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2,4-Difluorobenzenethiol

2,4-Difluorobenzenethiol

Hongda Chemical

Specifications

HS Code

430388

Chemical Formula C6H4F2S
Molecular Weight 146.16
Appearance Typically a liquid (but appearance can vary based on purity and conditions)
Solubility In Water Insoluble (aromatic thiols generally have low solubility in water due to non - polar nature of the benzene ring)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, diethyl ether, dichloromethane (due to its organic nature)
Odor Characteristic, likely pungent and sulfur - like (common for thiol compounds)

As an accredited 2,4-Difluorobenzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,4 - difluorobenzenethiol packaged in a sealed, corrosion - resistant bottle.
Storage 2,4 - difluorobenzenethiol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Due to its potential toxicity and reactivity, it should be stored separately from incompatible substances to prevent hazardous reactions.
Shipping 2,4 - difluorobenzenethiol is a chemical. Shipping should be in accordance with regulations for hazardous substances. It must be properly packaged in suitable containers to prevent leakage during transit.
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2,4-Difluorobenzenethiol 2,4-Difluorobenzenethiol
General Information
Historical Development
Fu 2,4 - Difluorobenzenethiol, organic compounds are also. Tracing back to its origin, at the beginning, the academic community was still shallow in the study of fluoromercaptan compounds. However, times have changed and science and technology have advanced, and researchers have begun to focus on this.
In the early years, the synthesis of this compound was difficult and the yield was quite low. However, after years of unremitting research, Zhu Xian improved the synthesis method and optimized the reaction conditions. As a result, the yield gradually increased, and the purity also increased.
The field of its application has also become wider with the depth of research. At first, it was only used for specific experiments, and later it emerged in the fields of medicine, materials, etc. The historical evolution of this compound relies on the diligence and wisdom of researchers of all generations to achieve today's achievements and pave the way for more exploration in future generations.
Product Overview
2,4-Difluorothiophenol is also an organic compound. It may be a colorless to light yellow liquid with a special mercaptan odor. This compound is widely used in the field of organic synthesis.
2,4-Difluorothiophenol contains fluorine atoms and thiol groups. The introduction of fluorine atoms endows it with unique physical and chemical properties, making it potentially useful in pharmaceutical chemistry, materials science and other fields. In drug development, it may be used as a key intermediate to construct molecular structures with specific biological activities.
Preparation of 2,4-difluorothiophenol, or by the reaction of specific halogenated aromatics with sulfur-containing reagents. The reaction process requires fine control of reaction conditions, such as temperature, reactant ratio, etc., to ensure the purity and yield of the product.
However, this substance may have certain toxicity and irritation. When operating, strictly follow safety procedures and take protective measures to ensure the safety of the experimenter and the harmlessness of the environment.
Physical & Chemical Properties
2,4-Difluorothiophenol is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, or in a liquid state, it has a special odor. Its boiling point and melting point are the key parameters characterizing its state change, which are related to its state in different temperature environments. And the density cannot be ignored, which is related to its distribution characteristics in the medium.
In terms of its chemical properties, thiophenol groups have active chemical activities. It can react with many reagents, such as nucleophilic substitution reactions, sulfur atoms of thiophenol groups can be used as nucleophilic reagents to react with substrates such as halogenated hydrocarbons to form new sulfur-containing compounds. And because of the presence of fluorine atoms, it affects the electron cloud distribution of molecules, causing its chemical properties to be different from ordinary thiophenol, or unique in reactivity and selectivity. All these physical and chemical properties are important in organic synthesis, materials science and other fields.
Technical Specifications & Labeling
Today there is a thing called 2,4 - Difluorobenzenethiol. To clarify its technical specifications and identification (product parameters), it is necessary to study its quality in detail. The technical specifications of this product are related to purity, impurity content, etc. The purity must be excellent, and impurities must be strictly controlled. Its identification (product parameters) should state its chemical structure and characteristics. If the chemical structure needs to be accurately described, the characteristics involve physical and chemical properties. Physical properties or the genus of melting point and boiling point, chemical properties are related to its reactivity. Only with this technical specification and identification (product parameters) can it be properly disposed of during use and storage to ensure its stability and suitability for use.
Preparation Method
The raw materials and production process, reaction steps and catalytic mechanism of this 2,4-Difluorobenzenethiol are quite critical. Take an appropriate amount of fluorobenzene and brominate it to obtain 2,4-dibromofluorobenzene. React with sodium hydride as an agent at a specific temperature and pressure, this is the key step. During the reaction, the temperature is controlled at 60 to 80 degrees, the pressure is about one to two atmospheres, and after several hours, the reaction is completed, and it is purified by distillation. The catalytic mechanism used is a metal salt as a catalyst to promote the reaction. In this way, it can be made into 2,4-Difluorobenzenethiol, with good yield and excellent quality, which can be used for subsequent chemical industries.
Chemical Reactions & Modifications
The chemical and anti-chemical modification of di- and tetrafluoro-thiophenol is being studied today. The properties of this compound are special, and the way of anti-chemical can be investigated. Its chemical and anti-chemical, often involve the activity of thiophenol groups, and fluorine atoms also affect its anti-chemical process. If it is encountered, thiophenol groups are easy to reduce, but due to the low performance of fluorine atoms, the density of benzene particles is changed, and the anti-chemical activity is changed.
As for modification, other groups can be introduced into benzene to reduce its properties. If it is connected with nitrogen-containing groups, it may increase its solubility or change its solubility. Or modify thiophenol groups to reduce its anti-chemical activity. In this research, we hope to expand its application in the fields of materials, materials, etc., to understand the wonders of its transformation and modification, so as to create more useful things.
Synonyms & Product Names
2,4-Difluorobenzenethiol is an important chemical substance. Its synonyms and trade names are also called in many ways in the industry. In ancient chemical investigations, the naming of such substances often had specific rules. Or according to its chemical structure, properties, or because of its use.
View 2,4-Difluorobenzenethiol, or have synonyms related to its chemical composition, such as the name related to the combination of fluorine atoms with benzene rings and thiol groups. Trade names may be based on factors such as commercial promotion and manufacturer characteristics. In the past, when chemists investigated this substance, they also analyzed its different names in detail to clarify its essence and characteristics, which helped the inheritance and development of chemical knowledge, so that future generations could explore its mysteries more smoothly on the road of chemical research due to the clarity of synonyms and trade names.
Safety & Operational Standards
2,4-Difluorothiophenol is an important substance in chemical research. During its experimental preparation and application, safety and operating standards are of paramount importance.
The first word is safety. This substance is toxic and irritating, and it can be dangerous to health if smelled, touched or taken by mistake. Therefore, the place where the experiment is located must be well ventilated to disperse harmful gases. Researchers need to wear strict protective equipment, such as laboratory clothes, gloves and goggles, to avoid contact between skin and eyes. If you accidentally touch it, rinse it with plenty of water as soon as possible, and seek medical attention in severe cases. Storage should also be careful, placed in a cool, dry and ventilated place, away from fire and heat sources, and should also be stored separately from oxidants, acids, etc., to prevent dangerous reactions.
Next talk about the operating specifications. When weighing, it is appropriate to use precise instruments and measure accurately according to the experimental requirements. During the dissolution process, choose the appropriate solvent according to its solubility, and pay attention to the stirring speed and temperature to promote its full dissolution. During the reaction stage, strictly control the temperature, time and proportion of reactants and other conditions. Due to poor reaction conditions, different products or side reactions are caused. After the reaction, the separation and purification of the product should also be carried out according to specifications, such as extraction, distillation, recrystallization and other methods, to ensure the purity of the product.
In short, the research on 2,4-difluorothiophenol is based on safety and operating standards. Only by strictly adhering to the guidelines can researchers ensure the smooth operation of the experiment, protect their own safety, and obtain more reliable results.
Application Area
Today there is a thing called 2,4 - Difluorobenzenethiol. The application field of this thing is quite wide. In the field of medicine, it may help to develop special drugs, with its unique properties, act on human lesions and cure various diseases. In the chemical industry, it can be a key raw material, and through exquisite craftsmanship, it can be made into various high-quality chemical products, expanding its uses. In the research and development of materials, it may be able to improve the properties of materials, making them more resilient, stable and other excellent characteristics. All these applications depend on the characteristics of this thing. With time and in-depth investigation, its potential in various fields will be fully revealed, and it will seek many benefits for the world.
Research & Development
In recent years, Yu devoted himself to the exploration of chemical substances, with particular attention to 2,4-Difluorobenzenethiol. Its unique structure and unique properties have great potential in the field of organic synthesis.
The first time this substance was involved was because of its activity in specific reactions. The Yu Si team investigated its reaction mechanism in detail and explored the transformation path under different conditions. After repeated experiments, it was known that it interacted with a variety of reagents, which was the cornerstone of research and development.
The research and development process was difficult. Such as the improvement of reaction yield and the inhibition of side reactions. However, the team made unremitting efforts to search the classics, learn from the methods of the past, and combine modern technology, and finally achieved something. The optimized synthesis process results in a significant increase in yield and better product purity.
Looking to the future, 2,4-Difluorobenzenethiol is expected to shine in the preparation of new materials. Yu et al should continue to study and expand its applications, hoping to contribute to the development of the chemical field.
Toxicity Research
The study of poisons is related to the safety of people's livelihood. Today there are 2,4 - Difluorobenzenethiol of this substance, and the study of its toxicity is quite important.
When observing this substance, its nature is unknown, everyone needs to be cautious. Detailed observation of its chemical and physical properties, explore its impact on the environment and organisms. Or enter the water and soil, observe the change of water and soil; or sense life, observe the state of life.
The study of toxicity is not a temporary effort. It takes months and years to study it carefully. Consider the difference in its concentration, the duration of contact, the difference in what you feel, and the difference in toxicity. Hope to get the real chapter, in order to avoid its harm, keep everyone healthy, and protect the peace of the environment. Therefore, it is necessary to fulfill the important task of toxicity research.
Future Prospects
This object is like a shining star in our research and pursuit, guiding the direction of future expansion. It is unique in nature, exquisite in structure, and contains endless potential. Although it is only a glimpse at the moment, looking forward to the future, it is expected to shine in various fields. Or it can be used to create exquisite medicines to treat diseases; or it can help the research and development of high-tech materials, adding bricks and tiles. Although there may be thorns in the road ahead, we scientific researchers should move forward with a tenacious heart. We hope to make unremitting research, explore its profound mysteries, and expand its broad application, so that it will shine in the future, bring well-being to the world, and live up to our expectations for the future.
Where to Buy 2,4-Difluorobenzenethiol in China?
As a trusted 2,4-Difluorobenzenethiol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Difluorobenzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluorothiophenol?
2% potassium 2C4-diethylbenzoate has a wide range of uses. In the field of medicine, it is often a key raw material for the synthesis of many drugs. Due to its specific chemical structure and activity, it can be chemically modified to produce drugs with different effects, such as some drugs with anti-inflammatory and antibacterial effects. During the synthesis process, this compound is often an important intermediate, which helps to construct drug active structures and achieve the purpose of treating diseases.
In the chemical industry, it is also an important component in the preparation of special materials. In the synthesis of polymer materials such as plastics and rubber, it can be added as a modifier. By participating in the polymerization reaction, the physical and chemical properties of the material can be changed, such as improving the flexibility and stability of the material, enhancing its anti-aging and weather resistance, and then expanding the application range of the material in different environments.
In the fragrance industry, 2% potassium 2C4-diethylbenzoate can be used to prepare specific fragrances due to its unique smell. After fine proportions and process treatment, it can endow fragrances with a unique aroma, which can be used in perfumes, air fresheners, detergents and other products to add unique fragrance to the product and enhance the market competitiveness of the product.
In the agricultural field, it can be used as a raw material for plant growth regulators. Appropriate use can regulate the growth process of plants, promote the development of plant roots, and enhance plant stress resistance, such as drought resistance, cold resistance, and disease resistance, thereby improving crop yield and quality, and contributing to the efficient and sustainable development of agriculture.
What are the physical properties of 2,4-difluorothiophenol?
2% 2C4-diethylbenzenesulfonic anhydride is one of the organic compounds. Its physical properties are quite worthy of investigation.
Looking at its appearance, under normal temperature and pressure, it often appears as a colorless to slightly yellow liquid. The texture is clear and transparent, like clear water. Under light, it can be seen flowing and refracting a faint brilliance.
Smell its smell, which has a pungent smell. This smell is quite strong. If people get close, they will feel pungent. This is a warning to everyone to be cautious.
When it comes to boiling points, it is about a certain temperature range. At this temperature, its molecules gain enough energy to break free from each other and change from liquid to gaseous. The characteristics of its boiling point are of great significance in the distillation, separation and other processes of chemical production. According to the difference in boiling point, it can be effectively separated from the mixture.
Melting point is also an important physical property. At a specific low temperature, the substance gradually solidifies from liquid to solid. The exact value of the melting point affects its storage and transportation conditions. It is necessary to consider the appropriate temperature environment according to the melting point to prevent its state from changing and affecting the quality.
In terms of solubility, it is soluble in many organic solvents, such as common ethanol, ether, etc. This property makes it widely used in the field of organic synthesis. It can be used as a reaction medium to promote various chemical reactions to proceed more efficiently. It also helps to dissolve other reactants, increase the reaction contact area, and improve the reaction rate and yield.
Density is also a physical property that cannot be ignored. Compared with water, it has a specific density value. This value is related to its distribution in liquid mixtures and plays an important guiding role in the stratification, extraction and other steps of related chemical operations.
In summary, the physical properties of 2% 2C4-diethylbenzenesulfonic anhydride play a key role in many fields such as chemical industry and organic synthesis. Only by understanding its properties can its application be better controlled.
Is the chemical properties of 2,4-difluorothiophenol stable?
The chemical properties of 2% potassium 2C4-diethylbenzoate are quite stable. Cover because of its unique molecular structure, the bonds between atoms are firm, and external forces are not easy to change them abruptly.
For this compound, the elements of carbon, hydrogen, oxygen, and potassium are connected in a specific way to build a stable structure. Carbon-carbon bonds and carbon-hydrogen bonds have considerable strength, laying the foundation for the stability of the molecule. Its benzene ring structure is maintained by conjugated π bonds, which endows the molecule with additional stability, making the benzene ring less susceptible to the attack of general chemical reagents and causing structural disintegration.
Furthermore, potassium carboxylate groups (-COOK) also play an important role in stability. The ionic bond between the potassium ion and the oxygen atom of the carboxyl group, although electrostatic, is also very stable. Under normal circumstances, this ionic bond is not easy to break, unless it encounters extreme chemical conditions such as strong acids, it can promote the dissociation of potassium ions, and the carboxyl group is converted to the carboxylic acid form.
Under normal conditions, 2% potassium 2C4-diethylbenzoate does not react rapidly with common substances such as water and oxygen within the common temperature and pressure range. In organic solvents, although its solubility characteristics vary depending on the type of solvent, its molecular structure remains relatively stable during the dissolution process, and only physical dispersion occurs, rather than chemical qualitative change. Therefore, 2% potassium 2C4-diethylbenzoate exhibited good structural resistance and chemical inertness in conventional chemical and physical environments.
What are the synthesis methods of 2,4-difluorothiophenol?
The synthesis of 2% 2C4-diethylbenzophenone covers various pathways. One method is to use acetophenone and bromoethane as the starting materials, and to carry out alkylation reaction under the catalysis of alkali. Alkali, such as sodium alcohol, can take alpha-hydrogen from acetophenone and generate carbon negative ions. This carbon negative ion nucleophilic attacks the carbon of bromoethane, forms a carbon-carbon bond, and then obtains 2% 2C4-diethylbenzophenone. The reaction conditions require appropriate temperature and reaction time. If the temperature is too high, the side reaction will occur, and if it is too low, the reaction will be delayed.
Another method uses ethyl benzoate and diethyl zinc as raw materials. Diethylzinc has an active alkyl group and can perform nucleophilic addition to the carbonyl group of ethyl benzoate. During the reaction, ethyl benzoate is mixed with an appropriate amount of catalyst, and then diethylzinc is slowly added. This process needs to be carried out in an anhydrous and oxygen-free environment, and diethylzinc reacts violently in contact with water and oxygen. After the reaction is completed, after post-treatment, such as extraction, distillation, etc., pure 2% 2C4-diethylbenzophenone can be obtained.
Furthermore, it can be synthesized from m-diacetylbenzene and acylating reagents. Acylating reagents such as acetyl chloride or acetic anhydride, catalyzed by Lewis acid (such as aluminum trichloride), the benzene ring of m-diethylbenzene undergoes Fu-gram acylation reaction. Aluminum trichloride interacts with the acylating reagent to generate an electrophilic reagent, attacks the m-diethylbenzene ring, and introduces an acyl group at a suitable position to finally obtain 2% 2C4-diethylbenzophenone. After the reaction, the product is separated and purified to achieve the required purity. This number method has its own advantages and disadvantages. In practical application, it should be weighed according to the availability of raw materials, cost, and difficulty of reaction conditions.
What are the precautions for storing and transporting 2,4-difluorothiophenol?
2% 2C4-diethylbenzoic anhydride is a kind of organic compound. When storing and transporting, it is necessary to pay attention to many matters to ensure safety.
When storing, the first environmental conditions. It should be placed in a cool, dry and well-ventilated place. This is because if the substance is in a high temperature and humid place, or causes chemical changes, or even causes deterioration. High temperature can promote its reactivity to increase, while humid air may neutralize with it, damaging its quality. In addition, it should be kept away from fire and heat sources, because it is flammable, and it is easy to burn in case of open flames and hot topics. And it needs to be stored separately from oxidants, acids, bases, etc., to prevent interaction and dangerous reactions.
When transporting, the packaging must be tight. Select appropriate packaging materials to achieve shock-proof and leak-proof effects. Make sure that the material does not leak during the transportation turbulence. At the same time, the transportation vehicle must also meet safety standards and be equipped with corresponding fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers should abide by traffic rules, drive slowly and steadily, and avoid sudden braking, sharp turns, etc., to prevent damage to the packaging. If leakage occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding people and prevent poisoning and fire accidents.
All of these are the keys to the storage and transportation of 2% 2C4-diethyl benzoic anhydride. Practitioners should observe them carefully to protect the safety of life and property.