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2,4-Difluorobenzene-1-Thiol

2,4-Difluorobenzene-1-Thiol

Hongda Chemical

Specifications

HS Code

949669

Chemical Formula C6H4F2S
Molecular Weight 146.16
Appearance Typically a liquid or solid with a characteristic odor
Solubility In Water Insoluble (organic compound, low polarity)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone

As an accredited 2,4-Difluorobenzene-1-Thiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,4 - difluorobenzene - 1 - thiol packaged in a sealed, chemical - resistant bottle.
Storage 2,4 - difluorobenzene - 1 - thiol should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Due to its potential reactivity, store it separately from oxidizing agents and incompatible substances. This helps maintain its stability and reduces the risk of dangerous reactions.
Shipping 2,4 - difluorobenzene - 1 - thiol is shipped in specialized, tightly - sealed containers. These containers are designed to prevent leakage and exposure. Shipping follows strict regulations due to its chemical nature, ensuring safe transportation.
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2,4-Difluorobenzene-1-Thiol 2,4-Difluorobenzene-1-Thiol
General Information
Historical Development
"Historical Evolution of 2,4-Difluorothiophenol"
The study of chemical substances has always been an important matter in the academic community. The historical evolution of 2,4-difluorothiophenol is very meaningful. In the past, chemical inquiry was just emerging, and the understanding of various substances was still shallow. However, the research heart of the academic community has not been exhausted, and it has been unremitting exploration in the field of organic synthesis.
With the passage of time, science and technology have advanced day by day, instruments have gradually refined, and analytical methods have become more abundant. Scholars have gradually studied the structure and properties of 2,4-difluorothiophenol. At first, only part of its appearance was known, but after repeated experiments and studies, the wonder of its molecular structure and its characteristics in chemical reactions were understood. From ignorance to clarity, many ancestors worked hard to make the mystery of 2,4-difluorothiophenol gradually appear in front of the world, paving the way for subsequent application and expansion.
Product Overview
Today there is a substance called 2,4-Difluorobenzene-1-Thiol. This substance is unique. It is an organosulfur compound, on the benzene ring, with difluorine atoms and thiol groups. Appearance may be colorless to light yellow liquid, with a special smell.
In the chemical industry, it has a wide range of uses. It is often used as a key intermediate in organic synthesis, involved in the preparation of medical drugs and pesticides. In the creation of medicine, or as an important raw material for the development of specific drug molecules, to help adjust the activity of drugs and improve the efficacy. In the production of pesticides, it can participate in the synthesis of pharmaceuticals with high insecticidal and bactericidal properties, and protect the growth of agricultural products. Its chemical properties are active, and sulfhydryl groups can easily react with many reagents to form new chemical bonds and build complex organic structures, which add power to organic synthesis chemistry and have considerable application prospects.
Physical & Chemical Properties
2,4-Difluorobenzene-1-mercaptan is also an organic compound. Its physical and chemical properties are related to the properties and reactions of this substance. Looking at its physical properties, under normal temperature, it may have a specific color, taste and form. The genera of its boiling point and melting point are the inherent characteristics of the substance and are related to the transformation of its physical state. As for chemical properties, due to the presence of atoms such as fluorine and sulfur, it may have special activities. The high electronegativity of fluorine atoms changes the distribution of molecular electron clouds and affects its reaction with other substances. The existence of thiol groups also gives it unique chemical activities and can participate in a variety of chemical reactions, such as nucleophilic substitution, oxidation, etc. The physicochemical properties of this compound lay the foundation for in-depth understanding and application of this substance, and may be of important value in the fields of organic synthesis and materials science.
Technical Specifications & Labeling
Nowadays, there are chemical substances 2,4 - Difluorobenzene - 1 - Thiol, and our generation focuses on the process specifications and identification (product parameters). The process specifications of this substance need to clarify the purity of its ingredients, and the preparation method should follow strict procedures to ensure the same quality. Its identification (product parameters), such as properties, melting point, boiling point, solubility and other physical parameters, must be accurately identified. When preparing, the raw materials must be well selected, the reaction conditions must be carefully controlled, and the factors of temperature and pressure must not be slightly different. In this way, the high-quality 2,4-Difluorobenzene-1-Thiol can be obtained, which can play its due role in industrial applications, scientific research and exploration, and contribute to the development of chemistry.
Preparation Method
To prepare 2,4-Difluorobenzene-1-Thiol, first take an appropriate amount of 2,4-Difluorobenzene as raw material and place it in a reactor with thiourea. Dissolve it with an appropriate organic solvent, control the temperature in a specific range, and stir to fully react. After this reaction has gone through several times, pay attention to the change of temperature during this period, and do not let it exceed the limit.
After the reaction is completed, pour the product into a container containing an appropriate amount of lye, and convert it into a corresponding salt for separation. Then, adjust the pH value with a suitable acid solution to precipitate the target product. After many washing, filtering, drying and other processes, its impurities are removed to obtain pure 2,4-Difluorobenzene-1-Thiol.
In the preparation, the conditions of each reaction step, such as temperature, duration, material ratio, etc., must be precisely controlled. If the conditions are poor, the product may be impure or even the yield will be sharply reduced. At the same time, a complete monitoring mechanism should be established to ensure the smooth preparation process and the quality of the product.
Chemical Reactions & Modifications
There is now a chemical substance, named 2,4 - Difluorobenzene - 1 - Thiol. The reaction and modification of chemistry are the focus of our research.
To observe its reaction, it is necessary to explore its response to various reagents. The temperature and pressure of the environment are affected. To make it conform, or adjust the conditions, or add additives.
As for modification, it can increase its stability, change its solubility, and change its chemistability. Or introduce new radicals, adjust its structure, and hope to get better properties. If the ancient method is used, add a certain agent at a suitable temperature, follow a certain order, and hope that it will meet expectations and improve its performance. In the study of the reaction and modification of 2,4 - Difluorobenzene - 1 - Thiol, we should carefully investigate the results and contribute to chemistry.
Synonyms & Product Names
2,4-Difluorobenzene-1-mercaptan is also a chemical product. Its name is different, and there is quite a bit of existence. The name of the chemical thing may change depending on the use, place, and time.
In the past, the family of Fangjia used to have different names for this thing. Or according to its shape, or due to its production method, many different names have arisen. Although the names are different, they all refer to this 2,4-difluorobenzene-1-mercaptan.
The name of the merchant in the world also has the name of various commodities. Whether its name is easy to remember, or if you want to show its uniqueness, it is inseparable from the reality of this thing.
Although various synonyms and commodity names are diverse, they are all clear to the researcher. Only by knowing the truth can they be able to proceed unimpeded in the research path of chemistry and study the wonders of this 2,4-difluorobenzene-1-thiol.
Safety & Operational Standards
Specifications for safety and operation of 2,4-difluorobenzene-1-mercaptan
Fu 2,4-difluorobenzene-1-mercaptan is an important substance in chemical research. If you want to use this substance, you must first clarify its safety and operation specifications in order to ensure the smooth operation of the experiment and protect the health of the human body.
This substance has certain chemical activity. When storing, store it in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent danger caused by heat. The container must be tightly sealed to avoid excessive contact with air and moisture to avoid deterioration or reaction.
When operating, the experimenter needs to wear appropriate protective equipment. Wear protective clothing to protect against possible damage to the body; wear protective gloves to prevent direct contact with the skin; wear protective glasses to protect the eyes from accidental splashing.
When taking it, the movement should be stable and accurate. Cover the container tightly after use, and do not expose the substance to the air for too long. During the experiment, if you accidentally come into contact with this object on the skin, you should quickly rinse it with plenty of water, and seek medical treatment if necessary. If it splashes into the eye, you need to rinse it with plenty of water immediately and seek medical attention quickly.
Furthermore, ventilation of the experimental environment is essential. When an effective ventilation system is set up, volatile gases should be drained in time to avoid their accumulation in the air, causing poisoning or explosion risk.
The disposal of this waste should also follow strict regulations. It should not be discarded at will, but should be collected and treated according to the specified method to prevent pollution to the environment.
In short, in the research and use of 2,4-difluorobenzene-1-thiol, strict adherence to safety and operation standards is essential to ensure the safety and success of the experiment.
Application Area
2,4-Difluorobenzene-1-mercaptan has specific properties and is useful in various fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create special drugs to treat various diseases and eliminate diseases for the common people. In the genus of material science, it is also quite important, which can optimize the properties of materials, make them durable and unique, and apply them to high-tech materials. In the industry of fine chemicals, it can become high-quality raw materials, produce exquisite chemical products, and increase the quality and efficiency of products. All of these show that 2,4-difluorobenzene-1-mercaptan has great potential in the application field and has contributed to the progress of many industries.
Research & Development
Recently, I have studied 2,4-Difluorobenzene-1-Thiol. It has unique properties and has great potential in the field of organic synthesis.
Initial exploration revealed that its structure is exquisite, and the difluorine atom coexists with the thiol group, which affects each other, resulting in its unique reactivity. After various experiments, the effect of it with a variety of reagents was observed, and the law of its participation in the reaction was clear.
Currently, we are committed to expanding its application. We think of using it as a basis to create a new synthesis path and create novel compounds. Hope to use its characteristics to make materials with excellent functions, or in pharmaceutical research and development, to obtain ingredients with special effects.
Although the road to research has been difficult, I still believe that with time and careful research, I will be able to make significant progress in the research and development of this product, contributing to the development of chemistry.
Toxicity Research
Those who study poisons in modern times, focus on this substance at 2,4-Difluorobenzene-1-Thiol. Detailed observation of its toxicity is related to the health of living beings, and must be careful.
First study its chemical properties, unique structure, atomic compatibility. After various experiments, observe its changes in various media. Or dissolve water, or mix with organic agents, depending on its reaction, observe its decomposition.
Re-explore its impact on living things. Take insects, rodents, etc., as an experiment, and observe the symptoms after ingestion or exposure. See signs of movement disorders, physiological violations. What's more, endanger life, cause damage to organs, and dysfunction.
And think about its circulation in the environment. Or it seeps into the soil with water flow, or it rises in the atmosphere due to the wind. Fear of its accumulation in the ecology and harm to all things.
Therefore, the research on toxicity should not be discontinued. It is expected that its harm will lay the foundation for protection policies and governance laws to ensure the safety of all beings and the tranquility of the environment.
Future Prospects
I have tried to study chemical substances. Looking at 2,4 - Difluorobenzene - 1 - Thiol now, I feel that its development in the future is quite impressive.
This product has unique chemical properties and can be expanded in various fields. It is expected that it can be used in the development of medicine, or it can be a new path to cure diseases. With its characteristics, it may help to create special drugs to save patients from pain.
In the field of materials, it is also expected to emerge. Or it can participate in the production of new materials to make materials have better properties, such as strength and stability, to meet the needs of high-tech in the future.
And with the deepening of research and the improvement of craftsmanship, its productivity will increase, the cost will decrease, and it will be more widely used in the world, benefiting everyone. Although the road ahead may be difficult, we researchers must have strong ambitions, hoping that this product will shine in the future, develop endless possibilities, and become a new chapter of the times.
Where to Buy 2,4-Difluorobenzene-1-Thiol in China?
As a trusted 2,4-Difluorobenzene-1-Thiol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Difluorobenzene-1-Thiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluorobenzene-1-mercaptan?
2% 2C4-diethyl-1-naphthalenesulfonic acid is an important organic compound with a wide range of uses in the chemical industry. Its main uses are as follows:
First, it can be used as a dye intermediate. With its unique chemical structure, it can be converted into a variety of dyes with bright colors and excellent properties through a series of chemical reactions. These dyes are widely used in the textile, printing and dyeing industries to give fabrics rich colors, and have good color fastness and light resistance. For example, in silk printing and dyeing, dyes synthesized with this intermediate can make silk products colorful and long-lasting.
Second, it can be used as a surfactant raw material. After appropriate chemical modification, 2% 2C4-diethyl-1-naphthalenesulfonic acid can be converted into a surfactant with unique properties. Such surfactants play an important role in the daily chemical, paint, ink and other industries, which can reduce the surface tension of liquids and improve the properties of emulsification, dispersion and wetting. In detergents, it can improve the decontamination ability and foam stability.
Third, it is also used in the field of pharmaceutical synthesis. Due to its chemical activity and structural characteristics, it can be used as a key structural unit for the construction of complex drug molecules. By organic synthesis, it can be linked with other active groups to prepare drugs with specific pharmacological activities. In the synthesis of some drugs for the treatment of cardiovascular diseases, the 2% 2C4-diethyl-1-naphthalenesulfonic acid-derived structure helps to improve the efficacy and bioavailability of drugs.
Fourth, it has potential uses in organic synthesis catalysts. Partially based on 2% 2C4-diethyl-1-naphthalenesulfonic acid derivatives, it can be used as a high-efficiency organic synthesis catalyst to promote the smooth progress of many organic reactions, such as esterification reactions, alkylation reactions, etc. Such catalysts have high activity and selectivity, which can improve the yield and purity of the reaction and reduce the occurrence of side reactions.
What are the physical properties of 2,4-difluorobenzene-1-thiol?
2% 2C4-diethyl-1-naphthalenesulfonic acid, which is a common compound in the chemical industry. Its physical properties are unique and worth exploring.
Looking at its properties, under room temperature, it is mostly white to light yellow crystalline powder. This form is easy to store and transport, and it is easy to measure and use in many chemical reactions.
The melting point is about [X] ° C. As one of the key physical properties of a substance, the melting point is of great significance for identifying the compound and controlling the related reaction process. The melting point is established, and its purity can be determined. If the purity is high, the melting point is stable and close to the theoretical value; if it contains impurities, the melting point is often offset, or decreased, or the melting range is widened.
In addition to solubility, it can show a certain solubility in water. This property makes it very useful in the reaction of aqueous systems and preparation of preparations. At the same time, it also has good solubility in some organic solvents, such as ethanol and acetone. This property helps it participate in reactions in different chemical environments, or as a solute to prepare specific solutions for chemical analysis, material synthesis and many other fields.
In addition, the density of 2% 2C4-diethyl-1-naphthalene sulfonic acid is also an important physical property. Its density is about [X] g/cm ³, which affects its distribution and behavior in the mixed system, and needs to be considered in the process of chemical production, such as material ratio, reactor loading, etc.
In summary, the physical properties of 2% 2C4-diethyl-1-naphthalenesulfonic acid, including properties, melting point, solubility and density, play a decisive role in its application in chemical industry, materials, analysis and many other fields. In-depth understanding of these properties can better control this material and serve various production and scientific research activities.
Is the chemical properties of 2,4-difluorobenzene-1-thiol stable?
The chemical properties of 2% 2C4-diethyl-1-naphthalenesulfonic acid are relatively stable. In this compound, the sulfonic acid group (-SO-H) is connected to the naphthalene ring, and the naphthalene ring has a conjugated system, and the structure is relatively stable. Although the basic sulfonic acid has certain activity and can participate in many chemical reactions, under common environmental conditions, as long as no specific reaction conditions or reagents are encountered, the overall chemical properties of 2% 2C4-diethyl-1-naphthalenesulfonic acid are still stable.
In the general temperature and humidity environment, if there are no extreme chemical intervention reagents such as strong oxidants, strong acids, and strong bases, the compound will not spontaneously undergo significant chemical changes. However, it should be noted that the sulfonic acid group can neutralize with the base to form the corresponding sulfonate. At the same time, under specific catalysts and reaction conditions, the hydrogen atom or ethyl group on the naphthalene ring may also participate in the substitution reaction.
In short, 2% 2C4-diethyl-1-naphthalenesulfonic acid is relatively stable chemically under conventional conditions, but under specific chemical environments and reaction conditions, it will exhibit specific chemical reactivity.
What are the synthesis methods of 2,4-difluorobenzene-1-thiol?
The synthesis methods of 2% 2C4-diethyl-1-naphthalene sulfonic acid are as follows:
One is the sulfonation method. Select the refined 2,4-diethylnaphthalene, and add an appropriate amount of sulfonating reagents, such as concentrated sulfuric acid and fuming sulfuric acid, into a suitable reactor. The temperature is controlled within a certain range, usually ranging from tens of degrees Celsius to more than 100 degrees Celsius, and the reaction takes several hours. The sulfonic acid group of the sulfonating reagent can be substituted with a specific position of the naphthalene ring to obtain 2,4-diethyl-1-naphthalene sulfonic acid. This process requires careful observation of the reaction temperature and the amount of reagent to prevent side reactions such as excessive sulfonation.
Diethylnaphthalene acylation-reduction method. First, 2,4-diethylnaphthalene is acylated with a suitable acylating reagent, such as acyl halide or acid anhydride, under the action of a catalyst. Commonly used catalysts include Lewis acids, such as aluminum trichloride. The acylation reaction can connect the acyl group to the naphthalene ring. Then, through the reduction step, the acyl group is converted into a sulfonic acid group. This path step is slightly complicated, but it can effectively control the substitution position and improve the purity of the product.
The third is the halogenation-sulfonation method. First, 2,4-diethylnaphthalene is reacted with the halogenation reagent to introduce a halogen atom into the naphthalene ring. Commonly used halogenation reagents include halogen elements or hydrogen halides. After the halogenation reaction is completed, it reacts with sulfur-containing reagents to replace the sulfonic acid group with a halogen atom to obtain the target product. This method requires precise control of the halogenation and sulfonation conditions to ensure that the reaction proceeds in the expected direction.
All synthesis methods have advantages and disadvantages. In practical applications, the appropriate method should be weighed according to the availability of raw materials, cost, product purity requirements and many other factors.
What are the precautions for storing and transporting 2,4-difluorobenzene-1-thiol?
2% 2C4-diethyl-1-naphthalenesulfonic acid has many precautions during storage and transportation. This substance is corrosive to a certain extent. When storing, be sure to choose a suitable container. Corrosion-resistant materials, such as special plastic drums or metal containers lined with anti-corrosion coatings, should be used to prevent corrosion of the container and material leakage.
The storage environment is also extremely critical. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to heat or open flames, it may cause danger, such as combustion or even explosion. At the same time, avoid mixing with oxidizers, alkalis and other substances to prevent chemical reactions that can change the properties of the substance or produce dangerous products.
In terms of transportation, transportation vehicles need to take protective measures. Ensure the tightness of the vehicle to prevent material leakage due to bumps, vibrations and other factors during transportation. Transportation personnel also need to undergo professional training to be familiar with the characteristics of the substance and emergency treatment methods. During transportation, pay close attention to the condition of the goods. If any abnormalities such as leakage are detected, effective measures should be taken immediately to deal with it.
The loading and unloading process cannot be ignored. Care should be taken during operation to avoid brutal loading and unloading to prevent damage to the packaging. Once the packaging is damaged, it will not only lead to material loss, but also may cause safety problems due to contact with the external environment.
In addition, whether it is storage or transportation, relevant safety regulations and operating procedures should be strictly followed, and safety signs and warnings should be made so that relevant personnel can quickly identify the danger, so as to take correct measures to ensure the safety of the entire storage and transportation process.