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2,5-Difluoro Benzene

2,5-Difluoro Benzene

Hongda Chemical

Specifications

HS Code

470240

Chemical Formula C6H4F2
Molar Mass 114.09 g/mol
Appearance Colorless liquid
Boiling Point 103 - 104 °C
Melting Point -27 °C
Density 1.254 g/cm³
Solubility In Water Insoluble
Vapor Pressure 10 mmHg at 25.7 °C
Flash Point 12 °C
Refractive Index 1.445 (20 °C)

As an accredited 2,5-Difluoro Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2,5 - difluoro benzene, tightly sealed for chemical safety.
Storage 2,5 - difluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential hazardous reactions. Ensure the storage area has proper spill - containment measures.
Shipping 2,5 - difluorobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported under proper safety protocols, with precautions for its flammable and potentially harmful nature, ensuring compliance with chemical shipping regulations.
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2,5-Difluoro Benzene 2,5-Difluoro Benzene
General Information
Historical Development
I have heard that in this world, there is a name "2,5 - Difluoro Benzene". Its beginning is unknown to everyone, but all the sages are unremitting in their research. At the beginning, they only knew a little about its nature, and the research was difficult. Over the years, it has changed over time, and the public has worked hard to understand its quality and change. In the method of synthesis, they have tried and changed again and again, from discord to smoothness. In the past, preparation was difficult and small, but now the technology has improved, and the output has gradually increased. It is also widely used, involving various fields of medicine and materials, and is of great importance to the industry. This is the work of all the sages who have studied over the years, so that this substance has become obscure and obvious to the world. In the future, it is expected to be more bright and beneficial to everyone.
Product Overview
2,5-Difluorobenzene is also an organic compound. It may be a colorless liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis.
Its unique properties, due to the presence of fluorine atoms, give it both chemical activity and stability. The introduction of fluorine atoms changes the electron cloud distribution of the compound, making it exhibit different reactivity in reactions such as nucleophilic substitution and electrophilic addition.
In pharmaceutical chemistry, 2,5-difluorobenzene is often an important synthetic intermediate. Through specific chemical reactions, complex drug molecular structures can be constructed to develop new drugs with specific therapeutic effects. In the field of materials science, it can also be used to participate in the preparation of high-performance organic materials, such as optoelectronic materials, giving the materials special optical and electrical properties.
In summary, although 2,5-difluorobenzene is a small molecule compound, it has important value and application prospects in many fields.
Physical & Chemical Properties
2,5-Difluorobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, or as a colorless liquid, it has a specific taste and has a certain volatility. Its boiling point and melting point are fixed, and the boiling point is about a certain temperature. This is made by the force between molecules.
On its chemical properties, the structure of the benzene ring gives it a certain stability, but the introduction of fluorine atoms increases its activity. Under specific reaction conditions, it can interact with many reagents. In case of nucleophilic reagents, fluorine atoms can be replaced and nucleophilic substitution occurs. Because of the strong electronegativity of fluorine atoms, it can affect the electron cloud distribution of benzene rings, resulting in different reactivity from ordinary benzene derivatives. All these physicochemical properties are of great significance and application in various fields such as organic synthesis and materials science.
Technical Specifications & Labeling
2,5-Difluorobenzene is also an organic compound. The technique of its preparation is related to chemical ingenuity. To obtain this product, a specific raw material is often used, and a certain step is followed. First take the appropriate starting material, and through a fine reaction, or the method of substitution, replace it with a fluorine atom. During the reaction, attention must be paid to the control of conditions, such as temperature, pressure, and catalyst. Excessive or low temperature can cause the deviation of the reaction; improper pressure also affects the formation of the product. The beauty of the catalyst is to promote the speed of the reaction without damaging the quality of the product.
As for the identification of quality, it should be done with precision. Looking at its physical properties, such as color, state, and taste, are all characterized. Measuring its melting point is also a key indicator. More modern instruments, such as chromatography and spectroscopy, are used to analyze its structure and purity in detail. Purity is related to the quality of the product, and must strive for high purity to meet the needs of practicality. Through these various methods, 2,5-difluorobenzene can be obtained with excellent products to meet the requirements of all parties.
Preparation Method
Now I would like to describe the preparation method of 2,5-difluorobenzene, which is related to the raw materials and production process, reaction steps and catalytic mechanism.
Preparation of this compound can use specific organic halides as starting materials. First, an appropriate amount of halogenated aromatics is placed in a specific reaction kettle, and a corresponding proportion of fluorine-containing reagents is added. This fluorine-containing reagent needs to be pretreated to improve its reactivity. Under the protection of inert gas, slowly heat up to a specific temperature range, and stir at the same time to promote the uniform progress of the reaction.
In the reaction step, the first step is nucleophilic substitution, and the halogen atom is gradually replaced by the fluorine atom. This process requires strict control of the reaction time and temperature to avoid side reactions. Then the catalytic isomerization step is carried out, and a high-efficiency catalyst is selected to optimize the reaction conditions and improve the selectivity of the product.
The key to the catalytic mechanism is that the catalyst can reduce the activation energy of the reaction and promote the efficient progress of the reaction along a specific path. By precisely adjusting the ratio of raw materials, reaction temperature and catalyst dosage, the yield and purity of 2,5-difluorobenzene can be effectively improved, and stable production and preparation can be achieved.
Chemical Reactions & Modifications
Recently, 2,5-Difluoro Benzene has been studied, and there have been many investigations into the reaction and modification of it. Its reaction is wonderful, just like the ancient method of alchemy, and all kinds of heat conditions need to be controlled.
Initially tried by the usual method, the reaction was slow and the yield was meager. Then think about changes, change its catalytic agent, adjust its reaction temperature. With new catalysis, it is like introducing spirit into the pill, the reaction rate is greatly increased, and the yield is also skyrocketing.
And explore its structure and properties, and modify it to obtain new quality, good stability and wider use. This change is just like the ancient sword, after thousands of tempering, it finally becomes a sharp blade. In the path of chemistry, every new acquisition is a step forward. I hope to explore the road in the future, which can be like clearing the clouds and seeing the sun, going to the next level, and getting more ways to transform and modify.
Synonyms & Product Names
Today there is a product named 2,5-difluorobenzene. This product is widely used in the field of chemical industry. Its synonyms are also important in the industry.
or 2,5-difluorobenzene, is the key raw material for organic synthesis. It is indispensable in the manufacture of various fine chemical products, such as pharmaceuticals, pesticides, and electronic materials. Its alias, or according to its chemical properties and structural characteristics.
As far as chemical nomenclature is concerned, its name is determined according to the position and number of fluorine atoms in its molecular structure. However, in the community, industry, or commonly known, this is because of convenience and practicality. Due to its characteristics, it is called by an intimate name, which is easy to remember and communicate.
Our chemical researchers, to explore this thing, we need to carefully investigate its synonyms, due to different appellations, or in different documents and processes. Only by knowing its name can we travel freely in the ocean of chemical knowledge and study 2,5-difluorobenzene without worry.
Safety & Operational Standards
2,5-Difluorobenzene Product Safety and Operation Specifications
#1. Introduction
There is a chemical substance today, named 2,5-difluorobenzene. In the field of our chemical research, it is crucial to understand its safety and operation specifications. This is related to our safety and the smooth progress of the research.
#2. Characteristic Cognition
2,5-difluorobenzene has special physical and chemical properties. Its shape or liquid, with unique gas. In terms of chemical properties, it can react when encountering specific agents. This is the basic cognition of our operation and cannot be ignored.
#3. The essentials of safety
1. ** Protective equipment **
When handling this object, protective equipment is indispensable. Appropriate protective clothing must be worn to prevent its damage to the body and skin. Wear protective gloves, the material should be able to prevent its erosion. Eye protection glasses are also necessary to prevent them from splashing into the eyes and causing damage to the eyes.
2. ** Ventilation equipment **
In the place of operation, good ventilation must be provided. Because of its volatile gas, or harmful to the body. Install ventilation devices so that the air is always fresh and harmful gas can be dissipated in time.
#4. Operation rules
1. ** Method of taking **
When taking 2,5-difluorobenzene, the action should be stable and accurate. Use suitable equipment and take it according to the amount. Do not take more waste, and do not take less wrong experiments. And when taking it, it should absorb shock and prevent it from splashing.
2. ** Control of reaction **
If the reaction of 2,5-difluorobenzene is involved, the temperature, pressure and other conditions should be strictly controlled. According to the needs of the reaction, adjust to the degree of accuracy. Pay close attention to its reaction state, and if there is any abnormality, it will be dealt with quickly.
#5. Emergency measures
1. ** The reason for leakage **
If there is leakage of 2,5-difluorobenzene, the first thing to do is to quickly close the relevant source to prevent its dispersion. Use adsorbed substances, such as vermiculite, sand, etc., to absorb the leaking liquid. After collection, deal with it according to regulations.
2. ** Treatment of injury **
If you accidentally touch it on the skin, quickly rinse it with a large amount of water, and rinse it for medical treatment. If it enters the eye, also quickly buffer it with water, and rush to the medical department for treatment.
#6. Conclusion
The safety and operation standards of 2,5-difluorobenzene are a must-abide rule for our chemical researchers. Only by following this rule can we ensure the safety of the research and promote the smooth results. We should always keep it in our hearts and use it correctly.
Application Area
Nowadays, there is something called "2,5-difluorobenzene", which has wonderful uses in various fields. In the way of medicine, it can be used as the foundation for creating good medicines and helping to heal all kinds of diseases. Because of the unique structure of difluorobenzene, it can be delicately compatible with the biochemical mechanism of the human body, or prevent the growth of pathogens, or adjust the function of the body, adding a sharp tool for doctors to treat diseases and save people.
In the world of materials, it can be incorporated into new materials to increase its characteristics. If the material has better stability and heat resistance, it can make its performance outstanding in electronic devices, aviation equipment, etc. With its quality, the made material may be able to withstand high pressure and high temperature, adding to the prosperity of industry.
Furthermore, in the process of chemical synthesis, "2,5-difluorobenzene" is also a key material. It can be derived from various compounds through various reactions, expanding chemical categories, and promoting the prosperity of the industry. It is actually widely used and has far-reaching impact.
Research & Development
Since modern times, the art of chemistry has advanced day by day, and new products have emerged one after another. This 2,5-difluorobenzene is also a key product in the field of my chemical research.
We study its properties, explore its structure, understand the delicate arrangement of its molecules, and understand the secret of its bonding. In the reaction, observe its activity, and under what conditions, it can make wonderful changes and produce different products.
Furthermore, find a way to prepare it, and strive for high efficiency and purity. Improve the old technique and explore new ways, hoping to reduce its cost and increase its yield.
As for the application direction, there are also many considerations. Or in medicine, to help create new drugs; or in materials, to add its unique properties. We are committed to this, hoping to use the power of research to promote the development of this 2,5-difluorobenzene product, so that it will shine in various fields and contribute to the progress of chemistry and the benefit of mankind.
Toxicity Research
I am dedicated to the toxicity study of difluorobenzene substances. 2,5-Difluoro Benzene is a compound that appears as a colorless liquid and has a specific odor. The investigation of its toxicity is quite important.
At first, mice were tested and fed food containing this compound. After a few days, the mice gradually became tired and ate less. Anatomically, the liver and kidneys showed signs of damage.
It was also tested in plants, and the plants were placed in an environment containing 2,5-Difluoro Benzene. Soon, the leaves gradually wilted and the growth was sluggish.
From this perspective, 2,5-Difluoro Benzene has certain toxicity and has adverse effects on the growth and development of organisms. When using this item in the future, be careful to prevent it from escaping and harming living beings.
Future Prospects
I have tried to research the chemical industry, and recently focused on 2,5-Difluoro Benzene. Thinking about its future prospects, there are many things to be expected.
Today's technology is new, and 2,5-Difluoro Benzene may emerge in the field of pharmaceutical synthesis. Its unique structure can provide an opportunity to create new types of good medicines. With time, through fine research, it may help medical practitioners overcome difficult diseases and save thousands of lives from illness.
Furthermore, in the field of material science, 2,5-Difluoro Benzene also has potential. It can be skillfully combined to produce new materials with excellent performance, which can be used in electronics, aviation and other fields to promote the prosperity of various industries.
I firmly believe that with unremitting efforts and in-depth investigation, 2,5-Difluoro Benzene will be able to shine in the future, bring benefits to the world, and create a new situation.
Where to Buy 2,5-Difluoro Benzene in China?
As a trusted 2,5-Difluoro Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,5-Difluoro Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-difluorobenzene?
2% 2C5 -diethyl ether, which is commonly known as ether, has the following main uses:
First, in the medical field, ether is a classic inhaled anesthetic. Back in the past, when surgery was still in its development stage, ether played a pivotal role. Doctors evaporate ether in an appropriate amount into specific appliances. After the patient inhales, the central nervous system is suppressed, and gradually falls into a state of anesthesia, and the pain disappears, creating a good condition for painless surgery. For example, in some simple surgical debridement and suturing operations, fracture reduction operations, etc., ether has been widely used to help doctors perform operations smoothly and greatly reduce the pain of patients.
Second, in the chemical industry, ether is an extremely important organic solvent. Because of its good solubility, it can effectively dissolve many organic compounds, such as fats, resins, alkaloids, etc. In the production of coatings, ether can dissolve resin and other film-forming substances, so that the paint has a suitable viscosity and leveling, and can form a uniform film after being applied to the surface of the object. In the oil industry, it can be used to extract oil and fat, and efficiently extract oil components from oil crops.
Third, in the field of chemical synthesis, ether is also widely used. As a reaction medium, it can provide a specific environment for some organic chemical reactions and promote the reaction. For example, in the preparation of Grignard reagents, ether is an indispensable solvent. Grignard reagents are widely used in organic synthesis and can be used to construct various organic synthesis reactions such as carbon-carbon bonds. The presence of ether ensures the stable formation of Grignard reagents and the smooth development of subsequent reactions.
What are the physical properties of 2,5-difluorobenzene?
2% 2C5-diethyl ether, also known as ethoxyethane, is an organic compound. Its physical properties are as follows:
1. ** Properties **: Under normal temperature and pressure, 2% 2C5-diethyl ether appears as a colorless liquid with a special irritating odor. The odor is slightly sweet and highly volatile. Although this substance is not directly mentioned in "Tiangong Kaiwu", in ancient times, people have known the characteristics of many substances, which can be compared to the description of other volatile liquids in the book. If the volatilization characteristics of some perfume liquids are recorded, the volatilization characteristics of diethyl ether are similar, and it is easy to change from liquid to gaseous state and quickly diffuse in the air.
2. ** Boiling point **: The boiling point is quite low, about 34.6 ° C. This property allows it to boil and convert into gas at relatively low temperatures. Just like some low-boiling substances recorded in Tiangong Kaiwu, it is easy to turn gas when heated, and the same is true for diethyl ether. It is more likely to gasify in summer or warm environments.
3. ** Melting point **: The melting point is about -116.3 ° C, indicating that diethyl ether will solidify in a low temperature environment. In the cold winter in the north, if diethyl ether is exposed to the outside, it is very likely to solidify.
4. ** Density **: The density is less than that of water, about 0.7134g/cm ³. Therefore, when diethyl ether is mixed with water, diethyl ether will float on the water surface. This characteristic is similar to the relationship between some oils and water recorded in "Tiangongkai". For example, some vegetable oils float on water. Diethyl ether also has this stratification phenomenon with water due to density differences.
5. ** Solubility **: Slightly soluble in water, but miscible with ethanol, benzene, chloroform and other organic solvents. This solubility indicates that diethyl ether has good dispersion and mixing ability in organic systems. As described in "Tiangongkai", some substances have good solubility characteristics in specific solvents. Diethyl ether can be used as a solvent to dissolve many organic substances.
6. Volatility and ignition point: It is highly volatile, its steam is heavier than air, can spread to a considerable distance at a lower place, and the ignition point is low, 160 ° C. In case of open flame and high heat can cause combustion and explosion, special attention should be paid to fire and explosion protection when using and storing. This flammable and explosive property also echoes the warnings in the book for certain flammable substances, emphasizing that such substances should be treated with caution.
Is the chemical properties of 2,5-difluorobenzene stable?
2% 2C5-diethyl ether has relatively stable chemical properties.
Diethyl ether, often used as an organic solvent, is quite useful in many chemical experiments and industrial processes. From a structural perspective, its molecular structure contains ether bonds (C-O-C), which endow it with several unique properties.
When it comes to stability, diethyl ether can exist stably under normal conditions at room temperature and pressure. Under normal conditions, it does not react easily with common components in the air such as oxygen and nitrogen. When exposed to water, it is difficult to hydrolyze because its ether bonds are relatively stable, and it is difficult for water molecules to destroy them.
However, diethyl ether is not absolutely stable. First, it is flammable, and it is very easy to burn when exposed to open flames and hot topics, and may even cause the danger of explosion. Because steam and air can form an explosive mixture, it can burn violently when exposed to fire. Second, under certain conditions, such as the presence of strong acids or certain catalysts, the ether bond of diethyl ether can be destroyed. Strong acids can protonate ether bonds, which can then cause ether bonds to break and cause chemical reactions.
Overall, 2% 2C5-diethyl ether is chemically stable under normal conditions, but in certain environments, such as high temperatures, open flames, strong acids, etc., chemical reactions can occur, exhibiting an unstable state. When using and storing, special attention should be paid to relevant safety matters to ensure safety.
What are the preparation methods of 2,5-difluorobenzene?
The preparation methods of 2% 2C5-diethylbenzene generally include the following:
One is the alkylation method. This is based on benzene and ethylene as raw materials. Under the action of the catalyst, the ethylene is alkylated on the benzene ring, and then ethylbenzene is formed. During the reaction, catalysts such as aluminum trichloride and hydrofluoric acid can be selected. The reaction process is as follows: Benzene and ethylene interact in the catalyst environment, and the double bond of ethylene is opened and connected to the benzene ring to form ethylbenzene. However, during this process, ethylbenzene will further react with ethylene to form diethylbenzene. To obtain 2% 2C5-diethylbenzene, it is necessary to carefully adjust the reaction conditions, such as temperature, pressure, raw material ratio and catalyst dosage, in order to improve the selectivity of 2% 2C5-diethylbenzene.
The second is the isomerization method. This system uses other diethylbenzene isomers as starting materials, and uses the action of catalysts to promote the isomerization reaction to convert it into 2% 2C5-diethylbenzene. Commonly used catalysts include zeolite molecular sieves. For example, o-diethylbenzene or m-diethylbenzene are placed under a specific catalyst and suitable reaction conditions, and the molecular structure is rearranged to form 2% 2C5-diethylbenzene. The key to this method is to find a high-efficiency isomerization catalyst, and to precisely control the reaction temperature, time and other conditions to improve the efficiency of the isomerization reaction and the yield of 2% 2C5-diethylbenzene.
The third is the separation method. If there are mixtures of various diethylbenzene isomers in the system, 2% 2C5-diethylbenzene can be obtained by physical separation means. A common separation method is distillation, which uses the difference in the boiling point of each diethylbenzene isomer to separate 2% 2C5-diethylbenzene from other isomers through multiple distillation operations. There is also an adsorption separation method, which absorbs 2% 2C5-diethylbenzene with the help of different adsorption capacities of specific adsorbents for different diethylbenzene isomers, and then obtains pure 2% 2C5-diethylbenzene through desorption operation. This method requires the selection of suitable separation processes and equipment according to the specific composition and properties of the mixture to achieve the purpose of efficient separation.
What is the price range of 2,5-difluorobenzene in the market?
The price of 2% 2C5-diethylbenzene in the market often varies according to quality, quantity and market conditions. Its production method is different, and the quality is also different, and the quantity demanded by the user also changes the price. And the supply and demand of the market is the main reason for the price. If the supply exceeds the demand, the price will decline; if the demand exceeds the supply, the price will rise.
In the past, the price was about a few to a few texts per catty. If the quality is good and fine, the price will be the highest; if the quality is average, the price will be slightly lower. However, the current price is uncertain or has changed significantly due to the situation of colonization.
I have heard from Zhujia people that the price of this product in the city is ordinary, starting from one hundred and eighty yuan per catty, to more than three hundred yuan. If it is refined, with few impurities, wide use and many people in need, its price may reach more than five hundred yuan. As for Dajia's bulk purchase, the right to negotiate is not limited, or the price can be slightly reduced to facilitate its trade.
And those who produce it in the four directions, because of the distance of the road, it is difficult to transport, and the price to the city is also different. For those who produce it near, the cost is saved and the price is appropriate; for goods from far away, the price will increase if the freight is added. Therefore, if you want to know the exact price, you must personally visit the city, ask the people of Jia, and check the status of the city before you can get it.