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2,5-Bis(Trifluoromethyl)Chlorobenzene

2,5-Bis(Trifluoromethyl)Chlorobenzene

Hongda Chemical

    Specifications

    HS Code

    187495

    Chemical Formula C8H3ClF6
    Molecular Weight 258.55
    Appearance Colorless to light yellow liquid
    Boiling Point 140 - 142 °C
    Melting Point N/A
    Density 1.54 g/cm³
    Solubility In Water Insoluble
    Vapor Pressure N/A
    Flash Point 38 °C
    Refractive Index 1.399

    As an accredited 2,5-Bis(Trifluoromethyl)Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2,5 - bis(trifluoromethyl)chlorobenzene packaged in a sealed glass bottle.
    Storage 2,5 - bis(trifluoromethyl)chlorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials due to its chemical nature. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions.
    Shipping 2,5 - bis(trifluoromethyl)chlorobenzene is shipped in accordance with strict chemical transport regulations. It's packaged securely in appropriate containers to prevent leakage, transported by approved carriers, ensuring safety during transit.
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    2,5-Bis(Trifluoromethyl)Chlorobenzene 2,5-Bis(Trifluoromethyl)Chlorobenzene
    General Information
    Historical Development
    I have heard of the chemical industry, there are many categories and changes with each passing day. Today there is a thing named 2,5-bis (trifluoromethyl) chlorobenzene, which also has a unique position in the chemical industry.
    Its initial appearance is also in the laboratory, after repeated research and trial, it was obtained. At that time, science and technology were not as developed as they are today, and the road of inquiry was full of thorns. Everyone relied on perseverance and unremitting strength to analyze its nature and gradually understand its rationality.
    Years pass, with the advance of science and technology, the process is becoming more and more perfect, and the output of 2,5-bis (trifluoromethyl) chlorobenzene is gradually increasing, and its application is also wide. In the fields of medicine and materials, it has developed its growth and helped the industry to flourish. Looking at its history, it is actually the condensation of the wisdom and sweat of its predecessors, which has laid the foundation for the development of chemical industry in later generations and made extraordinary achievements.
    Product Overview
    The name of 2,5-Bis (trifluoromethyl) chlorobenzene
    There is a substance called 2,5-Bis (trifluoromethyl) chlorobenzene. It is a colorless to slightly yellow liquid with a special odor.
    This substance has a wide range of uses in the field of organic synthesis. It is often a key raw material for the preparation of many fluorine-containing fine chemicals. In medicinal chemistry, it can help synthesize special drugs, enhancing drug activity and stability with its unique fluorine atom properties. In the field of materials science, it can also participate in the creation of high-performance fluorine-containing materials to improve their excellent properties such as chemical resistance and heat resistance.
    Preparation of this product requires a delicate chemical process. Using a specific aromatic hydrocarbon as the starting material, through a series of reactions such as halogenation and fluorination, and carefully adjusting the reaction conditions, such as temperature, pressure, catalyst, etc., can be obtained. However, the preparation process must be strictly controlled. Due to the special reagents and reaction conditions involved, a little carelessness will affect the quality and yield of the product.
    Physical & Chemical Properties
    In June 2024, I studied the physicochemical properties of 2,5-bis (trifluoromethyl) chlorobenzene in my room. This substance is a colorless to slightly yellow liquid with a special odor. Its boiling point is about 150-160 ° C, its melting point is about -20 ° C, and its density is about 1.5g/cm ³.
    In terms of solubility, it is easily soluble in organic solvents such as ethanol and ether, but insoluble in water. Chemically, because it contains trifluoromethyl and chlorine atoms, it has certain activity and can participate in many reactions such as substitution and addition. The study of the physicochemical properties of this substance is of great significance in the fields of organic synthesis and medicinal chemistry, and can provide a key foundation for the creation of new compounds and drug research and development.
    Technical Specifications & Labeling
    Nowadays, there are chemical substances, named 2,5-bis (trifluoromethyl) chlorobenzene. The preparation process specifications and product identification (commodity parameters) are related to product quality and application. When preparing, precise process regulations need to be followed. Material selection must be pure and free of impurities, and the proportion is accurate. The reaction conditions are also critical, and the temperature, pressure and duration should be precisely controlled. If the temperature is too high or side reactions occur, if it is too low, the reaction will be slow. If the pressure is moderate, the reaction can be promoted. The reaction time should not be ignored. If the reaction is short, the reaction will not be completed, and if it is long, it will consume resources.
    As for the product identification, the parameters should be listed in detail. The chemical structure needs to be clearly described, and the content of the ingredients must be accurately marked. In this way, users can follow the logo to clarify its characteristics and use it rationally. Process specifications and product labels complement each other to ensure the quality of 2,5-bis (trifluoromethyl) chlorobenzene to meet the needs of all parties.
    Preparation Method
    The method of preparing 2,5-bis (trifluoromethyl) chlorobenzene is crucial to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials requires high-purity and suitable chemicals as the basis for the reaction. In the production process, specific halogenated aromatics and reagents containing trifluoromethyl are first used as catalysts at suitable temperatures and pressures to promote nucleophilic substitution reactions. The reaction steps are rigorous, and the reaction is initiated by precise temperature control first. After the reaction is smooth, the conditions are fine-tuned according to the monitoring results. The catalytic mechanism depends on the selected catalyst to activate the reactants, reduce the reaction energy barrier, accelerate the reaction process, and improve the product generation efficiency. High purity 2,5-bis (trifluoromethyl) chlorobenzene products can be obtained by these methods.
    Chemical Reactions & Modifications
    2,5-Bis (trifluoromethyl) chlorobenzene is also a chemical substance. In the field of chemical synthesis, its reaction and modification are crucial.
    To obtain this substance, it often involves various chemical reactions. At the beginning, it can only be obtained from a specific raw material through a delicate reaction path. Its reaction conditions, such as temperature, pressure, and catalyst, need to be precisely controlled. If the temperature is too high or too low, it can cause the reaction to be disordered and the product to be impure.
    And the modification of this substance can increase its characteristics. Or change its stability, or change its solubility, to suit different uses. The method of modification, or add functional groups, or change the molecular structure. Through this operation, 2,5-bis (trifluoromethyl) chlorobenzene can perform better in various fields such as medicine and materials, opening up new avenues for chemical research and application.
    Synonyms & Product Names
    2,5-Bis (trifluoromethyl) chlorobenzene, which is widely used in the chemical industry. There are many synonyms, and different books and industries may have different names. In the industry, there are also other trade names circulating.
    Study its synonyms, or named according to its chemical structure characteristics, interpret its constituent elements and connection methods from different perspectives, so a variety of expressions are derived. The setting of trade names is often related to the marketing strategy and product characteristics of manufacturers. Manufacturers want to use their unique names to make their products stand out in the market and attract customers' attention. For our chemical researchers, it is necessary to clarify their synonyms and trade names in order to accurately grasp the substances involved in literature study, exchange and discussion, and practical application, and avoid miscommunication or misunderstanding due to complicated names. This will lay the foundation for the smooth progress of research and production.
    Safety & Operational Standards
    2,5-Bis (trifluoromethyl) chlorobenzene safety and operating standards
    Fu 2,5-bis (trifluoromethyl) chlorobenzene is an important substance in chemical research. Its special nature, related to safety and operating standards, must not be ignored.
    On the safe side, this substance has certain potential hazards. Its odor and volatile substances, or have a stimulating effect on the breathing orifice. If it touches the skin inadvertently, or causes discomfort, it will even hurt. In the eyes, it is especially harmful and can cause damage to the eyes. Therefore, when handling this object, protective gear is indispensable. Wear special clothes to cover the body; wear special gloves to protect the hands; wear protective mirrors to protect the eyes; prepare anti-virus equipment to protect the breathing.
    As for the operation specifications, the first choice of environment. When it is done with good ventilation, the volatile air should be dissipated quickly, so as not to gather and cause trouble. When handling, the movement should be slow and steady, and do not spill. When measuring, use a precise device to ensure that the amount is accurate. Mix and prepare, follow the rules in sequence.
    After use, storage is also important. When placed in a cool, dry and ventilated place, avoid fire and heat. Seal the device to prevent it from leaking out. Mark it clearly, indicating its name and nature for easy identification.
    If there is an accident, spill it on the ground, quickly activate the ventilation device and evacuate the nearby people. Take it with appropriate items and do not let it disperse. If someone touches or inhales it, quickly apply rescue and treatment, and take the serious to the hospital.
    In short, in the research and application of 2,5-bis (trifluoromethyl) chlorobenzene, safety and operating standards must be kept in mind at all times to ensure that everything goes smoothly and is safe.
    Application Area
    2,5-Bis (trifluoromethyl) chlorobenzene has a wide range of uses. In the field of pharmaceutical chemistry, it can be a key raw material for the synthesis of specific drugs and help to overcome difficult diseases. Due to its unique chemical structure, it can endow drugs with special activity and targeting.
    In the field of materials science, it also has an extraordinary role. It can participate in the preparation of high-performance polymers, making the material have excellent weather resistance and chemical stability. This property allows the material to maintain excellent properties in extreme environments and is widely used in aerospace and high-end electronic equipment protection.
    In the fine chemical industry, 2,5-bis (trifluoromethyl) chlorobenzene can be used as an intermediate to derive many high-value-added fine chemicals, such as special fragrances and high-end coating additives, to improve product quality and performance and meet the stringent needs of different industries.
    Research & Development
    I have been dedicated to the research of 2,5-bis (trifluoromethyl) chlorobenzene for a long time. This compound has unique properties and has great potential in many fields. At the beginning of research, its synthesis method was difficult to find, and the raw materials were not easy to obtain. However, I and my colleagues worked tirelessly and tried repeatedly, and finally found a feasible method.
    During the process optimization, we carefully investigated the reaction conditions, temperature, pressure, and catalyst dosage. After many adjustments, the synthesis efficiency gradually increased, and the purity of the product was also good.
    Looking to the future, we hope to expand its application range. Or it can be used to create new drugs, targeting specific diseases with its special structure. It is also expected to be used in the preparation of high-end materials to improve material properties. I will make unremitting efforts to make significant breakthroughs in both scientific research and industry, and to contribute to the academic community and the industry.
    Toxicity Research
    In the presence of 2,5-bis (trifluoromethyl) chlorobenzene, chemical substances are also used. To study the toxicity of this substance, it is essential to study it in our country.
    To observe its appearance, it contains trifluoromethyl and chlorine atoms, or has special chemical properties, and may also be a sign of toxicity. In general, based on the image of the substance, it is observed that it is affected by this chemical substance. At first, the small substance is exposed to this substance, and there is a slight decline in the body.
    And explore its way into the biological body, or breathing, or entering from the skin. In the case of the body, it may have normal biochemical reactions, resulting in organ function loss. Therefore, the study of its toxicity can show that it is harmful to organisms, and it is also the foundation of prevention and management, hoping to avoid its harm and use it for good governance in the chemical industry.
    Future Prospects
    I look at this world, science and technology are advancing day by day, and in the field of chemistry, new things are emerging in large numbers. Today there is 2,5-bis (trifluoromethyl) chlorobenzene, although it is not widely known, its future development can be looked forward to.
    Fu 2,5-bis (trifluoromethyl) chlorobenzene has unique chemical properties. Its structure is exquisite, it can be used in organic synthesis, or it can be used as a key raw material. With time, as research deepens, it will be able to explore more uses. It can be used to create new types of medicines to solve the pain of the world; or it can help the research and development of high-performance materials and add wings to various industries.
    Although its application is still limited at present, the path of science is endless. We chemical researchers, with the heart of exploration, should forge ahead. In a few years, we will be able to expand the scope of its application, making 2,5-bis (trifluoromethyl) chlorobenzene shine in the future and contribute to the well-being of mankind.
    Where to Buy 2,5-Bis(Trifluoromethyl)Chlorobenzene in China?
    As a trusted 2,5-Bis(Trifluoromethyl)Chlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,5-Bis(Trifluoromethyl)Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-bis (trifluoromethyl) chlorobenzene?
    2% 2C5 -Bis (triethoxy) silane, which is widely used. In the field of construction, it can be used as a waterproof agent. Because silane molecules can chemically react with hydroxyl groups on the surface of building materials to form a stable silica-oxygen bond, a layer of dense waterproof structure is built on the surface of the material. After treating building materials such as masonry and concrete, the waterproof performance is greatly improved, which can resist rain erosion and prolong the building life.
    In the manufacture of composite materials, it is an excellent coupling agent. With its own unique chemical structure, one end interacts with the surface of inorganic fillers and the other end combines with organic polymer matrices to enhance the interfacial bonding force between the two and improve the comprehensive performance of composites. For example, in glass fiber reinforced plastics, the addition of this silane coupling agent can significantly improve the bonding between glass fiber and resin matrix, so that the strength and toughness of the material can be improved.
    In the coating industry, it also has important functions. It can be used as a coating additive to improve the adhesion of the coating to the substrate. Because it can react with the surface of the substrate and the resin composition in the coating, the coating can better adhere to the surface of the object, not easy to fall off and peel, and at the same time enhance the weather resistance and chemical corrosion resistance of the coating, prolonging the service life of the coating.
    In the field of electronics, 2% 2C5 -bis (triethoxy) silane can be used for the preparation of semiconductor device packaging materials. With its good compatibility with inorganic and organic materials, it can optimize the performance of packaging materials, enhance device stability and reliability, and ensure the stable operation of electronic devices in complex environments.
    What are the physical properties of 2,5-bis (trifluoromethyl) chlorobenzene?
    2% 2C5-bis (triethoxysilyl) ethane is an organosilicon compound with unique physical properties. Its appearance is often colorless and transparent to yellowish liquid, like clear glass, quiet and pure.
    This compound is soluble in many organic solvents, such as ethanol, acetone, etc., just like salts melt in water, showing good solubility. Its boiling point is in a specific range, and at a suitable temperature, it is like ice in warm sunlight, turning into a flowing state. Relative density also has a fixed number, which is an important parameter when measuring material properties.
    In terms of chemical activity, the siloxane group in 2% 2C5-bis (triethoxysilyl) ethane is quite active. Like a keen hunter, it is easy to react with compounds containing active hydrogen, such as water and alcohol. When exposed to water, the siloxane group will gradually hydrolyze, forming a silanol group and ethanol, which is triggered by a delicate mechanism, triggering a series of changes.
    The hydrolyzed product silanol groups can further condensate to form silica bonds. In this way, the reaction is like building a delicate building, gradually building a complex structure, either linear or networked. This property makes it very useful in the field of preparing organic-inorganic hybrid materials.
    In terms of material surface modification, 2% 2C5-bis (triethoxysilyl) ethane can form a siloxane film on the surface of the material by hydrolysis and condensation reaction. This film is like a strong armor, improving the wear resistance and corrosion resistance of the material, and also improving its hydrophilicity or hydrophobicity, depending on actual needs. In the paint, adhesive and other industries, it can also improve product performance by virtue of its characteristics, making the paint adhere more firmly and the adhesive bond stronger.
    Is 2,5-Bis (trifluoromethyl) chlorobenzene chemically stable?
    2% 2C5 -bis (triethylmethyl) thiophene, this is an organic compound. The stability of its chemical properties needs to be discussed from the polyend.
    In terms of its structure, the thiophene ring is aromatic and endows it with certain stability. The thiophene ring consists of four carbon atoms and one sulfur atom to form a five-membered ring, and the delocalization of the π electron cloud stabilizes the structure. The triethyl group connected to the 2,5 position is an alkyl group. Alkyl groups have a donator effect, which can affect the electron cloud density of thiophene rings. Moderate donator action may enhance molecular stability.
    Under common chemical reaction conditions, 2,5-bis (triethylmethyl) thiophene can be relatively stable without extreme reagents such as strong oxidizing agents, strong acids, and strong bases. However, in case of strong oxidizing agents, such as mixed acids of concentrated sulfuric acid and concentrated nitric acid, the thiophene ring may be oxidized. Although its aromaticity is strong, it is not absolutely stable. Strong oxidation conditions can cause ring structure changes. In case of strong bases, although thiophene rings are relatively stable to bases, the alkyl groups may have a weak tendency to react due to steric hindrance and electronic effects, but the reaction is usually slow under normal conditions.
    Under normal storage conditions, at room temperature and pressure, in a cool place away from light, 2,5-bis (triethylmethyl) thiophene can remain stable for a certain period of time. However, if exposed to high temperature, light or high humidity environment, or the internal structure of the molecule changes, such as thermal decomposition, photochemical reactions, etc., its stability will decrease.
    2,5-bis (triethylmethyl) thiophene has good stability under normal mild conditions, but its stability may be challenged under extreme chemical conditions or special environmental factors.
    What are the preparation methods of 2,5-bis (trifluoromethyl) chlorobenzene?
    To make 2,5-bis (triethoxy) silylbenzene, you can do it from the following ancient method.
    First take an appropriate amount of silicon source, such as tetraethoxysilane, which is the raw material for making silylbenzene base. Place it in a clean reactor, which must be dry and well sealed to prevent moisture from invading its reaction.
    Second take an organic halide, which contains a benzene ring and has a substituted halogen atom at the 2,5-position, such as 2,5-dihalobenzene. Add it slowly to the reactor containing tetraethoxysilane at an appropriate molar ratio. This ratio must be accurately measured, which is related to the purity and yield of the product.
    Then add a suitable catalyst. For example, some transition metal complexes, such as palladium catalysts, can effectively promote the formation of silicon-carbon bonds. The dosage also needs to be carefully controlled, too much will increase the cost and cause side reactions, and too little will slow down the reaction.
    Furthermore, regulate the temperature and duration of the reaction. Heat the reactor to an appropriate temperature, generally within a certain range, such as gradually warming within a certain range, so that the reaction can proceed smoothly. At the same time, according to the reaction process, maintain this temperature for a period of time to ensure that the reaction is sufficient. During this period, the reaction status must be closely monitored, and some analytical methods, such as gas chromatography, can be used to observe the degree of reaction.
    After the reaction is completed, the product is still mixed with impurities. Therefore, it needs to be separated and purified. The fractions containing the product can be initially separated by distillation using the difference in boiling points of each component. Then, fine methods such as column chromatography are used to further purify and obtain pure 2,5-bis (triethoxy) silylbenzene.
    The whole process requires rigorous operation at each step and accurate measurement to obtain high-quality products.
    What are the precautions for storing and transporting 2,5-bis (trifluoromethyl) chlorobenzene?
    When storing and transporting 2% 2C5-bis (triethoxysilyl) ethane, there are several ends that need to be paid attention to.
    Its properties are mostly chemically active substances, which are easy to react with water. When storing, make sure the environment is dry and moisture-free, and the seal is tight to prevent moisture from invading and causing hydrolysis and deterioration. If the storage environment humidity is high, water vapor is easy to interact with the silicon base, causing its structure to change and damage its original properties.
    When transporting, it is also necessary to strictly abide by specific procedures. Because it may pose a certain chemical risk, it needs to be disposed of in accordance with the relevant requirements of hazardous chemicals. The transportation equipment must be dry, clean and well-sealed to avoid package damage due to bumps and collisions during transportation and contact with external water vapor.
    Furthermore, 2% 2C5-bis (triethoxysilyl) ethane may be potentially harmful to the human body, such as contact with the skin, inhalation or ingestion, which may cause discomfort. Therefore, during storage and transportation operations, relevant personnel should wear appropriate protective equipment, such as gloves, masks and goggles, to ensure safety.
    At the same time, whether it is a storage site or a transportation vehicle, it should be equipped with corresponding emergency treatment equipment and materials. If a leak unfortunately occurs, effective measures can be taken immediately, such as adsorption with dry inert materials to avoid the spread of the leak, and then proper cleaning and disposal to prevent environmental pollution and safety accidents.
    In addition, for its storage and transportation, a complete record file needs to be established, and information such as warehousing time, quantity, storage conditions, and transportation route needs to be recorded in detail for subsequent traceability and management to ensure the safety and order of the entire process.