As a leading 2,4-Difluoro-N-[2-(Methyloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Pyridinyl]Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2,4-difluoro-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide?
This is about the chemical structure of 2,4-diene-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide.
To clarify its chemical structure, when analyzing the functional groups from each part. "2,4-diene" indicates that this compound contains two carbon-carbon double bonds, and the double bond positions are at the 2nd and 4th positions. " N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] "In this section," N - "shows that the structure is connected by a nitrogen atom. Among them, "2 - (methoxy) " means that there is a methoxy group (- OCH 😉) attached to a structure at position 2; "5 - (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclic pentane-2-yl) " means connecting a 1,3,2-dioxyboron heterocyclic pentane structure modified by 4 methyl groups at position 5, which contains boron, oxygen and other atoms to form a ring; "3-pyridyl" indicates the presence of a pyridine ring, and the connection check point is at position 3 of the pyridine ring. And "benzenesulfonamide" indicates that there is a benzene ring connected to the sulfonamide group (- SO 2O NH 2O).
Overall, this compound uses benzenesulfonamide as the basic skeleton, and has a diene structure at the 2,4 positions of the benzene ring. A substituent containing methoxy, specific boron heterocyclopentane and pyridyl groups is connected by nitrogen atoms. This structure endows the compound with unique chemical properties and reactivity, and may have important uses in organic synthesis, pharmaceutical chemistry and other fields.
What are the main uses of 2,4-difluoro-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide?
2% 2C4-diene-N- [2- (methoxy) -5- (4% 2C4% 2C5% 2C5-tetramethyl-1% 2C3% 2C2-dioxyboron heterocyclopentaborane-2-yl) -3-pyridyl] benzamide, this is an organic compound. Looking at the structure of this compound, its application may involve the fields of medicinal chemistry, materials science, etc.
In the field of medicinal chemistry, or can be used as a potential drug molecule. Its pyridyl and benzamide structural parts are often found in drug design, and can be combined with specific biological targets, such as protein receptors, enzymes, etc., or have the ability to regulate biological activity, in order to achieve the purpose of treating diseases. For example, some anticancer drugs contain structures similar to benzamide, which can inhibit the activity of cancer cell proliferation-related proteins.
In the field of materials science, 4% 2C4% 2C5% 2C5-tetramethyl-1% 2C3% 2C2-dioxoborane structure or endow the material with unique electrical and optical properties. Boron heterocyclopentylborane structures are often used in organic optoelectronic materials, such as organic Light Emitting Diode (OLED) and organic solar cell materials, which can adjust the energy level structure of the material, improve the charge transfer efficiency and luminescence performance.
In summary, this compound may have important uses in medicine, materials and other fields, but the exact application still depends on further experiments and research to determine.
What are the synthesis methods of 2,4-difluoro-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide?
The synthesis method of 2% 2C4-diene-N - [2 - (methoxy) -5 - (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentylborane-2-yl) -3 -pyridyl] benzenesulfonamide allows me to explain in detail.
To synthesize this product, the commonly used method is the coupling reaction catalyzed by transition metals. Among them, the coupling reaction of Suzuki is quite suitable.
First, take an appropriate halogenated aromatic hydrocarbon, such as a 2,4-dienylbenzenesulfonamide derivative containing a halogen atom, and combine it with a boron-containing reagent, namely 2- (methoxy) -5 - (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentaborane-2-yl) -3-pyridyl boronic acid or its esters, in an organic solvent. Common organic solvents, such as toluene, dioxane, N, N-dimethylformamide, etc., can be used.
Then, add an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, potassium phosphate, etc. The function of alkali is to promote the reaction and adjust the pH of the reaction system.
In addition, introduce transition metal catalysts, such as tetra (triphenylphosphine) palladium (0) and other palladium catalysts. This catalyst is like a helmsman of a chemical reaction, guiding the direction of the reaction and accelerating the reaction rate.
When reacting, the reaction temperature and time need to be strictly controlled. Generally speaking, the temperature is controlled within an appropriate range, such as 80-120 ° C, and the reaction time depends on the specific situation. It may take several hours or even ten hours to ensure that the reaction is fully carried out.
After the reaction is completed, the product needs to be separated and purified. Column chromatography can be used to separate the product from the reaction mixture with a suitable eluent to obtain a pure 2% 2C4-diene-N- [2- (methoxy) -5 - (4,4,5,5-tetramethyl-1,3,2-dioxoboronyl heterocyclopentylborane-2-yl) -3-pyridyl] benzenesulfonamide.
In addition, other synthesis paths can be explored, such as by gradually building a molecular skeleton, synthesizing key intermediates first, and then linking them through further reactions to form the target product. However, regardless of the method, it is necessary to carefully operate and strictly control the reaction conditions in order to improve the yield and purity of the product.
What are the physical and chemical properties of 2,4-difluoro-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide?
2% 2C4-diethyl-N - [2 - (methoxy) -5 - (4,4,5,5-tetramethyl-1,3,2-dioxane-2-yl) -3-pyridyl] benzenesulfonamide, an organic compound. Looking at its structure, the skeleton containing benzenesulfonamide, this structure is common in many drugs and bioactive molecules, endowing the compound with diverse physical and biological properties.
In terms of physical properties, its molecules have a certain polarity due to their polar sulfonamide groups and methoxy groups, and may have good solubility in polar solvents, which is conducive to transportation and distribution in biological systems. At the same time, the structural part of tetramethyl-1,3,2-dioxane can affect the overall spatial configuration and stability of the molecule, or cause its melting point, boiling point and other physical parameters to have unique manifestations.
In terms of chemical properties, sulfonamide groups have certain reactive sulfur-nitrogen bonds, which can participate in a variety of chemical reactions, such as substitution reactions with nucleophiles, and then derive more multi-functional products. The oxygen atom of methoxy groups has solitary pair electrons, which can participate in chemical reactions as electron donors, affect the electron cloud density of the benzene ring, and make the adjacent para-position of the benzene ring more prone to electrophilic substitution reactions. Pyridinium groups, as electron-rich aromatic heterocycles, can also participate in various reactions such as electrophilic and nucleophilic, which greatly enriches the chemical transformation pathways of this compound. In addition, dioxapentaborane is often used as a protecting group or participates in boration reactions in organic synthesis, providing various strategies for the synthesis and modification of this compound.
What are the market prospects for 2,4-difluoro-N- [2- (methoxy) -5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) -3-pyridyl] benzenesulfonamide?
Guanfu 2,4-diene-N - [2 - (methoxy) -5 - (4,4,5,5-tetramethyl-1,3,2-dioxyboron-heterocyclopentylborane-2-yl) -3 -pyridyl] benzothiazole is in the market, and its prospects can be seen.
This compound may have extraordinary potential in the field of pharmaceutical research and development. The structure of Gainpyridyl and benzothiazole is often biologically active. The addition of methoxy group may change its fat solubility and increase its cell penetration power, which is beneficial for drug delivery. Tetramethyl-1,3,2-dioxyboron-heterocyclopentylborane-2-yl, or involves coupling reactions, can be extended to synthetic chemistry in order to build the path of complex molecular structures.
In the context of materials science, there are also opportunities. The conjugated structure of benzothiazole may give it unique photoelectric properties, such as the genus of fluorescence emission. Diene structure, or related to polymerization, can make polymer materials with special functions, used in optoelectronic devices, sensors, etc.
However, it also faces challenges. The synthetic path may need to be carefully designed to achieve high efficiency and high yield. And the metabolic pathway and toxicity in living organisms remain to be studied in detail. Only by making this clear can we make good use of its strengths, avoid its weaknesses, and promote it to shine in the market, contributing to the advancement of medicine and materials.