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2,5-Dichlorofluorobenzene

2,5-Dichlorofluorobenzene

Hongda Chemical

Specifications

HS Code

794230

Chemical Formula C6H3Cl2F
Molar Mass 165.00 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 174 - 176 °C
Melting Point -27 °C
Density 1.435 g/cm³ at 20 °C
Vapor Pressure 1.33 hPa at 34.6 °C
Flash Point 63 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether

As an accredited 2,5-Dichlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,5 - dichlorofluorobenzene packaged in a sealed, corrosion - resistant bottle.
Storage 2,5 - Dichlorofluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be kept in a tightly closed container made of materials compatible with the chemical, such as steel or certain plastics. Avoid storing it near oxidizing agents. Label the storage container clearly to prevent misidentification.
Shipping 2,5 - dichlorofluorobenzene is shipped in sealed, corrosion - resistant containers. These are carefully packaged to prevent leakage. Shipments follow strict chemical transport regulations, ensuring safe transit to the destination.
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2,5-Dichlorofluorobenzene 2,5-Dichlorofluorobenzene
General Information
Historical Development
Taste the chemical industry, development and changes, there is a thing called 2,5-dichlorofluorobenzene, and its traces can be found in the past. At the beginning, science was not yet developed, and this compound was little known. Later scholars have deepened their research and advanced their technology.
In the past, the art of organic synthesis was still simple, and the preparation of 2,5-dichlorofluorobenzene was explored with great difficulty. However, the ancestors made unremitting efforts and made countless attempts to find a way. From the initial simple method, the yield was meager, to the later process improvement, the yield was gradually enriched.
Looking at its application, it was initially limited to niche scientific research. With the passage of time, it has emerged in the fields of medicine and pesticides, and the demand is increasing day by day. Therefore, the historical development of 2,5-dichlorofluorobenzene is a testament to the evolution of science and technology and human exploration.
Product Overview
"Overview of 2,5-Dichlorofluorobenzene Products"
Fu 2,5-dichlorofluorobenzene is a crucial raw material in organic synthesis. Its properties are colorless to light yellow liquid, with a special odor, insoluble in water, and miscible in most organic solvents.
The preparation of this product is often obtained by a specific halogenation reaction. In the reaction process, the temperature, the proportion of reactants and other conditions must be strictly controlled to obtain high-purity products.
In the industrial application field, 2,5-dichlorofluorobenzene is widely used. It is often a key intermediate in the synthesis of medicines and pesticides. In the creation of medicine, it can help develop new antibacterial and antiviral drugs; in the development of pesticides, it can be used to synthesize highly efficient and low-toxicity insecticides, herbicides, etc.
Because of its significant position in the field of organic synthesis, ensuring its quality and stable supply is of great significance to the development of related industries.
Physical & Chemical Properties
2,5-Dichlorofluorobenzene is an organic compound. Its substance has specific rationalization. Looking at its shape, it is a colorless liquid at room temperature and has a special odor. Its boiling point is about [X] ° C, the melting point is at [X] ° C, and it can maintain a stable state in a specific temperature range.
When it comes to solubility, it is slightly soluble in water, but it is easily soluble in organic solvents such as ethanol and ether. This is due to the characteristics of halogen atoms and fluorine atoms in its molecular structure, which makes it interact weakly with water, and can interact with organic solvents by van der Waals force.
Its chemical activity is quite high, and it is prone to nucleophilic substitution reactions due to the existence of halogen atoms. Under suitable conditions, it can be attacked by nucleophiles, causing halogen atoms to be replaced, and a variety of organic compounds can be derived. It has a wide range of uses in the field of organic synthesis.
Technical Specifications & Labeling
Nowadays, there is a substance called 2,5-dichlorofluorobenzene, which has attracted much attention in chemical research. Its process specifications and standards (product parameters) are the key. The preparation of this product requires a precise process. The selection of raw materials, when high purity is the best, the ratio must be accurate. When reacting, temperature, pressure and other conditions need to be strictly controlled. If the temperature is too high, it may increase side reactions; if the pressure is not appropriate, it will affect the purity of the product.
The method of testing also has rules. Looking at its color, it should be pure and translucent; measuring its purity, when it reaches a specific standard. The impurity content must be extremely low. In this way, high-quality 2,5-dichlorofluorobenzene products can be obtained to meet the needs of all parties and develop their functions in the chemical field.
Preparation Method
In order to make 2,5-dichlorofluorobenzene, the method of making it is related to the raw material and production process, reaction steps and catalytic mechanism, which is really the key.
First of all, when selecting suitable starting materials, such as chlorine-containing and fluorine-containing aromatics, this is the basis for the reaction. In the production process, the temperature, pressure and duration of the reaction need to be controlled. In a specific reactor, the raw materials are reacted. The reaction step, or pre-halogenation, introduces chlorine atoms, and then fluoridates to obtain the target product. During halogenation, choose the appropriate halogenating agent, control the reaction conditions, and precisely replace the chlorine atoms. When fluorinating, also choose the appropriate fluorinating reagent to find the best reaction parameters.
As for the catalytic mechanism, choosing a high-efficiency catalyst can increase the reaction rate and reduce the energy barrier of the reaction. The catalyst may interact with the raw material, change the reaction route, and promote the formation and transformation of intermediate products, eventually forming 2,5-dichlorofluorobenzene. All of these are the necessary methods for preparing this substance, and require careful consideration and careful operation.
Chemical Reactions & Modifications
I have tried to study 2,5 - Dichlorofluorobenzene this substance, and I have a lot of thought in the chemical reaction and modification. The way of the reaction, at first, followed the usual method, with all the reagents in common, but the results obtained did not meet my expectations.
After studying the structure of its molecules in detail, thinking about the difference in its bond energy, then changing the method. With the control of temperature and pressure, coupled with special catalysis, a new reaction path was obtained. This change also greatly increased the rate of the reaction, and the purity of the product was better than before.
As for the modification, I tried to add different groups to its molecules. At first, the effect was not obvious, but after many adjustments, it was effective. After modification, its physicochemical properties are greatly changed, and it may have wider applications in various fields. This is the result of my research, and I hope it can be used as a lesson for those who are good at it.
Synonyms & Product Names
As stated in "Mengxi Written Talks", it is often said that one thing is more than one wonder. Today, there is 2,5-dichlorofluorobenzene, which is also known as a synonymous name and a commodity.
2,5-dichlorofluorobenzene, its synonymous name, is commonly used in the field of chemistry, accurately describing its molecular structure, so that the communication of scholars is correct. And the name of the commodity is mostly for the needs of the market, which is convenient for industry operators and users to call it.
In the course of my chemical research, I am well aware of the importance of this name being different but identical. The name of synonymy helps us to analyze its nature and reason, and explore its mysteries with scientific methods. The name of the product is in the market circulation, so that the supply and demand are clear and the transaction is convenient. The two complement each other, promoting 2,5-dichlorofluorobenzene for industrial and scientific research, and it is also a key guide for our generation of chemical research and application.
Safety & Operational Standards
Specifications for the safety and operation of 2,5-dichlorofluorobenzene
Fu 2,5-dichlorofluorobenzene is an important substance in chemical research. Safety and operating practices must be observed in all aspects of its preparation, use and storage to avoid accidents, ensure the safety of personnel and the environment.
When preparing, all instruments must be clean and dry. The weight of raw materials should be accurate to meet the needs of the reaction. The reaction device must be stable and well sealed to prevent the escape of gas. During the reaction process, the control of temperature and pressure is the key. Appropriate cooling or heating devices should be set up to ensure the smooth progress of the reaction without overheating or runaway.
When using, the experimenter must wear protective equipment, such as gloves, goggles, protective clothing, etc., to avoid direct contact with the substance. The operation is suitable in a well-ventilated place, and it is best to have a fume hood, which can drain the volatile gas in time and reduce its concentration in the air. When using the substance, use suitable equipment, be careful to avoid spillage.
For storage, 2,5-dichlorofluorobenzene should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources to prevent it from decomposing or causing fire. Storage containers must be tightly sealed and clearly marked, indicating the name, nature and precautions of their contents. Regularly check the condition of the storage environment and containers. If there is any abnormality such as leakage, take immediate measures to dispose of it.
When disposing of waste, do not discard it at will. Waste containing 2,5-dichlorobenzene should be collected by classification in accordance with relevant regulations and standards, and delivered to a qualified treatment agency to properly handle it in a professional way to avoid pollution to the environment.
In short, in the entire process of 2,5-dichlorobenzene, safety and operating standards follow closely. Experimenters should keep it in mind and practice it at all times to ensure that everything goes smoothly and is worry-free.
Application Area
2,5-Dichlorofluorobenzene has a unique use in various chemical products. Its application field is quite broad. In the field of medicine, it is often a key raw material to help doctors make special drugs, treat various diseases, and save people from diseases and pains. In the field of agrochemistry, it is also an important material. Agricultural agents are used to protect fields and crops, protect them from insect damage and disease disturbance, and hope for a bumper harvest. In the synthesis of materials, it is also indispensable. It can be used as a material with special properties and is used in various high-tech places, such as electronic devices, to make its performance better and efficiency better. Therefore, 2,5-dichlorofluorobenzene plays a pivotal role in various application fields, and is an important angle for promoting the progress of various industries.
Research & Development
I have been studying the chemical industry for many years, and now I focus on the research and development of 2,5-dichlorofluorobenzene. This compound has unique properties and many potential applications.
At the beginning, I explored its synthesis method. After repeated experiments, I tried different paths. Either halogenation or substitution, strive to optimize the process and improve the yield and purity.
In the application field, it is found that it can be used as a key intermediate in pharmaceutical synthesis, laying the foundation for the creation of new pharmaceuticals. Also emerging in materials science, it is expected to become a raw material for high-performance materials.
However, the road of development is full of challenges. The control of synthesis cost and the harsh reaction conditions all need to be overcome. Our generation should adhere to the spirit of research and make unremitting efforts to expand its application, promote the development of this product, and contribute to the chemical industry, causing it to bloom.
Toxicity Research
Since modern times, the rise of chemistry has also led to the emergence of various compounds. Now, the toxicity of 2,5-dichlorofluorobenzene is related to people's livelihood and health, and it is also of great importance to our chemical researchers.
Test 2,5-dichlorofluorobenzene, is it strong in nature? Where is the source of toxicity? First observe the structure of its molecules, chlorine and fluorine atoms are attached to the benzene ring, or cause toxic changes. After various experiments, involve the body of animals, observe its physiological characteristics. If it enters the genus of rodents, or causes organ violations, it will disturb the liver and kidney.
And its volatile gas enters the air. If a person inhales it, it can cause discomfort to the mouth and nose, which may be serious or damage the respiratory system, and the central nervous system is also affected by it. However, in order to clarify its toxicity, it is necessary to collect extensive data and refer to the results of the experiment to accurately judge it, provide evidence for protection and use, and prevent it from being poisonous to the world.
Future Prospects
2,5-Dichlorofluorobenzene is also a chemical substance. There is no way to do it now. Its way of synthesis may be the cornerstone of new research, helping those who overcome common diseases and save people. In the field of materials, it is also expected to develop new ways to create materials with outstanding performance to meet the needs of all walks of life.
Our researchers, we should make sense of it and explore it. The heart of intensive research and the heart of ambition, we hope to dig more of its power. Make this 2,5-dichlorofluorobenzene, before it is widely used, used in the world, benefit the people, and become the grand goal of our researchers.
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As a trusted 2,5-Dichlorofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,5-Dichlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-dichlorofluorobenzene?
2% 2C5-difluoroethylbenzene is also an organic compound. It has a wide range of uses and has applications in various fields.
In the field of medicinal chemistry, this compound is often an important synthetic intermediate. Physicians want to make some specific drugs, often rely on 2% 2C5-difluoroethylbenzene as the starting material, and through multiple delicate chemical reactions, the specific structure of the drug molecule is constructed. Due to its unique chemical properties, it can precisely introduce specific functional groups to help the drug obtain the required biological activity and pharmacological properties to cure various diseases.
In the field of materials science, 2% 2C5-difluoroethylbenzene also has a role that cannot be ignored. When making some high-performance polymer materials, it is integrated into the material system as a monomer or additive. In this way, the properties of the material can be significantly improved, such as improving the thermal stability, mechanical properties and chemical stability of the material. The products made of this material can be applied to more severe environments, such as aerospace, electronics and other fields that require extremely high material properties.
In the field of organic synthetic chemistry, 2% 2C5-difluoroethylbenzene is a key building block for the synthesis of complex organic molecules. Chemists use its selective reactions with other compounds to ingeniously build a diverse organic framework, opening up a broad path for the creation of new organic materials and functional molecules, and promoting the continuous progress and development of organic synthetic chemistry.
In summary, 2% 2C5-difluoroethylbenzene plays a pivotal role in many fields such as medicine, materials, and organic synthesis, and has made significant contributions to technological progress and innovation in various fields.
What are the physical properties of 2,5-dichlorofluorobenzene?
2% 2C5-difluoroethylbenzene is also an organic compound. Its physical properties are quite important and are detailed as follows:
- ** Physical state and color **: Under normal temperature and pressure, 2% 2C5-difluoroethylbenzene is mostly a colorless and transparent liquid with a pure appearance and no visible impurities. This pure state ensures the stability and uniformity of its participation in reactions in many chemical applications.
- ** Odor **: It has a special aromatic smell, but this smell is not pungent and intolerable, but a milder aromatic smell. This unique smell may have unique uses in some specific fragrance blending or fine chemical fields.
- ** Melting point and boiling point **: The melting point is about -40 ° C, and the boiling point is between 150-160 ° C. The lower melting point allows it to maintain a liquid state in a relatively low temperature environment, which is convenient for the transportation and mixing of materials; while the moderate boiling point is easy to separate from other substances during distillation, distillation and other separation operations to achieve its purification and purification.
- ** Density **: The density is about 0.98 - 1.02g/cm ³, which is slightly heavier than the density of water at 1g/cm ³. This density characteristic has a significant impact on the chemical process involving liquid-liquid separation or phase equilibrium, and is related to the efficiency and effect of operations such as stratification and extraction.
- ** Solubility **: Slightly soluble in water, but can be miscible with most organic solvents, such as ethanol, ether, acetone, etc., in any ratio. This solubility characteristic provides a wide range of options for the construction of organic synthesis reaction systems. According to the reaction requirements, suitable solvents can be selected to optimize the reaction conditions.
- ** Volatility **: It has a certain degree of volatility and will gradually evaporate into the air in an open environment. This characteristic needs to be taken seriously during storage and use, and it should be properly sealed and stored to avoid material loss. At the same time, attention should be paid to the safety and environmental problems that may be caused by its volatilization in the air.
Is the chemical properties of 2,5-dichlorofluorobenzene stable?
The stability of the chemical properties of 2% 2C5-difluoroethylbenzene depends on various factors. In this substance, the introduction of fluorine atoms significantly changes its properties. Fluorine has high electronegativity, can cause molecular polarity to increase, and the carbon-fluorine bond energy is quite large.
From the perspective of reactivity, due to its structure, in the nucleophilic substitution reaction, the reactivity may be different from that of ordinary ethylbenzene. The carbon-fluorine bond is relatively stable, and high energy is required to make the fluorine atom leave. Therefore, under normal conditions, its tendency to participate in the nucleophilic substitution reaction is weak, which may show its certain stability.
However, under certain conditions, such as high temperature and the presence of a strong catalyst, it can also participate in the reaction. In case of strong oxidizing agent, or due to the presence of benzene ring and side chain, oxidation reaction occurs. Although the carbon-fluorine bond is stable, the benzene ring can be oxidized, and the side chain may also be oxidized and modified, which shows that its stability is not absolute.
In terms of thermal stability, the high bond of the carbon-fluorine bond can make the molecular skeleton stable within a certain temperature. However, if the temperature exceeds a certain threshold, the molecular structure may change, such as bond breaking and rearrangement.
In summary, 2% 2C5-difluoroethylbenzene has certain chemical stability, but it is not absolutely stable. It may exhibit different reactivity and stability under different environmental conditions, depending on the specific reaction conditions and the chemical reagents encountered.
What are the production methods of 2,5-dichlorofluorobenzene?
There are several ways to prepare 2% 2C5-difluorobenzyl alcohol.
First, 2,5-difluorotoluene is used as the starting material, and it is halogenated through the side chain. In the presence of light or initiator, it reacts with halogens (such as chlorine gas and bromine) to obtain 2,5-difluorobenzyl. Then the halobenzyl is reacted with nucleophilic reagents such as water or alkoxides, and the halogen atom is replaced by a hydroxyl group to obtain 2,5-difluorobenzyl alcohol. This step is relatively clear, but the halogenation step needs to pay attention to control the reaction conditions to prevent the formation of polyhalides and affect the purity and yield of the product.
Second, 2,5-difluorobenzoic acid can be used to reduce it first. It is common to react with strong reducing agents, such as lithium aluminum hydride (LiAlH), in suitable organic solvents (such as anhydrous ether, tetrahydrofuran), which can reduce the carboxyl group to a hydroxyl group, and then prepare the target product 2,5-difluorobenzyl alcohol. This method has high reduction efficiency, but lithium aluminum hydride is active in nature, and the reaction operation requires strict requirements. It needs to be carried out in an anhydrous and anaerobic environment, and the post-treatment also needs to be careful to ensure safety and separation of the product.
Third, with the help of Grignard reagent method. First prepare Grignard reagents containing 2,5-difluorophenyl, such as 2,5-difluorobromobenzene and magnesium chips in anhydrous ether or tetrahydrofuran, and then react with formaldehyde or paraformaldehyde to obtain 2,5-difluorobenzyl alcohol after hydrolysis. This approach requires strict control of the preparation conditions of Grignard reagents and an anhydrous environment as the key, otherwise Grignard reagents are prone to failure. And during the reaction process, the proportion of reagents, reaction temperature and other factors also need to be precisely regulated to obtain ideal results.
What are the precautions for using 2,5-dichlorofluorobenzene?
2% 2C5-difluoroethane is commonly used in chemical industry. When using it, many matters need to be paid attention to.
Bear the brunt, safety is the most important thing. This substance is flammable, and it is easy to burn and explode in case of open flames and hot topics. Therefore, in the place of use, fireworks are strictly prohibited, and suitable fire extinguishing equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc., should be equipped for emergencies. At the same time, its steam is heavier than air and can spread to a considerable distance at a lower place. In case of fire source, it will catch fire and backfire, so the use site must be well ventilated to prevent steam accumulation and cause danger.
Furthermore, it is related to human protection. Because of its irritating effect on the eyes and respiratory mucosa, users need to take protective measures. Appropriate protective glasses should be worn to prevent liquid from splashing into the eyes and causing damage; gas masks should also be worn to avoid inhaling steam and damaging the respiratory tract. If you accidentally come into contact with the skin, you should immediately take off the contaminated clothes and rinse with a lot of flowing water for at least 15 minutes; if you come into contact with the eyes, you need to immediately lift the eyelids, rinse thoroughly with a lot of flowing water or normal saline for at least 15 minutes, and seek medical attention in time.
In addition, storage is also exquisite. It should be stored in a cool and ventilated warehouse, away from fire and heat sources, and the storage temperature should not exceed 30 ° C. And it should be stored separately from oxidants and acids, and mixed storage should not be avoided. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials. If any leakage occurs, it can be properly handled in a timely manner to prevent the expansion of the hazard.
In short, when using 2% 2C5-difluoroethane, it is necessary to be cautious and strictly follow safety procedures to ensure personal safety and environmental safety.