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2,5-Bis(Trifluoromethyl)Nitrobenzene

2,5-Bis(Trifluoromethyl)Nitrobenzene

Hongda Chemical

Specifications

HS Code

226170

Chemical Formula C8H3F6NO2
Molecular Weight 261.106
Appearance Yellow liquid
Boiling Point 188 - 190 °C
Melting Point 16 - 17 °C
Density 1.58 g/cm³
Solubility In Water Insoluble
Vapor Pressure Low
Flash Point 83 °C
Refractive Index 1.427

As an accredited 2,5-Bis(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,5 - bis(trifluoromethyl)nitrobenzene packaged in a sealed glass bottle.
Storage 2,5 - bis(trifluoromethyl)nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. Also, ensure proper labeling for easy identification and safety compliance.
Shipping 2,5 - bis(trifluoromethyl)nitrobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken due to its chemical nature. Shipment adheres to strict hazardous materials regulations to ensure safety during transit.
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2,5-Bis(Trifluoromethyl)Nitrobenzene 2,5-Bis(Trifluoromethyl)Nitrobenzene
General Information
Historical Development
2,5-Bis (trifluoromethyl) nitrobenzene is also a genus of chemical products. At the beginning, the researchers devoted themselves to exploring its properties and seeking its methods. At the beginning, the road of synthesis was full of thorns, the raw materials were rare, the steps were complicated, and the yield was quite low. However, the sages were not discouraged, and they worked hard. Over the years, the techniques have gradually refined. From the crude method of the past, it has evolved to the exquisite technique of today. The yield is rising day by day, and the quality is better. Looking at its course, it is like sailing against the current, and you will progress with perseverance. The difficulties of the past are the foundation of today's smooth road. Since its inception, it has emerged in various fields and has become more and more widely used. This is all due to the efforts of researchers of all dynasties. They have worked tirelessly to finally make this product brilliant and occupy a place in the forest of chemistry, paving the way for the development of future generations.
Product Overview
2,5-Bis (trifluoromethyl) nitrobenzene, an organic compound. It may be a colorless liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis.
The method of its preparation is often determined by the chemical reaction. With appropriate raw materials and delicate steps, it may be obtained. During the reaction process, various conditions, such as temperature, pressure, and catalyst, need to be precisely controlled to achieve the ideal yield and purity.
2,5-Bis (trifluoromethyl) nitrobenzene has potential value in many fields such as pharmaceutical chemistry and materials science. In pharmaceutical research and development, it may be a key intermediate for the creation of new drugs; in the field of materials, it may assist in the development of materials with special properties. However, it also needs to be properly disposed of because it may be toxic and dangerous. When operating, strict safety procedures must be followed to ensure the safety of personnel and the environment.
Physical & Chemical Properties
2,5-Bis (trifluoromethyl) nitrobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, it is mostly liquid at room temperature, with a clear color and a specific taste. The boiling point is quite certain, which is related to the conditions of its gasification. Density also has characteristics and plays a significant role in related systems.
On its chemical properties, the presence of nitro and trifluoromethyl makes it have unique reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction is not easy. And trifluoromethyl is also a strong electron-absorbing group, and the synergy between the two makes this compound special in many reactions. Its chemical stability also needs to be studied in detail, under different media, temperatures, or changes.
Technical Specifications & Labeling
In 2024, the research of various compounds in the field of chemistry is crucial. Today, the technical specifications and labeling (product parameters) of 2,5-bis (trifluoromethyl) nitrobenzene are discussed.
The preparation of this compound requires a precise process. In the reaction system, the raw material ratio is rigorous, and the reaction is under specific temperature and pressure. For example, the molar ratio of the reactant needs to be precisely controlled, and the temperature is controlled within a certain range to ensure that the reaction is efficient and the product is pure.
In terms of its labeling, the name "2,5-bis (trifluoromethyl) nitrobenzene" should be clearly marked, indicating the molecular formula and molecular weight. Hazardous characteristics should also be clearly indicated, because of its specific chemical activity, there are strict requirements for contact and storage. Packaging labels should comply with relevant regulations to ensure safe transportation and use, which are the key to the technical specifications and labels of the product, and are related to the orderly advancement of production and application.
Preparation Method
The method of making 2,5-bis (trifluoromethyl) nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected and the purity is high. In the production process, first take an appropriate amount of fluorine-containing reagents and nitrobenzene derivatives, put them in a special reactor, adjust them to a suitable temperature, about one hundred and twenty degrees Celsius, and control the pressure at three to five standard atmospheric pressures. Use precious metal complexes as catalysts to accelerate the reaction process.
The reaction steps are strict, first mix the raw materials, fully stir them evenly, and then slowly heat up to closely observe the reaction situation. When the reaction is stable, maintain this state for about three hours. The catalytic mechanism is the ingenious effect of the catalyst and the reactants, which reduces the activation energy of the reaction and promotes the efficient progress of the reaction. Pure 2,5-bis (trifluoromethyl) nitrobenzene product was obtained by fine separation and purification after reaction.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 2,5-Bis (Trifluoromethyl) Nitrobenzene. As a chemical researcher, I often study chemical reactions and modifications. The chemical reactions of this substance are related to many reaction mechanisms. To obtain a good effect, it is necessary to consider the reaction conditions in detail, such as temperature, pressure, and catalyst genus. High or low temperature affects the reaction rate and product purity; improper pressure can also lead to reaction biases.
As for modification, it is to optimize its performance. Or change its molecular structure to increase its stability; or adjust its chemical activity to make it suitable for different scenarios. When modifying, it is necessary to weigh the advantages and disadvantages and take into account all aspects of properties. In this way, 2,5-Bis (Trifluoromethyl) Nitrobenzene can play a greater role in the chemical industry, materials and other fields, for the well-being of the world, and also promote the progress and development of chemistry.
Synonyms & Product Names
2,5-Bis (trifluoromethyl) nitrobenzene, the nickname and trade name of this substance, is worth discussing. In the field of my chemical research, exploring its various names is like exploring the hidden treasures in ancient books.
Its nickname may be derived from its structural properties, describing its molecular structure in precise chemical terms, so that people in the industry can know it. The formulation of the trade name may be related to commercial promotion and market awareness, hoping to make it stand out among various chemicals with a unique name.
Considering the process of chemical research in the past, the names of many compounds have changed with the changes of the times and the deepening of research. 2,5-Bis (trifluoromethyl) nitrobenzene may also be referred to at different stages through this journey, imprinting the research level and cognitive limitations at that time.
Our generation of chemical researchers should use a rigorous attitude to sort out the context of their nicknames and trade names, and clarify their origins, so as to help this chemical move forward smoothly in scientific research, industrial applications, etc., to avoid confusion and errors due to appellations, and also to make a modest contribution to the inheritance and expansion of chemical knowledge.
Safety & Operational Standards
Specifications for the safety and operation of 2,5-bis (trifluoromethyl) nitrobenzene
F 2,5-bis (trifluoromethyl) nitrobenzene is an important chemical compound in chemical research. Safety and operating standards are of paramount importance during its experimental preparation and use.
First word safety. This compound has certain chemical activity and potential hazards. It should be stored in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Due to heat or contact with strong oxidants, it may cause violent chemical reactions, resulting in fire or explosion. When taking it, the experimenter must wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent it from coming into contact with the skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to the specific situation.
Times and operating specifications. During the experimental operation, relevant operations should be carried out in the fume hood to ensure that the volatile gas can be discharged in time to avoid the experimenter inhaling harmful gases. The experimental equipment should be clean and dry to prevent impurities from affecting the reaction process or adverse reactions with the compound. During the reaction, the reaction conditions, such as temperature, pressure and ratio of reactants, should be strictly controlled. If the temperature is too high or too low, the reaction may be out of control or the product is impure. In addition, the waste after the reaction cannot be discarded at will, and it needs to be properly disposed of in accordance with relevant regulations to prevent environmental pollution.
In conclusion, in the research and application of 2,5-bis (trifluoromethyl) nitrobenzene, strict adherence to safety and operating standards can ensure the smooth progress of the experiment, and ensure the safety of the experimenter and the safety of the environment.
Application Area
2,5-Bis (trifluoromethyl) nitrobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and cure various diseases. In the field of materials science, it also has important functions, which can contribute to the creation of new functional materials, so that the materials can obtain specific properties, such as better stability or unique optical properties.
Furthermore, in the fine chemical industry, this compound is often the cornerstone of the synthesis of special chemicals, giving the product different quality and use. Its application in many fields is constantly expanding and deepening, making great contributions to the progress of science and technology and the development of industry. It is indeed a highly valuable chemical substance, and its future application prospects are also very broad.
Research & Development
I have been dedicated to the research and development of 2,5-bis (trifluoromethyl) nitrobenzene for a long time. This compound has unique characteristics and has a wide range of applications. I have studied its synthesis method in detail, improved the existing process, and hoped to increase the yield and reduce the cost. After repeated experiments, the reaction conditions were optimized, the suitable catalyst was selected, and the precise temperature and pressure were controlled, so that the synthesis process was smoother. And explore its potential applications in the fields of materials science and drug development. Examine its reactivity with other substances and find ways to expand its use. With my research, I hope to promote this compound to shine in various fields, contribute to the progress of scientific research and industry, and promote it from the laboratory to a wider practical world, so as to maximize its value.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons should not be careless. Now, the toxicity of 2,5-bis (trifluoromethyl) nitrobenzene is quite important.
This chemical is highly toxic. Between experimental studies, observe its impact on various things. Touch the skin, or make the skin sick, such as rashes like sores, very painful; enter the mouth and nose, invade the organs, cause qi and blood disorders, and stagnation of respiration.
And in the environment, its toxicity should not be underestimated. Or dirty the soil, make plants and trees not flourish; or dye the water, harm the aquatic life. Therefore, to study its toxicity, we need to be cautious, scrutinize its nature, and explore the depth of its harm. In order to avoid it, we hope to ensure the safety of everyone and protect the tranquility of the environment. Do not let this poison ravage and leave a disaster in the world.
Future Prospects
In today's view, 2,5-bis (trifluoromethyl) nitrobenzene is unique and has a wide range of uses. Although the world may have undiscovered its research and use at present, our generation of chemical researchers are full of hope for its future development.
In the field of organic synthesis, this substance may become a key reagent and help many delicate reactions to be realized. In the field of materials science, it may be cleverly designed to be used as a primitive for the construction of novel materials, adding brilliance to the properties of materials. And it is in the development of medicine all the way, or it may hide infinite possibilities, or it may be an opportunity to find new drugs with special effects.
We should study it diligently and explore its mysteries in depth with scientific methods. With time, it will be able to make its potential fully realized, shining brightly for the well-being of mankind and the advancement of science and technology, unfolding its unfinished grand path, and becoming a grand sight of the future.
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Frequently Asked Questions

As a leading 2,5-Bis(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-bis (trifluoromethyl) nitrobenzene?
2% 2C5 -Bis (triethoxypropyl) silane, which has a wide range of uses. In the construction field, it can be used as a waterproof agent, because it can penetrate into the interior of building materials, chemically react with the substrate, and generate a waterproof and hydrophobic structure, which greatly improves the water resistance of buildings. After being treated with concrete, masonry and other materials, the waterproof effect is outstanding, which can effectively resist rainwater erosion and prolong the service life of buildings.
In the field of composite material manufacturing, it is an excellent coupling agent. It can improve the interfacial bonding force between inorganic materials and organic polymer materials, so that the two with poor compatibility are closely connected. Taking glass fiber reinforced plastics as an example, after being treated, the glass fiber and the resin matrix are more firmly bonded, and the mechanical properties of the composite material are significantly enhanced, such as strength and toughness.
In the coating industry, it can be used as an additive. It can improve the adhesion of the coating to the substrate, so that the coating adheres more firmly to the surface of the object, and is not easy to fall off; at the same time, it can enhance the weather resistance, wear resistance and other properties of the coating, prolong the service life of the coating, and keep the coating in good condition for a long time.
In the field of electronics industry, it also plays an important role. Adding it to the packaging materials of electronic components can enhance the bonding force between the packaging materials and electronic components, improve the stability and reliability of electronic components, and ensure the stable operation of electronic equipment.
Overall, 2% 2C5-bis (triethoxypropyl) silane has critical uses in multiple industries and has made significant contributions to promoting the development of various industries.
What are the physical properties of 2,5-bis (trifluoromethyl) nitrobenzene?
2% 2C5 -Bis (triethoxysilyl) propyl ether, the physical properties of this substance are as follows:
Under normal temperature and pressure, its appearance is often colorless and transparent liquid, clear and free of impurities, with a certain fluidity. Looking at its color, it is almost colorless as water, and is extremely pure.
When it comes to odor, it emits a weak and special organic smell, which is not pungent and unpleasant. It is relatively mild, but its unique chemical characteristics can still be detected by a fine smell.
In terms of density, it is relatively stable, slightly higher than the density of water. This property makes it exist in a liquid state, and under specific conditions, it will be mixed with substances with different densities such as water, showing a specific stratification phenomenon. The boiling point of
is quite considerable, and a higher temperature is required to convert it from liquid to gaseous. This boiling point characteristic, in the process of industrial separation and purification, can be effectively separated from the mixture by precisely controlling the temperature to achieve the purpose of purification.
The melting point is lower, and it is far from the melting point range at room temperature, so it is stable to maintain the liquid state. The characteristics of this low temperature melting point can still ensure its fluidity in cold environments, and it is not easy to solidify due to low temperature, resulting in unlimited use.
In terms of solubility, it can be well miscible with most organic solvents, such as ethanol, acetone, etc. This solubility provides great convenience for its application in organic synthesis, coatings, adhesives and other fields, and can be uniformly mixed with a variety of organic components to exert synergy effect.
2% 2C5 -bis (triethoxysilyl) propyl ether occupies an important position in many fields of chemical industry due to its unique physical properties. It is a key raw material for material modification, organic synthesis and other operations.
Is the chemical properties of 2,5-bis (trifluoromethyl) nitrobenzene stable?
2% 2C5-bis (triethylamino) pyridine, which has relatively stable chemical properties.
2% 2C5-bis (triethylamino) pyridine, which contains specific groups in its structure, endows it with unique chemical properties. Triethylamino is the donator group, which enhances the electron cloud density of the pyridine ring, causing its chemical activity to show a specific trend.
From the perspective of reactivity, the pyridine ring is nucleophilic and can react with electrophilic reagents. However, due to triethylamino steric resistance and electronic effects, the reaction selectivity and rate are affected. In many organic reaction environments, 2% 2C5-bis (triethylamino) pyridine can be used as a base or ligand.
When used as a base, due to the alkalinity of triethylamino, it can participate in acid-base reactions, capture protons, and stabilize the system. In the field of coordination chemistry, pyridine cyclic nitrogen atoms can be used as coordination atoms to complex with metal ions to form stable complexes.
and 2% 2C5 -bis (triethylamino) pyridine molecular structure rigidity and steric resistance make the molecular configuration relatively stable, and it is not easy to be disturbed by external minor factors and drastic changes. In addition, the chemical bonds contained in the bond energy adaptation, under common conditions, the chemical bonds are difficult to spontaneously break and recombine, thus showing a stable state of chemical properties.
What are the synthesis methods of 2,5-bis (trifluoromethyl) nitrobenzene?
The synthesis of 2% 2C5 -bis (triethylamino) naphthol is an important topic in the field of organic synthesis. There are many methods for its synthesis, and the following are several common methods.
One is the nucleophilic substitution method. First, naphthol is taken as the starting material and reacted with suitable halogenated alkanes, such as triethylamine halide, under basic conditions. The function of the base is to capture the hydrogen of the hydroxy group of naphthol, enhance its nucleophilicity, and then undergo nucleophilic substitution with halogenated alkanes to form the target product. This process requires strict control of the reaction temperature, time and the ratio of reactants to prevent side reactions from occurring and affecting the yield.
The second is the metal catalysis method. Suitable metal catalysts, such as palladium and copper, are selected to promote the reaction between naphthol and reagents containing triethylamino groups. Metal catalysts can activate the reactants, reduce the activation energy of the reaction, and accelerate the reaction process. For example, when catalyzed by palladium catalysts, the reactants are more likely to react under specific conditions by forming metal-ligand complexes. However, the cost of metal catalysts is higher, and the separation and recovery after the reaction also need special consideration.
The third is the condensation reaction method. Naphthol derivatives and triethylamine derivatives are used to construct target molecules through condensation reactions. This process often requires the participation of specific condensing agents, such as carbodiimide condensing agents. The condensation agent can promote the smooth progress of the reaction, so that the functional groups of naphthol and triethylamine derivatives can undergo condensation reactions such as dehydration or dehalogenation, and the synthesis of 2% 2C5-bis (triethylamino) naphthol can be achieved. However, the condensation reaction conditions are relatively harsh, and the requirements for anhydrous and anaerobic reaction systems are quite high.
The above synthetic methods have their own advantages and disadvantages. In practical applications, appropriate synthetic methods should be carefully selected according to specific conditions, such as raw material availability, cost considerations, product purity requirements, etc., in order to achieve efficient, economical and environmentally friendly synthesis goals.
What are the precautions for storing and transporting 2,5-bis (trifluoromethyl) nitrobenzene?
2% 2C5 -Bis (triethylamino) quinoline should pay attention to the following matters during storage and transportation:
First, when storing, it should be in a cool and dry place. This substance is quite sensitive to humidity. If the storage environment is humid, water vapor will easily react with it, which will change its chemical properties and cause deterioration. Therefore, the humidity in the warehouse should be strictly controlled within a specific range to prevent moisture.
Second, temperature control is also crucial. High temperature environments should be avoided, because high temperature may enhance the molecular activity of the substance, causing reactions such as decomposition or polymerization. Generally speaking, the storage temperature should be maintained at 5 to 25 degrees Celsius, away from heat sources and direct sunlight, so as not to affect its stability due to excessive temperature.
Third, the storage place must be well ventilated. The substance may evaporate some harmful gases to the human body. Good ventilation can discharge these gases in time to prevent their accumulation in the air and reduce the harm to personnel and the environment. At the same time, the ventilated environment also helps to reduce the local temperature and ensure the safety of storage.
Fourth, during transportation, ensure that the packaging is intact. If the packaging is damaged, it will not only cause material leakage, pollute the environment, but also react with external substances, posing a safety hazard. The packaging material should have good sealing and corrosion resistance, which can effectively resist vibration, collision and friction during transportation.
Fifth, the means of transportation should be clean and dry, and no other chemicals should be retained to prevent chemical reactions with 2% 2C5 -bis (triethylamino) quinoline. And during transportation, relevant transportation regulations must be strictly observed to avoid long stays in high temperature periods or poor road conditions to ensure safe and smooth transportation.