may be destroyed.
Strong oxidants or cause oxidation of amino groups, methoxy groups and other groups, changing the structure of the compound. In strong acid and strong base environments, amino groups, methoxy groups, etc. may undergo protonation, hydrolysis and other reactions. High temperature, light may also trigger intramolecular rearrangement, free radical reactions, etc., which change their chemical properties and reduce their stability.
In conclusion, the stability of 2-amino-4-fluoro-1-methoxybenzene is not static, but is closely related to the environment and contact substances.

What are 2-Amino-4-Fluoro-1-Methoxybenzene synthesis methods?

There are several common methods for the synthesis of 2-amino-4-fluoro-1-methoxybenzene.
First, 2-methoxy-5-fluoroaniline is used as the starting material. The amino group is protected by a specific protective group to prevent it from interfering in subsequent reactions. After that, through a halogenation reaction, the desired halogen atom is introduced, and then through a substitution reaction, the halogen atom is replaced by a methoxy group, and the protective group is finally removed to obtain the target product 2-amino-4-fluoro-1-methoxybenzene. This path requires careful selection of protective groups and reaction conditions so that each step of the reaction can proceed smoothly.
Second, 4-fluoro-1-methoxy-2-nitrobenzene is used as the starting material. Using a reducing agent, such as the combination of iron, zinc and hydrochloric acid, or catalytic hydrogenation, the nitro group is reduced to an amino group to obtain 2-amino-4-fluoro-1-methoxylbenzene. The key to this method is to control the conditions of the reduction reaction, to avoid excessive reduction or other side reactions that affect the purity and yield of the product.
Third, the Grignard reagent method can be used. Using suitable halogenated aromatics as the starting material, react with magnesium to form Grignard reagents. Then the Grignard reagent is reacted with a suitable compound containing fluorine and methoxy to build the skeleton of the target molecule, and then through a suitable conversion reaction, 2-amino-4-fluoro-1-methoxylbenzene is generated. In this process, the preparation of Grignard reagent and the control of reaction conditions are quite important, and it is necessary to operate in an anhydrous and anaerobic environment to prevent the decomposition of Grignard reagent.
Each synthesis method has its own advantages and disadvantages. It is necessary to comprehensively consider the actual needs, such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the product, to choose the most suitable synthesis path.

What is the price range of 2-Amino-4-Fluoro-1-Methoxybenzene in the market?

2-Amino-4-fluoro-1-methoxybenzene is in the market, and its price range is difficult to determine. According to Guanfu's "Tiangong Kaiwu", the price of various things often varies according to time, place, and supply and demand. The same is true for this 2-amino-4-fluoro-1-methoxybenzene.
If the price of various materials in the past is not constant. Or due to the distance of the place of origin, the cost of transportation is different, and the price is also different. If the product is close, the price may be slightly cheaper; if the product is far away, add the freight, and the price will increase.
Due to the trend of supply and demand, if there are many people in the market who need this 2-amino-4-fluoro-1-methoxybenzene, and the supply is small, the price will increase; if the supply exceeds the demand, the price will be self-suppressing.
And the difficulty of making this product is also related to its price. If the production method is difficult and requires a lot of materials and working hours, the cost will be high, and the price will be high; if the production method is simple, the cost will decrease, and the price may be lower.
However, I do not have the exact number, and it is difficult to know the specific price. However, based on common sense, its price may fluctuate between markets due to the above-mentioned reasons, or range from tens of yuan per kilogram to hundreds of yuan per kilogram. However, this is only an idea. The actual price shall be subject to the current market conditions.