Hongda Chemical
Products
Home  /  Products  / 

2,5-Difluorobenzenesulphonyl Chloride

2,5-Difluorobenzenesulphonyl Chloride

Hongda Chemical

Specifications

HS Code

376645

Chemical Formula C6H3ClF2O2S
Molecular Weight 226.60
Appearance Typically a colorless to pale yellow liquid
Boiling Point Approximately 118 - 120 °C at 10 mmHg
Solubility Soluble in common organic solvents like dichloromethane, chloroform
Reactivity Highly reactive towards nucleophiles, reacts with alcohols, amines
Hazard Corrosive, can cause burns to skin and eyes, harmful if inhaled or ingested
Storage Conditions Stored in a cool, dry place, away from moisture and incompatible substances

As an accredited 2,5-Difluorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,5 - difluorobenzenesulphonyl chloride packaged in a sealed glass bottle.
Storage 2,5 - difluorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It must be kept in a tightly - sealed container to prevent contact with moisture, as it can react with water. Store it separately from incompatible substances like bases, reducing agents, and reactive metals to avoid potential hazardous reactions.
Shipping 2,5 - difluorobenzenesulphonyl chloride is a hazardous chemical. Shipping requires proper packaging in accordance with regulations, like using corrosion - resistant containers. It must be clearly labeled and transported with care to avoid spills and ensure safety.
Free Quote

Competitive 2,5-Difluorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

2,5-Difluorobenzenesulphonyl Chloride 2,5-Difluorobenzenesulphonyl Chloride
General Information
Historical Development
2,5-Difluorobenzenesulfonyl chloride is also a chemical product. Tracing back to the past, its research and development process is like exploring a path. At the beginning, the chemical sages, in the laboratory, studied the properties of substances and explored the method of synthesis. After countless trials and errors, the technique of preparation was obtained. At that time, the conditions were simple and the equipment was simple, but the masters were determined and worked tirelessly. As the years passed, science and technology advanced, and the preparation process became more and more exquisite. From the crude at the beginning to the fine later, every step condensed wisdom. In the past, the output was scarce and only used for specific experiments. Nowadays, unlike in the past, the process has been improved, the output has increased greatly, and the use has also been widely used in various fields, which has contributed to the development of the chemical industry. This is also the trace of its historical evolution.
Product Overview
2,5-Difluorobenzenesulfonyl chloride is an important chemical in organic synthesis. Its color is colorless to light yellow liquid and has a pungent smell. In the field of organic synthesis, this product is widely used. It is often used as a sulfonylation reagent to react with alcohols, amines and other compounds to prepare key organic intermediates such as sulfonates and sulfonamides. This reaction condition is relatively mild and the yield is quite high, so it is very popular. Its chemical properties are active, and it is easy to hydrolyze in contact with water to generate corresponding sulfonic acids and hydrogen chloride. Therefore, it is necessary to strictly prevent moisture during storage. In the pharmaceutical, pesticide, material science and other industries, 2,5-difluorobenzenesulfonyl chloride plays an important role, providing key raw materials for the synthesis of many fine chemicals.
Physical & Chemical Properties
2,5-Difluorobenzenesulfonyl chloride is a special chemical substance. Its physical and chemical properties are particularly important and are related to applications in many fields.
Looking at its physical properties, it may have a specific color state at room temperature. Or it is a colorless to slightly yellow liquid, with a flowing texture and a clear appearance. Its boiling point, melting point and other data are crucial in studying its stability and application conditions. The boiling point or in a certain range, the melting point also has a corresponding value, which is its inherent characteristic.
As for chemical properties, 2,5-difluorobenzenesulfonyl chloride has active chemical activity. It can react with a variety of compounds. In case of nucleophiles, it is easy to initiate nucleophilic substitution reactions, and its sulfonyl chloride group is easily replaced by other groups. This property makes it useful in the field of organic synthesis and can provide a key step for the preparation of various complex organic compounds.
Technical Specifications & Labeling
The 2,5-difluorobenzenesulfonyl chloride is involved in the research of chemical products. Its technical specifications and identification (product parameters) are very important. The technical specifications of this product are related to purity, impurity limit, etc. To obtain high-purity 2,5-difluorobenzenesulfonyl chloride, it is necessary to carefully control the reaction conditions, such as temperature, duration, and ratio of reactants. In terms of identification, the name, chemical formula, molecular weight, and dangerous characteristics should be clearly stated. In this way, practitioners can know its properties and avoid risks when operating. Ensuring product quality and safety is the essence of chemical product research and production, and the same is true for the research and production of 2,5-difluorobenzenesulfonyl chloride.
Preparation Method
If you want to make 2,5 - Difluorobenzenesulphonyl Chloride, you must first clarify its raw materials and production process. The raw materials of this product should be taken from suitable fluoride and sulfur-containing compounds. The production process first needs to plan the reaction steps.
At the beginning, the fluoride and sulfur-containing compounds are mixed in an appropriate ratio, and the temperature is controlled in a moderate environment to make them respond slowly. In this reaction step, you need to observe the situation of the reaction, and adjust the temperature and speed according to its changes.
Next, set up an activation mechanism. The power of the catalyst can be used to accelerate and complete the reaction, and the purity and yield of the product can be improved. At the same time, between each step, the properties of the product are carefully checked, and subsequent operations are fine-tuned according to the results. In this way, only 2, 5 - Difluorobenzenesulphonyl Chloride of good quality can be obtained, and its preparation is essential, that is, the raw materials are finely selected, the reaction is orderly, the activation is obtained and the monitoring is meticulous.
Chemical Reactions & Modifications
Recently researched 2,5 - Difluorobenzenesulphonyl Chloride, I feel that its chemical application and modification are quite relevant. If you want to get the best effect, you must consider various factors in detail. For example, the temperature and the amount of agent are all related to the back and speed of the chemical application.
As for the modification, it is designed to make its properties more suitable for general use. Or increase its stability, or strengthen its activity, in order to expand its use. The two are related to each other. If the chemical application is good, the modification will be easy; if the modification is good, it will also promote the chemical application.
The research process, when carefully operated, detailed data recording, in order to analyze its changes, hope to be able to make progress in chemical treatment and modification, so that the properties of 2, 5 - Difluorobenzenesulphonyl Chloride are better, and provide the best thing for various uses.
Synonyms & Product Names
Today there is a thing called 2,5-difluorobenzenesulfonyl chloride. This thing is very important in my chemical research. It also has many synonymous names, either according to its nature or according to its structure, all of which express its characteristics.
This thing in the market has different trade names, but it all refers to the same thing. Among all chemical techniques, 2,5-difluorobenzenesulfonyl chloride participates in many reactions because of its uniqueness, and is an important part of the synthesis of various useful materials.
Our chemical researchers should study its properties in detail, understand its reaction rules, and hope to make good use of it to help the progress of chemistry, the creation of new materials, and the prosperity of industry and people's livelihood.
Safety & Operational Standards
On May 28, 2024, 2,5-difluorobenzenesulfonyl chloride is a chemical product that we have studied in depth. In the field of chemical industry, safety and operating standards have always been the top priority, which is related to the safety of practitioners and the stability and order of production.
2,5-difluorobenzenesulfonyl chloride has specific chemical properties, and its properties and reactivity need to be carefully controlled. For safety, when storing, choose a cool, dry and well-ventilated place to prevent water vapor and impurities from invading. It must be stored separately from alkalis, alcohols, etc., because it is easy to react violently with it and cause danger. When taking it, it is necessary to follow a precise process and wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent it from contacting the skin and respiratory tract.
The operating specifications should not be underestimated. During the reaction process, temperature, pressure and the proportion of reactants are all key factors. A slight error may cause the reaction to go out of control. During the synthesis process, the reaction conditions should be closely monitored and regulated to ensure the smooth progress of the reaction. And the experimental equipment needs to be regularly maintained and tested to ensure its stable performance and prevent safety hazards such as leakage.
In terms of waste treatment, the waste involved in 2,5-difluorobenzenesulfonyl chloride cannot be discarded at will and must be properly disposed of in accordance with environmental requirements. It can be converted into harmless substances by chemical methods, or handed over to professional institutions for treatment to reduce its harm to the environment.
As a chemical researcher, strictly abiding by safety and operating standards is a sign of responsibility to yourself, colleagues and the environment. Only in this way can the research and production of 2,5-difluorobenzenesulfonyl chloride be carried out safely and smoothly.
Application Area
2,5-Difluorobenzenesulfonyl chloride, which has a wide range of uses. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new special drugs or bring about a turning point for the treatment of difficult diseases. In the field of materials science, it can optimize material properties through special reactions, making materials have excellent performance in wear resistance, corrosion resistance, etc., and has broad application prospects in high-end equipment manufacturing materials. In the fine chemical industry, a series of high-value-added products can be derived, which can be used in the preparation of fine coatings and special additives to improve product quality and function. With its unique chemical structure, this compound plays a key role in multiple application fields and promotes technological innovation and progress in various industries.
Research & Development
Today there is a product named 2,5-difluorobenzenesulfonyl chloride. Our generation explored its research and development path as a chemical researcher. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, after analyzing its structure and distinguishing its characteristics, it was known that it could be used to create new agents, which could add a new way to the genus of medicine and pesticides. Then he focused his efforts to study the preparation method, and strived to improve its yield and quality.
After several years, the technology has gradually matured. The preparation method is good, but it is used for its own purposes. In pharmaceutical research and development, try to use it as a basis to make antibacterial agents, hoping to help people with pain. In the creation of pesticides, think about their properties, create drugs to kill harm, and help farming harvest.
Looking at its development, the prospect is broad. We should continue to study, so that this compound can shine in various fields and benefit the world.
Toxicity Research
Toxicity Study of 2,5-Difluorobenzenesulfonyl Chloride
The product of 2,5-difluorobenzenesulfonyl chloride is also a chemical product. As an explorer, we study its toxicity, which is related to human health and environmental safety.
The toxicity of this product cannot be ignored. At the beginning, when you take the product, you add 2,5-difluorobenzenesulfonyl chloride, which is the opposite of it. It may be irritable or depressed, and the physiological signs are very common. And analyzing its organs, liver, and other organs, it can be seen that this product can harm the normal operation.
And in the environment, there is also a shadow. If it is in the water, aquatic things are harmed by it, or less. If it is scattered in the air, people may inhale it, and the respiratory tract and skin will be invaded. In order to study its toxicity, prevent it, and control it, it is also our responsibility to ensure the safety of things and clear the environment.
Future Prospects
Wuguan 2,5 - Difluorobenzenesulphonyl Chloride is a unique product with a wide range of uses. Although the current knowledge is limited, the future prospects are shining brightly.
Today's field of chemistry is not only explored. This compound may emerge in the development of new drugs, and with its characteristics, it can accurately act on lesions and treat diseases for patients. Or in the material innovation, it can show extraordinary strength, improve material properties, and make it more suitable for the needs of the times.
Although the road ahead is long and the geometry is unknown, I firmly believe that with time and unremitting research, its potential will be tapped. At that time, Difluorobenzenesulphonyl Chloride will shine like a pearl, opening up a new world for the development of chemistry and the progress of mankind, bringing endless well-being and achieving future brilliance.
Where to Buy 2,5-Difluorobenzenesulphonyl Chloride in China?
As a trusted 2,5-Difluorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,5-Difluorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2,5-difluorobenzenesulfonyl chloride?
2% 2C5 -diethylbenzothiazole blue bromide, the physical properties of this substance are as follows:
Its color is blue-violet, and it looks quite distinct. Under normal conditions at room temperature, it is usually solid, with a solid texture and a certain crystalline form. The melting point is in a specific temperature range, which is the key node for its transformation from solid to liquid. Accurate determination is essential to grasp its physical properties.
In terms of solubility, it shows good solubility in some organic solvents, such as ethanol, acetone, etc., and can be fused with to form a uniform solution. This property makes it easy to prepare and use in many chemical experiments and industrial applications. However, the solubility in water is poor, and it is difficult to dissolve with water, showing obvious phase separation phenomenon.
Density is also one of its important physical properties. Compared with water, it has a specific density value, so that it can be used in operations such as liquid-liquid separation, and effective separation methods can be implemented according to density differences.
In addition, it has a certain stability. Under normal temperature, humidity and light conditions, it can maintain the relative stability of its own chemical structure and physical form. However, when exposed to high temperature, strong oxidants or extreme pH environments, the stability is easily destroyed, or the chemical structure is changed, which in turn causes the physical properties to change. The physical properties such as its appearance, melting point, solubility, density, and stability are of critical significance in many fields such as chemical engineering, materials science, and biomedicine, providing an important basis for its rational application.
What are the chemical properties of 2,5-difluorobenzenesulfonyl chloride?
2% 2C5 -diethylbenzaldehyde oxime chloride, this is an organic compound. Its chemical properties are unique and it has active reactivity.
From the structural point of view, the molecule contains a benzene ring, with ethyl groups attached to the 2 and 5 positions above the benzene ring, and has an aldehyde oxime structure and a chlorine atom. In the aldehyde oxime structure, the solitary pair electrons of the nitrogen atom give it a certain coordination ability, which can form complexes with metal ions, etc., and may have applications in the fields of catalysis and materials science. The chlorine atom is highly active and prone to substitution reactions.
It can be substituted with nucleophiles. For example, under alkaline conditions with alcohols, chlorine atoms can be replaced by alkoxy groups to form ether derivatives; when reacted with amines, nitrogen-containing new compounds can be formed, which may be an important step in drug synthesis. In addition, because of its aldehyde-oxime structure, it can participate in some specific condensation reactions, such as condensation with other compounds containing active hydrogen, to build more complex organic frameworks.
Due to its active chemical properties, caution is required when storing and using. It should be stored in a cool, dry and well-ventilated place to avoid contact with strong oxidants, strong bases and other substances to prevent violent reactions and endanger safety.
What are the main uses of 2,5-difluorobenzenesulfonyl chloride?
2% 2C5-diethoxybenzaldehyde, this substance has a wide range of uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. For example, when synthesizing some cardiovascular disease treatment drugs, it can go through a specific chemical reaction to build a drug activity structure and help the drug exert its efficacy.
In the fragrance industry, its role should not be underestimated. Because of its unique chemical structure, it can give fragrances a different aroma, add flavor layers and complexity, and is widely used to prepare high-end perfumes and fragrances to create a unique and charming fragrance.
In organic synthetic chemistry, as an important starting material, it can participate in a variety of organic reactions, such as condensation reactions with active hydrogen-containing compounds, building complex organic molecular structures, providing important support for the development of organic synthetic chemistry, and expanding the research on the types and properties of organic compounds.
In the field of materials science, it is converted into functional materials through specific chemical reactions, which are used to prepare materials with special optical and electrical properties, such as some optoelectronic materials, which play a unique role in optoelectronic devices and promote the development and innovation of materials science.
What is the preparation method of 2,5-difluorobenzenesulfonyl chloride?
The preparation method of 2% 2C5-diethylbenzaldehyde oxime ether is as follows:
First take an appropriate amount of 2,5-diethylbenzaldehyde and place it in a clean reaction vessel. This reactant needs to be carefully weighed to ensure that the reaction ratio is accurate. Then, an appropriate amount of oximing agent is added, usually an oximing agent such as hydroxylamine hydrochloride is more commonly used. When adding the oximing agent, it should be slow and uniform, and at the same time, gently stir to promote the full mixing of the two.
The control of the reaction temperature is very important. Generally speaking, it is appropriate to maintain the temperature of the reaction system in a moderate range, about 40 to 60 degrees Celsius. In this temperature range, the reaction can be carried out smoothly and efficiently, avoiding frequent side reactions due to high temperature or slow reaction rate due to low temperature.
During the reaction process, close attention should be paid to the reaction phenomenon. It can be observed whether the color of the solution changes, whether there is precipitation formation, etc. After the reaction lasts for a certain period of time, about 2 to 4 hours, use thin layer chromatography and other analytical methods to monitor whether the reaction is complete. If the reaction has not reached the expected level, the reaction time can be moderately extended.
After confirming that the reaction is complete, separate and purify the reaction product. First extract with an appropriate organic solvent to transfer the product to the organic phase. Commonly used organic solvents such as dichloromethane, ethyl acetate, etc., choose the appropriate one according to the characteristics of the product. After that, the organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove the moisture contained therein.
Finally, the pure 2,5-diethylbenzaldehyde oxime ether product can be obtained by removing the organic solvent by means of reduced pressure distillation. The whole preparation process requires strict adherence to the operating specifications and attention to the details of each link to obtain high-quality products.
What are the precautions for storing and transporting 2,5-difluorobenzenesulfonyl chloride?
2% 2C5 -diethylbenzaldehyde oxime ether is an important compound in fine chemicals. When storing and transporting, several items must be paid attention to.
One is related to the temperature and humidity of storage. The properties of this compound may be significantly affected by temperature and humidity. Under high temperature, it may cause chemical changes such as decomposition and polymerization, which will damage quality and efficiency. Therefore, when stored in a cool and ventilated place, the temperature should be controlled within a specific range, usually 5 ° C to 25 ° C. The humidity should not be too high. Excessive humidity may cause it to become damp and cause adverse reactions such as hydrolysis. The relative humidity should be maintained at 40% - 60%.
Second, the storage place must be kept away from fire and heat sources. 2% 2C5-diethylbenzaldehyde oxime ether is flammable, and it is dangerous to encounter open flames, hot topics or cause combustion or even explosion. In the warehouse, fireworks are strictly prohibited, and electrical equipment should also be explosion-proof to prevent electric sparks from igniting the object.
Third, when transporting, the packaging must be solid and reliable. Choose suitable packaging materials, such as strong plastic drums or iron drums, and seal well to prevent leakage. Transportation vehicles should also be equipped with corresponding fire equipment and leakage emergency treatment equipment for emergencies. During transportation, the driving should be stable to avoid violent vibration and collision to prevent package damage.
Fourth, the storage and transportation places should be equipped with clear warning signs. Clearly indicate the danger of this material, such as "flammable" and "harmful", so that the operator and surrounding personnel understand the latent risk and take appropriate protective measures.
Fifth, the operator must undergo professional training. Familiar with the characteristics, hazards and emergency treatment methods of 2% 2C5-diethylbenzaldehyde oxime ether. During storage and transportation operations, strictly follow the operating procedures and wear necessary protective equipment, such as protective gloves, protective glasses, gas masks, etc.