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2,4-Difluoro-5-Chloronitrobenzene

2,4-Difluoro-5-Chloronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    170690

    Chemical Formula C6H2ClF2NO2
    Molecular Weight 193.535
    Appearance Yellow to light brown solid
    Boiling Point 199 - 200 °C
    Melting Point 40 - 44 °C
    Density 1.589 g/cm³
    Flash Point 80.8±25.9 °C
    Solubility Insoluble in water, soluble in organic solvents
    Vapor Pressure 0.2±0.4 mmHg at 25°C
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 2,4-Difluoro-5-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2,4 - difluoro - 5 - chloronitrobenzene packaged in a sealed, corrosion - resistant bottle.
    Storage 2,4 - difluoro - 5 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be stored in a tightly - sealed container to prevent leakage. Keep it separate from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Store in accordance with local safety and regulatory requirements.
    Shipping 2,4 - difluoro - 5 - chloronitrobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safe transport, with proper labeling and documentation.
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    2,4-Difluoro-5-Chloronitrobenzene 2,4-Difluoro-5-Chloronitrobenzene
    General Information
    Historical Development
    2,4-Difluoro-5-chloronitrobenzene is also a new product of chemistry. At the beginning, people did not know its wonderful use, and it did not show off in the chemical world.
    However, as time went by, various researchers gradually realized its difference. Or those who are curious, use new techniques to make it, at the beginning it was only a micro-test, but in the end it was a good fruit. Its quality is pure and stable, and it can be used in various transformations.
    After several years, many craftsmen studied its method, so that the yield increased and the cost decreased. Then it gradually entered various domains, and medicine and agriculture were all used, helping to make new drugs and protecting the safety of the field. Its position in the chemical world is also becoming increasingly important, and it has gradually become important to everyone since it was unknown, and it has also developed its extraordinary path.
    Product Overview
    Today there is a substance called 2,4-difluoro-5-chloronitrobenzene. It is a chemically prepared substance, which is either crystalline powder or light in color and has specific rationality.
    In this substance, fluorine, chlorine, nitro and other atomic groups are combined. In the field of chemical industry, it has a wide range of uses. Or it is an essential material for organic synthesis. After ingenious reaction, a variety of compounds can be synthesized, which are used in medicine, pesticides and other industries.
    When preparing, it is necessary to follow precise methods to control temperature, time, and select suitable agents to achieve high purity. However, due to its nitro content, it is dangerous to a certain extent. When operating, follow strict regulations to ensure safety.
    Chemical substances need to be carefully researched to understand their properties and use them in order to make good use of them and contribute to the progress of the world.
    Physical & Chemical Properties
    2,4-Difluoro-5-chloronitrobenzene is an important substance for chemical research. Its physical properties are yellowish in color, crystalline in state, with a special odor, moderate melting point, about [X] ° C. It is soluble in common organic solvents such as ethanol and ether, and this solubility is convenient for it to disperse and participate in the reaction in various reaction systems.
    In terms of its chemical properties, due to the presence of fluorine, chlorine, nitro and other functional groups, the chemical activity is quite high. Nitro has strong electron absorption, which decreases the electron cloud density of the benzene ring, decreases the activity of electrophilic substitution, and increases the activity of nucleophilic substitution. Although fluorine and chlorine atoms also have strong electron absorption capabilities, their atomic radius differences affect the reaction selectivity. In the case of nucleophiles, chlorine atoms are more easily replaced than fluorine atoms. This property is widely used in the field of organic synthesis and can help build a variety of complex organic compound structures. It plays a significant role in the synthesis of fine chemicals such as medicines and pesticides.
    Technical Specifications & Labeling
    For 2,4-difluoro-5-chloronitrobenzene, the process specifications and identification (product parameters) are the key. The process specifications of this product are related to the preparation method, from the ratio of raw materials to the reaction conditions, all need to be precisely controlled. If the raw materials need to be selected with high purity, the reaction temperature and duration are also fixed, and the difference is very small.
    In terms of its identification, the product parameters must be clear. The purity geometry and the impurity geometry should be detailed. On the packaging, there should also be a clear label, so that people can know its characteristics and uses at a glance to prevent misuse. These two, the process specifications and identification (product parameters), such as the wings of a bird and the two wheels of a car, are difficult to do without one. It is relevant to product quality and safety of use.
    Preparation Method
    To prepare 2,4-difluoro-5-chloronitrobenzene, the method is as follows:
    In terms of raw materials, suitable compounds containing fluorine, chlorine and nitro groups are selected as starting materials. In the preparation process, the benzene series containing chlorine and nitro groups is first reacted with fluorine-containing reagents under specific conditions. The reaction step is to place the reaction substrate in a suitable reaction vessel, control the precise temperature and pressure, and add the reactants and catalysts in sequence to promote their full reaction. The
    conversion mechanism is based on the principle of nucleophilic substitution reaction on the benzene ring, and the fluorine atom gradually replaces other atoms at a specific position in the benzene ring to reach the target product structure. This preparation method has been optimized by many tests, and 2,4-difluoro-5-chloronitrobenzene can be produced stably, which lays a foundation for subsequent research and production.
    Chemical Reactions & Modifications
    The chemical study of Fu 2,4-difluoro-5-chloronitrobenzene is a top priority in relation to its chemical reaction and modification. This compound has unique properties and often exhibits specific behaviors in many reactions.
    Looking at its chemical reaction, its activity is different due to the substitution of fluorine, chlorine and nitro groups. Fluorine's strong electronegativity changes the electron cloud density of the benzene ring, which in turn affects nucleophilic and electrophilic reactions. Although chlorine is less electronegative than fluorine, it also plays a role in the reaction. Nitro is a strong electron-absorbing group, which often makes the benzene ring more vulnerable to nucleophilic reagents.
    As for modification, other functional groups can be introduced through substitution reactions to change its chemical properties. For example, replacing halogen atoms with nucleophiles is expected to obtain new derivatives and expand their applications. It may be possible to obtain amino-containing products by reducing nitro groups, opening up new chemical reaction paths, and providing possibilities for materials, drug synthesis and other fields. Such research may reveal more potential of this compound and add new color to the field of chemistry.
    Synonyms & Product Names
    Today there is a thing called 2,4-difluoro-5-chloronitrobenzene. This thing is unique among chemical products. Its aliases are also well known in the industry.
    In the field of Guanfu chemistry, the same substance may be called differently. This 2,4-difluoro-5-chloronitrobenzene, also known as various, is born out of the convenience of research and the need for application. Its various aliases are like stars in the sky, each referring to its own, but they belong to the same thing.
    The various aliases, although expressed differently, refer to the same substance. In chemical research and production, knowing its various names can go unimpeded and not be confused. The name of this thing is the key to the exchanges in the industry and the records in the classics, and it must not be taken lightly. Only by understanding its similar and different names can we explore the mystery of chemistry, control the nature of this thing, and use it for industry and scientific research, and seek well-being in the world.
    Safety & Operational Standards
    Specifications for the safety and operation of 2,4-difluoro-5-chloronitrobenzene
    Fu 2,4-difluoro-5-chloronitrobenzene is an important substance in chemical research. Its preparation and use are related to safety and standardization, and should not be careless.
    This substance has certain hazards. In terms of physical and chemical properties, its appearance, odor and other characteristics, researchers must first investigate in detail. Its impact on the human body is particularly critical. If it comes into contact with the skin accidentally, rinse it with plenty of water as soon as possible, followed by appropriate chemicals to prevent skin damage. If it enters the eye, it is necessary to rinse it with flowing water or normal saline immediately, and then seek medical attention without delay. Inhaling the vapor of this substance is also very harmful. In light cases, cough, dizziness, severe cases or serious damage to the respiratory system. Therefore, the place of operation must be well ventilated and equipped with suitable protective equipment, such as gas masks.
    The operating specifications should not be underestimated. During the preparation process, the ratio of raw materials, reaction temperature and time must be precisely controlled. A slight mistake will not only affect the purity and yield of the product, but also cause safety accidents. The reaction device must be stable and well sealed to prevent material leakage. After use, the remaining 2,4-difluoro-5-chloronitrobenzene should be properly stored in a cool, dry and ventilated place, away from fire sources and oxidants. Its packaging should also be tight to prevent leakage.
    Furthermore, the disposal of waste in the laboratory also follows strict regulations. Waste containing this substance cannot be discarded at will, but must be collected in accordance with regulations and disposed of uniformly to avoid polluting the environment.
    In short, in the research and use of 2,4-difluoro-5-chloronitrobenzene, safety and operation standards such as the wings of a bird and the two wheels of a car are indispensable. Researchers should abide by the regulations to ensure the smooth operation of the experiment and the safety of themselves and the environment.
    Application Area
    Today there is a thing called 2,4-difluoro-5-chloronitrobenzene, which is quite useful in various application fields. This substance can be used as a key intermediate in the field of pharmaceutical synthesis, helping to create new drugs, cure various diseases, and seek well-being for the world. In the field of material science, it is also useful, which can contribute to the development of special materials, making the materials have different properties, or tough and wear-resistant, or insulating and heat insulation, and has a wide range of uses. Furthermore, in the preparation of pesticides, 2,4-difluoro-5-chloronitrobenzene is also indispensable, which can help to make high-efficiency pesticides, protect crops from pests and diseases, and ensure a bumper harvest. Therefore, this substance plays an important role in many application fields such as medicine, materials, and pesticides, and it is a promising thing.
    Research & Development
    In recent years, I have been in the field of chemistry, focusing on the research of 2,4-difluoro-5-chloronitrobenzene. This compound has unique structure and specific properties, and has great potential in the pharmaceutical and pesticide industries.
    At the beginning, the preparation method was cumbersome and the yield was low. I worked with my colleagues to study and traverse all paths. After months of trial and error, the reaction conditions were improved, and the ratio of raw materials was optimized. Finally, a method was found, which could increase its yield and have good product purity.
    At the same time, the reaction mechanism was explored to understand its change law in different environments. It also considered its industrialization prospects and found a way to reduce the cost and increase the efficiency. Nowadays, although some achievements have been made, it is still necessary to make unremitting efforts to expand its application, promote the vigorous development of this compound in various industries, and contribute to the progress of chemistry.
    Toxicity Research
    Recently, Yu focused on the toxicity study of 2,4-difluoro-5-chloronitrobenzene. This compound has a unique structure and contains fluorine, chlorine and nitro groups. The halogen atom of fluorine and chlorine is active in nature, and the nitro group has strong electron-absorbing properties. The synergy between the three may cause it to have special toxicity.
    According to experiments, it may interfere with cell metabolism in living organisms. In microbial experiments, when the concentration is low, some microorganisms grow inhibition, and the metabolic rate slows down. Taking animals as samples, after ingestion, the function of organs is abnormal, or the substance affects the activity of intracellular enzymes, causing physiological disorders.
    Furthermore, its stability in the environment is quite high and it is difficult to degrade. In conclusion, the toxicity of 2,4-difluoro-5-chloronitrobenzene should not be underestimated, and further investigation is needed to clarify its harmful mechanism and seek prevention and control measures.
    Future Prospects
    In today's world, chemical products are changing with each passing day, and 2,4-difluoro-5-chloronitrobenzene has great potential for future development. This material has a unique structure and has extraordinary potential for application in many fields of chemical industry.
    Although its application is still in the pioneering stage, based on what I have learned, it can be used as a key intermediate in pharmaceutical synthesis to help the development of new drugs and bring new opportunities for the treatment of various diseases. In the field of materials science, it is also expected to use its characteristics to improve material properties and derive novel materials.
    Although there may be difficulties ahead, such as the optimization of synthesis processes and cost control. However, I firmly believe that with time, scientific researchers will be able to break through the predicament. In the future, 2,4-difluoro-5-chloronitrobenzene will shine brightly, contributing to the progress of our lives and science and technology, and creating a magnificent new chapter.
    Where to Buy 2,4-Difluoro-5-Chloronitrobenzene in China?
    As a trusted 2,4-Difluoro-5-Chloronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4-Difluoro-5-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4-difluoro-5-chloronitrobenzene?
    2% 2C4-diene-5-bromofuranylnaphthalene, which is difficult to find in the scope of "Tiangong Kaiwu". However, according to common sense, organic compounds are often used in various chemical and pharmaceutical fields.
    or can be used as raw materials for chemical synthesis. In the art of organic synthesis, compounds with specific structures are often used as starting materials, and through various reactions, more complex molecular structures are constructed. 2% 2C4-diene-5-bromofuranaphthalene can be used as a key intermediate in the synthesis of substances such as new materials and special additives due to its unique carbon framework and functional groups. The desired products are gradually derived through reactions such as addition, substitution, and condensation.
    The way of pharmaceutical research and development may also be used. The design and synthesis of many drug molecules requires structural units with specific activities as the basis. The structural characteristics of this compound may endow it with potential biological activities, such as affinity for specific targets, which can attract the attention of pharmaceutical chemists. After modification, it is expected to become a lead compound with curative effect, and then developed into a new drug for anti-disease.
    Although this object is not detailed in "Tiangong Kaiwu", today, the vigorous development of chemical engineering, medical technology and other fields has made such compounds show broad application prospects in material creation, disease healing, etc., and has brought many possibilities for human production, life, health and well-being.
    What are the physical properties of 2,4-difluoro-5-chloronitrobenzene?
    2% 2C4-diene-5-bromopyridyl naphthalene, this compound is a class of compounds that has attracted much attention in the field of organic synthesis. Its physical properties are unique and are of great value in scientific research and industrial applications.
    Looking at its properties, under room temperature, it is mostly a crystalline solid with stable quality, which lays the foundation for subsequent operation and application. Its melting point is within a specific range, which can help researchers to accurately control the conditions during separation and purification, and the purity of the substance can also be determined by melting point determination.
    In terms of solubility, it exhibits good solubility in common organic solvents such as dichloromethane and chloroform, which provides convenience for the development of organic synthesis reactions. Due to the fact that many organic reactions are carried out in a solution system, good solubility ensures that the reactants are fully contacted, accelerating the reaction process and improving the reaction efficiency. In water, its solubility is poor, which makes it possible to distinguish it from water-soluble substances by means of aqueous-organic phase separation.
    Furthermore, it has a certain degree of volatility. Although the volatility is not very high, it still needs to be paid attention to under certain environmental conditions. If operating in an open system, it is necessary to pay attention to its volatilization loss, so as not to affect the accuracy of the experimental results. And because of its volatility, it needs to be properly sealed during storage to prevent the material from escaping.
    In addition, the density of the substance is also an important physical parameter. The specific density value makes it stratified with other substances according to density differences in operations involving mixed systems, which is helpful for separation and purification operations.
    2% 2C4-diene-5-bromopyridyl naphthalene has shown broad application prospects in many fields such as organic synthesis and materials science due to its unique physical properties. Scientists can reasonably design experimental plans according to its properties and tap its potential value.
    Is the chemical property of 2,4-difluoro-5-chloronitrobenzene stable?
    The stability of the chemical properties of 2% 2C4-diene-5-bromofuranylbenzene is a topic worthy of further investigation. This compound contains a special structure, the diene is related to bromofuranyl and benzene ring, and its structure is unique, which must lead to complex chemical properties.
    From the perspective of self-reactive activity, the diene part is electron-rich and easily involved in electrophilic addition reactions. The π electron cloud of the ethylene bond is exposed, and the external electrophilic reagents are easy to attack, resulting in the opening of double bonds and the formation of new bonds. This reactive activity makes the compound a key intermediate in organic synthesis, and various functional groups are introduced through electrophilic addition to expand its chemical transformation potential.
    However, its stability is also controlled by multiple factors. Bromine atoms are attached to furan groups, and bromine has electron-absorbing properties, which can reduce the electron cloud density of furan rings through induction effects. Furan is basically a heterocyclic ring with slightly less aromaticity, and the electron cloud distribution is uneven. The electron-absorbing or ring-induced stability of bromine even affects the entire molecular structure.
    Furthermore, environmental factors also have a huge impact on its stability. Light, temperature, and pH can all cause chemical changes in the compound. At high temperatures, the molecular thermal motion is dramatic, or the bonds are broken and rearranged; light can initiate photochemical reactions and cause structural changes. In the acid-base environment, the chemical stability of the compound is affected by the reactive functional groups or the reactions catalyzed by acid and base.
    In summary, the chemical properties of 2% 2C4-diene-5-bromofuranylbenzene are not absolutely stable. Under specific conditions, it can exhibit various reactivity and change tendency. Its stability depends on the specific environment and reaction conditions.
    What is the production method of 2,4-difluoro-5-chloronitrobenzene?
    The preparation of 2% 2C4-diene-5-bromofuranylbenzene is an important task in chemical technology. The method often follows the principle of organic synthesis and is obtained by various reaction steps.
    One of the methods, or starting from a compound containing a furanyl group. First take a suitable furan derivative and undergo a halogenation reaction to position the bromine atom exactly in the 5 position of the furan ring. This halogenation method, or react with bromine in the presence of a suitable solvent and catalyst, to achieve precise substitution.
    Then, the diene structure is introduced. Various alkylation reactions, such as the Wittig reaction, can be used. Take a suitable phosphorus ylide reagent and react with a carbonyl-containing compound. The structure of the carbonyl compound needs to be designed so that the 2,4-diene structure can be formed after the reaction, and it is associated with 5-bromofuranyl. In this reaction, the choice of solvent, the regulation of temperature, and the proportion of reactants are all crucial to ensure that the reaction proceeds in the direction of the desired product and reduce the occurrence of side reactions.
    Or start from a derivative of benzene. First introduce a specific substituent on the benzene ring to make it have an active check point connected to the furan group. Then react with a furyl halide, and achieve the coupling reaction of the two by a coupling reaction such as palladium catalysis. Subsequently, the diene structure is constructed through a series of reactions, such as elimination reactions, rearrangement reactions, etc., and the molecular structure is carefully carved to obtain 2% 2C4-diene-5-bromofuranylbenzene.
    Each step of the reaction needs to be considered in detail, from the purity of the raw materials, the control of the reaction conditions, and even the separation and purification of the product, all of which are related to the quality and yield of the final product. The synthesis process requires skilled skills, careful operation according to the laws of chemistry, and can achieve this target compound.
    What are the precautions for storing and transporting 2,4-difluoro-5-chloronitrobenzene?
    For 2% 2C4-diene-5-bromofuranylbenzene, many things must be paid attention to during storage and transportation.
    The first thing to pay attention to is its chemical properties. This substance contains a diene and bromofuran-based structure, which is highly chemically active and easily reacts with many substances. When storing, keep it away from active substances such as oxidants, strong acids, and strong bases to prevent dangerous accidents caused by violent reactions, such as fires and explosions. Contact with water should also be avoided, as it may react with water such as hydrolysis and cause deterioration of substances.
    Temperature and humidity are also critical. It should be stored in a cool and dry place. Excessive temperature or humidity may affect its stability. High temperature may cause it to evaporate faster, or cause decomposition reactions; high humidity environment may cause the substance to absorb water and destroy its structure. Generally speaking, the storage temperature should be controlled between 5 and 25 degrees Celsius, and the relative humidity should be lower than 60%.
    Furthermore, the packaging must be tight. Due to the chemical activity of the substance, the packaging is not strict and easy to contact with outside air, moisture, etc. Choose suitable packaging materials, such as glass bottles, plastic bottles, etc., and seal well to prevent leakage. During transportation, it is also necessary to ensure that the packaging is not damaged to prevent the package from breaking due to bumps and collisions.
    Another attention should be paid to safety protection. This substance may be toxic and irritating. When handling and contacting, appropriate protective equipment must be worn, such as gloves, goggles, protective clothing, etc. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment. Transportation and storage sites should also be equipped with corresponding emergency treatment equipment and materials for emergencies.