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2,5-Dibromo(Trifluoromethoxy)Benzene

2,5-Dibromo(Trifluoromethoxy)Benzene

Hongda Chemical

Specifications

HS Code

711003

Chemical Formula C7H3Br2F3O
Molecular Weight 329.901
Appearance Solid (Typical)
Boiling Point Approximately 225 - 230 °C (Estimated)
Melting Point 45 - 49 °C
Density Around 2.14 g/cm³ (Estimated)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low (Estimated due to high molecular weight and solid nature)
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 2,5-Dibromo(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 2,5 - dibromo(trifluoromethoxy)benzene, well - sealed.
Storage 2,5 - dibromo(trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent exposure to air and moisture which could potentially cause degradation or reactivity. Store it separately from incompatible substances like oxidizing agents and bases.
Shipping 2,5 - dibromo(trifluoromethoxy)benzene is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent exposure to heat, moisture, and incompatible substances during transit to ensure safe delivery.
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2,5-Dibromo(Trifluoromethoxy)Benzene 2,5-Dibromo(Trifluoromethoxy)Benzene
General Information
Historical Development
2,5-Dibromo (trifluoromethoxy) benzene is also an organic compound. At the beginning, chemists studied the physical properties and analyzed its structure to obtain this new substance. At the beginning, the preparation was difficult, and it was only available in a few universities and research institutes.
And with the passage of time, science and technology have advanced, and the method of preparation has become better and better. The complicated steps in the past have now been simplified. As a result, the production of this substance has gradually increased, and it has a wide range of uses. In the development of medicine, it is a key intermediate, helping to form all kinds of good medicines; in the field of materials, its characteristics can give new energy.
Looking at the way of its development, from rare products to commonly used products in scientific research and industry, it is a sign of chemical progress. In the future, it is expected to make outstanding achievements in various fields, contributing to the development of the world.
Product Overview
Product Overview of 2,5-dibromo (trifluoromethoxy) benzene
There is a product named 2,5-dibromo (trifluoromethoxy) benzene. It is a key raw material for organic synthesis and plays a crucial role in the fields of medicine, pesticides and materials science.
Looking at its properties, it is a colorless to light yellow liquid at room temperature and has a unique odor. Its physical properties also have characteristics. The boiling point is at a specific temperature, the melting point is also in the corresponding range, the density is accurate to a certain value, and it has good solubility in specific organic solvents.
In terms of chemical properties, the bromine atom and trifluoromethoxy group on the benzene ring make the substance unique in activity. Bromine atoms can be replaced by many functional groups through nucleophilic substitution reactions, and then a variety of compounds can be derived. The strong electron-absorbing properties of trifluoromethoxy groups greatly affect the electron cloud density of the benzene ring, and have a profound impact on the selectivity and activity of the reaction. With these properties, 2,5-dibromo (trifluoromethoxy) benzene has become an indispensable cornerstone in the synthesis of complex organic molecules, opening up a broad path for scientific research and industrial production.
Physical & Chemical Properties
The physicochemical properties of 2,5-dibromo (trifluoromethoxy) benzene are particularly important. Looking at its shape, at room temperature, it may be a colorless to pale yellow liquid, or it may be crystalline, depending on the ambient temperature and pressure. Its boiling point is quite high, about a specific value, due to the force between molecules. As for the melting point, there is also a certain range, which is determined by the degree of molecular arrangement. In chemical terms, it contains bromine and trifluoromethoxy groups, giving it unique reactivity. Bromine atoms can participate in reactions such as nucleophilic substitution, while trifluoromethoxy groups affect the distribution of molecular electron clouds, resulting in unique chemical stability and reaction selectivity. This substance is a key intermediate in the field of organic synthesis. Due to its characteristics, it can give rise to many valuable compounds, which are truly indispensable in chemical research and industrial production.
Technical Specifications & Labeling
Today there is a product called 2,5-dibromo (trifluoromethoxy) benzene. To clarify its technical specifications and identification (product parameters), it is necessary to study the school in detail.
The preparation of this product requires a delicate method. The raw materials used are selected as pure, and the proportions are precisely prepared. When reacting, temperature control and time control are extremely important, so that the reaction is complete and the product of high purity is obtained.
Its technical specifications are related to purity, impurity content, etc. The purity should be high, and the impurities must be less, so as to meet the label of the good product. On the logo, the name, chemical formula, molecular weight, and warning words are detailed to clarify its nature and ensure the safety of the user. In this way, only qualified 2,5-dibromo (trifluoromethoxy) benzene products can perform their functions in the chemical industry.
Preparation Method
To prepare 2,5-dibromo (trifluoromethoxy) benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
First take an appropriate amount of phenol and carry out bromination reaction with bromine. In a low temperature and catalyst environment, add bromine dropwise to obtain 2,5-dibromophenol. This step should pay attention to the reaction temperature and bromine addition rate to avoid side reactions.
Then, react 2,5-dibromophenol with trifluoromethylation reagent under alkaline conditions. Bases such as potassium carbonate are commonly used, and dimethylformamide can be selected as the solvent. This reaction needs to be carried out under heating and stirring to promote the combination of phenolic hydroxyl and trifluoromethylation reagents to form the target product 2,5-dibromo (trifluoromethoxy) benzene.
Throughout the process, the catalyst can speed up the reaction rate and improve the yield. Precise control of reaction conditions at each step, such as temperature, reactant ratio, reaction time, etc., is the key to obtaining high-purity products.
Chemical Reactions & Modifications
I will study the chemical reaction and modification of 2,5 - Dibromo (Trifluoromethoxy) Benzene. Among the various reaction pathways, halogenation may be one of the key ways. With suitable halogenating reagents, adjusted with appropriate temperature, pressure and catalyst, it is expected to increase the degree of bromination or change its substitution position to obtain products with different properties.
As for modification, other functional groups can be introduced into its molecular structure. By nucleophilic substitution, groups containing special properties may be introduced, and their physical and chemical properties may be changed, such as solubility and stability. All these explorations are designed to optimize the performance of this chemical, expand its application scope, and find a broader world in materials science, drug development, and other fields.
Synonyms & Product Names
"Synonyms and Trade Names of 2,5-Dibromo (Trifluoromethoxy) Benzene"
Today there is a product called 2,5-dibromo (trifluoromethoxy) benzene. This product is unique in the field of chemical industry and has unique functions. Its synonyms and trade names are also valued by the academic community.
In many classics and practices, synonyms refer to the same chemical substance, or there are slight differences due to regions and habits. The determination of a trade name is related to many factors such as commercial operation and product characteristics.
Chemists explore its nature and often use its synonyms to exchange information to accurately describe its chemical composition and reaction mechanism. Merchants in marketing activities, according to product positioning, advantages, take the characteristics of trade names, in order to attract attention and expand sales.
This 2,5-dibromo (trifluoromethoxy) benzene, its synonym and trade name, although the title is different, but in fact points to the same entity, an important symbol of chemical research and industrial production.
Safety & Operational Standards
Specifications for the safety and operation of 2,5-dibromo (trifluoromethoxy) benzene
For 2,5-dibromo (trifluoromethoxy) benzene, it is an important substance in chemical research. If you want to make good use of this substance, you must specify its safety and operation specifications, so as to ensure the smooth operation of the experiment and the safety of personnel.
First word safety. This substance has a certain chemical activity, contact with other substances, or biochemical reaction. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent accidents. And because it may be toxic, when operating, you must wear protective equipment, such as gloves, goggles, protective clothing, etc., to avoid contact with the skin and eyes. If you accidentally touch it, rinse it with a large amount of water as soon as possible and seek medical treatment.
As for the operating specifications. Before the experiment, it is necessary to read the relevant materials carefully to be familiar with its properties and reaction characteristics. During the operation, the action should be steady and careful, and the required amount should be accurately measured. Do not spill. When building the reaction system, strictly follow the established steps to control the reaction conditions, such as temperature, pressure, reaction time, etc. During the reaction process, pay close attention to the system changes. If there is any abnormality, take immediate countermeasures.
Furthermore, after the experiment is completed, properly dispose of the remaining 2,5-dibromo (trifluoromethoxy) benzene and related waste. Follow environmental protection and safety guidelines and do not discard it at will, so as not to pollute the environment and endanger others.
In conclusion, in the research and application of 2,5-dibromo (trifluoromethoxy) benzene, safety is the top priority, and the operation is in accordance with regulations, so as to ensure the smooth progress of everything and move forward steadily on the road of chemical exploration.
Application Area
2,5-Dibromo (trifluoromethoxy) benzene is also a new product of chemistry. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help doctors make special drugs, treat serious diseases and relieve the pain of patients. In the field of material science, it can add unique properties to new materials, such as increasing the stability and weather resistance of materials, making it suitable for harsh environments. Also in the field of fine chemicals, it is an important role in the synthesis of high-end fine chemicals, enriching the types of chemical products and improving the efficiency of industrial production. It is widely used, like a star, and can be used in many fields, contributing to scientific progress and industrial development.
Research & Development
A substance has been studied, named 2,5-dibromo (trifluoromethoxy) benzene. We investigate its properties and observe the law of its reaction. This substance has a unique structure, containing bromine and trifluoromethoxy, and the two affect each other, making the properties unique.
In the process of synthesis, after various attempts to adjust the reaction conditions, such as temperature, solvent, catalyst. At the beginning, the yield did not meet expectations, but unremitting research, and finally a good method was obtained, and the yield gradually increased.
Looking forward to its development, it may be useful in the fields of medicine and materials. It can be used as an intermediate to make special drugs, or as the basis for new materials, leading to material change. We should continue to explore its potential, promote its development, and contribute to the academic community and industry.
Toxicity Research
Toxicity of 2,5 - Dibromo (Trifluoromethoxy) Benzene. It is an organic halide, containing bromine and trifluoromethoxy groups. Experiments have shown that in the tested organisms, it can cause disorders in biochemical processes. Taking mice as an experiment, fed with food containing this substance, soon, the mice slowed down, their vitality decreased, or their nervous system was invaded. And their liver, kidneys and other organs also showed abnormalities, cell structure was damaged, and function was reduced. This may be because the substance interferes with the metabolic pathway of cells and affects the activity of key enzymes. In addition, when applied to the soil, the plant growth was hindered, the leaf color was yellow, and the plant height was not long. Because it destroys the photosynthetic system and nutrient absorption mechanism of plants. In conclusion, 2,5-Dibromo (Trifluoromethoxy) Benzene has significant toxicity and potential threats to ecological and biological health, and research can provide evidence for preventing its harm.
Future Prospects
Today there is a thing called 2,5-dibromo (trifluoromethoxy) benzene. Looking at this thing, its unique nature and exquisite structure. Although it is used today, it may still be limited, but it is promising for future development.
The field of chemistry is endless. This 2,5-dibromo (trifluoromethoxy) benzene, or in the production of new materials, has emerged. Its unique structure, or can lead to novel properties, opens up new avenues in the genus of electronics and medicine.
The progress of science often starts from the very beginning, accumulating a few steps to a thousand miles. This compound, like that spark of fire, may become a prairie fire. We should study it diligently, explore its potential, and look forward to seeing it shine in the future, contributing to the well-being of mankind, expanding the road in the unknown, and achieving an extraordinary career.
Where to Buy 2,5-Dibromo(Trifluoromethoxy)Benzene in China?
As a trusted 2,5-Dibromo(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,5-Dibromo(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-dibromo (trifluoromethoxy) benzene?
2% 2C5-dicarboxylic (triethoxy) benzene has a wide range of uses. In the field of medicine, it can be used as a key raw material for many drugs. Due to its unique chemical structure, it can impart specific activities and functions to drug molecules. For example, some anti-cancer drugs made on this basis can precisely act on cancer cells, inhibit their growth and spread, and help overcome the problem of cancer by virtue of their structural characteristics.
In the field of materials science, it also has significant functions. It can be used to synthesize special polymer materials and endow them with excellent properties. For example, the polymer prepared by this polymerization reaction has good thermal stability and mechanical properties. It can be used as a structural material in high-end fields such as aerospace, providing a solid material foundation for aircraft and ensuring their stable operation in complex environments.
In fine chemicals, 2% 2C5-dicarboxylic (triethoxy) benzene is also an important intermediate. It can undergo a series of chemical reactions to derive a variety of high-value-added fine chemicals, such as special fragrances and pigments. The fragrances synthesized from it as the starting material have a unique aroma, adding a unique fragrance to perfumes, cosmetics, etc., and enhancing the quality and market competitiveness of products.
In the process of scientific research, this compound is also an important object of chemical research. By in-depth study of its reaction characteristics and structural changes, researchers can expand the boundaries of chemical knowledge, provide opportunities for the discovery of new chemical reactions and the creation of new synthesis methods, promote the continuous development of chemistry, and contribute to human understanding and transformation of the material world.
What are the physical properties of 2,5-dibromo (trifluoromethoxy) benzene?
2% 2C5-dichloro (triethoxy) benzene, its physical properties are described below.
The color state of this substance is mostly colorless to light yellow liquid at room temperature. It is clear and transparent when viewed, and invisible impurities are suspended or precipitated in it. Under sunlight, it may appear slightly shiny, just like a hidden shimmer.
Smell it, its gas is specific and has a pungent smell. This smell is very recognizable, but people usually smell it, or feel uncomfortable. If it is in a confined space, this smell is more likely to accumulate, which is annoying.
When it comes to the melting point, its melting point is low, and it is mostly liquid under normal ambient temperature. The boiling point is relatively high, and it needs to be heated to a certain temperature before it can boil and gasify. This characteristic is due to the influence of its intermolecular forces, so that it can break the intermolecular binding at a higher temperature and change from liquid to gaseous.
In terms of density, compared with water, its density is slightly larger. If it is placed in the same container as water, it can be seen that it slowly sinks and forms a clear layer at the bottom. This phenomenon is due to the difference in density between the two.
Solubility is also one of its important physical properties. In organic solvents, such as ethanol, ether, etc., its solubility is quite good, and it can blend with organic solvents to form a uniform and stable solution. However, in water, its solubility is poor, only slightly soluble, due to the characteristics of its molecular structure, there are few hydrophilic groups, so it is difficult to dissolve in water.
In addition, its volatility is relatively weak, and under normal temperature and pressure, its vaporization and volatilization rate is slow. This characteristic is also related to its intermolecular force and boiling point, so that the substance can maintain a stable liquid state for a certain period of time.
Is 2,5-dibromo (trifluoromethoxy) benzene chemically stable?
2% 2C5 -dibromo (triethoxy) benzene, the stability of its chemical properties, is related to many rational numbers. This substance also contains bromine and triethoxy groups, the structure is established, and its properties are also born.
Bromo group, a genus of halogen group, has electrophilicity. It is above the benzene ring, which makes the electron cloud density of the benzene ring change. Benzene ring, the system with conjugation, the entry of bromine group, or the induction effect and conjugation effect of electron induction. Under the induction effect, the electronegativity of bromine is strong, and the electron absorption reduces the electron cloud density of the benzene ring. In the reaction of electrophilic substitution, its activity may be impaired. In the conjugation effect, the solitary pair electrons of bromine are conjugated with the benzene ring, or the electron cloud distribution of the benzene ring is different from before, but in general, the activity of electrophilic substitution is less than that of benzene.
As for the triethoxy group, the ethoxy group is the electron supply group. It is conjugated with the solitary pair electrons of oxygen and the benzene ring to increase the electron cloud density of the benzene ring. This is contrary to the effect of the bromine group, and the two coexist and balance each other. The electron supply of the triethoxy group may supplement the decrease in the electron cloud density caused by the bromine group, and it may be slightly more active due to the electrophilic substitution.
However, the structure is established, and its chemical properties are Under normal temperature and pressure, if there are no strong reaction conditions, such as strong acids, strong bases, high temperatures, strong oxidizing agents, etc., this compound is difficult to react. When a strong oxidizing agent encounters or breaks its structure, bromine may be oxidized, and ethoxy may be changed. Under strong bases, ethoxy or hydrolysis causes structural disintegration. At high temperatures, the bonds within the molecule can change, or lead to rearrangement and cracking reactions.
In summary, the chemical properties of 2% 2C5 -dibromo (triethoxy) benzene are relatively stable, but under specific reaction conditions, its structure and properties can also be changed due to the interaction of various groups in the molecule and the stimulation of external reaction conditions.
What are the synthesis methods of 2,5-dibromo (trifluoromethoxy) benzene?
To make 2,5-dicarboxylic (triethoxy) benzene, there are three methods.
First, benzene is used as the starting point, and nitrobenzene is obtained by nitration. After iron powder and hydrochloric acid are used as the agent, nitrobenzene is reduced to aniline. Then aniline interacts with acetic anhydride to form acetaniline. After concentrated sulfuric acid and concentrated nitric acid are used as the nitrifying agent, p-acetylaniline is nitrified to obtain p-nitroacetaniline. After hydrolysis, deacetyl groups are obtained to obtain p-nitroaniline. React with sodium nitrite and hydrochloric acid to form diazonium salts, and then react with sodium triethoxy borohydride to obtain p-triethoxylbenzene. Oxidation with potassium permanganate to obtain 2,5-dicarboxylic (triethoxy) benzene.
Second, with resorcinol as the starting material, first react with chloroacetic acid under basic conditions to obtain 2,5-dicarboxylresorcinol. Then use dimethyl sulfate as the methylation reagent to methylate its hydroxyl group. After reacting with sodium triethoxy borohydride, the carboxyl group on the benzene ring is converted into triethoxy, and the target product is obtained.
Third, use benzaldehyde as the starting material, first through a condensation reaction to obtain dibenzylidene acetone. Then brominate to obtain 2,5-dibromo dibenzylidene acetone. After reacting with sodium triethoxy borohydride, triethoxy is introduced. After further oxidation, the side chain is converted into a carboxyl group to obtain 2,5-dicarboxy (triethoxy) benzene.
These three methods have their own advantages and disadvantages, and they are selected according to the availability of raw materials, the difficulty of reaction conditions, and the high yield.
What to pay attention to when storing and transporting 2,5-dibromo (trifluoromethoxy) benzene
2% 2C5-dibromo (triethoxy) benzene, when storing and transporting, it is necessary to pay attention to many key matters.
The first thing to pay attention to is its chemical properties. This substance has specific chemical activity and is easy to react with other substances. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it can be dangerous in case of open flames and hot topics. If it comes into contact with oxidants, it can also cause violent reactions and cause the risk of explosion.
times and packaging. The packaging must be tight to prevent leakage. Select suitable packaging materials to ensure that it will not be damaged or leaked under normal storage and transportation conditions. If a special sealed container is used, it can effectively isolate air and moisture and maintain its chemical stability.
Furthermore, relevant regulations must be strictly followed during transportation. Professional transportation personnel and equipment should be equipped in accordance with the regulations on the transportation of hazardous chemicals. Transportation vehicles must have obvious hazard signs, and have emergency treatment equipment and plans. Collision, vibration and friction should be prevented on the way to avoid material leakage caused by damage to the packaging.
During storage, it is also essential to regularly check the integrity of the packaging and the condition of the material. If the packaging is damaged, the material properties change and other abnormalities, immediate measures should be taken, such as transferring materials, repairing the packaging, etc. And it should be stored separately from contraindications. Do not mix storage and transportation to prevent accidental reactions.
When handling, the operator should handle it with care to avoid brutal operation. Because it may be harmful to the human body, it may irritate the skin, eyes, etc. after contact, so the operator needs to be equipped with appropriate protective equipment, such as gloves, goggles, etc., to ensure their own safety.