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2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride

2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    885306

    Chemical Formula C8H3ClF6O2S
    Molecular Weight 322.61
    Appearance Typically a solid
    Color May be colorless to pale - colored
    Pungency Has a pungent odor
    Reactivity Reactive towards nucleophiles due to the presence of sulfonyl chloride group
    Solubility Soluble in common organic solvents like dichloromethane, chloroform
    Melting Point Specific value would depend on purity, but generally in a certain range
    Boiling Point Determined by its molecular structure and intermolecular forces
    Hazard Corrosive, can cause skin and eye damage

    As an accredited 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2,5 - bis(trifluoromethyl)benzenesulfonyl chloride in a sealed chemical - grade bottle.
    Storage 2,5 - bis(trifluoromethyl)benzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. It must be kept away from heat, flames, and moisture as it is reactive. Store it in a tightly - sealed container, preferably in a corrosion - resistant material, to prevent leakage and reaction with the environment. Avoid storing near incompatible substances like bases, reducing agents, and water - containing materials.
    Shipping 2,5 - bis(trifluoromethyl)benzenesulfonyl chloride is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations, ensuring leak - proof containers to prevent spills during transit.
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    2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride
    General Information
    Historical Development
    "Memorizing the Development of 25bis (Trifluoromethyl) Benzenesulfonyl Chloride"
    Taste the chemical industry, there are many categories, and new products have emerged. 25bis (trifluoromethyl) benzenesulfonyl chloride is also a special product in various chemical products.
    At the beginning, the academic community has no knowledge, and the researchers are rare. However, with the advance of science and technology, people are gradually looking at its use. At the beginning, the preparation method is still simple, the yield is not high, and the quality is not enough.
    After that, Zhu Xian made every effort to improve the production method. Optimize the process, select raw materials, the yield is rising, and the quality is also excellent. In the field of organic synthesis, it gradually shows its ability, adds a new path to various reactions, and helps the chemical industry to thrive. From this perspective, this product has self-concealed and shines, thanks to the research of scholars and the diligent work of craftsmen, it is possible to add this brilliant chapter to the history of chemical industry.
    Product Overview
    2,5-Bis (trifluoromethyl) benzenesulfonyl chloride is a key material for our research in chemical products. What is its shape? Looking at it, it is a colorless to light yellow liquid, shiny in sunlight, and has a pungent smell, which makes people frown.
    In terms of its properties, this product has a very high activity, and reacts violently in contact with water, releasing hydrogen chloride gas, which is like a dragon getting water and overturning the river. Its reactivity is in the field of organic synthesis, like a sharp blade, which can break all kinds of chemical bonds and build novel molecular structures.
    It has a wide range of uses and is often the cornerstone of the preparation of special functional materials. It has traces in medical chemistry and materials science. It can help medicine synthesize delicate structures to treat various diseases; in the field of materials, it can give materials unique properties, such as corrosion resistance and heat resistance.
    Use it with caution, because it is highly corrosive and toxic. If you accidentally touch it, your skin will be burned and your organs will also be damaged. Therefore, when operating, you must follow strict procedures, use protective equipment, and do it in a well-ventilated place to ensure safety.
    Physical & Chemical Properties
    In 2023, our company will focus on the research of 2,5-bis (trifluoromethyl) benzenesulfonyl chloride. This compound has a light yellow color, a flowing liquid at room temperature, and a specific smell. Its melting point is about -10 ° C, and its boiling point is about 240 ° C. It dissolves well in organic solvents such as dichloromethane and chloroform.
    In terms of chemical activity, 2,5-bis (trifluoromethyl) benzenesulfonyl chloride is extremely active. The sulfonyl chloride group has unique properties and is easy to react with alcohols and amines to form corresponding sulfonates and sulfonamides. This reaction property is widely used in the field of organic synthesis and can prepare a variety of fluorinated organic compounds. Because it contains trifluoromethyl, the synthesized products have good lipophilicity and stability, and have great potential in the creation of medicine and pesticides. In-depth exploration of its physical and chemical properties will help to expand its application in the field of fine chemicals and contribute to the creation of new compounds.
    Technical Specifications & Labeling
    Today there is a product called "2,5-Bis (trifluoromethyl) benzenesulfonyl chloride". In the field of my chemical research, its technical specifications and identification (commodity parameters) are the key.
    Regarding its technical specifications, it is necessary to ensure that the purity is excellent and there are few impurities, which is the foundation of its chemical reaction effect. During preparation, all conditions must be precisely controlled, such as temperature, pressure, proportion of reactants, etc. A slight difference will affect the quality.
    As for the label (commodity parameters), its physical and chemical characteristics, such as melting point, boiling point, solubility, etc., should be detailed so that the user can see it at a glance. On the package, it should also be clearly marked to clarify its characteristics and precautions for use. In this way, this chemical can be used in scientific research and production to achieve its due effect, without the effort of research and preparation.
    Preparation Method
    The method of making 2,5-bis (trifluoromethyl) benzenesulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take an appropriate amount of benzene raw materials containing trifluoromethyl, and put them into the reactor according to a specific ratio. With a specific catalyst, control the temperature and pressure in the precise range. At the beginning, the temperature is raised to about [X] ° C, and the raw materials are slowly blended to catalyze the reaction. After several hours, the reaction gradually stabilizes. Then, the temperature and pressure are fine-tuned in sequence, and auxiliary reagents are added in time according to the reaction process to promote the reaction to move towards the formation of the target product. After the reaction is completed, after separation and purification, pure 2,5-bis (trifluoromethyl) benzenesulfonyl chloride is obtained. This preparation method is carefully considered in the selection of raw materials, the control of reaction conditions, and the application of catalysis, in order to achieve high efficiency and high quality.
    Chemical Reactions & Modifications
    F 2,5-Bis (trifluoromethyl) benzenesulfonyl chloride is also a chemical product. In the chemical reaction and chemical properties, there are places to be investigated.
    Its chemical reaction often uses the properties of sulfonyl chloride to interact with various reagents. In case of nucleophiles, chlorine is easy to replace it with a nucleophilic group and form a new compound, which should be used in the process of chemical synthesis, which is quite useful.
    As for chemical properties, it has trifluoromethyl, which is active and has strong electron-absorbing properties. This makes the product have a special tendency in chemical reactions, which can help the selection and effect of the reaction. And because it contains sulfonyl chloride groups, it can participate in various reactions and expand the scope of its use.
    If you want to make good use of it, you must deeply understand its transformation and transformation. Only by studying the rules of response in detail and observing the changes in its nature can you do your best in the field of transformation and get good results.
    Synonyms & Product Names
    2,5-Bis (trifluoromethyl) benzenesulfonyl chloride is another name and trade name in the field of chemical industry, and is also valued by researchers. Its nicknames often change due to regions and habits, or there are "difluorobenzenesulfonyl chloride" and the like, but they all refer to this thing. The trade names are circulated in the market, such as "excellent fluorosulfonyl agent", etc. Although the names are different, the quality is the same. This chemical has unique properties, which is for researchers to explore its properties and uses. In the reaction, it shows specific energy, either as a new product or as a catalyst, to help the progress of chemical industry. Researchers use it as the key to open the door to the unknown, explore the subtlety of chemistry, and hope to develop its advantages in use, add new colors to the industry, promote the prosperity of chemical industry, and lead to the advancement of science and technology.
    Safety & Operational Standards
    Specifications for safety and operation of 2,5-Bis (trifluoromethyl) benzenesulfonyl chloride
    Fu 2,5-Bis (trifluoromethyl) benzenesulfonyl chloride is a chemical commonly used in chemical research. In experimental operation, safety and standardization are of paramount importance.
    This chemical is dangerous to some extent. It is corrosive and can cause burns when it touches the skin. If it is not carefully entered into the eyes, it is especially harmful. It is necessary to rinse with plenty of water immediately and seek medical attention immediately. Therefore, when operating, protective equipment is indispensable. It is advisable to wear protective clothing, protective gloves and goggles to prevent accidents.
    Furthermore, it is easy to react in the air or in contact with water. When storing, be sure to keep it in a dry, cool and well-ventilated place, away from fire sources and oxidants. When taking it, the operation should be carried out in the fume hood to prevent the escape of harmful gases and endanger people.
    During operation, precise control of dosage is also a priority. When weighing, use precise instruments, and the action should be stable to avoid spilling. When reacting, strictly follow the established procedures and conditions, and pay close attention to the reaction process, such as changes in temperature and pressure, to prevent accidents.
    After the experiment is completed, the remaining 2,5-bis (trifluoromethyl) benzenesulfonyl chloride cannot be discarded at will, and should be properly disposed of according to regulations. The utensils used should also be cleaned in time to remove residues to prevent corrosion and cross-contamination.
    In short, when handling this chemical, safety must be the priority and operating standards must be strictly adhered to in order to ensure the smooth operation of the experiment and the safety of personnel.
    Application Area
    2,5-Bis (trifluoromethyl) benzenesulfonyl chloride is also a good chemical product. Its application field is quite extensive. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create special drugs, cure various diseases, and save patients from pain. In the field of material science, it can optimize material properties, make it more stable and functional, and meet diverse needs. In the field of fine chemicals, it is an important role in the preparation of high-end fine chemicals, improving product quality and added value. The use of natural materials is indeed not to be underestimated, and it is brilliant in many fields, contributing to scientific and technological progress and industrial development.
    Research & Development
    Today there is a product called 2,5-bis (trifluoromethyl) benzenesulfonyl chloride. I am a chemical researcher to explore and develop it. This product has unique properties and is often a key reagent in the field of organic synthesis.
    In the past, it was still shallow to explore, but today it is different. After repeated tests, its reaction mechanism was observed and its applicable scenarios were clarified. In catalytic reactions, it exhibits extraordinary activity and can make many reactions advance efficiently.
    Looking to the future, I hope to be able to tap its potential in the way of green synthesis. It may be possible to optimize the process, reduce energy consumption, reduce pollution, and promote its wide application. Therefore, 2,5-Bis (trifluoromethyl) benzenesulfonyl chloride will thrive in the field of chemistry and promote the progress and development of the industry.
    Toxicity Research
    Since modern times, the chemical refinement, all kinds of new substances are frequent, 2,5-bis (trifluoromethyl) benzenesulfonyl chloride this compound, also into our research field. I have been focusing on its toxicity research for a long time.
    After various experiments, this compound can show a certain toxicity under specific conditions. It may interact with molecules in organisms, disturbing their normal physiological order. If combined with key substances such as proteins and nucleic acids, cell function is damaged.
    The appearance of toxicity is also restricted by many factors. Such as the size of the dose, the duration of action, and the difference between individual organisms. Small doses are used for a short time, or only cause slight discomfort; large doses are used for a long time, and serious diseases are feared.
    We should investigate in depth to clarify its toxic mechanism, provide evidence for protection and application, and avoid its harm and promote its benefits, so as to promote chemical substances, which are beneficial to the world and not a disaster.
    Future Prospects
    The future prospect concerns the 2,5-bis (trifluoromethyl) benzenesulfonyl chloride. I look at this compound, its unique nature, the field of application, the potential is infinite. In the process of organic synthesis, it may be a key reagent to help form exquisite structures. In the way of material creation, it is also expected to give specific properties to materials and open up new horizons. Although the current understanding is not complete, with time and advanced scientific research, we will be able to understand more of its profound meaning. At that time, it may be used in the end of high-tech, such as electronic devices, to make its efficiency leap; or it can be used in the field of medical research and development, to generate special drugs and benefit all living beings. This is my vision for its future, hoping to come true, to be used by the world, and to add luster and glory.
    Where to Buy 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride in China?
    As a trusted 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    2% 2C5-bis (triethylamino) benzoxazoloborane, its main uses are as follows:
    This compound plays a crucial role in the field of organic synthesis. In many catalytic reactions, it often acts as a highly efficient catalyst. For example, in asymmetric reduction reactions, it exhibits excellent catalytic performance, which can selectively promote the reduction and transformation of substrates to generate products of specific configurations. This property makes it significant in drug synthesis. Drug molecules often have strict requirements for three-dimensional configurations. With the help of 2% 2C5-bis (triethylamino) benzoxazoloborane as a catalyst, it can precisely synthesize pharmaceutical active ingredients with specific configurations, greatly improving the efficiency and success rate of drug development.
    In the preparation of some functional materials, the use of this compound can regulate the reaction process and product structure, so as to obtain materials with unique properties, such as some materials with special optical and electrical properties. Through fine control of reaction conditions and the rational use of 2% 2C5 -bis (triethylamino) benzoxazole borane, materials that meet specific needs can be prepared to meet the application requirements of different fields.
    In chemical research, as an important reagent, it provides a powerful tool for researchers to explore new reaction pathways and expand organic synthesis methodologies. With its unique chemical properties, researchers can conduct innovative reaction research and promote the continuous development of organic chemistry.
    What are the physical properties of 2,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    2% 2C5 -Bis (triethylamino) benzothiazole buzz salt, this material is complex and delicate, and listen to me carefully.
    Looking at its shape, under normal circumstances or fine powder, pure color, light weight like a feather, delicate feeling like quicksand slipping through the fingers, this is its external shape.
    As for its solubility, it can show unique properties in many organic solvents. When encountering polar organic solvents, such as alcohols, it is like ice melting in water, quietly melting, uniformly dispersing, forming a clear and translucent liquid, like a mirror without waves; in non-polar solvents, it is like oil droplets entering water, repelling each other, difficult to integrate, and clear boundaries.
    When it comes to stability, in a conventional temperature and humidity environment, it is like a deep mountain pine, stable as a rock, and can maintain its structure and properties unchanged for a long time. In case of extreme conditions, the high temperature is scorching like the hot summer sun, or the strong acid and alkali erosion is like a violent wind and rain, its structure will be like a dangerous building, prone to change, and its chemical properties will change accordingly.
    Furthermore, its optical properties are particularly peculiar. When illuminated by specific wavelengths of light, it is as if the stars are lit at night, and it can emit brilliant fluorescence. The color of the light changes subtly with the surrounding environment, or it is as gorgeous as the flowers in spring, or as blue as the cold pool in autumn, which is breathtaking. This property makes it useful in many fields, such as fluorescent markers, which are like a guide in the dark night, illuminating the direction of scientific research and exploration; in optical materials, it is also like the pen of a skilled craftsman, drawing a wonderful optical picture.
    2% 2C5 -Bis (triethylamino) benzothiazole buzz salt has unique physical properties. It is a rare treasure in scientific research and industry, with endless potential to be discovered by our generation.
    What is the synthesis method of 2,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    The synthesis of 2% 2C5-bis (triethoxysilyl) benzoxazine is an important research in the field of organic synthesis. The synthesis steps are complicated and delicate, and specific procedures and conditions must be followed to obtain the ideal product.
    To synthesize this compound, the first raw material selection and preparation. An appropriate amount of 2,5-dihydroxybenzaldehyde, triethoxysilane and other necessary reagents should be prepared. The purity and quality of these raw materials have a profound impact on the success or failure of the synthesis, so careful selection must be made to ensure that there are no impurities.
    In the initial stage of synthesis, 2,5-dihydroxybenzaldehyde is often dissolved in a suitable solvent to make it evenly dispersed. The choice of solvent is related to the rate and effect of the reaction. Generally, inert organic solvents such as absolute ethanol and toluene are selected, which can dissolve the raw materials well without interfering with the reactants.
    Then, under stirring, slowly add triethoxysilane. This process requires strict temperature control, usually maintained in a moderate temperature range, such as 60-80 degrees Celsius. If the temperature is too high or too low, the reaction may be out of control or the rate is too slow, affecting the formation of the product. The stirring rate also needs to be moderate to ensure that the reactants are fully contacted and promote the reaction.
    To make the reaction more complete, a specific catalyst is often added. The catalyst can effectively reduce the activation energy of the reaction and accelerate the reaction process. Organic base catalysts, such as triethylamine, can be added in a certain proportion to precisely control the rate and direction of the reaction.
    When the reaction is going on, it is necessary to use monitoring means, such as thin layer chromatography (TLC) or nuclear magnetic resonance (NMR) technology, to understand the reaction process in real time. When the reaction reaches the expected level, that is, the conversion rate of raw materials reaches a high level, and the purity and structure of the product meet the expectations, the reaction should be stopped in time.
    After the reaction is terminated, a series of separation and purification steps are required. The solvent is first removed by distillation, and then the product is further purified by means of column chromatography or recrystallization to remove unreacted raw materials, by-products and impurities to obtain high-purity 2,5-bis (triethoxysilyl) benzoxazine.
    Synthesis of 2% 2C5-bis (triethoxysilyl) benzoxazine requires careful control of raw materials, reaction conditions, catalysts and post-processing to achieve efficient and high-quality synthesis.
    What are the precautions for storing and transporting 2,5-bis (trifluoromethyl) benzenesulfonyl chloride?
    2% 2C5 - Bis (triethoxysilyl) sodium benzenesulfonate is a commonly used auxiliary agent in fine chemicals. When storing and transporting, many matters should be paid attention to, as follows:
    - ** Storage **:
    - ** Environment drying **: This material is very easy to absorb moisture. If the storage environment is humid, it will change its properties due to moisture absorption, and even agglomeration will occur, which will seriously affect the subsequent use effect. Therefore, it should be stored in a dry place, and the humidity of the warehouse should be controlled at 40% - 60%.
    - ** Temperature suitable **: Excessive temperature may cause its thermal decomposition, and too low temperature may cause its crystallization to precipitate. Generally speaking, the storage temperature is 5 ° C - 35 ° C, and it is necessary to avoid direct sunlight and heat sources.
    - ** Isolated storage **: Do not store with oxidants, acids, and alkalis. Due to its active chemical nature, contact with oxidants can easily trigger oxidation reactions, and contact with acids and bases may cause neutralization or other chemical reactions, resulting in deterioration.
    - ** Packaging seal **: Be sure to ensure that the packaging is intact and tightly sealed to prevent air and moisture from invading. After taking it, the packaging should be sealed in time to prevent the material from being exposed to air for a long time.
    - ** Transportation **:
    - ** Packaging Stable **: Appropriate packaging materials should be selected before transportation, such as iron drums or plastic drums lined with plastic bags, to ensure that the packaging does not break or leak during the transportation turbulence.
    - ** Prevent Collision **: During transportation, it should be lightly loaded and unloaded to avoid severe collisions and vibrations and prevent packaging damage. At the same time, it needs to be transported separately from other chemicals to prevent mutual contamination.
    - ** Follow regulations **: To transport such chemicals, it is necessary to strictly follow the relevant national and local regulations on the transportation of hazardous chemicals. The transportation personnel need to have professional knowledge and operation skills, and the transportation vehicles should also post corresponding warning signs.
    What are the safety risks during the use of 2,5-bis (trifluoromethyl) benzenesulfonyl chloride and how to prevent them?
    2% 2C5 -Bis (triethoxysilyl) benzothiazole During use, there are the following safety risks and preventive measures:
    Toxicity risk
    This substance or its decomposition products may have certain toxicity and cause damage to the human body. If inhaled inadvertently, it may irritate the respiratory tract, causing symptoms such as cough and asthma; if exposed to the skin, it may cause skin allergies, redness, swelling, and itching; ingestion may harm the digestive system.
    The precautionary method is to ensure good ventilation in the use field, and to be equipped with effective ventilation equipment, such as exhaust fans, to disperse possible harmful gases. Users must wear appropriate protective equipment, such as gas masks, protective gloves, protective glasses, and protective clothing. After the operation is completed, clean the contact parts with water and soap in time.
    Risk of fire and explosion
    The substance or its vapor may be flammable or even explosive under specific conditions.
    When taking precautions, keep away from open flames, hot topics and strong oxidants. Fireworks should be strictly prohibited in the place of use, and electrical equipment should be explosion-proof. At the same time, it should be properly stored in a cool, dry and well-ventilated place, avoid direct sunlight, and store separately from other flammable and explosive items. In addition, it should also be equipped with suitable fire extinguishing equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc. Relevant personnel need to be familiar with their use methods.
    Environmental Risks
    If the substance leaks into the environment, it may cause pollution to soil, water bodies, etc.
    The key point of prevention is that the storage area needs to take anti-leakage measures, such as setting up cofferdams. In the event of leakage, emergency measures should be taken immediately, such as absorbing with inert materials such as sand and vermiculite, and then properly dispose of the collected materials to prevent them from entering the environment. Strengthen the management of the use process to avoid unnecessary emissions and protect the surrounding ecological environment.