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2,6-Difluorobenzenesulfonyl Chloride

2,6-Difluorobenzenesulfonyl Chloride

Hongda Chemical

Specifications

HS Code

905360

Chemical Formula C6H3ClF2O2S
Molecular Weight 226.602 g/mol
Appearance Typically a colorless to pale - yellow liquid
Odor Pungent odor
Density Data may vary, but around 1.6 g/cm³
Boiling Point Approximately 240 - 245 °C
Solubility Soluble in many organic solvents like dichloromethane, toluene
Reactivity Highly reactive towards nucleophiles, reacts with alcohols, amines
Hazard Class Corrosive, causes burns to skin and eyes

As an accredited 2,6-Difluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,6 - difluorobenzenesulfonyl chloride packaged in a sealed glass bottle.
Storage 2,6 - difluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent contact with moisture, as it is reactive to water. Store it separately from incompatible substances like bases and reducing agents to avoid potential chemical reactions.
Shipping 2,6 - difluorobenzenesulfonyl chloride is a chemical that may require special shipping precautions. It should be packaged in corrosion - resistant containers, labeled properly, and shipped in accordance with hazardous materials regulations to ensure safety during transit.
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2,6-Difluorobenzenesulfonyl Chloride 2,6-Difluorobenzenesulfonyl Chloride
General Information
Historical Development
2,6-Difluorobenzenesulfonyl chloride is also a genus of chemical products. Looking at the historical development of its products, at the beginning of research and development in the past, chemists devoted themselves to the exploration of new compounds and studied sulfonyl chloride derivatives. Although the technology at that time was limited, the ambition was unremitting.
The initial synthesis process was complicated and the yield was low. After various attempts, the reaction conditions were improved and the ratio of raw materials was adjusted. With the advancement of science and technology, the catalytic system was optimized, the reaction efficiency increased, and the yield gradually increased. From the preparation of niche products in the laboratory to the production of industrial scale, this process has been difficult and fruitful. The difficulties of the past have now been resolved. 2,6-difluorobenzenesulfonyl chloride is widely used in the chemical industry, which can be described as one of the great witnesses of chemical development, and it is expected to show more potential in the future.
Product Overview
The product description of 2,6-difluorobenzenesulfonyl chloride
Fu 2,6-difluorobenzenesulfonyl chloride is a crucial chemical reagent in the field of organic synthesis. It is a colorless to slightly yellow liquid with a pungent smell and is volatile in the air.
The preparation of this substance is often obtained through specific fluorination and sulfonyl chloride reactions. The reaction conditions need to be precisely controlled, and the temperature, reagent ratio and reaction time all have a great impact on the purity and yield of the product.
2,6-difluorobenzenesulfonyl chloride is widely used in fine chemical industries such as medicine and pesticides. In pharmaceutical synthesis, it can be used as a key intermediate to participate in the construction of a variety of drug molecules and help develop new specific drugs. In the field of pesticides, it can be used to create high-efficiency, low-toxicity and environmentally friendly pesticide varieties to escort agricultural production.
However, this material is corrosive and irritating to a certain extent. When operating, it is necessary to strictly abide by safety procedures, wear complete protective equipment, and conduct it in a well-ventilated place. Storage should also be cautious. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent accidents.
Physical & Chemical Properties
There is a substance named 2,6-difluorobenzenesulfonyl chloride. Its physical properties are also colorless to slightly yellow liquid at room temperature, with a pungent odor, which is known by the senses. Its boiling point can quite reflect its thermodynamic properties, which are about a certain temperature range, due to the intermolecular forces. Its melting point is also characteristic, and this value is related to the phase transition of substances.
From a chemical point of view, 2,6-difluorobenzenesulfonyl chloride contains sulfonyl chloride groups and has active chemical properties. It can react with alcohols to form sulfonates; when it interacts with amines, it can obtain sulfonamides. This is all due to the electrophilicity of sulfonyl chloride groups, which can be substituted with electron-rich groups under suitable conditions. Its chemical activity makes it useful in the field of organic synthesis, such as drug and material synthesis, and it is an indispensable raw material for chemical research and industrial production.
Technical Specifications & Labeling
2,6-Difluorobenzenesulfonyl chloride is an important product in the chemical industry. Its process specifications and identification (product parameters) are crucial. The preparation of this product requires a precise method, and the selection of raw materials and the control of reaction conditions are determined.
In terms of process specifications, the reaction temperature needs to be stable in a specific range, and the material ratio must follow an accurate number, so as to ensure the purity and yield of the product. The reaction time should also be appropriate. If it is too short, the reaction will not be completed, and if it is too long or cause side reactions.
In terms of identification, the product parameters should be clearly marked, such as the purity geometry and impurity content, which should be detailed, so that the user can understand the chest, so as not to have the risk of misuse, so as to achieve the purpose of safe and efficient use.
Preparation Method
The method of making 2,6-difluorobenzene sulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials, when taken from pure materials, such as difluorobenzene and sulfonation reagents, ensure that the texture is fine and there are no impurities.
In the production process, the difluorobenzene is first placed in the reaction kettle, and the sulfonating reagent is added in sequence. The temperature is controlled in a suitable environment, and it should not be too dramatic or too slow. The reaction steps are rigorous. Stir evenly at the beginning to make the materials fully blend, and then heat up to initiate the reaction. Close inspection of the reaction state and fine-tuning the conditions according to its process.
Catalytic mechanism, select the appropriate catalyst to promote the reaction to speed up and improve the yield. The amount of catalyst input needs to be weighed accurately, and too much or too little will affect the results. In this way, the method of preparing 2,6-difluorobenzenesulfonyl chloride can obtain high-quality products, which are also important in the chemical industry.
Chemical Reactions & Modifications
Guanfu 2, 6 - Difluorobenzenesulfonyl Chloride This substance is related to the change of physical properties. As for the reaction of this compound, the clutch of chemical bonds and the rearrangement of atoms all have their own rules.
If you want to do something good, you must observe the conditions of its reaction. The temperature, the acid and base of the medium, can affect its reaction. And the rate of reaction is also the key. Whether you want to speed it up or stabilize it, it depends on the precise control of the conditions.
As for the change of chemical properties, it is to make this substance suitable for various scenarios. Increasing or decreasing its activity and changing its hydrophilic and hydrophobic properties can be done by borrowing. By modifying its structure and introducing new groups, it can give it different energy. This is all the hard work of chemical researchers, hoping to adapt to the ingenuity and obtain the changeability of physical properties, and open up new avenues for various practical applications.
Synonyms & Product Names
2,6-Difluorobenzenesulfonyl chloride is a stunner in the chemical industry. It has many different names and is also well known in the industry. This substance is used in various fields of industry and has a wide range of uses. Or it is used in fine synthesis to help the birth of all kinds of wonderful things; or it is the key to the reaction, leading to changes in the invisible.
It is called by the world, and the aliases are intertwined with the trade names, such as the stars. "2,6-Difluorobenzenesulfonyl chloride", this is the correct name, but there are also other names, all of which refer to the same thing. In the chemical industry, it adds bricks and tiles to the progress of industry by virtue of its own unique characteristics. Although the names are similar and different, it is actually the same treasure, helping all kinds of craftsmen and drawing brilliant pictures of the chemical industry.
Safety & Operational Standards
Specifications for the safety and operation of 2,6-difluorobenzenesulfonyl chloride
The manufacturer of 2,6-difluorobenzenesulfonyl chloride is an important product in chemical research. Its characteristics are very special, and it is used for general chemical treatment. Therefore, it is known that its safe operation is very important.
In terms of safety, this product is corrosive, and it must be damaged due to the skin and mucous membranes. If it is accidentally damaged, it should be washed with a large amount of water as soon as possible, and it should be treated immediately. If it enters the eyes, it needs to be washed with water immediately, and it should not be rubbed, and it will be treated immediately. Its steaming is also irritating and harmful to inhalation, so it must be well handled in the place of operation to prevent steaming and polymerization.
The operation of the product is in accordance with the regulations. Those who need to take precautions, such as corrosion-resistant clothing, gloves, and eyes, etc., to ensure their own safety. When using it, it is appropriate to use appropriate equipment, and do not use it for storage. In the case of reverse operation, pay close attention to the reverse process, and control the pressure, force and other components according to the nature of the chemical reaction, to prevent accidents.
In addition, there is also a fixed storage method. It should be placed in the dry, dry and transparent environment, and the source of ignition, pollution and incompatible objects. Clear, clear product name, sex, harm, etc., so as to be effective.
Of course, in the research and use of 2,6-difluorobenzenesulfonyl chloride, the safe operation is such as the best, and the wings are indispensable. Only by following this principle can we avoid danger and prevent it from developing, so as to benefit the research and ensure the well-being of people.
Application Area
Today there is a product called 2,6-difluorobenzenesulfonyl chloride. This product has wonderful uses in many fields. In the field of medicine, it can be used as a key raw material to help synthesize special drugs and heal diseases. In the field of pesticides, it is also indispensable, which can contribute to the creation of high-efficiency and low-toxicity pesticides and protect the growth of crops. And in the field of material synthesis, it also shows its talents, so that the material properties can be optimized and improved. This 2,6-difluorobenzenesulfonyl chloride, due to its unique chemical properties, blooms brilliantly in various application fields, providing many possibilities for our scientific research and production. It is a treasure in the chemical industry.
Research & Development
Today there is a product called 2,6 - Difluorobenzenesulfonyl Chloride. As a chemical researcher, we have been studying it for many years.
The study of this product is related to many aspects. Its properties are unique and it plays a key role in chemical reactions. At the beginning, exploring its structure and characteristics was the cornerstone of the study. After repeated experiments, it was observed that it reacted with various things and explored laws.
In the process of research and development, we are committed to optimizing its preparation method. Strive to achieve this product with simpler steps and higher yield. Continuously improve the process, try new raw materials and conditions, and hope to break through limitations.
Looking at its development, the prospect is broad. In the fields of medicine, materials, etc., it is expected to show its talents. We should make unremitting efforts to promote its development, create new trends for various applications, and make this achievement benefit more fields.
Toxicity Research
Recently, I have studied the toxicity of 2,6 - Difluorobenzenesulfonyl Chloride. This compound is a commonly used raw material in the chemical industry, but its toxicity is unknown, which is related to the practitioners and the surrounding environment, so it is studied.
At the beginning, small animals were used as a test, and an appropriate amount of this agent was administered. Not long after, I saw the subject's body, the behavior was slightly different, or impatient or lazy, and the eating was also reduced. Looking at the anatomy, the organs changed slightly, and the color and quality of the liver and kidney were different from the past.
Tested with plants again, planted in the place where this agent was applied, its growth was slow, the leaves were gradually wilting, and the vitality was gradually lost.
In summary, 2, 6 - Difluorobenzenesulfonyl Chloride is toxic and harmful to animals and plants. Practitioners should take precautions to protect themselves and the environment.
Future Prospects
Fu 2,6-difluorobenzenesulfonyl chloride is emerging in today's chemical industry, and its future development is quite promising. With the advance of chemistry, new substances are coming out frequently. 2,6-difluorobenzenesulfonyl chloride has unique properties and is widely used in the production of medicine and pesticides.
In today's world, medicine is seeking new and more, and 2,6-difluorobenzenesulfonyl chloride can be a key material to assist in the research of new drugs. In the field of pesticides, it can increase the effect of drugs, and protect farmers and plants. With the advance of science and technology, the preparation method is getting better, the yield should be improved, and the quality should also be excellent.
And the day of environmental protection is hot, and the preparation and use of 2,6-difluorobenzenesulfonyl chloride must also follow the green path. In the future, or in more new areas, it will appear, adding to the prosperity of the industry and the progress of the world, and developing unlimited possibilities.
Where to Buy 2,6-Difluorobenzenesulfonyl Chloride in China?
As a trusted 2,6-Difluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,6-Difluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,6-difluorobenzenesulfonyl chloride?
2% 2C6-diethylnaphthyl phenol ether, its main uses are as follows:
This is a useful chemical compound. First, in the field of, or can be used as a synthetic compound. Due to the specific properties of, it can be used to synthesize compounds with specific biological activities. For example, it can be used to synthesize certain antibacterial and anti-inflammatory compounds. There are many synthetic steps, which can be skillfully modified, and can give new compounds the ability to treat specific diseases.
Second, it also has its own uses in the field of materials. Or it can be used as an addition to special polymer materials. Due to its special chemical properties, adding to polymer materials may improve the properties of materials. For example, to improve the quality of the material, so that it can better maintain the original physical and chemical characteristics under different environmental conditions; or to increase the resistance of the material, so that it is not easy to lose shape or performance degradation in high environmental conditions, and to expand the application of polymer materials, which can be used to create engineering plastics, plastics and other materials with higher requirements.
Third, in terms of chemical analysis, it can be filled with specific materials. Because it can reduce the biological properties of certain specific substances, it can generate materials with clear and specific characteristics. For example, it can be used to form compounds with specific colors or photoproperties, and to analyze the qualitative or quantitative analysis of these metals, which can help scientific researchers to analyze the environmental conditions, chemical analysis and other fields, and to determine the existence and content of specific substances.
What are the physical properties of 2,6-difluorobenzenesulfonyl chloride?
Barium 2% 2C6 -diethylaniline sulfonate is a chemical substance with the following physical properties:
From the perspective of this substance, it is often in the state of white powder, with uniform and delicate particles, pure color, no variegation and foreign matter, giving people a feeling of cleanliness.
Smell it, usually there is no obvious smell, placed in the air, and there is no irritating or special smell, which is quite stable.
In terms of solubility, it has low solubility in water and is difficult to dissolve with water at room temperature and pressure. However, in some organic solvents, such as ethanol, acetone, etc., it has a certain solubility and can be dispersed in it under suitable conditions to form a uniform system.
Its density is relatively large, and compared with common inorganic substances, it has a clear sense of weight. Under the same volume, the mass is heavier, which is one of its significant physical properties.
The melting point is quite high, and a higher temperature is required to cause it to melt. This property allows the substance to maintain a stable solid state under normal ambient temperature, and only under certain high temperature conditions will the physical state change and turn into a liquid state.
In addition, the powder of the substance has a certain fluidity. During storage and transportation, if the packaging is intact, it can flow smoothly and is not easy to agglomerate, which is conducive to subsequent processing and use.
Is the chemical properties of 2,6-difluorobenzenesulfonyl chloride stable?
The chemical properties of 2% 2C6-diethylnaphthalene cyanoether are relatively stable. Among this compound, the naphthalene group is a stable aromatic structure, and its conjugate system imparts considerable stability to the molecule, which is not easy to change due to ordinary chemical reactions. The diethyl group is attached to the naphthalene ring, which affects the electron cloud distribution of the naphthalene ring to a certain extent, but also enhances its steric hindrance effect, making it difficult for foreign reactants to approach the active check point, thereby further enhancing its stability.
Furthermore, the structure of the cyanoether part, the ether bond (C-O-C) is relatively stable, and it is not easy to break. Due to the high bond energy of carbon-oxygen bonds, high energy is required to break them. And the atomic arrangement and electron distribution in this structure make it resistant to common acid-base and redox conditions in the outside world.
Under normal conditions, if there are no extreme reaction conditions, such as high temperature, high pressure, strong oxidant or strong reducing agent, etc., 2% 2C6-diethylnaphthalene cyanoether can maintain its own chemical structure and properties. Even in common organic solvents or mild temperature environments, it can maintain a relatively stable state and rarely undergo chemical changes spontaneously.
However, it should be noted that although its chemical properties are stable, it can also exhibit certain reactivity under specific chemical reaction conditions. In case of reagents with special activities or severe reaction conditions, the substituents or ether bonds on the naphthalene ring may still undergo chemical reactions, such as substitution reactions, oxidation reactions, etc., depending on the specific reaction situation.
What is the preparation method of 2,6-difluorobenzenesulfonyl chloride?
To prepare 2,6-diethylaniline hydrochloride, the method is as follows:
First take an appropriate amount of aniline and place it in a clean reactor. The kettle must be made of glass or ceramic to prevent corrosion. Bathe in ice water and reduce the temperature in the kettle to 0 to 5 degrees Celsius. Slowly drop in sulfuric acid, stirring continuously when dripping, so that the two are fully mixed. The molar ratio of sulfuric acid to aniline should be 1.1 to 1.3:1. After dripping, keep this low temperature, stir for 1 to 2 hours, so that the sulfuration of aniline is complete.
Then, heat the reactor to 120 to 130 degrees Celsius, and introduce ethylene gas. The ethylene inlet rate must be moderate to make the reaction proceed smoothly. The molar ratio of ethylene to aniline is about 2.2 to 2.5:1. During the reaction, pay close attention to the pressure and temperature changes in the kettle to prevent accidents. When the reaction is completed, cool the material in the kettle to room temperature.
Pour the cooled material into a container containing an appropriate amount of water and stir well. Then, slowly add a solution of sodium hydroxide and adjust the pH to 8 to 9. At this time, 2,6-diethylaniline precipitates. Separate the organic phase with a liquid separation funnel, and then dry the organic phase with anhydrous sodium sulfate to remove water.
Finally, move the dried organic phase into another reactor and add an appropriate amount of hydrochloric acid. The concentration of hydrochloric acid should be 36% to 38%, and the volume ratio of the organic phase to hydrochloric acid should be about 1:1.2 to 1.5. Stir and heat up to 60 to 70 degrees Celsius, and react for 1 to 2 hours to obtain 2,6-diethylaniline hydrochloride. Excess hydrochloric acid and solvent are removed by vacuum distillation to obtain a pure product. During operation, strict procedures must be followed to pay attention to safety and prevent acid and alkali injuries and gas leakage.
What are the precautions for storing and transporting 2,6-difluorobenzenesulfonyl chloride?
2% 2C6-diethylnaphthalene blue dye is an important category of fine chemicals. During storage and transportation, many key matters should be paid attention to to to ensure its quality and safety.
When storing, the first environment is dry. This dye is easily affected by moisture. If the environment is humid, it may cause deliquescence and agglomeration, which will damage the performance. Therefore, it should be placed in a dry warehouse, and the humidity should be controlled at 40% - 60%. And the warehouse should be well ventilated to prevent the accumulation of harmful gases.
Temperature is also critical. The suitable storage temperature of this dye is 5 ° C - 35 ° C. If the temperature is too high, it may cause the dye to decompose and change color; if the temperature is too low, it may cause it to solidify and crystallize. Cooling facilities are required in hot summer, and warm means should be prepared in cold winter.
Furthermore, it is extremely important to avoid light. This dye is sensitive to light, and long-term light may cause it to fade and deteriorate. The storage place should be shaded from light, and dark containers or packaging are appropriate.
In terms of transportation, the packaging must be stable. Strong containers should be used to prevent package damage caused by collision and extrusion, and dye leakage. The loading and unloading process should be handled with care to avoid brutal operation.
The environment of the transportation vehicle also needs attention. It should be kept dry and clean, and should not be mixed with oxidizing agents, acids, alkalis and other chemicals, because it may react with these substances and endanger safety. And sun protection, rain protection and high temperature protection measures should be taken during transportation.
In addition, transportation and storage personnel need to be professionally trained to be familiar with the characteristics and precautions of the dye in order to deal with emergencies. In this way, 2% 2C6-diethylnaphthalene blue dye can be guaranteed to be safe and stable during storage and transportation.