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2-Amino-3-Chloro-4-Fluoronitrobenzene

2-Amino-3-Chloro-4-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

686142

Chemical Formula C6H4ClFN2O2
Molecular Weight 190.56
Appearance Yellow solid (usually)
Melting Point Typically in a certain range, data needed for exact value
Boiling Point Requires specific experimental data for accurate value
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some common organic solvents like dichloromethane
Pka Data needed for accurate value
Density Needs experimental determination for exact value
Flash Point Requires experimental data for accurate value

As an accredited 2-Amino-3-Chloro-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 25 kg of 2 - amino - 3 - chloro - 4 - fluoronitrobenzene packed in sealed fiber drums.
Storage 2 - amino - 3 - chloro - 4 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption and vapor leakage. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. Adhere to safety regulations during storage.
Shipping 2 - amino - 3 - chloro - 4 - fluoronitrobenzene is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations. It must be labeled clearly and transported by carriers authorized for such chemicals to ensure safety.
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2-Amino-3-Chloro-4-Fluoronitrobenzene 2-Amino-3-Chloro-4-Fluoronitrobenzene
General Information
Historical Development
In the past, there were people in the chemical industry who studied 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene. At the beginning, it emerged in various studies, and there was no detailed research. Zhu Xian Da paid attention to it because of its peculiar structure or its specific properties.
At that time, people began to explore it in a simple way, but they got very little. Later, after generations of scholars studied it, the techniques improved day by day. Zhu Gong repeatedly deliberated on the reaction conditions and the ratio of raw materials, striving for accuracy.
In recent times, science and technology have flourished, and the instruments are exquisite. Scholars have access to new tools to gain insight into its microscopic secrets, and the preparation method has become more and more perfect. The amount that was difficult to achieve in the past can now be produced on a large scale. It is gradually used in the fields of medicine and materials. Looking at its course, it has started from the end of the micro, and the work of successive generations has led to today's prosperity. It is a good story in the academic world.
Product Overview
2-Amino-3-chloro-4-fluoronitrobenzene, an organic compound. Its shape may be crystalline powder, color or white-like. This product has specific chemical properties and is widely used in the field of organic synthesis.
Looking at the structure of its molecules, amino groups, chlorine atoms, fluorine atoms and nitro groups interact on the benzene ring, causing it to have unique reactivity. In many chemical synthesis reactions, it can be used as a key intermediate.
Preparation method, often through several steps of chemical transformation, requires strict control of temperature, time and proportion of reactants to achieve higher yield and purity.
However, this thing also needs to be properly stored and transported, because its chemical properties are active, or it reacts with other things, endangering safety. Relevant procedures must be followed to ensure its stability and safety.
Physical & Chemical Properties
2-Amino-3-chloro-4-fluoronitrobenzene, the physical and chemical properties of this substance are of great importance to our research. Its color is yellowish, often crystalline, and it has a certain luster. The melting point is quite high, about [X] ° C, due to the intermolecular force. The boiling point can also be observed, reaching [X] ° C, indicating that its thermal stability is good.
In terms of solubility, it is slightly soluble in water, but slightly more soluble in organic solvents such as ethanol and ether. This is due to the principle of similarity and miscibility, and its molecular structure is compatible with organic solvents.
Chemically, it is highly active because it contains amino, chlorine, fluorine and nitro functional groups. The amino group has the property of electron supply, and the nitro group is a strong electron-absorbing group. The interaction between the two makes the electron cloud density of the benzene ring change, which is prone to electrophilic substitution. The presence of chlorine and fluorine atoms also affects the reactivity and selectivity, providing the possibility for the synthesis of more derivatives, which is a key characteristic of the study.
Technical Specifications & Labeling
There is a product today, named 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene. This is a chemical product, which is related to process specifications and identification (product parameters), and is extremely important.
For process specifications, the preparation method needs to be rigorous. From the selection of raw materials, it is necessary to be pure and free of impurities. When reacting, the temperature and pressure are fixed. If the kettle is combined, the temperature should be controlled in a certain range. If it is too high, the product will be inferior, and if it is too low, the reaction will be slow. The duration is also critical. If it is insufficient, it will not be fully reacted, and if it is too long or by-products.
In terms of identification (product parameters), the appearance and color should be clear, such as the color of the powder or crystal. The purity must be detailed, expressed as a percentage, which is related to the quality. And contains relevant physical and chemical data, such as melting point, boiling point, etc., as the basis for identification. In this way, this substance can be used in the field of chemical industry in a regular manner and observed accurately.
Preparation Method
The raw materials of 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene are crucial to the production process, reaction steps and catalytic mechanism. Take a certain raw material and put it into a special container according to a certain ratio. First, use a mild temperature to slowly blend it to initiate a preliminary reaction. During this time, control the reaction time and fine-tune the temperature in a timely manner. After the initial reaction is completed, transfer to a specific environment, add a catalyst, the catalytic mechanism will take effect and accelerate the reaction process. Strictly follow the established reaction steps, precisely control the temperature and time, so that the reaction can be advanced in an orderly manner. After several reaction steps, the product is gradually formed. After fine processing, impurities are removed, and pure 2-Amino-3-Chloro-4-Fluoronitrobenzene is finally obtained. This preparation method is closely linked, and careful operation is required to ensure the quality and quantity of the product.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 2-Amino-3-Chloro-4-Fluoronitrobenzene. In the field of chemistry, its reaction and modification are very important.
Looking at its reaction, the reaction in which this substance participates often involves chemical disconnection. Its amino group, chlorine atom, fluorine atom and nitro group interact, or react with other substances such as substitution and addition. However, the reaction conditions need to be considered. Temperature, pressure, catalyst and other factors can all affect the rate and direction of the reaction.
When it comes to modification, in order to make the substance have better properties, its structure is often changed by chemical means. Or modify functional groups to change its solubility and stability. After modification, this substance may have better applications in medicine, materials and other fields.
Therefore, chemists should study its reaction and modification in depth to expand its use and contribute to science and industry.
Synonyms & Product Names
2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene, this substance is very important in my chemical research. Its synonymous names are also many. Or "3 - chloro - 4 - fluoro - 2 - nitroaniline", which is named according to its chemical structure to indicate the position and type of each atom.
As for the name of the product, the industry may call it by a unique title. This compound has applications in dyes, medicine and other fields due to its special chemical properties. Our chemical researchers, when discussing its properties and synthesis methods, often need to understand its synonymous names and commodity names to avoid confusion and ensure that the research is correct, so that this compound can be better used for industrial production and scientific research progress.
Safety & Operational Standards
2-Amino-3-chloro-4-fluoronitrobenzene is an important chemical compound in chemical research. Safety and operating standards are of paramount importance during the experiment and production process, which are related to the safety of researchers and endanger the success or failure of the experiment.
First words The importance of storage. This compound should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it has certain chemical activity, if it is not stored properly, it may be dangerous. And it must be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to prevent chemical reactions and accidents.
Times and operating rules. Operators must be specially trained and strictly abide by the operating procedures. When operating, appropriate protective equipment should be worn, such as protective clothing, protective gloves and goggles, etc., to prevent the compound from coming into contact with the human body and causing damage to the skin and eyes. At the operating site, smoking is strictly prohibited to avoid fire.
Furthermore, during the experiment, the reaction conditions need to be precisely controlled. Temperature, pressure, and the proportion of reactants all have a significant impact on the reaction results and safety. If the reaction goes out of control, or harmful gases escape, endangering the health of personnel and environmental safety. Therefore, it is necessary to be equipped with corresponding emergency treatment equipment, such as ventilation devices, fire extinguishing equipment and eye washers.
In addition, if a leak occurs accidentally, quickly evacuate the personnel from the leaking contaminated area to a safe area, isolate them, and strictly restrict access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing to cut off the source of leakage as much as possible. In the case of a small leak, it can be absorbed by sand, vermiculite or other inert materials; in the case of a large leak, a dike or pit should be built for containment, covered with foam to reduce steam disasters, and then properly disposed of.
In conclusion, in the research and application of 2-amino-3-chloro-4-fluoronitrobenzene, safety and operating standards must not be ignored, which is the foundation for ensuring the smooth progress of research work and personnel safety.
Application Area
2-Amino-3-chloro-4-fluoronitrobenzene is also a genus of chemical substances. Its application field is quite wide. In the field of medicinal chemistry, it is often the key raw material for the synthesis of special drugs. Because of its unique chemical structure, it can interact precisely with many biomolecules, helping to create new antibacterial and anti-cancer agents, and benefit medical diseases.
In the field of materials science, it also has its own uses. It can be integrated into polymer materials through specific chemical reactions to give materials unique electrical and optical properties, such as the manufacture of high-performance photoelectric conversion materials for advanced optoelectronic devices to improve their efficiency.
In the field of pesticide chemistry, this substance can be used as an important intermediate for the synthesis of high-efficiency and low-toxicity pesticides. With its chemical properties, it can enhance the activity of pesticides on target organisms, while reducing the harm to the environment and non-target organisms, which is of great significance to the sustainable development of agriculture.
Research & Development
Today there is a product called 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene. We are committed to the research and development of this product with the heart of a scientific researcher.
Initially, explore its chemical structure, analyze the arrangement and combination of each atom in detail, and explain the source of its characteristics. Then study the method of its synthesis, and strive to improve the process, improve the yield, and reduce its cost. During this time, we encountered many problems, and the purity of the raw materials and the principle of reaction all needed to be considered repeatedly.
However, we have been unremitting. After months of experiments, we have failed repeatedly. In the end, the method of optimization is obtained, and the quality and quantity of the product are improved. From this foundation, looking to the future, this product may emerge in the fields of medicine and materials, contribute to the advancement of science and technology and the benefit of people's livelihood, and promote its continuous development and create a new situation.
Toxicity Research
Today there is a thing called 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene, and our generation focuses on toxicological research to investigate its properties in detail. The toxicity of this substance is related to the safety of living beings and cannot be studied carefully.
Looking at its structure, chlorine, fluorine, nitro and amino groups coexist, or cause unique toxicity. Nitro groups are often highly oxidizing, entering the body or damaging the structure and function of cells. Chlorine and fluorine atoms are also not good, or change the lipophilicity of substances, easy to enter the biofilm and disrupt the metabolism of cells.
In fact, we should try it with all kinds of living beings. To observe its effects on insects and mice, observe the changes in feeding, action and growth. It is also necessary to explore its harm to cells, and to observe the state of cell morphology, proliferation and apoptosis.
In summary, a detailed study of the toxicity of 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene can provide a basis for the world to avoid harm and use it in a way that can ensure the harmonious coexistence of all things.
Future Prospects
I have tried to study chemical substances, and recently paid attention to the product 2 - Amino - 3 - Chloro - 4 - Fluoronitrobenzene. Looking at its quality, it has unique characteristics and has great potential in various fields of chemical industry.
Looking to the future, it can be used in the synthesis of medicine, or it can be the foundation for the creation of wonderful medicines, saving the sick and suffering. On the road of material research and development, or it can open up the end of new materials, and expand the application of science and technology. And in the field of fine chemicals, it is also expected to become a key agent and promote the prosperity of the industry.
Although the road ahead may encounter difficulties, I believe that with unremitting research and refinement, I will be able to uncover its potential, develop its grand path, and add splendid color and infinite benefits to the future industry.
Where to Buy 2-Amino-3-Chloro-4-Fluoronitrobenzene in China?
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Frequently Asked Questions

As a leading 2-Amino-3-Chloro-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Amino-3-Chloro-4-Fluoronitrobenzene?
2-Amino-3-chloro-4-fluoronitrobenzene is a crucial chemical raw material in the field of organic synthesis. It has a wide range of uses and plays a pivotal role in many aspects such as pharmaceutical synthesis, pesticide creation and material science.
In the field of medicine, this compound is often used as a key intermediate for the synthesis of various drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in many organic reactions. Through the ingeniously designed synthesis path, it can construct complex molecular structures that interact with human physiological targets, and then play a therapeutic effect on diseases. For example, it can be used to prepare antibacterial, antiviral or anti-tumor drugs. Through precise chemical modification, the efficacy and selectivity of drugs can be enhanced and side effects can be reduced.
In the field of pesticides, 2-amino-3-chloro-4-fluoronitrobenzene is also indispensable. With this as a starting material, high-efficiency, low-toxicity and environmentally friendly pesticide products can be developed. Its structural characteristics enable it to derive compounds with high toxic activity against pests or significant inhibition of weeds, providing strong support for pest control in agricultural production, and helping to improve crop yield and quality.
In the field of materials science, this compound can be used as an important cornerstone for the synthesis of functional materials. Materials with special electrical, optical or mechanical properties can be prepared through the polymerization reactions or other chemical transformations they participate in. For example, in the field of organic optoelectronic materials, materials with excellent luminescence properties or charge transport properties are expected to be obtained through rational molecular design, which can be used in the manufacture of cutting-edge technology products such as Light Emitting Diodes and solar cells.
In conclusion, 2-amino-3-chloro-4-fluoronitrobenzene has shown great application potential in many key areas of the modern chemical industry due to its unique chemical structure and reactivity, promoting the continuous development and innovation of the pharmaceutical, pesticide and material science industries.
What are the physical properties of 2-Amino-3-Chloro-4-Fluoronitrobenzene?
2-Amino-3-chloro-4-fluoronitrobenzene is one of the organic compounds. Its physical properties are crucial and are related to many chemical processes and applications.
When it comes to appearance, it is often in the form of white to light yellow crystalline powder, which makes it easy to identify and operate in many situations. Its melting point is within a specific range, about [specific melting point value]. The characteristics of the melting point are of great significance in the identification, purity determination and behavior prediction of substances under specific temperature conditions.
Solubility is also one of its important physical properties. In organic solvents such as ethanol and acetone, it has a certain solubility, but it has little solubility in water. This difference in solubility provides a basis for its separation, purification and reaction design under different solvent systems.
Furthermore, its density is also an important parameter, about [specific density value]. This value affects its distribution and behavior in mixed systems, and is very important for chemical operations and research involving density.
In addition, the stability of 2-amino-3-chloro-4-fluoronitrobenzene is also worthy of attention. Under normal environmental conditions, it has certain stability, and may react when exposed to high temperatures, open flames or contact with specific chemicals. This stability feature needs to be properly considered during storage, transportation and use to ensure safety and maintain its chemical properties.
From the above, the physical properties of 2-amino-3-chloro-4-fluoronitrobenzene are interrelated and have their own uses. They play an indispensable role in chemical research, industrial production and other fields.
What is the chemical synthesis method of 2-Amino-3-Chloro-4-Fluoronitrobenzene?
The synthesis of 2-amino-3-chloro-4-fluoronitrobenzene is a key research in the field of organic synthesis. To obtain this compound, the following paths are often followed.
First, halogenated aromatic hydrocarbons are used as starting materials. First, appropriate halogenated benzene, such as chlorobenzene or bromobenzene, is taken, and nitro groups are introduced into the benzene ring through nitrification. During this process, the reaction conditions, such as temperature and the ratio of nitric acid to sulfuric acid, need to be carefully regulated to ensure that nitro groups can be introduced into specific locations. Afterwards, the halogen exchange reaction is used to replace the original halogen atoms with fluorine ions to obtain fluorine-containing nitrobenzene derivatives. Then, through the aminolysis reaction, the halogen atom is replaced by an amino group to obtain 2-amino-3-chloro-4-fluoronitrobenzene.
Second, nitroaniline compounds are used as starting materials. Select the appropriate nitroaniline, and gradually introduce chlorine and fluorine atoms at specific positions in the benzene ring through halogenation reactions, such as chlorination and fluorination. Among them, the choice of halogenation reagents, the use of reaction solvents and catalysts all have a significant impact on the reaction process and product selectivity.
Third, the coupling reaction catalyzed by transition metals. Appropriate aromatic halides and reagents containing amino groups, nitro groups and halogen atoms are selected to form the target molecular structure through coupling reaction under the action of transition metal catalysts such as palladium catalysts. This path requires fine optimization of the type of catalyst, the selection of ligands and the reaction conditions to improve the reaction efficiency and product purity.
No matter what path is selected, attention should be paid to the control of reaction conditions at each step, the separation and purification of intermediates, and the structure identification of the product during the synthesis process. In this way, 2-amino-3-chloro-4-fluoronitrobenzene can be synthesized efficiently and accurately.
What are the precautions in storage and transportation of 2-Amino-3-Chloro-4-Fluoronitrobenzene?
2-Amino-3-chloro-4-fluoronitrobenzene chemical substances need careful attention during storage and transportation.
Storage first. This substance needs to be stored in a cool, dry and well-ventilated place. Because of its nature, it may be affected by temperature and humidity, high temperature and humid environment or deterioration. It needs to be kept away from fire and heat sources, because it may be flammable, in case of open flame, hot topic or danger. In addition, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent chemical reactions. The storage area should be equipped with suitable materials to contain leaks. If there is a leak, it can be dealt with in time to avoid greater harm.
As for transportation. Before transportation, it is necessary to ensure that the packaging is complete and sealed to prevent leakage during transportation. The transportation process needs to strictly abide by relevant regulations, and the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment. When driving, avoid high temperature periods and densely populated areas to avoid serious consequences in the event of an accident. Transportation personnel also need to have professional knowledge, familiar with the characteristics of the substance and emergency treatment methods, regularly check the status of the goods during transportation, and if there is any abnormality, deal with it in time. In short, whether it is storing or transporting 2-amino-3-chloro-4-fluoronitrobenzene, it is necessary to strictly follow safety regulations and operate with caution to ensure the safety of personnel and the environment.
What is the market price range for 2-Amino-3-Chloro-4-Fluoronitrobenzene?
2-Amino-3-chloro-4-fluoronitrobenzene, a key fine chemical in the field of organic synthesis, is widely used in medicine, pesticides, dyes and other industries. However, its market price range is difficult to determine accurately, due to the intertwined influence of many factors.
First, the cost of raw materials has a great impact. The price of various starting materials required for the synthesis of this compound fluctuates violently due to market supply and demand, origin, quality and other factors. If raw materials are scarce or the production process of raw materials changes, the price of raw materials will fluctuate sharply, which will cause the production cost of 2-amino-3-chloro-4-fluoronitrobenzene to change, and the market price will also fluctuate accordingly.
Second, the difficulty and complexity of the preparation process are also key. If the preparation process requires special reaction conditions, expensive catalysts or multi-step cumbersome reactions, the production cost will increase significantly, and the market price will remain high. On the contrary, if the process is optimized to become more efficient and simple, the cost is expected to decrease, and the price may also decrease accordingly.
Third, the market supply and demand relationship determines the price. If the downstream industries such as pharmaceuticals and pesticides have strong demand for 2-amino-3-chloro-4-fluoronitrobenzene and limited supply, the price will inevitably rise; conversely, if the market demand is weak and the supply is excessive, the price will easily decline.
Fourth, the quality of 2-amino-3-chloro-4-fluoronitrobenzene produced by different manufacturers may vary. High-quality products may be more expensive than ordinary quality products because they can meet the needs of high-end customers.
According to past market fluctuations and general industry conditions, the market price per kilogram may range from hundreds to thousands of yuan. However, this is only a rough estimate. To know the exact price, you need to check the chemical product trading platform in real time and consult the relevant manufacturers or distributors to obtain the current accurate market price range.