2,4-Difluorobenzeneamine

Hongda Chemical

Specifications

HS Code	237301
Chemical Formula	C6H5F2N
Molar Mass	129.11 g/mol
Appearance	Colorless to light yellow liquid
Boiling Point	186 - 188 °C
Melting Point	16 - 18 °C
Density	1.23 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Flash Point	71 °C
Odor	Characteristic amine - like odor
Cas Number	367-25-9

As an accredited 2,4-Difluorobenzeneamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	250 - gram bottle of 2,4 - difluorobenzeneamine, well - sealed for chemical storage.
Storage	2,4 - difluorobenzeneamine should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances such as strong oxidizing agents. Store it in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air and moisture, which could potentially lead to degradation or dangerous reactions.
Shipping	2,4 - difluorobenzeneamine is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling indicating its nature, to ensure safe transportation and prevent leakage.

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General Information

Historical Development

2,4-Difluorobenzamine is one of the chemical products. Its historical evolution began with the exploration of the unknown in the past. In the past, many chemists have deeply studied the wonderful theory of the change of things. At the beginning, the relevant research was still ignorant and little was known. However, the public has been unremitting, after countless attempts, taking experiments as the path, thinking as the candle, and gradually understanding its nature.
The years go by, science and technology advance day by day, and the research is more and more detailed. In the method of synthesis, from rough and simple to exquisite, the process changes, and strives for purity and goodness. Its application also expands with cognition, from a corner of limitation, and gradually involves the field of diversity. The functions that were not expected in the past are now revealed. The historical development of this product is like a long scroll, from shallow to deep, witnessing the rugged and brilliant road of chemistry.

Product Overview

There is a substance called 2,4-Difluorobenzeneamine. This is an organic compound whose molecule contains a difluorine and an amino group, which is connected to the benzene ring.
Looking at its physical properties, it may be a colorless liquid at room temperature, with a special odor. The melting point depends on the intermolecular force. It has good solubility in organic solvents, but slightly less in water.
In terms of its chemical properties, the amino group is alkaline and can form salts with acids. The conjugate structure of the benzene ring allows it to participate in many electrophilic substitution reactions. The introduction of difluorine atoms affects the distribution of electron clouds in the benzene ring, and the reactivity and selectivity are different.
This compound is widely used in the fields of medicine and materials. In medicine, it may be a key intermediate for the synthesis of specific drugs, with its special structure and activity, acting on specific targets. In the material industry, it can be used as a raw material for the synthesis of functional materials, endowing materials with novel properties.
Preparation method, or through multi-step reaction, starting from easy-to-obtain raw materials, through halogenation, amination and other steps. Each step requires controlled conditions to achieve high yield and high purity.

Physical & Chemical Properties

Today there is a thing named 2,4 - Difluorobenzeneamine. Its physical and chemical properties are related to our research. Looking at its physical properties, under room temperature, or in a specific state, it has a unique color, taste and phase state. Its melting point and boiling point are the keys to characterizing its characteristics. In terms of solubility, among various solvents, there may be different manifestations, or it is easily soluble in certain types of solvents, or insoluble or even insoluble.
In terms of its chemical properties, the position of fluorine and amino groups in its molecular structure makes it have special reactivity. It can react chemically with many reagents, either nucleophilic or electrophilic, depending on the reaction conditions. The bond energy between atoms and the distribution of electron cloud determine the chemical behavior of the atoms. The study of these physical and chemical properties has great benefits in their application and preparation, and the potential of them in different fields can be explored.

Technical Specifications & Labeling

2,4-Difluoroaniline, its process specifications and identification (product parameters) are the key. Looking at this product, its color is pure and taste is positive, it is a high-quality chemical preparation.
In terms of its process specifications, the selection of raw materials must be high-quality, and the ratio is accurate. During the reaction, the temperature and pressure must be strictly controlled, and the operation according to a specific timing can ensure the purity and quality of the product. And the preparation process needs to be interlocking, and the impurities are removed finely and subtly to ensure that the finished product is flawless.
As for the identification (product parameters), the content must reach a very high standard, and the impurity content is minimal. The appearance is in a specific state, and the smell is also in accordance with the established rules. These are all important markers for measuring the advantages and disadvantages of 2,4-difluoroaniline, which are related to its application effectiveness in various fields of chemical industry.

Preparation Method

The method of making 2,4-Difluorobenzeneamine involves raw materials and production processes, reaction steps and catalytic mechanisms. First, fluorobenzene and the like are taken as the initial raw materials, and a specific catalyst is used to react with amino-containing reagents under moderate temperature and pressure. The reaction steps are rigorous, the temperature is controlled at tens of degrees Celsius, and the pressure is fine-tuned according to the reaction process to ensure a smooth reaction. The catalytic mechanism is also key. The catalyst used is highly active, which can reduce the activation energy of the reaction and promote the efficient progress of the reaction. The ratio of raw materials is accurate, and the amino reagent is slightly excessive, which makes the reaction shift towards the direction of product formation. After this series of operations, a purer 2,4-Difluorobenzeneamine can be obtained, which is the foundation for subsequent applications.

Chemical Reactions & Modifications

In recent years, the study of chemical technology, in 2,4 - Difluorobenzeneamine this thing, quite laborious. Its transformation is wonderful, and the opportunity for change is all important for research.
At the beginning, I tried to follow the old method, although it should be there, the effect is not perfect. The yield is not abundant, and the quality is also slightly flawed. I think about it, the way of transformation is about change. Then change its conditions, adjust temperature and pressure, and make it easier to match reagents.
Not much, the fruit has improved. The yield is gradually rising, and the quality is more pure. This is the power of transformation. Looking at the past, all the sages have studied things, and they have also undergone many changes, and they have obtained good results. Although I have made small achievements in the research of this thing, the road ahead is still far away. I must be diligent and agile, and adapt to the changes, dig deep into its mysteries, and hope to obtain better methods, so that the products of 2,4-Difluorobenzeneamine can reach the realm of perfection.

Synonyms & Product Names

About the synonyms and trade names of 2,4-difluorobenzamine
There is a chemical substance 2,4-difluorobenzamine. In the field of chemical research, synonyms and trade names are quite critical. Covered synonyms can help researchers understand each other in different literatures, and trade names are related to market circulation.
This 2,4-difluorobenzamine may have aliases to meet the needs of different academic expressions. Although these aliases are different from common names, they all refer to the same. As for the trade name, it is used by the manufacturer for promotion in the market, or due to the unique formula and process, it is attached with a special name.
Our chemical researchers, when exploring this substance, must study its synonyms and trade names in detail. To understand its synonyms, you can read the writings of various schools without ambiguity; to know its trade names, you can observe changes in market supply, which is beneficial for research and acquisition, cooperation and exchange. Therefore, synonyms and trade names are essential items that we cannot ignore in our research on 2,4-difluorobenzamine.

Safety & Operational Standards

The safety and operation of 2,4-difluoroaniline
Fu 2,4-difluoroaniline is an important substance in chemical research. In its experimental and production process, safety and operation standards are of paramount importance.
The first word is safety. This substance is toxic to a certain extent, and touching or inhaling its vapor can harm human health. Therefore, when handling, it is necessary to wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent the skin and respiratory tract from coming into contact with it. And it must be operated in a well-ventilated place, so that the exhaust gas can be discharged quickly to avoid its accumulation.
Furthermore, about storage. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its exposure to open flames, hot topics or the risk of explosion, it should not be mixed with oxidants, acids, etc., to prevent dangerous chemical reactions.
As for the operating specifications. When using, the action should be slow and careful to avoid its splashing. If it is accidentally splashed on the skin, it should be rinsed with a large amount of water immediately, followed by a specific antidote treatment, and medical treatment. If taken in the experiment, when accurately measured, slowly add the reaction system according to the experimental procedures, and closely monitor the reaction status to prevent accidents.
In waste disposal, it should not be ignored. Wastes containing 2,4-difluoroaniline must be properly collected and disposed of in accordance with relevant laws and regulations, and should not be disposed of at will to avoid polluting the environment.
In short, in the research and application of 2,4-difluoroaniline, strict adherence to safety and operating standards can ensure the safety of personnel, protect the purity of the environment, and enable the research and production to proceed smoothly.

Application Area

2,4-Difluoroaniline has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new antibacterial and antiviral drugs. Because of the structure of difluoride, it gives the drug unique activity and better bioavailability.
In the development of pesticides, it can derive high-efficiency insecticides and fungicides. With its special chemical properties, it can accurately act on pests and bacteria to improve the control effect.
Also used in materials science. High-performance polymers can be synthesized, which have good thermal stability and mechanical properties, and are suitable for high-end fields such as aerospace. These are all important applications of 2,4-difluoroaniline, contributing to the progress of various industries.

Research & Development

The rise of modern chemistry is increasingly detailed in the study of substances. Today there is a thing, named 2,4-Difluorobenzeneamine, which our generation has studied for a long time, and its properties and its system have been obtained.
At the beginning, I explored its properties, knowing that it is in various solvents, its solubility is different, and it reacts with other substances, and it also has unique characteristics. If you want to make good use of it, you must understand its properties, and you can obtain its benefits and avoid its harm.
As for the method of preparation, after repeated trials, you can get several ways. Or take this as the beginning and transform it in several steps; or choose it as the basis and change its structure to form. However, the advantages and disadvantages of each method are mutually exclusive, or the cost is high, or the steps are cumbersome.
We aim to improve, optimize the preparation method, reduce its cost, simplify its steps, and make this product more widely used. And hope to explore its new way and develop its new energy, so that it can be used in the fields of medicine and materials, so as to benefit the world.

Toxicity Research

Toxicity of 2,4-Difluorobenzeneamine. This substance has a unique chemical structure and contains fluorine atoms, which may affect its toxicity. Take animals as a test to observe its state after ingestion and exposure. See the test animals have the appearance of slow movement and reduced food intake. After analysis, it may damage the animal's nervous system and digestive system. Study at the cellular level to observe its effect on cell viability and morphology. See cell morphology changes, and viability also decreases. In summary, 2,4-Difluorobenzeneamine has a certain toxicity. Its toxicological mechanism should be studied in detail in the future to provide a solid basis for the protection and application of this substance to avoid its harm to organisms and the environment.

Future Prospects

Today there is a thing called 2,4 - Difluorobenzeneamine. Our generation is a chemical researcher, and we are full of hope for the future of this thing.
This thing has unique properties, or it will shine in the field of medicine. Looking at the current medical research path, we are seeking precise and specific drugs. 2,4 - Difluorobenzeneamine Because of its specific molecular structure, it may become a key agent, helping to create new specific drugs, cure various diseases, and solve the suffering of patients.
In the field of materials, there is also potential. The rise of new materials requires unique raw materials. It may be the cornerstone to give birth to new materials with strong, durable and special properties, which can be used in aviation, electronics and other fields to promote science and technology.
Although there may be thorns ahead, our researchers, with perseverance, hope to lead 2,4-Difluorobenzeneamine to a bright future with wisdom and sweat, and contribute to the progress of the world.

Where to Buy 2,4-Difluorobenzeneamine in China?

As a trusted 2,4-Difluorobenzeneamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2,4-Difluorobenzeneamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluoroaniline?

2% 2C4-diethoxyacetophenone, its main uses are as follows:
This substance is indispensable in the field of fragrances. Because of its unique aroma, it is often used by perfumers as a raw material for blending fragrances. In the formulas of various fragrances such as floral and oriental fragrances, its shadow can be found, giving the essence a different flavor and level, making its aroma more fragrant and lasting. In perfumes, cosmetics, detergents and other products, it adds a charming fragrance and enhances the olfactory experience of the product.
In the field of pharmaceutical synthesis, it is also a key intermediate. It is used as a starting material or an important intermediate in the preparation of many drugs. Through a series of chemical reactions, its structure can be modified to derive compounds with specific pharmacological activities. For example, in the synthesis path of some cardiovascular drugs and nervous system drugs, 2% 2C4-diethoxyacetophenone is used as the basic raw material to construct the core skeleton of the drug through multi-step reactions, laying the foundation for the development and production of innovative drugs.
In the field of organic synthesis, it also plays an important role. Because of its specific functional groups in the molecular structure, it can participate in many organic reactions, such as nucleophilic substitution, condensation reactions, etc. Organic chemists use these reaction characteristics as key building blocks to construct complex organic molecular structures, providing the possibility for the creation of new materials and functional compounds, and promoting the development and progress of organic synthetic chemistry.

What are the physical properties of 2,4-difluoroaniline?

2% 2C4-diethylaniline, this substance is an organic compound. Its physical properties are quite unique.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow oily liquid, and after sunlight, the color may gradually darken. It has a special amine odor, and the smell is quite significant.
When it comes to the boiling point, it is about 216-218 ° C. At this temperature, the substance changes from liquid to gaseous. The melting point is -38 ° C. When the temperature drops below this point, it solidifies from liquid to solid. The relative density is about 0.93 (water = 1), which means that its density is slightly higher than that of water. If it is mixed with water, it will sink to the bottom of the water.
2% 2C4-diethylaniline is insoluble in water, which is due to its molecular structure characteristics, and the interaction between water molecules is weak, making it difficult to mix with each other. However, it is soluble in organic solvents such as ethanol, ether, and chloroform, because these organic solvents and 2% 2C4-diethylaniline molecules can form a similar interaction force, which conforms to the principle of "similar phase dissolution".
In addition, 2% 2C4-diethylaniline has a certain volatility and can evaporate slowly in air. Its vapor relative density is about 4.74 (air = 1), which is heavier than air, so the vapor is mostly close to the ground.

What are the chemical properties of 2,4-difluoroaniline?

2% 2C4-diethylaniline has unique chemical properties. This substance is a light yellow to amber oily liquid with a special odor, and it is easy to darken when exposed to light or stored for a long time.
In terms of physical properties, its boiling point is quite high, reaching 216-218 ° C, which means that it needs a higher temperature to boil into a gaseous state. The relative density is about 0.93-0.94, indicating that it is slightly less dense than water. At the same time, it is insoluble in water, but soluble in organic solvents such as ethanol and ether. This solubility characteristic is related to its molecular structure.
Chemically, 2% 2C4-diethylaniline is weakly basic due to the presence of amino groups. The nitrogen atom in the amino group has a lone pair of electrons, which can accept protons and can react with acids to form salts. In the field of organic synthesis, this basic property is very important and can be used to prepare various derivatives. Moreover, the hydrogen atom on the benzene ring changes its activity due to the influence of amino and ethyl groups, and can undergo substitution reactions. For example, under suitable conditions, it can be substituted with halogenated hydrocarbons, acyl halides and other reagents, and other groups can be introduced into the benzene ring to construct organic compounds with more complex structures. However, during these reactions, strict control of reaction conditions, such as temperature, catalyst type and dosage, is required to ensure that the reaction proceeds in the desired direction.
Due to its chemical properties, 2% 2C4-diethylaniline is widely used in dyes, medicine and other industries. In the dye industry, it can be used as an intermediate for synthesizing dyes of a specific color, through its participation in the reaction, endowing the dye with unique structure and color properties. In the field of medicine, it can also be used as a key raw material for synthesizing some drugs, using its chemical activity to construct a key part of drug molecules.

What is the production method of 2,4-difluoroaniline?

The preparation method of 2% 2C4-diethoxy acetophenone is as follows:
To prepare 2% 2C4-diethoxy acetophenone, acetophenone can be started. First, acetophenone is heated with ethanol and sulfuric acid. In this reaction, sulfuric acid is used as a catalyst to promote the substitution reaction of acetophenone with ethanol. The ethoxy group of ethanol (-OC ² H) gradually replaces the hydrogen atom on the phenyl ring of acetophenone. Under appropriate reaction temperature and time control, a mixture of 2-ethoxy acetophenone and 4-ethoxy acetophenone can be obtained.
Subsequently, the mixture is further reacted with ethanol and a larger amount of sulfuric acid at a higher temperature and for a longer time, prompting another ethoxy group to replace the remaining active hydrogen atoms, and finally generate 2% 2C4-diethoxyacetophenone. After the reaction, the sulfuric acid needs to be neutralized in alkali solution, and then the product can be separated and purified by distillation and extraction.
Acetyl chloride and resorcinol can also be used as raw materials. First, Friedel-Crafts acylation reaction is carried out under the catalysis of Lewis acid (such as aluminum trichloride) to generate 2-acetylresorcinol. After that, 2-acetylresorcinol is reacted with haloethane (such as bromoethane) under basic conditions (such as potassium carbonate), and the ethoxy group of the haloethane replaces the hydrogen of the phenolic hydroxyl group to obtain 2% 2C4-diethoxyacetophenone. The product is purified by washing, drying, recrystallization, etc., to obtain pure 2% 2C4-diethoxyacetophenone.

What are the precautions for storing and transporting 2,4-difluoroaniline?

2% 2C4-diethylaniline is an organic compound. During storage and transportation, the following things should be paid attention to:
First, storage. It is advisable to choose a cool and ventilated warehouse, away from fires and heat sources. Because the substance is flammable, it can cause combustion in case of open flames and hot topics, posing a threat to the surrounding environment and personal safety. The warehouse temperature should not exceed 37 ° C to prevent excessive temperature from causing its volatilization to intensify or triggering other chemical reactions. It should be stored separately from oxidants and acids, and must not be mixed. Because 2% 2C4-diethylaniline can cause violent reactions in contact with oxidants, and chemical reactions with acids may also occur, which may affect its quality and even cause danger. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials. If there is a leakage, it can be dealt with in time to prevent the spread of pollution.
Second, transportation. When transporting, it is necessary to ensure that the container does not leak, collapse, fall or damage. Because it is a liquid, if the container is damaged and leaks, it will not only cause material loss, but also may pollute the environment, and even cause harm to the health of transporters and surrounding people. The transportation process should be kept away from fire and heat sources. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. It is best to transport in the morning and evening in summer. Due to the high temperature in summer, it is easy to increase the pressure in the car due to excessive temperature during transportation at noon, which increases the risk factor. During transportation, it should be protected from sun exposure, rain and high temperature. During road transportation, it is necessary to follow the prescribed route and do not stop in residential areas and densely populated areas to reduce the possible harm to a large number of people in the event of an accident.