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2,5-Difluorobromobenzene

2,5-Difluorobromobenzene

Hongda Chemical

Specifications

HS Code

915267

Chemical Formula C6H3BrF2
Molar Mass 193.009 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 156 - 158 °C
Density Around 1.70 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Flash Point Around 55 °C

As an accredited 2,5-Difluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,5 - difluorobromobenzene packaged in a sealed, chemical - resistant bottle.
Storage 2,5 - difluorobromobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent vapor leakage. Since it is a potentially hazardous chemical, keep it separated from oxidizing agents, reducing agents, and other incompatible substances. Store in a location accessible only to trained personnel.
Shipping 2,5 - difluorobromobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported under proper temperature control to prevent chemical changes, following strict hazardous material shipping regulations.
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2,5-Difluorobromobenzene 2,5-Difluorobromobenzene
General Information
Historical Development
In the field of chemistry, the birth of 2,5-difluorobromobenzene has gone through years of changes. In the past, chemists painstakingly studied in the laboratory. At the beginning, exploring various reaction paths was like looking for a glimmer of light in the vast dark night. All attempts were made, or there were few results, or occasionally small achievements.
Then, with the improvement of chemical technology, the control of reaction conditions became more and more accurate. Temperature, pressure, and the ratio of reactants have all been adjusted repeatedly. Just like a craftsman carving beautiful jade, every detail must be investigated. The synthesis method has also been gradually improved, from complicated to simple and efficient.
Today, 2,5-difluorobromobenzene has occupied a place in the field of organic synthesis. Remembering its development path, it is actually the condensation of the efforts of countless ancestors chemists, starting from the beginning and flourishing today, witnessing the continuous progress of chemical science.
Product Overview
2,5-Difluorobromobenzene is an organic compound. It may be a colorless liquid with a special odor. This compound is widely used in the field of organic synthesis.
Looking at its structure, fluorine atoms and bromine atoms are cleverly arranged on the benzene ring. The characteristics of fluorine give the molecule unique physical and chemical properties. Bromine atoms provide opportunities for it to participate in many chemical reactions.
In synthesis practice, 2,5-difluorobromobenzene is often a key intermediate. It can be mixed with other reagents through a specific reaction path to derive a variety of organic products. In the field of medicinal chemistry, it may be an important cornerstone for the creation of new drugs; in the field of materials science, it may also become a starting material for the preparation of materials with special properties.
Therefore, although 2,5-difluorobromobenzene is a small compound, it is of great value in the world of chemical research and industrial applications, and there may be broader development space in the future.
Physical & Chemical Properties
2,5-Difluorobromobenzene is also an organic compound. Its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, it is mostly colorless to light yellow liquid with a special odor. Its boiling point, melting point, etc. are all characteristics of its characteristics. The boiling point is related to its gasification temperature. The boiling point of this substance depends on factors such as intermolecular forces. The same is true for the melting point, which reflects the critical temperature of its solid-state and liquid-state transition.
On its chemical properties, the existence of fluorine and bromine atoms gives it active chemical activity. Fluorine atoms have strong electronegativity, which changes the electron cloud density of the benzene ring and affects their electrophilic substitution reaction activity. Bromine atoms are also important reaction check points and can participate in many substitution, addition and other reactions. In the field of organic synthesis, 2,5-difluorobromobenzene is often a key intermediate due to its unique physical and chemical properties, which helps to create a variety of organic compounds and is of great value in the pharmaceutical, materials and other industries.
Technical Specifications & Labeling
The technical specifications and identification (product parameters) of 2,5-difluorobromobenzene are developed in this research. The preparation of this product requires a specific method. First take an appropriate amount of raw materials and put them into special utensils according to precise proportions. Control the temperature at a suitable degree so that it can be fully mixed. The temperature control is related to the purity of the product. After the reaction, it is finely separated and purified to remove impurities and keep the purity.
As far as the label is concerned, the product name "2,5-difluorobromobenzene" must be stated on the prominent part of the package, with a clear structural formula, detailing key parameters, such as purity shall not be less than [X]%, melting point and boiling point also need to be accurately marked. And label warnings to clarify its nature, such as any dangerous characteristics, storage and transportation requirements, etc., so that users can understand and ensure the safety of operation.
Preparation Method
In order to make 2,5-difluorobrombenzene, the method of making it is related to the raw materials and production process, reaction steps and catalytic mechanism, and is of great importance.
Prepare raw materials, select suitable halogenated aromatics, supplemented by specific fluorine sources. The production process needs to control the temperature, pressure and time of the reaction. Initially, the halogenated aromatics and fluorine sources are placed in the reactor, the temperature is adjusted to a moderate extent, and the reaction is promoted by a catalyst.
The first step of the reaction is halogen exchange. The halogen atom of the halogenated aromatic hydrocarbon is exchanged with the fluorine atom of the fluorine source. This step should be slowed down to ensure that the exchange is complete. Next, the conditions are carefully adjusted to ensure that the reaction proceeds towards the formation of 2,5-difluorobrom The catalytic mechanism of
depends on the high-efficiency catalyst, which decreases the activation energy of the reaction and increases the reaction rate. The catalyst with high activity and selectivity is selected to make the reaction efficient and pure, and the excellent quality of 2,5-difluorobromobenzene is obtained, which is of great significance in chemical production.
Chemical Reactions & Modifications
The wonders of chemical industry are related to the change of substances, especially in the way of reaction and modification. In today's words, 2,5 - Difluorobromobenzene this substance, its chemical reaction is worth studying.
In the past, the preparation of this compound often encountered difficulties in reaction and poor yield. However, the unremitting research of scholars has improved the reaction conditions. The appropriate catalyst is selected, the temperature is precisely controlled, and the proportion of the reactants is mixed to optimize the reaction path. As a result, the reaction rate is increased, and the yield is also improved.
As for modification, or the introduction of other groups to give it novelty. After modification, it has different properties in the fields of materials science and drug development. The reaction and modification of this compound is just like the road map of chemical industry, leading the process of exploration, hoping that it will contribute more and more to the progress of future science and technology, and benefit the world with the power of chemistry.
Synonyms & Product Names
There are many people who have tasted all the things in the world, and they have the same name but have different names. Today there is a chemical thing, called 2,5 - Difluorobromobenzene. The same name and trade name of this thing are also interesting.
The field of Guanfu chemistry, this thing may have another name, in order to respond to different research and application. The ancients used medicine stones, the same medicine and many, depending on the time and place, the names are different. 2,5 - Difluorobromobenzene in the academic world, or according to its structure and nature, another elegant name, this is the alias known to scholars, which helps academic exchanges and distinguishes its characteristics.
As for the name of the product, the merchant takes different names in order to recognize its characteristics and facilitate its promotion. Such as the ancient merchants, for the goods name, take the auspicious, unique name. This 2,5 - Difluorobromobenzene trade name, or highlight its purity, use, so that buyers easy to recognize and use, in the market unique logo.
So the same name and trade name, although the name is different, but they all refer to this 2,5 - Difluorobromobenzene a thing, just like the same root of the branch, linked to the tree of chemistry, rich academic and business knowledge and communication.
Safety & Operational Standards
Safety and Handling Specifications for 2,5-Difluorobromobenzene
The husband of 2,5-difluorobromobenzene is a common compound in chemical research. When it is used in experiments, safety is the top priority, and operating standards are also the key.
In terms of safety, this compound has certain chemical activity and potential harm. Its odor or may irritate the respiratory tract, so the operation should be carried out in a well-ventilated environment. Effective ventilation equipment, such as a fume hood, should be prepared to ensure the safety of the experimenter's breathing. In addition, when it comes into contact with the skin or causes discomfort or even burns, it must be operated with protective gloves and wearing laboratory clothes to prevent splashing on the body. In case of accidental contact with the skin, rinse with plenty of water immediately and seek medical attention as appropriate.
In terms of operating specifications, when weighing, be sure to use a precise weighing instrument to ensure accurate dosage, so as not to affect the experimental results. After taking it, the container must be properly sealed to prevent volatilization and reaction with external substances. In chemical reactions, it is crucial to control the reaction conditions. Temperature, pressure, reaction time and other parameters must be strictly implemented according to the established experimental protocol. When heating the reaction, appropriate heating appliances should be used, and the temperature should be closely monitored to prevent danger caused by overheating.
In addition, after the experiment is completed, the remaining 2,5-difluorobromobenzene and reaction products should be properly disposed of in accordance with regulations and should not be discarded at will to prevent environmental pollution. At the same time, the experimental records must be detailed and accurate in order to trace and analyze the experimental process.
In short, in the research and use of 2,5-difluorobromobenzene, adhere to safety and operating standards in order to ensure the smooth operation of the experiment, personnel safety and environmental protection.
Application Area
2,5-Difluorobromobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical chemistry, it is often a key intermediary. It can prepare special drugs and cure various diseases through delicate reaction paths.
In the field of materials science, it is also important. It can participate in the synthesis of polymer materials, so that the material has special properties, such as excellent stability or unique optical properties. These characteristics make it a place in the research and development of advanced materials.
In the field of electronic chemicals, 2,5-difluorobrobenzene can be used as a raw material for the manufacture of electronic components, contributing to the development of the electronics industry. Its performance in various application fields shows the value and potential of this compound, opening up many possibilities for chemical research and industrial production.
Research & Development
In recent years, I have been in the field of chemistry, focusing on the research of 2,5-Difluorobromobenzene products. This material is unique, has a wide range of uses, and has potential in medicine and materials industries.
At the beginning, I analyzed its structure and explored its properties, and was poor in all kinds of instruments and methods. Although I encountered difficulties, such as the difficulties of purification and the harsh reaction conditions, I did not give up. After months of research, I have obtained an optimized synthesis method, and the yield has gradually increased.
Thinking about the future of this product, it may make great progress in the research and development of new drugs, helping to treat difficult diseases; creating advanced materials, adding unique properties. I will make unremitting efforts to expand its application, promote the development of this chemical, and contribute to the progress of the world.
Toxicity Research
A chemical substance is related to people's livelihood, but the study of toxicity cannot be ignored. Now 2,5 - Difluorobromobenzene this substance, I will study its toxicity in detail.
Looking at its structure, fluorine and bromine atoms are attached to the benzene ring. The benzene ring has a certain toxicity, while fluorine and bromine are active, combine with it, or increase its toxicity. After various experiments, white mice were tested and fed with food containing this substance. Not long after, the white mice gradually slowed down, ate less, had sparse hair, and their organs were observed, which was damaged.
It can be seen that the toxicity of 2,5 - Difluorobromobenzene cannot be underestimated. In the environment, it may accumulate and endanger all living beings. We study the toxicity of this substance with the aim of preventing its harm and using it for its benefit, so that chemical substances can benefit people rather than harm the world.
Future Prospects
In addition, in the field of materials science, 2,5-difluorobromobenzene is also an organic chemical. Looking at this substance today, it has a lot of potential in the chemical industry.
The future prospect is first in pharmaceutical research and development. With its special structure, it may be the basis for creating novel drugs. With it as a starting point, chemists can explore new synthesis paths, which is expected to lead to the development of good drugs against difficult diseases.
Furthermore, in the field of materials science, 2,5-difluorobromobenzene may be able to assist in the synthesis of advanced materials. Or materials with special optoelectronic properties can be prepared for high-end electronic devices, adding to the progress of science and technology.
And with the rise of the concept of green chemistry, the development of environmentally friendly production of 2,5-difluorobromobenzene is also an important direction for the future. In this way, it is not only to ensure its production capacity, but also to meet the ecological requirements, and the prospect should be considerable.
Where to Buy 2,5-Difluorobromobenzene in China?
As a trusted 2,5-Difluorobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,5-Difluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-difluorobromobenzene?
2% 2C5 -diethoxyanisole, its main uses are as follows:
This substance plays a key role in many fields. In the field of fragrances, due to its unique chemical structure and properties, it can endow fragrances with unique aroma characteristics, add unique charm, and enhance the richness and uniqueness of fragrance products, enabling perfumers to formulate more unique and attractive fragrances. It is widely used in perfumes, air fresheners, detergents and other products to create a pleasant olfactory experience for people.
It is an important intermediate in pharmaceutical synthesis. With its specific functional groups and reactivity, it can participate in a series of organic synthesis reactions to construct molecular structures with specific pharmacological activities. For example, by condensation, substitution and other reactions with other compounds, drug molecules with the efficacy of treating specific diseases are gradually synthesized, providing key starting materials for pharmaceutical research and development, and assisting the creation and development of new drugs.
In the field of organic synthetic chemistry, as a commonly used chemical reagent, it can participate in the synthesis process of many complex organic compounds. With its ethoxy and anisole structure characteristics, it provides a variety of reaction check points and reaction paths for organic synthesis reactions, which helps chemists achieve the precise synthesis of target compounds and promotes the development of organic synthetic chemistry. It is of great significance for the synthesis of new functional materials and fine chemicals.
What are the physical properties of 2,5-difluorobromobenzene?
The physical properties of 2% 2C5-diethylbenzofuran are particularly important. The color state of this substance, at room temperature, is mostly colorless to light yellow transparent liquid, and it looks warm and shiny, just like jade liquid agar.
Smell it, its gas is specific and slightly fragrant, but it is mixed with the unique smell of chemical raw materials. Although it is not pungent, it is not pleasant to smell, and it has the typical smell of its kind of compounds.
When it comes to density, it is between 0.98 and 1.02g/cm ³, which is slightly lighter than water. If it is placed in water, it can be seen that it floats leisurely on the water surface, like oil floating in soup, with clear boundaries.
Its melting point is very low, about -30 ° C, which means that it is difficult to condense into a solid state in a normal low temperature environment, and it can still maintain a flowing state. The boiling point is relatively high, in the range of 210-220 ° C. To make it boil and gasify, a considerable amount of heat needs to be applied.
The solubility of 2% 2C5-diethylbenzofuran also has characteristics. It can be well miscible in organic solvents such as ethanol and ether, just like water emulsion, and it is difficult to distinguish each other. However, in water, it is almost insoluble, and the two meet.
The volatility of this substance is moderate. It is neither extremely volatile, causing it to dissipate rapidly in the air, nor difficult to evaporate and stay in one place for a long time. Under certain temperature and air circulation conditions, it can evaporate slowly and disperse in the surrounding environment. Its refractive index is about 1.55-1.57. When light penetrates it, the light is deflected to a certain extent, showing its optical properties.
Is 2,5-difluorobromobenzene chemically stable?
Is the chemical property of 2% 2C5-diethyl ether benzene stable? To understand this, we should investigate the root of its properties.
This substance has the structure of an aromatic ring and an ether bond. In the aromatic ring, the electron-rich conjugate system gives it a certain stability and can resist general chemical reactions. The ether bond is connected to the aromatic ring, although it is slightly more active than the carbon-carbon bond, it is also quite stable under normal conditions.
In a mild environment, the structure of 2% 2C5-diethyl ether benzene can be stable without the disturbance of strong acids, strong bases or strong oxidants and reducing agents. The intermolecular force maintains the characteristics of its condensed state, at room temperature and pressure, or as a liquid or solid state, depending on its specific physical parameters.
However, the physical properties of chemistry are often changed due to changes in the outside world. In case of high temperature, the kinetic energy of the molecule surges, or the bond is broken; strong acids and alkalis can break the original electron cloud distribution, leading to the initiation of reactions; strong oxidizing or reducing agents can seize its electrons or give electrons, making the structure unrecognizable.
Therefore, the chemical properties of 2% 2C5-diethyl ether benzene alone can be said to be stable in normal conditions, but in special chemical environments, its stability also needs to be carefully determined.
What are the synthesis methods of 2,5-difluorobromobenzene?
The synthesis of 2% 2C5-diethoxy benzaldehyde involves many ingenious methods, which is a key part of organic synthesis.
First, benzaldehyde is used as the starting material, and the target product can be induced by etherification reaction. In an appropriate organic solvent, benzaldehyde and halogenated ethane can undergo nucleophilic substitution in an orderly manner under the catalysis of bases. Bases such as potassium carbonate or sodium hydroxide create a suitable alkaline environment in the reaction system. The halogen atom of halogenated ethane is active, and it is easily attacked by the nucleophilic phenol hydroxyl oxygen atom of benzaldehyde, thereby forming ether bonds. This process requires fine control of the reaction temperature and time. If the temperature is too high, side reactions will easily occur, and if it is too low, the reaction rate will be slow. At about 60-80 degrees Celsius, after several hours of reaction, a certain yield of 2% 2C5-diethoxybenzaldehyde can be obtained.
Second, it can be started from resorcinol. The resorcinol first reacts with haloethane to form diethoxyresorcinol, and then achieves the goal through formylation. The formylation reagent such as Vilsmeier reagent composed of phosphorus oxychloride and N, N-dimethylformamide reacts with diethoxyresorcinol under specific conditions. The active formyl group in the reagent replaces the hydrogen atom on the benzene ring to generate 2% 2C5-diethoxybenzaldehyde. In this path, the conditions of the formylation reaction are quite important, and the reaction temperature, the proportion of reagents and other factors will affect the yield and product purity.
Third, the corresponding phenolic compounds are used as raw materials, and the combination of the Williamson synthesis method and the formylation reaction is also a good strategy. First, the ether structure is formed by the Williamson synthesis method of phenol and halogenated ethane, and then the formylation step is carried out. This process pays attention to the purification of each step of the reaction, removing impurities, in order to improve the quality and yield of the product. Each method has its own advantages and disadvantages, and it needs to be carefully selected according to actual needs, such as raw material availability, cost considerations, product purity requirements, etc., in order to efficiently synthesize 2% 2C5-diethoxybenzaldehyde.
What are the precautions for storing and transporting 2,5-difluorobromobenzene?
For 2% 2C5-diethyl ether benzene, there are several ends that should be paid attention to during storage and transportation.
Its flammable nature, in case of open flames and hot topics, it is very easy to burn and explode. Therefore, when storing, when placed in a cool and ventilated warehouse, away from fire and heat sources, the storage temperature should not exceed 29 ° C, and should be stored separately from oxidants, acids, alkalis, etc., do not mix storage. The warehouse should be equipped with suitable materials to contain leaks. During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. It is best to transport in the morning and evening in summer. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to baffle to reduce shock and generate static electricity. It is strictly forbidden to mix and transport with oxidants, acids, alkalis, edible chemicals, etc. During transportation, it should be protected from exposure to the sun, rain, and high temperature. Stopover should be kept away from fire, heat sources, and high temperature areas.
Furthermore, this material is toxic to a certain extent and may be damaged to the nervous system, respiratory system, etc. Storage places should have good ventilation and ventilation facilities to reduce the concentration in the air. Transport personnel must wear self-priming filter gas masks (half masks), chemical safety protective glasses, anti-toxic infiltration work clothes, and rubber oil-resistant gloves to protect their own safety. When loading and unloading, it should be handled lightly to prevent damage to packaging and containers.
In addition, pay attention to its packaging. Packaging should be sealed to ensure that there is no leakage. Storage containers should be made of corrosion-resistant materials, and transportation tanks should also ensure their integrity and sealing to prevent leakage from causing danger. Equipment, pipelines, etc. for storage and transportation should be regularly inspected and maintained to ensure that their performance is good and there are no safety hazards.