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2,4-Dimethoxy-3-Fluoronitrobenzene

2,4-Dimethoxy-3-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

415934

Chemical Formula C8H8FNO4
Appearance Solid (usually)
Solubility In Water Low (expected, due to non - polar nature)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low (expected for a solid at ambient conditions)
Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

As an accredited 2,4-Dimethoxy-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,4 - dimethoxy - 3 - fluoronitrobenzene packaged in air - tight glass bottles.
Storage 2,4 - dimethoxy - 3 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent moisture and air exposure. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions, ensuring safe long - term storage.
Shipping 2,4 - dimethoxy - 3 - fluoronitrobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to ensure compliance with hazardous chemical shipping regulations. It's transported under controlled conditions to prevent any potential reactions.
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2,4-Dimethoxy-3-Fluoronitrobenzene 2,4-Dimethoxy-3-Fluoronitrobenzene
General Information
Historical Development
Regarding the historical development of 2,4-dimethoxy-3-fluoronitrobenzene
In the past, the field of chemistry was not as prosperous as it is today, and the art of organic synthesis was gradually explored. 2,4-dimethoxy-3-fluoronitrobenzene This compound was rarely known at the beginning.
At that time, chemists focused on the research of common substances, and the exploration of complex structures containing fluorine and nitro groups with methoxy groups was still shallow. Later, with the improvement of instruments, the theory was complete, and the methods of organic synthesis were becoming more and more abundant.
Scholars' attention gradually focused on this unique structure, because of its potential use in medicinal chemistry, materials science, etc. At first, it was tried to be prepared by a simple method, but the yield was quite low and there were many impurities. However, many people made unremitting efforts to improve the reaction conditions and find a suitable catalyst. After several years, a better synthesis path was obtained. The development of this compound is like a long road.
Product Overview
There is now a compound called 2,4-dimethoxy-3-fluoronitrobenzene. This compound has a unique structure. In its molecule, fluorine atoms are cleverly connected to nitro and dimethoxy groups.
Looking at its physical properties, it may show a specific color state at room temperature or have a unique odor, which remains to be seen in detail. Regarding its chemical properties, due to the electronegativity of fluorine, the strong electron absorption of nitro groups, and the electron-donating effect of dimethoxy groups, it has a unique activity in chemical reactions.
In the field of organic synthesis, this compound may be a key intermediary. Various functional groups can be introduced through specific reaction paths to build more complex organic molecules. It has potential applications in various fields such as medicine and materials, providing many possibilities for researchers to explore new substances and explore new uses.
Physical & Chemical Properties
2,4-Dimethoxy-3-fluoronitrobenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its shape, at room temperature, it may be a crystalline body, with a color or nearly pure white, with a specific crystal structure. Its melting point and boiling point are also fixed. The melting point is about XX degrees Celsius, and the boiling point is about XX degrees Celsius, which is related to the strength of its intermolecular forces.
In terms of its chemistry, its activity is unique because of its fluorine, nitro and methoxy groups. Nitro has strong electron-absorbing properties, which reduces the density of the electron cloud of the benzene ring, and is easy to lead to nucleophilic substitution. Although methoxy is the power supplier, its position also affects the molecular reactivity. The introduction of fluorine atoms, due to high electronegativity, changes the polarity and reaction check point of compounds, and shows specificity in many organic synthesis processes, which is important in the chemical industry and scientific research fields.
Technical Specifications & Labeling
2,4-Dimethoxy-3-fluoronitrobenzene is also a chemical product. Its process specifications and identification (commodity parameters) are related to the preparation and screening.
To make this product, the choice of raw materials and the precise ratio are the basis. The temperature and time control of the reaction need to be appropriate. In ancient theory, when in a kettle, put the materials in a certain order, observe their changes, and adjust them in a timely manner.
In terms of identification, the appearance color and crystal shape need to be clear. The standard of purity is related to quality. Parameters such as melting point and boiling point are also the basis for screening. And on the packaging, its name, nature and danger must be clearly stated to comply with the regulations. In this way, good products can be obtained and used in industry and scientific research.
Preparation Method
The method of making 2,4-dimethoxy-3-fluoronitrobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. First, take an appropriate amount of fluorobenzene, use concentrated nitric acid and concentrated sulfuric acid as mixed acids, control the temperature in a specific range, and carry out a nitrification reaction to obtain 3-fluoronitrobenzene. This step requires careful observation of the ratio of temperature to acid to prevent side reactions.
Then, take 3-fluoronitrobenzene as material and react with dimethyl sulfate under alkali catalysis. Potassium carbonate should be selected as the base, and acetone in the solvent can increase the reaction efficiency. Warm up to a certain temperature and maintain a certain time to make the etherification reaction sufficient. Pure 2,4-dimethoxy-3-fluoronitrobenzene is obtained by extraction, distillation, recrystallization and other purification methods. The whole process needs to strictly observe the conditions of each step to achieve high yield and purity.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 2,4-dimethoxy-3-fluoronitrobenzene. In chemical research, its reaction and modification are the gist of our research.
Looking at the reaction of this compound, its characteristics are affected by many factors. For example, the temperature and pressure of the reaction conditions, and the properties of the medium can all make the reaction path different from the product. To get the best effect, you must carefully adjust the conditions and observe its subtle changes.
As for the modification, it is designed to expand its use and increase its properties. Or adjust its molecular structure, add or subtract groups to give new energy. You can use the wonderful method of chemical synthesis and apply it carefully, hoping to obtain new substances with excellent properties.
The beauty of chemistry lies in the change of reaction and the wonder of modification. To study this 2,4-dimethoxy-3-fluoronitrobenzene, we must explore its endless secrets with scientific method and rigorous heart, and hope to contribute to the progress of chemistry.
Synonyms & Product Names
2,4-Dimethoxy-3-fluoro-nitrobenzene is also a chemical product. Looking at its name, we know that its structure is unique, containing dimethoxy, fluorine and nitro groups. This substance is widely used in the field of chemical industry and scientific research.
The synonym for this substance, or it can be called "2-fluoro-3,5-dimethoxy-nitrobenzene", although the description is slightly different, the reference is the same. As for the trade name, or depending on the manufacturer and the use, it all refers to this specific compound.
Chemical substances, although the names are different, are the same, and this 2,4-dimethoxy-3-fluoro-nitrobenzene is also one of them. Researchers should understand the relationship between its synonyms and trade names, in scientific research and production, so that this compound can be used to its fullest extent and contribute to the chemical industry and scientific research.
Safety & Operational Standards
Specifications for the safety and operation of 2,4-dimethoxy-3-fluoronitrobenzene
Fu 2,4-dimethoxy-3-fluoronitrobenzene is an important substance in chemical research. To use it properly, it must first clarify its safety and operation specifications.
In terms of safety, this substance has certain chemical activity and should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may react violently with certain substances, it should not be stored and transported with strong oxidants, strong acids, strong bases, etc. When handling, be sure to handle it with care to prevent leakage due to damaged packaging. If accidental leakage, immediately isolate the contaminated area and restrict personnel from entering and leaving. Emergency responders need to wear protective clothing, wear protective masks, and do not let leaks come into contact with combustible substances. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be constructed or dug for containment, and then properly handled.
In terms of operation specifications, experimenters should wear appropriate protective clothing, protective gloves and goggles. Operate in a fume hood to avoid inhalation of harmful vapors. Before use, read the relevant information carefully to be familiar with its physical and chemical properties and reaction characteristics. During the experiment, strictly follow the established steps and do not change without authorization. Accurately measure the required amount to avoid waste and excessive reaction. The reaction device needs to be stable and tightly connected to prevent materials from escaping. When heating, control the temperature and rate, and do not heat up suddenly. After the reaction is completed, properly dispose of the remaining materials and products, and do not dump them at will. Only by strictly observing safety and operating standards can we ensure the smooth progress of the experiment, protect the health of personnel, and promote the orderly progress of chemical research.
Application Area
Today there is a thing called 2,4-dimethoxy-3-fluoronitrobenzene, which is widely used in the field of chemical industry. It can be a key raw material in the synthesis of medicine. With its unique structure, it can help doctors make special drugs and treat various diseases in the world.
In the context of material research and development, it also shows extraordinary capabilities. It can participate in the creation of new materials, make materials specific, or increase their toughness, or change their conductivity, in the electronics, construction and other industries.
In the path of scientific research and exploration, it opens up new paths for scholars. Help them explore unknown chemical mechanisms and expand the boundaries of scientific cognition. Looking at this 2,4-dimethoxy-3-fluoronitrobenzene, in the fields of medicine, materials, and scientific research, it is like a starry night, guiding the way forward, and its function cannot be underestimated.
Research & Development
Today there is a thing called 2,4-dimethoxy-3-fluoronitrobenzene. We are chemical researchers to explore the way of its research and creation. The development of this thing involves many exquisite chemical methods. After repeated trials, we study the wonders of molecular structure and observe the requirements of reaction conditions.
At the beginning, the choice of raw materials is crucial, and it is necessary to be pure in order to build a successful foundation. During the reaction, the temperature, pressure, and catalyst allocation all need to be precisely controlled. If there is a slight difference, the result will be wrong.
After long-term research, optimization of steps, and improvement of techniques, the output of this product will gradually stabilize and the quality will also improve. In the future, we hope to be able to expand its use in the fields of medicine and materials, contributing to the progress of chemistry and the well-being of mankind, and moving forward unremittingly to reach a new frontier of research and innovation.
Toxicity Research
Toxicity of 2,4-dimethoxy-3-fluoronitrobenzene. This compound contains fluorine, nitro and other groups, or may be potentially toxic. According to various experiments, in animal experiments, if this substance is administered to test animals, some of them appear abnormal behavior, or appear to be sluggish, or appear to eat less. Dissect and observe the organs, liver, kidney or present damage characteristics, cell structure disorder, function or affected. In cell experiments, it is also seen that it has inhibitory effects on the growth of specific cell lines, or by interfering with cell metabolic pathways. In summary, 2,4-dimethoxy-3-fluoronitrobenzene has certain toxicity, and subsequent application and production should be done with caution to prevent it from causing harm to organisms and the environment.
Future Prospects
Fu 2,4-dimethoxy-3-fluoro-nitrobenzene is also a new compound. Looking at its structure, it contains fluorine, nitro, and dimethoxy groups. This unique structure contains extraordinary properties.
In the future development, it can be used to make special drugs. The introduction of fluorine groups, or the increase of lipid solubility of drugs, helps it absorb through membranes, and is more effective in treating diseases. It can also be used as a high-energy material, with its stability and activity, for optoelectronic equipment, to add new energy, and to expand the field of use.
Furthermore, in organic synthesis, it is an important intermediate. Through various reactions, a variety of compounds are derived, which is a rich chemical library.
Although its research is still in its infancy, with its characteristics, the future will be in the fields of medicine, materials, and synthesis, shining brightly, opening up new opportunities, and opening up endless possibilities.
Where to Buy 2,4-Dimethoxy-3-Fluoronitrobenzene in China?
As a trusted 2,4-Dimethoxy-3-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Dimethoxy-3-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-dimethoxy-3-fluoronitrobenzene?
2% 2C4-dimethoxy-3-chlorobenzylbenzene has many important uses in industry and scientific research.
In the field of organic synthesis, as a key intermediate, it can participate in the creation of many complex organic compounds. For example, in the synthesis route of specific drug molecules, it can gradually build a drug skeleton with specific pharmacological activities through its own unique chemical structure and a series of chemical reactions combined with other reagents. For example, when synthesizing some new drugs for the treatment of cardiovascular diseases, this compound plays an indispensable role in building the foundation, laying the foundation for the development and optimization of subsequent drugs.
In the field of materials science, it also shows unique value. It can be used to prepare polymer materials with special properties. By polymerizing with other monomers, the material can be endowed with better stability, corrosion resistance or optical properties. For example, when preparing high-end optical plastic materials, the introduction of this compound can optimize the optical refractive index of the material, improve its applicability in the manufacture of optical instruments, and make the produced optical components such as lenses have better performance.
In the agricultural field, it may also be used as an important raw material for the synthesis of new pesticides. Through rational molecular design and reaction, green pesticides with efficient control effect on specific pests and small impact on the environment can be prepared. For example, for some common pests that harm crops, synthetic pesticides based on them can precisely act on specific physiological targets of pests, inhibit the growth and reproduction of pests, ensure the healthy growth of crops, and contribute to the sustainable development of agriculture.
What are the physical properties of 2,4-dimethoxy-3-fluoronitrobenzene?
2% 2C4-diethoxy-3-formylbenzaldehyde, which is an important intermediate in organic synthesis. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly in the shape of light yellow to yellow crystalline powder. The color is relatively bright, and its unique color can be seen in sunlight.
Smell its smell, which has a special aromatic smell. However, this smell is not rich and pungent, but a milder aroma. Under a fine smell, its unique smell can be felt.
Measure its melting point, the melting point is about [X] ° C. At this temperature, the substance gradually melts from solid to liquid, achieving a phase transition; the boiling point is about [X] ° C. At this temperature, the liquid substance will rapidly vaporize.
In terms of its solubility, in organic solvents, such as ethanol, ether, dichloromethane, etc., it shows good solubility and can be miscible with these organic solvents to form a uniform solution; however, in water, its solubility is poor, and due to the molecular structure characteristics of the substance, it is difficult to dissolve in water with strong polarity.
Its density is higher than that of water. If it is mixed with water and left to stand, it will sink to the bottom of the water.
These physical properties are of great significance in the field of organic synthesis. Due to its special morphology, odor, melting and boiling point, solubility and density, it determines the way it participates in various chemical reactions and the reaction conditions. Chemists can reasonably design synthesis routes based on this, and use its characteristics to prepare more complex and functional organic compounds.
Is the chemical properties of 2,4-dimethoxy-3-fluoronitrobenzene stable?
The chemical properties of 2% 2C4-dimethyloxy-3-chlorobenzyl benzene are really related to its molecular structure and composition. This compound contains specific functional groups, such as chlorobenzyl and dimethyloxy, which have a great influence on its properties.
In terms of stability, the carbon-chlorine bond of the chlorobenzyl part is relatively active. Although the benzene ring has a certain stability and can disperse the electron cloud, the chlorine atom is electron-absorbing, which impairs the stability of benzyl carbocation. In the case of nucleophilic reagents, this carbon-chlorine bond is easily broken, leading to nucleophilic substitution reactions, so its stability at this level is not very high.
Dimethoxy is a power supply group, which can increase the electron cloud density of the benzene ring. During the aromatic electrophilic substitution reaction, the benzene ring will be more vulnerable to the attack of electrophilic reagents. Although this power supply effect changes the electron distribution of the benzene ring, it does not directly cause the overall structure to be unstable. On the contrary, due to the adjustment of the electron cloud, its reactivity is increased under certain reaction conditions.
Looking at its chemical environment again, if it is in a high temperature, strong acid-base or strong redox environment, the stability may be more challenged. At high temperature, the thermal motion of the molecule intensifies, the vibration of the chemical bond is enhanced, and the relatively weak carbon-chlorine bond may be more prone to fracture. Strong acid-base environment can catalyze reactions such as hydrolysis and affect the molecular structure. Strong oxidizing agents or reducing agents can also change the oxidation state of the atoms in the molecule due to redox reactions, breaking the original structure.
In summary, the stability of 2% 2C4-dimethyloxy-3-chlorobenzene is not absolute, and it can still maintain a certain stability under normal mild conditions; in case of specific reaction conditions or chemical reagents, its structure may change, showing different reactivity, and the stability will also change.
What are the preparation methods of 2,4-dimethoxy-3-fluoronitrobenzene?
The preparation method of 2% 2C4-dimethoxy-3-chlorobenzylbenzene is not directly recorded in the ancient book Tiangong Kaiwu, but inspiration can be found from the ideas and methods of preparing similar compounds by the ancients.
To prepare this substance, a suitable benzene substrate may be obtained first. This substrate needs to have a check point that can be substituted to facilitate subsequent reactions. In ancient times, although there was no advanced purification method today, relatively pure raw materials could be obtained by repeated distillation, extraction and other simple methods.
After the substrate is extracted, a suitable halogenating agent can be found to introduce chlorine atoms at a specific position. Although there are no modern abundant halogenated reagents in ancient times, halogen elements can be used to promote their substitution reaction with the substrate under suitable conditions. When reacting, pay attention to temperature, light and other conditions, or under mild light, let the halogenated agent react slowly with the substrate, so that the chlorine atom is precisely replaced to the 3-position to form a chlorine-containing intermediate.
Then, if you want to introduce 2% 2C4-dimethoxy group, you can look for reagents containing methoxy group. Or you can mix such reagents with chlorine-containing intermediates and use suitable catalysts to promote the reaction between the two. Ancient catalysts may be natural ores, metal oxides, etc. Although the catalytic efficiency is not as good as modern ones, you can find suitable substances through exploration. In this process, it is crucial to control the process and rate of the reaction. The degree of reaction can be judged by observing reaction phenomena such as color change and precipitation formation.
In the preparation process, separation and purification are also key steps. In ancient times, filtration, recrystallization and other methods were used to separate the product from the reaction system to remove impurities to improve the purity of the product. Although these methods are relatively rough, they can be used with care. In this way, following the wisdom and methods of the ancients, the preparation path of 2% 2C4-dimethoxy-3-chlorobenzylbenzene can be explored.
What are the precautions for storing and transporting 2,4-dimethoxy-3-fluoronitrobenzene?
2% 2C4-dimethoxy-3-formylbenzene requires attention to many matters during storage and transportation. This substance is a chemical substance, and its properties may be more active. When storing, the first environment should be selected. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may be flammable, it is easy to cause danger in case of open flames and hot topics, so the warehouse must strictly prohibit fireworks.
Storage temperature is also critical. If the temperature is too high, it may cause chemical reactions, causing it to deteriorate or cause safety accidents. At the same time, it should be stored separately from oxidants, acids, and bases to avoid mixed storage. Due to its chemical properties, contact with these substances or produce violent reactions, threatening the safety of personnel and facilities.
In terms of transportation, strict regulations need to be followed. Transportation vehicles should ensure good airtightness to prevent leakage. During loading and unloading, it must be handled lightly to avoid collisions and falls, so as to prevent material leakage caused by damaged packaging. Transportation personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. During transportation, close attention should be paid to the condition of the goods, such as temperature, whether the packaging is in good condition, etc. Once any abnormality such as leakage is detected, emergency measures should be taken immediately, evacuate the surrounding personnel, and deal with the leakage in the correct way to avoid polluting the environment and causing greater harm. This ensures the safety of 2% 2C4-dimethoxy-3-formylbenzene during storage and transportation, reducing latent risk.