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2,4-Difluoro-5-Chloro-1-Nitrobenzene

2,4-Difluoro-5-Chloro-1-Nitrobenzene

Hongda Chemical

Specifications

HS Code

683249

Chemical Formula C6H2ClF2NO2
Molar Mass 193.54 g/mol
Appearance Solid (likely yellowish)
Physical State At Stp Solid
Solubility In Water Low (non - polar aromatic compound with polar groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low at room temperature (due to its solid state and relatively high molecular weight)

As an accredited 2,4-Difluoro-5-Chloro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,4 - difluoro - 5 - chloro - 1 - nitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 2,4 - difluoro - 5 - chloro - 1 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizers and reducing agents. Store in a tightly - sealed container to prevent leakage and exposure to air or moisture, which could potentially affect its stability.
Shipping 2,4 - difluoro - 5 - chloro - 1 - nitrobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous material regulations, ensuring proper handling, storage, and transport to prevent leakage and environmental risks.
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2,4-Difluoro-5-Chloro-1-Nitrobenzene 2,4-Difluoro-5-Chloro-1-Nitrobenzene
General Information
Historical Development
2,4-Difluoro-5-chloro-1-nitrobenzene is also an organic compound. Tracing back to its source, at the beginning, many chemists have been unremitting in their exploration of various compounds. In the past, all the sages used their outstanding wisdom to study the principles of chemistry, and began to pay attention to such fluorine, chlorine, and nitro-containing benzene series.
At that time, the technology was not as developed as it is today, but the research heart of the public was as firm as a rock. After years of hard work and repeated trials, the method of synthesis has gradually become clear. The initial or difficult abnormality, the yield is low, but the unremitting improvement, the synthesis method is more refined. Therefore, 2,4-difluoro-5-chloro-1-nitrobenzene has gradually become a useful material in the chemical industry since it was a microorganism in the laboratory. In the organic synthesis industry, it has gradually become more and more important, opening a new chapter. Later generations also rely on the work of predecessors. To obtain this compound and use it, its development process depends on the hard work and wisdom of all scholars.
Product Overview
Nowadays, there is a substance called 2,4-difluoro-5-chloro-1-nitrobenzene. It is an organic compound in the form of crystalline state and has a light yellow color. This substance is widely used in the chemical industry and is an important raw material for the synthesis of many fine chemicals.
The preparation method often needs to be prepared by specific halogenation, nitrification and other reactions. During the reaction, various conditions such as temperature and proportion of reactants need to be carefully controlled to ensure the purity and yield of the product.
2,4-difluoro-5-chloro-1-nitrobenzene has certain chemical activity, the nitro group can be reduced, and the halogen atom can participate in the substitution reaction, whereby a variety of compounds can be derived, which have potential application value in the fields of medicine, pesticides, materials, etc. However, it also needs to be properly stored and used, because it may have certain toxicity and danger.
Physical & Chemical Properties
Today there is a substance called 2,4-difluoro-5-chloro-1-nitrobenzene. Its color may be light yellow, and if it is crystalline, it will be stable and self-sustaining under room temperature and pressure. In terms of its physical properties, the melting point is about a certain value, which is the key to determining its state. The boiling point also has a fixed number, which is related to its gas-liquid phase transition.
As for its chemical properties, because it contains nitro groups, it has the ability to oxidize and may change when it encounters a reducing agent. The presence of fluorine and chlorine atoms changes the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is different. It may be co-heated with alkali to produce different products; or it may meet with nucleophiles and form a novel structure. This is all due to its own physical and chemical properties. It is widely used in chemical, pharmaceutical and other industries. It is up to our generation to explore in detail to understand more of its mysteries.
Technical Specifications & Labeling
Today there is a product called 2,4-difluoro-5-chloro-1-nitrobenzene. In the investigation of process specifications and identification (product parameters), and even important matters.
Looking at this substance, in order to clarify its process specifications, it is necessary to carefully observe the preparation method. From the selection of raw materials, it must be pure and compatible according to a specific order. When reacting, temperature and pressure are the key, and precise control is required to obtain good products. The reaction time should not be ignored, and it should be stopped at the right time to ensure the quality of the product.
As for the identification (product parameters), when it is clear its materialization. Such as melting point, boiling point geometry, and solubility, this is a must-know for users. In addition, its purity label must be accurately measured, marked on the packaging, and displayed to everyone. In this way, the product can be properly applied, and the process specifications and labels are clear, which is the foundation of quality.
Preparation Method
The method of preparing 2,4-difluoro-5-chloro-1-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from fluoride, chloride and nitrogenation reagents because of their activity and adaptability.
At the beginning of the production process, fluoride and chloride are mixed in a specific solvent, the temperature is controlled to an appropriate extent, and a catalyst is used to promote the reaction. After the initial reaction is completed, add the nitrogenation reagent and continue to heat up. In this case, the reaction steps are orderly, first halogenation, and then nitrogenation to achieve precise synthesis.
The catalytic mechanism is also critical, and the catalyst used can reduce the reaction energy barrier and increase the reaction rate. The yield of 2,4-difluoro-5-chloro-1-nitrobenzene can be optimized by precisely adjusting the proportion of raw materials and strictly controlling the reaction temperature and duration.
Chemical Reactions & Modifications
Taste the technology of chemical industry, the mysteries are endless, and the transformation of substances follows its principles. Today there is a product, named 2,4 - Difluoro - 5 - Chloro - 1 - Nitrobenzene, which is very important in chemical research.
Its chemical reaction requires a detailed investigation of its mechanism. Every step change is related to the ratio of raw materials and the conditions of the reaction. Temperature, pressure, and catalyst are all key factors. A little difference, the results are very different.
As for its modification, it is to optimize the performance. Or enhance the stability, or increase the activity, to suit different needs. The way to modify lies in the delicate design, the introduction of specific groups in new ways, and the change of molecular structure.
Our chemical researchers should devote themselves to their research, gain insight into the mysteries of their reactions, improve their properties, and make this substance more effective in various fields such as industry and scientific research, thus contributing to human well-being.
Synonyms & Product Names
Synonyms and trade names of 2,4-difluoro-5-chloro-1-nitrobenzene
2,4-difluoro-5-chloro-1-nitrobenzene. This chemical substance is in the industry, and synonyms and trade names are quite key. Its synonyms are either derived from its chemical structure characteristics, or according to traditional naming conventions.
As far as synonyms are concerned, it is named from the perspective of its elemental composition and atomic arrangement, so that people in the industry can know its chemical essence. Trade names are often considered for commercial promotion needs, simple and easy to remember, and unique. Or contain the name of a research and development company, or have a unique meaning to help market identification.
Although there are no widely circulated multiple synonyms and trade names, they may emerge in the future with in-depth research and application expansion. At that time, industry communication and product promotion relied on accurate and clear synonyms and trade names to avoid confusion and promote the smooth development of the industry.
Safety & Operational Standards
Specifications for safety and operation of 2,4-difluoro-5-chloro-1-nitrobenzene
F 2,4-difluoro-5-chloro-1-nitrobenzene is an important substance in chemical research. If you want to use it, you must first clarify its safety and operation specifications in order to obtain its benefits and avoid its harm.
In terms of safety, this substance is dangerous. Its nitro structure makes it oxidizing, and it is easy to cause fire when encountering flammable materials. Therefore, when storing, it should be kept away from fire and heat sources, and placed separately from flammable and combustible materials. And because it contains halogen atoms, it may release toxic halogenated hydrogen gas when heated or exposed to chemical reactions. Therefore, the operation should be carried out in a well-ventilated place. If conditions permit, a fume hood should be set up to ensure that the experimenter is protected from toxic gases.
Operating specifications are also crucial. When taking it, it is necessary to wear appropriate protective equipment, such as gloves and goggles, to prevent it from coming into contact with the skin and eyes. If it comes into contact accidentally, rinse it with plenty of water quickly and seek medical attention in time. When weighing, the action should be steady and accurate, and the powder should not be allowed to fly, so as not to be inhaled into the body. During the reaction process, the reaction conditions, such as temperature, pressure, and the proportion of reactants, must be strictly controlled. Because its reactivity is affected by many factors, a slight poor pool may cause the reaction to go out of After the reaction is completed, the product treatment should not be ignored. In accordance with relevant environmental protection regulations, properly dispose of waste and do not discard it at will to avoid polluting the environment.
In short, the research and use of 2,4-difluoro-5-chloro-1-nitrobenzene must abide by safety and operating standards in order to ensure the smooth operation of the experiment and ensure the safety of personnel and the environment.
Application Area
Today there is a product named 2,4-difluoro-5-chloro-1-nitrobenzene. This product has its uses in many fields.
In the field of medicine, it can be used as a key intermediate, assisting in the synthesis of medicine, and making great contributions to treating diseases and saving people. Because of its special chemical structure, it can participate in complex reactions and make a good medicine against diseases.
In the field of materials, it also has extraordinary performance. It can be used to create special materials, endowing materials with unique properties, such as enhancing their stability, corrosion resistance, etc., so that materials can play an important role in special environments.
In addition, it is an indispensable reagent in the path of scientific research and exploration. With its characteristics, researchers carry out various experiments, deeply explore the mysteries of matter, promote the continuous progress of chemistry, and lay the foundation for human cognition of the world and improvement of life. Its wide application fields are the key elements of chemical research and production.
Research & Development
In recent years, I have focused on the research of chemical products, focusing on 2,4-difluoro-5-chloro-1-nitrobenzene. This material has special properties and is useful in various fields.
At the beginning, I studied its craftsmanship. After several trials, I observed the ratio of raw materials, temperature and temperature changes, and hoped to obtain the best method. The process is difficult, and I often encounter obstacles, but I have not given up.
Next, study its properties. In different media, observe its reaction, explore its chemical activity, and clarify its characteristics.
Today, its application is gradually widening. In the field of medicine, it is the basis for synthesizing good medicines; in terms of materials, it can help the birth of new materials. I hope that in the future, this product will continue to be researched and developed to a greater extent, seeking more well-being for the world, and expanding the world in the path of chemical industry.
Toxicity Research
The study of material properties is related to the safety of the people. Today there is a product named 2,4-difluoro-5-chloro-1-nitrobenzene, and the study of its toxicity is quite important.
This product also contains fluorine, chlorine, nitro and other groups, or has special chemical activity. Fluorine is very active, often changing the properties of molecules; chlorine is also active, affecting its chemical properties and toxicity; nitro is highly oxidizing, or highly toxic.
Toxicity test, or involving living things. The way into the body, the mouth, nose, and skin can be used. After entering the body, it may disturb the biochemical process and break the stability of cells. Looking at animals, there may be physiological abnormalities and organ damage. Its long-term effects cannot be ignored, or it may cause chronic diseases and have far-reaching consequences. Therefore, it is the heavy responsibility of chemical researchers to study its toxicity, understand its harm, and protect the well-being of the public.
Future Prospects
I have dedicated myself to the research of 2,4-difluoro-5-chloro-1-nitrobenzene. In today's world, chemical technology is improving day by day, and this compound has emerged in various fields with great potential.
In the field of pharmaceutical creation, it is expected that in the future, it may be based on this to develop special drugs, heal diseases, and save people from illness. In material science, it is expected to use its characteristics to develop new materials to make utensils stronger, tougher, and more extraordinary.
Although the current research is still on the way, I am full of expectations. I firmly believe that with time and unremitting research, we will be able to explore its subtlety and fully exert its advantages. At that time, this 2,4-difluoro-5-chloro-1-nitrobenzene will surely be able to benefit the world, paint a magnificent new chapter for the advancement of science and technology, and achieve future brilliance.
Where to Buy 2,4-Difluoro-5-Chloro-1-Nitrobenzene in China?
As a trusted 2,4-Difluoro-5-Chloro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Difluoro-5-Chloro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluoro-5-chloro-1-nitrobenzene?
2% 2C4-diene-5-bromo-1-naphthyl is a compound structure fragment in the field of organic chemistry. Its main uses often involve organic synthesis, materials science, medicinal chemistry and other fields.
In the field of organic synthesis, it can be used as a key intermediate. Through various chemical reactions, such as coupling reactions, substitution reactions, etc., it can be combined with other organic molecules to construct complex organic structures, paving the way for the synthesis of organic compounds with specific structures and functions.
In the field of materials science, the introduction of compounds containing this structure into polymer materials can endow materials with special optoelectronic properties due to the unique electronic properties and spatial configuration of the structure. For example, the preparation of materials with specific light absorption, emission or electrical conductivity shows application potential in optoelectronic devices, such as organic Light Emitting Diode (OLED), solar cells and other fields.
In the field of medicinal chemistry, due to its structural particularity, it may interact with specific targets in organisms and have potential biological activity. Medicinal chemists use this as a basis for structural modification and optimization to develop innovative drugs with therapeutic efficacy, which are expected to play therapeutic effects on specific disease targets.
As "Tiangong Kaiwu" says: "The craftsmanship of the world depends on exquisite things as the foundation, and can become extraordinary tools." This compound structure fragment is also the cornerstone of craftsmanship. It has been skillfully designed and used in many fields, contributing to scientific progress and technological innovation, helping humans create novel and practical materials and drugs, and promoting the development of related fields.
What are the physical properties of 2,4-difluoro-5-chloro-1-nitrobenzene?
2% 2C4-diene-5-halogen-1-alkynylbenzene compounds have unique physical properties.
The morphology of this compound is either liquid or solid at room temperature, depending on the type of halogen atom, the structure and number of substituents. If the halogen atom is fluorine, its atomic radius is small, the intermolecular force is relatively weak, or it is more likely to be liquid; if it is iodine, the atomic radius is large, the intermolecular force is enhanced, and the possibility of solid state is higher.
Its color, in pure state, is mostly colorless or light yellow, but the color may change due to impurities or specific light and temperature.
In terms of melting point and boiling point, due to the existence of alkynyl and diene structures, the intermolecular force is enhanced, and the melting point and boiling point are higher than those of ordinary benzene derivatives. And the halogen atom is electronegative, forming a polar bond, so that there is a strong dipole-dipole force between molecules, and also increases the melting boiling point. For example, when the chlorine atom is substituted, the boiling point or in a specific range, the bromine atom is substituted, and the boiling point is further increased due to the increase of atomic weight and the enhancement of intermolecular force.
In terms of solubility, this compound is an organic compound. According to the principle of similar phase solubility, it can be soluble in common organic solvents, such as ether, dichloromethane, chloroform, etc. Because of its polar group, its solubility in polar organic solvents But overall, the solubility in water is poor, because the molecular polarity is not enough to overcome the hydrogen bonding between water molecules.
The density is usually higher than that of water, due to the variety of atoms in the molecule, the relatively complex structure, and the high mass per unit volume. In practical applications and operations, this characteristic should be paid attention to, such as liquid-liquid separation operations, which may be in the lower layer.
Is the chemical property of 2,4-difluoro-5-chloro-1-nitrobenzene stable?
The chemical properties of 2% 2C4-diene-5-halo-1-naphthalene benzene are relatively stable. In this compound, the naphthalene group is connected to the benzene ring to form a relatively rigid structural framework. Both the naphthalene ring and the benzene ring have a conjugated system, and the conjugation effect reduces the molecular energy and improves the stability.
From the perspective of electronic effect, the naphthalene group interacts with the benzene ring, and the electron cloud distribution tends to average, enhancing the molecular stability. In the 2,4-diene structure, the double bond is conjugated to form a large π bond, which further reduces the system energy. The conjugated double bond system can undergo a variety of reactions, but the reaction conditions are relatively mild. Due to the stabilization of the conjugated structure, the reaction is not too active and difficult to control.
The existence of 5-halogen atoms, although the electron cloud distribution will change due to its electronegativity, has no subversive effect on molecular stability as a whole. The induction effect and conjugation effect of halogen atoms check and balance each other to maintain molecular stability to a certain extent. In addition, the conjugation system of the whole molecule is huge, so that the chemical properties of 2% 2C4-diene-5-halogen-1-naphthalene benzene are relatively stable under common conditions. In storage and general operating environments, it is not easy to spontaneously undergo violent chemical reactions and deteriorate.
What are the synthesis methods of 2,4-difluoro-5-chloro-1-nitrobenzene?
The synthesis method of 2% 2C4-diene-5-halogen-1-naphthyl nitrile is not directly described in "Tiangong Kaiwu", but it can be deduced from the wisdom of ancient chemical processes and the synthesis of related substances.
Ancient chemical processes rely on the accumulation of practice and experience inheritance. Significant achievements have been made in the fields of metal smelting, alchemy and pharmaceuticals, and ceramic firing, which contain many chemical change principles, which can provide ideas for the synthesis of 2% 2C4-diene-5-halogen-1-naphthyl nitrile.
To synthesize this substance, you can first choose the raw material. In ancient times, although there were no modern rich and fine chemical reagents, natural substances containing naphthalene, alkene, and halogen elements could be found. For example, some plants and minerals can be extracted, transformed, or can be used as starting materials.
is based on natural naphthalene substances, or the target structure can be gradually constructed by oxidation, reduction, substitution and other reactions. In ancient alchemy, heating, roasting, etc. were often used to promote reactions between substances, which may be used to adjust the structure of naphthalene rings and introduce ethylene bonds.
When introducing halogen atoms, the application of ancient halides can be investigated. Sea halogen and some halogen-containing minerals can be treated to provide halogen sources. Through clever reaction conditions, halogen atoms can be replaced at specific positions.
The introduction of nitrile groups can be converted by nitrogen-containing substances in ancient chemical processes. For example, some nitrogen-containing natural products or compounds, after appropriate treatment, may react with existing structures to form nitrile groups.
The synthesis process requires careful control of the reaction conditions. Although there were no precision instruments in ancient times, the appropriate conditions could be explored based on the experience of observing flames, temperature feel, and reaction time control.
Although this specific synthesis is not contained in "Tiangong Kaiwu", the wisdom and craftsmanship of the ancients provide a deep foundation for modern chemical research. Following the ancient ideas and methods, it may inspire a new way to synthesize 2% 2C4-diene-5-halogen-1-naphthyl nitrile in modern times.
What should be paid attention to when storing and transporting 2,4-difluoro-5-chloro-1-nitrobenzene?
2% 2C4-diene-5-bromo-1-naphthyl methanol has special physical properties, and all matters need to be taken care of when it is stored and transported.
When stored, it is advisable to choose a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature, humid environment may cause qualitative change. If it is at high temperature, the molecular thermal movement may cause its structure to change, resulting in changes in properties, and damage to its efficacy or reactivity. Humid environment, water vapor may interact with the substance, induce reactions such as hydrolysis, and damage its chemical structure.
And should be isolated from oxidants, acids, etc. The chemical structure of this substance contains alkenyl groups, bromine atoms, etc. In case of oxidants, alkenyl groups are easily oxidized, causing carbon-carbon double bonds to break and changing chemical properties. In case of acids, bromine atoms may be affected, causing substitution or elimination reactions, damaging their purity and structural integrity.
When transported, the packaging must be strong and tight. Choose suitable packaging materials, such as containers with corrosion resistance and sealing, to prevent leakage. Because of its bromine and other active groups, once leaked, or contaminated the environment, and it is dangerous to the health of the contacts. Handling also needs to be light and slow, to absorb vibration and impact. Vibration, impact or breaking the package, causing material leakage, and external forces or chemical reactions, such as intramolecular rearrangement, etc., causing material qualitative changes.
The transportation temperature also needs to be controlled. According to its physicochemical properties, set a suitable temperature range to avoid large temperature fluctuations. Excessive or low temperature can affect the stability of the substance, or cause crystallization, solidification, volatilization, etc., and change the chemical state and properties. In this way, the properties and quality of 2% 2C4-diene-5-bromo-1-naphthyl methanol can be maintained with proper storage.